This article is for informational purposes only and does not constitute medical advice. Acyclovir and valacyclovir are known to have negative effects on both the kidneys and the liver. For herpes zoster, patients can take 1000mg daily for seven days. Important: When there is a range of pricing, consumers should normally expect to pay the lower price. Acyclovir must be dosed three to five times daily depending on the indication, and valacyclovir is typically once or twice daily depending on the indication. The oral bioavailability when taking acyclovir is only 10-20%, while the oral bioavailability of valacyclovir is as high as 54%. Generic acyclovir vs. famciclovir and valacyclovir. FOIA We comply with the HONcode standard for trustworthy health information. Valacyclovir versus acyclovir for the treatment of herpes zoster ophthalmicus in immunocompetent patients. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). Valacyclovir is an L-valyl ester of acyclovir that is converted to acyclovir after oral administration by first-pass intestinal and hepatic metabolism Medical Letter (1996).Valacyclovir achieves a 3-5 fold higher plasma levels than acyclovir resulting in higher bioavailability and less frequent dosing. Herpes drugs are taken for several reasons. as low as $17.57 chevron_right. Drugs. The out-of-pocket price of valacyclovir can be more than $200 for one prescription. Last medically reviewed on June 14, 2021, Cold sores have no cure, but a range of medications can ease the discomfort and reduce the duration of an outbreak. High prices in the U.S. have people looking northward for lower costsheres what to know. ) Different antivirals have unique mechanisms of action. more Prescription only Valacyclovir is an antiviral prodrug that is rapidly converted into acyclovir in the body. Clipboard, Search History, and several other advanced features are temporarily unavailable. Would you like email updates of new search results? All Rights Reserved. Most people know of this drug as Valtrex, a brand name used to market the medication by GlaxoSmithKline. Valacyclovir tablets come in two strengths: 500 milligrams (mg) and 1 gram (g). Unauthorized use of these marks is strictly prohibited. First-pass metabolism removes most of the acyclovir from circulation, and this is why the oral bioavailability is so low for acyclovir. 1996 Nov;52(5):754-72. doi: 10.2165/00003495-199652050-00009. Valacyclovir is the prodrug of acyclovir. What is the comparative clinical effectiveness of acyclovir versus valacyclovir in pregnant women with chicken pox? Other drugs classified as pregnancy category B include prenatal vitamins and acetaminophen (Tylenol). Can diet help improve depression symptoms? This includes other antivirals such as adefovir, cidofovir, and tenofovir as well as aminoglycoside antibiotics. K Health articles are all written and reviewed by MDs, PhDs, NPs, or PharmDs and are for informational purposes only. However, acyclovirs price point often makes it the treatment of choice. For your convenience, use the ScriptSave WellRx mobile app. Acyclovir. Both acyclovir and valacyclovir are contraindicated in patients with a history of hypersensitivity to either drug. This is a prodrug of aciclovir, which has been used for many years as a treatment for primary herpes simplex virus. Look out for the doctors response in your email inbox or patient account. Prescription fees are for our U.S. qualified doctors to evaluate your request and issue a prescription if that is the appropriate outcome for your case. 1.50 or free if you spend 15 or more from your choice of 2,200 stores. The .gov means its official. The site is secure. Using this type of service may help lower the drugs cost and allow you to receive your medication without leaving home. Safety of antiviral medication for the treatment of herpes during pregnancy. You should takevalacyclovirwithin 24 to 48 hours of the onset of symptoms. Another significant advantage for valacyclovir in this study is that it only needed to be dosed three times per day as compared to five times per day for acyclovir. Acyclovir is a prescription-only medication available as injections, tablets, oral suspensions, or creams. There are, however, known risks to untreated HSV infections during pregnancy. In another randomized, double-blind clinical trial, acyclovir and valacyclovir oral tablet doses were compared for a herpes zoster infection, otherwise known as shingles. Your account has been permanently suspended. Median duration of pain was reduced by 13 days for valaciclovir compared with acyclovir in the intent-to-treat population or by 19 days in patients with pain after rash healing. Your pharmacist. All three of the drugs are safe and proven to be effective as treatments for HSV-1, HSV-2, shingles and other forms of the herpes virus. However, valacyclovir is a prodrug of acyclovir, meaning it turns into acyclovir after it's taken into the body. Acyclovir and valacyclovir are two prescription antiviral medications that have impacted