With around 52,000 team members and over 2,200 stores, ranging from local community pharmacies to large destination health and beauty stores, Boots serves its customer and patients wellbeing for life. Patients on low sodium diets can be informed that this medicinal product is essentially 'sodium-free'. In some cases, foods that contain a lot of fat can cause Viagra Connect to take longer to work. You know perfectly well what's good and what isn't good for you. Efficacy was assessed by means of diaries used to capture details of each sexual event, and a sexual function questionnaire (now known as the International Index of Erectile Function) IIEF. Viagra (generic name sildenafil) is a drug used in the treatment of erectile dysfunction, also known as impotence. In a study of healthy male volunteers, co-administration of the endothelin antagonist, bosentan, (an inducer of CYP3A4 [moderate], CYP2C9 and possibly of CYP2C19) at steady state (125 mg twice a day) with sildenafil at steady state (80 mg three times a day) resulted in 62.6% and 55.4% decrease in sildenafil AUC and Cmax, respectively. In some cases, Viagra Connect can lead to drowsiness, dizziness and other visual problems that might impair your ability to operate machinery or drive a car. Viagra Connect will only be available in one dosage: 50mg. Because Viagra and Viagra Connect both contain sildenafil, they work in the same way. If this happens, stop taking your treatment and seek emergency help. This medication works by increasing blood flow to the penis and groin by relaxing the blood vessels in your body. Your prescription will be issued by one of our in-house doctors who are all registered with the Irish Medical Council. Pharmacokinetic analysis of clinical trial data indicated a reduction in sildenafil clearance when co-administered with CYP3A4 inhibitors (such as ketoconazole, itraconazole, erythromycin, cimetidine). If you find out that Viagra Connect is not appropriate for you, your medical professional will be able to provide advice on another substance that you can use which will be safer. Empowering people and promoting diversity, You are here: Home Make sure that you do not use this medication and drive unless you feel safe to do so. If you have been taking prescription Viagra you should be able to safely transition to Viagra Connect, provided you have been taking a dosage of 50mg. When taking medications for erectile dysfunction, make sure that you speak to your doctor or seek emergency help if you experience a painful or prolonged erection for four hours or more. Find out what they think about the most important issues of the day from healthcare equality to sustainability. The safety and efficacy of sildenafil was maintained in long term studies. This first-of-its-kind launch included an extensive training program for pharmacists to help them assess and recommend treatment. Our pharmacies are very busy at the moment, so we recommendchoosing delivery at checkout. 100mg. Viagra (sildenafil) is a brand-name prescription drug that's used to treat erectile dysfunction (ED). Sildenafil is an oral therapy for erectile dysfunction. The postulated mechanism for this change in colour discrimination is related to inhibition of PDE6, which is involved in the phototransduction cascade of the retina. Effects of sildenafil on other medicinal products. Nicorandil is a hybrid of potassium channel activator and nitrate. This product is not intended for men under 18 years of age. In some patients, the use of VIAGRA with alpha-blockers can lead to a drop in blood pressure or to fainting. Like Viagra, Viagra Connect will only help you last longer in bed if youre losing your erections partway through having sex. If you are currently taking a higher or lower dosage of Viagra or Sildenafil, you should talk to your doctor before switching over to the Viagra Connect. All the following results with sildenafil 50 mg were also clinically and statistically significantly different from placebo unless otherwise stated. Alpha-blockers are sometimes prescribed for prostate problems or high blood pressure. Each 50 mg tablet contains 1.7 mg lactose (as monohydrate). By making it easier to obtain Viagra in a pharmacy, men with ED will have safe access to the medicine they need, and the opportunity to discuss their health problems with a medical professional. This medication can react poorly in some people, particularly those with heart conditions, and it is dangerous to take Viagra Connect without the approval of your doctor. The N-desmethyl metabolite is further metabolised, with a terminal half life of approximately 4 h. The total body clearance of sildenafil is 41 L/h with a resultant terminal phase half life of 3-5 h. After either oral or intravenous administration, sildenafil is excreted as metabolites predominantly in the faeces (approximately 80% of administered oral dose) and to a lesser extent in the urine (approximately 13% of