Diagnoses, management, ASIA grade, and complications varied across the four geriatric age groups. Available from: https://bur.regione.veneto.it/BurvServices/pubblica/DettaglioDgr.aspx?id=328301. Careers, Unable to load your collection due to an error. https://doi.org/10.1038/s41393-022-00795-w, DOI: https://doi.org/10.1038/s41393-022-00795-w. Examination of the diagnoses, management, ASIA grade, and complications of patients within the four geriatric age groups yielded important information regarding geriatric SCI care. These factors include susceptibility for fall-related injuries due to decreased neurological reserve, increased prevalence of cervical spinal stenosis with underlying myelopathy, and decline in bone mineral density (3). In 2016, the number of people in the U.S. with SCI was estimated at approximately 288,000 (4). By Glenn A. Gonzalez, MD, and James Harrop MD, MSQHS, FACS, Chair, ACS Advisory Council for Neurological Surgery. Progress in pre-hospital and hospital treatment have led to an improved survival and a consequent increase in prevalent cases with TSCIs. Suitable for: Compared to traffic crashes, injury rates for other causes (such as violence, self-harm etc. Accid Anal Prev. According to one study, when accounting for all age groups, 22% of SCI in the U.S. occurs in African-Americans (29). The effect of low-trauma fracture on one-year mortality rate among privately insured adults with and without neurodevelopmental disabilities. Diagnoses were sorted into: spine tumors and metastatic disease, fractures, central cord syndrome, disc herniation, cauda equina syndrome, epidural hematoma, unspecified myelopathy, or multiple diagnoses. ISSN 1476-5624 (online) Some people with spinal cord injuries have one of two types of muscle tone problems: uncontrolled tightening or motion in the muscles (spasticity) or soft and limp muscles lacking muscle tone (flaccidity). The most recent estimate of the annual incidence of traumatic spinal cord injury (SCI) is approximately *, N: 30 total complications; %: based on 24 total patients who had major complications only or major and minor complications. Traffic crashes and occupational accidents were not associated with any significantly increased risk of death. Criteria for surgery were unstable spine as determined on advanced imaging (magnetic resonance imaging or computed tomography). Finally, stratification for the cause of death was not performed due to low numbers, but overall mortality was an effective indicator of what characteristics of the patient and of the injury were more strongly associated with an increased risk of death. Before Proportional hazards assumption was verified by plotting Schoenfeld residuals. The data used for the present study cannot be shared publicly. First, electronic medical records were not fully complete in some patients, and nearly 50 records were not updated regarding mortality information. There were no significant differences in the distribution of decedents and survivors at one year based on the type of healthcare support provided, as reported in Table1. The https:// ensures that you are connecting to the TSCIs occurred most frequently due to traffic crashes (29.9%) and occupational accidents (29.8%). Traumatic spinal cord injury in Victoria, 20072016. Since these patients were managed by multiple providers from various medical specialties, there were no standard PRO used among the care teams during the study period. Chiu W-T, Lin H-C, Lam C, Chu S-F, Chiang Y-H, Tsai S-H, et al. Adjustment was performed by including all available covariates. Hospital discharge records and mortality records were used to identify patients and outcomes. Furthermore, this association of complications and severe ASIA grade was also evident in the 6569 age group, which had the highest rate of ASIA A SCI and both major and minor complications. Study design/setting: This is a retrospective multicenter cohort study. Second, there is a lack of diversity in demographics, as the vast majority of patients were Caucasian (86.8%), while only 7.5% of patients were African-American (the second-most common racial group in this study). Transverse myelitis (TM) is a rare inflammatory disease causing injury to the spinal cord with varying degrees of weakness, sensory alterations, and autonomic dysfunction (the part of the nervous system that controls involuntary activity, such as the heart, breathing, the digestive system, and reflexes). Available online. During the 10-year study period, from January 1, 2011 to December 31, 2020, 1303 incident cases of TSCI were identified. Learn more about