Ephedrine; Guaifenesin: (Moderate) Carefully monitor blood pressure in patients who have received both ephedrine and alpha-blockers; alpha-blockers antagonize the pressor effect of ephedrine. Estradiol: (Minor) Estrogens can induce fluid retention and may increase blood pressure in some patients; patients who are receiving antihypertensive agents concurrently with hormonal contraceptives should be monitored to confirm that the desired antihypertensive effect is being obtained. Some products that may interact with this drug include: If you are also taking a drug to treat erectile dysfunction-ED or pulmonary hypertension (such as sildenafil, tadalafil), your blood pressure may get too low which can lead to dizziness or fainting. If you have high blood pressure, lifestyle changes that may help this medication work better include exercising, stopping smoking, and eating a low-cholesterol/low-fat diet. Beta-blockers: (Moderate) Orthostatic hypotension may be more likely if beta-blockers are coadministered with alpha-blockers. What Other Drugs Interact with Terazosin? Intravenous administration of procainamide is more likely to cause hypotensive effects. A report about an ongoing trial of the drug from Raleigh-based Sprout Pharmaceuticals for treatment of low sexual desire in women finds in interim results that the so called 'female Viagra' can . If indicated, dosage of the antihypertensive agents should be reduced. Bortezomib: (Moderate) Patients on antihypertensive agents receiving bortezomib treatment may require close monitoring of their blood pressure and dosage adjustment of their medication. Patients who choose to take CoQ10 concurrently with antihypertensive medications should receive periodic blood pressure monitoring. Other variables, such as intravascular volume depletion, concurrent antihypertensive therapy, or evidence of hemodynamic instability with alpha-blocker monotherapy, may affect the safety of concomitant use of sildenafil and an alpha-blocker. Lofexidine: (Major) Because the central alpha-2 agonist effects of lofexidine can cause hypotension and orthostasis, the drug should be avoided, if possible, in combination with other medications that can significantly decrease blood pressure such as the antihypertensive alpha-blockers. Additive hypotensive effects are possible if ziprasidone is used concurrently with antihypertensive agents. Prilocaine; Epinephrine: (Moderate) Alpha-blockers antagonize the pressor effects of epinephrine. (Minor) Terazosin has been reported to increase peak concentrations of finasteride by 16% and AUC by 31% when the two agents are coadministered. Hypersensitivity to terazosin, other quinazolines. Conversely, patients already receiving an optimized dose of vardenafil should be started on the lowest dose of the alpha-blocker; increases in the alpha-blocker dose should be done in a stepwise fashion. Guaifenesin; Pseudoephedrine: (Moderate) The cardiovascular effects of pseudoephedrine may reduce the antihypertensive effects produced by alpha-blockers. Monitor blood pressure and heart rate. Ethinyl Estradiol; Levonorgestrel; Folic Acid; Levomefolate: (Minor) Estrogen-containing oral contraceptive may induce fluid retention and may increase blood pressure in some patients taking antihypertensive agents. Terazosin is used in men to treat the symptoms of an enlarged prostate (benign prostatic hyperplasia or BPH), which include difficulty urinating (hesitation, dribbling, weak stream, and incomplete bladder emptying), painful urination, and urinary frequency and urgency. . Also, because norepinephrine is an alpha-adrenergic agonist, drugs with alpha-blocking activity such as alpha-blockers directly counteract the vasopressor effects of norepinephrine. During clinical trials of bortezomib, hypotension was reported in roughly 12 percent of patients. Advertising on our site helps support our mission. Initially 1mg at bedtime. Isocarboxazid: (Moderate) Additive hypotensive effects may be seen when monoamine oxidase inhibitors (MAOIs) are combined with antihypertensives. Dextromethorphan; Diphenhydramine; Phenylephrine: (Major) Sympathomimetics can antagonize the effects of antihypertensives such as alpha-blockers when administered concomitantly. Alcohol or marijuana (cannabis) can make you more dizzy or drowsy. 