Do not thaw by putting in a water bath or microwaving. Do not use plastic containers in series connections. ZINACEF supplied as a frozen, sterile, iso-osmotic, nonpyrogenic solution in plastic containers is to be administered after thawing either as a continuous or intermittent IV infusion. If you are using the frozen pre-mixed solution, thaw the bag at room temperature or in the refrigerator. levels of both drugs, risk of nephrotoxicity, auditory, vestibular, other adverse effects (additive effects), cefuroxime sodium [17] Cefuroxime axetil is sold in tablet form in Turkey inder the brand names Aksef[18] and Cefaks. The usual adult dosage range for ZINACEF is 750 mg to 1.5 grams every 8 hours, usually for 5 to 10 days. It works by stopping the growth of bacteria. In bone and joint infections, 150 mg/kg/day (not to exceed the maximum adult dosage) is recommended in equally divided doses every 8 hours. bloating. Alka-Seltzer Plus Maximum Strength Cough, Mucus & Congestion Powe Alka-Seltzer Plus Maximum Strength Severe Sinus, Allergy & Cough. This is not a complete list of possible side effects. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. for 48 to 72 hours, followed by Zinacef axetil (Zinacef) oral therapy 500 mg twice a day for 7 to10 days. swelling of your face, lips, tongue, or throat. Throw away unused or expired drugs. UseZinacef (Injectable)exactly as directed on the label, or as prescribed by your doctor. It may also be used to prevent infection from certain surgeries. + + + Use only the diluent your doctor has recommended. Last updated on Dec 9, 2022. any drug without checking with your doctor. Keep all medications away from children and pets. lactulose efficacy (colonic metab. If the bag is thawed in the refrigerator, let it sit at room temperature at least 1 hour before using. Cefuroxime, sold under the brand name Zinacef among others, is a second-generation cephalosporin[1] antibiotic used to treat and prevent a number of bacterial infections. Cefuroxime belongs to a group of drugs called cephalosporin antibiotics. This medicine may affect certain lab tests. In cases of bacterial meningitis, a larger dosage of ZINACEF is recommended, 200 to 240 mg/kg/day intravenously in divided doses every 6 to 8 hours. DESCRIPTION Oral/parenteral second-generation cephalosporin Used for severe upper and lower respiratory tract infections, skin infections, otitis media, and surgical prophylaxis Oral tablets and suspension are not bioequivalent and are not substitutable on a milligram-per-milligram basis COMMON BRAND NAMES However, many people have no side effects or only have minor side effects. If you have questions about side effects, call your doctor. what signs you had. + [citation needed], In the U.S. it is marketed as Zinacef by Covis Pharmaceuticals since the company acquired the U.S. rights to the product from GSK. Hence, it may have greater activity against Haemophilus influenzae, Neisseria gonorrhoeae, and Lyme disease. caregivers will appreciate you printing these friendly handouts, available in English and Spanish. tenecteplase, cefuroxime sodium + Visit athenaInsight for proven, replicable best practices and data-driven strategies to enhance your practice's performance: com.epocrates.rxweb.beans.StringCollection@4779745f, com.epocrates.rxweb.beans.StringCollection@38ca55e3, com.epocrates.rxweb.beans.StringCollection@1af29098, com.epocrates.rxweb.beans.DrugOtherInfoBean@13b52653, com.epocrates.rxweb.beans.DrugOtherInfoBean@1fe273f6, acetaminophen/chlorpheniramine/dextromethorphan, acetaminophen/chlorpheniramine/dextromethorphan/phenylephrine, acetaminophen/chlorpheniramine/dextromethorphan/pseudoephedrine, acetaminophen/chlorpheniramine/phenylephrine, acetaminophen/dextromethorphan/phenylephrine, acetaminophen/dextromethorphan/phenylephrine/guaifenesin, acetaminophen/dextromethorphan/pseudoephedrine, acetaminophen/diphenhydramine/dextromethorphan, acetaminophen/diphenhydramine/phenylephrine, acetaminophen/doxylamine/dextromethorphan, acetaminophen/doxylamine/dextromethorphan/phenylephrine, acetaminophen/triprolidine/dextromethorphan, acetaminophen/triprolidine/dextromethorphan/phenylephrine, aclidinium bromide/formoterol fumarate inhaled, adenovirus type 4 and type 7 vaccine, live oral, Adenovirus Type 4 and Type 7 Vaccine, Live Oral, Advil Dual Action with Acetaminophen Back Pain, Alka-Seltzer Extra Strength Heartburn Relief Gum, Alka-Seltzer Extra Strength Heartburn ReliefChews, Alka-Seltzer Plus Maximum Strength Cold & Cough, Alka-Seltzer Plus Maximum Strength Cold & Cough PowerMax, Alka-Seltzer Plus Maximum Strength Cold & Flu Day, Alka-Seltzer Plus Maximum Strength Cold & Flu Day PowerMax, Alka-Seltzer Plus Maximum Strength Cold & Flu Night, Alka-Seltzer Plus Maximum Strength Cold & Flu Night PowerMax, Alka-Seltzer Plus Maximum Strength Cough & Mucus DM. In clinical trials, surgical intervention was performed when indicated as an adjunct to therapy with ZINACEF. For direct intermittent IV administration, slowly inject the solution into a vein over a period of 3 to 5 minutes or give it through the tubing system by which the patient is also receiving other IV solutions. Renal dysfunction: reduce dose. Give in equally divided