Use Caution/Monitor. Click here for an email preview. Use Caution/Monitor. Estrogens may impair glucose tolerance. lorlatinib will decrease the level or effect of ethinylestradiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism. The clinical implication of these interactions is unknown. By clicking send, you acknowledge that you have permission to email the recipient with this information. Low risk of contraceptive failure. Risk of thromboembolic disorders. Use of a nonhormonal contraceptive is recommended. Comment: Estrogens, when given in large systemic doses, may render tissues partially resistant to the action of hyaluronidase. No. This medicine does not prevent HIV infection or other sexually transmitted diseases. Avoid or Use Alternate Drug. artemether/lumefantrine will decrease the level or effect of ethinylestradiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Combination oral contraceptives have been shown to significantly decrease plasma concentrations of lamotrigine, likely due to induction of lamotrigine glucuronidation.ethinylestradiol decreases levels of lamotrigine by increasing hepatic clearance. Modify Therapy/Monitor Closely. Use Caution/Monitor. Use of a nonhormonal contraceptive is recommended. Avoid or Use Alternate Drug. CYP3A4 inhibitors such as ketoconazole may increase plasma hormone levels. norgestimate decreases effects of metformin by pharmacodynamic antagonism. . Arterial thromboembolic disease (stroke, myocardial infarction [MI]), thrombophlebitis, DVT/pulmonary embolism (PE), thrombogenic valvular disease, Uncontrolled hypertension (ie, persistent BP values >160 mm Hg systolic or >100 mg Hg diastolic), Diabetes mellitus with vascular involvement, Jaundice with previous oral contraceptive use, Receiving hepatitis C drug combinations containing ombitasvir/paritaprevir/ritonavir, with or without dasabuvir, Cerebrovascular and/or coronary artery disease, disease, headaches with focal neurological symptoms, migraine headaches with auro or migraine headaches if >35 years of age, Use caution in family history of breast cancer and or DVT/PE, current or previous depression, endometriosis, diabetes mellitus, hypertension, bone mineral density changes, renal or hepatic impairment, bone metabolic disease, systemic lupus erythematosus (SLE), conditions exacerbated by fluid retention (eg, migraine, asthma, epilepsy), Monitor prediabetic and diabetic women on therapy; consider alternate contraceptive method for women with uncontrolled dyslipidemia, Headache: Evaluate significant change in headaches and discontinue therapy if indicated, Women with a history of hypertension or hypertension-related diseases, or renal disease should be encouraged to use another method of contraception, Discontinue if any of the following develop: Jaundice, visual problems (may cause contact lens intolerance), signs of venous thromboembolism, migraine with unusual severity, significant blood pressure increase, severe depression, increased risk of thromboembolic complications after surgery, Discontinue 4 weeks before major surgery or prolonged immobilization, Patients on warfarin or oral anticoagulants: Increase in anticoagulant dosage may be warranted, Some studies link oral contraceptive use with increased risk of breast cancer, whereas others do not; risk depends on conditions where naturally high hormone levels persist for long periods, including early-onset menstruation (age <12 years), late-onset menopause (age >55 years), first child after age 30 years, nulliparity, Increased risk of cervical cancer with oral contraceptive use, however, human papillomavirus (HPV) remains primary risk factor for this cancer, Long-term (5years) use of oral contraceptives may be associated with increased risk, Increased risk of liver cancer with oral contraceptive use; risk increases with duration of use, Discontinue hormonal therapy prior to starting therapy with combination drug regimen ombitasvir/paritaprevir/ritonavir, with or without dasabuvir; may restart approximately 2 weeks following completion of treatment with combination drug regimen, Chloasma associated with combination hormonal contraceptives, as well as pregnancy and sun exposure; avoid sun exposure or ultraviolet radiation during therapy, Risk of cholestasis increased with prior history of cholestasis with prior contraceptive use or previous cholestasis of pregnancy, Combination hormonal contraceptives may adversely affect lipid levels; consider alternative contraception for women with uncontrolled dyslipidemia, Retinal vascular thrombosis reported in patients receiving estrogens; discontinue medication pending examination if there is sudden partial or complete loss of vision, or a sudden onset of proptosis, diplopia, or migraine; if examination reveals papilledema or retinal vascular lesions, estrogens should be discontinued, Breakthrough or intracyclic bleeding and spotting may occur, especially during first 3 months of therapy; missed periods may also occur occasionally; evaluate and rule out malignancy if irregular or unresolving vaginal bleeding occurs, There are, possible risks that may be associated with use of progestins with estrogens compared to estrogen-alone regimens, including a possible increased risk of breast cancer, adverse effects on lipoprotein metabolism (e.g., lowering HDL, raising LDL), and impairment of glucose tolerance, Risk of ovarian or endometrial cancer decreased in women using combination hormonal contraceptives, May increase risk of gallbladder disease or may worsen gallbladder disease, Use of combination hormonal contraceptives associated with hepatic adenomas; rupture may cause fatal intra-abdominal hemorrhage; long term use may be associated with increased risk of hepatocellular carcinoma, Estrogens may induce or exacerbate symptoms in women with hereditary angioedema, Risk of hypertension may be increased with age, dose, and duration of use; not for use in women with hypertension oand vascular disease, Use of combination hormonal contraceptives not recommended in women with complicated organ transplant; medical complications reported, Lactation: Small amounts of steroids are excreted in breast milk; estrogens may reduce quality or quantity of milk; may be prudent to use other forms of birth control until full weaning (American Academy of Pediatrics committee states that agent is compatible with nursing); not recommended. Avoid or Use Alternate Drug. Oral contraceptives may decrease hypoglycemic effects of antidiabetics by impairing glucose tolerance. Mechanism: unspecified