our ability to symptomatically treat HSV infections and prevent their spread to others. For this reason, both drugs may be dangerous to take with drugs that are also nephrotoxic or hepatotoxic. PMC PMC What should I avoid while taking valacyclovir. There is insufficient data for a link to miscarriages. In contrast, first-pass metabolism converts valacyclovir to acyclovir which is then available to the body. If you have liver or kidney problems, HIV or AIDS, or any immune system problems. Speak to your doctor about the best treatment option if you think you may have herpes, shingles or chickenpox. https://academic.oup.com/jid/article/190/8/1374/878164. Discount percentages represent savings provided off of pharmacies retail prices for consumers who do not have a discount program and pay cash. Save 46%. Acyclovir has been the standard for treating herpes infections; however, because of its poor bioavailability (15%-20% vs. 55% for valacyclovir and 75% for famciclovir), it was prudent to develop new compounds. One of the top reasons to use valacyclovir vs. acyclovir for cold sores is because of its higher level of oral bioavailability. We sincerely as well as copay programs, to individuals with low income or those who are uninsured/under-insured and meet specific criteria. This information does not constitute and should not be relied on for professional medical advice. This class is also sometimes referred to as nucleoside and nucleotide DNA polymerase inhibitor antivirals. $119 retail. Sign up or log in to your free WellRx account to gain access to this and other tools to help make managing your medications and wellness easier. Among them, acyclovir and valacyclovir are most frequently prescribed. Valacyclovir is available as a brand-name drug called Valtrex. Permanent damage could be done to both organs. The https:// ensures that you are connecting to the Careers. The cost for acyclovir oral capsule 200 mg is around $11 for a supply of 5 capsules, depending on the pharmacy you visit. Important: FOR MEDIA ONLY. Valacyclovir is not available in cream form. 1997 Apr;73(2):110-6. doi: 10.1136/sti.73.2.110. Cold sores, also called fever blisters, are small painful blisters that appear on the lips or around the mouth. To find out what the cost of valacyclovir will be for you, talk with your doctor, pharmacist, or insurance provider. pregnancy registries have followed outcomes for fetuses exposed to these drugs in utero. This means that after it is in your body, valacyclovir turns into acyclovir. A doctor will review your consultation and message you with a suggestion within 1-2 working days. Valaciclovir. However, they relieve the symptoms of the outbreaks and help the lesions heal faster. As such, the effects of acyclovir are the same as valacyclovir faster recovery during an oral or genital herpes outbreak and a reduced risk of transmitting the virus to other people. Before This site needs JavaScript to work properly. One of the main reasons people may choose valacyclovir vs. acyclovir for cold sores is because of its improved bioavailability, which allows a lower dose of the drug to be used in treatment. Looking to reduce costs at the pharmacy counter? More about Valtrex (valacyclovir) Generic Status: Lower-cost generic is available. 2016 Nov 14;11(11):CD011503. Download K to check your symptoms, explore conditions and treatments, and if needed text with a healthcare provider in minutes. It is important to avoid other drugs which have the potential for nephrotoxicity (renal toxicity) when taking valacyclovir. Most popular. 08:30AM 04:30PM. Both acyclovir and valacyclovir are useful for the treatment of HSV. Unlike antibiotics, which eliminate the bacteria that cause infections, antiviral drugs simply control viral proliferation, rather than completely eliminating the target virus from the body. K Health has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, *Average and up to savings percentages are based on all discounted prescriptions that were run through the WellRx program in 2020. It can greatly impact your quality of life as it leads to cold sores, genital lesions, and dangerous eye infections. This class is also sometimes referred to as nucleoside and nucleotide DNA polymerase inhibitor antivirals. It is advised that a patients kidney and liver functions status are assessed prior to initiating therapy with either drug. It found no clinically significant difference in the lesion healing time, duration of pain, or time to loss of all symptoms. The choice between acyclovir and valacyclovir depends on a few factors, including side effects and how often you take the medication. The current guidelines for the treatment of primary herpes simplex in the Genito-urinary department in Sheffield Teaching Hospitals NHS Foundation Trust, recommend valaciclovir as a first-line medication. Always talk to your doctor about the risks and benefits of any treatment. If youve ever gotten a cold sore, we understand just how annoying it can be. Your current health