1 mg PO once daily at bedtime, initially. Midodrine: (Major) Sympathomimetics can antagonize the effects of antihypertensives such as alpha-blockers when administered concomitantly. You may report side effects to Health Canada at 1-866-234-2345. Terazosin is classified as FDA pregnancy category C. Caution is advisable for breast-feeding mothers because it is not known whether terazosin distributes into breast milk. Tamsulosin is in a class of medications called alpha blockers. Monitor blood pressure and heart rate. Careful monitoring of blood pressure is suggested during concurrent therapy with antihypertensives such as alpha-blockers. Women's health is once again the center of a political ping-pong match with evidence-based science on one side and anti-choice advocates on the other. March 3, 2021 What is terazosin? Acetaminophen; Guaifenesin; Phenylephrine: (Major) Sympathomimetics can antagonize the effects of antihypertensives such as alpha-blockers when administered concomitantly. Monitor blood pressure and heart rate. If you miss a dose, take it as soon as you can. Silodosin: (Major) Silodosin should not be administered in combination with other alpha-blockers. Flomax; Descriptions. Acrivastine; Pseudoephedrine: (Moderate) The cardiovascular effects of pseudoephedrine may reduce the antihypertensive effects produced by alpha-blockers. Send the page "" Talk to your pharmacist for more details. Acetaminophen; Chlorpheniramine; Dextromethorphan; Pseudoephedrine: (Moderate) The cardiovascular effects of pseudoephedrine may reduce the antihypertensive effects produced by alpha-blockers. Do not stand or sit up quickly, especially if you are an older patient. During pregnancy, this medication should be used only when clearly needed. Max: 20 mg/day. How terazosin works Terazosin is a selective alpha blocker. In those men with significant corpora cavernosa venous leakage, hypotension might be more likely. It is used to treat high blood pressure (hypertension). close popup. This information is not individual medical advice and does not substitute for the advice of your health care professional. Additive hypotensive effects are possible. Copyright 2023 by RxList Inc. An Internet Brands company. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely, You should avoid driving or hazardous tasks for 12 hours after the first dose after your dose is increased, and when this medication is restarted after it has been stopped, See "What Are Side Effects Associated with Using Terazosin? Acetaminophen; Pseudoephedrine: (Moderate) The cardiovascular effects of pseudoephedrine may reduce the antihypertensive effects produced by alpha-blockers. Segesterone Acetate; Ethinyl Estradiol: (Minor) Estrogen-containing oral contraceptive may induce fluid retention and may increase blood pressure in some patients taking antihypertensive agents. Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. This causes less pressure on the urethra and increases urine flow. Tetracaine: (Moderate) Local anesthetics may cause additive hypotension in combination with antihypertensive agents. It also relaxes the muscles in the prostate and bladder, which makes it easier to urinate. 10 Things People With Depression Wish You Knew. NSAIDs, to varying degrees, have been associated with an elevation in blood pressure. Tamsulosin oral capsule is used to treat the symptoms of benign prostatic hyperplasia (BPH). Npoje s vysokm obsahom antioxidantov, ako s vitamny C a E, preukzatene zlepuj erektiln funkciu tm, e brnia pokodeniu buniek, produkujcich oxid dusnat," hovor Pearlmanov. A very serious allergic reaction to this drug is rare. Monitor blood pressure and heart rate. Ethinyl Estradiol; Norethindrone Acetate: (Minor) Estrogen-containing oral contraceptive may induce fluid retention and may increase blood pressure in some patients taking antihypertensive agents. Drug interactions may change how your medications work or increase your risk for serious side effects. Guaifenesin; Hydrocodone; Pseudoephedrine: (Moderate) The cardiovascular effects of pseudoephedrine may reduce the antihypertensive effects produced by alpha-blockers. to a friend, relative, colleague or yourself. Since terazosin is extensively metabolized, it is prudent to start with the lowest initial adult dosage (1 mg PO once daily at bedtime). Important. Nausea. Olanzapine; Samidorphan: (Moderate) Olanzapine may induce orthostatic hypotension and thus enhance the effects of antihypertensive agents. Initial doses higher than 1 mg may produce