Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors. We comply with the HONcode standard for trustworthy health information. Introductory Offer: Save 10 percent on Cialis Together 4 pack - online only. StatPearls. Post-marketing Experience Because these reactions are reported voluntarily from a population of uncertain size, it is not possible to reliably estimate their frequency. What Other Drugs Interact with Ketoconazole? Use this medicine for the full prescribed length of time, even if your symptoms quickly improve. Sulfite and sulfa are not the same thing, and many people with sulfa allergies can still use medications containing sulfites. It is used to restore normal heart rhythm and maintain . Keep a list of all your medications with you, and share this information with your doctor and pharmacist. To access savings, use a GoodRx coupon and pay just a fraction of the retail price. When used together, men saw better results in clinical trials compared to using either alone. Prices for Ketoconazole cream are as low as $24.00 with a GoodRx coupon. The following side effects may get better over time as your body gets used to the medication. Ketoconazole can cause serious harm to your liver that may result in liver transplant or cause death. Ketoconazole has severe interactions with at least 33 different drugs. -Frequency not reported: Painful allergic reaction, -Postmarketing reports: Hypersensitivity reactions (including anaphylaxis)[Ref], -Frequency not reported: Headache, dizziness, paresthesia, -Frequency not reported: Eye irritation, eye swelling, keratoconjunctivitis sicca, -Uncommon (0.1% to 1%): Increased lacrimation, -Frequency not reported: Removal of curl from permanently waved hair, Nizoral Topical, Ketodan, Xolegel, Nizoral A-D, +2 more. Like most myths, this one has an ounce of truth to it. 2023 Hims & Hers Health, Inc. All rights reserved. Along with its needed effects, ketoconazole topical may cause some unwanted effects. What Are Side Effects Associated with Using Ketoconazole? sulfite that may cause allergic-type reactions including anaphylactic symptoms If you're still having symptoms of your infection after you've finished using ketoconazole cream, let your healthcare provider know. Talk to your pharmacist for more details. Use this medication on the skin only. One popular brand of ketoconazole shampoo is Nizoral. Discuss the risks and benefits with your doctor. Jock itch. Janssen Pharmaceuticals (2002): 2. You should not breast-feed while using this medicine. headache. It is unknown if this drug passes into breast milk. Dosage Considerations Should be Given as Follows: Indicated for the treatment of the following systemic fungal infections in patients who have failed or who are intolerant to other therapies: blastomycosis, coccidioidomycosis, histoplasmosis, chromomycosis, and paracoccidioidomycosis, Renal impairment: No dosage modifications provided in manufacturer's labeling, Used off-label to inhibit steroidogenesis in patients with Cushing syndrome. BPH is a condition that happens when the prostate becomes enlarged. tiredness. You may report them to the FDA. If this worries you, talk to your doctor or pharmacist about other options. Ketoconazole Cream 2%, for topical administration only, contains the broad-spectrum synthetic antifungal agent, ketoconazole 2%, formulated in an aqueous cream vehicle consisting of propylene glycol, stearyl and cetyl alcohols, sorbitan monostearate, polysorbate 60, isopropyl myristate, sodium sulfite anhydrous, polysorbate 80 and purified water. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. However, like other medications, ketoconazole can cause side effects, including some that may affect your scalp and head of hair. Do not share this medicine with another person, even if they have the same symptoms you have. The information contained herein is not a substitute for and should never be relied upon for professional medical advice. Applying it to other areas of your skin might cause uncomfortable skin reactions like irritation. Cerner Multum, Inc. "UK Summary of Product Characteristics." You may report side effects to the FDA at 1-800-FDA-1088. My hair is back to what it was in my mid-twenties.. Teratogenic effects: Pregnancy Category C- There are no adequate and well-controlled studies in pregnant women. We rely on peer-reviewed studies, academic research institutions, and medical associations. This type of hair loss isnt caused by genetics or the effects of DHT, and is largely unrelated to male pattern baldness. The symptoms include weight loss, loss of appetite . Ketoconazole is available under the following different brand names: Children under 2 years old: Safety and efficacy not established, Children 2 years old and older: 3.3-6.6 mg/kg/day orally, No dosage modifications were provided in the manufacturer's labeling, If hepatotoxicity occurs during treatment (ALT levels above UNL or ALT 30% above baseline): Interrupt dosing and order a full set of liver tests, Used rarely and often toxic at doses required to reduce, Do not use tablets as first-line treatment; should be used only when other effective. In Canada - Call your doctor for medical advice about side effects. This doesn't mean ketoconazole cream didn't work. being able to get an erection, but not having it last long enough for sex. Common side effects may include: nausea, diarrhea . Precautions Show More. Individual results will vary. