If your cycle is frequently shorter than 21 days, leading you to bleed earlier than you normally do, it could be a sign of something underlying. 513 views Reviewed >2 years ago. Infections linked with sexual activity that are usually treated with metronidazole include bacterial vaginosis, trichomoniasis, and moderate-to-severe pelvic inflammatory disease. But it may take a couple of days before you start to feel better or notice an improvement in your symptoms. For these, please consult a doctor (virtually or in person). aspirin and ibuprofen. Maintain a healthy weight. It can also cause: Endometriosis occurs when endometrium-like tissue begins to grow outside the uterus in areas like the ovaries, abdomen, and bowel. Erectile dysfunction (ED) is often a symptom . If you buy through links on this page, we may earn a small commission Heres our process. Continue reading. Metronidazole is also used to treat trichomoniasis, a sexually transmitted disease caused by a parasite. The phenomenon of completing a course of antibiotics and experiencing period-like symptoms, along with a delayed or early period, leaves some women with unanswered questions because there's little scientific evidence available that explains exactly why this happens. However, BV often accompanies other conditions that could cause vaginal bleeding, such as STDs . MNT is the registered trade mark of Healthline Media. Learn about its more common, mild, and serious side effects, Augmentin and amoxicillin are similar antibiotics that doctors prescribe to treat bacterial infections. Any odors during your period can also fluctuate. Site by Maze Creative. Gut flora starts replenishing as soon as we complete a course of antibiotics, and our diets are likely to help it along.. For pregnant people: Talk with your doctor if youre pregnant or planning to become pregnant. If this happens every once in a while, it is likely no cause for concern, as variations in the menstrual cycle are common. Dont store this medication in moist or damp areas, such as bathrooms. Brand names: Flagyl, Flagyl ER, Flagyl I.V., RTU, Metro I.V., Protostat, Metryl Many prescription and nonprescription medicines can affect the menstrual cycle. (2019). A black box warning indicates drug effects that. As a result, more of a drug stays in your body for a longer time. Lifestyle factors. If youre taking birth control pills, the timing of your next period will depend on when during your cycle you started taking the pills and whether youre taking a week of placebos (reminder pills). Black, Brown, Bright Red, and More: What Does Each Period Blood Color Mean? It is also used to treat endocarditis (infection of the heart lining and valves), meningitis (infection of the membranes that surround the brain and spinal cord), and certain respiratory infections, including pneumonia. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Check with your healthcare provider if any of the following side effects continue or are bothersome: 3. diarrhea. You should not breastfeed within 24 hours after using metronidazole. Read: How Drug Use Affect Period In Women. What are 3 factors that can affect the menstrual cycle? You should always consult your doctor or another healthcare professional before taking any medication. However, some doctors believe that more research is needed on this topic. Do not drink alcohol or consume foods or medicines that contain propylene glycol while you are taking metronidazole and for at least 3 days after you stop taking it. Why Did Your Period Come Early? Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. Carry your medication with you. Keep using this medicine even if your symptoms quickly improve. Store at room temperature away from moisture and heat. My period that cycle was delayed until day 35, and my periods are pretty regular so that was very unusual for me.. Heavy menstrual bleeding: Frequently asked questions. FAQ Metronidazole oral tablets and capsules have a black box warning. Metronidazole injection is also used to prevent infection when used before, during, and after colorectal surgery. You might see changes to your normal menstrual cycle including: These changes arent caused by the antibiotics but can be caused by feeling unwell enough to need antibiotics. Metronidazole comes in several forms. Sometimes, irregular periods can be caused by some medicines, exercising too much, having a very low or high body weight, or not eating enough calories. Can I be pregnant if my period is 6 days late? There are many reasons your period could be delayed. Stress and hormones. These conditions include: Call your doctor right away if you have symptoms such as: Metronidazole can cause a severe allergic reaction or hypersensitivity. This means you may need to take it with other medications. Share on Pinterest. Plus, Why Its Late. Severe diarrhea, fever. Fortunately, many of them arent a cause for serious concern. 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You can learn more about how we ensure our content is accurate and current by reading our. You may have unpleasant effects such as headaches, nausea, vomiting, stomach cramps, and warmth or tingling under your skin. thyroid medications. Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available. This can be harmful or prevent the drug from working well. They can use this information to evaluate your cycle and advise you on any next steps. If you use EC pills routinely, your period may become irregular. Taking antibiotics doesn't generally have any impact on your period. If you use a breast pump during this time, throw out the milk and do not feed it to your baby. This information is not a substitute for medical advice. Often, the stress of being sick is enough to cause a delay in your period. It arrives every month, exactly on time, and I only experience very slight breast pain, rather than sore, painful, and swollen breasts. In some cases, taking it again could lead to death. This increases the amount of the drug in your body and raises your risk of side effects. Your doctor will write the number of refills authorized on your prescription. We may soon have a pregnancy-like test for endometriosis. These tablets are available as the brand-name drugs Flagyl (immediate-release) and Flagyl ER (extended-release). A healthcare provider will give you the injection if you are unable to take the medicine by mouth. Likewise, taking oral Flagyl antibiotic doesn't create a problem with one's Metronidazole can darken urine but I am uncertain about effects on color of menstrual blood. (2009). In the first few years after you get your period, these hormones can be irregular. When bleeding after anal sex is normal, and when its not, What do anal orgasms feel like? Orange book: Approved drug products with therapeutic equivalence evaluations. Symptoms can include: Do not take metronidazole if youve taken disulfiram in the last two weeks. They cant hurt your medication. But if you notice an unusual, A long period, or a period that lasts for more than 7 days, may be a sign of an underlying health conditions. Metronidazole is also used to treat trichomoniasis, a sexually transmitted disease caused by a parasite. dizziness or light-headedness. Researchers dont know exactly why this happens, but it may be related to a disruption in your circadian rhythm. Eat pineapple. They can vary for many reasons and in many ways. The Femedic 2023. When a womans period is seven days late she may be pregnant although other things may cause a late or skipped period. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Last medically reviewed on December 18, 2020. Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Metronidazole is used to treat various infections caused by bacteria or parasites. Will it give me thrush? Shake the oral suspension (liquid). Healthline Media does not provide medical advice, diagnosis, or treatment. It isnt uncommon for people to experience breakthrough bleeding after their doctor inserts an IUD. Review/update the It often happens before the person is aware of the pregnancy, so it can be difficult to differentiate between a particularly heavy period and a miscarriage. Ask your doctor about your risk. Switching time zones may have similar effects. Flagyl: Uses, Dosage, Side Effects, Abuse and Alcohol, PLIVA 334 Pill: Uses, Dosage, Side Effects, Interactions. Antibiotic and Oral Contraceptive Drug Interactions: Is There a Need for Concern?. PCOS is a common condition caused by a hormonal imbalance. Your period may come early due to changes in your hormone levels. It's important to always see your doctor, A period that lasts one or two days could be a sign of pregnancy, but there are many other reasons for a one- or two-day period. The kidneys and liver of older adults may not work as well as they used to. 4.9k views Reviewed >2 years ago. This also wasnt the first time my period had gone rogue during a course of antibiotics. Although metronidazole spares vaginal lactobacilli, which are naturally resistant to nitroimidazoles such as metronidazole, it does not restore a Lactobacillus-dominated microbiome and disruption in the normal vaginal microbiota can persist. thyroid medications. Oestrogen that has only experienced one cycle of breakdown is more toxic and once it re-enters the bloodstream, this can cause period irregularities and symptoms, like cramping and bloating. (2002). You'll soon start receiving the latest Mayo Clinic health information you requested in your inbox. Examples include: Disclaimer: Our goal is to provide you with the most relevant and current information. Your cycle starts on the first day of your current period and ends on the first day of your next period. Changes in your weight can affect your periods. Understand the link between your stress levels and your thyroid. Nitroimidazole antimicrobials treat infections caused by bacteria and other organisms called protozoa. Learn more here. epilepsy drugs. That doesnt mean you might not have a delayed period after taking antibiotics. If youve been under extra stress lately, you might be able to get your period back on track by working on lowering your stress level. In some cases, they may need to remove lingering tissue from your uterus. (2018). Neither does BV itself. Continue reading. . Oral: 15 to 50 mg/kg/day orally in 3 divided doses. To make sure you can safely take this medicine, tell your doctor if you have ever had: kidney disease (or if you are on dialysis); a stomach or intestinal disease such as Crohn's disease; a blood cell disorder such as anemia (lack of red blood cells) or low white blood cell (WBC) counts; a fungal infection anywhere in your body; or. According to Mayo Clinic, PID occurs when bacteria makes its way into the vagina and cervix. Certain sexually transmitted infections (STIs). Antimicrobials are drugs used to treat infections. More in Metronidazole About metronidazole Who can and cannot take it Talk with your doctor or pharmacist if theyre more severe or dont go away. An early period here and there usually isnt cause for concern. While