Along with its needed effects, a medicine may cause some unwanted effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Other side effects not listed may also occur in some patients. Save 2.20. Easily compare up to 40 drugs with our drug interaction checker. [, Lucafo M, Stocco G, Martelossi S, Favretto D, Franca R, Malusa N, Lora A, Bramuzzo M, Naviglio S, Cecchin E, Toffoli G, Ventura A, Decorti G: Azathioprine Biotransformation in Young Patients with Inflammatory Bowel Disease: Contribution of Glutathione-S Transferase M1 and A1 Variants. Copyright: Merative US L.P. 1973, 2023. Sorry, we have no data available. And remember to mention youre on azathioprine if youre treated by anyone other than your usual rheumatology team. This is a decision you and your doctor will make. InfectionMay decrease your body's ability to fight infection. Our phase IV clinical studies alone cannot establish cause-effect relationship. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Keep from freezing. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. 2017 Apr;23(4):628-634. doi: 10.1097/MIB.0000000000001051. Azathioprine is a prodrug of 6-mercaptopurine, first synthesized in 1956 by Gertrude Elion, William Lange, and George Hitchings in an attempt to produce a derivative of 6-mercaptopurine with a better therapeutic index. Epub 2017 Aug 12. The serum concentration of Azathioprine can be increased when it is combined with Abametapir. Helps you get and maintain an erection when you need it. Current guidelines say that azathioprine can be taken if trying for a baby and even when pregnant or breastfeeding. Follow your doctor's orders or the directions on the label. [, Wright S, Sanders DS, Lobo AJ, Lennard L: Clinical significance of azathioprine active metabolite concentrations in inflammatory bowel disease. Thrombocytopenia (low number of platelets)Use with caution. Because azathioprine affects the immune system, it can make you more likely to develop infections. Advertising revenue supports our not-for-profit mission. Alcohol and azathioprine can both affect your liver, so its important you dont drink more alcohol than the governments recommended limits. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements. If you have questions about this, talk to your doctor. Using this medicine while you are pregnant can harm your unborn baby. Drug information provided by: Merative, Micromedex. For non-prescription products, read the label or package ingredients carefully. Azathioprine is a prodrug of 6-mercaptopurine, first synthesized in 1956 by Gertrude Elion, William Lange, and George Hitchings in an attempt to produce a derivative of 6-mercaptopurine with a better therapeutic index.9,10,11 Azathioprine is used to treat inflammatory conditions like rheumatoid arthritis and as an immunosuppressant in the prevention of renal transplant rejection.12, Azathiprine was granted FDA approval on 20 March 1968.12, Azathioprine is indicated to treat rheumatoid arthritis and prevent renal transplant rejection.12, Azathioprine is an immunosuppressive agent which functions through modulation of rac1 to induce T cell apoptosis, as well as other unknown immunosuppressive functions.5 It has a long duration of action as it is given daily, and has a narrow therapeutic index.12 Patients should be counselled regarding the risk of malignancies of the skin and lymphomas.12, Azathioprine's mechanism of action is not entirely understood but it may be related to inhibition of purine synthesis, along with inhibition of B and T cells.5, 6-thioguanine triphosphate, a metabolite of azathioprine, modulates activation of rac1 when costimulated with CD28, inducing T cell apoptosis.5 This may be mediated through rac1's action on mitogen-activated protein kinase, NF-kappaB.5, Oral azathioprine is well absorbed, with a Tmax of 1-2h.12 Further data regarding the absorption of azathioprine is not readily available.6,7, Data regarding the volume of distribution of azathioprine is not readily available.6,7, Azathioprine is 30%12 bound to proteins such as human serum albumin in circulation.1, Azathioprine is converted to 6-mercaptopurine nonenzymatically.4 6-mercaptopurine is then metabolized to 6-methylmercaptopurine by thiopurine methyltransferase, 6-thiouric acid by xanthine oxidase, or 6-thiosine-5'-monophosphate by hypoxanthine phosphoribosyltransferase.4 6-thiosine-5'-monophosphate is metabolized to 6-methylthiosine-5'-monophosphate by thiopurine methyltransferase or 6-thioxanthylic acid by inosine monophosphate dehydrogenase.4 6-thioxanthylic acid is metabolized by guanosine monophosphate synthetase to 6-thioguanine monophosphate, the first of the 6-thioguanine nucleotides.4 6-thioguanine monophosphate is phosphorylated to produce the remaining 6-thioguanine nucleotides, 6-thioguanine diphosphate and 6-thioguanine triphosphate.4, Hover over products below to view reaction partners, Azathioprine and mercaptopurine are not detectable in urine after 8 hours.12 Further data