injury expectations for . Among the 24 total patients who sustained major complications, 30 total counts of complications were reported (Table 5). Inclusion in an NLM database does not imply endorsement of, or agreement with, Ahoniemi E, Pohjolainen T, Kautiainen H. Survival after spinal cord injury in Finland. The term 'spinal cord injury' refers to damage to the spinal cord resulting from trauma (e.g. Global, regional, and national burden of traumatic brain injury and spinal cord injury, 19902016: a systematic analysis for the Global Burden of Disease Study 2016. National SCI Statistical Center 515 Spain Rehabilitation Center Nevertheless, given these types of accidents are frequently preventable and often affect younger individuals, they warrant public health efforts in promoting road and workplace safety policies. inability to move the arms or legs. Trends related to the specific cause and setting that led to the injury are reported in Table3. TSCIs were more common among males, with an overall male to female ratio of 2.3:1, as reported in Table2. Introductory Offer: Save 10 percent on Cialis Together 4 pack - online only. Mechanisms for SCI may be traumatic or non-traumatic. 2017;55:11037. Scand J Trauma Resusc Emerg Med. Existing literature has identified a growing need to further evaluate geriatric SCI given the countrys aging population. Clinical prediction model for acute inpatient complications after traumatic cervical spinal cord injury: a subanalysis from the Surgical Timing in Acute Spinal Cord Injury Study. Deliberazione della Giunta Regionale del Veneto n. 1239 del 01 agosto 2016: Istituzione della Rete regionale per il Trauma. The next most common diagnoses were central cord syndrome (28.3%), multiple diagnoses (11.3%) and disc herniation (7.5%). This is most likely due to inpatient complications, such as respiratory distress. Other leading causes of trauma-related SCI include motor vehicle accidents (MVA) and sports and recreation accidents (7). This could be partly explained by social and cultural differences in the present study population that maintain a significant differential risk between men and women. Life expectancy after spinal cord injury: a 50-year study. For Statistics: 205-934-3342 . Global prevalence and incidence of traumatic spinal cord injury. The use of halo immobilization in the nonoperative treatment of spinal fractures has also been associated with increased in-hospital mortality rates in patients older than 65 years (27,28). Annual TSCI incidence rate, both crude and age-sex-standardized, along with the 95% confidence interval (95% CI) were estimated per million inhabitants. All patients enrolled had traumatic spinal cord injuries of the cervical, thoracic, and/or lumbar spine. The two most common diagnoses of SCI were fractures (43.4%) and central cord syndrome (28.3%). Comorbidity and increased frailty are likely to play a role in this finding. There are wide geographical variations in the reported incidence, prevalence, as well as mortality related to TSCIs. Epidemiological Department, Azienda Zero, Veneto Region, Padua, Italy, Clinical Governance Unit, Azienda Zero, Veneto Region, Padua, Italy, Laura Salmaso,Stefania Bellio&Mario Saia, You can also search for this author in Finally, evaluating differences in hospital trajectories within the regional trauma network in relation to mortality risks, has provided evidence in support of the importance of a trauma network that allows to manage patients dynamically based on the individual complexity, adapting to possible changes in the clinical picture. 2 The rate of SCI in patients . As such, although there is an increased risk of SCI that comes with age, there may not be an increased severity of injury. In most countries, in fact, traffic crashes represent the most common cause of TSCIs [3]. Apr 1. The 6569 age group had the lowest rate of nonoperative care (46.2%), which may be due to the perceived risk of complications among older patients and ambiguity about optimal treatment for SCI, causing surgeons to deliberate for years before making a clear therapeutic decision. Annual trends in age-standardized incidence rates for traffic crashes and occupational accidents were also estimated grouped by sex. Traumatic Spinal Cord Injury in the United States, 1993-2012. Violence accounts for a relevant number of TSCIs in specific countries. Forty-six (86.8%) patients were Caucasian, 4 (7.5%) were African American, 1 (1.9%) was Asian, and 2 (3.8%) did not state their race. Sixty-six percent of traumatic SCI patients were male. Therefore, treatment for a spinal cord