In the above examples, your veterinarian has done all the math for you, but there may be times when they dont instead giving you dosing information that requires you to do some math to figure out the exact amount an individual requires per dose. Nest boxes should be added to the cages 2829 days after breeding. In the classic blind technique, the rabbit is placed in a sternal position with the head held and the nose pointing at the ceiling. Merck & Co., Inc., Rahway, NJ, USA(known as MSD outside of the US and Canada) is dedicated to using the power of leading-edge science to save and improve lives around the world. Prolonged opiate exposure at the above mentioned dosages has not been associated with major GI stasis that has been observed in omnivores. o [ canine influenza] Enter search terms to find related veterinary topics, multimedia and more. Normal body temperature is 100.5104F (39.640C). Example 2: Administer 125 mg of Hypomed. C. Determine the concentration needed to accurately dose the, animal. The Merck Veterinary Manual was first published in . Although the use of alpha 2 agonists is effective, serious cardiovascular depressant effects can be observed. This Forum and Store have separate secure Sign Ins. Example 2: 50 mcg/kg. We already covered this above, but it bears repeating. Someone can intentionally cause direct harm (e.g., punitively cutting a sheep's skin while shearing them) or unintentionally cause direct harm (e.g., your hand slips while shearing a sheep, causing an accidental wound on their skin). The device sits on top of the glottis and seals the surrounding structures, creating an airtight connection between the trachea and the tube. The ET is advanced along the hard palate to the back of the throat until condensation can be seen within the lumen of the ET. When not restrained properly and securely, fractures or luxations of lumbar vertebrae can easily follow struggling. The units in our denominator and our residents weight must match. Feedings vary from 1/2 tsp to 2 tbsp, depending on the age of the kits. Does that are not receptive have a whitish pink vaginal color with little or no moisture. Copyright 2023 Merck & Co., Inc., Rahway, NJ, USA and its affiliates. If a rabbit appears to be very stressed or excited, a sedative may be indicated to avoid iatrogenic injuries. If a doe has not kindled by day 32 of gestation, oxytocin (12 IU) should be given to induce parturition; otherwise, a dead litter is almost always delivered sometime after day 34. Please confirm that you are a health care professional. Sometimes, the amount you need to administer will be smaller than what you have on hand. So, you are starting your dilution with 20ml of Ketamine and 1 ml of Xylazine, which have been taken directly off the pharmacy shelf. If boxes are added too soon, the does foul the nests with urine and feces. We do not control or have responsibility for the content of any third-party site. o [pig guinea] Castration is mainly for the benefit of the owner. The ET can be used to disengage the glottis from the soft palate, and then introduced into the glottis and down the trachea. Similarly, if you are converting milligrams to micrograms or milliliters to liters (or other units), think about whether you should end up with a larger or smaller numeral. Blood can be collected from the cephalic vein, lateral saphenous vein, and the jugular vein. When the concentration is written as a percentage, this indicates the number of grams of medication per 100 mL of solution. Laboratory animals are extremely small when compared to the animals that the injectable drugs are made for. Remember that when converting from pounds to kilograms, you will always end up with a smaller numeral. Example 4: 1 cc/100 lbs. Calculate the dose, and then click the toggle to check your answer. Use of them does not imply any affiliation with or endorsement by them. A fine, absorbable monofilament suture should be used for routine double-layer closure of the stomach wall and incorporate, but not penetrate, the gastric mucosa. Use to remove results with certain terms If the rabbit does not eat within 23 hours after surgery, the analgesic protocol should be reevaluated. The long and narrow pharynx and large tongue make rabbits difficult to intubate. be expanded for drug dose calculation in an attempt to more accurately administer cytotoxic drugs to children. As rabbit owners, it's our duty to provide our pets with the best life possible. Tiletamine/zolezapam (3 mg/kg) is another safe and practical option, but rabbits tend to recover more slowly from this drug, and it has been reported to cause renal problems at higher doses. If your veterinarian is instructing you to administer medication that they are not directly supplying you with, its a good idea to double-check that you are both working with the same concentration in mind to avoid dosing issues. Dosage Range: Frequency: Route: Info/Warning: This page has been accessed s="na";c="na";j="na";f=""+escape(document.referrer) s=screen.width;v=navigator.appName if (v != "Netscape") {c=screen.colorDepth} else {c=screen.pixelDepth} j=navigator.javaEnabled() function pr(n) {document.write(n,"\n");} NS2Ch=0 if (navigator.appName == "Netscape" && navigator.appVersion.charAt(0) == "2") {NS2Ch=1} if (NS2Ch == 0) { r="&size="+s+"&colors="+c+"&referer="+f+"&java="+j+"" pr("<\/A>")}times since February 8, 1999. Enrofloxacin: Oral Gel Medicated gel for oral use. When you are just starting out, you may want to compare your answer to an online conversion calculator just to be safe. Often, but not always, there will also be information that states the concentration in terms of milligrams per milliliters. o [pig guinea] If a doe is unable to nurse all the kits effectively, kits may be fostered by removing them from the nest box during the first 3 days and giving them to a doe of approximately the same age with a smaller litter. If you ever end up with a larger numeral when