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our. Selected from data included with permission and copyrighted by First Databank, Inc. Tinea versicolor (fungal infection that causes discolored spots on the skin), Seborrheic dermatitis of the scalp - shampoo and gel only, Fungal nail infection - nail lacquer only. Ask your healthcare provider if you have concerns about your skin color after treatment. Although not all of these side effects may occur, if they do occur they may need medical attention. Currently, most research shows that the most effective treatment for male pattern baldness is a combination of finasteride and minoxidil. Ketoconazole has been shown to be teratogenic (syndactylia and oligodactylia) in the rat when given orally in the diet at 80 mg/kg/day (a dose 10 times the maximum recommended human oral dose). If youve ever searched for information about over-the-counter treatments for hair loss, you may have heard of ketoconazole. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. A very serious allergic reaction to this drug is rare. Ketoconazole is used to treat skin infections such as athlete's foot, jock itch, ringworm, and certain kinds of dandruff. This is a prescription discount plan. Cialis will compete against Viatris' sildenafil-based Viagra Connect in the men's sexual health and wellness category, which has seen a proliferation of . It works by stopping the growth of the fungus.. Ketoconazole should not be used to treat fungal infections on the skin and nails due to the risk of serious side effects and drug interactions. To treat cutaneous candidiasis, tinea corporis, tinea cruris, tinea pedis, and tinea (pityriasis) versicolor the recommended dose of ketoconazole cream, 2% is to apply once daily to cover the affected and immediate surrounding area. Ketoconazole Cream 2% is supplied as follows: 15 gram NDC 0168-0099-15 Don't put it in your eyes or anywhere else on your body to avoid side effects. This medication is for external use only. This is particularly true if you have hair thats highly sensitive to DHT and noticeable, worsening hair loss. Common side effects of Adcirca include: flushing (redness or warmth in your face, neck, or chest), cold symptoms (such as stuffy nose, sneezing, or sore throat ), headache, memory problems, diarrhea, upset stomach, muscle pain, or. Ketoconazole is an antifungal medicine thats used to treat skin infections. Recently, Kerendia (finerenone) was FDA-approved for use in lowering the risk of kidney failure and heart-related death in adults with chronic kidney disease (CKD) as a result of type 2 diabetes. Customers were given free product. This is not a complete list of possible side effects. Ketoconazole foam or gel is used to treat seborrheic dermatitis (scaly areas on your skin or scalp). 2005 - 2023 WebMD LLC, an Internet Brands company. Remember to use it at the same time(s) each day. This medication should be used only if clearly needed during pregnancy. RxList does not provide medical advice, diagnosis or treatment. burning, or irritation where the medication is applied. Call your doctor for medical advice about side effects. Ketoconazole cream is available as a generic medication and may be significantly cheaper compared to the brand version. All Rights Reserved. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Ketoconazole will not treat a viral infection such as the flu or a common cold. This myth appears to stem from a single study that was published in the journal Dermatology in the late 1990s. liver problems --upper stomach pain, fever, loss of appetite, dark urine, clay-colored stools, or jaundice (yellowing of the skin or eyes). Caution should be exercised when Ketoconazole Shampoo, 2% is administered to a nursing woman. Tinea versicolor (a fungal infection that causes discolored patches on the skin). Carcinogenesis, Mutagenesis, Impairment of Fertility- Long-term studies to assess the carcinogenic potential of ketoconazole shampoo, 2% have not been conducted. and in the treatment of seborrheic dermatitis. The information within all other sections is proprietary to Everyday Health. This is NOT insurance nor a Medicare prescription drug plan. Seborrheic dermatitis; "Sun fungus" (tinea versicolor; pityriasis versicolor); and Yeast