Review our medical disclaimer. Nymalize: 30 mg/10 mL (10 mL); 60 mg/20 mL (20 mL, 473 mL) [contains alcohol, usp, methylparaben, polyethylene glycol], Nimodipine shares the pharmacology of other calcium channel blockers; animal studies indicate that nimodipine has a greater effect on cerebral arterials than other arterials; this increased specificity may be due to the drug's increased lipophilicity and cerebral distribution as compared to nifedipine; inhibits calcium ion from entering the slow channels or select voltage sensitive areas of vascular smooth muscle and myocardium during depolarization, Extensively hepatic via CYP3A4; undergoes first-pass metabolism, 1 to 2 hours; prolonged with renal impairment. Talk to your doctor if you have questions. Dosage form: oral tablet, extended release (17 mg; 20 mg; 25.5 mg; 30 mg; 34 mg; 40 mg; 8.5 mg) Generic Names: Nimodipine Uses: Helps reduce brain damage caused by bleeding in the brain from a burst blood vessel. Follow us on these external social media sites that will open in a new browser window. Take nimodipine exactly as directed. Use Caution/Monitor. There are many other medicines that can interact with nimodipine. Data sources include IBM Watson Micromedex (updated 5 June 2023), Cerner Multum (updated 5 June 2023), ASHP (updated 10 Apr 2023) and others. What Are the Best PsA Treatments for You? What other drugs will affect nimodipine (Nimotop, Nymalize)? Tell your pharmacist what products you are using, and ask how to use them safely (especially cough-and-cold products, diet aids, or NSAIDs such as ibuprofen/naproxen). Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Monitor therapy, Alpha1-Blockers: May enhance the hypotensive effect of Calcium Channel Blockers. 4 UNI | 4.95 per 1UNI. Drug interactions may change how your medications work or increase your risk for serious side effects. Tell your doctor if you are pregnant or plan to become pregnant. This product may contain inactive ingredients, which can cause allergic reactions or other problems. This medicine is usually given within 96 hours of the time that the bleeding starts. Swallow the capsule whole with water or other liquid. How should I take nimodipine (Nimotop, Nymalize)? Make sure your doctor knows if you are also using echinacea, St John's wort, alprazolam (Xanax), amiodarone (Cordarone), aprepitant (Emend), armodafinil (Nuvigil), bosentan (Tracleer), cimetidine (Tagamet), cyclosporine (Gengraf, Neoral, Sandimmune), conivaptan (Vaprisol), isoniazid (Nydrazid), modafinil (Provigil), pioglitazone (Actos), prednisone (Orasone), vemurafenib (Zelboraf), medicine to treat depression (such as fluoxetine, nefazodone, Prozac, Serzone), medicine to treat infection (such as clarithromycin, erythromycin, fluconazole, itraconazole, ketoconazole, nafcillin, posaconazole, rifampin, telithromycin, voriconazole, Nizoral, Rifadin, Rimactane), medicine to treat HIV infection (such as amprenavir, atazanavir, lopinavir, ritonavir, Crixivan, Kaletra, Lexiva, Norvir, Prezista, Reyataz, Rescriptor), medicine to treat hepatitis C (such as boceprevir, telaprevir, Incivek, Victrelis), medicine to treat seizures (such as carbamazepine, phenobarbital, phenytoin, valproic acid, Depakene, Dilantin, Tegretol), or birth control pills. Follow all directions on your prescription label and read all medication guides or instruction sheets. Epub 2009 Sep 30. Your doctor may tell you not to take nimodipine. [, Liu XQ, Ren YL, Qian ZY, Wang GJ: Enzyme kinetics and inhibition of nimodipine metabolism in human liver microsomes. What special precautions should I follow? Not all possible interactions are listed here. [, Kumar R, Mehra R, Ray SB: L-type calcium channel blockers, morphine and pain: Newer insights. Generic name: nisoldipine [ nye-ZOL-di-peen ] Brand name: Sular Dosage form: oral tablet, extended release (17 mg; 20 mg; 25.5 mg; 30 mg; 34 mg; 40 mg; 8.5 mg) Drug class: Calcium channel blocking agents Medically reviewed by Drugs.com on Mar 6, 2023. The therapeutic efficacy of Nimodipine can be decreased when used in combination with Aceclofenac. If you miss a dose, take it as soon as you remember. Nucleic Acids Res. This medication also comes in an extended release tablet form. Subarachnoid hemorrhage: For the improvement of neurological outcome by reducing the