The following foods may be helpful: You can also try limiting caffeine and alcohol. It lets doctors and patients know about a drugs effects that may be dangerous. This is to reduce the risk of side effects from the statin. your healthcare provider will do blood What you need to know before you take Epclusa 3. Dosage for chronic hepatitis C. Epclusa's recommended dosage for hepatitis C in adults is one 400 mg/100 mg tablet or two 200 mg/50 mg packets of pellets once per day, for 12 weeks. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. www.fda.gov/medwatch If youre uncertain about what to do about a missed dose, call your doctor or pharmacist. Its a place where people with certain conditions can find support and connect with others. You may report side effects to FDA at 1-800-FDA-1088. Theyll check for signs of muscle breakdown. Be sure to read on for more details. EPCLUSA, treatment with EPCLUSA. including liver No. Females who take Epclusa in combination with ribavirin should avoid becoming pregnant during treatment and for 6 months after stopping treatment. pharmacist about all the medicines you take. Slow heart rate (To learn whether Epclusa interacts with supplements, herbs, and vitamins, see the Are there other interactions with Epclusa? section below.). effects They can recommend the best time of day to take Epclusa to reduce your risk of interactions. Learn about the test and what it can tell you. In some cases slow heart rate has led to death or the need for a pacemaker when How long you take this medication depends on the severity of your condition and how you respond to treatment. provider or pharmacist. (If you take an H2-blocker besides famotidine, your doctor may prescribe a lower dose of that drug as well.). You should always consult your doctor or another healthcare professional before taking any medication. are breastfeeding or plan to breastfeed. Below are answers to some commonly asked questions about Epclusas dosage. How Do I Manage the Side Effects of Treating Hep C? and requested verification of your insurance coverage, you will receive verification of your benefits in You can also sprinkle the pellets on a non-acidic food such as pudding or ice cream. Talk with your doctor if you experience side effects that dont go away or are bothersome while taking Epclusa. If you take a statin, they may lower your statin dosage during your Epclusa treatment. Slow heart rate (bradycardia): Your doctor will continue to monitor your liver after you stop taking Epclusa. When it comes to Hepatitis A and B, there are vaccines to protect against the infections, Of all the different forms of hepatitis, a Hepatitis C diagnosis may have the greatest impact on your life, A, B and C are three of the different types of hepatitis, Some forms are acute and go away on their own. inhibitors are a class of antiviral drugs used to treat Hep C and work by stopping the virus from Liver problems other than hepatitis C. Be sure to tell your doctor if you have severe liver problems before starting Epclusa. However, this side effect wasnt reported in clinical trials. If you have kidney problems, be sure to tell your doctor. In clinical trials of Epclusa, nausea was commonly reported. Epclusa (sofosbuvir and velpatasvir) tablets, for oral use; Epclusa (sofosbuvir and velpatasvir) oral pellets. Select a condition to view a list of medication options. EPCLUSA? Dont stop taking EPCLUSA without first talking with your healthcare provider. if youre currently taking any medication to treat your addiction, such as methadone, a medication-assisted treatment for addiction. Keep in mind that this table does not include all drugs that may interact with Epclusa. Get medical help right away if you take amiodarone with Epclusa and get any of the following symptoms: The most common side effects of EPCLUSA include headache and tiredness. Remember, you should not change your dosage of Epclusa without your doctors recommendation. Examples include: Taking certain seizure medications with Epclusa can decrease the level of Epclusa in your body. These articles might help: Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. chronic infection of genotype 6 hepatitis C virus, chronic infection of genotype 1 hepatitis C virus, chronic infection of genotype 2 hepatitis C virus, chronic infection of genotype 3 hepatitis C virus, chronic infection of genotype 4 hepatitis C virus, chronic infection of genotype 5 hepatitis C virus. Consuming grapefruit products with Epclusa may cause the drug to build up in your body, which can raise your risk of side effects. EPCLUSA is a prescription medicine used to treat adults with chronic (lasting a long time) Before taking Epclusa, tell your healthcare provider about all of your medical conditions, including if you: Tell your healthcare provider about all of the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. death. However, drinking large amounts of alcohol can worsen hepatitis C, which Epclusa is used to treat. How Much Blood Is Needed to Transmit Hepatitis C? How to take Epclusa 4. If your blood sugar becomes too low, your doctor may lower the dosage of your diabetes medication or have you temporarily stop taking it. It may harm them. Epclusa is used in children ages 3 years and older. The most common side effects of EPCLUSA in adults include headache and tiredness. If you have trouble opening medication bottles, let your pharmacist know. 400 milligrams (mg) sofosbuvir and 100 mg velpatasvir. Do not take Epclusa If you are allergic to sofosbuvir, velpatasvir or any of the other ingredients of this medicine (listed in section 6 of this leaflet). 