Minor/Significance Unknown. There havent been enough studies done in humans to be certain how the drug might affect the fetus. Either increases toxicity of the other by pharmacodynamic synergism. For women who are breastfeeding: Theophylline may pass into breast milk and may cause side effects in a child who is breastfed. Upon initiation or discontinuation of dupilumab in patients who are receiving concomitant CYP450 substrates, particularly those with a narrow therapeutic index, consider monitoring for therapeutic effect. Comment: Formation of CYP450 enzymes can be altered by increased levels of certain cytokines during chronic inflammation; thus, secukinumab could normalize the formation of CYP450 enzymes. Use Caution/Monitor. Smoking increases risk of interaction. Erections happen when a protein called cyclic guanosine monophosphate (cGMP). All rights reserved. Modify Therapy/Monitor Closely. Modify Therapy/Monitor Closely. Monitor Closely (1)levonorgestrel oral/ethinylestradiol/ferrous bisglycinate will increase the level or effect of theophylline by decreasing metabolism. Modify Therapy/Monitor Closely. Use Caution/Monitor. Avoid or Use Alternate Drug. Smoking increases risk of interaction. Avoid or Use Alternate Drug. Consult your pharmacist or local waste disposal company. Its available as an oral solution, an extended-release tablet, and an extended-release capsule. Extended Release Tablets (400 or 600 mg): This effect was not observed with istradefylline 20 mg/day. allopurinol increases levels of theophylline by decreasing metabolism. Use Caution/Monitor. Monitor Closely (1)cigarette smoking will decrease the level or effect of theophylline by affecting hepatic enzyme CYP1A2 metabolism. They will show you how to do this. A class of drugs is a group of medications that work in a similar way. Monitor Closely (1)carbamazepine will decrease the level or effect of theophylline by affecting hepatic enzyme CYP1A2 metabolism. Other (see comment). Use Caution/Monitor. Blood tests may be needed to check for unwanted effects. Use Caution/Monitor. labetalol, theophylline. Extended release tablets may pass an intact tablet matrix in the stool or colostomy bag which has little or no theophylline remaining. Use Caution/Monitor. Elagolix is a weak-to-moderate CYP3A4 inducer. It works by reducing . Smoking increases risk of interaction. commonly, these are "preferred" (on formulary) brand drugs. Minor (1)levothyroxine decreases levels of theophylline by increasing elimination. Combined oral contraceptives containing EE may inhibit the metabolism and increase plasma concentrations of cyclosporine. After 3 more days, if tolerated: 600 mg per day given as evenly divided doses every 6 to 8 hours Monitor for increased concentrations or toxicities of sensitive CYP substrates. After 3 more days, your dose may be adjusted as needed based on the level of theophylline in your blood. affecting hepatic enzyme CYP1A2 metabolism. Talk to your doctor if you breastfeed your child. After 3 days, your doctor may increase your dose to 16 mg/kg daily up to a maximum of 400 mg per day if you dont have any side effects. 2010theo-24-theochron-theophylline-343447Drugs, 20022129484-overviewDiseases & Conditions, encoded search term (theophylline (Theo 24%2C Theocron)) and theophylline (Theo 24, Theocron), In-Hospital Antibiotic Use for Severe Chronic Obstructive Pulmonary Disease Exacerbations, Is Immunotherapy Safe for Treatment of Severe Asthma. Monitor Closely (1)marijuana will increase the level or effect of theophylline by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Talk to your pharmacist for more details.Before using this medication, tell your doctor or pharmacist your medical history, especially of: stomach/intestinal ulcer, seizures, thyroid disease, heart problems (such as heart failure, irregular heartbeat), liver disease, high blood pressure.If you get sick or have a fever while taking this medication, tell your doctor right away. Contraindicated. For non-prescription products, read the label or package ingredients carefully. They relieve cough, wheezing, shortness of breath, and troubled breathing by increasing the flow of air through the bronchial tubes. Humid air can be hard to breathe and it can also trap allergens and pollutants. Use serum theophylline concentrations to determine if a dose is appropriate. When taken with theophylline, you may need a larger dose of lithium for it to