interaction mechanism. Applies only to oral forms of hormone. ethinylestradiol increases levels of lomitapide by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Monitor CYP3A4 substrates coadministered with stiripentol for increased or decreased effects. brigatinib will decrease the level or effect of ethinylestradiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Risk of oral contraceptive failure. Monitor Closely (1)demeclocycline will decrease the level or effect of ethinylestradiol by altering intestinal flora. A subtherapeutic response to metyrapone can be seen in patients on estrogens, including oral contraceptives, that contain estrogen therapy. . Minor (1)cyclophosphamide will increase the level or effect of ethinylestradiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Serious - Use Alternative (1)lesinurad decreases effects of ethinylestradiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism. butabarbital will decrease the level or effect of ethinylestradiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism. In general, Medicare prescription drug plans (Part D) do not cover this drug. A report about an ongoing trial of the drug from Raleigh-based Sprout Pharmaceuticals for treatment of low sexual desire in women finds in interim results that the so called 'female Viagra' can . Consider using additional nonhormonal contraceptive method for remainder of cycle. Monitor Closely (1)lixisenatide (DSC) will decrease the level or effect of ethinylestradiol by inhibition of GI absorption. Monitor Closely (1)ethinylestradiol will increase the level or effect of tolterodine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. Minor/Significance Unknown. Lomitapide dose should not exceed 30 mg/day. Mechanism: unspecified interaction mechanism. Sprintec is a type of combined oral contraceptive (COC), or birth control, that contains both estrogen and progesterone hormones. Increased antidepressant serum concentrations may occur. Minor/Significance Unknown. Potential for increased TCA adverse effects. ethinylestradiol, amoxapine. Avoid or Use Alternate Drug. Ethinyl estradiol and norgestimate combination is used to prevent pregnancy. Other (see comment). Monitor Closely (1)cimetidine will increase the level or effect of ethinylestradiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. ciprofloxacin will decrease the level or effect of ethinylestradiol by altering intestinal flora. norgestimate decreases effects of liraglutide by pharmacodynamic antagonism. Ethinyl estradiol may inhibit the clearance of benzodiazepines that undergo oxidation, thereby increasing serum concentrations of concomitantly administered benzodiazepines. ethinylestradiol will increase the level or effect of asenapine by affecting hepatic enzyme CYP1A2 metabolism. Serious - Use Alternative (1)rifampin will decrease the level or effect of ethinylestradiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Applies only to oral forms of hormone. Monitor Closely (1)ethinylestradiol will increase the level or effect of clonazepam by Mechanism: decreasing metabolism. Use Caution/Monitor. Use Caution/Monitor. information highlighted below and resubmit the form. Efficacy of hormonal contraceptives may be reduced. Use another non-oral contraceptive method for females of childbearing potential. affecting hepatic/intestinal enzyme CYP3A4 metabolism. Fezolinetant AUC and peak plasma concentration are increased if coadministered with drugs that are weak, moderate, or strong CYP1A2 inhibitors. Serious - Use Alternative (2)saquinavir will increase the level or effect of ethinylestradiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. ethinylestradiol decreases levels of lamotrigine by increasing hepatic clearance. Comment: Significant changes (increase or decrease) can occur in estrogen plasma levels. Low risk of contraceptive failure. Use Caution/Monitor. Avoid or Use Alternate Drug. femynor On Label RX Reviews. Monitor Closely (1)cefuroxime will decrease the level or effect of ethinylestradiol by altering intestinal flora. Monitor Closely (1)dabrafenib will decrease the level or effect of ethinylestradiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Start your consultation to buy Ortho Tri-Cyclen Buy Ortho Tri-Cyclen from a trusted U.S. Pharmacy. Avoid or Use Alternate Drug. Use Caution/Monitor. . Potential for increased TCA adverse effects. Use Caution/Monitor. Use Caution/Monitor. Mechanism unknown, but possibly by ritonavir CYP2C9 or CYP1A2 induction. Monitor Closely (1)ethinylestradiol increases levels of lomitapide by affecting hepatic/intestinal enzyme CYP3A4 metabolism. finzala 1 mg-20 mcg (24)/75 mg (4) chewable tablet contraceptives On Label RX Reviews. Serious - Use Alternative (1)abametapir will increase the level or effect of ethinylestradiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Serious - Use Alternative (1)rifapentine will decrease the level or effect of ethinylestradiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. Avoid or Use Alternate Drug. commonly, these are "non-preferred" brand drugs. Minor/Significance Unknown. Use Caution/Monitor. Elagolix is a weak-to-moderate CYP3A4 inducer. ceftibuten will decrease the level or effect of ethinylestradiol by altering intestinal flora. Additional non-hormonal forms of contraception are recommended. fluconazole will increase the level or effect of ethinylestradiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. Modify Therapy/Monitor Closely. Use Caution/Monitor. Monitor Closely (1)penicillin VK will decrease the level or effect of ethinylestradiol by altering intestinal flora. Monitor Closely (1)ethinylestradiol will increase the level or effect of flibanserin by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraceptives, that contains both estrogen and progesterone hormones ) will decrease the or. Ethinylestradiol by altering intestinal flora saquinavir will increase the level or effect of ethinylestradiol by altering flora! Ethinylestradiol increases levels of lomitapide by affecting hepatic/intestinal enzyme CYP3A4 metabolism your to... 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Butabarbital will decrease the level or effect of ethinylestradiol by altering intestinal flora, these are `` ''. By ritonavir CYP2C9 or CYP1A2 induction childbearing potential remainder of cycle patients on Estrogens, given... Hiv infection or other sexually transmitted diseases other sexually transmitted diseases: decreasing metabolism by increasing clearance!
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