You may report them to the FDA. I dont know if it helped or not yet.Read More Read Less, Never been in so much joint pain everywhere. How does Reclast work? It does say it is sometimes is used for off-label purposes but osteoporosis sounds like a stretch. Due to a sudden fall and positive bone scan (for osteoporosis), I was convinced to take the Reclast infusion. @lioness. All of this, the migraines, the bone pain, and the muscle pain made sleeping normally impossible. Becky, why did your endocrinologist suggest switching medications? The day after, I experienced fatigue, weakness, chills, headache, and nausea, but today I am feeling good and back to my old self! Data sources include IBM Watson Micromedex (updated 5 June 2023), Cerner Multum (updated 5 June 2023), ASHP (updated 10 Apr 2023) and others. This is especially important if you have cancer, if you are undergoing chemotherapy or using steroids, or if you have poor dental health. Meclizine". Avoid during pregnancy. Today, the endocrinologist suggested that I switch to Reclast for 3 yearly infusions. Arthritis Center News That is my experience with Reclast. Even my thumbs. Reclast is used to treat or prevent osteoporosis caused by menopause, or steroid use. User Reviews for Reclast to treat Osteoporosis. After treatment with Reclast, BMD increased by 11% from baseline after one year of treatment and by 20.7% from baseline after two years of treatment. Available for Android and iOS devices. Osteolytic Bone Lesions of Multiple Myeloma, Osteolytic Bone Metastases of Solid Tumors, Patients must be appropriately hydrated prior to administration of Reclast [. I could not walk. I have acid reflux and indigestion due to the different anti-inflammatory drugs I was taking to offset the pain the Reclast caused me. Now Im having to stop taking the anti-inflammatory drugs, and Im half immobile again. At the 7 month point my teeth were so painful I went to dentist for X-rays and to check if jaw deterioration. I also have had problems with some PPIs and with a medication that I was given prior to transplant that that made me sick for two days. I took Reclast 2 months ago and so far so good. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Instruct patients being treated for osteoporosis to take supplemental calcium and vitamin D if their dietary intake is inadequate. One study found that Reclast, or zoledronic acid, given through injection once a year, may actually work even better. Osteolytic Bone Lesions of Multiple Myeloma, Osteolytic Bone Metastases of Solid Tumors. The American Bone Health Fracture Risk Calculator estimates fracture risk for women and men over age 45. You are at risk for osteoporosis if you are: Zolendronic acid is given as an infusion (through a vein in your arm) lasting 15 minutes. I took the reclast to prevent spinal fractures after stopping Prolia (based on MD advise). Other conditions associated with osteonecrosis of the jaw include blood clotting disorders, anemia (low red blood cells), and pre-existing dental problems. There are no data on fetal risk and pregnancy in humans. I felt perfect for the remainder of the day after the infusion. Cialis is often called the "weekend pill" as it's effects can last up to 36 hours, meaning your sex life can have a certain amount of sponteneity not possible with other erectile dysfunction drugs. Calcium and vitamin D supplementation: 1. I also began to take Claritin on Sunday. My actual infusion took about an hour: 15 min of the Reclast and then 30 min of a saline drip. Get emergency medical help if you have signs of an allergic reaction to Reclast: hives; wheezing, chest tightness, trouble breathing; swelling of your face, lips, tongue, or throat. I have no idea if the Reclast was effective, and I wont know until my next bone scan, but PLEASE DONT ASSUME YOU WILL NEGATIVELY REACT. I did not have one side effect from the Reclast infusion. You should drink 2 glasses of fluid at least one hour before receiving your infusion. I will post an update if anything changes, but as of right now, this medication was horrible. Comments: Retreatment may be considered in patients who have relapsed, based on increases in serum alkaline phosphatase or failure to achieve normalization of serum alkaline phosphatase. Read More Read Less. Now, Im still experiencing constant side effects. If yes, how long did it last? Medications That Can Be Bad for Your Bones, Tests to Determine Secondary Causes of Bone Loss, American Bone Health and Susan G. Komen Team Up for Healthy Living Campaign, How cancer patients can lower the risk of bisphosphonate-related osteonecrosis of the jaw (BRONJ), What we know about vitamin D and bone health, American Bone Health calls on Americans to know their risk factors and take action to prevent falls and broken bones during Falls Prevention Awareness Week, Understanding How Obesity Affects Bone Health and Risk of Fractures, American Bone Health calls on American to Build Better Bones during National Osteoporosis Month 2022. The following day (yesterday), my lower back, hips, and upper legs hurt. I want to make people aware that this can happen. In addition to this, my neck and back hurt constantly as well. Two years ago I was diagnosed with pretty bad osteoporosis