work. Consult your doctor for more details. Minor (1)disulfiram increases levels of theophylline by decreasing metabolism. Always speak with your doctor or pharmacist about dosages that are right for you. These side effects may go away during treatment as your body adjusts to the medicine. Comment: Prolonged use of proton pump inhibitors can cause hypochlorhydria, which in turn causes peristalsis in small intestine to increase and peristalsis in the proximal colon to decrease; monitor for toxicity. Monitor Closely (1)siltuximab, theophylline. fedratinib will increase the level or effect of theophylline by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Monitor Closely. Minor/Significance Unknown. Napumpujte ho antioxidantmi a vitamnmi! Avoid the concomitant use of theophylline with deferasirox. Maximum dose: 400 mg per day For 2 weeks after abametapir application, avoid taking drugs that are CYP3A4 substrates. Monitor Closely (1)obeticholic acid will increase the level or effect of theophylline by affecting hepatic enzyme CYP1A2 metabolism. Npoje s vysokm obsahom antioxidantov, ako s vitamny C a E, preukzatene zlepuj erektiln funkciu tm, e brnia pokodeniu buniek, produkujcich oxid dusnat," hovor Pearlmanov. Individual plans may vary ixekizumab, theophylline. clarithromycin increases levels of theophylline by decreasing metabolism. Coadministration increases risk of CNS depression, which can lead to additive impairment of psychomotor performance and cause daytime impairment. After you or your child begin taking theophylline, it is very important that your doctor check the level of the medicine in the blood at regular intervals to decide if the dose needs to be changed. ketoconazole will increase the level or effect of theophylline by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Tecovirimat is a weak CYP3A4 inducer. If concomitant use cannot be avoided, monitor theophylline levels and adjust dosage as needed.ciprofloxacin will increase the level or effect of theophylline by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Tell your doctor if you smoke or if you have recently stopped smoking.Caffeine and alcohol can increase the side effects of this medication. Use Caution/Monitor. Avoid the concomitant use of theophylline with deferasirox. Use Caution/Monitor. Other (see comment). If unavoidable, reduce CYP3A substrate dose according to product labeling. It does not work right away and should not be used to relieve sudden breathing problems. Comment: Formation of CYP450 enzymes can be altered by increased levels of certain cytokines during chronic inflammation; thus, secukinumab could normalize the formation of CYP450 enzymes. Avoid concurrent use of CYP3A substrates known to have narrow therapeutic indices or substrates primarily metabolized by CYP3A during treatment with ceritinib; if use of these medications is unavoidable, consider dose. Use Caution/Monitor. Use Caution/Monitor. non selective) antagonize theophylline effects, while at the same time increasing theophylline levels and toxicity (mechanism: decreased theophylline metabolism). Comment: Teduglutide may increase absorption of concomitant PO medications; caution with with drugs requiring titration or those with a narrow therapeutic index; dose adjustment may be necessary. Use Caution/Monitor. butabarbital will decrease the level or effect of theophylline by affecting hepatic enzyme CYP1A2 metabolism. Monitor Closely (1)guselkumab, theophylline. Use Caution/Monitor.verapamil will increase the level or effect of theophylline by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. Use Caution/Monitor. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco. celiprolol, theophylline. Fezolinetant AUC and peak plasma concentration are increased if coadministered with drugs that are weak, moderate, or strong CYP1A2 inhibitors. However, the total dose is usually not more than 600 mg per day. elvitegravir/cobicistat/emtricitabine/tenofovir DF increases levels of theophylline by affecting hepatic/intestinal enzyme CYP3A4 metabolism. teclistamab will increase the level or effect of theophylline by altering metabolism. Initial dose: 300 mg per day given as evenly divided doses every 6 to 8 hours After 3 days, if starting dose was tolerated: 400 mg per day given as evenly divided doses every 6 to 8 hours After 3 more days, if tolerated: 600 mg per day given as evenly divided doses every 6 to 8 hours (2016, December), Theophylline may interact with other medications, Important considerations for taking theophylline, dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=1f2a4716-34fe-4a2c-8bbf-5ed16772a967, dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=77e849b8-900b-4f0d-ac5c-1391abcd5721, Exploring the Connections Between RSV and Asthma, How Effective Is Acupuncture for Treating Asthma? Coadministration with drugs that lower seizure threshold may increase this risk. Monitor Closely (1)teclistamab will increase the level or effect of theophylline by altering metabolism. Monitor Closely (1)omaveloxolone will decrease the level or effect of theophylline by affecting hepatic/intestinal enzyme CYP3A4 metabolism. pindolol, theophylline. Use Caution/Monitor. Some of the adverse effects associated with theophylline appear to be mediated by inhibition of PDE III (e.g., hypotension, tachycardia, headache, and emesis) and adenosine receptor antagonism (e.g., alterations in cerebral blood flow). And. Comment: Beta blockers (esp. Monitor Closely (2)secobarbital will decrease the level or effect of theophylline by affecting hepatic enzyme CYP1A2 metabolism. smoking will decrease the level or effect of theophylline by affecting hepatic enzyme CYP1A2 metabolism. Avoid or Use Alternate Drug. Smoking increases risk of interaction. Crofelemer has the potential to inhibit CYP3A4 at concentrations expected in the gut; unlikely to inhibit systemically because minimally absorbed. Comment: Beta blockers (esp. Do not double doses. Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up-to-date. theophylline decreases effects of regadenoson by pharmacodynamic antagonism. restrictions. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.This is not a complete list of possible side effects. Other (see comment). Other (see comment). CYP1A2 substrates may require dosage adjustment.stiripentol, theophylline. Avoid or Use Alternate Drug. mexiletine will increase the level or effect of theophylline by affecting hepatic enzyme CYP1A2 metabolism. Use Caution/Monitor. Use Caution/Monitor. Children 1 year of age and older weighing 20 kg or less10 mg 3 times a day. Queens of the Stone Age will bring Phantogram, Viagra Boys, the Armed, and Savages' Jehnny Beth on their fall North American tour. Use Caution/Monitor. Monitor Closely (1)darunavir will increase the level or effect of theophylline by affecting hepatic/intestinal enzyme CYP3A4 metabolism. The dose will be adjusted based on the amount of theophylline in the blood. Children younger than 6 years of ageUse and dose must be determined by your doctor. Do not take more of it and do not take it more often than your doctor ordered. Use Caution/Monitor. Medically reviewed by Drugs.com. Smoking increases risk of interaction. Minor (1)theophylline increases levels of cilostazol by decreasing metabolism. Avoid or Use Alternate Drug. Use Caution/Monitor. Theophylline oral tablet is only available as a generic drug. non selective) antagonize theophylline effects, while at the same time increasing theophylline levels and toxicity (mechanism: decreased theophylline metabolism). Monitor Closely (1)grapefruit will increase the level or effect of theophylline by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Monitor Closely (1)methotrexate increases levels of theophylline by unknown mechanism. Smoking increases risk of interaction. Use Caution/Monitor. lenacapavir will increase the level or effect of theophylline by affecting hepatic/intestinal enzyme CYP3A4 metabolism. This drug is given in divided doses every 46 hours. Either increases effects of the other by sedation. Monitor Closely (1)ethinylestradiol will increase the level or effect of theophylline by affecting hepatic enzyme CYP1A2 metabolism. Use Caution/Monitor. Upon initiation or discontinuation of secukinumab in patients who are receiving concomitant CYP450 substrates, particularly those with a narrow therapeutic index, consider monitoring for therapeutic effect. Avoid or Use Alternate Drug. Saliva theophylline concentrations are not reliable for dose adjustments without special techniques. crizotinib increases levels of theophylline by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Serious and fatal reactions have included cardiac arrest, seizure, status epilepticus, and respiratory failure. Monitor Closely (1)theophylline and olodaterol inhaled both decrease serum potassium. dasatinib will increase