administered oral dose). After oral dosing of sildenafil AUC and Cmax increase in proportion with dose over the recommended dose range (25-100 mg). VIAGRA connect Available Without a Prescription from Today. For payment purposes Healthrock Ltd., 11-12 St. James's Square, London, United Kingdom, SW1Y 4LB, registration number 09056454 can be used. Consistent with its known effects on the nitric oxide/cGMP pathway (see section 5.1), sildenafil was shown to potentiate the hypotensive effects of nitrates, and its co-administration with nitric oxide donors or nitrates in any form is therefore contraindicated (see section 4.3). Despite increasing awareness about the condition, many men still feel embarrassed about visiting a doctor to discuss the problem and seek treatment. Most people will not experience any dangerous side effects when taking Viagra Connect. Read the views of our team members at Boots, who are experts in their field. Sildenafil has vasodilator properties, resulting in mild and transient decreases in blood pressure (see section 5.1). The active ingredient of this medication is sildenafil, which is also available in its generic form. Learn about side effects, warnings, dosage, and more. Nothing on this website is an offer by Dokteronline. However some men only reported improvements after several (up to 8) doses (78.4% for 50 mg and 46.7% for placebo). The first thing to know about Viagra Connect is that it contains the same active ingredient as Viagra, sildenafil citrate. Why is Viagra Connect being made available over the counter? Viagra Connect is a treatment for sexual function problems in men, and is typically used to increase blood flow in the penis. Healthcare professionals are asked to report any suspected adverse reactions via the Yellow Card Scheme at www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store. Were here Mon-Fri, 9am to 6pm, Sat 9am to 5pm. Their answers will be checked over by a pharmacist before they receive the product. This first-of-its-kind launch included an extensive training program for pharmacists to help them assess and recommend treatment. It will be available in pharmacy and online from Boots exclusively for a two-week period, prior to being made available from wider pharmacies. In this study men taking sildenafil 50 mg 30 minutes to one hour prior to sexual activity reported improved quality of erections and satisfaction with sexual experience, improved relationship with partner, improved confidence and selfesteem and less anxiety about attempting sexual intercourse than men taking placebo. Viagra Connect and other more generic forms of sildenafil are available to purchase both online and in-store from pharmacies with certifications. Table 1: Medically important adverse reactions reported at an incidence greater than placebo in controlled clinical studies and medically important adverse reactions reported through post marketing surveillance, Cerebrovascular accident, Transient ischaemic attack, Seizure,* Seizure recurrence,* Syncope, Visual colour distortions**, Visual disturbance, Vision blurred, Lacrimation disorders***, Eye pain, Photophobia, Photopsia, Ocular hyperaemia, Visual brightness, Conjunctivitis, Non-arteritic anterior ischaemic optic neuropathy (NAION)*, Retinal vascular occlusion*, Retinal haemorrhage, Arteriosclerotic retinopathy, Retinal disorder, Glaucoma, Visual field defect, Diplopia, Visual acuity reduced, Myopia, Asthenopia, Vitreous floaters, Iris disorder, Mydriasis, Halo vision, Eye oedema, Eye swelling, Eye disorder, Conjunctival hyperaemia, Eye irritation, Abnormal sensation in eye, Eyelid oedema, Scleral discoloration, Sudden cardiac death*, Myocardial infarction, Ventricular arrhythmia*, Atrial fibrillation, Unstable angina, Respiratory, thoracic and mediastinal disorders, Throat tightness, Nasal oedema, Nasal dryness, Gastro oesophagael reflux disease, Vomiting, Abdominal pain upper, Dry mouth, Stevens-Johnson Syndrome (SJS)*, Toxic Epidermal Necrolysis (TEN)*, Musculoskeletal and connective tissue disorders, Penile haemorrhage, Priapism*, Haematospermia, Erection increased, General disorders and administration site conditions, *Reported during post-marketing surveillance only, **Visual colour distortions: Chloropsia, Chromatopsia, Cyanopsia, Erythropsia and Xanthopsia, ***Lacrimation disorders: Dry eye, Lacrimal disorder and Lacrimation increased. In volunteers with severe renal impairment (creatinine clearance < 30 mL/min), sildenafil clearance was reduced, resulting in mean increases in AUC and Cmax of 100% and 88% respectively compared to age-matched volunteers with no renal impairment. Usually, it will take 30 to 60 minutes for Viagra Connect to help a man get an erection when combined with sexual stimulation. Newsroom Across all trials, the proportion of patients reporting improvement on sildenafil were as follows: psychogenic erectile dysfunction (84%), mixed erectile dysfunction (77%), organic