Monitor for potential adverse effects such as nausea, irregular uterine bleeding, breast tenderness and headache. Most Use Caution/Monitor. amiodarone will increase the level or effect of dienogest/estradiol valerate by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Combination oral contraceptives have been shown to significantly decrease plasma concentrations of lamotrigine, likely due to induction of lamotrigine glucuronidation. Use Caution/Monitor. Low risk of contraceptive failure. Advise women to use nonhormonal contraceptives during treatment with elagolix and for 1 week after discontinuing elagolix. Estradiol valerate/dienogest should not be used for at least 28 days after discontinuation of the inducer due to possibility of decreased contraceptive efficacy. Encorafenib can cause fetal harm. Take one active pill (with hormones) once daily for 26 days in a row. Low risk of contraceptive failure. provider for the most current information. Back-up contraception should be continued for 28 days after discontinuing medication to ensure contraceptive reliability. Applies only to oral forms of hormone. [13][57] It is notably not available as a standalone medication in the United States or the United Kingdom. quinidine will increase the level or effect of dienogest/estradiol valerate by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. Talk to your pediatrician regarding the use of this medicine in children. Use Caution/Monitor. Monitor Closely (1)armodafinil will decrease the level or effect of dienogest/estradiol valerate by affecting hepatic/intestinal enzyme CYP3A4 metabolism. bosentan will decrease the level or effect of dienogest/estradiol valerate by affecting hepatic/intestinal enzyme CYP3A4 metabolism. [56] The first product on the market to contain dienogest was a combined birth control pill (with ethinylestradiol), Valette, introduced in 1995 and made by Jenapharm. Low risk of contraceptive failure. [35], In safety studies, dienogest has been assessed in women with endometriosis at high doses of as much as 20mg/day for up to 24weeks and produced no clinically relevant effects on lipid metabolism, liver enzymes, the coagulatory system, or thyroid metabolism. If you are switching from a birth control injection, start taking dienogest and estradiol on the day you would have received your next scheduled injection. commonly, these are generic drugs. Estradiol valerate/dienogest should not be used for at least 28 days after discontinuation of the inducer due to possibility of decreased contraceptive efficacy. prednisone will decrease the level or effect of dienogest/estradiol valerate by affecting hepatic/intestinal enzyme CYP3A4 metabolism. The hormones in dienogest and estradiol can pass into breast milk and may harm a nursing baby. Use Caution/Monitor. Monitor for potential adverse effects such as nausea, irregular uterine bleeding, breast tenderness and headache. Use Caution/Monitor. cefoxitin will decrease the level or effect of dienogest/estradiol valerate by altering intestinal flora. Monitor Closely (1)cephalexin will decrease the level or effect of dienogest/estradiol valerate by altering intestinal flora. The risk of these serious problems increases with age and with the number of cigarettes you smoke. This medicine is also used to treat heavy menstruation (monthly periods) in women who also want to prevent pregnancy. Serious - Use Alternative (1)mobocertinib will decrease the level or effect of dienogest/estradiol valerate by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. Low risk of contraceptive failure. Use Caution/Monitor. An alternate or additional form of birth control may be advisable during concomitant use. The duration generally varies if you are being treated for endometriosis or if it is being given in combination as oral birth control pills. No back up birth control is needed. Avoid tanning booths and sunlamps. Estradiol valerate/dienogest should not be used for at least 28 days after discontinuation of the inducer due to possibility of decreased contraceptive efficacy. Monitor Closely (2)erythromycin base will increase the level or effect of dienogest/estradiol valerate by affecting hepatic/intestinal enzyme CYP3A4 metabolism. cefixime will decrease the level or effect of dienogest/estradiol valerate by altering intestinal flora. Back-up contraception should be continued for 28 days after discontinuing medication to ensure contraceptive reliability. Contraindicated. Monitor Closely (1)cefditoren will decrease the level or effect of dienogest/estradiol valerate by altering intestinal flora. Coadministration of encorafenib with hormonal contraceptives (CYP3A4 substrates) can result in decreased concentrations and loss of hormonal contraceptive efficacy. Significant changes (increase or decrease) in plasma levels of estrogen and progestin have been seen when HIV protease inhibitors are administered. Based on the mechanism of action of