the level or effect of theophylline by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Serious side effects and their symptoms can include the following: Disclaimer: Our goal is to provide you with the most relevant and current information. For the second half of the tour, QOTSA will join forces with likeminded spirits Viagra Boys and with former Savages leader Jehnny Beth. Comment: Formation of CYP450 enzymes can be altered by increased levels of certain cytokines during chronic inflammation; thus, normalizing the formation of CYP450 enzymes. Use Caution/Monitor. Either increases effects of the other by additive vasodilation. All material on this website is protected by copyright, Copyright 1994-2023 by WebMD LLC. The . These CBD candies offer a simple and flexible . Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. Elevated IL-6 concentration may down-regulate CYP activity, such as in patients with RA, and, hence, increase drug levels compared with subjects without RA. Upon initiation or discontinuation of ustekinumab in patients who are receiving concomitant CYP450 substrates, particularly those with a narrow therapeutic index, consider monitoring for therapeutic effect. You may need to decide whether to stop breastfeeding or stop taking this medication. To find out how this drug might interact with something else youre taking, talk to your doctor or pharmacist. erythromycin lactobionate will increase the level or effect of theophylline by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Always carry your medication with you. Minor/Significance Unknown. in vivo . theophylline concentrations 10 mcg/mL or higher), obtain a second measurement after one expected half-life (the manufacturer product information should be consulted) and compare to determine an appropriate infusion rate. Minor/Significance Unknown. nefazodone will increase the level or effect of theophylline by affecting hepatic/intestinal enzyme CYP3A4 metabolism. This may increase the amount of this drug in your body and cause more side effects. Otherwise, call a poison control center right away. thyroid desiccated decreases levels of theophylline by increasing elimination. lapatinib will increase the level or effect of theophylline by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Monitor Closely (1)metoprolol, theophylline. Stiripentol is a CYP1A2 inhibitor and inducer. Use Caution/Monitor. Combination may increase risk of hypokalemia. Monitor CYP3A4 substrates coadministered with stiripentol for increased or decreased effects. Use Caution/Monitor. Minor (1)cyclophosphamide will increase the level or effect of theophylline by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Un programa que dej de tener gracia cuando se. It works by relaxing the muscles around the airways so that they open up and you can breathe more easily. affecting hepatic/intestinal enzyme CYP3A4 metabolism. Comment: Amifampridine can cause seizures. Blockade of IL-6 signaling by IL-6 antagonists (eg, sarilumab) might reverse the inhibitory effect of IL-6 and restore CYP activity, leading to decreased drug concentrations. Controlled studies in pregnant women show no evidence of fetal risk. Use Caution/Monitor. The theophylline tablet is only available as a generic drug. Use Caution/Monitor. Older adultsThe dose must be determined by your doctor. Monitor theophylline levels. This information does not assure that this product is safe, effective, or appropriate for you. voriconazole will increase the level or effect of theophylline by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Teclistamab causes release of cytokines that may suppress activity of CYP450 enzymes, resulting in increased exposure of CYP substrates. Comment: Avoid use of metoclopramide intranasal or interacting drug, depending on importance of drug to patient. Use Caution/Monitor. Comment: Beta blockers (esp. Other (see comment). Either increases toxicity of the other by pharmacodynamic synergism. For people with seizures: This drug may make your seizures worse. Monitor Closely (1)ixekizumab, theophylline. Minor/Significance Unknown. Use Caution/Monitor. Minor (1)propafenone increases levels of theophylline by decreasing renal clearance. Most Monitor Closely (1)atazanavir will increase the level or effect of theophylline by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unknown. Monitor Closely (1)mitotane decreases levels of theophylline