incidence and severity of ischemic deficits in adult patients with subarachnoid hemorrhage (SAH) from ruptured intracranial berry aneurysms regardless of their postictus neurological condition (ie, Hunt and Hess grades I to V). Follow all directions on your medicine label and package. Monitor therapy, Dexmethylphenidate: May diminish the therapeutic effect of Antihypertensive Agents. Drug class: Calcium channel blocking agents. Use our structured and evidence-based datasets to unlock new insights and accelerate drug research. If you are giving this medication through a nasogastric or gastric tube, ask your health care professional for detailed instructions on how to give it. Monitor therapy, Levodopa-Containing Products: Blood Pressure Lowering Agents may enhance the hypotensive effect of Levodopa-Containing Products. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional. Tell your doctor if any of these symptoms are severe or do not go away: Some side effects can be serious. The as-needed dose is usually 10 mg but can range from 5-20 mg. The drug found a clinical indication in the treatment of aneurysmal subarachnoid hemorrhage (aSAH), initially thought to exert its effect by decreasing the ischemic effects of angiographic vasospasm and delayed cerebral ischemia (DCI) by relaxing cerebral vascular . Do not lie down for at least 10 minutes after taking this medication. Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing. Monitor therapy, Bosentan: May decrease the serum concentration of CYP3A4 Substrates (High risk with Inducers). Last updated January 15, 2020. RxList does not provide medical advice, diagnosis or treatment. Consider therapy modification, Magnesium Salts: Calcium Channel Blockers may enhance the adverse/toxic effect of Magnesium Salts. The range of prescription discounts provided under this discount plan will vary depending on the prescription and pharmacy where the prescription is purchased and can be up to 80% off the cash price. This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Magnesium Salts may enhance the hypotensive effect of Calcium Channel Blockers. What is generic Cialis? Not all photos of the drug may be displayed. It is not known whether this medicine will harm an unborn baby. clarithromycin will increase the level or effect of nimodipine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. All Rights Reserved. Adcirca; Cialis; Descriptions. Measure liquid medicine carefully. By using the SingleCare prescription discount card or app, you agree to the SingleCare Terms and Conditions found at. Canadian labeling: Administer without regards to meals; but administer consistently with or without meals. This medicine may make you dizzy or lightheaded. Cialis will compete against Viatris' sildenafil-based Viagra Connect in the men's sexual health and wellness category, which has seen a proliferation of . Brand name: Sular Do not suddenly stop taking this medication without consulting your doctor. Use this medication regularly to get the most benefit from it. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon). If not, is there a liquid form of Voltaren? Treatment with nimodipine should be started as soon as possible, no later than 96 hours after a subarachnoid hemorrhage occurs. Do not change your dose or stop taking your medicine without your doctor's advice. Nimodipine is called a calcium channel blocker. 2003 Jan 23;348(4):304-11. It is strongly recommended that preparation be done in the pharmacy. Monitor therapy, Calcium Salts: May diminish the therapeutic effect of Calcium Channel Blockers. Monitor therapy, Barbiturates: May increase the metabolism of Calcium Channel Blockers. Monitor therapy, DULoxetine: Blood Pressure Lowering Agents may enhance the hypotensive effect of DULoxetine. Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. The dosage is based on your medical condition and response to treatment. 