converting pounds to kilograms, this is a clear indication that theres been a miscalculation, and youll need to do the conversion again. The important information here is as follows: Desired = 500 mg (what the veterinarian instructed us to administer)Have = 100 mg (the dose we have on hand, found on the HypoCure label)Quantity = 1 ml (the unit of measure that contains the 100 mg, found on the HypoCure label). Similarly, pay attention to whether your veterinarian is using kilograms or pounds in their instructions and make sure you follow suit. Here are some examples of dosing information that requires some math in order to figure out the exact dose amount: In each example above, the information we need in order to calculate the dose is in bold. Always Ask For Clarification If Needed!If you are ever unclear about your veterinarians instructions, particularly if they use abbreviations or language you are not familiar with, make sure you ask for clarification. Most techniques for physical examination suitable for dogs and cats may be applied to rabbits. If these are not familiar to you, its important to have a basic understanding of what they mean, so lets look at them a bit more closely. This content is intended for patient counseling purposes only. With an online account, access our extensive formulary or over 40,000 unique items - 24 hours a day, 7 days a week. Heres another example using the slash instead of writing out per. This example also differs from the others because the specified weight is in pounds rather than kilograms. ( Note for mobile user: Swipe left at the table to view the mean recommended dose and volume. Supportive care for rabbits often includes aggressive IV fluid support. What are we about? Your veterinarian will tell you what medication the individual needs, how much they need, how to administer it, how often they need it, and how long the treatment should last. If you are seeing rodents in a. small animal practice, you may only carry the small animal concentration of Xylazine (20mg/ml). A species-specific supraglottic airway device is placed in the oral cavity and advanced caudally until it sets in place automatically. All rights reserved. Dr Chris Hayhow water treatment 5cc to one gallon water-for 5 days (prevention) water treatment 5cc to one gallon water-for 5 days (treatment) or 1cc orally for 15 pounds of rabbit-for 5 days (1/4 cc orally for 3.75 pound rabbit) Sulmet 2 tablespoons per gallon of water. Download Calculating Drug Doses for Laboratory Animals | VM 20400 and more Veterinary medicine Lab Reports in PDF only on Docsity! Merck & Co., Inc., Rahway, NJ, USA (known as MSD outside of the US and Canada) is dedicated to using the power of leading-edge science to save and improve lives around the world. Direct visualization of the epiglottis and ET placement can also be accomplished by using a laryngoscope with a Miller 0 blade, a rabbit oral speculum, and cheek dilators. Lets revisit the examples above to demonstrate how to use this formula. Example 1: Administer 500 mg of Hypomed. The answers provided on this board are for general guideline purposes only. Submit Office Orders & Patient Prescriptions. This improved formula has two basic merits - it is easy and pleasant to take by mouth and it works faster than any usual pill taken with water. Lastly, chewable tablets that are split may not have even distribution of the drug in the tablet, which may result in over- or under-dosing. In the following examples, we know exactly how much to administer at any one time (bolded below), and we also know the administration route, the frequency, and the duration: So long as you are trained in proper administration techniques, these instructions are pretty straightforward. Reggie weighs 200 lbs. As with the examples above, we are going to focus only on the dose. Buy the injectible form and a syringe with 1/10 cc markings, and you won't be overdosing your rabbits by many times the recommended dose. The combination of ketamine (1020 mg/kg, IM) and dexmedetomidine (0.1250.25 mg/kg, IM) provides adequate anesthesia; ~ of the original dose can be repeated if anesthesia needs to be prolonged. Particularly when looking at liquid medications, do not confuse the size of the bottle with the concentration. If you have any questions please talk to your rabbit-savvy vet! Opioids such as oxymorphone or hydromorphone can readily be used and have not been shown to cause GI stasis. Quantity (Q) is the unit of measure that contains the dose on hand. A second technique involves placing the rabbit in lateral recumbency with the head dorsiflexed. Ordering patient medications is easy. If a dilution is needed, then you must look at the prescribed dosage for the animal (i.e. The extensive use of rabbits in toxicity studies has led to an abundance of information on the actions of drugs on rabbit tissue, both in vivo and in vitro, but there is a lack of data on their efficacy in the treatment of clinical disease. Which, after we multiply the numerators and denominators, becomes: We then divide 130 cc by 100 to get our answer: Because we didnt have just 1 in the denominator, this calculation took an extra step, but we now know the individual needs to receive 1.3 cc per dose. This will help to avoid wasting drugs if the calculations need to be revised. Using medications without veterinary input could result in harmThe infliction of mental, emotional, and/or physical pain, suffering, or loss. d. Determine the amounts of drugs/sterile water needed to dilute the prescribed drugs. Determine the amounts of drugs/sterile water needed to dilute the, prescribed drugs. We do not control or have responsibility for the content of any third-party site. The young are born naked, blind, and deaf. If you put this ratio in the same format as the original example it comes to 100:1. If you have any questions please talk to your rabbit-savvy vet! 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