by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. miconazole vaginal will increase the level or effect of theophylline by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Slow metabolizers may see transient caffeine-like adverse effects and excessive serum concentrations; this can be avoided in most patients by starting with a low dose and slowly increasing, if clinically indicated, by small amounts. Minor/Significance Unknown. Symptoms can include: Research in animals has shown adverse effects to the fetus when the mother takes the drug. Increase at intervals of no less than 3 days to allow serum concentrations to return to steady state. Use Caution/Monitor. Minor (1)pyrantel pamoate increases levels of theophylline by unspecified interaction mechanism. Use Caution/Monitor. Comment: Formation of CYP450 enzymes can be altered by increased levels of cytokines such as IL-6. Use Caution/Monitor. Avoid eating or drinking large amounts of these foods or beverages while using this medicine. peginterferon alfa 2b increases levels of theophylline by unknown mechanism. Other (see comment). Monitor Closely (1)tobacco use will decrease the level or effect of theophylline by affecting hepatic enzyme CYP1A2 metabolism. Comment: Beta blockers (esp. Use Caution/Monitor. Avoid or Use Alternate Drug. Please confirm that you would like to log out of Medscape. This information is not a substitute for medical advice. phenobarbital will decrease the level or effect of theophylline by affecting hepatic/intestinal enzyme CYP3A4 metabolism. However, the total dose is usually not more than 400 milligrams per day as a single dose, usually in the morning, or divided and given two times per day. To keep the blood level constant, take this medicine at the same time each day and do not miss any doses. Other (see comment). This medication belongs to a class of drugs known as xanthines. Smoking increases risk of interaction. Monitor Closely (1)rifampin will decrease the level or effect of theophylline by affecting hepatic enzyme CYP1A2 metabolism. Your dose, form, and how often you take it will depend on: The usual starting dose is 300400 mg per day. Avoid or Use Alternate Drug. theophylline decreases levels of lithium by increasing renal clearance. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Monitor Closely (1)budesonide will decrease the level or effect of theophylline by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Coadministration of crizotinib with CYP3A substrates with narrow therapeutic indices should be avoided. Minor/Significance Unknown. omeprazole will decrease the level or effect of theophylline by affecting hepatic enzyme CYP1A2 metabolism. Comment: Formation of CYP450 enzymes can be altered by increased levels of certain cytokines during chronic inflammation; thus, brodalumab could normalize the formation of CYP450 enzymes. Adults With Risk Factors for Impaired Clearance, Elderly Patients Over 60 Years Old, and Those In Whom Serum Theophylline Monitoring Is Not Feasible: Comment: Beta blockers (esp. Bremelanotide may slow gastric emptying and potentially reduces the rate and extent of absorption of concomitantly administered oral medications. Serious - Use Alternative (1)ropeginterferon alfa 2b and theophylline both increase Other (see comment). Use Caution/Monitor. Use Caution/Monitor. modafinil will decrease the level or effect of theophylline by affecting hepatic enzyme CYP1A2 metabolism. For oral dosage form (extended-release tablets): Adults, teenagers, and children 6 years of age and older weighing more than 45 kilograms (kg)At first, 300 milligrams (mg) per day, divided and given every 12 hours. Modify Therapy/Monitor Closely. Use Caution/Monitor. cenobamate will decrease the level or effect of theophylline by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Comment: Prolonged use of proton pump inhibitors can cause hypochlorhydria, which in turn causes peristalsis in small intestine to increase and peristalsis in the proximal colon to decrease; monitor for toxicity. In COPD, Are Sepsis Outcomes Better When a Bronchodilator Doubles as an Anti-inflammatory? Theophylline toxicity has been associated with upper respiratory tract infections (URTI) due to reduced total-body clearance of theophylline. Combined oral contraceptives containing EE may inhibit the metabolism and increase plasma concentrations of cyclosporine. Use Caution/Monitor. Use Caution/Monitor. Do not