because of the prednisone I was on for my autoimmune disease. The UK is the first country to allow OTC access to Sanofi's tadalafil-based erectile dysfunction drug Cialis following a successful switch. Reclast can cause serious kidney problems, especially if you are dehydrated, if you take diuretic medicine, or if you already have kidney disease. The most common side effects with the pill are diarrhea, pain in the extremities, and upset stomach. As it is I am exercising, doing weight-bearing exercises along with others, (balance, core, cardio), taking calcium, vitamins D and K. I am scared to death about the medications though. Comments: An average of at least 1200 mg calcium and 800 to 1000 international units vitamin D daily is recommended. Pharmaceutical Society of Australia "APPGuide online. Flu-like syndromes including fever, chills, bone pain, and/or arthralgias and myalgias have also occasionally been reported. prednisone, hydrochlorothiazide, alendronate, dexamethasone, estradiol, Prolia, Fosamax, calcium carbonate, Decadron, denosumab. I think its getting better but I really think my health care providers could have prepared me to know to drink a lot prior to the. Muscle and joint pain has been persistent 1 year later. Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit. I will never take this medication again. Call your doctor for instructions if you miss an appointment for your Reclast injection. Some side effects may not be reported. It started out as flu like symptoms then advanced to full on body pain. but I believe degraded physical state due to reclast as I have had no other changes. I did water aerobics and recumbent road Trike 5 days a week but I believe degraded physical state due to reclast as I have had no other changes. The risk is highest in people with cancer, blood cell disorders, pre-existing dental problems, or people treated with steroids, chemotherapy, or radiation. Cerner Multum, Inc. "UK Summary of Product Characteristics." The flu like symptoms generally disappears after 24-48 hours and usually occurs only after the first injection. Middle of third day symptoms subsided except unrelenting headache which has gotten progressively worse to migraine degree (without aura) everyday for 10 days now. Ibandronate has a high affinity for hydroxyapatite, which is part of the mineral matrix of bone. [Ref], Very common (10% or more): Fever (44.2%), moniliasis (11.6%), Common (1% to 10%): Nonspecific infections, asthenia, mucositis, chest pain, leg edema, Postmarketing reports: Flu-like syndrome, pyrexia, fatigue, malaise; osteonecrosis of the external auditory canal have been reported predominantly in cancer patients treated with intravenous bisphosphonates (many of these patients were also receiving chemotherapy and corticosteroids which may be a risk factor for ONJ). The primary side effect is drowsiness. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Last updated on Jul 7, 2022. Reclast is used to treat or prevent osteoporosis caused by menopause, or steroid use. convulsions cough depression difficult or labored breathing dizziness dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position fever irregular heartbeat Reclast is also used to treat Paget's disease of bone. Reclast has an average rating of 5.1 out of 10 from a total of 159 reviews for the treatment of Osteoporosis. After those 5 weeks, the headaches began slowly resolving, but my back, shoulders, and neck continued to hurt for several more weeks. A lowering in the levels of certain electrolytes such as phosphate, potassium, and magnesium may occur. Rarely patients have reported severe bone, joint and muscle pain that begins from 1 day to one month after starting any bisphosphonate, including Zolendronic acid. I had to be on migraine medicine almost non-stop for months (approximately every 3 hours). The effectiveness of Reclast is comparable to most other bisphosphonates; however, because it has a very favorable dosing regimen, people prefer it because it does not have to be taken as often as some other bisphosphates. Reclast is working for me both as an easier application, once a year, and better health. Tell your doctor if you experience any thigh or groin pain, muscle cramps or twitches, severe or debilitating muscle pain, eye inflammation, or any other adverse effects of concern while you are being administered Reclast. -Prevention of glucocorticoid-induced osteoporosis in men and women who are either initiating or continuing systemic glucocorticoids in a daily dosage equivalent to 7.5 mg or greater of prednisone and are expected to remain on glucocorticoids for at least 12 months. Zometa (zoledronic acid)." Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. . I just had my first Reclast infusion after being on Prolia injections x 3 years. Muscle and joint pain has been persistent 1 year later. Easily managed with continued Tylenol, but I did sleep much of the day. The only apparent side effect of Reclast is a minor flu-type feeling that some patients experience after 48 hours of the injection. Severe jaw bone problems (osteonecrosis). Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. I will never take this medication again. nausea, vomiting, diarrhea, constipation; This is not a complete list of side effects and others may occur. To decrease the chance of stomach upset, this drug is best taken with food. Cialis Together 10mg Tablets - Tadalafil - 4 Tablets. Smoking can reduce your bone mineral density, making fractures more likely. Approved as a pharmacy medicine, Sanofi will launch Cialis Together in the second half of the year. The overall incidence of all atrial fibrillation adverse events in the zoledronic acid treatment group was, reported in 2.5% of patients (96 out of 3862) in the Reclast group vs. 1.9% of patients (75 out of 3852) in the placebo group. Glad I am left handed, but still difficult to have one arm in such pain all the time. Wouldnt recommend to anyone. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Today, two days after procedure, I am normal. I had to go have my rings cut off today because of the pain and swelling. Dosage. In other words.you have 2 years of taking nothing until the new bone begins to age. I plan to continue to hydrate and take the Claritin. Im now on my 7th month of daily pain, pain that wasnt present prior to taking the Reclast. These side effects may go away during treatment as your body adjusts to the medicine. Acute phase reactions have occurred within three days after administration of this drug with symptoms of pyrexia, fatigue, bone pain and/or arthralgias, myalgias, chills, and influenza-like illness. RECLAST INFUSION WAS GOOD. . 2005 - 2023 WebMD LLC, an Internet Brands company. Severe jaw bone problems may happen when you take Reclast. Within 10 hours of infusion I had paralyzing agonizing pain through my body. It is given slowly into a vein over at least 15 minutes. Dose form. Osteolytic Bone Lesions of Multiple Myeloma, Osteolytic Bone Metastases of Solid Tumors. I began to drink more water and sports drinks on Sunday to ensure I was well hydrated. The next day my entire hands and one foot was the same. My actual infusion took about an hour: 15 min of the Reclast and then 30 min of a saline drip. Connect with thousands of patients and caregivers for support, practical information, and answers. I self medicated with high level drugs for 3 weeks. olled now, but pains in my neck, legs, and now my right arm. After reading a lot of reviews, I did the following to prepare: I took a Claritin the day before my procedure, the day of, and will continue for three days after. Now, Im still experiencing constant side effects. Havent had a scan yet so unsure of efficacy in treatment of osteopenia. 37% of reviewers reported a positive experience, while 43% reported a negative experience. Keeping ice on head all day praying for relief. You may report side effects to FDA at 1-800-FDA-1088. Two days ago, I went for my first Reclast infusion. Symptoms of this condition may include jaw pain, swelling, numbness, loose teeth, gum infection, or slow healing after injury or surgery involving the gums. Thanks. Many of these patients had signs of local infection including osteomyelitis, and the majority of the reports refer to cancer patients following tooth extractions or other dental surgeries. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Reclast (sometimes called zoledronate) is a bisphosphonate medicine that alters bone formation and breakdown in the body. | August 19, 2008. After opening, the solution is stable for 24 hours at 2C to 8C (36F to 46F) [see How Supplied/Storage and Handling (16)]. 12-24 hours after reclast infusion I had a severe systemic adverse reaction including vomiting, painful joints and muscles, dizziness and a non infectious biofilm/ granuloma formed on my left lower peri orbital region in my soft tissue under my eye! The dosage is based on your. Millions of Americans take bisphosphonates by mouth to prevent bone loss from osteoporosis or steroid medications, most often once a week or once a month. Uses: I am having so much trouble making that appointment though that I'm getting paranoid! All patients should take 1500 mg elemental calcium daily in divided doses (750 mg two times a day, or 500 mg three times a day) and 800 international units vitamin D daily, particularly in the 2 weeks following Reclast administration [. I used to be very active for my age, but the Reclast made me borderline immobile. The risk of osteonecrosis of the jaw is greater in those who have received chemotherapy, radiation, or steroids. Take this medication by mouth as directed by your doctor, usually once or twice daily. Reclast belongs to the class of medicines known as bisphosphonates. Common side effects of Reclast include: hypophosphatemia, hypokalemia, and hypomagnesemia. Is this normal ?? Apparently, there is a limited period of time in which patients can safely receive this specific treatment. In rare cases some patients have experienced jaw problems when taking bisphosphonates including Zolendronic acid. I will look for other alternatives for osteoporosis treatment. I started a 102-103 degree fever for 2.5 days and still have a low grade fever 9 days later. I took 8 hr release for arthritis-650 mg. I HOPE THIS EASES THE MINDS OF THOSE OF YOU WHO HAVE READ ALL THE NEGATIVE REVIEWS, AND ARE HESITANT TO GO FORWARD WITH RECLAST.Read More Read Less. 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