tepotinib will increase the level or effect of ondansetron by P-glycoprotein (MDR1) efflux transporter. indapamide and ondansetron both increase QTc interval. Consider dose reduction of sensitive P-gp substrates. Serious - Use Alternative (1)fingolimod and ondansetron both increase QTc interval. Avoid or Use Alternate Drug. Avoid or Use Alternate Drug. Contraindicated. Avoid or Use Alternate Drug. Monitor Closely (1)glecaprevir/pibrentasvir will increase the level or effect of ondansetron by P-glycoprotein (MDR1) efflux transporter. Get medical help right away if you develop some of the following symptoms: fast heartbeat, hallucinations, loss of coordination, severe dizziness, severe nausea/vomiting/diarrhea, twitching muscles, unexplained fever, unusual agitation/restlessness.A very serious allergic reaction to this drug is rare. Avoid with congenital long QT syndrome; ECG monitoring recommended with concomitant medications that prolong QT interval, electrolyte abnormalities, CHF, or bradyarrhythmias. Examples include street drugs such as MDMA/"ecstasy," St. John's wort, certain antidepressants (including SSRIs such as fluoxetine/paroxetine, SNRIs such as duloxetine/venlafaxine), among others. Avoid or Use Alternate Drug. Avoid or Use Alternate Drug. Avoid or Use Alternate Drug. Avoid with congenital long QT syndrome; ECG monitoring recommended with concomitant medications that prolong QT interval, electrolyte abnormalities, CHF, or bradyarrhythmias. Serious - Use Alternative (1)anagrelide and ondansetron both increase QTc interval. Minor (1)griseofulvin will decrease the level or effect of ondansetron by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Talk to your pharmacist for more details.Before using this medication, tell your doctor or pharmacist your medical history, especially of: irregular heartbeat, liver problems, stomach/intestinal problems (such as recent abdominal surgery, ileus).Ondansetron may cause a condition that affects the heart rhythm (QT prolongation). Avoid with congenital long QT syndrome; ECG monitoring recommended with concomitant medications that prolong QT interval, electrolyte abnormalities, CHF, or bradyarrhythmias. Minor/Significance Unknown. osimertinib and ondansetron both increase QTc interval. Contraindicated. Serious - Use Alternative (1)ondansetron, almotriptan. (1) nausea and vomiting associated with initial and repeat courses of moderately emetogenic cancer chemotherapy. No dosage adjustment for ondansetron is recommended for patients on these drugs. Either increases toxicity of the other by serotonin levels. ondansetron, fluoxetine. Consider reducing the dosage of P-gp substrates, where minimal concentration changes may lead to serious or life-threatening toxicities.Serious - Use Alternative (1)tucatinib will increase the level or effect of ondansetron by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. Avoid with congenital long QT syndrome; ECG monitoring recommended with concomitant medications that prolong QT interval, electrolyte abnormalities, CHF, or bradyarrhythmias. Use Caution/Monitor. A woman has told how she feared she'd never become a mum but gave birth to a boy at age 45 after taking Viagra to get pregnant.. Carin Rockind, 48, welcomed a "miracle" baby after trying to have a . Use Caution/Monitor. Then, the dose is 8 mg every 12 hours for 1 to 2 days. Avoid with congenital long QT syndrome; ECG monitoring recommended with concomitant medications that prolong QT interval, electrolyte abnormalities, CHF, or bradyarrhythmias.ondansetron, amoxapine. alfuzosin and ondansetron both increase QTc interval. etravirine will decrease the level or effect of ondansetron by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. ceritinib will increase the level or effect of ondansetron by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Avoid with congenital long QT syndrome; ECG monitoring recommended with concomitant medications that prolong QT interval, electrolyte abnormalities, CHF, or bradyarrhythmias. Avoid or Use Alternate Drug. Avoid or Use Alternate Drug. phenobarbital will decrease the level or effect of ondansetron by affecting hepatic/intestinal enzyme CYP3A4 metabolism. phenobarbital will decrease the level or effect of ondansetron by affecting hepatic enzyme CYP1A2 metabolism. information submitted for this request. cobicistat will increase the level or effect of ondansetron by affecting hepatic/intestinal enzyme CYP3A4 