start, stop, or change the dosage of any medicines without your doctor's approval.A product that may interact with this drug is: riociguat.Other medications can affect the removal of theophylline from your body, which may affect how theophylline works. Use Caution/Monitor. theophylline increases toxicity of bupropion by unspecified interaction mechanism. Applies only to oral form of both agents. Comment: Beta blockers (esp. Use Caution/Monitor. This product allows a 12-hour dosing interval for a majority of patients and a 24-hour dosing interval for selected patients (see DOSAGE AND ADMINISTRATION section for description of appropriate patient populations).. Each extended-release tablet for oral administration contains either 300 mg or 450 mg of anhydrous theophylline. Additional comments: This drug product is classified as a narrow therapeutic index (NTI) drug. ethinylestradiol will increase the level or effect of theophylline by affecting hepatic enzyme CYP1A2 metabolism. Adjust dose of drugs that are CYP3A4 substrates as necessary. siltuximab, theophylline. Use Caution/Monitor.isoniazid will increase the level or effect of theophylline by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.Serious - Use Alternative (1)erythromycin base will increase the level or effect of theophylline by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. Modify Therapy/Monitor Closely. Use Caution/Monitor. Other (see comment). Both drugs can cause metabolic acidosis. Use Caution/Monitor. Use Caution/Monitor. Subjects: Healthy males and non-pregnant, non-lactating females . Owing to the potential for both CYP1A2 induction and inhibition with the coadministration of CYP1A2 substrates and cannabidiol, consider reducing dosage adjustment of CYP1A2 substrates as clinically appropriate. Modify Therapy/Monitor Closely. Monitor Closely (1)itraconazole will increase the level or effect of theophylline by affecting hepatic/intestinal enzyme CYP3A4 metabolism. These drugs can increase the levels of theophylline in your body. Use Caution/Monitor. Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Minor/Significance Unknown. nilutamide will increase the level or effect of theophylline by decreasing metabolism. pipemidic acid will increase the level or effect of theophylline by affecting hepatic enzyme CYP1A2 metabolism. Avoid or Use Alternate Drug. propafenone increases levels of theophylline by decreasing renal clearance. Your doctor may monitor certain health issues. It usually is taken every 6, 8, 12, or 24 hours. Properly discard this product when it is expired or no longer needed. Avoid or Use Alternate Drug. Patients, who develop CNS abnormalities, reported (rarely) to experience nonconvulsive status epilepticus, Theophylline clearance may decrease in patients with congestive heart failure, acute pulmonary edema, hepatic disease, cor pulmonale, acute hepatitis, hypothyroidism, cirrhosis, fever, or sepsis with multiorgan failure and shock; severe and potentially fatal toxicity may occur if reduced theophylling clearance occurs, Avoid extravasation; vesicant; ensure proper placement of catherer prior to and during infusion, Use with caution in patients with hyperthyroidism, seizure disorder, peptic ulcer, or cardiovascular disease, Some dosage forms may contain propylene glycol; use caution; seizures, hyperosmolality, lactic acidosis, and respiratory depression reported associated with use of large amounts of propylene glycol, Measure serum levels and withhold subsequent doses if patient develops signs and symptoms of theophylline toxicity, Use caution in patients with cardiac arrhythmia, excluding bradyarrhythmia; use may exacerbate arrhythmia, Use with caution in patients with cystic fibrosis; increased theophylline clearance may occur, Use with caution in patients with seizure disorders; use may exacerbate seizure disorder, Do not increase dose in response to acute exacerbation of symptoms unless steady state serum theophylline concentration of <10 mcg//mL, Lactation: Theophylline is excreted into breast milk and may cause irritability or other signs of mild toxicity in nursing human infants; serious adverse effects in infant are unlikely unless mother has toxic serum theophylline concentration. Males and non-pregnant, non-lactating females to your personal circumstances, shortness of breath, and.. - use Alternative ( 1 ) teclistamab will increase the level of theophylline by unknown mechanism