it seems logical to assume the antibiotics are responsible for this change to the menstrual cycle, theres actually no scientific evidence to back this up. This is because the amount of either drug may be increased in your body. Rotating shift work and menstrual cycle characteristics. Could a new blood biomarker help predict Alzheimer's risk? The kidneys and liver of older adults may not work as well as they used to. Spice things up with ginger. Continue using this medicine even if your menstrual period starts during the time of treatment. Keep it in your carry-on bag. Everything from stress to serious illness can cause a late or skipped period. Changes in your routine can affect your hormones and cause your period to come early or late. Drug classes: Amebicides, Miscellaneous antibiotics. If you have severe liver disease, your liver may process this drug more slowly. Contact your doctor if you experience these side effects and they are severe or bothersome. When traveling with your medication, follow these tips: There are other drugs available to treat your condition. What if I do not get better? There may be still a risk. See additional information. May harm an unborn baby. If you have missed your period for over 90 days and are not pregnant, talk to your doctor about getting tested for any underlying medical conditions. The most common early signs and symptoms of pregnancy might include: Missed period. Immediate-release drugs are released into the body right away. Antibiotics can disrupt the balance of both these groups of bacteria, minimising the estrobolome and encouraging an overgrowth of beta-glucuronidases. Store this drug at a temperature below 77F (25C). If you arent experiencing any severe symptoms, you may be able to regulate things at home. Consequences of oral anticoagulation on menstrual bleeding and contraceptive use. Thank. Stress. However, if youve had multiple late and unpredictable periods, its a sign to see a healthcare professional. This can also put your body under physical stress, which may get worse if you need to miss work or cancel plans. DOI: Rebar RW. Pain, tingling, or numbness in the hands or feet. Studies of the drug in pregnant animals have not shown a risk to the fetus. Nervous system effects, including seizures and encephalopathy (abnormal brain function). The most likely cause for an irregular period on antibiotics is usually the infection for which an antibiotic was prescribed. You can learn more about how we ensure our content is accurate and current by reading our. What is the difference between Augmentin and amoxicillin? Johnson KA, et al. Is it safe to use metronidazole and birth control together? Understand the link between your stress levels and your thyroid. Call your doctor for medical advice about side effects. Metronidazole is in a class of medications called nitroimidazole antimicrobials. Metronidazole oral tablet can interact with other medications, vitamins, or herbs you may be taking. Metronidazole oral tablet is safe to use with hormonal birth control methods. They can help you figure out whats causing your late periods and develop a treatment plan to help address the problem. For people with kidney disease: Your kidneys help clear this drug from your body. When the body enters starvation mode, it reserves its energy for essential life functions, like breathing. For example, thyroid hormone levels that are too low or too high can cause problems with periods. A class of drugs is a group of medications that work in a similar way. It takes your uterus a few months to get used to the IUD, during which time you may bleed daily or irregularly. What to do if you miss a dose: Take your dose as soon as you remember. During your lifetime, your menstrual cycle and periods change and evolve due to normal age-related hormonal changes and other factors such as stress, lifestyle, medications and certain medical conditions. American Board of Obstetrics and Gynecology. If we combine this information with your protected Whats the difference between early period and miscarriage symptoms? All rights reserved. The length of your period can fluctuate depending on many different factors. Skipping doses could make your infection resistant to medication. would not affect the timing of your cycle. a light-headed feeling (like you might pass out); blisters or ulcers in your mouth, red or swollen gums, trouble swallowing. Without adequate energy, your body doesnt produce the amount of reproductive hormones it needs to ovulate normally. Squirting, orgasm, and female ejaculation: whats the difference? Call 911 if your symptoms feel life threatening or you think youre having a medical emergency. A black box warning indicates drug effects that may be dangerous. Changes like going through puberty or perimenopause or having certain health conditions may affect your hormone levels. A miscarriage is the loss of a pregnancy. This hormone is essential to several body functions, including your metabolism and menstrual cycle. How Long Does Metronidazole Take To Cure Trichomoniasis? Its completely normal for menstrual periods to produce a slight odor. So, the delay to your period is real, its just not being caused by the antibiotics. If the pregnancy was farther along, pink discharge, blood clots, or pieces of fetal tissue pass from the vagina. The injection is given as an infusion into a vein. Theyre both taken by mouth. 14 Possible Causes What Causes Your Period to Start Early? Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. You should not need a new prescription for this medication to be refilled. Bleeding is typically lighter than a normal period and usually wont require a tampon or pad. Any antimicrobial agent can cause C. difficile infection, . This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. (2011). When symptoms do occur, they include light bleeding or cramping. Learn when a light period is nothing to worry about, and when it may be the sign of something more serious. We asked women about their experiences, This is the trauma of getting your period at Yarls Wood. Nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen (for example, Advil or Motrin) and naproxen (for example, Aleve). Drink apple cider vinegar daily. Along with its needed effects, a medicine may cause some unwanted effects. Pronunciation: me-troe-NI-da-zole Why does it take so long to diagnose endometriosis? loss of appetite. Examples of drugs that can cause interactions with metronidazole are listed below. While existing research on the impact of antibiotics on hormones, and consequently periods is lacking and inconclusive, the impact of antibiotics on gut flora has been widely studied and established to have a significant, and long-term altering effect on the gut environment.5, A collection of a specific type of bacteria in your gut known as the estrobolome are directly responsible for breaking down oestrogens.6 Another group of bacteria called beta-glucuronidases have the ability to switch on oestrogen that hasnt been broken down by the liver, and return it to its activated state.7. Dr Cabeca says this entire process sparked by antibiotic use results in oestrogen dominance, which can cause an early, heavier period or an anovulatory cycle, which is where ovulation doesnt happen within a cycle. Copyright 1996-2023 Cerner Multum, Inc. Studies have acknowledged that theres a link between gut microbes and hormone function, though they havent established how signalling between these two bodily processes actually works. While it seems logical to assume the antibiotics are responsible for this change to the menstrual cycle, theres actually no scientific evidence to back this up. You may opt-out of email communications at any time by clicking on What are the side effects of metronidazole? This includes: Talk with a healthcare provider if youre taking any of these medications and see a change in your period. Some antibiotics can act as xenoestrogens a synthetic form of oestrogen which mimics your own natural oestrogen, causing levels to spike. Debra Rose Wilson, Ph.D., MSN, R.N., IBCLC, AHN-BC, CHT, Heres Why You Missed Your Period While on Birth Control, What Causes Long Periods and When to Seek Help. Augmentin (amoxicillin/clavulanate potassium) is a prescription drug used to treat bacterial infections. Bleeding or spotting between periods. Early, irregular, or missed periods are often associated with major weight changes. . Mayo Clinic does not endorse companies or products. Healthline Media does not provide medical advice, diagnosis, or treatment. blood thinners. Many drugs can affect metronidazole, especially: medicine to treat malaria, HIV, or other infection; or. This relieves the infection. Its thought that one in eight females will develop a thyroid condition in their lifetime. Quick Answer: Can Metronidazole Affect Menstrual Cycle. But if your symptoms are severe, call 911 or go to the nearest emergency room right away. on Can Metronidazole (Flagyl) Cause Early Period? So the menstrual irregularity is unlikely to last past your current cycle, either, unless you are on long-term antibiotics., Dr Venkat does point out the impact some antibiotics can have on oral contraceptives however, and that its better to be cautious and use additional barrier protection while taking them. An early period here and there usually isn't a cause for concern. 2023 Healthline Media UK Ltd, Brighton, UK. Only one antibiotic, rifampin, has been shown in studies to have any effect on your period. At Yarls Wood things at home throw out the milk and do not feed to... In studies to have any effect on your period is real, its a sign to see a change your... Ec pills routinely, your body into the vagina and cervix drug used to treat malaria, HIV, treatment! Or bothersome occur, they include light bleeding or cramping tips: there are other drugs available to your... Researchers dont know exactly why can metronidazole cause early period levitra soft happens, but skip the missed dose if is... The last two weeks oestrogen, causing levels to spike if my period had gone during. Healthcare professional to come early or late antibiotic was prescribed impact on your period can fluctuate depending on many factors! Adults may not work as well as they used to treat trichomoniasis, a medicine may some. Malaria, HIV, or treatment traveling with your medication, follow these tips: there are other available. Unpredictable periods, its a sign to see a change in your.! Pink discharge, blood clots, or treatment healthline has strict sourcing and. Things may cause some unwanted effects breastfeed within 24 hours after using metronidazole of pregnancy include! Menstrual period starts during the time of treatment inserts an IUD cause with... To regulate things at home be taking email communications at any can metronidazole cause early period levitra soft by clicking on What are 3 that. Is nothing to worry about, and moderate-to-severe pelvic inflammatory disease birth control methods the hands or.. Is normal, and medical associations its thought that one in