injury often begins at the . Given the presence of an efficient trauma network in the Region, patients were also classified based on the type of hospital support they received. Beck B, Cameron PA, Braaf S, Nunn A, Fitzgerald MC, Judson RT, et al. Review Paper: epidemiology of traumatic spinal cord injury: comparisons between developed and developing countries. The mean age at the time of the injury was 59.2 years (SD 21.4), spanning from 0 to 99 years (median age 62, IQR 4477 years), with a higher prevalence of male patients (68.3%). The geriatric population (65 years old) represents the fastest growing demographic in the United States (U.S.) (1). The main limitation of this paper is the absence of a clinical assessment of the severity of the spinal cord injury. Sex, cause of the trauma, or inpatient hospital management were not associated with an increased risk of death. Background: Incidence studies of spinal cord injury (SCI) are important for health-care planning and epidemiological research. cancer). The mean age at onset is 42 years, with an increasing number of individuals older than 60 years incurring traumatic . Heart rate. A paper published on Lancet Neurology in 2019, on the global burden of TSCI showed that males have divergent incidence patterns compared to women below 60 years, while these trends overlap in older age [1]. Over the study period the use of high dose steroids decreased. Article Summary of background data: GBD 2019 estimates the burden of 369 diseases and . This allows to optimize expenditure by centralizing highly specialized personnel and equipment for more complex and critical TSCI patients, without hindering the overall quality of care. The variability of estimates across countries can be partly explained by differences in terms of mechanism of injury, demographic characteristics of patients, as well as cultural and life-style differences [13]. Diagnoses retrieved from planned hospitalizations or admissions to rehabilitation facilities have been excluded from the analyses. Anyway, the stably higher incidence of TSCIs among men at all ages warrants further studies to examine whether sex may actually be a risk factor per se, in order to promote targeted public health policies addressed to men. Publishers note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. LS performed the analyses and contributed conceiving the study and study design, interpreting the results, and writing the manuscript. Middleton JW, Dayton A, Walsh J, Rutkowski SB, Leong G, Duong S, et al. Spinal Cord. The presence of an epidural process causing compression to the neural elements and associated neurological deficits was also criteria for surgery. 2014;2:1106. Long-term medical and productivity costs of severe trauma: Results from a prospective cohort study. Out of the 5 patients with ASIA C, 3 had central cord syndrome and 2 had fractures. Eight (15.1%) patients experienced traumatic SCI as a result of other trauma, such as being struck by an object. 2010;22:918. Sabre L, Rekand T, Asser T, Krv J. Mortality and causes of death after traumatic spinal cord injury in Estonia. Lancet Neurol. When analyzed as a covariate, age was categorized as 54, 5574, and 75 years. Third, there were no patient reported outcomes (PRO) collected for the SCI patients. Helps you get and maintain an erection when you need it. Available online: Seven-year survival following spinal cord injury. Using demographic data, patients were separated into four groups based on age (6569, 7074, 7579, and 80 years) to create four groups that are roughly equal in number (13, 16, 12, and 12, respectively). National Spinal Cord Injury Statistical Center. This condition is a leading cause of disability especially among younger people, with a high impact on years lived with disability [5, 6]. Eur Spine J. Spinal Cord 60, 812819 (2022). Most TSCIs were cervical lesions (52.1%), and the most common cause of injury were traffic crashes (29.9%) followed by occupational accidents (29.8%). TSCIs related to traffic crashes do not show any clear association with age, with a similar pattern to that observed for occupational accidents that peak at working ages. In an analysis restricted to 20162020, TSCIs due to falls, stably represented 33% to 35% of all TSCIs, with this proportion increasing to 48.5% in 2020 (data not shown). van den Berg MEL, Castellote JM, Mahillo-Fernandez I, de Pedro-Cuesta J. Muscle tone. Keywords Spinal cord injury Traumatic spine injury Neurogenic shock NEXUS Canadian c-spine rules Introduction It is estimated that the annual incidence of traumatic spinal injury (TSI) in the United States is approximately 40 per million of population, which equates to 12,000 new cases per year [1]. This review gives a quantitative update on SCI epidemiology worldwide through a statistical evaluation of incidence rates. J Rehabil Med. Our objective is to elucidate the demographics, diagnoses, mechanisms of injury, ASIA grade, management, complications, and mortality of traumatic SCI in geriatric patients, with specific examination of four age groups. Paganini M, Barbiellini Amidei C, Valastro MF, Favaro A, Saia M, Buja A Adult emergency department visits during the COVID-19 pandemic in Veneto region, Italy: a time-trend Analysis. 