metabolism. CYP-450 inhibitors may decrease clearance of ondansetron. No dosage adjustment for ondansetron is recommended for patients on these drugs. levoketoconazole will increase the level or effect of ondansetron by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Generic name: ondansetron hydrochloride Dosage form: tablet Drug class: 5HT3 receptor antagonists Medically reviewed by Drugs.com. Avoid or Use Alternate Drug. Either increases toxicity of the other by serotonin levels. Avoid or Use Alternate Drug. Ivacaftor and its M1 metabolite has the potential to inhibit P-gp; may significantly increase systemic exposure to sensitive P-gp substrates with a narrow therapeutic index. This effect was not observed with istradefylline 20 mg/day. Alcohol or marijuana (cannabis) can make you more dizzy or drowsy. Avoid or Use Alternate Drug. Avoid with congenital long QT syndrome; ECG monitoring recommended with concomitant medications that prolong QT interval, electrolyte abnormalities, CHF, or bradyarrhythmias. Serious - Use Alternative (1)quinine and ondansetron both increase QTc interval. Modify Therapy/Monitor Closely. Use Caution/Monitor. Contraindicated. Monitor Closely (1)chloroquine increases toxicity of ondansetron by QTc interval. Avoid or Use Alternate Drug. Fexinidazole inhibits CYP3A4. Exercise extreme caution when vilanterol coadministered with drugs that prolong QTc interval; adrenergic agonist effects on the cardiovascular system may be potentiated. Avoid or Use Alternate Drug. Minor (1)zileuton will increase the level or effect of ondansetron by affecting hepatic enzyme CYP1A2 metabolism. Use Caution/Monitor. Avoid with congenital long QT syndrome; ECG monitoring recommended with concomitant medications that prolong QT interval, electrolyte abnormalities, CHF, or bradyarrhythmias. aripiprazole and ondansetron both increase QTc interval. Ondansetron is used to prevent nausea and vomiting that is caused by cancer medicines (chemotherapy) or radiation therapy. Serious - Use Alternative (1)ondansetron and thiothixene both increase QTc interval. Either increases toxicity of the other by serotonin levels. Avoid or Use Alternate Drug. If these effects last or get worse, tell your doctor promptly.To minimize dizziness and lightheadedness, get up slowly when rising from a sitting or lying position.Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Avoid coadministration of sensitive CYP3A4 substrates with ivosidenib or replace with alternative therapies. Minor/Significance Unknown. Avoid with congenital long QT syndrome; ECG monitoring recommended with concomitant medications that prolong QT interval, electrolyte abnormalities, CHF, or bradyarrhythmias. Serious - Use Alternative (1)aripiprazole and ondansetron both increase QTc interval. Serious - Use Alternative (1)fluconazole and ondansetron both increase QTc interval. Avoid or Use Alternate Drug. Modify Therapy/Monitor Closely. Avoid or Use Alternate Drug. Avoid or Use Alternate Drug. Avoid or Use Alternate Drug. Serious - Use Alternative (1)ondansetron and vorinostat both increase QTc interval. Avoid with congenital long QT syndrome; ECG monitoring recommended with concomitant medications that prolong QT interval, electrolyte abnormalities, CHF, or bradyarrhythmias. Maximum dose: 16 mg per dose Comments: Multi-day, single-dose administration of 24 mg orally for HEC has not been studied. Monitor Closely (1)amobarbital will decrease the level or effect of ondansetron by affecting hepatic/intestinal enzyme CYP3A4 metabolism. amitriptyline and ondansetron both increase QTc interval. Use Caution/Monitor. eribulin and ondansetron both increase QTc interval. Serious - Use Alternative (1)azithromycin and ondansetron both increase QTc interval. Avoid with congenital long QT syndrome; ECG monitoring recommended with concomitant medications that prolong QT interval, electrolyte abnormalities, CHF, or bradyarrhythmias. ondansetron and vemurafenib both increase QTc interval. Avoid or Use Alternate Drug. Monitor Closely (1)triptorelin increases toxicity of ondansetron by QTc interval. Avoid coadministration of fexinidazole with drugs known to block potassium channels or prolong QT interval.fexinidazole will increase the level or effect of ondansetron by affecting hepatic/intestinal enzyme CYP3A4 metabolism. asenapine transdermal and ondansetron both increase QTc interval. CYP-450 inhibitors may decrease clearance of ondansetron. ondansetron and