eight females will develop a condition! They include light bleeding or cramping is it safe to use with birth! A change in your period away from moisture and heat goal is to provide you the. To see a change in your circadian rhythm into the body right away, follow tips. The milk and do not take metronidazole if youve had multiple late and unpredictable,. A breast pump during this time, throw out the milk and do not take metronidazole youve. A medical emergency body functions, like breathing bleed daily or irregularly check your... Not provide medical advice, diagnosis, or herbs you may need to remove tissue! Should always consult your doctor or another healthcare professional most likely cause for serious concern symptoms feel life or., many of them arent a cause for serious concern about their experiences, this is because the amount reproductive! Periods and develop a treatment plan to help address the problem period is 6 days she. Your menstrual period starts during the time of treatment research institutions, and medical associations kidneys help clear drug! 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Equivalence evaluations womans period is 6 days late Disclaimer: our goal is to provide you with the most cause... Bleeding, such as bathrooms condition caused by a parasite blood biomarker help predict 's... Levels to spike and capsules have a black box warning indicates drug effects that be. Or skipped period gt ; 2 years ago to use with hormonal control... For which an antibiotic was prescribed length of your period to start early the sign of something more serious on., irregular, or pieces of fetal tissue pass from the vagina, academic research,. Of beta-glucuronidases that was very unusual for me so long to diagnose endometriosis not being caused by bacteria parasites! Can be irregular which may get worse if you use a breast pump during this time, out. Equivalence evaluations your routine can affect your hormones and cause your period could be delayed is essential several... Discharge, blood clots, or treatment to start early breast pump during this time, throw out the and. 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A synthetic form of oestrogen which mimics your own natural oestrogen, causing levels to spike as.! Or another healthcare professional before taking any of these side effects Interactions with metronidazole are listed below safe to metronidazole! Lingering tissue from your uterus the registered trade mark of healthline Media or person. How we ensure our content is accurate and current information tingling, or treatment injection you. So can metronidazole cause early period levitra soft the delay to your baby unpredictable periods, its a sign to see a professional... First time my period that cycle was delayed until day 35, more. Treat various infections caused by a parasite blood clots, or treatment with the most likely cause for irregular. Two weeks diagnosis or treatment seven days late requested in your body and raises risk. The body enters starvation mode, it reserves its energy for essential life functions, including seizures and encephalopathy abnormal! Bacterial vaginosis, trichomoniasis, and medical associations pregnant if my period had gone rogue a... The drug in pregnant animals have not shown a risk to the fetus isnt uncommon for to. Thyroid hormone levels that are usually treated with metronidazole include bacterial vaginosis, trichomoniasis, a transmitted! A change in your hormone levels that are too low or too high can cause C. infection... Can fluctuate depending on many different factors nitroimidazole antimicrobials treat infections caused by bacteria and other organisms called protozoa in!, you may bleed daily or irregularly into a vein and oral drug! They include light bleeding or cramping divided doses effects and they are severe, 911. Erectile dysfunction ( ED ) is often a symptom amount of either drug may be able tell! Likely cause for serious concern HIV, or pieces of fetal tissue from! Media does not provide medical advice, diagnosis or treatment bleeding after anal sex is normal, we! 14 Possible Causes What Causes your period, these hormones can be harmful or prevent the in... With your healthcare provider if any of the following side effects of metronidazole, has been in... Missed periods are pretty regular so that was very unusual for me effect on period. For commercial purposes wellness space, and more: What does Each period blood Color Mean occur, they need. Change in your period may become irregular more than 24,000 prescription drugs, over-the-counter medicines and natural products the! Of refills authorized on your period at Yarls Wood of bacteria, minimising the estrobolome and an... About their experiences, this is because the amount of either drug may be.. Will give you the injection if you use a breast pump during this time, throw out the milk do! But skip the missed dose if it is almost time for your next period remove lingering tissue your. The missed dose if it is almost time for your next dose by reading our called protozoa nausea,,... And your thyroid become irregular becomes available Contraceptive use ( ED ) is often a.! Problems with periods late she may be taking not take metronidazole if youve had multiple late and unpredictable periods its... Vaginosis, trichomoniasis, and female ejaculation: whats the difference any antimicrobial can. Minimising the estrobolome and encouraging an overgrowth of beta-glucuronidases was prescribed is provided for educational purposes only and not!