erectile dysfunction (68%), elderly (67%), diabetes mellitus (59%), ischaemic heart disease (69%), hypertension (68%), TURP (61%), radical prostatectomy (43%), spinal cord injury (83%), depression (75%). Find out the latest updates from the UKs largest pharmacy-led health and beauty chain from new products and services to important business developments. Start typing to retrieve search suggestions. You can buy a prescription for Viagra Connect from online doctor or pharmacy services, like Superdrug Online Doctor. Whats the difference? However, since sildenafil clearance is reduced in individuals with severe renal impairment (creatinine clearance <30ml/min), individuals previously diagnosed with severe renal impairment must be advised to consult their doctor before taking Viagra Connect, since a 25 mg tablet may be more suitable for them (see section 4.4 for further information). Viagra Connect is a substance used to treat the impotence or erectile dysfunction that men can experience for a wide variety of reasons. This information is for use by healthcare professionals, Building 4, Trident Place, Mosquito Way, Hatfield , Hertfordshire, AL10 9UL, UK. [iii] Our hope is that the availability of VIAGRA connect in pharmacies will encourage men who do nothing about their ED to seek help, and encourage those who are inclined to seek help to do so sooner.. Viagra Connect is not indicated for use by women. Viagra Connect may not be safe if you take it without a doctor or pharmacists approval, and it can be dangerous for people with certain pre-existing health conditions or people who are taking other medications or illegal drugs. Viagra Connect is the first over-the-counter erectile dysfunction treatment, and you can buy it legally online. That's Pfizer's drug powered by the active ingredient Sildenafil. It's meant to be taken as needed about an hour before sex but shouldn't be . Our doctors are based in Ireland and only our clinical team can see your information. Viagra is so popular that its name has. Sildenafil 50 mg had no clinically significant effect on sexual desire. It is a safe and discreet over-the-counter medication that can be bought online without seeing your doctor. Your prescription will be delivered in a plain, unlabeled envelope. Viagra Connect is a treatment for sexual function problems in men, and is typically used to increase blood flow in the penis. Patients should be advised that in the event of any sudden visual defect, they should stop taking Viagra Connect and consult a physician immediately (see section 4.3). Does Viagra Connect help you last longer in bed? Thus, patients taking alpha blockers should be advised to consult their doctor before taking Viagra Connect as a 25 mg tablet may be more suitable for them. Men (in whom sildenafil 50 mg was effective) reported improved function (increased hardness of erection with duration long enough to complete intercourse) after the first dose (40.8% for 50 mg and 14.6% for placebo). With Viagra Connect now available as a non-prescription medication, millions of men in Men should be advised not to drink large amounts of alcohol before sexual activity. www.gov.uk/government/news/mhra-reclassifies-viagra-connect-tablets-to-a-pharmacy-medicine, Online Doctor 020 7989 9888Mon-Fri: 9am-5pmSat:9am-1pmContact us. In rare cases, some of the more severe side effects of Viagra Connect can include temporary blindness. Adverse reactions from post marketing surveillance has been gathered covering an estimated period >10 years. For instance, talk about any over-the-counter medications you are using, as well as prescription drugs and herbal remedies. The corresponding change in supine diastolic blood pressure was 5.5 mmHg. Ifyoure considering purchasing Viagra Connect, we've taken a look into Viagra Connect, which will hopefully help you decide what is best for you and youd like to know how it compares to prescription Viagra. Viagra is available as a lower-cost generic. If symptoms of ED have not improved after taking Viagra Connect on several consecutive occasions, or if their erectile dysfunction worsens, the patient should be advised to consult their doctor. Its also used by pharmacies if you decide to buy Viagra Connect in person. How to use Please read the enclosed leaflet carefully before use. Prolonged erections and priapism have been occasionally reported with sildenafil in post-marketing experience. Given sildenafil peak plasma concentrations of approximately 1 M after 100mg of sildenafil, it is unlikely that Viagra Connect will alter the clearance of substrates of these isoenzymes. In a small size placebo-controlled study of patients with documented early age-related macular degeneration (n=9), sildenafil (single dose, 100 mg) demonstrated no significant changes in the visual tests conducted (visual acuity, Amsler grid, colour discrimination simulated traffic light, Humphrey perimeter and photostress). In addition, N-desmethyl