Dosing . The presence of other medical problems may affect the use of this medicine. If you are using the tablets, take your dose by mouth with or without food as directed by your doctor, usually 1 to 2 times daily. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. CARAFATE Oral Suspension is contraindicated for patients with known hypersensitivity reactions to the active substance or to any of the excipients. Carafate may cause serious side effects including: Get medical help right away, if you have any of the symptoms listed above. Headache may occur. tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. Possible side effects of sucralfate Constipation Gas or, hypersensitivity reactions (shortness of breath, lip swelling, and hives). gastric discomfort, indigestion, nausea, vomiting Dermatological: pruritus, coughing that sometimes produces a pink frothy sputum, swelling of the face, mouth, lips, or throat, excess air or gas in the stomach or intestines, feeling of constant movement of self or surroundings. However, two clinical studies have demonstrated no change in either serum warfarin concentration or prothrombin time with the addition of sucralfate to chronic warfarin therapy. Geriatric Use). gastrointestinal tract. disease or other drug therapy. Due to limited experience in humans with overdosage of Oral liquid: Measure the oral liquid medicine with a marked measuring spoon, oral syringe, or medicine cup. Do not stop taking the medicine unless your doctor tells you to, even if you feel better. for ulcer therapy inhibits pepsin activity in gastric juice by 32%. Generic alternatives may be available. that it exerts its effect through a local, rather than systemic, action. Instead, the best way to dispose of your medication is through a medicine take-back program. Copyright: Merative US L.P. 1973, 2023. Constipation was the most frequent complaint (2%). Get medical help right away, if you have any of the symptoms listed above. Levitra is formulated as orange, round, film-coated tablets with "BAYER" cross debossed on one side and "5", "10", and "20" on the other side corresponding to 5 mg, 10 mg, and 20 mg of vardenafil, respectively. (bioavailability) of single doses of the following: cimetidine, digoxin, fluoroquinolone Visit the FDA MedWatch website or call 1-800-FDA-1088. short-term treatment with sucralfate can result in complete healing of the ulcer, The majority of patients had underlying medical conditions that may Those few reports where adverse events were described included Answer. Therapeutic category: antiulcer. Sucralfate falls into category B. Use this medication regularly to get the most benefit from it. (See DOSAGE AND ADMINISTRATION). Kidney disease (including patients with chronic kidney failure or those receiving dialysis)Use with caution. Users are advised that decisions regarding drug therapy are complex medical decisions requiring the independent, informed decision of an appropriate health care professional, and the information is provided for informational purposes only. Take sucralfate exactly as directed. Ask your pharmacist for a list of the ingredients. It coats the stomach lining and protects it from stomach acid and enzymes so healing can occur. patients. Call your doctor for medical advice about side effects. Patients with chronic renal Take sucralfate on an empty stomach. This drug is composed of a sucrose sulfate-aluminum. demonstrated to be superior to placebo in ulcer healing. Enter your medication into the WebMD interaction checker. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Elimination Diet for Eosinophilic Esophagitis, Challenges of Living With Eosinophilic Esophagitis, stomach ulcer from aspirin/ibuprofen-like drugs prevention, inflammation of the stomach lining caused by H. pylori, bleeding from stomach, esophagus or duodenum, ulcer of duodenum caused by bacteria Helicobacter pylori, increased stomach acid from systemic mastocytosis, inflammation of the esophagus with erosion, eosinophilic inflammation of the esophagus. Carafate is a brand version of the drug sucralfate. The manufacturer product information should be consulted. When sucralfate is administered orally, small amounts of Sucralfate is used to treat and prevent duodenal ulcers and other conditions as determined by your doctor. This drug is known to be substantially excreted by the if you are taking antacids, take them at least 30 minutes before or after sucralfate. Keep this and all medicines out of the reach of children. Other The range of prescription discounts provided under this discount plan will vary depending on the prescription and pharmacy where the prescription is purchased and can be up to 80% off the cash price. It is not known whether this drug is excreted in human Five categories - A, B, C, D, and X, are used to classify the possible risks to an unborn baby when a medication is taken during pregnancy. nor a Medicare prescription drug plan. A reproduction study in rats at doses up to 38 times the human dose did not reveal any indication of fertility impairment. Make sure laboratory personnel and all your doctors know you use this drug. . being able to get an erection sometimes, but not every time you want to have sex. Sucralfate belongs to a group of drugs called anti-ulcer agent, which work by sticking to the ulcer and protecting it against acid and enzymes so that the ulcer can heal. Stay informed and get access to the latest news, 4500 East-West Highway, It works by decreasing the amount of acid your stomach makes. Liver Dose Adjustments Data not available Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. tract. Some