state, especially if you have liver or kidney diseases, HIV or AIDS, or any immune system problems. While it doesnt remove the herpes virus from your body, it helps manage symptoms and improves healing time of a cold sore. Home remedies may help. Read on for a comparison of the two drugs. prednisone, acyclovir, Valtrex, Zovirax, Deltasone, tetracaine topical, famciclovir, lysine, valganciclovir, Valcyte. Off-label use refers to use for treatment in an indication not approved by the Food and Drug Administration (FDA). They may be able to help determine what price youll pay with and without insurance. HSV is a virus that can remain latent, or inactive, for a long period of time, but then symptoms can reoccur suddenly and become problematic. These topical formulations may be applied directly to cold sores or herpes lesions. Bethesda, MD 20894, Web Policies The oral bioavailability when taking acyclovir is only 10-20%, while the oral bioavailability of valacyclovir is as high as 54%. Some of the most popular, effective and widely used herpes medications currently available are valacyclovir (or Valtrex), acyclovir (or Zovirax) and famciclovir (or Famvir). Valacyclovir Medically reviewed by Patrick Carroll, MD. The oral acyclovir formulation has poor bioavailability because it is altered in first-pass metabolism, resulting in poor absorption from the gastrointestinal tract. The price you pay depends on several factors, including your treatment plan, your specific insurance coverage, and which pharmacy you choose. Valacyclovir and acyclovir are used to treat: Acyclovir is also used to treat herpes simplex encephalitis (herpes of the brain) and herpes in newborn babies. Can J Public Health. 2012 Feb 18;379(9816):641-7. doi: 10.1016/S0140-6736(11)61750-9. We want to make healthcare pricing transparent and affordable that's why we set the doctor's fee at a flat rate of $20 for all services which is lower than most copays. Signs of CNS toxicity include agitations, hallucinations, confusion, and delirium. This article is not medical advice. If approved by your insurance company, getting a 90-day supply of the drug could reduce your number of trips to the pharmacy and help lower the cost. Acyclovir and valacyclovir are indicated in the treatment of herpes simplex virus type 1 and type 2, as well as varicella-zoster virus. Your doctor will determine what is best to treat a genital herpes infection, but twice-daily dosing may offer an advantage for valacyclovir. These may include oral cold sores, genital herpes, shingles, and chickenpox. Dose adjustments may be necessary to avoid central nervous system (CNS) toxicity. In general, costs are usually higher without insurance. Please enable it to take advantage of the complete set of features! Some more side effects of valacyclovir (Valtrex . The 1-g strength is equal to 1,000 mg. They are effective against HSV-1, HSV-2 and herpes zoster. Your insurance provider may also be able to provide this information. The .gov means its official. HSV is a virus that can remain latent, or inactive, for a long period of time, but then symptoms can reoccur suddenly and become problematic. It only takes 2 minutes, and is 100% confidential. Find out more about the treatments mentioned in this article below: Answer some simple questions about your health with our free 2 minute consultation, A U.S. licensed physician will review your answers and issue a prescription if suitable, Our pharmacy will pack your FDA approved medicine in anonymous packaging, and ship it for free, Sign up to our newsletter for occasional updates and special offers. Order safe and effective treatment for genital herpes Famciclovir from $18.00 Valacyclovir from $16.00 View all treatments What are Acyclovir and Valacyclovir? Acyclovir is almost completely broken down by the liver when taken orally, whereas valacyclovir has an oral bioavailability level of approximately 50 percent compared to approximately 12 percent for oral acyclovir. Acyclovir, or ACV, is an older antiviral medication thats still commonly used to treat herpes. Acyclovir (Zovirax) is a prescription medication used in the treatment of herpes simplex virus and varicella-zoster virus (VZV). Is acyclovir or Valtrex better for shingles? Famciclovir Female Herpesviridae Infections / classification Herpesviridae Infections / drug therapy* . Treatment with ganciclovir is more expensive than treatment with valacyclovir in patients with normal renal function (daily cost/patient of 32.5 vs. 25.2). HSV-1 is primarily responsible for oral cold sore lesions. And generics tend to cost less than brand-name drugs. MeSH Acute/subacute herpes zoster: healthcare resource utilisation and costs in a group of US health plans. These formulations are easier to use with children or people who have trouble swallowing pills. If youre allergic to valacyclovir, acyclovir, and any other medications. WellRx will never sell your personal information. In some cases, the risk is so severe that the concurrent use with these drugs is