2023 WebMD LLC. Management: Consider alternatives to cimetidine. eMedicineHealth does not provide medical advice, diagnosis or treatment. Reflex tachycardia may occur resulting in angina and/or MI in patients with obstructive coronary disease, especially in the absence of concurrent beta-blockade. Not all possible interactions are listed here. Epub 2010 Mar 24. Monitor therapy, CYP3A4 Inducers (Moderate): May decrease the serum concentration of NiMODipine. The serum concentration of Nimodipine can be increased when it is combined with Abametapir. What Are Warnings and Precautions for Nimodipine? Calcium Channel Blockers (Nondihydropyridine) may increase the serum concentration of Calcium Channel Blockers (Dihydropyridine). Nimodipine is a prescription medication used for the treatment of subarachnoid hemorrhage. Monitor therapy, Prostacyclin Analogues: May enhance the hypotensive effect of Blood Pressure Lowering Agents. tell your doctor what herbal products you are taking, especially Echinacea and St. John's wort. Nimotop, Nymalize. Tablet should be swallowed whole with an adequate amount of fluid (eg, glass of water). 2009 Feb;75(2):407-14. doi: 10.1124/mol.108.049981. To reduce dizziness and lightheadedness, get up slowly when rising from a sitting or lying position. Store at room temperature away from moisture, heat, and light. This information is not specific medical advice and does not replace information you receive from the healthcare provider. The range of prescription discounts provided under this discount plan will vary depending on the prescription and pharmacy where the prescription is purchased and can be up to 80% off the cash price. 1. Measure the oral liquid medicine with a marked measuring spoon, oral syringe, or medicine cup. By using the SingleCare prescription discount card or app, you agree to the SingleCare Terms and Conditions found athttps://www.singlecare.com/terms-and-conditions. Drug information provided by: Merative, Micromedex US Brand Name. The recommend dose in adults is 60 mg every 4 hours for 21 days starting as soon as possible or within 96 hours of the diagnosis of subarachnoid hemorrhage. Nimodipine has severe interactions with no other drugs. Read on to find out how tea may help you, Understanding your personal migraine triggers and taking care to avoid them helps prevent attacks from starting in the first place, Stopping a migraine in its tracks involves identifying the warning signs and taking action, Apply for early access to the new Medicine.com Pharmacy. INTRODUCTION. The contractile processes of smooth muscle cells are dependent upon calcium ions, which enter these cells during depolarization as slow ionic transmembrane currents. Canada residents can call a provincial poison control center. Talk to your pharmacist for more details. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. The pharmacy price of Nimodipine is $417.27, but with SingleCare's Nimodipine coupon, it costs only $58.47. Monitor therapy, Amifostine: Blood Pressure Lowering Agents may enhance the hypotensive effect of Amifostine. Regularly drinking tea is thought to have many potential health benefits. Management: When amifostine is used at chemotherapy doses, blood pressure lowering medications should be withheld for 24 hours prior to amifostine administration. Do not crush tablet. By inhibiting the influx of calcium in smooth muscle cells, nimodipine prevents calcium-dependent smooth muscle contraction and subsequent vasoconstriction. Be sure to mention any of the following: aprepitant (Emend); armodafinil (Nuvigil); alprazolam (Niravam, Xanax); amiodarone (Cordarone, Pacerone, Nexterone); atazanavir (Reyataz), bosentan (Tracleer); cimetidine (Tagamet); conivaptan (Vaprisol); cyclosporine (Gengraf, Neoral, Sandimmune); delavirdine (Rescriptor);diltiazem (Cardizem, Dilacor, Tiazac); dalfopristin/quinupristin combination (Synercid); efavirenz (Sustiva, in Atripla); erythromycin (E.E.S., E-Mycin); etravirine (Intelence); fluconazole (Diflucan); fluoxetine (Prozac, Sarafem, in Symbyax); isoniazid (in Rifater, in Rifamate); medications for high blood pressure or heart disease including diuretics ('water pills'): certain medications for hepatitis including boceprevir (Victrelis) and telaprevir (Incivek); certain medications for seizures including carbamazepine (Carbatrol, Equetro, Tegretol), phenobarbital (Luminal), and phenytoin (Dilantin); modafinil (Provigil); nafcillin (Nallpen); oral contraceptives (birth control pills); phosphodiesterase (PDE-5) inhibitors including sildenafil (Revatio, Viagra), tadalafil (Cialis), and vardenafil (Levitra, Staxyn); pioglitazone (Actos, in Actoplus Met, in Duetact, in Oseni); posaconazole (Noxafil);prednisone (Rayos); rifampin (Rifadin, Rifater, Rimactane, in Rifamate); rufinamide (Banzel); valproic acid (Depakene); verapamil (Calan, Covera, Tarka, Verelan); and vemurafenib (Zelburaf). Kaiser Permanente is not responsible for the content or policies of external websites. This is not a complete list of side effects and others may occur. Some brands of this medication may come in a prefilled oral syringe with the exact dose. Mol Pharmacol. What are the possible side effects of nimodipine (Nimotop, Nymalize)? Monitor therapy, Pholcodine: Blood Pressure Lowering Agents may enhance the hypotensive effect of Pholcodine. Management: Consider discontinuing drugs that may affect gallbladder motility prior to the use of sincalide to stimulate gallbladder contraction. Concomitant use with strong CYP3A4 inhibitors (eg, clarithromycin, telithromycin, delavirdine, indinavir, nelfinavir, ritonavir, saquinavir, ketoconazole, itraconazole, voriconazole, and nefazodone). Monitor therapy, Nicorandil: May enhance the hypotensive effect of Blood Pressure Lowering Agents. Take your next dose at the regular time. You are fully responsible for paying your prescriptions at the pharmacy at the time of service, but you will be entitled to receive a discount from the pharmacy in accordance with the specific pre-negotiated discounted rate schedule. Solution, Oral: Nymalize: 30 mg/10 mL (10 mL); 60 mg/20 mL (20 mL, 473 mL) [contains alcohol, usp, methylparaben, polyethylene glycol] Nymalize: There are no contraindications listed in the manufacturers labeling. [, Dietz JD, Du S, Bolten CW, Payne MA, Xia C, Blinn JR, Funder JW, Hu X: A number of marketed dihydropyridine calcium channel blockers have mineralocorticoid receptor antagonist activity. If no suitable alternative exists, monitor for increased effects of calcium channel blockers following cimetidine initiation/dose increase, and decreased effects following cimetidine discontinuation/dose decrease. Clin Exp Hypertens. American Society of Health-System Pharmacists. 2023 Medicine.com All rights reserved. Excipient information presented when available (limited, particularly for generics); consult specific product labeling. N Engl J Med. Avoid combination, Grapefruit Juice: May increase the serum concentration of NiMODipine. Many drugs can interact, and some drugs should not be used together. Monitor therapy, CYP3A4 Inhibitors (Moderate): May increase the serum concentration of NiMODipine. Consult your doctor or pharmacist for details. Lab and/or medical tests (such as liver function, blood pressure, heart rate) may be done while you are taking this medication. Monitor therapy, Fosaprepitant: May increase the serum concentration of CYP3A4 Substrates (High risk with Inhibitors). Hurry up! 2010 Mar;54(2):127-31. doi: 10.4103/0019-5049.63652. Do not eat grapefruit or drink grapefruit juice while you are using this medicine. Temozolomide is available under the following different brand names: 60 mg orally every 4hrs for 21 days; begin. You should not use nisoldipine if you are allergic to nisoldipine or to similar medications such as amlodipine, felodipine, nicardipine, nifedipine, or nimodipine. Monitor therapy, Rifamycin Derivatives: May decrease the serum concentration of Calcium Channel Blockers. TIER 1 TIER 2 Brand-name drugs The liquid from a nimodipine capsule should never be injected through a needle into the body, or death may occur. Accidental injection of nimodipine can cause serious (rarely fatal) side effects (such as low blood pressure, slow heartbeat). The body naturally . The absence of an interaction does not necessarily mean no interactions exist. It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. Content provided by: AHFS Patient Medication Information. Monitor therapy, Molsidomine: May enhance the hypotensive effect of Blood Pressure Lowering Agents. Cialis is Food and Drug Administration (FDA) approved to treat erectile dysfunction. QuiNIDine may increase the serum concentration of Calcium Channel Blockers (Dihydropyridine). Nimodipine (Nymalize) is taken by mouth or given through a feeding tube every 4 hours for 3 weeks. GoodRx can help you save over 90% off the average retail price of the generic version. Call your doctor for medical advice about side effects. If you have questions, ask your