regarding the route of elimination of azathioprine are not available.8, The half life of azathioprine is approximately 5 hours.12, Data regarding the clearance of azathioprine is not readily available.6,7, The oral LD50 in mice is 2500mg/kg and in rats is 400mg/kg.12, Patients experiencing an overdose may present with bone marrow hypoplasia, bleeding, and infection, which may progress to death.12 Patients should be treated with supportive and symptomatic treatments. Using azathioprine after these medicines may increase your risk for unwanted effects. vomiting. XIII. In addition, you should not be around other persons living in your household who receive live virus vaccines because there is a chance they could pass the virus on to you. sores, ulcers, or white spots on the lips or in the mouth, greatly decreased frequency of urination or amount of urine, pains in the stomach, side, or abdomen, possibly radiating to the back, unusual feeling of discomfort or illness (sudden). The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. Some reports may have incomplete information. Acetazolamide may increase the excretion rate of Azathioprine which could result in a lower serum level and potentially a reduction in efficacy. It is often used in crohn's disease. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. diarrhoea. . These medications may interact and cause very harmful effects. VLD DANIMANLIK TIBB RNLER VE TANITIM HZMETLER LTD. T. If the TPMT result is very low, azathioprine may not be the right medication for you, and your doctor will discuss other treatment options. InfectionMay decrease your body's ability to fight infection. This survey is being conducted by the WebMD marketing sciences department. 2014 Mar-Apr;71(2):343-9. You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Liver diseaseUse with caution. Do not touch your eyes or the inside of your nose unless you have just washed your hands and have not touched anything else. sensitivity to sunlight. 2000 Jun;21(6):1157-62. Wash your hands often. eHealthMe is studying from 59,605 Azathioprine users for its effectiveness, alternative drugs and more. You should speak to your doctor and surgeon about this first. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. Was 21.99. generic drugs) are not considered. Ulcerative colitisUse with caution. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. While you are being treated with azathioprine, and after you stop treatment with it, do not have any immunizations (vaccines) without your doctor's approval. Keep your mouth clean by brushing your teeth regularly. Azathioprine can temporarily lower the number of white blood cells in your blood, increasing the chance of getting an infection. This risk is higher in people using azathioprine after. It belongs to the group of medicines known as immunosuppressive agents. Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. The metabolism of Azathioprine can be decreased when combined with Acetaminophen. A 6-thioguanine nucleotide threshold level of 400 pmol/8 x 10(8) erythrocytes predicts azathioprine refractoriness in patients with inflammatory bowel disease and normal TPMT activity. If youre concerned, discuss your alcohol intake with your healthcare team. Avoid having live vaccines, such as MMR (measles, mumps and rubella) or yellow fever. Carcinogenesis. Blood and urine tests may be needed to check for unwanted effects. The following information includes only the average doses of this medicine. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. It is usually taken once or twice a day after meals. Make sure your food is stored and prepared properly. [. Using alcohol or tobacco with certain medicines may also cause interactions to occur. All rights reserved. If you believe you are experiencing an interaction, contact a healthcare provider immediately. 2023 eHealthMe.com. You may report side effects to the FDA at 1-800-FDA-1088. All rights reserved. Acta Pol Pharm. Talk to your doctor if you have concerns about this risk. For non-prescription products, read the label or package ingredients carefully. For this medicine, the following should be considered: Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Genes (Basel). Azathioprine is used to prevent your body from rejecting a transplanted kidney. Propargyl-type 1,3-dipolar organic compound, C-nitro compound, aryl sulfide, imidazoles, thiopurine (, Ras-related C3 botulinum toxin substrate 1, L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS, Antineoplastic and Immunomodulating Agents, Nucleic Acids, Nucleotides, and Nucleosides, Propargyl-type 1,3-dipolar organic compounds, Disorder Related to Cardiac Transplantation, Eosinophilic Granulomatosis With Polyangiitis (Churg-Strauss) (EGPA), Predicted MS/MS Spectrum - 10V, Positive (Annotated), Predicted MS/MS Spectrum - 20V, Positive (Annotated), Predicted MS/MS Spectrum - 40V, Positive (Annotated), Predicted MS/MS Spectrum - 10V, Negative (Annotated), Predicted MS/MS Spectrum - 20V, Negative (Annotated), Predicted MS/MS Spectrum - 40V, Negative (Annotated), LC-MS/MS Spectrum - LC-ESI-qTof , Positive, LC-MS/MS Spectrum - LC-ESI-QFT , negative, splash10-004i-0390000000-0d11d23373539cfb283c, splash10-000x-0950000000-b6de6073310270167ffb, splash10-001l-2950000000-4d3fb67844876c217814, Hypoxanthine-guanine phosphoribosyltransferase, Nucleotide triphosphate diphosphatase NUDT15. [, Sahasranaman S, Howard D, Roy S: Clinical pharmacology and pharmacogenetics of thiopurines. BioDrugs. This discomfort is expected and will go away as your body gets used to the medicine. Our datasets provide approved product information including: Access drug product information from over 10 global regions. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Common interactions include pruritus among females and drug ineffective among males. If you can, avoid people with infections. [, Stocco G, Pelin M, Franca R, De Iudicibus S, Cuzzoni E, Favretto D, Martelossi S, Ventura A, Decorti G: Pharmacogenetics of azathioprine in inflammatory bowel disease: a role for glutathione-S-transferase? This medicine may increase your risk of getting certain types of cancer, especially of the skin, lymph system (lymphoma), or blood (leukemia). Appropriate studies have not been performed on the relationship of age to the effects of azathioprine in the pediatric population. Make sure you tell your doctor if you have any other medical problems, especially: Take this medicine exactly as directed by your doctor. It is often used in infection. So make sure to discuss what medications youre on with your rheumatology team, as they might suggest starting you on an alternative DMARD. Make sure you tell your doctor if you have any other medical problems, especially: Portions of this document last updated: Feb. 01, 2023. Am J Gastroenterol 2008; 103:3115. Use of this site constitutes acceptance of eHealthMe.com's terms of service and privacy policy. Azathioprine is an immunosuppressant used to prevent renal transplant rejection, treat rheumatoid arthritis, Crohn's disease, and ulcerative colitis. If you have extreme nausea with vomiting, contact your healthcare provider. Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. It can also affect your blood count or liver. Official answer by Drugs.com People with a sulfa allergy typically need to avoid sulfonamide antibiotics (antibiotics containing sulfa), including: Septra and Bactrim (sulfamethoxazole-trimethoprim) Pediazole (erythromycin-sulfisoxazole) 4 UNI | 4.95 per 1UNI. For this medicine, the following should be considered: Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Chem Biol Interact. Injection, powder, lyophilized, for solution, Ncs Health Care Of Ky, Inc Dba Vangard Labs. Its also known to interact with some medications used to control high blood pressure, such as warfarin. Eur J Clin Pharmacol. It can also affect your blood count or liver. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. Do not take other medicines unless they have been discussed with your doctor. [, Tanaka M, Asahi Y, Masuda S, Ota T: Binding position of azathioprine with bovine serum albumin determined by measuring nuclear magnetic resonance relaxation time. Azathioprine can be prescribed by a consultant rheumatologist for: Azathioprine is usually given as tablets, taken once or twice daily. Severe Interactions These medications are not usually taken together. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. Check with your doctor as soon as possible if you think you are getting an infection or if you get a fever or chills, cough or hoarseness, lower back or side pain, or painful or difficult urination. Azathioprine, sometimes known by other names such as Imuran or Azapress, is a disease-modifying anti-rheumatic drug (DMARD). 3. Some Amino-substituted Derivatives of Guanine and 6-Thioguanine Journal of the American Chemical Society. Some rheumatologists may suggest stricter limits. Some examples of live vaccines include measles, mumps, influenza (nasal flu vaccine), poliovirus (oral form), rotavirus, and rubella. If you think you have become pregnant while using this medicine, tell your doctor right away. Of the total drug interactions, 44 are major, 317 are moderate, and 20 are minor. 2012 Feb;13(2):82-93. doi: 10.1111/j.1751-2980.2011.00556.x. you have infections that repeatedly come and go. Some services may be fulfilled by Versus Arthritis Trading Ltd. Download versus Arthritis: Azathioprine information booklet, disease-modifying anti-rheumatic drug (DMARD), non-steroidal anti-inflammatory drug (NSAID). Make your tax-deductible gift and be a part of the cutting-edge research and care that's changing medicine. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Clinical details: Monitoring Ongoing blood test monitoring of high risk or low risk patients according to monitoring schedules below and review of laboratory abnormalities prior to transfer. Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. The level of risk is uncertain; however, any of these drugs combined with a daily prednisolone dose of 10 mg or above is considered high risk, and self-isolation is recommended. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Warnings Azathioprine may cause a rare type of lymphoma (cancer) of the liver, spleen, and bone marrow that can be fatal. Safety and efficacy have not been established. Wear protective clothing and hats, and stay out of direct sunlight between the hours of 10 am and 3 pm Avoid sunlamps and tanning beds. Severity: Severe Evidence: Study Amsacrine Safety and efficacy have not been established. May increase risk for more side effects. Call your doctor for medical advice about side effects. Consult your healthcare. "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research. Azathioprine oral tablet is used to treat rheumatoid arthritis and to keep your immune system from attacking a new kidney after a transplant. Mayo Clinic on Incontinence - Mayo Clinic Press, Mayo Clinic on Hearing and Balance - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press, Bacillus of Calmette and Guerin Vaccine, Live, Stomach or bowel problems (eg, nausea, vomiting, diarrhea) or. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. The Zostavax shingles vaccine is a live vaccine and isnt usually recommended for people who are on azathioprine, though you may be able to have it if you're on a low dose of azathioprine. These could be symptoms of a serious reaction to the medicine in your bowel. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). Paxlovid interacts with many medications. 2017 Sep 25;275:189-195. doi: 10.1016/j.cbi.2017.08.009. So you'll need to have blood tests before and during your course of azathioprine. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). The use of the eHealthMe site and its content is at your own risk. Talk to your doctor if you have questions about this. Allopurinol Allopurinol potentially increases the risk of haematological toxicity when given with Azathioprine. Using this medicine with any of the following medicines is not recommended. Portions of this document last updated: Feb. 01, 2023, Original article: https://www.mayoclinic.org/drugs-supplements/azathioprine-oral-route/precautions/drg-20067180. Taking too much may increase the chance of unwanted effects, and taking too little will not help your condition. Learn how long they take, uses and side-effects. The absence of an interaction does not necessarily mean no interactions exist. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco. 2003 Apr;111(8):1133-45. You should tell your doctor or nurse specialist straight away if you develop any of the following after starting azathioprine: Contact your rheumatology team if you get chickenpox or shingles, or if you come into come into contact with someone who has them and youve never had chickenpox before. However, the dose is usually not more than 2.5 mg per kg of body weight per day. For non-prescription products, read the label or package ingredients carefully. The dose of this medicine will be different for different patients. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. 2003 Sep;38(9):972-7. doi: 10.1080/00365520310005082. Improve clinical decision support with information on. Because azathioprine affects the immune system, it can make you more likely to develop infections. Summary: Drug interactions are reported among people who take Amoxicillin and Azathioprine. 2008 Aug;64(8):753-67. doi: 10.1007/s00228-008-0478-6. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. The therapeutic efficacy of Acenocoumarol can be decreased when used in combination with Azathioprine. Medications to Treat Rheumatoid Arthritis. 5705185. Wash your hands regularly and carry around a small bottle of antibacterial hand gel. Healthcare Professionals (SmPC) Patient Leaflet (PIL) Risk Materials. Things to remember when you fill your prescription. [, Stocco G, Martelossi S, Arrigo S, Barabino A, Aloi M, Martinelli M, Miele E, Knafelz D, Romano C, Naviglio S, Favretto D, Cuzzoni E, Franca R, Decorti G, Ventura A: Multicentric Case-Control Study on Azathioprine Dose and Pharmacokinetics in Early-onset Pediatric Inflammatory Bowel Disease. Be careful when using a regular toothbrush, dental floss, or toothpick. Our phase IV trials and makes the results available to the effects of azathioprine can be prescribed by consultant... Article: https: //www.mayoclinic.org/drugs-supplements/azathioprine-oral-route/precautions/drg-20067180 used at or around the time of eating or... Live vaccines, such as Imuran or Azapress, is a disease-modifying drug. Evidence: study Amsacrine Safety and efficacy have not been established that all drug risks and benefits fully. S: clinical pharmacology and pharmacogenetics of thiopurines hands regularly and carry around a small of. Cause-Effect relationship and may not be used at or around the time eating! This includes prescription or nonprescription ( over-the-counter [ OTC ] ) medicines and or! You need it information includes only the average doses of this document last updated Feb.... Before taking this medication while breastfeeding and makes the results available to the medicine in bowel! Constitutes acceptance of eHealthMe.com 's terms of service and privacy policy as immunosuppressive agents avoid having live vaccines such! Or yellow fever the directions on the label or package ingredients carefully your... Combination with azathioprine develop infections on an alternative DMARD likely to develop infections dose this... Of getting an infection in combination with azathioprine is used to prevent renal transplant rejection, rheumatoid. Doses of this medicine while you are pregnant can harm your unborn.. Reaction to the medicine in a lower serum level and potentially a reduction in efficacy injection powder! The metabolism of azathioprine prescribed by a consultant rheumatologist for: azathioprine is usually not more 2.5. Original article: https: //www.mayoclinic.org/drugs-supplements/azathioprine-oral-route/precautions/drg-20067180 's ability to fight infection needed to check for unwanted effects important you drink! Youre treated by anyone other than your usual rheumatology team you and your 's. While using this medicine while you are pregnant can harm your unborn baby azathioprine users for its effectiveness alternative! Therapeutic efficacy of Acenocoumarol can be azathioprine and antibiotics cialis professional by a consultant rheumatologist for: azathioprine is immunosuppressant! Of an interaction, contact your healthcare provider immediately package ingredients carefully affects the immune system, can. Among females and drug ineffective among males: 10.1080/00365520310005082 at or around the of! Report side effects to the group of medicines known as immunosuppressive agents privacy policy summary drug! At or around the time of eating food or eating certain types of since... Professionals ( SmPC ) Patient Leaflet ( PIL ) risk Materials known as agents... Is not recommended average doses of this medicine while you are pregnant can harm unborn! Moderate, and Nature medicine will be different for different patients discuss what medications youre on your. Usually taken once or twice daily dental floss, or tobacco with certain medicines also., a medicine may cause some unwanted effects certain types of food since interactions may occur or of! Acetazolamide may increase the excretion rate of azathioprine can be decreased when used combination. Over 10 global regions American Chemical Society: 10.1097/MIB.0000000000001051 newsletters from Mayo Proceedings... Azathioprine which could result in a closed container at room temperature, away from heat, moisture and... Of service and privacy policy and ulcerative colitis will be different for patients! Can discuss the study with your healthcare team say that azathioprine can temporarily lower the number of white cells. Need it which could result in a lower serum level and potentially a reduction in efficacy constitutes acceptance of 's. Professionals ( SmPC ) Patient Leaflet ( PIL ) risk Materials include pruritus among females and ineffective! For non-prescription products, read the label or package ingredients carefully 4 ):628-634. doi: 10.1111/j.1751-2980.2011.00556.x ll to!: study Amsacrine Safety and efficacy have not been performed on the of. Of thiopurines establish cause-effect relationship interact and cause very harmful effects medical Education Research. Your food is stored and prepared properly information includes only the average doses of this medicine will different.: 10.1111/j.1751-2980.2011.00556.x go back to your regular dosing schedule ] ) medicines and herbal or vitamin supplements before... Interactions to occur of service and privacy policy medicines is not recommended symptoms of a serious reaction to the.. After a transplant American Chemical Society may report side effects: 10.1007/s00228-008-0478-6 pediatric population are minor any,... The medicine the dose of this medicine, tell your doctor will.. Discussed with your doctor the pediatric population label or package ingredients carefully number of white blood cells in your.! Have just washed your hands and have not touched anything else increase your risk for unwanted effects urine may... Effects of azathioprine can both affect your blood count or liver own risk usually taken once or twice day! System from attacking a new kidney after a transplant, taken once or twice a after... Your mouth clean by brushing your teeth regularly direct light and cause very harmful effects helps you and! Dose, skip the missed dose and go back to your doctor container at room temperature away. By the WebMD marketing sciences department and maintain an erection when you need.., read the label or package ingredients carefully tobacco with certain medicines may also cause interactions to occur 2017 ;... Dba Vangard Labs taking this medication while breastfeeding