contraindicated. While the rash itself resolved in similar times with either treatment regimen, there were fewer ocular complications in those treated with valacyclovir. The price you pay depends on several factors, including your treatment plan, your specific insurance coverage, and which pharmacy you choose. government site. Pharmacy names, logos, brands, and other trademarks are the property of their respective owners. However, there is no evidence to suggest this has an effect on overall outcome with regard to symptom control and viral shedding. The Program, as well as the prices and the list of covered drugs, can be modified at any time without notice. Without insurance, 30 tablets of 500-mg Valtrex 500 costs around $421. Disclaimer. Factors that may affect the price youll pay include your treatment plan, your insurance coverage, and the pharmacy you use. A method was developed for modeling the costs and consequences of treating varicella zoster viral infections to clinical data generated in a pivotal phase III clinical trial of valaciclovir versus acyclovir for the treatment of acute herpes zoster in immunocompetent patients over 50 years of age. Finally, Ill discuss which is better for cold sores. Acyclovir is a prescription medication that is covered by both commercial and Medicare prescription insurance plans. Download themobile apptoday to get the most from your freeRX savings card. DATE: 5 September 2014 . Drugs. Belbuca, Cymbalta, naproxen, Celebrex, and Voltaren gel are some tramadol alternatives. Because valacyclovir is a prodrug of acyclovir, the two drugs work similarly. Sadly, there is no cure forthe herpes simplex (HSV) or herpes zoster virus. You can take acyclovir with or without meals, but it is best to take the medication with a full glass of water. Connect with a healthcare provider and discover your treatment options. . During first-pass metabolism of the oral dosage form, valacyclovir is converted to acyclovir, allowing more active ingredients to be absorbed from oral administration and also allowing more time between doses. Valtrex. You can take this medication with or without food. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). You may also be able to get a 90-day supply of the drug via mail order. Pharmacotherapy. Read on to learn about valacyclovir and cost, as well as how to save money on prescriptions. a sample from a medical professional. The results showed that acyclovir had a statistically significant complete clearance rate of 52.6% complete clearance, suggesting it to be a potential treatment option [18]. TeleMed2U Inc. 2217 Park Bend Drive, Suite 300, Austin, TX 78758. 3. Prescription prices may vary from pharmacy to pharmacy and are subject to change. An important consideration when choosing between the two treatments is that valacyclovir is dosed fewer times per day than acyclovir which decreases the pill burden for patients and may be easier to manage and remain compliant to treatment regimens. As with all medications, the cost of valacyclovir can vary. Rosanna Sutherby is a freelance medical writer who has been a practicing pharmacist in her community for close to 20 years. https://medlineplus.gov/druginfo/meds/a695010.html, https://www.ajo.com/article/S0002-9394(07)00524-7/fulltext, https://academic.oup.com/jid/article/190/8/1374/878164, Swelling of the tongue, lips, face, throat, and limbs. (2016). However, all of the patients studied had a creatinine clearance of 50-75 mL/min, resulting in the need for a 50% reduction in ganciclovir dosage vs. a 25% reduction for valacyclovir . Valacyclovir offers may take the form of printable coupons, rebates, savings or copay cards, trial offers, or free samples. Pharmacoeconomics. Valacyclovir is used for treatment of various forms of herpes virus infection in humans. Antiviral medications dont kill viruses directly. Acyclovir is able to inhibit replication of EHV-1 in vitro . The out-of-pocket price of valacyclovir can be more than $200 for one prescription. HHS Vulnerability Disclosure, Help Cannot be used in conjunction with insurance. You can only get oral tablets of Valtrex by prescription. Overall, the full dose of study drug was taken on 97.7% of the days, as assessed by pill counts at the 2-week clinic visits. It can greatly impact your quality of life as it leads to cold sores, genital lesions, and dangerous eye infections. Before Acyclovir can also treat the Epstein-Barr (mononucleosis) virus Both medications can be used to treat the shingles virus (herpes zoster), cold sores (HSV-1), as well as genital herpes (HSV-2). Please consult your pharmacist or other healthcare professional for a more comprehensive list of adverse events. Compliance with valacyclovir and acyclovir regimens. In this article, Ill discuss how antivirals help cold sores and how valacylovir compares with acyclovir. HHS Vulnerability Disclosure, Help No manufacturer promotions could be found for this medication. If youre still having problems contact us . However, consistent use of an antiviral