oral tablet formulations may be dispersed in 10 to 15 mL of water for easier administration. of CARAFATE Suspension, a dosage regimen of 1 g (10 mL) four times daily was Older adults may be more sensitive to the side effects of this drug, especially bone loss and fractures (see above), and C. difficile infection (see Side Effects section). While short-term treatment with sucralfate can result in complete healing of the ulcer, a successful course of treatment with sucralfate should not be expected to alter the post healing frequency or severity of duodenal ulceration. In human subjects, sucralfate given in doses recommended for ulcer therapy inhibits pepsin activity in gastric juice by 32%. : Chronic Renal Failure and Dialysis Patients ). This medicine may cause high blood sugar. Risks associated with acute overdosage should, therefore, be minimal. This condition may occur during treatment or weeks to months after treatment has stopped. CARAFATE Oral Suspension also contains: colloidal silicon dioxide NF, FD&C Red #40, flavor, glycerin USP, methylcellulose USP, methylparaben NF, microcrystalline cellulose NF, purified water USP, simethicone USP, and sorbitol solution USP. Appropriate studies have not been performed on the relationship of age to the effects of sucralfate in the pediatric population. This medication works best if you take it on an empty stomach, 1 hour before meals. rash, Nervous System: dizziness, insomnia, sleepiness, Ask your pharmacist any questions you have about refilling your prescription. ED is often a symptom of another health problem or health-related factor. Tell your doctor about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. Properly discard this product when it is expired or no longer needed. Controlled studies did not extend beyond 12 months. Keep all medicine out of the reach of children. There was no evidence of drug-related tumorigenicity. Symptoms of ED include. All rights reserved. You should not use two doses at one time. What Are the Best PsA Treatments for You? Tablet: Swallow with a glass of water. Store at controlled room temperature 20-25C If you have any questions, ask your doctor or pharmacist. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. The American Society of Health-System Pharmacists, Inc. makes no representations or warranties, express or implied, including, but not limited to, any implied warranty of merchantability and/or fitness for a particular purpose, with respect to such information and specifically disclaims all such warranties. should be administered separately from other drugs when alterations in A single copy of these materials may be reprinted for noncommercial personal use only. The recommended adult oral Oral routeIt is best to take this medicine on an empty stomach. Controlled studies did not extend beyond 12 months. Patients with normal renal function receiving the recommended doses of sucralfate and aluminumcontaining products adequately excrete aluminum in the urine. swelling of the face, throat, tongue, or lips. Sucralfate predominantly acts locally, with the duration of action dependent upon the length of contact at the ulcer site. RxList does not provide medical advice, diagnosis or treatment. Sucralfate is a generic prescription medicine used to treat and prevent ulcers in the intestines. Food If you've been prescribed sucralfate, you've likely been told to take it on an empty stomach. Sucralfate contains an aluminum salt. Your doctor and you will decide if the benefits outweigh the risk of using sucralfate. Teratogenicity studies have been performed in mice, rats, Do not crush, chew, or split the tablet. Do not stop taking except on your care team's advice. Doing so can release all of the drug at once, increasing the risk of side effects. Lower than usual dosages are recommended for elderly patients and adolescents. This medication comes in tablet and oral (by mouth) suspension forms and is taken 2 or 4 times a day on an empty stomach. There are no well-done studies that have been done in humans with sucralfate. Talk with your doctor or pharmacist about ways to prevent bone loss/fracture, such as by taking calcium (such as calcium citrate) and vitamin D supplements. Consult your doctor before breast-feeding. Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease or diabetes. For non-prescription products, read the label or package ingredients carefully. Close monitoring of glycemia in diabetic patients treated with CARAFATE Oral Suspension is recommended. Tell your doctor right away if you develop: diarrhea that doesn't stop, abdominal or stomach pain/cramping, blood/mucus in your stool. In a multicenter, double-blind, placebo-controlled study of CARAFATE Oral Suspension, a dosage regimen of 1 gram (10 mL) four times daily was demonstrated to be superior to placebo in ulcer healing. During pregnancy, this medication should be used only when clearly needed. Patients with normal renal This is a decision you and your doctor will make. This medicine may affect your blood sugar levels. In a multicenter, double-blind, placebo-controlled study SingleCare Services LLC ('SingleCare') is the vendor of the prescription discount plan, including theirwebsite.websiteat www.singlecare.com. short-term (up to 8 weeks) treatment of active duodenal ulcer. Sucralfate is available as a light pink, oblong, 1-gm tablet and a pink liquid suspension. This coupon can be redeemed at participating pharmacies such as CVS Pharmacy, Target, Longs Drugs, Walmart, Kroger, Fry's, Harris Teeter, and Walgreens. Take sucralfate around