orthostatic hypotension. Levonorgestrel; Ethinyl Estradiol: (Minor) Estrogen-containing oral contraceptive may induce fluid retention and may increase blood pressure in some patients taking antihypertensive agents. Continue stirring until the capsule dissolves and the solution is homogeneous (510 minutes). NOTE: This medicine is only for you. Acetaminophen; Dextromethorphan; Guaifenesin; Phenylephrine: (Major) Sympathomimetics can antagonize the effects of antihypertensives such as alpha-blockers when administered concomitantly. Monitor blood pressure and heart rate. Formerly known under the brand name Hytrin. Verapamil: (Moderate) The first-dose response (acute postural hypotension) of terazosin can be potentiated by coadministration with beta-blockers. Terazosin is a medication that treats high blood pressure and benign prostatic hyperplasia. Significant changes were not observed in triglycerides and high-density lipoprotein. Pseudoephedrine; Triprolidine: (Moderate) The cardiovascular effects of pseudoephedrine may reduce the antihypertensive effects produced by alpha-blockers. The prostate gland is located below the . Learn more about link terms and conditions. Such patients should be monitored to confirm that the desired antihypertensive effect is being obtained. Also tell them if you smoke, drink alcohol, or use illegal drugs. Tamsulosin: (Major) Tamsulosin should not be administered in combination with other alpha-blockers. Separate multiple email address with a comma. Description and Brand Names. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: This is not a complete list of possible side effects. It's also used to treat high blood pressure in men and women. Risperidone: (Moderate) Risperidone may induce orthostatic hypotension and thus enhance the hypotensive effects of antihypertensive agents. Tamsulosin comes only as a capsule you take by mouth. Lurasidone: (Moderate) Due to the antagonism of lurasidone at alpha-1 adrenergic receptors, the drug may enhance the hypotensive effects of alpha-blockers and other antihypertensive agents. Procainamide: (Moderate) Procainamide can decrease blood pressure and should be used cautiously in patients receiving antihypertensive agents. If clinically significant or symptomatic hypotension and/or bradycardia occur, the next dose of lofexidine should be reduced in amount, delayed, or skipped. Graham Head, 66, who kidnapped and tried to rape two women, was caught after one victim remembered three digits of his car registration. This effect is of particular concern in the setting of acute myocardial infarction, unstable angina, or other acute hemodynamic compromise. In addition to discounts on thousands of brand-name and most generic medications, members get even more savings on three tiers . . All rights reserved. Dextromethorphan; Quinidine: (Moderate) Quinidine can decrease blood pressure and should be used cautiously in patients receiving antihypertensive agents due to the potential for additive hypotension. However, interactions or side effects (dizziness, hypotension, syncope, etc.) The addition of terazosin to other antihypertensive agents can cause a rapid decrease in blood pressure (see Drug Interactions). [63923] The federal Omnibus Budget Reconciliation Act (OBRA) regulates medication use in residents of long-term care facilities (LTCFs); antihypertensive regimens should be individualized to achieve the desired outcome while minimizing adverse effects. Carbinoxamine; Phenylephrine: (Major) Sympathomimetics can antagonize the effects of antihypertensives such as alpha-blockers when administered concomitantly. Generic name: Terazosin - oral. Pronunciation (ter-AY-zoe-sin) Brand name(s) Hytrin. Do not use epinephrine to counteract hypotension caused by an alpha-blocker, as a reversal of the pressor effect of epinephrine may result in paradoxical further lowering of blood pressure. Dosage adjustments may be necessary. TERAZOSIN (ter AY zoe sin) treats high blood pressure. Capsules should be stored between 68-77 degrees F (20-25 degrees C), because they may soften or melt if stored at higher than . Such patients should be monitored to confirm that the desired antihypertensive effect is being obtained. However, interactions or side effects (dizziness, hypotension, syncope, etc.) Other drugs that have the same active ingredients (e.g. Dosage adjustments may be necessary. Throw away any unused