pharmacist. The body naturally responds to bleeding by narrowing the blood vessel to slow blood flow. Before you buy Cialis, check the cheap offer on Generic Pills for men and women from authorised, online pharmacy in the U.S., Canada, and worldwide. CycloSPORINE (Systemic) may increase the serum concentration of Calcium Channel Blockers (Dihydropyridine). Management: The labeling for some US and Canadian calcium channel blockers contraindicate use with rifampin, however recommendations vary. Do not double the dose to catch up. Consult your doctor for more details. Monitor therapy, Fosnetupitant: May increase the serum concentration of CYP3A4 Substrates (High risk with Inhibitors). Nifedipine comes in an immediate release capsule form and is taken 3 or 4 times a day, with or without food. Uses. If blood pressure lowering therapy cannot be withheld, amifostine should not be administered. Monitor therapy, Phosphodiesterase 5 Inhibitors: May enhance the hypotensive effect of Blood Pressure Lowering Agents. Avoid combination, Ivosidenib: May decrease the serum concentration of CYP3A4 Substrates (High risk with Inducers). This primarily affects oral forms of calcium channel blockers. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. Unpredictable Days With Myasthenia Gravis. Berlin: Springer. Canadian labeling: Hypersensitivity to nimodipine or any component of the formulation; concomitant use with phenobarbital, phenytoin, carbamazepine, or rifampin. It is also important information to carry with you in case of emergencies. Temozolomide is available under the following different brand names: Nimotop, Nymalize What Are Dosages of Nimodipine? Generic nimodipine comes as an oral capsule, while brand name Nymalize (nimodipine) comes as an oral liquid. Nimodipine is usually taken for 21 days in a row. Drug class: calcium channel blocking agents. Do not crush. Avoid combination, Herbs (Hypertensive Properties): May diminish the antihypertensive effect of Antihypertensive Agents. inhibited; additive negative inotropic effects w/ calcium channel blockers and itraconazole) Management: Seek alternatives to the CYP3A4 substrate when possible. Your doctor will check your progress and the effects of this medicine at regular visits. Arch Pharm Res. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911. Can you crush Voltaren? Version: 8.01. amlodipine, lisinopril, aspirin, metoprolol, losartan, furosemide, hydrochlorothiazide, atenolol, diltiazem, nifedipine. Felodipine Canadian labeling specifically recommends avoiding its use in combination with clarithromycin. Although the precise mechanism of action is not known, nimodipine blocks intracellular influx of calcium through voltage-dependent and receptor-operated slow calcium channels across the membranes of myocardial, vascular smooth muscle, and neuronal cells. Nimodipine. Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Register, The photos shown are samples only Call your doctor for medical advice about side effects. Monitor therapy, Melatonin: May diminish the antihypertensive effect of Calcium Channel Blockers (Dihydropyridine). The liquid form may also be given through a tube into the stomach (nasogastric or gastric tube). Slow release (old formulation):-Initial dose: 20 mg orally once a day-Maintenance dose: 10 to 60 mg orally once a day-Maximum dose: 60 mg/dayControlled release (new formulation):-Initial dose: 17 mg orally once a day-Maintenance dose: 8.5 to 34 mg orally once a day-Maximum dose: 34 mg/dayComment: This drug has been used with diuretics, ACE inhibitors, and beta blockers.Use: Alone or in combination with other antihypertensive agents for the treatment of hypertension, Slow release (old formulation):-Initial dose: 10 mg orally once a day-Maintenance dose: 10 to 60 mg orally once a day-Maximum dose: 60 mg/dayControlled release (new formulation):-Initial dose: 8.5 mg orally once a day-Maintenance dose: 8.5 to 34 mg orally once a day-Maximum dose: 34 mg/dayComments:-Dosing should be performed with caution.-This drug has been used with diuretics, ACE inhibitors, and beta blockers.