Females who are able to become pregnant should use effective birth control (contraceptive) during treatment with exemastane and for 1 month after your last dose of exemastane. Inform your doctor right away if your condition worsens (such as you get new breast lumps). Find Clinical Trials for Exemestane - Check for trials from NCI's list of cancer clinical trials now accepting patients. Since this drug can be absorbed through the skin and lungs, women who are pregnant or who may become pregnant should not handle this medication or breathe the dust from the tablets. You should always consult your doctor or another healthcare professional before taking any medication. nabp.pharmacy/programs/accreditations-inspections/digital-pharmacy/accredited-digital-pharmacies/, accessdata.fda.gov/drugsatfda_docs/label/2018/020753s020lbl.pdf, cancer.org/cancer/breast-cancer/risk-and-prevention/aromatase-inhibitors-for-lowering-breast-cancer-risk.html, dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=88fb6543-383b-4195-a2c1-2673ac194f4b, fda.gov/drugs/besaferx-your-source-online-pharmacy-information/know-your-online-pharmacy, What You Need to Know About Breast Cancer in Teens, Yes, Screening for Breast Cancer at 40 Makes Sense, But We Can Do More. Keep a list of all your medications with you, and share this information with your doctor and pharmacist. Exemestane is a hormone therapy drug used to treat breast cancer in women who have gone through a natural menopause (when periods stop). All Rights Reserved. Talk with your doctor or pharmacist, who can provide personalized guidance about cost issues related to you and exemestane. Store it at room temperature and away from excess heat and moisture (not in the bathroom). tell your doctor if you are breastfeeding. at the National Institutes of Health, An official website of the United States government, Drugs Approved for Different Types of Cancer, Drugs Approved for Conditions Related to Cancer, Complementary & Alternative Medicine (CAM), U.S. Department of Health and Human Services. Select a condition to view a list of medication options. This prevents aromatase from converting androgens into estrogen and cuts of the supply of estrogen that the breast cancer cells need to grow. If it is near the time of the next dose, skip the missed dose. Do not take Aromasin if you are allergic to exemestane or any ingredients contained in this drug. What Are the Signs of Inflammatory Breast Cancer? are switching to exemastane to complete 5 years in a row of hormonal therapy. Tell your doctor if you are breastfeeding or plan to breastfeed. This medication is also used to treat breast cancer in . Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins and herbal supplements. It irreversibly binds to the active site of . Do not store in the bathroom. Ingredients vardenafil Print Vardenafil (Ingredient) Chemical formula: C23H32N6O4S Drugbank ID: DB00862 ATC code: G04BE09 The information below refers to products available in the United States that contain vardenafil. Brand names: Aromasin Reviewed by Medicine.com on February 25, 2020 Consumer Health Professional Uses Before taking How to take Side effects Images Storage What is exemestane used for? The original substance accounts for only 1% of excretion in the urine. But exemestane costs significantly less than other breast cancer treatments, such as Kisqali or Ibrance. Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once. Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. . While there are plenty of legitimate pharmacies online, many that operate globally sell counterfeit, expired, or tainted drugs. Advise females of reproductive potential to use effective contraception during treatment and for 1 month after final dose. Tell your doctor if you are pregnant or plan to become pregnant. Available for Android and iOS devices. Brand name: AromasinDrug classes: aromatase inhibitors, hormones/antineoplastics. Do not try to make up the missed dose. Aromasin vs Femara - how do they compare? Take your next dose at the regular time. Bone loss. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. Consult your doctor for more details. All rights reserved. tell your doctor if you have or have ever had osteoporosis (condition in which the bones are fragile and break easily), liver or kidney disease. Exemestane (Oral Route) Print. You can also check the National Association of Boards of Pharmacy website for accredited digital pharmacies. Dosage is based on your medical condition, response to treatment, and other medications you may be taking. [11], A study conducted on young adult males found that the estrogen suppression rate for exemestane varied from 35% for estradiol (E2) to 70% for estrone (E1). What resources are available to help with exemestane cost? Pick the price that's right for you. You should always consult your doctor or another healthcare professional before taking any medication. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location one that is up and away and out of their sight and reach. The drug also counteracts gynecomastia as well as fat and water retention following excessive aromatase production due to testosterone doping. Store at room temperature away from light and moisture. It is also important information to carry with you in case of emergencies. If your doctor has directed you to use this medication, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. You may be able to lower your annual cost of the drug in the following ways: Exemestane comes in a brand-name version called Aromasin. They may also be called estrogen-responsive, hormonally-responsive, or hormone-receptor-positive. As a result, you may want to find out more about this drug. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Exemastane is used in women who are past menopause for the treatment of: It is not known if exemastane is safe and effective in children. Breckenridge Pharmaceuticals exemestane tablets: colloidal silicon dioxide, crospovidone, hydroxypropyl methylcellulose, magnesium stearate, mannitol, microcrystalline cellulose, polysorbate 80, sodium starch glycolate. What Are Side Effects Associated with Using Exemestane? Follow the directions on the prescription label. This medicine is available only with your doctor's prescription. Some breast cancers require estrogen to grow. Talk to your doctor if you are using marijuana (cannabis). Call your doctor for medical advice about side effects. AHFS Patient Medication Information. Dosage form: oral tablet Vardenafil is FDA approved to treat erectile dysfunction (ED). In the US - Call your doctor for medical advice about side effects. Exemestane is often given to women whose cancer has progressed even after taking tamoxifen (Nolvadex, Soltamox) for 2 to 3 years. Drug classes: Aromatase inhibitors, Hormones / antineoplastics. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Discover which breast changes you should report to a doctor, treatment, outlook, and more. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. As a result, the amount of estrogen that the tumor is exposed to is reduced, which will limit the growth of the tumor. Highest blood plasma concentrations are reached after 1.2 hours in breast cancer patients and after 2.9 hours in healthy subjects. Exemestane is an antineoplastic (anticancer) agent used to treat breast cancer in postmenopausal women. Information is also available online at https://www.poisonhelp.org/help. Keep reading to discover several ways to reduce long-term drug costs with exemestane. Exemastane should not be taken with medicines that contain estrogen as they could affect how well exemastane works. Take the missed dose as soon as you remember it. NOTE: This medicine is only for you. The generic is considered to be just as safe and effective . While the CYP3A4 inhibitor ketoconazole had no significant effect on exemestane levels in a clinical trial, the strong CYP3A4 inductor rifampicin significantly cut exemenstane levels about in half (AUC 54%, Cmax 41% for a single dose), potentially compromising its effectiveness. Sections. It is usually used in women who have already received a cancer medication called tamoxifen. Taking exemastane during pregnancy or within 1 month of becoming pregnant can harm your unborn baby. Keep all appointments with your doctor and the laboratory. * In this article, we use the term female to refer to a persons sex assigned at birth. Properly discard this product when it is expired or no longer needed. They can help determine the annual and retail cost of exemestane, including the 25-milligram (mg) strength. Concerned about a red bump on your breast that looks like a pimple? Those cancers have estrogen receptors (ERs), and are called ER-positive. To find out how the cost of Aromasin compares with the cost of exemestane, talk with your doctor, pharmacist, or insurance provider. Premenopausal women who receive ovarian suppression may now benefit from an aromatase inhibitor, a class of drugs that until now has been recommended only for postmenopausal women. tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, and nutritional supplements you are taking or plan to take. $ 161.34. Exemestane has no known severe interactions with other drugs. Find everything you need to know about Exemestane (Aromasin), including what it is used for, warnings, reviews, side effects, and interactions. And generics tend to cost less than brand-name drugs. There is a potential for serious side effects to an unborn child. Do not let anyone else take your medication. Use of the term female in this article refers to sex assigned at birth. If you miss a dose, take it as soon as you remember. Exemestane is used in postmenopausal women who have already been treated with tamoxifen citrate. Drug interactions may change how your medications work or increase your risk for serious side effects. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. They need to know if you have any of these conditions: an unusual or allergic reaction to exemestane, other medicines, foods, dyes, or preservatives. 5 WARNINGS AND PRECAUTIONS 5.1 Reductions in Bone Mineral Density (BMD) Two such organizations are: These sites can provide details about drug assistance programs, ways to make the most of your insurance coverage, and links to savings cards and other services. Chemical formula: C20H24O2Drugbank ID: DB00990ATC code: L02BG06. A generic drug is an exact copy of the active drug in a brand-name medication. Exemestane is also being studied in the treatment of other types of cancer. National Library of Medicine Breckenridge Pharmaceuticals Exemestane Product Label, National Library of Medicine Alvogen Exemestane Product Label, National Library of Medicine Aromasin Product Label. To find out how the costs of Aromasin and exemestane compare, talk with your doctor, pharmacist, or insurance provider. They may have a preference for one version or the other. Healthline Media does not provide medical advice, diagnosis, or treatment. Exemestane comes as a tablet to take by mouth. This page contains brief information about exemestane and a collection of links to more information about the use of this drug, research results, and ongoing clinical trials. Aromasin brand tablets: mannitol, crospovidone, polysorbate 80, hypromellose, colloidal silicon dioxide, microcrystalline cellulose, sodium starch glycolate, magnesium stearate, simethicone, polyethylene glycol 6000, sucrose, magnesium carbonate, titanium dioxide, methylparaben, and polyvinyl alcohol. Store exemastane at room temperature 68F to 77F (20C to 25C). Because of the possible risk to the infant, breast-feeding is not recommended while using this drug and for 1 month after stopping treatment. But if you have health insurance, youll need to talk with your insurance provider to learn the actual cost youll pay for exemestane. Visit your doctor or health care professional for regular checks on your progress. Exemestane (Oral Route) Print. Exemestane is also sometimes used to treat a certain type of breast cancer in women who not yet experienced menopause. It is usually used in women who have already received a cancer medication called tamoxifen. Do not take your medicine more often than directed. Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional. Erectile dysfunction (ED) is often a symptom . By being structurally similar to enzyme targets, exemestane permanently binds to the enzymes, preventing them from converting androgen into estrogen. [7][8], An occasional decrease in lymphocytes has been observed in approximately 20% of patients receiving Aromasin, particularly in patients with pre-existing lymphopenia. 13 Foods That Could Lower Your Risk of Cancer. Advertising on our site helps support our mission. If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. What Are Warnings and Precautions for Exemestane? leg or arm swelling. This medication is also used to treat breast cancer in women who have experienced menopause whose breast cancer has worsened while they were taking tamoxifen. Some breast cancers are made to grow faster by a natural hormone called estrogen. To use the sharing features on this page, please enable JavaScript. This drug may make you dizzy or tired. Any circulating estrogen in post-menopausal women as well as men is the result of estrogen escaping local metabolism and entering the circulatory system. But if you are breastfeeding or plan to take by mouth certain that all information is factually correct,,! Work or increase your risk of cancer androgen into estrogen approvals, alerts and updates skip the missed dose soon! 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