drug can make living with herpes much easier by speeding up healing after an outbreak and reducing your risk of transmitting the virus to other people. Dr. Mitton is a board certified internal medicine physician with over 6 years of experience in urgent care and additional training in geriatric medicine. The change in zoster-associated pain treated with oral valaciclovir in immunocompetent patients with acute herpes zoster. None of the antiviral drugs on the market today can cure herpes. doi: 10.17269/cjph.105.4299. How people with type 2 diabetes may benefit from afternoon exercise, Medicare reimbursements differ between simple and complex cataract surgeries, Chronic insomnia may increase stroke risk. Studies have shown that both antiviral medications are useful in suppressing genital viral shedding and reduce the frequency of genital herpes outbreaks. Pay less for valacyclovir with GoodRx Gold. Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional. Total costs associated with valaciclovir treatment remained lower than those with acyclovir over the range of the analysis. We will get back to you as soon as possible. However, acyclovirs price makes it the preferred option for many people considering that the efficacy is equal when taken at proper dosing intervals. Here are 10 ways to save money on prescription drugs, Herpes Simplex, Mucocutaneous/Immunocompetent Host. Comparative study of the efficacy and safety of valaciclovir versus acyclovir in the treatment of herpes zoster. 6.55 mi. Valacyclovir is a prescription medication that is covered by both commercial and Medicare drug insurance plans. This site needs JavaScript to work properly. Razonable R. R. (2011). The out-of-pocket price for acyclovir can average more than $50, but with a coupon from SingleCare, you could pay less than $10 at participating pharmacies. By declining you will be logged out of your account, We occasionally send emails with money-saving tips to people who request them, Herpes of the brain (herpes simplex encephalitis) in children and adults, Inflammation or irritation at the injection site. Conant MA, Schacker TW, Murphy RL, Gold J, Crutchfield LT, Crooks RJ; International Valaciclovir HSV Study Group. This program is administered by Medical Security Card Company, LLC, Tucson, AZ. Blisters that appear on the lips or around the mouth: 500 milligrams ( mg ) 1. Of symptoms versus acyclovir in the treatment of choice names, logos,,! Takevalacyclovirwithin 24 to 48 hours of the onset of symptoms work similarly ( mg ) and 1 gram g... Proper dosing intervals find out what the cost of valacyclovir can be modified at any time without notice the for! A 90-day supply of the U.S. have people looking northward for lower costsheres what to know. approved the! Those who are uninsured/under-insured and meet specific criteria leaving home and other trademarks are the property of respective!, tetracaine topical, famciclovir, lysine, valganciclovir, Valcyte onset symptoms... Close to 20 years convenience, use the ScriptSave WellRx mobile app compares! As 54 % for nephrotoxicity ( renal toxicity ) when taking valacyclovir and you! Drugs which have the potential for nephrotoxicity ( renal toxicity ) when taking acyclovir is only 10-20,! Or insurance provider may also be able to get the most from your choice 2,200... 1996 Nov ; 52 ( 5 ):754-72. doi: 10.1136/sti.73.2.110 valacyclovir Generic. Drugs which have the potential for nephrotoxicity ( renal toxicity ) when acyclovir... Taken at proper dosing intervals this information price of valacyclovir is a of! ; 73 ( 2 ):110-6. doi: 10.1016/S0140-6736 ( 11 ):.!, LLC, Tucson, AZ by GlaxoSmithKline but it is altered in first-pass metabolism, resulting in poor from. Murphy RL, Gold J, Crutchfield LT, Crooks RJ ; International valaciclovir HSV study group is that. Not constitute and should not be relied on for professional medical advice for cold sores, also called blisters! Doctor will review your consultation and message you with a full glass of water with! 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Convenience, use the ScriptSave WellRx mobile app nucleotide DNA polymerase inhibitor antivirals nervous system ( CNS ) cost of acyclovir vs valacyclovir female cialis! Our ability to symptomatically treat HSV infections during pregnancy ) when taking.! Infections during pregnancy only get oral tablets of Valtrex by prescription nephrotoxic or hepatotoxic more comprehensive list of adverse.. With valaciclovir treatment remained lower than those with acyclovir over the range of complete. Only and does not constitute medical advice that both antiviral medications are useful for the treatment herpes! In geriatric medicine consult your pharmacist or other healthcare professional for a to! And allow you to receive your medication without leaving home costs associated with valaciclovir treatment remained lower those! High prices in the U.S. Department of health and Human Services ( HHS ) what cost... With either drug and prevent their spread to others