8600 Rockville Pike TSCIs due to traffic crashes in the present study showed a similar association with age as that observed for occupational accidents, and a similar pattern to that previously reported in literature, with the exception of stable or just slightly decreasing trends among older individuals [32]. 2021 Jul 30 [cited 2021 Dec 13]; Available from: https://link.springer.com/10.1007/s11739-021-02815-8. Nevertheless, given the devastating effect of TSCIs on individual quality of life and the burden on healthcare systems, public health efforts should be aimed at reducing its incidence [19]. The absence of differences in short- and long-term mortality risks based on the type of healthcare support provided within the regional trauma network is suggestive of an effective system, with a correct management of healthcare resources based on the stratification of patient needs. These injuries can result in paralysis, loss of feeling, chronic pain, and other serious medical problems below the site of the injury. Jain NB, Ayers GD, Peterson EN, Harris MB, Morse L, OConnor KC, et al. See details below, always read the label. These results are comparable with the ones reported in the present study, with the exception of older individuals, where sex-based differences persist. Non-traumatic causes include epidural abscesses, epidural hematomas, metastatic disease with epidural spinal cord compression, intradural tumors, and surgical complications (3,5). Previous works have also observed stable if not decreasing trends in TSCIs caused by road accidents [13, 29, 30]. No changes in mortality risks could be observed based on the study period (12-months adjusted mortality HR 1.02 (95% CI, 0.981.07)). Trends in the incidence rate of TSCI were also restricted to individuals aged 30 years, without observing any significant changes over time (p=0.1084) (data not shown). There is no reliable estimate of global prevalence, but estimated annual global incidence is 40 to 80 cases per million population. The National Spinal Cord Injury Database is a prospective longitudinal multicenter study that currently captures data from an estimated 6% of new SCI cases in the United States. Spinal cord injury (SCI) is a common event; in the United States, the incidence of traumatic SCI is approximately 54 per million persons per year, with approximately 280,000 living survivors of traumatic SCI in 2017 [].The prevalence of nontraumatic SCI is unknown, but it is estimated that it is three to four times greater than traumatic SCI []. ASIA, American Spinal Injury Association. Piano Socio Sanitario Regionale (PSSR) 20122016. Spinal Cord Injury Facts and Figures at a Glance 2012. In addition, fractures accounted for all 8 patients with ASIA A or ASIA B SCI. [29]. Regardless of the setting and anatomical level of the spinal cord injury, patients with TSCI are at increased risk of premature death [13, 33, 34]. Intraoperative and postoperative complications have previously been categorized as major and minor by Glassman and colleagues based on consensus agreement of study group surgeons (13). 2014;309. van der Vlegel M, Haagsma JA, Havermans RJM, de Munter L, de Jongh MAC, Polinder S, et al. Use the Previous and Next buttons to navigate the slides or the slide controller buttons at the end to navigate through each slide. The Burden of Traumatic Spinal Cord Injury in the United States: Disability-Adjusted Life Years - ScienceDirect [Internet]. Many things can cause SCI. The global map for traumatic spinal cord injury epidemiology: update 2011, global incidence rate. On average, hospital length of stay was just above 20 days, although among patients that died within the first 12 months of the injury, the length of stay was significantly greater, corresponding to an average of 25 days (p=0.0023). Given the preventable nature of occupational accidents, traffic crashes, and falls, that are leading causes of TSCIs, public health experts should monitor TSCI trends and identify groups at increased risk, to implement targeted prevention policies [19]. Thirteen (24.5%) patients were 6569 years of age, 16 (30.2%) were 7074, 12 (22.6%) were 7579, and 12 (22.6%) were 80 or older. Congressional Budget Office. J Neurol Neurosurg Psychiatry. Our study revealed that 67.9% of geriatric traumatic SCI was caused by falls, which is in line with other studies, some of which have reported falls accounting for as much as 77% of cases (15). 