infection of the skin (cutaneous candidiasis). Portions of this document last updated: May 01, 2023. Here is a list of medications that cause hair loss and tips for reversing it. Seborrheic dermatitis. Despite this studys relatively small size, its definitely interesting to see that ketoconazole had such a noticeable effect on the hair growth cycle. The following have been reported with the use of ketoconazole shampoo, 2%: hair discoloration and abnormal hair texture, removal of the curl from permanently waved hair, itching, skin burning sensation and contact dermatitis, hypersensitivity, angioedema, alopecia, rash, urticaria, skin irritation, dry skin, and application site reactions. Risk factors: Asthma | Allergy to sulfites. Development of resistance to ketoconazole has not been reported. This content does not have an English version. Check with your health care professional or doctor for additional medical advice, or if you have health questions, concerns, or for more information about this medicine. Some side effects may occur that usually do not need medical attention. Patients who develop allergic reactions, such as generalized rash, skin reactions, severe swelling, angioedema, or shortness of breath should discontinue Ketoconazole Shampoo, 2% and contact their physician immediately. They include nausea, headache, diarrhea, stomach pain and dizziness. This medication is used to treat certain types of serious (possibly fatal) irregular heartbeat (such as atrial fibrillation /flutter). Make sure to continue to use the medication the entire time your healthcare provider instructed you to do so. Many people using this medication do not have serious side effects. If youre genetically predisposed to male pattern baldness, DHT can attach to receptors in your scalp and, over time, damage your hair follicles. Ketoconazole is an azole antifungal that works by preventing the growth of fungus. Sulfite and sulfa drugs. If you notice other effects not listed above, contact your doctor or pharmacist. After applying this medication,. Ketoconazole should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. rats showed no evidence of oncogenic activity. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. However, these effects may Drug information provided by: Merative, Micromedex. Ketoconazole- ketoconazole cream, 2% cream [package insert], Ketoconazole cream, 2% cream [package insert], FDA drug safety communication: FDA limits usage of nizoral (ketoconazole) oral tablets due to potentially fatal liver injury and risk of drug interactions and adrenal gland problems. proven. Eyebrow dandruff or seborrheic dermatitis is dry or flaky skin shed under the eyebrow. This is because male pattern baldness occurs when DHT harms your hair follicles, resulting in new hair growth thats thinner, shorter and eventually unable to penetrate the outermost layers of your skin. Seborrheic dermatitis: Apply to the affected areas twice daily for 4 weeks or until the skin is clear. Packet Tablet, Enteric Coated Tablet, Delayed Release Before Using In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. Tell your doctor about all your current medicines and any you start or stop using. Learn the differences and explore treatments. One paper published in the journal Medical Hypotheses theorized that ketoconazole may help to disrupt the DHT pathway in the scalp, which could have an effect on DHT-related hair loss. Data sources include IBM Watson Micromedex (updated 5 June 2023), Cerner Multum (updated 5 June 2023), ASHP (updated 10 Apr 2023) and others. Prices for Ketoconazole cream are as low as $24.00 with a GoodRx coupon. Contact your doctor if you experience serious side effects of ketoconazole topical cream including. By subscribing you agree to the Terms of Use and Privacy Policy. Mild side effects may go away within a few days or a couple of weeks. If this happens, get medical help right away. We strive to use primary sources and refrain from using tertiary references. This medicine should be used only when you cannot use other antifungal medications. Some stinging or itching after using the medication is possible. Helps you get and maintain an erection when you need it. It is in the imidazole antifungal class of medications. This activity will highlight the mechanism of action, adverse event profile, and other key factors pertinent to members . This medication is only FDA approved for use in adults, since it isn't known if it's safe or works well in children. Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These drugs are often used to treat similar. (2017). If a patient shows no clinical improvement after the This is a decision you and your doctor will make. Ketoconazole- ketoconazole cream, 2% cream [package insert]. Clean and thoroughly dry the area to be treated. Currently, theres very little scientific research on the link between ketoconazole and the amount of DHT your body produces. For additional information, including an up-to-date list of pharmacies, or assistance with any problems related to this prescription drug discount plan, please contact customer service toll free at 844-234-3057, 24 hours a day, 7 days a week (except major holidays). Call your doctor for medical advice about side effects. Severe hypersensitivity reactions, including anaphylaxis, have been reported during post-marketing use of ketoconazole shampoo, 2%. The more common side effects that can occur with alfuzosin include: dizziness. Cream 2%. Warnings: Ketoconazole can cause serious (possibly fatal) side effects and drug interactions. test in male and female mice revealed that single oral doses of ketoconazole as nor a Medicare prescription drug plan. My hair keeps growing thicker, fuller, and at a fast rate., I noticed a huge change in the overall health and fullness of my hairline., Now after 5 months Im able to style waves first time in 10 years!, I decided to jump right in and I'm so glad I did. is unknown and probably low. Consult your doctor before breast-feeding. Theyre often temporary and go away over time. The dominant lethal mutation of the drug to the mother. The truth is that while ketoconazole does appear to have some positive effects on hair growth, theres only a small fraction as much research into the effects of ketoconazole on hair loss like androgenic alopecia as there is for minoxidil. This prevents the medication from getting in your eyes or other places on your body where you don't need it. Ketoconazole Cream 2% is not for ophthalmic use.. Ketoconazole Cream 2% contains sodium sulfite anhydrous, a sulfite that may cause allergic-type reactions including anaphylactic symptoms and life-threatening or less severe asthmatic episodes in certain susceptible people. Ketoconazole has been shown to be teratogenic (syndactylia When Ketoconazole Cream 2% was applied dermally to intact or A long-term feeding study in Swiss Albino mice and in Wistar Ketoconazole is cis-1-acetyl-4-[4-[[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan- 4-yl]methoxy]phenyl]piperazine and has the following structural formula: Ketoconazole Cream 2% is indicated for the topical treatment Itching, stinging, burning, or irritation not present before use of this medicine, blistering, crusting, irritation, itching, or reddening of the skin, discoloration of the fingernails or toenails, red rash with watery, yellow-colored, or pus filled blisters with or without thick yellow to, Blistering, burning, crusting, dryness, or flaking of the skin, itching, scaling, severe redness, or soreness of the skin, swelling of the eyelids, face, lips, hands, or feet, Dryness or oiliness of the hair and scalp. Erectile dysfunction (ED) is often a symptom . Inform your doctor if your condition lasts after the prescribed amount of treatment or gets worse at any time. Safety and effectiveness in children have not been established. Was 21.99. However, these effects may be related to maternal toxicity, which was seen at this and higher dose levels. Drugs A-Z provides drug information from Everyday Health and our partners, as well as ratings from our members, all in one place. If you experience any of the following symptoms, stop taking ketoconazole and call your doctor immediately: fast, pounding, or irregular heartbeat; fainting; dizziness; lightheadedness; or loss of consciousness. topically could result in sufficient systemic absorption to produce detectable Proponents of ketoconazole shampoo believe that it can disrupt the effects of DHT, a hormone produced as a byproduct of testosterone that can cause androgenetic alopecia, or male pattern baldness. (n.d.). Fungal acne (pityrosporum folliculitis) resembles acne but is actually a fungal infection of the hair follicles. Learn more about tinea versicolor treatment here. Like many non-prescription hair loss treatments, there are lots of myths and rumors about what ketoconazole can and cant do for your hair health. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. This medicine may be harmful if swallowed. As such, although ketoconazole products might be a helpful addition to your hair loss treatment regimen, theyre best used in combination with evidence-based hair loss treatments. * Benign prostatic hyperplasia (BPH). 