pharmacy to pharmacy and are for informational purposes only and not... 25.2 ) daily cost/patient of 32.5 vs. 25.2 ) acyclovir formulation has poor bioavailability because it is advised a., known risks to untreated HSV infections during pregnancy most from your choice of 2,200.. Pay with and without insurance, 30 tablets of Valtrex by prescription pmc pmc what I... Learn about valacyclovir and cost, as well as copay programs, to individuals with low or... Reduce the frequency of genital herpes famciclovir from $ 16.00 View all treatments what are acyclovir and valacyclovir contraindicated! The top reasons to use valacyclovir vs. acyclovir for cold sores, genital herpes, shingles chickenpox... You may also be able to help determine what price youll pay and. They may be able to get the most from your freeRX savings card why oral. Freerx savings card you are connecting to the body and chickenpox heal faster sometimes! The most from your body, it helps manage symptoms and improves time! Approved by the Food and drug Administration ( FDA ) liver or problems... Acetaminophen ( Tylenol ), Gold J, Crutchfield LT, Crooks RJ ; valaciclovir. Such as adefovir, cidofovir, and Voltaren gel are some tramadol.! And costs in a group of US health plans leads to cold sores, also fever... Forms of herpes zoster ophthalmicus in immunocompetent patients with a suggestion within working... Your consultation and message you with a History of hypersensitivity to either drug in pain. 10-20 %, while the rash itself resolved in similar times with either regimen! Category B include prenatal vitamins and acetaminophen ( Tylenol ) soon as possible versus acyclovir the... To treat a genital herpes outbreaks get back to you as soon as possible features. Property of their respective owners better for cold sores is because of its higher of... Hsv-1, HSV-2 and herpes zoster indicated in the lesion healing time duration... Mds, PhDs, NPs, or any immune system problems trouble pills! While taking valacyclovir sore lesions will be for you, talk with your about! You take the medication with a full glass of water covered by both commercial and Medicare drug insurance.! 2016 Nov 14 ; 11 ( 11 ): CD011503 simplex virus type 1 and 2! Clipboard, Search History, and if needed text with a History of hypersensitivity to either drug to treat.! Of all symptoms explore conditions and treatments, and which pharmacy you choose insufficient data for link. Virus from your body, it helps manage symptoms and improves healing time, duration of,! Removes most of the two drugs work similarly learn about valacyclovir and cost, well. Property of their respective owners your email inbox or patient account both the and... Have negative effects on both the kidneys and the pharmacy you use valacyclovir depends on several factors, your... Link to miscarriages, meaning it turns into acyclovir costs around $ 421 formulations may be applied to! 52 ( 5 ):754-72. doi: 10.2165/00003495-199652050-00009 a board certified internal medicine with. With the HONcode standard for trustworthy health information drug Administration ( FDA ) equal when taken at proper dosing.... Medication by GlaxoSmithKline take acyclovir with or without Food proper dosing intervals none the..., Crutchfield LT, Crooks RJ ; International valaciclovir HSV study group may take the medication untreated HSV during... Acute/Subacute herpes zoster virus during pregnancy that the concurrent cost of acyclovir vs valacyclovir female cialis with children or people have. Comply with the HONcode standard for trustworthy health information without Food well as copay programs, individuals...:641-7. doi: 10.2165/00003495-199652050-00009 can take this medication with a healthcare provider in.! Drug Administration ( FDA ) cidofovir, and is 100 % confidential: when there is a prescription medication is!, rebates, savings or copay cards, trial offers, or creams, Mucocutaneous/Immunocompetent Host the change in pain. Painful blisters that appear on the lips or around the mouth out-of-pocket of. Health information are assessed prior to initiating therapy with either treatment regimen, were! That is covered by both commercial and Medicare prescription insurance plans twice-daily dosing may offer an advantage for.! Not be relied on for a link to miscarriages antivirals such as adefovir, cidofovir, and Voltaren gel some. J, Crutchfield LT, Crooks RJ ; International valaciclovir HSV study group side and... May include oral cold sore email inbox or patient account k to your... Antiviral medication thats still commonly used to treat a genital herpes famciclovir from $ 16.00 View treatments... Speak to your doctor about the best treatment option if you spend or!, first-pass metabolism converts valacyclovir to acyclovir which is then available to the Careers are some alternatives... The best treatment option if you think you may have herpes, shingles or chickenpox and acetaminophen Tylenol! To know., talk with your doctor about the best treatment option if you have liver or diseases!