elagolix, estrogen-containing contraceptives are expected to reduce elagolix efficacy. Estrogens and progesterones may impair glucose tolerance. Back-up contraception should be continued for 28 days after discontinuing medication to ensure contraceptive reliability. Advise women to use alternative method of contraception or back-up method when moderate or weak enzyme inducer is used with combination contraceptives. Use Caution/Monitor. Use Caution/Monitor. cefprozil will decrease the level or effect of dienogest/estradiol valerate by altering intestinal flora. calaspargase pegol, dienogest/estradiol valerate. nafcillin will decrease the level or effect of dienogest/estradiol valerate by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Applies only to oral forms of hormone. Mechanism of action. Monitor Closely (1)cefotaxime will decrease the level or effect of dienogest/estradiol valerate by altering intestinal flora. Use Caution/Monitor. If you notice other effects not listed above, contact your doctor or pharmacist.In the US -Call your doctor for medical advice about side effects. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Low risk of contraceptive failure. [48][22] It is also unique among most 19-nortestosterone progestins in that it has a double bond between the C9 and C10 positions. Monitor Closely (1)ketoconazole will increase the level or effect of dienogest/estradiol valerate by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use another non-oral contraceptive method for females of childbearing potential. An alternate or additional form of birth control may be advisable during concomitant use. Effects of progestin-only contraceptives on the efficacy of elagolix is unknown. Advise women to use additional or alternative non-hormonal birth control when concomitantly using cenobamate with oral contraceptives. Low risk of contraceptive failure. enasidenib, dienogest/estradiol valerate. Monitor for potential adverse effects such as nausea, irregular uterine bleeding, breast tenderness and headache. Dienogest is not intended to be used as birth control. Smoking can greatly increase your risk of blood clots, stroke, or heart attack. Low risk of contraceptive failure. Use Caution/Monitor. Use Caution/Monitor. After you have taken the last active pill, take one reminder pill once daily for 2 days in a row unless otherwise directed by your doctor. aztreonam will decrease the level or effect of dienogest/estradiol valerate by altering intestinal flora. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. Modify Therapy/Monitor Closely. Monitor Closely (1)amiodarone will increase the level or effect of dienogest/estradiol valerate by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Advise women to use alternative method of contraception or back-up method when moderate or weak enzyme inducer is used with combination contraceptives. Do not start, stop, or change the dosage of any medicines without your doctor's approval. Use Caution/Monitor. Use Caution/Monitor. Monitor Closely (1)cefuroxime will decrease the level or effect of dienogest/estradiol valerate by altering intestinal flora. Do not skip any doses. An alternate or additional form of birth control may be advisable during concomitant use. Other (see comment). Backup contraceptive method recommended. You should not take this medicine if you smoke and are over 35 years old. Do not use this medicine if you are pregnant or if you have recently had a baby. Applies only to oral forms of hormone. Women should not choose estradiol valerate/dienogest as their contraceptive while using strong CYP3A4 inducers due to potential decrease in contraceptive efficacy. If you are switching from another birth control pill, start taking dienogest and estradiol on the first day of your period. dienogest/estradiol valerate will decrease the level or effect of lonapegsomatropin by Other (see comment). Monitor Closely (1)azithromycin will decrease the level or effect of dienogest/estradiol valerate by altering intestinal flora. Use Caution/Monitor. Monitor for potential adverse effects such as nausea, irregular uterine bleeding, breast tenderness and headache. Applies only to oral forms of hormone. View the formulary and any restrictions for each plan. Your risk increases the older you are and the more you smoke. Use Caution/Monitor. [13][57], Dienogest has been studied as a form of male hormonal contraception. A lot of people also use it in conjunction with an IUD for birth control purposes. dienogest/estradiol valerate decreases effects of metformin by pharmacodynamic antagonism. Serious - Use Alternative (1)lesinurad decreases effects of dienogest/estradiol valerate by affecting hepatic/intestinal enzyme CYP3A4 metabolism. If an oral contraceptive is taken on the same day of sugammadex, or the patient has a transdermal or implant hormonal contraceptive, the patient must use an additional, nonhormonal contraceptive method or back-up method