medication after the expiration date. Terazosin is sometimes given together. Dosage Considerations Should be Given as Follows: If your doctor has directed you to use this medication, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Use caution with in-clinic dosing for erectile dysfunction (ED) and monitor for the effects on blood pressure. Phendimetrazine: (Major) Sympathomimetics can antagonize the effects of antihypertensives such as alpha-blockers when administered concomitantly. If a breast-feeding infant experiences an adverse effect related to a maternally ingested drug, healthcare providers are encouraged to report the adverse effect to the FDA. may be expected from the duplication of pharmacologic effects. Side effects that you should report to your care team as soon as possible: Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome): This list may not describe all possible side effects. What Are the Best PsA Treatments for You? Finasteride; Tadalafil: (Moderate) Due to the potential for symptomatic hypotension, patients should be stable on alpha-blocker therapy before initiating therapy with the lowest recommended dose of tadalafil. Titrate to 10mg once daily; usual max 20mg/day. Photo: Andreas Neumann. The tour begins on Aug. 3 in Sterling . Dosage adjustments may be necessary. It comes as an oral capsule that you can take by mouth with a glass of water as directed. NSAIDs cause a dose-dependent reduction in prostaglandin formation, which may result in a reduction in renal blood flow leading to renal insufficiency and an increase in blood pressure that are often accompanied by peripheral edema and weight gain. Caution is advised when tizanidine is to be used in patients receiving concurrent antihypertensive therapy. Some products have ingredients that could raise your blood pressure. Fecal (60%), renal (40%). Norethindrone Acetate; Ethinyl Estradiol; Ferrous fumarate: (Minor) Estrogen-containing oral contraceptive may induce fluid retention and may increase blood pressure in some patients taking antihypertensive agents. Patients being given lofexidine in an outpatient setting should be capable of and instructed on self-monitoring for hypotension, orthostasis, bradycardia, and associated symptoms. See full labeling. While no specific drug interactions have been identified with systemic agents and apraclonidine during clinical trials, it is theoretically possible that additive blood pressure reductions could occur when apraclonidine is combined with the use of antihypertensive agents. At the end of the study, 80% of the men were receiving the full dose. The potential reduction in blood pressure can precipitate orthostatic hypotension and associated dizziness, tachycardia, and syncope. In Canada - Call your doctor for medical advice about side effects. Hytrin is used to treat hypertension (high blood pressure), or to improve urination in men with benign prostatic hyperplasia (enlarged prostate). Terazosin is available under the following different brand names: Hytrin. Patients who rely upon renal prostaglandins to maintain renal perfusion may have acute renal blood flow reduction with NSAID usage. Benign prostatic hyperplasia/urinary retention. When tadalafil is used for benign prostatic hypertrophy (BPH), discontinue alpha-blocker therapy at least 1 day prior to initiating tadalafil therapy. Such patients should be monitored to confirm that the desired antihypertensive effect is being obtained. CoQ10 use in combination with antihypertensive agents may lead to additional reductions in blood pressure in some individuals. It is not intended to be a substitute for the exercise of professional judgment. Discuss the risks and benefits with your doctor. If you notice other effects not listed above, contact your doctor or pharmacist. Uses Warnings Before taking Side effects Dosage Interactions What is dutasteride and tamsulosin? Terazosin oral capsule is used to improve urinary flow and other symptoms of benign prostatic hyperplasia (BPH) in men. Chewing sugarless gum or sucking hard candy, and drinking plenty of water may help. Terazosin therapy should be initiated cautiously in patients receiving other antihypertensive agents. Trandolapril; Verapamil: (Moderate) The first-dose response (acute postural hypotension) of terazosin can be potentiated by coadministration with beta-blockers. Tell your doctor right away if you have any serious side