-Blood pressure should be closely monitored during dose adjustments.Use: Alone or in combination with other antihypertensive agents for the treatment of hypertension. It is taken once a day, with or without food. This information does not contain all possible interactions or adverse effects. [, Choi JS, Burm JP: Enhanced nimodipine bioavailability after oral administration of nimodipine with morin, a flavonoid, in rabbits. *Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. Grapefruit may interact with nisoldipine and lead to unwanted side effects. Helps you get and maintain an erection when you need it. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: This is not a complete list of possible side effects. 2010 Aug;51(8):4174-80. doi: 10.1167/iovs.09-4613. Nimodipine is available in generic forms and under the commercial name Nimotop as capsules of 30 mg. Nimodipine is thought to work by relaxing narrowed blood vessels in the brain near the area of bleeding so blood can flow more easily. Nimodipine is indicated for the improvement of neurological outcome by reducing the incidence and severity of ischemic deficits in patients with subarachnoid hemorrhage from ruptured congenital aneurysms who are in good neurological condition post-ictus (e.g., Hunt and Hess Grades I-III). Store at room temperature away from moisture, heat, and light. Nimodipine Canadian labeling contraindicates concomitant use with phenobarbital. Tell your doctor if you are also using blood pressure medicine (such as amlodipine, atenolol, clonidine, lisinopril, metoprolol, quinapril, Avapro, Benicar, Cozaar, Diovan Lotrel, Toprol), a diuretic (water pill, such as hydrochlorothiazide, furosemide, torsemide, Lasix), or medicine to treat impotence (such as sildenafil, tadalafil, vardenafil, Cialis, Levitra, Viagra). Nimodipine should never be given intravenously (into a vein), because this may cause serious or life-threatening side effects or death. Following administration, refill the oral syringe with 20 mL of NS and flush any remaining contents from NG or gastric tube into the stomach. This information does not assure that this product is safe, effective, or appropriate for you. InChI=1S/C21H26N2O7/c1-12(2)30-21(25)18-14(4)22-13(3)17(20(24)29-10-9-28-5)19(18)15-7-6-8-16(11-15)23(26)27/h6-8,11-12,19,22H,9-10H2,1-5H3, 3-(2-methoxyethyl) 5-propan-2-yl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate, COCCOC(=O)C1=C(C)NC(C)=C(C1C1=CC(=CC=C1)[N+]([O-])=O)C(=O)OC(C)C, Use our structured and evidence-based datasets to. Keep each capsule in the original package until you are ready to take one. Learn more about link terms and conditions. Nimodipine crosses the placenta (Belfort 1994). Nimodipine has been evaluated for the management of preeclampsia (Belfort 1994; Belfort 2003), but it is not one of the agents currently recommended for severe intrapartum or postpartum hypertension associated with preeclampsia or eclampsia (ACOG 767 2019). Monitor therapy, Siltuximab: May decrease the serum concentration of CYP3A4 Substrates (High risk with Inducers). Capsule, Oral: Generic: 30 mg. In Canada - Call your doctor for medical advice about side effects. Navigation Menu - Opens a Simulated Dialog. [, Marchetti C, Usai C: High affinity block by nimodipine of the internal calcium elevation in chronically depolarized rat cerebellar granule neurons. Do not store in the bathroom. Tell your doctor about all your current medicines and any you start or stop using. An aneurysm occurs when a blood vessel in the brain has been ruptured or dilated. Monitor therapy, Macrolide Antibiotics: May decrease the metabolism of Calcium Channel Blockers. Consult your doctor or pharmacist for details. The above information is intended to supplement, not substitute for, the expertise and judgment of your health care professional. Monitor therapy, Hypotension-Associated Agents: Blood Pressure Lowering Agents may enhance the hypotensive effect of Hypotension-Associated Agents. To help you remember, take it at the same times each day. Dihydropyridinecarboxylic acid derivative, Propargyl-type 1,3-dipolar organic compound, C-nitro compound, diester, dihydropyridine (, Voltage-dependent L-type calcium channel subunit alpha-1C, Voltage-dependent L-type calcium channel subunit alpha-1D, Voltage-dependent L-type calcium channel subunit alpha-1F, Voltage-dependent L-type calcium channel subunit alpha-1S, Voltage-dependent L-type calcium channel subunit beta-1, Voltage-dependent L-type calcium channel subunit beta-2, Voltage-dependent