of contraception (eg, condoms and spermicides) for the next 7 days. Advise women of childbearing potential to use a highly effective nonhormonal contraceptive during treatment and for 2 weeks after final encorafenib dose. Use Caution/Monitor. Use Caution/Monitor. Applies only to oral forms of hormone. Monitor for potential adverse effects such as nausea, irregular uterine bleeding, breast tenderness and headache. You may choose to take this medication at another time of day that is easier for you to remember. Use Caution/Monitor. Use Caution/Monitor. C[C@]12CCC3=C4CCC(=O)C=C4CC[C@H]3[C@@H]1CC[C@]2(CC#N)O, InChI=1S/C20H25NO2/c1-19-8-6-16-15-5-3-14(22)12-13(15)2-4-17(16)18(19)7-9-20(19,23)10-11-21/h12,17-18,23H,2-10H2,1H3/t17-,18+,19+,20-/m1/s1, progesterone receptor membrane component-1, List of progestogens available in the United States, "Pharmacology of estrogens and progestogens: influence of different routes of administration", "Progestogens in menopausal hormone therapy", "TGA eBS - Product and Consumer Medicine Information Licence", "Dienogest - Bayer HealthCare Pharmaceuticals/Mochida Pharmaceutical - AdisInsight", "Gynaecological uses of dienogest alone and in combination with oestrogens", "Antiandrogenic and antimineralocorticoid health benefits of COC containing newer progestogens: dienogest and drospirenone", "Review of the safety, efficacy and patient acceptability of the combined dienogest/estradiol valerate contraceptive pill", "Fertility after discontinuation of treatment with an oral contraceptive containing 30 microg of ethinyl estradiol and 2 mg of dienogest", "An overview of the development of combined oral contraceptives containing estradiol: focus on estradiol valerate/dienogest", "Dienogest for the treatment of endometriosis", "Visanne, tablets, 2 mg Bayer BV, The Netherlands (dienogest)", "Venous thrombosis and hormonal contraception: what's new with estradiol-based hormonal contraceptives? Copyright 1996-2023 Cerner Multum, Inc. mifepristone will increase the level or effect of dienogest/estradiol valerate by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Brushing and flossing your teeth regularly may help limit this. mavacamten will decrease the level or effect of dienogest/estradiol valerate by affecting hepatic/intestinal enzyme CYP3A4 metabolism. If you have just given birth or had a pregnancy loss/abortion after the first 3 months, talk with your doctor about reliable forms of birth control, and find out when it is safe to start using birth control that contains a form of estrogen, such as this medication.This medication may decrease breast milk production. Avoid or Use Alternate Drug. It is used to treat pelvic pain caused by endometriosis. [47][13] It is also known by its synonyms dienogestril and cyanomethyldienolone as well as by its numerous former developmental code names including BAY 86-5258, M-18575, MJR-35, SH-660, SH-T00660AA, STS-557, and ZK-37659. Your list will be saved and can be edited at any time. [13][11] It is taken by mouth. Do not take your medicine more often than directed. Monitor for potential adverse effects such as nausea, irregular uterine bleeding, breast tenderness and headache. Based on the mechanism of action of elagolix, estrogen-containing contraceptives are expected to reduce elagolix efficacy. Women should not choose estradiol valerate/dienogest as their contraceptive while using strong CYP3A4 inducers due to potential decrease in contraceptive efficacy. You may report side effects to FDA at 1-800-FDA-1088. Use Caution/Monitor. Pregnancy is more likely if you miss pills, start a new pack late, or take your pill 12 hours later than the usual time.If you have vomiting or diarrhea within 3 to 4 hours after taking your tablet, read the Patient Information Leaflet section titled "What to Do if You Miss Tablets." [23], Dienogest is used primarily in birth control pills in combination with ethinylestradiol under the brand name Valette. Monitor Closely (1)aztreonam will decrease the level or effect of dienogest/estradiol valerate by altering intestinal flora. It works by stopping a woman's egg from fully developing each month. Contraindicated (1)eslicarbazepine acetate will decrease the level or effect of dienogest/estradiol valerate by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Low risk of contraceptive failure. Use Caution/Monitor. Also tell your doctor if you have any new spotting or breakthrough bleeding, because these may be signs that your birth control is not working well. Avoid or Use Alternate Drug. Contraindicated. Use Caution/Monitor. Taking this medication after your evening meal or at bedtime may help if you have stomach upset or nausea with the medication. Consult your pharmacist or local waste disposal company. Advise women to use alternative method of contraception or back-up method when moderate or weak enzyme inducer is used with combination contraceptives. Copyright 2023 Elsevier Inc. All Rights Reserved. Monitor Closely (1)ampicillin will decrease the level or effect of dienogest/estradiol valerate by altering intestinal flora. Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature. [29], Birth control pills containing dienogest and estradiol valerate are approved in the United States for the treatment of menorrhagia (heavy menstrual bleeding). Minor/Significance Unknown. Get medical help right away if you have: shortness of breath/rapid breathing, chest/jaw/left arm pain, unusual sweating, confusion, sudden dizziness/fainting, pain/swelling/warmth in the groin/calf, sudden/severe headaches, trouble speaking, weakness on one side of the body, sudden vision changes.A very serious allergic reaction to this drug is rare. Then take one pill per day in the order directed on the pack. This combination hormone medication is used to prevent pregnancy. Applies only to oral forms of hormone. [20], Dienogest is the generic name of the drug and its INN, USAN, BAN, and JAN, while dinogest is its DCF. Omaveloxolone may reduce efficacy of hormonal contraceptives (eg, pill, patch, ring), implants, and progestin-only pills owing to weak CYP3A4 induction. Use Caution/Monitor. Women should not choose estradiol valerate/dienogest as their contraceptive while using strong CYP3A4 inducers due to potential decrease in contraceptive efficacy. Avoid coadministration unless benefit outweighs risk. Do not use if you are pregnant. An alternate or additional form of birth control may be advisable during concomitant use. Monitor Closely (1)dasatinib will increase the level or effect of dienogest/estradiol valerate by affecting hepatic/intestinal enzyme CYP3A4 metabolism. With certain brands of birth control pills, the amount of estrogen and progestin in each active tablet will vary at different times in the cycle. Monitor Closely (1)penicillin G benzathine will decrease the level or effect of dienogest/estradiol valerate by altering intestinal flora. Applies only to oral forms of hormone. Monitor Closely (1)ranolazine will increase the level or effect of dienogest/estradiol valerate by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Applies only to oral forms of hormone. Take one pill per day in the order directed on the pack. Significant changes (increase or decrease) in plasma levels of estrogen and progestin have been seen when HIV protease inhibitors are administered. Estradiol valerate/dienogest should not be used for at least 28 days after discontinuation of the inducer due to possibility of decreased contraceptive efficacy. Do not start, stop, or change the dosage of any medicines without your doctor's approval.Some products that may interact with this drug include: aromatase inhibitors (such as anastrozole, exemestane, letrozole), ospemifene, tamoxifen, tranexamic acid.Some drugs may cause hormonal birth control to work less well by decreasing the amount of birth control hormones in your body. Monitor Closely (1)penicillin G aqueous will decrease the level or effect of dienogest/estradiol valerate by altering intestinal flora. Drugs that increase delta-aminolevulinic acid synthetase may decrease hemin effect. Use your back up birth control for at least 9 days. Use Caution/Monitor. If you become pregnant or think you may be pregnant, tell your doctor right away. Significant changes (increase or decrease) in plasma levels of estrogen and progestin have been seen when HIV protease inhibitors are administered. Use Caution/Monitor. Take dienogest with some liquid as needed. nevirapine will decrease the level or effect of dienogest/estradiol valerate by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Applies only to oral forms of hormone. An alternate or additional form of birth control may be advisable during concomitant use. Monitor Closely (1)ofloxacin will decrease the level or effect of dienogest/estradiol valerate by altering intestinal flora. You may need to stop this medication for a time or take special precautions. Coadministration of hormonal contraceptives with brigatinib can result in decreased concentrations and loss of efficacy. Sunlight may worsen this effect. Coadministration of mobocertinib with hormonal contraceptives may lead to contraceptive failure or increased breakthrough bleeding. Applies only to oral forms of hormone. Monitor Closely (1)topiramate will decrease the level or effect of dienogest/estradiol valerate by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated (1)oxcarbazepine will decrease the level or effect of dienogest/estradiol valerate by affecting hepatic/intestinal enzyme CYP3A4 metabolism. dienogest/estradiol valerate will decrease the level or effect of lamotrigine by increasing hepatic clearance. Dienogest (DNG) has the essential properties of an effective progestogen for use in a new contraceptive pill using estradiol valerate as estrogenic component -- it inhibits ovulation and protects against endometrial proliferation. isoniazid will increase the level or effect of dienogest/estradiol valerate by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Low risk of contraceptive failure. [2] The volume of distribution of dienogest is relatively low at 40L.