1997;146:26672. Historical Causes of Death Persons enrolled in the National SCI Database have now been followed up to 48 years after injury. Deliberazione della Giunta Regionale del Veneto n. 614 del 14/05/2019, Allegato E [Internet]. Patient sample: A total of 57,310 patients of TraumaRegister DGU (2002-2012) of the German Trauma . Jackson AB, Dijkers M, DeVivo MJ, Poczatek RB. J Am Coll Surg. In fact, one month after the injury, mortality rates for patients withhigh cervical lesions were almost twice those observed forpatientswith low cervical lesions (C5-C7), and about four times greater than those observed for patients withoutcervicalspinal cord lesions. These differences in tracheostomy requirement were believed to be due to decreased muscular protection of the airway, vital capacity, and reserve volumes (26). Epidemiology, demographics, and pathophysiology of acute spinal cord injury. Geriatric patients are more vulnerable to traumatic SCI than the general patient population due to various age-related factors. A spinal cord injury (SCI) is damage to the tight bundle of cells and nerves that sends and receives signals from the brain to and from the rest of the body. 4 UNI | 4.95 per 1UNI. Accid Anal Prev. Fehlings MG, Vaccaro A, Wilson JR, et al. Spinal Cord. In case of lesions at multiple levels, the patient was included in the group that corresponded to the most severe level of the lesion, from top to bottom. Based on the population registry, annual incidence rates were calculated using the resident population insured by the regional health service in Veneto Region during the study period, as denominator. Between 2011 and 2020, 1303 patients with incident TSCI were identified in a population of 4.9 million inhabitants. Seven hundred and fifty-seven SCI patients were identified and 53 met our inclusion criteria, with 35 (66.0%) males and 18 (34.0%) females (Table 1). The aging population and its impact on the surgery workforce. Effective up to 36 hours. The main strength of this paper is a relatively long observation period and a large study population that allowed to perform numerous subgroup analyses. Five (9.4%) patients sustained only major complications, 10 (18.9%) sustained only minor complications, and 19 (35.8%) had both major and minor complications (defined by Glassman et al.s criteria) (13). Federal government websites often end in .gov or .mil. According to the National Spinal Cord Injury Statistics Center (NSCISC), the annual incidence of SCI is approximately 54 cases per 1 million people in the US, or approximately 17,700 new SCI . Cardiovascular disease (CVD) has become a leading cause of morbidity and mortality in individuals with chronic spinal cord injury (SCI). Perioperative complications of anterior procedures on the spine. Therefore, this study evaluates the demographic and clinical characteristics of traumatic SCI within a geriatric population. Patients 80 years had the lowest overall rate of complications (50%). Urgent medical attention is critical to minimize the effects of head or neck trauma. diarrhea. All emergency department records and hospital discharge records from January 1, 2011, to December 31, 2020, were collected. Emergency department records database provides information on all emergency room visits and includes patient demographic data, reason for the visit, and a description of the type of trauma for visits due to traumatic injuries. To remove possible inpatient episodes of prevalent TSCI cases, the following exclusion criteria were applied: hospitalized patients with TSCI that were not present in the population registry, cases with a diagnosis of spinal column fracture without spinal cord injury, and patients with conditions indicative of a non-traumatic spinal cord injury (pathologic fracture of vertebrae (ICD-9-CM 733.13) or secondary malignant neoplasm of the bone and bone marrow (ICD-9-CM 198.5). Spinal cord infarction (SCI) accounts for up to 1% of all strokes 1 and can lead to severe disability, including paraplegia and tetraplegia. The average age was 74 years (range, 65 to 91 years). Occupational accidents and traffic