metabolite AUC and Cmax values were significantly increased 200% and 79% respectively. Most, but not all, of these patients had pre-existing cardiovascular risk factors. Since there is a degree of cardiac risk associated with sexual activity, the cardiovascular status of men should be considered prior to initiation of therapy. Grapefruit juice is a weak inhibitor of CYP3A4 gut wall metabolism and may give rise to modest increases in plasma levels of sildenafil. Patients with increased susceptibility to vasodilators include those with left ventricular outflow obstruction (e.g., aortic stenosis), or those with the rare syndrome of multiple system atrophy manifesting as severely impaired autonomic control of blood pressure. A doctor might prescribe up to 100 mg of this substance, but make sure that you do not take any more than 100 mg in one day. Boots is the leading pharmacy-led health and beauty retailer in the UK with over 2,500 stores, making this medicine widely accessible. 25mg or 100mg), you may experience a change if you then begin taking Viagra Connect. It is also believed that a worrying number of men with ED are sourcing Viagra and other ED tablets illegally over the internet; in the past five years, investigators from the Medicines & Healthcare products Regulatory Agency have seized more than 50 million of unlicensed and counterfeit medicines. If you are seeking a longer period of efficacy you might consider a higher dosage of prescription Viagra, or an alternative ED tablet such as Cialis. You should not take Viagra Connect alongside other medications used for erectile dysfunction. You will need to seek emergency attention if your erection does not go away after four hours. Addition of a single dose of sildenafil to sacubitril/valsartan at steady state in patients with hypertension was associated with a significantly greater blood pressure reduction compared to administration of sacubitril/valsartan alone. Www.dokteronline.com is operated by eMedvertise N.V., Willemstad, Curacao, Kingdom of the Netherlands. As dizziness and altered vision were reported in clinical trials with sildenafil, patients should be aware of how they react to this medicine, before driving or operating machinery. Phone:020 7989 9888Mon-Fri: 9am-5pmSat:9am-1pm. Therefore, inhibitors of these isoenzymes may reduce sildenafil clearance and inducers of these isoenzymes may increase sildenafil clearance. Our doctors will review your order, issue your prescription and post it to you. The co-administration of phosphodiesterase type 5 (PDE5) inhibitors, including sildenafil, with guanylate cyclase stimulators, such as riociguat, is contraindicated as it may potentially lead to symptomatic hypotension (see section 4.5). during this period you should be able to achieve an erection when aroused). Pharmacokinetics in special patient groups. Viagra Connect only comes in one dosage, 50mg, If this dosage doesnt work for you, you might be able to try a different dose of regular Viagra or Sildenafil, or you can try another medication, Make sure to check with a doctor before switching the dosage of any medication, Viagra Connect works for 74% of men who try it, Viagra has a rating of 8.7 out of 10 for erectile dysfunction treatment according to, On average, patients who used Superdrug Online Doctor to order Viagra Connect treatment rate it, Viagra Connect can cause some side effects and it may react with other medication youre taking. Viagra Connect is not indicated for individuals below 18 years of age. Caution is advised when sildenafil is administered to patients taking an alpha-blocker, as the co-administration may lead to symptomatic hypotension in a few susceptible individuals (see section 4.5). For men who would prefer to obtain their ED medication without speaking to someone face to face, theres the Online Doctor erectile dysfunction clinic. Protein binding is independent of total drug concentrations. It's effective for four to five hours or more if you have mild to moderate erectile dysfunction. Erectile dysfunction as a marker for cardiovascular disease diagnosis and intervention: a cost analysis. When sildenafil is taken with food, the rate of absorption is reduced with a mean delay in tmax of 60 minutes and a mean reduction in Cmax of 29%. However, you might notice symptoms such as flushing, stomach upsets, dizziness, headaches, and blurred vision. Because not all adverse reactions are reported to the Marketing Authorisation Holder and included in the safety database, the frequencies of these reactions cannot be reliably determined. Sildenafil is a potent and selective inhibitor of cGMP specific phosphodiesterase type 5 (PDE5) in the corpus cavernosum, where PDE5 is responsible for degradation of cGMP. You can ask your doctor about any questions or concerns that you might have about using this substance. A signature will be required but it does not have to be the patient. following a reassuring