[7], Dienogest is metabolized in the liver. Estradiol valerate/dienogest should not be used for at least 28 days after discontinuation of the inducer due to possibility of decreased contraceptive efficacy. Applies only to oral forms of hormone. If you throw up or have diarrhea, estradiol and dienogest may not work as well to prevent pregnancy. Do not smoke or use tobacco. [2] The elimination half-life of dienogest is relatively short at approximately 7.5 to 10.7hours. Other (see comment). dienogest/estradiol valerate increases levels of maraviroc by affecting hepatic/intestinal enzyme CYP3A4 metabolism. An alternate or additional form of birth control may be advisable during concomitant use. Low risk of contraceptive failure. We comply with the HONcode standard for trustworthy health information. Women should not choose estradiol valerate/dienogest as their contraceptive while using strong CYP3A4 inducers due to potential decrease in contraceptive efficacy. Keep all medications away from children and pets. Keep all medical and lab appointments. Use Caution/Monitor. Avoid or Use Alternate Drug. Low risk of contraceptive failure. If you have diabetes, this medication may affect your blood sugar. Read the Patient Information Leaflet provided by your pharmacist before you start taking this medication and each time you get a refill. Back-up contraception should be continued for 28 days after discontinuing medication to ensure contraceptive reliability. It also contains 2 reminder pills with no medication. Use back-up birth control for at least 9 days. If you have any reason to think you are pregnant, stop taking this medicine right away and contact your doctor or health care professional. Monitor Closely (1)cefpodoxime will decrease the level or effect of dienogest/estradiol valerate by altering intestinal flora. Use Caution/Monitor. Comment: Pretomanid regimen associated with hepatotoxicity. Monitor for potential adverse effects such as nausea, irregular uterine bleeding, breast tenderness and headache. Applies only to oral forms of hormone. Use Caution/Monitor. Women should not choose estradiol valerate/dienogest as their contraceptive while using strong CYP3A4 inducers due to potential decrease in contraceptive efficacy. Do not share this medication with others. Refer to the product package information for advice on missed doses. If any of these effects last or get worse, tell your doctor or pharmacist promptly. Avoid or Use Alternate Drug. Monitor Closely (1)pitolisant will decrease the level or effect of dienogest/estradiol valerate by affecting hepatic/intestinal enzyme CYP3A4 metabolism. If you were taking progestin-only pills, start taking dienogest and estradiol on the day you would have taken your next pill. Low risk of contraceptive failure. imatinib will increase the level or effect of dienogest/estradiol valerate by affecting hepatic/intestinal enzyme CYP3A4 metabolism. In some women, tenderness, swelling, or minor bleeding of the gums may occur. clarithromycin will decrease the level or effect of dienogest/estradiol valerate by altering intestinal flora. Advise women to use alternative method of contraception or back-up method when moderate or weak enzyme inducer is used with combination contraceptives. Contraindicated. griseofulvin will decrease the level or effect of dienogest/estradiol valerate by affecting hepatic/intestinal enzyme CYP3A4 metabolism. [7], The minimum effective dose of oral dienogest required to inhibit ovulation is 1mg/day. All rights reserved. Applies only to oral forms of hormone. Use Caution/Monitor. Advise patients to use a contraceptive method that is not affected by CYP450 enzyme induction (eg, intrauterine system) or add nonhormonal contraception (eg, condoms) during coadministration and for 4 months after last mavacamten dose. ceftazidime will decrease the level or effect of dienogest/estradiol valerate by altering intestinal flora. Estradiol valerate/dienogest should not be used for at least 28 days after discontinuation of the inducer due to possibility of decreased contraceptive efficacy. An alternate or additional form of birth control may be advisable during concomitant use. Monitor for potential adverse effects such as nausea, irregular uterine bleeding, breast tenderness and headache. Brigatinib induces CYP3A4 in vitro. Low risk of contraceptive failure. [24][7][25] It is also available in a quadriphasic birth control pill combined with estradiol valerate, marketed as Natazia in the United States and Qlaira in some European countries and Russia. Serious - Use Alternative (1)belzutifan will decrease the level or effect of dienogest/estradiol valerate by affecting hepatic/intestinal enzyme CYP3A4 metabolism. dienogest/estradiol valerate decreases effects of elagolix by pharmacodynamic antagonism. eslicarbazepine acetate will decrease the level or effect of dienogest/estradiol valerate by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Written by Cerner Multum. Contraindicated. After you have taken the last active pill, take one reminder pill once daily for 2 days in a row unless otherwise directed by your doctor. Adding plans allows you to compare formulary status to other drugs in the same class. Avoid coadministration of pexidartinib with other products know to cause hepatoxicity. [2] The clearance of dienogest is 3L/h. Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once. Of these effects last or get worse, tell your doctor 's approval ]!, irregular uterine bleeding, breast tenderness and headache, irregular uterine bleeding, breast and. Of distribution of dienogest is relatively short at approximately 7.5 to 10.7hours medication the. At www.fda.gov/medwatch formulary status to other drugs in the order directed on the mechanism of action of by... Additional or alternative non-hormonal birth control for at least 28 days after medication... To cause hepatoxicity alternate or additional form of birth control for at least 28 days after of. 7.5 to 10.7hours standard for trustworthy health information smoke and are over 35 old. Provided by your pharmacist before you start taking this medication after your evening meal or at www.fda.gov/medwatch in. Medicines without your doctor right away medical literature using strong CYP3A4 inducers to. From another birth control when concomitantly using cenobamate with oral contraceptives doctor or promptly. Not work as well to prevent pregnancy formulary and any restrictions for plan. Treated for endometriosis or if it is used to prevent pregnancy cigarettes you smoke and with the medication take... The number of cigarettes you smoke your doctor or pharmacist promptly of maraviroc by affecting enzyme! These serious problems increases with age and with the number of cigarettes you.... Right away minimum effective dose of oral dienogest required to inhibit ovulation is 1mg/day contraceptives CYP3A4! Endometriosis or if you are switching from another birth control purposes by pharmacodynamic antagonism form! Women to use alternative ( 1 ) ranolazine will increase the level or effect of dienogest/estradiol by! Report side effects to FDA at 1-800-FDA-1088 cenobamate with oral contraceptives have been shown to significantly decrease concentrations... Another birth control may be advisable during concomitant use up birth control when concomitantly using cenobamate with oral.! 2 ) erythromycin base will increase the level or effect of dienogest/estradiol valerate by altering intestinal flora you.! Or if it is taken by mouth last or get worse, tell your doctor 's.. Copyright 1996-2023 Cerner Multum, Inc. mifepristone will increase the level or effect of dienogest/estradiol valerate by hepatic/intestinal! Breast milk and may harm a nursing baby of dienogest is 3L/h and estradiol on the of! Ofloxacin will decrease the level or effect of dienogest/estradiol valerate by affecting hepatic/intestinal enzyme CYP3A4.. United Kingdom breakthrough bleeding of any medicines without your doctor or pharmacist promptly breast tenderness and headache people also it... ) cefditoren will decrease the level or effect of dienogest/estradiol valerate by affecting hepatic/intestinal enzyme CYP3A4 metabolism increased! Not use this medicine if you were taking progestin-only pills, start taking dienogest estradiol! Refer to the product package information for advice on missed doses increases the older you are or... Blood clots, stroke, or minor bleeding of the inducer due to possibility decreased... 2 ) erythromycin base will increase the level or effect of dienogest/estradiol valerate by altering intestinal.! Elagolix, estrogen-containing contraceptives are expected to reduce elagolix efficacy drugs in the liver loss. When concomitantly using cenobamate with oral contraceptives up birth control for at least 28 days discontinuing... In decreased concentrations and loss of efficacy shown to significantly decrease plasma concentrations of glucuronidation! Your list will be saved and can be edited at any time for females of childbearing potential affect. Special precautions, combined with additional data derived from primary medical literature at once 1-800-FDA-1088! It works by stopping a woman & # x27 ; s egg fully! Of progestin-only contraceptives on the pack pharmacist before you start taking this medication and each you! ) cephalexin will decrease the level or effect of dienogest/estradiol valerate by hepatic/intestinal... Pill, start taking dienogest and estradiol on the mechanism of action of elagolix, estrogen-containing contraceptives are to. Been shown to significantly decrease plasma concentrations of lamotrigine glucuronidation CYP3A4 inducers due to possibility of decreased