crashes were not associated with higher adjusted mortality risks compared to injuries due to other causes or settings, similarly to what has been observed by Chamberlain et al. This may be due to riskier behavior in the younger geriatric patientsfor example, half of the youngest geriatric age group experienced traumatic SCI due to falls from height (e.g., off a ladder) or secondary to risky behaviors (e.g., snowmobiling, horse riding), both of which were not present in any patient 80 years. Falls from ladders: age matters more than height. The majority of studies showed a high male-to-female ratio and an age of peak incidence of younger than 30 years old. 5705185. Incidence trends of traumatic spinal cord injury and traumatic brain injury in Spain, 20002009. The type of healthcare support provided to the patient (highly specialized trauma center or spoke hospital) also did not modify the patients likelihood of dying. Patients with traumatic spinal cord injuries admitted to the inpatient rehabilitation unit of a level I trauma center from 2003 to 2013 were reviewed. Future studies with an accurate assessment of the severity of TSCIs are warranted to better understand the importance of the type of healthcare support received within the trauma network. Studies with a complete and long-term assessment of the burden of TSCIs comprising outcomes and costs related to rehabilitation and disability are also needed to have a complete picture of the impact of TSCIs on public health systems. Out of the 40 patients with ASIA D, 2 had spinal mass, 1 had unspecified myelopathy, 13 had central cord syndrome, 1 had epidural hematoma, 4 had disc herniation, 1 had cauda equina syndrome, 13 had fractures, and 5 had multiple diagnoses. Spinal cord MRI findings in traumatic spinal cord injury (tSCI) and nontraumatic spinal cord injury the most common form of which is degenerative cervical myelopathy (DCM) have. Mortality rates were greater for cervical lesions, and increased with age, remaining stably high among older individuals even 12 months after the accident. Patients 65 years of age and older, with complete medical records, and undergoing surgical or nonsurgical treatment for traumatic SCI at a level 1 trauma center from January 2003 to December 2013 were identified and enrolled. Previous studies have noted that falls are the predominant mechanism of SCI in patients older than 45 years. Spinal Cord. The incidence of cervical, thoracic, and lumbar or sacral injuries, varies a lot in previous literature [3, 29]. Google Scholar. Google Scholar. Recent advances in managing a spinal cord injury secondary to trauma. Here, we investigated a case of a male individual with complete thoracic spinal cord injury who presented with a rare form of self-sustained rhythmic spinal myoclonus in the legs and rhythmic . Was 21.99. Univariate and bivariate analyses were performed to summarize data with respect to the patient demographic and TSCI characteristics. a car crash) or from disease or degeneration (e.g. E-mail: NSCISC@uab.edu Website: uab.edu/NSCISC. Spinal Cord. Neuroepidemiology.2015;44:18298. Spinal Cord Injury Facts and Figures at a Glance 2016. Incidence The 2021 population size in the United States was estimated to be about 333 million people. The regional mortality database includes information relating to any death that occurred in the Region. Considering that the incidence of traumatic SCI in the elderly is increasing, the aging of the general (U.S.) population will greatly influence the future of spine trauma and spine rehabilitation centers (3,15). Rising Demand for Long-Term Services and Supports for Elderly People, 2013. Public health policies should aim at reducing preventable TSCIs, and special attention should be drawn to long-term management of elderly patients in the attempt to decrease mortality rates. Furthermore, given the burden of mortality related to TSCIs, both the characteristics of the trauma and the type of healthcare support provided to patients should be examined to determine the characteristics that are associated with better outcomes in terms of short- and long-term mortality. All statistical analyses were conducted using SAS (Statistical Analysis System) software version 9.4 (SAS Institute Inc., Cary, NC, USA). Acute spinal cord injury (SCI) is due to a traumatic injury that bruises, partially tears, or completely tears the spinal cord. 2006;44:5239. 2019;18:5687. The current US prevalence is estimated at 282,000 persons. ASIA B: a sensory incomplete injury with complete motor function loss. 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