saquinavir both increase QTc interval. Ask your healthcare professional how you should dispose of any medicine you do not use. letermovir increases levels of ondansetron by affecting hepatic/intestinal enzyme CYP3A4 metabolism. mitotane decreases levels of ondansetron by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. If concomitant use unavoidable, reduce the P-gp substrate dosage if recommended in its approved product labeling. topiramate will decrease the level or effect of ondansetron by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. Use Caution/Monitor. For oral dosage forms (oral disintegrating tablets, solution, or tablets): For prevention of moderate nausea and vomiting after treatment with cancer medicines: Adults and children 12 years of age and olderAt first, 8 milligrams (mg) taken 30 minutes before starting cancer treatment. Either increases effects of the other by QTc interval. Use Caution/Monitor. ondansetron, rizatriptan. Use Caution/Monitor. If coadministration is unavoidable, monitor patients for loss of therapeutic effect of these drugs. Avoid or Use Alternate Drug. Monitor Closely (1)tazemetostat will decrease the level or effect of ondansetron by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. Macimorelin causes an increase of ~11 msec in the corrected QT interval. fosphenytoin will decrease the level or effect of ondansetron by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. Avoid with congenital long QT syndrome; ECG monitoring recommended with concomitant medications that prolong QT interval, electrolyte abnormalities, CHF, or bradyarrhythmias. To prevent nausea after surgery, take ondansetron 1 hour before the start of surgery.Carefully follow your doctor's directions for taking this medication. Avoid with congenital long QT syndrome; ECG monitoring recommended with concomitant medications that prolong QT interval, electrolyte abnormalities, CHF, or bradyarrhythmias. Modify Therapy/Monitor Closely. Avoid or Use Alternate Drug. In addition to stomach bugs, Zofran might be prescribed for a child after having surgery if they are feeling nauseated from anesthesia. P-gp inhibitors may decrease clearance of ondansetron. This drug is available at a higher level co-pay. Serious - Use Alternative (1)ondansetron, selegiline. Serious - Use Alternative (1)amiodarone and ondansetron both increase QTc interval. Use Caution/Monitor. If unavoidable, reduce CYP3A substrate dose according to product labeling. Minor/Significance Unknown. For prevention of nausea and vomiting after radiation treatment: AdultsAt first, 8 milligrams (mg) taken 1 to 2 hours before radiation treatment. ChildrenUse and dose must be determined by your doctor. rucaparib will increase the level or effect of ondansetron by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Serious - Use Alternative (1)erythromycin stearate and ondansetron both increase QTc interval. QTc prolongation reported with higher than recommended doses of fostemsavir. ECG should be monitored closely. Serious - Use Alternative (1)ondansetron, imipramine. Serious - Use Alternative (1)haloperidol and ondansetron both increase QTc interval. Take this medication exactly as directed. Avoid or Use Alternate Drug. Avoid with congenital long QT syndrome; ECG monitoring recommended with concomitant medications that prolong QT interval, electrolyte abnormalities, CHF, or bradyarrhythmias. ondansetron, sertraline. Avoid with congenital long QT syndrome; ECG monitoring recommended with concomitant medications that prolong QT interval, electrolyte abnormalities, CHF, or bradyarrhythmias. Minor/Significance Unknown. Serious - Use Alternative (1)macimorelin and ondansetron both increase QTc interval. Zofran; Zofran ODT; Zuplenz; Descriptions. Either increases toxicity of the other by serotonin levels. Avoid or Use Alternate Drug. Use unavoidable, reduce CYP3A substrate dose according to product labeling affecting hepatic/intestinal enzyme metabolism... Associated with initial and repeat courses of moderately emetogenic cancer chemotherapy the cardiovascular system may be potentiated to. 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Prescribed for a child after having surgery if they are feeling nauseated from.! Effectiveness in the real world fosphenytoin will decrease the level or effect of by... Make you more dizzy or drowsy will increase the level or effect ondansetron!
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