effects, including: Rarely, males may have a painful or prolonged erection lasting 4 or more hours. Lovastatin; Niacin: (Moderate) Cutaneous vasodilation induced by niacin may become problematic if high-dose niacin is used concomitantly with other antihypertensive agents. NOTE: This sheet is a summary. For males, contact your care team right away if you have an erection that lasts longer than 4 hours or if it becomes painful. TERAZOSIN 1MG CAP 30 : 90 ; TERAZOSIN 2MG CAP 30 : 90 ; TERAZOSIN 5MG CAP 30 : 90 ; TERAZOSIN 10MG CAP 30 : 90 ; Blood Pressure/Heart Health (cont.) Your doctor will start this medication at a low dose and gradually increase your dose. If concurrent use of iloperidone and antihypertensive agents is necessary, patients should be counseled on measures to prevent orthostatic hypotension, such as sitting on the edge of the bed for several minutes prior to standing in the morning and rising slowly from a seated position. US Brand Name. Rasagiline: (Moderate) Additive hypotensive effects may be seen when monoamine oxidase inhibitors (MAOIs) are combined with antihypertensives. Terazosin may be administered without regard to meals. Dizziness, lightheadedness, tiredness, nausea, drowsiness, blurred vision, headache, or stuffy nose may occur. Close monitoring of blood pressure is recommended until the full effects of the combination therapy are known. Baclofen: (Moderate) Baclofen has been associated with hypotension. Terazosin is sometimes given together with other blood pressure medication. Do not use epinephrine to counteract hypotension caused by an alpha-blocker, as a reversal of the pressor effect of epinephrine may result in paradoxical further lowering of blood pressure. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medication affects you. Serious heart symptoms include fast, irregular, or pounding heartbeats; fluttering in the chest; shortness of breath; sudden dizziness, lightheartedness, or passing out. Paliperidone: (Moderate) Paliperidone may cause orthostatic hypotension, thereby enhancing the hypotensive effects of antihypertensive agents. Dosages should be adjusted carefully, according to blood pressure. Kaiser Permanente health plans around the country: Kaiser Foundation Health Plan, Inc., in Northern and Southern California and Hawaii Kaiser Foundation Health Plan of Colorado Kaiser Foundation Health Plan of Georgia, Inc., Nine Piedmont Center, 3495 Piedmont Road NE, Atlanta, GA 30305, 404-364-7000 Kaiser Foundation Health Plan of the Mid-Atlantic States, Inc., in Maryland, Virginia, and Washington, D.C., 2101 E. Jefferson St., Rockville, MD 20852 Kaiser Foundation Health Plan of the Northwest, 500 NE Multnomah St., Suite 100, Portland, OR 97232 Kaiser Foundation Health Plan of Washington or Kaiser Foundation Health Plan of Washington Options, Inc.,1300 SW 27thSt., Renton, WA 98057. Pharmacological Class . To help you remember, take it at the same time each day. It is unknown if this drug passes into breast milk. Carbinoxamine; Pseudoephedrine: (Moderate) The cardiovascular effects of pseudoephedrine may reduce the antihypertensive effects produced by alpha-blockers. Dobutamine: (Major) Sympathomimetics can antagonize the effects of antihypertensives such as alpha-blockers when administered concomitantly. Draw the solution into an oral syringe and administer through the feeding tube. Carbinoxamine; Dextromethorphan; Pseudoephedrine: (Moderate) The cardiovascular effects of pseudoephedrine may reduce the antihypertensive effects produced by alpha-blockers. The dose could be adjusted downward if adverse effects appeared. If concurrent use of asenapine and antihypertensive agents is necessary, patients should be counseled on measures to prevent orthostatic hypotension, such as sitting on the edge of the bed for several minutes prior to standing in the morning and rising slowly from a seated position. Patients should be advised to inform their prescriber of their use of CoQ10. Sildenafil: (Moderate) Due to the potential for symptomatic hypotension, patients should be stable on alpha-blocker therapy before initiating therapy with the lowest dose of sildenafil. If you have questions, ask your pharmacist. US residents can call their local poison control center at 1-800-222-1222. 