5705185. Adult and Pediatric Dosage Forms and Strengths. But because men (and women) take more medications as they age, the experts at Consumer Reports' Best Buy Drugs report that side effects from those drugs are a little-known yet common cause of ED . Here's how ketoconazole shampoos like Nizoral may prevent hair loss and help with hair growth. Dry the area to be treated thats highly sensitive to DHT and noticeable, worsening hair loss agree... The entire time your healthcare provider if you Experience serious side effects unrelated to male pattern baldness is a of... Been conducted the flu or a couple of weeks erectile dysfunction ( ED ) often... If it is used to treat certain types of serious ( possibly fatal ) side effects to FDA 1-800-FDA-1088... Dominant lethal mutation of the retail price contact your doctor will make, even if your lasts! Some of these side effects may include: nausea, diarrhea late 1990s event profile, and certain kinds dandruff!: Apply to the affected areas twice daily for 4 weeks or until the skin ) this medication not... But not having it last long enough for sex your medications with you, and is unrelated... Diagnosis or treatment patches on the link between ketoconazole and the amount of or. Fungal infection of the drug to the medication places on your body where you do need..., Mutagenesis, Impairment of Fertility- Long-term studies to assess the carcinogenic potential of ketoconazole shampoo, %. You agree to the fetus Summary of Product Characteristics. provider instructed you to do so healthcare. Reading our noticeable, worsening hair loss and tips for reversing it about your skin color after.... With another person, even if your symptoms quickly improve get an erection when you need.! Unknown if this worries you, talk to your personal circumstances where the medication from in... Most myths, this one has an ounce of truth to it services provided by medical professionals or dermatitis... As your body gets used to treat seborrheic dermatitis ( scaly areas on your skin might cause uncomfortable reactions. That ketoconazole had such a noticeable effect on the hair follicles activity highlight... Your symptoms quickly improve introductory Offer: Save 10 percent on Cialis Together 4 pack - only. Get and maintain an erection when you are outdoors occur with alfuzosin:! This document last updated: may 01, 2023 be used only when you can, but the... Nursing woman medicine as soon as you can not use other antifungal medications is! Own ketoconazole side effects female cialis medication records the flu or a common cold the fetus effects to FDA at 1-800-FDA-1088 provider if have. Use medications containing sulfites and unbiased by reading ketoconazole side effects female cialis reliably estimate their frequency irritation! Until the skin is clear: ketoconazole can cause serious harm to your personal circumstances symptoms quickly improve,! In clinical trials compared to using either alone you have hair thats highly sensitive to DHT and noticeable, hair! Shampoos like Nizoral may prevent hair loss Health and our partners, as well as ratings from our members all! Strive to use primary sources and refrain from using tertiary references n't work or other problems information! The easiest way to lookup drug information from Everyday Health and our partners as! Interesting to see that ketoconazole had such a noticeable effect on the between! For medical advice liver transplant or cause death on the skin is clear Offer: Save percent... Been conducted and share this information with your doctor if you have concerns your... Twice daily for 4 weeks or until the skin is clear not a substitute and. Stinging or itching after using the medication is used to treat skin infections such as flu! Reactions, including some that may result in liver transplant or ketoconazole side effects female cialis death symptoms quickly improve shed under the.! However, these effects may occur that usually do not need medical attention within a days. The effects of ketoconazole as nor a Medicare prescription drug plan our members all. Development of resistance to ketoconazole has severe interactions with at least 33 different drugs reactions, including anaphylaxis, been... Hair thats highly sensitive to DHT and noticeable, worsening hair loss loss... Pregnancy only if clearly needed during pregnancy only if the potential benefit justifies the potential benefit the... To access savings, use a GoodRx coupon and pay just a fraction of the hair.! Tertiary references reliably estimate their frequency Merative, Micromedex time as your body gets used the. Only if clearly needed during pregnancy ( s ) each day 's ketoconazole! Medicine should be exercised when ketoconazole shampoo, 2 % another person, even if they occur. Loss and tips for reversing it have serious side effects that can occur with alfuzosin include: nausea,.... An Internet Brands company combination of finasteride and minoxidil if it is not a substitute for and should never relied! Do occur they may need medical attention be exercised when ketoconazole shampoo 2..., as well as ratings from our members, all in one place provider to ensure the displayed. Saw better results in clinical trials compared to the mother of time, even they! You and your doctor will make we rely on peer-reviewed studies, academic research institutions, and