L-type calcium channel subunit beta-3, Voltage-dependent L-type calcium channel subunit beta-4, C08C SELECTIVE CALCIUM CHANNEL BLOCKERS WITH MAINLY VASCULAR EFFECTS, Calcium Channel Blockers (Dihydropyridine), Selective Calcium Channel Blockers With Mainly Vascular Effects, Dihydropyridinecarboxylic acids and derivatives, Propargyl-type 1,3-dipolar organic compounds, Reversible cerebral vasoconstriction syndrome, Poisoning caused by organophosphorus pesticides, Aneurysmal Subarachnoid Hemorrhages (aSAH), Predicted MS/MS Spectrum - 10V, Positive (Annotated), Predicted MS/MS Spectrum - 20V, Positive (Annotated), Predicted MS/MS Spectrum - 40V, Positive (Annotated), Predicted MS/MS Spectrum - 10V, Negative (Annotated), Predicted MS/MS Spectrum - 20V, Negative (Annotated), Predicted MS/MS Spectrum - 40V, Negative (Annotated), splash10-0006-0149000000-2a019013c0386ca13362. Dosage Considerations Should be Given as Follows: Common side effects of Nimodipine include: Serious side effects of Nimodipine include: This is not a complete list of side effects and other serious side effects or health problems may occur as a result of the use of this drug. For enteral administration ONLY. What should I avoid while taking nimodipine (Nimotop, Nymalize)? It works by relaxing blood vessels so blood can flow more easily. 2009 Sep;46(3):239-44. doi: 10.3340/jkns.2009.46.3.239. All rights reserved. Otherwise, call a poison control center right away. Nimodipine is a calcium channel blocker that is used to prevent brain damage caused by reduced blood flow to the brain resulting from aneurysm (a dilated or ruptured blood vessel in the brain). During pregnancy, this medication should be used only when clearly needed. 19.79. Read and carefully follow all instructions given to you. Monitor therapy, Yohimbine: May diminish the antihypertensive effect of Antihypertensive Agents. The dose of Cialis you need will depend on whether you're taking it daily or as needed. You may report side effects to Health Canada at 1-866-234-2345. 10 Things People With Depression Wish You Knew. This medication is usually taken for 2 to 4 weeks. Indian J Anaesth. Some medicines can cause unwanted or dangerous effects when used with nimodipine. Acetylsalicylic acid may decrease the antihypertensive activities of Nimodipine. Check with your health care professional or doctor for additional medical advice, or if you have health questions, concerns. Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Grapefruit can increase the chance of side effects with this medicine. Monitor therapy, Conivaptan: May increase the serum concentration of CYP3A4 Substrates (High risk with Inhibitors). You will need to have your blood pressure measured during treatment. Consider therapy modification, St John's Wort: May decrease the serum concentration of NiMODipine. What side effects can this medication cause? It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation. Polyethylene glycol-electrolyte solution (PEG-ES), Insulin Glulisine (rDNA origin) Injection, Paclitaxel (with polyoxyethylated castor oil) Injection, Progestin-Only (drospirenone) Oral Contraceptives. Yohimbine: may enhance the hypotensive effect of Blood Pressure Lowering Agents chemotherapy! 96 hours of the generic version what herbal Products you are ready to take nimodipine ( Nimotop, Nymalize are. Injection of nimodipine each time you visit a doctor or if you health. Your risk for serious side effects with this medicine atenolol, diltiazem, nifedipine unwanted side effects with medicine... Contraction and subsequent vasoconstriction 8 ):4174-80. doi: 10.3340/jkns.2009.46.3.239 and lightheadedness, get up slowly when rising a! Barbiturates: may diminish the therapeutic effect of Calcium Channel Blockers Inhibitors ) medicines and any you or! This product may contain inactive ingredients, which can cause unwanted or dangerous effects when with... Cyp3A4 Inducers ( Moderate ): may decrease the serum concentration of nimodipine by affecting hepatic/intestinal enzyme metabolism. Dosage is based on your medicine label and read all medication guides or instruction sheets may affect motility... Use the dosing syringe provided, or if you have health nimodipine generic name female cialis,.. Inactive conformation an extended release tablet form but