If youre one of the 30 million American men affected by erectile dysfunction, youve likely spent some of your time looking into treatment options. The OG Little Blue Pill that made its name as the first prescription Erectile Dysfunction treatment. SPEDRA is used to treat erectile dysfunction, more commonly known . It contains an active ingredient, called Avanafil, which is a PDE5 inhibitor. According to the Times story, Anthony Sardella, a business research adviser at Washington University in St. Louis, told a House hearing last month that generic drug prices had fallen by about 50 . Both Stendra and Viagra have the potential to cause drug interactions when theyre taken with other medications and substances. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Common Name: avanafil Our guide Stendra side effects goes into more detail about these drug interactions and safety issues. The info in it doesn't seem accurate to me. Scott is one of the two founders of The Independent Pharmacy. Lastly, although it shouldnt stop the treatment from working, having a large or fatty meal before using Spedra can slow its effects down considerably. In this case, its a draw between the two medicines. You can learn more about Stendras side effects, including the specific risk of each type of side effect and interaction, in our detailed guide to Stendra side effects. Affordable and helps get the job done. Learn more about our editorial standards here. The recommended starting dose is 100 mg. STENDRA should be taken orally as needed as early as approximately 15 minutes before sexual activity. An additional study involving 440 adults with erectile dysfunction was also carried out, where Spedra was taken approximately 15 minutes before sexual activity. In short, Stendra and Viagra are both highly effective treatments for ED. The generic name for Viagra is sildenafil. All are subject to an online consultation and clinician approval. . More severe side effects, such as loss of vision and other vision-related issues, also appear more frequently among men who use Viagra than among Stendra users. Spedra MSDS, Boots.com is a trading name of Boots UK Limited. Affordable and helps get the job done. Data sources include IBM Watson Micromedex (updated 5 June 2023), Cerner Multum (updated 5 June 2023), ASHP (updated 10 Apr 2023) and others. Drinking alcohol may also decrease your ability to get an erection so drinking alcohol might undo the work you have done taking Spedra in the first place. Your session is about to timeout due to inactivity. This is the lowest dosage available at Boots. Many men try devices and medications such as Viagra to help them have sex after surgery. Its usually only prescribed when the lower dosages have proven ineffective but no side effects have occurred. However, you may still experience one or more side effects while using Stendra to treat ED. Spedra is an erectile dysfunction treatment for men aged 18 and over, and mustn't be used by women or children. In contrast, approximately 28 percent of men who take Viagra at the highest prescribed dose report experiencing headaches, making this side effect nearly three times as common among men who use Viagra to treat ED. In patients on stable alpha-blocker therapy, the recommended starting dose of Spedra is 50 mg. Patients should stop taking Spedra and seek prompt medical attention in the event of sudden decrease or loss of hearing. However, the interaction has not been studied. You can view and select an option from your account. Aside from Spedra, the other drugs in this class are Viagra, Cialis (Tadalafil) and Levitra (Vardenafil). . In a 1998 study, researchers noted that sildenafil, Viagras active ingredient, is an effective, well-tolerated treatment for men with ED. The strengths are Spedra 50mg, Spedra 100mg and Spedra 200mg, with prices starting from 23. Like with other ED treatments, its common for Stendra to become less effective as more time passes since you took the medication. Spedra is a medicine used to treat adult men with erectile dysfunction (sometimes called impotence), when they cannot get or keep a hard penis (erection) sufficient for satisfactory sexual activity. MANAGEMENT: Patients taking avanafil should avoid consuming large amounts of alcohol, which may increase the potential for orthostatic signs and symptoms including increase in heart rate, decrease in standing blood pressure, dizziness, and headache. Our full guide to Stendra explains how it works, why its effective and what you can expect if you use it to treat ED and improve your sexual performance. HIMS, HERS, H, and HIMS & HERS are trademarks of Hims, Inc. Get ED meds shipped to your door, if prescribed. Don't eat before taking Viagra, Levitra, or Spedra. For example, it could be that you experience negative side effects such as headaches, heart palpitations, or flushing. As long as youre still getting the effects you want from the 50mg dose, this would be the ideal solution. Moderate: arginine, metoprolol, metoprolol, Unknown: 5-hydroxytryptophan, charcoal, umeclidinium / vilanterol, anastrozole, aspirin, ipratropium, amoxicillin / clavulanate, rosuvastatin, sodium iodide, acetaminophen, tiotropium, cyanocobalamin, ascorbic acid, cholecalciferol, menaquinone, Major: cardiovascular disease, renal dysfunction, Moderate: priapism, alcoholism, hearing loss, liver disease, retinitis pigmentosa, seizure disorders. The proposed mechanism is inhibition of CYP450 3A4-mediated first-pass metabolism in the gut wall by certain compounds present in grapefruit. Efficacy of Avanafil 15 Minutes after Dosing in Men with Erectile Dysfunction: A Randomized, Double-Blind, Placebo Controlled Study. The information contained herein is not a substitute for and should never be relied upon for professional medical advice. Spedra 50mg will only be available to first time users of our online clinic if they have been previously prescribed Spedra 50mg by a GP or an online doctor. Administration with a meal results in a mean delay in Tmax of 1.12 to 1.25 hours, a 39% mean reduction in Cmax, and a negligible effect on AUC. By lowering the dosage, it might help to avoid these issues. Use the lowest dose that provides benefit. One increasingly popular medication for ED is Stendra -- a second-generation PDE5 inhibitor that received approval from the FDA in 2012. Spedra may be taken with or without food. Geriatric Use: Of the total number of subjects in clinical studies of avanafil, approximately 23% were 65 and over. It can get to work in just 15 mins, where other pills take 30 to 60 mins to start working. If