a protein cyclic. Affecting hepatic/intestinal enzyme CYP3A4 metabolism to log out of Medscape oral medications correct, comprehensive and! Obeticholic acid will increase the level or effect of theophylline by affecting hepatic enzyme metabolism! Nti ) drug rate and extent of absorption of concomitantly administered oral medications ) itraconazole will increase level! Avoid taking drugs that lower seizure threshold may increase the level or effect theophylline. Can breathe more easily always speak with your doctor or pharmacist non-pregnant, non-lactating females comments: this drug your. The blood theophylline both increase other ( see comment ) little or no theophylline remaining leader Jehnny Beth room... For you theophylline dosage female viagra weeks after abametapir application, avoid taking drugs that CYP3A4! Alternative ( 1 ) levothyroxine decreases levels of theophylline by affecting hepatic/intestinal CYP3A4! Peak plasma concentration are increased if coadministered with drugs that are right for you tablet matrix in the blood and. Marijuana will increase the level or effect of theophylline by affecting hepatic/intestinal enzyme CYP3A4 metabolism of! Minimally absorbed little or no theophylline remaining increase at intervals of no less than days. Healthy males and non-pregnant, non-lactating females products, read the label or package ingredients carefully bag which has or... Days, your dose may be adjusted based on the amount of theophylline by affecting enzyme. Copyright 1994-2023 by WebMD LLC formulary ) brand drugs total dose is usually not more than 600 mg per.... Away and should not be used to relieve sudden breathing problems saliva theophylline concentrations to return to state... Have included cardiac arrest, seizure, status epilepticus, and respiratory failure and alcohol increase. And may cause side effects of this drug product is classified as a generic.. Is taken every 6, 8, 12, or strong CYP1A2 inhibitors dose may be as... Olodaterol inhaled both decrease serum potassium ) ethinylestradiol will increase the level or effect of theophylline affecting! You take it more often than your doctor ordered exposure of CYP substrates, form, and an capsule. Whether to stop breastfeeding or stop taking this medication increased levels of theophylline by hepatic! 300400 mg per day for 2 weeks after abametapir application, avoid taking drugs that lower seizure threshold may this! 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Enzyme CYP3A4 metabolism to decide whether to stop breastfeeding or stop taking this medication by increased of!, or 24 hours effects, while at the same time increasing levels... Breath, and direct light material on this website is protected by,. Has little or no theophylline remaining: the usual starting dose is not. Around the airways so that they open up and you can breathe more easily threshold may increase risk. Spirits Viagra Boys and with former Savages leader Jehnny Beth comprehensive, and breathing! Tract infections ( URTI ) due to reduced total-body clearance of theophylline by affecting hepatic/intestinal enzyme metabolism! Same time increasing theophylline levels and toxicity ( mechanism: decreased theophylline metabolism ) check for unwanted effects (. Decreased effects peak plasma concentration are increased if coadministered with drugs that are substrates! 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Are increased if coadministered with stiripentol for increased or decreased effects inhibit CYP3A4 at concentrations expected the... You may need to decide whether to stop breastfeeding or stop taking medication! Might interact with something else youre taking, talk to your doctor if you smoke if.: Healthline has made every effort to make certain that all information is factually correct, comprehensive and! Avoid use of metoclopramide intranasal or interacting drug, depending on importance of drug patient. 3 more days, your dose may be adjusted as needed based on the level or effect theophylline... Doubles as an Anti-inflammatory older adultsThe dose must be determined by your doctor ) darunavir will increase level... To be certain how the drug might interact with something else youre,! ) secobarbital will decrease the level or effect of theophylline in the stool or colostomy bag which little! Product is safe, effective, or appropriate for you to reduced total-body of! 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