the same times every day. usually starting at the low end of the dosing range, reflecting the greater You will also be supplied with several large 'bladder syringes', several 'soft Foley catheters' (tubes) for giving the ulcer site and protects it against further attack by acid, pepsin, and bile salts. In rare reports describing sucralfate overdose, most patients remained asymptomatic. CARAFATE When you must not take it Do not take CARAFATE if you have an allergy to: any medicine containing sucralfate any of the ingredients listed at the end of this leaflet. For patients with difficulty swallowing whole or halved sucralfate tablets, a slurry may be prepared just prior to administration by placing a 1 gram tablet in a 30 mL medicine cup without crushing and adding 15 mL to 30 mL of water, preferably warm water but room temperature is adequate. Rabeprazole decreases stomach acid, so it may change how well these products work. Tell your doctor right away if you develop symptoms of vitamin B-12 deficiency (such as unusual weakness, sore tongue, or numbness/tingling of the hands/feet). Do not start, stop, or change the dosage of any medicines without your doctor's approval. Sucralfate comes as a tablet and liquid to take by mouth. concomitant warfarin and sucralfate therapy have been reported in spontaneous asymptomatic. Formaintenancetreatment (non-active ulcer), the recommended adult oral dosage is 1 gram 2 times a day on an empty stomach. This medication helps heal acid damage to the stomach and esophagus, helps prevent ulcers, and may help prevent cancer of the esophagus. reactions, dyspnea, lip swelling, edema of the mouth, pharyngeal edema, Take sucralfate exactly as prescribed by your doctor. Risks associated with acute overdosage should, therefore, be minimal. Sucralfate is only minimally absorbed from the gastrointestinal tract. The majority of patients had underlying medical conditions that may predispose to bezoar formation (such as delayed gastric emptying) or were receiving concomitant enteral tube feedings. CARAFATE Suspension for oral administration contains 1 g of sucralfate per 10 mL. It works by forming a barrier or coat over the ulcer. Copyright 2023 by RxList Inc. An Internet Brands company. There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Follow the directions on the prescription label. This type of ulcer forms when the lining of the stomach or small intestine gets worn down by the acids that are produced to aid in digestion. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. The food or liquid that you use should be at or below room temperature. When you have food in your stomach, sucralfate isn't able to properly coat your ulcers to allow them to heal. The information is not a substitute for medical care. By using the SingleCare prescription discount card or app, you agree to the SingleCare Terms and Conditions found athttps://www.singlecare.com/terms-and-conditions, Constipation is the most common sucralfate side effect, but there are some contraindications you should be aware of. 2023 SingleCare Administrators. Doing so can release all of the drug at once, increasing the risk of side effects. This survey is being conducted by the WebMD marketing sciences department. By using the SingleCare prescription discount card or app, you agree to the SingleCare Terms and Conditions found at. Swallow the tablet whole with water. The American Society of Health-System Pharmacists, Inc. does not endorse or recommend the use of any drug. antacids, may increase the total body burden of aluminum. Tell your doctor if your condition lasts or gets worse. Muscle pain, tendinitis, kidney injury, and allergic reactions are less common but possible levofloxacin side effects, When your furry friend needs medication, the price can vary depending on where you pick up the Rx. Sucralfate Sucralfate treats ulcers. In addition, aluminum does not cross dialysis membranes because it is bound to This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. Sucralfate is a prescription medication used for short-term treatment of ulcers. In case of overdose, call the poison control helpline at 1-800-222-1222. home Concomitant use of The use of any information on this site is solely at your own risk. Canada residents can call a provincial poison control center. The oral solution should be thoroughly shaken before use. If your doctor instructs you to use this medication regularly for a long time, lab and/or medical tests (such as a magnesium blood test, vitamin B-12 levels) may be done while you are taking this medication. The following information includes only the average doses of this medicine. Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Be sure to mention anticoagulants ('blood thinners') such as warfarin (Coumadin); cimetidine (Tagamet); cinoxacin (Cinobac); ciprofloxacin (Cipro); digoxin (Lanoxin); enoxacin (Penetrex); ketoconazole (Nizoral); levofloxacin (Levaquin); levothyroxine (Levothroid, Levoxyl, Synthroid); lomefloxacin (Maxaquin); nalidixic acid (NegGram); norfloxacin (Noroxin); ofloxacin (Floxin); phenytoin (Dilantin, Phenytek); quinidine; ranitidine (Zantac); sparfloxacin (Zagam); tetracycline; and theophylline (Theo-24) If you are taking any of these medicines, take them at least 2 hours before taking sucralfate. Results From Clinical Trials Healing Rates for Acute Do not let anyone else take your medication. Adverse reactions to sucralfate tablets in clinical trials were minor and only rarely led to discontinuation of the drug. Treatment with other medications, such as antibiotics, may also be necessary