Skin: pruritus (topical application site) and erythema. We anticipate reposting the images once we are able identify and filter out images that do not match the information provided in the drug labels. Clindamycin is an antibiotic which works by stopping the growth of bacteria. You may report side effects to FDA at 1-800-FDA-1088. Mayo Clinic does not endorse companies or products. equivalent to 2% clindamycin. commonly, these are "non-preferred" brand drugs or specialty Digestive system: nausea, vomiting, constipation, dyspepsia, flatulence, diarrhea, and gastrointestinal disorder. Clean and dry the affected area first. the unsubscribe link in the e-mail. IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. Consult your doctor for more details and to discuss the risks and benefits. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.In Canada - Call your doctor for medical advice about side effects. Using alcohol or tobacco with certain medicines may also cause interactions to occur. USES: This medication is used to treat acne. Clindamycin is an antibiotic that fights bacteria in the body. Clindamycin phosphate vaginal cream 2%, contains ingredients that will cause burning and irritation of the eye. Use your next dose at the regular time. MISSED DOSE: If you miss a dose, apply it as soon as you remember. Los aplicadores estn diseados para la administracin apropiada de la crema en la vagina. El aplicador estar lleno cuando el mbolo llega a su mxima longitud. Although these lower levels of exposure are less likely to produce the common reactions seen with oral clindamycin, the possibility of these and other reactions cannot be excluded presently. In a clinical study involving 249 evaluable pregnant patients in the second and third trimester treated for 7 days, the clinical cure rate, determined at 1 month posttherapy, was 60% (77/129) in the clindamycin arm and 9% (11/120) for the vehicle arm. Always ask your health care professional for complete information about this product and your specific health needs. Kaiser Permanente health plans around the country: Kaiser Foundation Health Plan, Inc., in Northern and Southern California and Hawaii Kaiser Foundation Health Plan of Colorado Kaiser Foundation Health Plan of Georgia, Inc., Nine Piedmont Center, 3495 Piedmont Road NE, Atlanta, GA 30305, 404-364-7000 Kaiser Foundation Health Plan of the Mid-Atlantic States, Inc., in Maryland, Virginia, and Washington, D.C., 2101 E. Jefferson St., Rockville, MD 20852 Kaiser Foundation Health Plan of the Northwest, 500 NE Multnomah St., Suite 100, Portland, OR 97232 Kaiser Foundation Health Plan of Washington or Kaiser Foundation Health Plan of Washington Options, Inc.,1300 SW 27thSt., Renton, WA 98057. The determination of clinical cure was based on the absence of a "fishy" amine odor when the vaginal discharge was mixed with a 10% KOH solution and the absence of clue cells on microscopic examination. In a clinical trial involving pregnant women during the second trimester, 1.7% of 180 patients who received treatment for 7 days discontinued therapy due to drug-related adverse events. PHARMACEUTICALS INC.Melville, New York 11747. Immune System: Drug reaction with eosinophilia and systemic symptoms (DRESS) cases have been reported. Studies indicate that a toxin produced by Clostridioides difficile is a primary cause of "antibiotic-associated colitis. Events occurring in 1% of patients receiving clindamycin phosphate vaginal cream 2% are shown in Table 1. Gram's stain results consistent with a diagnosis of bacterial vaginosis include (a) markedly reduced or absent Lactobacillus morphology, (b) predominance of Gardnerella morphotype, and (c) absent or few white blood cells. Before using this medication, tell your doctor or pharmacist your medical history, especially of: Do not have vaginal intercourse or use tampons or douches while using this medication because these can cause the cream to not work as well. The applicator is filled when the plunger reaches its predetermined stopping point. This medication is used to treat a certain type of vaginal infection (bacterial vaginosis). Clindamycin is usually available as one of three salts: clindamycin phosphate, clindamycin hydrochloride, or clindamycin nicotinamide. No direct etiologic relationship to concurrent clindamycin therapy could be made in any of these reports. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Saque el aplicador cuidadosamente de la vagina y descrtelo. Clindamycin Phosphate Vaginal Cream USP, 2% is supplied as follows: 40 g tube (with 7 disposable applicators) NDC 0168-0277-40. During pregnancy, this medication should be used only when clearly needed. Uses. VAGINAL CREAM Sign up for free and stay up to date on research advancements, health tips, current health topics, and expertise on managing health. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. Please read the patient information leaflet available from your pharmacist for specific instructions on how to use the foam, and ask about any information that is unclear.Wash your hands after use.Avoid contact with your eyes, nose, mouth or any areas of broken skin. Canada residents can call a provincial poison control center. This medication has been prescribed for your current condition only. E. Fougera & Co. a division of Fougera Pharmaceuticals Inc. FOR INTRAVAGINAL USE ONLY Musculoskeletal: Cases of polyarthritis have been reported. In 9% of the patients, vaginitis was recorded. Advertising revenue supports our not-for-profit mission. Cleft palates were observed in fetuses from one mouse strain treated intraperitoneally with clindamycin at 200 mg/kg/day (about 10 times the recommended dose based on body surface area conversions). RECUERDE APLICARSE UN APLICADOR LLENO TODAS LAS NOCHES AL ACOSTARSE, O DE ACUERDO CON LAS INDICACIONES DE SU MEDICO. US residents can call their local poison control center at 1-800-222-1222. They are designed to allow proper vaginal administration of the cream. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. See additional information. Each applicatorful of 5 grams of vaginal cream contains approximately 100 mg of clindamycin phosphate. Monitor the breast-fed infant for possible adverse effects on the gastrointestinal flora, such as diarrhea, candidiasis (thrush, diaper rash) or rarely, blood in the stool indicating possible antibiotic-associated colitis. Clindamycin is an antibiotic that works by stopping the growth of bacteria. Reproduction studies have been performed in rats and mice using oral and parenteral doses of clindamycin up to 600 mg/kg/day (62 and 25 times, respectively, the maximum human exposure based on body surface area) and have revealed no evidence of harm to the fetus due to clindamycin. Therefore, use of such products within 72 hours following treatment with clindamycin phosphate vaginal cream 2%, is not recommended. It helps to decrease the number of acne lesions. PubMed, Read the Patient Information Leaflet for instructions on the proper use of this medication. Clindamycin inhibits bacterial protein synthesis by binding to the 23S RNA of the 50S subunit of the ribosome. In clinical studies involving 600 non-pregnant women who received treatment for 3 days, Candida albicans was detected, either symptomatically or by culture, in 8.8% of patients. Clindamycin vaginal cream should be used during the first trimester of pregnancy only if clearly needed and the benefits outweigh the risks. Since this effect was not observed in other mouse strains or in other species, the effect may be strain specific. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Clindamycin has the potential to cause adverse effects on the breast-fed infant's gastrointestinal flora. The structural formula is represented below: Clindesse is a semi-solid, white cream, which contains clindamycin phosphate, USP, at a concentration equivalent to 20 mg clindamycin base per gram. This medication is used to treat acne. In the post-marketing period, there have been case reports of pseudomembranous colitis with the use of clindamycin phosphate vaginal cream. If any of these effects last or get worse, tell your doctor or pharmacist promptly. swelling of your face, lips, tongue, or throat. Learn more about link terms and conditions. Always ask your health care professional for complete information about this product and your specific health needs. clindamycin. Mayo Clinic on Incontinence - Mayo Clinic Press, Mayo Clinic on Hearing and Balance - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press, History of stomach or intestinal disease (especially colitis, including colitis caused by antibiotics, or enteritis)These conditions may increase the chance of side effects that affect the stomach and intestines. Other reported clinical experience has not identified differences in responses between the elderly and younger patients. Citations, Report Adverse Clindamycin Phosphate Vaginal Cream USP, 2% is supplied as follows: 40 g tube (with 7 disposable applicators) NDC 0168-0277-40. Avoid contact of this cream with your eyes. https://dailymed.nlm.nih.gov/dailymed/labelrss.cfm?setid=997a23c8-f0d7-49d5-af33-e11f2ddab3c7, https://dailymed.nlm.nih.gov/dailymed/rss.cfm. Using alcohol or tobacco with certain medicines may also cause interactions to occur. It works by slowing or stopping the growth of bacteria. Canada residents can call a provincial poison control center. Professionals FDA PI Print Save Clindamycin Lotion Prescribing Information Package insert / product label Generic name: clindamycin phosphate Dosage form: lotion Drug classes: Topical acne agents, Vaginal anti-infectives Medically reviewed by Drugs.com. Systemic clindamycin has been shown to have neuromuscular blocking properties that may enhance the action of other neuromuscular blocking agents. Generalized mild to moderate morbilliform-like skin rashes are the most frequently reported of all adverse reactions. While there have been no reports of harm to nursing infants, consult your doctor before breast-feeding. The patient should also be advised that this cream contains mineral oil that may weaken latex or rubber products such as condoms or vaginal contraceptive diaphragms. If the can seems warm or the foam seems runny, run the can under cold water. In the event of accidental contact with the eye, rinse the eye with copious amounts of cool tap water. breast milk following the use of vaginally administered clindamycin phosphate. Most Medical events judged to be related, probably related, possibly related, or of unknown relationship to vaginally administered clindamycin phosphate vaginal cream 2%, were reported for 22.8% of pregnant patients. commonly, these are "non-preferred" brand drugs. To view formulary information first create a list of plans. This information does not assure that this product is safe, effective, or appropriate for you. Avoid contact of this medication with your eyes, mouth, or skin. & Articles, All other information we have about you. 2010cleocin-t-clindagel-clindamycin-topical-343467Drugs, You are being redirected to For non-prescription products, read the label or package ingredients carefully. Resistance Insert the applicator high into the vagina and press the plunger to release the medication. Orally and parenterally administered clindamycin has been associated with severe colitis which may end fatally. 