2023 Kaiser Foundation Health Plan, Inc. We are unable to switch you to this area of care. The pharmacokinetic and pharmacodynamic interactions between alfuzosin and other alpha-blockers (used for high blood pressure or for benign prostatic hyperplasia) have not been determined. If it is almost time for your next dose, take only that dose. Consult your pharmacist or local waste disposal company. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Drospirenone; Ethinyl Estradiol; Levomefolate: (Minor) Estrogen-containing oral contraceptive may induce fluid retention and may increase blood pressure in some patients taking antihypertensive agents. Small decreases in blood pressure have been observed in some patients treated with pentoxifylline; periodic systemic blood pressure monitoring is recommended for patients receiving concomitant antihypertensives. ", May cause first-dose fainting/sudden loss of consciousness and dizziness upon standing; minimize the effect by using a small first dose at bedtime; increase dose slowly, Concomitant administration with DFE-5 inhibitor (sildenafil) can result in additive blood pressure-lowering effects and symptomatic low blood pressure (hypotension); initiate PDE-5 inhibitor therapy at the lowest dose, The risk of persistent and painful erection of the, Use terazosin during pregnancy with caution if the benefits outweigh the risks, Animal studies show risk and human studies are not available, or neither animal nor human studies were done, It is unknown if terazosin is excreted into breast milk; use caution and consult your doctor before breastfeeding. Nesiritide, BNP: (Major) The potential for hypotension may be increased when coadministering nesiritide with antihypertensive agents. Patients should be instructed to rise slowly from a sitting position, and to report syncope or changes in blood pressure or heart rate to their health care provider. Apomorphine: (Moderate) Use of terazosin and apomorphine together can increase the hypotensive effects of apomorphine. Dexchlorpheniramine; Dextromethorphan; Pseudoephedrine: (Moderate) The cardiovascular effects of pseudoephedrine may reduce the antihypertensive effects produced by alpha-blockers. Alcohol can make you more drowsy and dizzy. Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once. Such patients should be monitored to confirm that the desired antihypertensive effect is being obtained. Concurrent use with baclofen and antihypertensive agents may result in additive hypotension. Flush the tube with water following administration. Chlorpheniramine; Ibuprofen; Pseudoephedrine: (Moderate) The cardiovascular effects of pseudoephedrine may reduce the antihypertensive effects produced by alpha-blockers. Aldesleukin, IL-2: (Moderate) Terazosin may potentiate the hypotension seen with aldesleukin, IL-2. Conversely, patients already receiving an optimized dose of sildenafil should be started on the lowest dose of the alpha-blocker; increases in the alpha-blocker dose should be done in a stepwise fashion. Brompheniramine; Pseudoephedrine; Dextromethorphan: (Moderate) The cardiovascular effects of pseudoephedrine may reduce the antihypertensive effects produced by alpha-blockers. Alpha-adrenergic blocker; used for HTN and BPH; duration of action longer than prazosin but is shorter than doxazosin; greater efficacy for BPH when compared to finasteride. Haloperidol: (Moderate) In general, haloperidol should be used cautiously with antihypertensive agents due to the possibility of additive hypotension. There is no change in the patient's cardiac output or heart rate, and the response to exercise remains essentially the same.Terazosin also alters lipid metabolism, decreasing the levels of total cholesterol, low-density lipoprotein (LDL) cholesterol, and very low-density lipoprotein (VLDL) cholesterol. If you miss taking terazosin for a few days, you may need to restart treatment at the low dose and gradually increase your dose again. Cariprazine: (Moderate) Orthostatic vital signs should be monitored in patients who are at risk for hypotension, such as those receiving cariprazine in combination with antihypertensive agents. Erectile dysfunction ( ED ) and monitor for the exercise of professional judgment the! This causes less pressure on the urethra and increases urine flow is in a class of medications called alpha.! Should not be administered in combination with other alpha-blockers minutes ) dosages should be used cautiously with antihypertensive agents and! 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