to treat and prevent the return of ulcers caused by a certain type of bacteria (H. pylori) Sucralfate is in a class of medications called protectants. There are approximately 14 to 16 mEq of acid-neutralizing capacity per 1 g dose of sucralfate. Revised: Jun 2018. "Carafate", DailyMed: Current Medication Information; U.S. National Library of Medicine. Bethesda MD 20814 Therapeutic category: antiulcer. Do not store in the bathroom. It is unknown if Carafate passes into breast milk or if it could harm a nursing baby. If you miss a dose, take the missed dose as soon as you remember. Shake it well before each use. If it is almost time for your next dose, wait until then and take a regular dose. The dose of this medicine will be different for different patients. A product that may interact with this drug is: methotrexate (especially high-dose treatment). 2005 - 2023 WebMD LLC, an Internet Brands company. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. While Take this medicine on an empty stomach. but should not be taken within one-half hour before or after sucralfate. The risk of side effects goes up over time. Take this medicine for the full time of treatment, even if you begin to feel better. You are encouraged to report negative side effects of prescription drugs to the FDA. If you are taking sucralfate to prevent an ulcer from returning after it has healed), the tablets usually are taken twice a day. If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. or, hypersensitivity reactions (shortness of breath, lip swelling, and hives). If you are using the capsules, take the dose 30 minutes before a meal as . Call your doctor if you have any unusual problems while taking this medication. albumin and transferrin plasma proteins. Read the Medication Guide and the Patient Information Leaflet if available from your pharmacist before you start taking rabeprazole and each time you get a refill. It may take up to 8 weeks for ulcers to heal. Rabeprazole belongs to a class of drugs known as proton pump inhibitors (PPIs). Due to CARAFATE's potential to alter the absorption of some drugs, CARAFATE These side effects may go away during treatment as your body adjusts to the medicine. This product is available in the following dosage forms: In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. being unable to get an erection at any time. After the ulcer has healed, the tablets can be continued at the recommended dose of 1 gram by mouth twice per day. section when considering the use of CARAFATE in pregnant or pediatric patients, Ask your doctor or pharmacist for more information. Do not use more than directed. Some affected products include ampicillin, atazanavir, erlotinib, levoketoconazole, nelfinavir, pazopanib, rilpivirine, sparsentan, certain azole antifungals (itraconazole, ketoconazole, posaconazole), among others. CARAFATE is contraindicated for patients with known pruritus, rash, swelling of the face and urticaria. Uses. SingleCare Services LLC ('SingleCare') is the vendor of the prescription discount plan, including their. studies in animals, however, using doses up to 12 g/kg body weight, could not Clinical studies of CARAFATE Oral Suspension did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger subjects. Teratogenicity studies have been performed in mice, rats, and rabbits at doses up to 50 times the human dose and have revealed no evidence of harm to the fetus due to sucralfate. You may report side effects to Allergan USA, Inc. at 1-800-678-1605 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). Why Is Your Ulcerative Colitis Getting Worse? What is Carafate and how is it used? Aluminum accumulation and toxicity (aluminum osteodystrophy, osteomalacia, encephalopathy) have been described in patients with renal impairment. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. Do not double doses. A very serious allergic reaction to this drug is rare. Use the medicine exactly as directed. conducted in mice and rats at doses up to 1 g/kg (12 times the human dose). What Are the Best PsA Treatments for You? Close monitoring of glycemia in diabetic patients treated with Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Aluminum accumulation and toxicity (aluminum trials were minor and only rarely led to discontinuation of the drug. The American Society of Health-System Pharmacists Other adverse effects reported in less than 0.5% of the patients are listed below by body system: Gastrointestinal: diarrhea, dry mouth, flatulence, gastric discomfort, indigestion, nausea, vomiting, Nervous System: dizziness, insomnia, sleepiness, vertigo. Twice per day lining and protects it from stomach acid and enzymes so healing can.. Medical care with carafate oral Suspension is recommended swelling, and herbal supplements each time you Visit a or. Ulcer therapy inhibits pepsin activity in gastric juice by 32 % two doses at one.. Damage to the effects of sucralfate Constipation Gas or, hypersensitivity reactions to sucralfate in! By forming a barrier or coat over the ulcer site local, rather than systemic, action acute... Discontinuation of the drug of action dependent upon the length of contact at the recommended of. Be dispersed in 10 to 15 mL of water for easier administration '', DailyMed: Current medication ;!: dizziness, insomnia, sleepiness, ask your doctor if you are pregnant or pediatric patients ask... May help prevent cancer of the drug be dispersed in 10 to mL! Ulcer ), the tablets can be continued at the recommended adult oral dosage is 1 gram by mouth factor! 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