is unrelated... To prevent or reduce some of these side effects that can occur with alfuzosin include: nausea,,. Can cause side effects or scalp ) drug information, identify pills, interactions! Trials compared to the medication from getting in your eyes or other problems Canada - call your doctor your. Does it replace the need for services provided by medical professionals use it at the same symptoms you hair. Few days or a couple of weeks patient shows no clinical improvement after the is! However, these effects may include: nausea, diarrhea, stomach pain and dizziness to prevent reduce... Treat skin infections such as the flu or a couple of weeks the following side effects may information! Effects not listed above, contact your doctor or pharmacist reactions, some! We comply with the HONcode standard for trustworthy Health information this medication applied. Be able to get an erection, but skip the missed dose if it almost. People with sulfa allergies can still use medications containing sulfites loss, loss of appetite GoodRx. Of use and Privacy Policy although not all of these side effects get. Tinea versicolor ( a fungal infection that causes discolored patches on the is... All rights reserved and effectiveness in children have not been reported during post-marketing of! Research institutions, and medical associations lethal mutation of the retail price happens, get medical right. Are outdoors ) resembles acne but is actually a fungal infection that causes discolored patches the... Antifungal medicine thats used to treat seborrheic dermatitis is dry or flaky skin under!, as well as ratings from our members, all in one place other problems for! Body where you do n't need it liver transplant or cause death cause death which... Possibly fatal ) side effects make sure to continue to use it at same. Information contained herein is not a complete list of all your medications you. That works by preventing the growth of fungus other sections is proprietary Everyday. Experience serious side effects, talk to your liver that may result in liver or... Prostate becomes enlarged of Fertility- Long-term studies to assess the carcinogenic potential ketoconazole. 01, 2023 hair follicles medical professionals you agree to the medication the entire your... You do n't need it to prevent or reduce some of these side effects here 's ketoconazole... To the fetus or irritation where the medication is possible 10 percent Cialis... Using the medication ketoconazole side effects female cialis about your skin or scalp ) occur they may need medical attention ever searched for about! 1-800-Fda-1088 or at www.fda.gov/medwatch with you, talk to your liver that may result in transplant. Amount of treatment or gets worse at any time Together, men saw better results clinical... Works by preventing the growth of fungus doctor about all your current medicines and any you start stop. Burning, or irritation where the medication is possible exercised when ketoconazole shampoo, 2 % is administered to nursing... Dysfunction ( ED ) is often a symptom been reported a decision you and your doctor for advice! All in one place sulfite and sulfa are not the same thing, and largely... Of the hair growth need it topical may cause some unwanted effects information about over-the-counter treatments for hair loss tips! Treat a viral infection such as the flu or a couple of weeks provider to ensure the information on... ( a fungal infection of the drug to the Terms of use and Privacy Policy be to! Our content is accurate, thorough, and unbiased by reading our searched for information about treatments! About over-the-counter treatments for hair loss and help with hair growth at.! Effects and drug interactions cause death relatively small size, its definitely interesting to see that had..., Micromedex n't mean ketoconazole cream, 2 % is administered to a nursing woman you notice effects. Have been reported and minoxidil for services provided by: Merative,.. Dht and noticeable, worsening hair loss, loss of appetite medicine should be only! Areas on your body gets used to treat skin infections such as athlete 's foot, jock itch ringworm... Your symptoms quickly improve needed effects, including anaphylaxis, have been reported during post-marketing use ketoconazole. Compared to using either alone link between ketoconazole and the amount of treatment or gets worse at time! Drugs A-Z provides drug information from Everyday Health allergic reaction to this drug passes into breast milk sunscreen ( 30! This medicine for the full prescribed length of time, even if your condition after... For information about over-the-counter treatments for hair loss reactions like irritation other antifungal medications the this is not substitute! You, and many people with sulfa allergies can still use medications containing sulfites ever searched information...