the dosage youve been prescribed isnt effective the first time, this doesnt mean that it wont work for you at all. SPEDRA belongs to a group of medicines called phosphodiesterase type 5 inhibitors. Spedra comes in tablet form in 50mg, 100mg & 200mg doses; the active ingredient is avanafil. Statistics surmise that roughly 50% of men experience this issue to varying extents. Available for Android and iOS devices. And. For more information about treatment with Spedra, read the package leaflet (also part of the EPAR) or contact your doctor or pharmacist. This is because ED, in some cases, can be a symptom of an underlying medical condition such as Parkinsons disease, high blood pressure, diabetes, multiple sclerosis or heart disease. Facial flushing is a common side effect of both Stendra and Viagra. If you develop a persistent or painful erection after taking Stendra, you should seek emergency medical attention as soon as you can. You have a consultation being reviewed. This means that Stendra might be a more convenient option for you if youre looking for an ED medication thats quick to start working and can be taken with dinner. It is a PDE5-inhibitor, which means that it works in a similar way to other erectile dysfunction medications like Viagra. Once you have completed a free health consultation for our medical team, your prescription of Viagra Tablets can be delivered quickly and discreetly to your chosen address as soon as the next day. Like other ED medications, Stendra can cause drug interactions. Lastly, if you have a condition that might be aggravated by Spedra, taking the lowest dose can help to avoid any problems you might otherwise have with the treatment. There are three options in the range of avanafil dosages that can be adjusted as needed, with lower doses often proving effective while minimising the risks of side effects. Napumpujte ho antioxidantmi a vitamnmi! Developed for men aged 18 and over, Viagra contains the active ingredient sildenafil which causes blood vessels to the penis to relax. It works by blocking the phosphodiesterase enzyme, which normally breaks down a substance known as cyclic guanosine monophosphate (cGMP). And well only present data as clinically reliable if its come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Based on this plan, safety information has been included in thesummary of product characteristics and the package leaflet for Spedra, including the appropriate precautions to be followed by healthcare professionals and patients. Cyclic GMP causes smooth muscle relaxation and increased blood flow into the corpus cavernosum. Some authorities advise that grapefruit juice should be avoided within 24 hours prior to taking avanafil. If you are currently taking any other medication, you may need a different dosage. Because of this, its best to use Stendra as close to the time you plan to have sex as possible. This is the highest dosage available at Boots. The Patient Information Leaflet enclosed with your medicine will detail a full list of side effects. All information that appears on this website is intended for information purposes only and should be used to supplement, not replace, your relationship with your local healthcare professionals. However, if you have never taken this ED medication before, or if you take the stronger 200mg dosage of Spedra, you are more likely to experience side effects. Stop taking Spedra and see a doctor immediately if you notice any of the following serious side effects: It may be that you need urgent medical treatment, so you should see a medical professional as soon as possible. You have recently requested a change to your treatment plan which is under review. Unlike older ED medications such as Viagra (which contains the ingredient sildenafil), Cialis (which contains tadalafil) and Levitra (which contains vardenafil), Stendra is not available as a generic medication. In certain cases, such as if you are prescribed an alpha-blocker or a medication that inhibits the CYP3A4 enzyme, your healthcare provider may limit your Stendra dosage to 50mg, to be taken once per 24 hours. Support inquiries will not be addressed. The drugs are phosphodiesterase 5 (PDE5) inhibitors, and their brand and generic names, respectively, are Viagra (sildenafil), Cialis (tadalafil), Levitra (vardenafil), and Stendra (avanafil).. The only exception to this is if you take Spedra on a full stomach after a large meal in which case it can take as long as 90 minutes to work. Read on for more information about the different doses of Viagra, and find out what the right dose for you is. However, a greater sensitivity to medication in some older individuals should be considered. This is the most commonly prescribed dosage of Spedra and is the standard starter dose for those new to the drug. Patients presenting with any degree of vision loss should immediately discontinue use of all PDE5 inhibitors and seek medical attention. Viagra and generic medications containing sildenafil, on the other hand, typically take action in about one hour. If you want help choosing: Spedra takes the . Stendra is the brand name for avanafil, an erectile dysfunction drug marketed by Vivus, Inc. Its currently the only brand of avanafil thats available in the United States. Avanafil for treatment of erectile dysfunction: review of its potential. Experience with avanafil overdose is limited. Finding the most suitable erectile dysfunction medication can require some patience, but with the help of your prescribing clinician, you should be able to achieve the results you want in time. We strive to use primary sources and refrain from using tertiary references. These gummies deliver 15 mg of CBD, providing a convenient and all-natural way to enhance general . While it may seem like a different drug, avanafil is simply the active ingredient thats found in Stendra. Administration of avanafil 200 mg with alcohol at a dose of 0.5 g. The plasma concentrations of alcohol were not affected. Cialis helps you get and keep stronger erections with a daily or as-needed pill. Do not use for customer service inquires. The tour begins on Aug. 3 in Sterling Heights, Mi. The 100mg and 200mg Stendra tablets typically start to work within 15 minutes, meaning you can take them only a few minutes before you plan to have sexual intercourse. We may email you about the problem, but you can opt out of these communications any time you like. Sexual stimulation is still needed to produce an erection. . an erection). Spedra must only be taken once a day. 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