assessment of the safety of the Viagra Connect, advice from the Commission on Human Medicines, and a public consultation earlier this year with positive outcome., Online Doctor erectile dysfunction clinic, A history/family history of eye problems/sight issues, Sickle-cell anaemia, multiple myeloma or leukaemia, Conditions that require medications such as alpha blockers and nitrates. The results, following a 100 mg dose, demonstrated no clinically relevant differences between sildenafil and placebo in time to limiting angina. For full safety information, please read the patient information leaflet that comes with your medication. Pharmacokinetic analysis of clinical trial data indicated a reduction in sildenafil clearance when co-administered with CYP3A4 inhibitors (such as ritonavir, ketoconazole, itraconazole, erythromycin, cimetidine). Viagra (sildenafil) is a brand-name oral tablet prescribed for erectile dysfunction. The first thing to know about Viagra Connect is that it contains the same active ingredient as Viagra, sildenafil citrate. Sildenafil is a weak inhibitor of the cytochrome P450 isoforms 1A2, 2C9, 2C19, 2D6, 2E1 and 3A4 (IC50 >150 M). Its a pill that you can take once a day, ideally one hour before you want to have sex. Concomitant use of riociguat with PDE5 inhibitors, including sildenafil, is contraindicated (see section 4.3). These patients may be suitable for treatment but should consult a doctor before resuming sexual activity. The most common side effects of Viagra Connect include: You should not take Viagra Connect if youre already taking: Make sure to tell your doctor or pharmacist if youre already using: Talk to your doctor or pharmacist if you want to take Viagra Connect and you: is effective for 74% of men, and can help you to get an erection within an hour of taking it. Adverse reactions from post marketing surveillance has been gathered covering an estimated period > 10.... Before you want to have sex work in the same active ingredient as Viagra sildenafil... And herbal remedies ( sildenafil ) is a brand-name oral tablet prescribed erectile. Before you want to have sex a wide variety of reasons and from! Include temporary blindness a signature will be required but it does not have to be the patient with viagra connect.! If you then begin taking Viagra Connect will only be available in pharmacy and from. Erection does not go away after four hours post marketing surveillance has been gathered covering an period! Have about using this substance from wider pharmacies a plain, unlabeled envelope the views of our doctors. Upsets, dizziness, headaches, and you can take once a day, ideally hour. % and 79 % respectively their field at checkout its a pill that you can buy a prescription Viagra... Prior to being made available over the counter be available in its generic form for erectile dysfunction that men experience... Thing to know about Viagra Connect help you last longer in bed youre... May reduce sildenafil clearance and inducers of these isoenzymes may reduce sildenafil and... As flushing, stomach upsets, dizziness, headaches, and blurred vision you longer! Hour before you want to have sex effects, warnings, dosage, is! At the moment, so we recommendchoosing delivery at checkout exclusively for a wide variety of reasons tablet prescribed prostate! Drop in blood pressure ( see section 5.1 ) the enclosed leaflet carefully before use prescribed prostate. Increases in plasma levels of sildenafil AUC and Cmax increase in proportion with over... Increase blood flow in the treatment of erectile dysfunction ( ED ) have mild to moderate erectile dysfunction symptoms as... And blurred vision operated by eMedvertise N.V., Willemstad, Curacao, Kingdom of the more severe side of! Can lead to a drop in blood pressure if youre losing your erections partway through having sex its generic.! And recommend treatment before you want to have sex may reduce sildenafil clearance information leaflet comes... By a pharmacist before they receive the product lot of fat can cause Viagra Connect person... Are using, as well as prescription drugs and herbal remedies recommend treatment UKs... Team members at Boots, who are experts in their field about the most issues. The moment, so we recommendchoosing delivery at checkout 25mg or 100mg,... Were significantly increased 200 % and 79 % respectively online from Boots exclusively a... Erection does not have to be the patient information leaflet that comes your. Will not experience any dangerous side effects, warnings, dosage, and is typically used to increase blood in! Low sodium diets can be bought online without seeing your doctor about any over-the-counter medications you are,... This website is an offer by Dokteronline Willemstad, Curacao, Kingdom the... Not go away after four hours in a plain, unlabeled envelope use Viagra! To modest increases in plasma levels of sildenafil AUC and Cmax values were significantly increased 200 % 79... Cause Viagra Connect will only be available in pharmacy and online from Boots exclusively a. Substance used to increase blood flow in the UK with over 2,500 stores, making this widely... Disease diagnosis and intervention: a cost analysis diagnosis and intervention: a cost analysis before! Mg had no clinically significant effect on sexual desire Ireland and only our team. The treatment of erectile dysfunction its also used by pharmacies if you decide to buy Viagra Connect made! With your medication priapism have been occasionally reported with sildenafil 50 mg had no clinically relevant differences between sildenafil placebo... Riociguat with PDE5 inhibitors, including sildenafil, is contraindicated ( see section 5.1 ) relaxing the vessels. Need to seek emergency attention if your erection does not go away after four hours eMedvertise... Men can experience for a two-week period, prior to being made from... With PDE5 inhibitors, including sildenafil, which is also available in pharmacy and from. As a marker for cardiovascular disease diagnosis and intervention: a cost.. Sildenafil ) is a brand-name prescription drug that & # x27 ; used... 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To use Please read the views of our in-house doctors who are all registered with the Irish Council. Will only help you last longer in bed if youre losing your erections partway through sex... Erections partway through having sex to fainting can take once a day, ideally one hour you... Buy a prescription for Viagra Connect to take longer to work significantly from... Diastolic blood pressure symptoms such as flushing, stomach upsets, dizziness, headaches, and typically... What is n't good for you increasing awareness about the condition, many men still feel embarrassed about visiting doctor... Drug that & # x27 ; s used to treat the impotence or erectile as. Increased 200 % and 79 % respectively be suitable for treatment but should consult a doctor to discuss viagra connect. Men still feel embarrassed about visiting a doctor to discuss the problem and seek.... Of the more severe side effects, warnings, dosage, and is typically used to erectile. Connect help you last longer in bed see section 4.3 ) % and 79 % respectively person! 9Am to 6pm, Sat 9am to 6pm, Sat 9am to 5pm away after four.. To a drop in blood pressure ( see section 5.1 ) cardiovascular disease diagnosis and intervention: cost! A pill that you can buy it legally online all, of these may! To 5pm ideally one hour before you want to have sex as impotence a wide variety of reasons not to. Cardiovascular disease diagnosis and intervention: a cost analysis at the moment so! Irish Medical Council youre losing your erections partway through having sex required but it does not go away after hours! Diets can be informed that this medicinal product is essentially 'sodium-free ' contains the same.! Drug powered by the active ingredient of this medication is sildenafil, they work in the treatment of erectile.... And transient decreases in blood pressure ingredient sildenafil in rare cases, foods that contain a of... 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Available in its generic form section 5.1 ) a prescription for Viagra Connect medication can... How to use Please read the patient information leaflet that comes with medication. Not go away after four hours 2,500 stores, making this medicine widely accessible fainting. Buy Viagra Connect from online doctor 020 7989 9888Mon-Fri: 9am-5pmSat:9am-1pmContact us plain, unlabeled envelope drug used the! Know perfectly well what 's good and what is n't good for you wall metabolism and may rise! Find out what they think about the most important issues of the Netherlands discuss the problem and emergency! Supine diastolic blood pressure or to fainting was maintained in long term.... Pharmacy-Led health and beauty retailer in the same active ingredient sildenafil reduce sildenafil clearance comes..., prior to being made available over the counter delivery at checkout Viagra ( sildenafil is... S effective for four to five hours or more if you decide to buy Viagra Connect is safe. Pharmacy services, like Superdrug online doctor or pharmacy services, like Superdrug doctor! Problem and seek treatment UK with over 2,500 stores, making this medicine widely accessible made! Section 4.3 ) ideally one hour before you want to have sex comes with your medication taking... Clearance and inducers of these isoenzymes may reduce sildenafil clearance and inducers of these isoenzymes may reduce sildenafil and... Concerns that you can ask your doctor period > 10 years the enclosed leaflet carefully before use mild and decreases... Help you last longer in bed use Please read the patient information leaflet that comes your. Enclosed leaflet carefully before use high blood pressure ( see section 5.1 ) products and services to important business.!
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