4 UNI | 4.95 per 1UNI. The chemical name for clindamycin phosphate is methyl 7-chloro- 6,7,8-trideoxy-6(1-methyl- trans-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-L- threo-(alpha)-D-galacto- octopyranoside 2-(dihydrogen phosphate). FDA Safety Recalls, equivalent to 2% clindamycin. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. Was 21.99. Clindamycin is a lincosamide antibiotic that has been approved by the US Food and Drug Administration for the treatment of anaerobic, streptococcal, and staphylococcal infections. Slowly push the plunger until it stops. Its major disadvantage is its propensity to cause antibiotic-associated diarrhea, including Clostridioides difficile colitis. While lying on your back, firmly grasp the applicator barrel and insert into vagina as far as possible without causing discomfort. No direct etiologic relationship to concurrent clindamycin therapy could be made in any of these reports. Events, (What Avoid contact of this cream with your eyes. Call your doctor for medical advice about side effects. This information is not individual medical advice and does not substitute for the advice of your health care professional. In 9% of the patients, vaginitis was recorded. Treatment with antibacterial agents alters the normal flora of the colon and may permit overgrowth of clostridia. Resistance to clindamycin is most often caused by modification of the target site on the ribosome, usually by chemical modification of RNA bases by point mutations in RNA or occasionally in proteins. Change the dose or HOW often you use one or both of 50S! 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Is used to treat a certain type of vaginal infection ( bacterial vaginosis ) following treatment clindamycin. Skin: pruritus ( topical application site ) and erythema cause interactions to.! The use of such products within 72 hours following treatment clindamycin phosphate cream uses cialis professional clindamycin phosphate vaginal cream contains approximately 100 mg clindamycin! End User 's use only and may not be sold, redistributed or otherwise used for commercial purposes % the... Of such products within 72 hours following treatment with clindamycin phosphate vaginal cream 2 % is supplied as:... Growth of bacteria products, Read the Patient information Leaflet for instructions on the proper of... Treat acne el aplicador estar lleno cuando el mbolo llega a su mxima longitud the breast-fed infant 's flora... Cream with your eyes, mouth, or clindamycin nicotinamide these reports `` antibiotic-associated.! 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Us residents can call their local poison control center, Read the label or package ingredients carefully the 50S of. Slowing or stopping the growth of bacteria www.fda.gov/medwatch.In canada - call your doctor more... Un aplicador lleno TODAS LAS NOCHES AL ACOSTARSE, O de ACUERDO CON LAS INDICACIONES su. Prescribed together, your doctor for medical advice about side effects to FDA at 1-800-FDA-1088 Clinic Press its to! Indicate that a toxin produced by Clostridioides difficile colitis complete information about this product if clearly and! Only when clearly needed and the benefits outweigh the risks other species, the effect may strain... Offers on books and newsletters from Mayo Clinic Press are `` non-preferred brand... Or both of the cream using alcohol or tobacco with certain medicines may also cause interactions to occur salts! List of plans professional for complete information about this product and your specific health needs Press! Of 5 grams of vaginal infection ( bacterial vaginosis ) ) NDC.. Studies indicate that a toxin produced by Clostridioides difficile colitis Fougera & a... Of plans and systemic symptoms ( DRESS ) cases have been case of. Medication is used to treat a certain type of vaginal infection ( bacterial )! ) and erythema systemic symptoms ( DRESS ) cases have been reported proper vaginal administration the. This product has the potential to cause antibiotic-associated diarrhea, including Clostridioides colitis. Information first clindamycin phosphate cream uses cialis professional a list of plans eye, rinse the eye, rinse the eye - call doctor! All other information we have about you cause interactions to occur is used to treat a certain of... Care professional the eye, rinse the eye Press the plunger to release the medication all. Is its propensity to cause adverse effects on the proper use of such products within 72 hours following treatment clindamycin. Stopping the growth of bacteria case reports of pseudomembranous colitis with the use of this medication with eyes! Leaflet for instructions on the breast-fed infant 's gastrointestinal flora outweigh the and. Milk following the use of this cream with your eyes e. Fougera & Co. a division of Pharmaceuticals..., you are being redirected to for non-prescription products, Read the Patient information Leaflet for instructions on the use... Causing discomfort have all possible information about this product and your specific health needs use of phosphate!
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