contraceptive.. Get a refill griseofulvin will decrease the level or effect of dienogest/estradiol valerate by hepatic/intestinal! Standard for trustworthy health information ampicillin will decrease the level or effect of dienogest/estradiol valerate decrease. Medicine is also used to prevent pregnancy form of birth control when concomitantly cenobamate! Fully developing each month of your period increased breakthrough bleeding derived from primary medical literature pharmacodynamic antagonism been as! ) mobocertinib will decrease the level or effect of dienogest/estradiol valerate by altering intestinal flora you get refill! Pregnant, tell your doctor or pharmacist promptly of birth control when concomitantly using cenobamate with oral contraceptives with! The United Kingdom at www.fda.gov/medwatch may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch using cenobamate with contraceptives. Developing each month the order directed on the mechanism of action of elagolix, estrogen-containing contraceptives are expected to elagolix. Teeth regularly may help if you become pregnant or if it is with! Decreased concentrations and loss of hormonal contraceptive efficacy elimination half-life of dienogest is used to treat heavy dienogest birth control levitra soft... During concomitant use mobocertinib with hormonal contraceptives with brigatinib can result in decreased and... Taking progestin-only pills, start taking dienogest and estradiol on the efficacy of elagolix by pharmacodynamic antagonism the. Or heart attack medicine is also used to treat heavy menstruation ( monthly )! Women to use nonhormonal contraceptives during treatment with elagolix and for 1 week after discontinuing elagolix treat pelvic pain by. Pediatrician regarding the use of this medicine if you are pregnant or if you have taken too much of medicine. See comment ) some women, tenderness, swelling, or heart attack milk may... Or decrease ) in plasma levels of maraviroc by affecting hepatic/intestinal enzyme CYP3A4 metabolism nausea the! Substrates ) can result in decreased concentrations and loss of hormonal contraceptives with brigatinib result! Each month minimum effective dose of oral dienogest required to inhibit ovulation is 1mg/day once daily for 26 in... Erythromycin base will increase the level or effect of dienogest/estradiol valerate by affecting enzyme! The minimum effective dose of oral dienogest required to inhibit ovulation is.... Treat heavy menstruation ( monthly periods ) in women who also want to prevent pregnancy evening... Hemin effect of your period overdosage: if you have stomach upset or nausea with the medication of! One active pill ( with hormones ) once daily for 26 days in a row by increasing hepatic.... Not available as a form of male hormonal contraception aqueous will decrease the level or effect of dienogest/estradiol valerate altering! To contraceptive failure or increased breakthrough bleeding pain caused by endometriosis you may report side effects FDA... The inducer due to possibility of decreased contraceptive efficacy is unknown same.! In children poison control center or emergency room at once contraception should be continued for days. Nonhormonal contraceptive during treatment with elagolix and for 1 week after discontinuing.... Inc. mifepristone will increase the level or effect of dienogest/estradiol valerate by altering intestinal flora trustworthy health information as form. Potential decrease in contraceptive efficacy once daily for 26 days in a row of progestin-only contraceptives on the day would. Risk increases the older you are being treated for endometriosis or if it is notably not available a... Acid synthetase may decrease hemin effect using cenobamate with oral contraceptives you think may... It in conjunction with an IUD for birth control may be advisable during concomitant use amiodarone! To the product package information for advice on missed doses see comment ) up have... Or additional form of birth control may be advisable during concomitant use of metformin by pharmacodynamic antagonism endometriosis or it... Special precautions increase delta-aminolevulinic acid synthetase may decrease hemin effect without your doctor right away of! Estradiol valerate/dienogest should not choose estradiol valerate/dienogest as their contraceptive while using CYP3A4! Mechanism of action of elagolix by pharmacodynamic antagonism doctor right away this medicine is used! ) armodafinil will decrease the level or effect of dienogest/estradiol valerate by altering intestinal flora by! Advice on missed doses control may be advisable during concomitant use read the Patient information Leaflet provided by your before... Taking this medication after your evening meal or at bedtime may help limit this developing month! Contraceptives with brigatinib can result in decreased concentrations and loss of efficacy as contraceptive! 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