1-855-7-MYPATH Symptoms can be mild or serious and can include: For mild symptoms of an allergic reaction, call your doctor right away. EPCLUSA can cause serious side Why is it important to stay on EPCLUSA for the full course of treatment? EPCLUSA. Mavyret vs. Epclusa: How These Drugs Compare, Epclusa vs. Harvoni: What You Should Know, sites.psu.edu/cannabinoid/files/2020/06/Cannabinoid-as-PRECIPITANT-Medication-Affecting-the-Metabolism-of-ANOTHER-OBJECT-Medication_04_25.pdf, accessdata.fda.gov/drugsatfda_docs/label/2022/208341s019lbl.pdf, sites.psu.edu/cannabinoid/files/2020/06/NTI-Meds-to-be-Closely-Monitored-when-Co-Administered-with-Cannabinoids_2020_04_25.pdf, Hepatitis C Treatment: What a Liver Transplant Means for You. It may be taken alone or in combination with ribavirin (an antiviral) in certain cases. Its important to take EPCLUSA as prescribed by your healthcare provider. should know about EPCLUSA? Tell your healthcare provider and Possible side effects 5. This drug has a boxed warning for the risk of reactivation of hepatitis B virus. (1-855-769-7284)to see what For information on the expiration, storage, and disposal of Epclusa, see this article. How Much Does Treatment for Hepatitis C Cost? * This pellet strength is only prescribed for children based on their weight. medicines, vitamins, and herbal supplements. This article answers common questions about how hepatitis C is transmitted and ways to avoid transmission. Visit Epclusa may cause several side effects. Do not take more Epclusa than your doctor prescribes as this can lead to serious side effects. You can take . Sofosbuvir and velpatasvir are antiviral medications that prevent hepatitis C virus (HCV) from multiplying in your body. This article answers common questions about how hepatitis C is transmitted and ways to avoid transmission. Whether you drink alcohol or use cannabis. Call your healthcare provider right away if you think you may be pregnant or become pregnant during treatment with Epclusa in combination with ribavirin. Taking Epclusa exactly as prescribed can also help prevent interactions. at least 3 months after treatment is completed. How do I find out if my insurance covers EPCLUSA? Medicines are sometimes prescribed for purposes other than those listed in a Patient Information guide. Learn. C patients who had previously failed a During a crisis, people who are hard of hearing can use their preferred relay service or dial 711 then 988. All rights reserved. Store EPCLUSA at room temperature below 86 F (30 C), Do not use EPCLUSA if the seal over the bottle opening is broken or missing. Sharing this information with them may help prevent possible interactions. of your medical conditions, including if you have ever had hepatitis B infection, liver problems Esomeprazole (Nexium), lansoprazole (Prevacid), rabeprazole (Aciphex), and pantoprazole (Protonix) have not been studied with Epclusa. These medications may interact and cause very harmful effects. We link primary sources including studies, scientific references, and statistics within each article and also list them in the resources section at the bottom of our articles. If you develop a side effect while taking Epclusa and want to tell the FDA about it, visit MedWatch. known if EPCLUSA will harm your unborn baby or pass into your breast milk. Introductory Offer: Save 10 percent on Cialis Together 4 pack - online only. What is the most important information I should know about Epclusa? The most common types of viral hepatitis are A, B, and C. They all affect the liver and have similar symptoms, but transmission and treatments differ, People may not experience any symptoms of hepatitis C infection. Examples of these side effects include muscle pain and muscle breakdown. EPCLUSA is a prescription medicine used to treat adults with chronic (lasting a long time) 2005 - 2023 WebMD LLC, an Internet Brands company. genotype 1-6 infection with or without cirrhosis Want to talk to a person instead? your visit and bring it with you. You can ask your healthcare provider or pharmacist for a list of medicines that interact with Epclusa. You should also tell them about any HIV drugs you take. If youve had an allergic reaction. healthcare Mild side effects that have been reported with Epclusa include: These side effects may be temporary, lasting a few days to weeks. information I should know about could healthcare provider will monitor you This is because taking the drug could cause another allergic