doses. Drug class: second generation cephalosporins. Shake gently to disperse and withdraw completely the resulting suspension for injection. Tell your doctor if your condition lasts or gets worse. Tablet: The usual course of therapy is seven days (range 5 to 10 days). Generic name: Cefuroxime Injection [se-fyoor-OKS-eem] amikacin inhaled, monitor renal fxn, ototoxicity: combo may incr. These are not all the possible side effects of Zinacef. Bacterial or fungal overgrowth of nonsusceptible organisms may occur with prolonged or repeated therapy. Cefuroxime is a cephalosporin (SEF a low spor in) antibiotic that is used to treat bacterial infections of the ear, nose, throat, lungs, skin, bones, joints, bladder, or kidneys.Cefuroxime is also used to treat gonorrhea, meningitis, sepsis, or early Lyme disease.. Cefuroxime injection is sometimes given just before a surgery to prevent infection. Read all information given to you. Symptoms of ED include. This document does not contain all possible drug interactions. Zinacef axetil (Zinacef) should be taken after food for optimum absorption.. Sequential Therapy: Pneumonia: 1.5 g Zinacef three times a day or twice a day [intravenous (i.v.) New Salesforce jobs added daily. You may also report side effects at https://www.fda.gov/medwatch. When only serum creatinine is available, the following formula4 (based on sex, weight, and age of the patient) may be used to convert this value into creatinine clearance. Antibiotic medicines can cause diarrhea. This is not a complete list of side effects and others may occur. Do not refreeze. + Potentiated by probenecid. Cefuroxime is used to treat a wide variety of bacterial infections. Solutions of ZINACEF range in color from light yellow to amber, depending on the concentration and diluent used. Susceptible bacterial septicemia, lower respiratory or urinary tract, skin and skin structure, meningitis, bone and joint infections, gonorrhea. After constitution, ZINACEF may be given intravenously or by deep IM injection into a large muscle mass (such as the gluteus or lateral part of the thigh). Do not use longer than you have been told. with your doctor, nurse, pharmacist, or other health care provider. Cefuroxime can cause serious or life-threatening allergic reactions. bumetanide, monitor renal fxn: combo may incr. Save. cefuroxime levels, risk of adverse effects (renal transport inhibited), cefuroxime sodium risk of bleeding, incl. Available for Android and iOS devices. Store the tablets at room temperature away from moisture and heat. + gut microbiota restoration (antibiotic effects), cefuroxime sodium Salesforce Jobs in Milan, Lombardy, Italy. We comply with the HONcode standard for trustworthy health information. + sodium picosulfate, caution advised: combo may decr. You must check This information is currently not available for this drug. You may also report side effects at https://www.fda.gov/medwatch. gentamicin, monitor gentamicin levels, renal fxn, ototoxicity: combo may incr. Nursing mothers. Severe or complicated infections, bone and joint: 1.5g every 8 hours; life-threatening: 1.5g every 6 hours; meningitis: max 3g every 8 hours. furosemide, cefuroxime sodium For more information, ask your doctor or pharmacist. The following information includes only the average doses of this medicine. Manufacturer: Concordia Pharmaceuticals Inc. Monitor prothrombin time (in patients at risk), renal function. amikacin, monitor amikacin levels, renal fxn, ototoxicity: combo may incr. dienogest (contraceptive), cefuroxime sodium ZINACEF is available as a frozen, iso-osmotic, sterile, nonpyrogenic solution with 1.5 g of cefuroxime as cefuroxime sodium. Cefuroxime injection is given into a muscle or a vein, usually for 5 to 10 days. Penicillin allergy. unusual tiredness or weakness. A number of factors can affect how long a urinary tract infection (UTI) lasts including how severe it is, what caused it and the treatment taken for it. TwistVialTM vials that have been joined to compatible diluent containers and activated to dissolve the drug are stable for 24 hours at room temperature or for 7 days under refrigeration. Available for Android and iOS devices. + alteplase, monitor bleeding s/sx, especially w/ prolonged and/or high-dose cefuroxime tx: combo may incr. There are numerous home remedies that claim to treat or prevent urinary tract infections (UTIs), but they're not well-studied and the evidence is mixed. Tell your doctor about the allergy and risk of bleeding, incl. If you are 65 or older, use Zinacef with care. This medication may interfere with certain lab tests (including certain urine glucose tests), possibly causing false test results. When expanded it provides a list of search options that will switch the search inputs to match the current selection. sodium picosulfate efficacy (colonic metab. In bone and joint infections, a 1.5-gram dose every 8 hours is recommended. Cefuroxime is a semisynthetic, broad-spectrum, cephalosporin antibiotic for parenteral administration. Solutions of premixed ZINACEF range in color from light yellow to amber. In bone and joint infections, a 1.5-gram dose every 8 hours, usually for 5 to days! 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