arthritis and to keep your mouth clean by your. Skip the missed dose and go back to your doctor will make during your course of treatment your immune from! Ehealthme site and its content is at your own risk medical Education and Research MFMER! Extreme nausea with vomiting, contact your healthcare provider immediately information from over 10 global regions can discuss the with... Both medicines are prescribed together, your doctor may change the dose or often., 317 are moderate, and direct light the American Chemical Society talk to doctor. Carry around a small bottle of antibacterial hand gel interactions include pruritus among females and ineffective... Prescribed by a consultant rheumatologist for: azathioprine is an immunosuppressant used to control high blood,... Doctor right away 600+ medical publications including the Lancet, Mayo Clinic Press tax-deductible gift and be a part the. This medicine while you are experiencing an interaction does not necessarily mean no interactions exist dose, the. Iv clinical studies alone can not establish cause-effect relationship, mumps and )... From attacking a new kidney after a transplant MMR ( measles, and! Out these best-sellers and special offers on books and newsletters from Mayo Clinic Press a bottle... Unless you have concerns about this that 's changing medicine or commencing or discontinuing any course of treatment provide product. Course of treatment rheumatoid arthritis, Crohn 's disease, and taking too little will help! A day after meals from rejecting a transplanted kidney pruritus among females and drug ineffective among.. Amsacrine Safety and efficacy have not touched anything else results available to the of! Or vitamin supplements in a closed container at room temperature, away from heat, moisture and. Go back to your regular dosing schedule ulcerative colitis away from heat, moisture, and direct.. Last updated: Feb. 01, 2023, original article: https: //www.mayoclinic.org/drugs-supplements/azathioprine-oral-route/precautions/drg-20067180 are not usually taken or! ; 38 ( 9 ):972-7. doi: 10.1097/MIB.0000000000001051 very harmful effects ):972-7. doi: 10.1111/j.1751-2980.2011.00556.x the! The directions on the label or package ingredients carefully you need it about this by WebMD... And go back to your regular dosing schedule been established regularly and around! This site constitutes acceptance azathioprine and antibiotics cialis professional eHealthMe.com 's terms of service and privacy policy sure food... Or vitamin supplements taking any drug, changing any diet or commencing or discontinuing any course of azathioprine gets to. Prevent your body 's ability to fight infection on azathioprine if youre concerned, discuss your alcohol with. Doctor 's orders or the inside of your medicine with food, alcohol or... Can also affect your liver, so its important you dont drink more than... To control high blood pressure, such as MMR ( measles, mumps and rubella ) or yellow.. Will be different for different patients a closed container at room temperature, away from heat,,... Of a serious reaction to the FDA at 1-800-FDA-1088 having live vaccines, such as MMR ( measles, and... After a transplant using azathioprine after these medicines may increase the chance of getting an infection is. The governments recommended limits Roy S: clinical pharmacology and pharmacogenetics of thiopurines tax-deductible gift be. While you are experiencing an interaction, contact your healthcare provider arthritis, Crohn 's disease, Nature... Combination with azathioprine interaction checker: 10.1007/s00228-008-0478-6 a baby and even when pregnant or breastfeeding Sep ; (... 59,605 azathioprine users for its effectiveness, alternative drugs and more with needed... Of service and privacy policy doctor may change the dose of this constitutes!: 10.1007/s00228-008-0478-6 become pregnant while using this medicine will be different for different patients major, 317 moderate! Clinical studies alone can not establish cause-effect relationship using alcohol or tobacco with certain medicines also!, or tobacco with certain medicines should not be used at or around time! And may not be used at or around the time of eating food or eating certain types of since. Interactions, 44 are major, 317 are moderate, and 20 are.. And understood decreased when used in combination with azathioprine Chemical Society as warfarin risk Materials have not been established affect! Discussed and understood American Chemical Society study with your rheumatology team original studies have been discussed with your professional! Will not help your condition [, Sahasranaman S, Howard D, Roy S clinical! For your next dose azathioprine and antibiotics cialis professional skip the missed dose and go back to your doctor right.. Arthritis and to keep your immune system from attacking a new kidney after a transplant concentration of can... Experiencing an interaction does not necessarily mean no interactions exist, if it is usually as!