reaction. In clinical trials, children ages 6 years and older who took Epclusa had similar side effects to adults. Active ingredients: sofosbuvir and velpatasvir. You should not take Epclusa with ribavirin if youre pregnant or planning to become pregnant. These side effects may be temporary, lasting a few days to weeks. If taking H2-receptor antagonists (used for heartburn), take Epclusa at the same time or separate by 12 hours at a dose that does not exceed doses comparable to famotidine 40 mg twice per day. But treatment can cause side effects. when amiodarone is taken with medicines containing sofosbuvir. MNT is the registered trade mark of Healthline Media. including hepatitis B virus reactivation: Slow heart rate Hepatitis C is a viral infection that causes inflammation of the liver. vitamins, and herbal supplements. Take Epclusa exactly as prescribed by your doctor to ensure the drug keeps working to treat your condition. * An active ingredient is what makes a drug work. Protease There is no known interaction between Epclusa and alcohol. Tell your healthcare provider about all of your This happened in people who were not being treated for HBV. Do not give Epclusa to other people, even if they have the same symptoms you have. Drinking alcohol with Epclusa may increase your risk of certain side effects, including: Alcohol may also worsen liver problems such as cirrhosis. If the side effects seem life threatening or you think youre having a medical emergency, immediately call 911 or your local emergency number. Talk with your doctor if you are pregnant or can become pregnant. How to store Epclusa 6. This can make Epclusa less effective. See complete Important SafetyInformation Your doctor may prescribe another drug with Epclusa to treat your hepatitis C. Allergic reaction. This can make Epclusa less effective. EPCLUSA is a prescription medicine used to treat adults and children 3 years of age and older with chronic (lasting a long time) hepatitis C virus (HCV) genotype 1, 2, 3, 4, 5, or 6 infection: without cirrhosis or with compensated cirrhosis. Epclusa (sofosbuvir and velpatasvir) is a prescription drug used to treat hepatitis C. This drug can interact with alcohol, other medications, and some supplements. Speak with your healthcare provider to find out if EPCLUSA is right for you. Note that the information below does not include all other possible interactions with Epclusa. Does the dosage of Epclusa depend on other medications Im taking. Serious side effects that have been reported and their symptoms include: * Epclusa has a boxed warnings for this side effect. Regardless of how you take famotidine, you should not take more than 40 milligrams (mg) of famotidine twice per day while taking Epclusa. Last updated on Jun 28, 2022. Epclusa contains two active ingredients: sofosbuvir and velpatasvir. Some people taking these kinds of medications with Epclusa experienced serious heart rate problems and needed a pacemaker or other interventions. Some of Epclusas side effects may be mild and go away after a few days. Theyll likely have you monitor your blood sugar more closely while youre taking Epclusa. People who have both hepatitis C virus (HCV) and HBV infections can have reactivation of HBV. Because of this, taking Epclusa with acid-reducing drugs can make it more difficult for Epclusa to dissolve in your stomach. Epclusa (sofosbuvir and velpatasvir) is a prescription drug thats used to help treat hepatitis C. It comes as tablets and oral pellets and is usually taken once per day. If you have questions about your Epclusa dosage, ask your doctor or pharmacist for more information. EPCLUSA and certain other medicines may affect each other, or The content on this site is intended for US residents only. If you take HIV medications that interact with Epclusa, your doctor may recommend a treatment option other than Epclusa for your hepatitis C. Pregnancy. Our website services, content, and products are for informational purposes only. They may recommend medications, such as acetaminophen (Tylenol) or ibuprofen (Advil, Motrin), to help with pain relief. Epclusa is not known to cause long-term side effects. This could cause the statin to build up in your body, which may increase your risk of side effects from the statin. You still might be eligible for financial assistance. These medications may cause some risk when taken together. For more information, call 1-800-445-3235 or go to www.epclusa.com. $5 per co-pay. Epclusa contains a combination of sofosbuvir and velpatasvir. Virus reactivation: slow heart rate hepatitis C is transmitted and ways to avoid.! Go away after a few days to weeks and want to tell your healthcare provider and possible effects... Of your this happened in people who were not being treated for HBV, visit.. Or ibuprofen ( Advil, Motrin ), to help with pain relief of alcohol can worsen hepatitis C (... Be dangerous medication-assisted treatment for addiction: you can ask your healthcare provider and possible effects... 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