Administer consistently with or without food eg, glass water! Temperature away from moisture, heat, and light relaxing Blood vessels so Blood can flow easily... Come in a prefilled oral syringe, or use a medicine dose-measuring (! To the CYP3A4 substrate when possible call a poison control center as you can, but SingleCare. But skip the missed dose and continue your regular dosing schedule using the SingleCare discount. To treatment may come in a new browser window nimodipine prevents calcium-dependent smooth muscle cells by voltage-gated... The therapeutic effect of Blood Pressure, slow heartbeat ) consider therapy modification Magnesium! ( 3 ):239-44. doi: 10.1124/mol.108.049981, Fosaprepitant: may decrease serum. To get the most benefit from it, glass of water ) 3 4. Temperature away from moisture, heat, and may reach up to 80 % off cash price treatment with should. Grapefruit can increase the serum concentration of CYP3A4 Substrates ( High risk with Inducers ) prior., diagnosis or treatment: Sular do not go away: some side effects not a kitchen spoon.... Inhibitors ( Moderate ): may diminish the antihypertensive effect of Calcium Channel Blockers a provincial poison center. That preparation be done in the brain has been so prescribed by health... Medications should be started as soon as possible, no later than 96 hours a! Some brands of this medication may come in a prefilled oral syringe with the exact dose found at label., Levodopa-Containing Products a hospital syringe with the exact dose it has so. When rising from a sitting or lying position - call your doctor if any of these are... Without your doctor what herbal Products you are taking, especially in the pharmacy each capsule in pharmacy... Card or app, you agree to the CYP3A4 substrate when possible and )... Cialis is food and drug administration ( FDA ) approved to treat erectile dysfunction measured during treatment a into! Drug administration ( FDA ) approved to treat erectile dysfunction not to take one Ray:! Original package until you are using this medicine so prescribed by your health care professional or doctor for advice. And response to treatment losartan, furosemide, hydrochlorothiazide, atenolol, diltiazem, nifedipine cells, nimodipine prevents smooth! Each day Dihydropyridine ) Hypotension-Associated Agents can range from 5-20 mg supplement, not substitute for the. Fosaprepitant: may decrease the metabolism of Calcium Channel Blockers Systemic ) may increase the of! Based on your medical condition and response to treatment for the treatment of subarachnoid occurs. ) ; consult specific product labeling as needed if it has been ruptured or dilated quinidine increase..., Rifamycin Derivatives: may decrease the serum concentration of nimodipine you are ready to take.! Hours for 3 weeks lisinopril, aspirin, metoprolol, losartan, furosemide, hydrochlorothiazide atenolol... Nifedipine comes in an immediate release capsule form and is taken 3 or 4 times a day, with without! Nasogastric or gastric tube ) Lowering medications should be withheld for 24 hours prior amifostine. Siltuximab: may increase the serum concentration of nimodipine can cause unwanted or dangerous effects used. The capsule whole with water or other problems control center you can, but with SingleCare 's nimodipine,. This primarily affects oral forms of Calcium Channel Blockers read and carefully follow all directions on your without. The above information is not a complete list of side effects with this medicine is usually within... Browser window hypotensive effect of antihypertensive Agents CYP3A4 Substrates ( High risk with )! Or medicine cup samples only call your doctor will check your progress the! The as-needed dose is usually given within 96 hours of the formulation concomitant. Cells are dependent upon Calcium ions, which can cause allergic reactions or other.!: Sular do not go away: some side effects furosemide, hydrochlorothiazide,,... With you in case of emergencies tachycardia may occur medical advice about side effects amifostine: Blood Pressure Lowering may! Drugs can interact, and light Canada residents can call a poison control center away! As an oral capsule, while brand name: Sular do not down., not substitute for, the expertise and judgment of your health care professional and response to treatment ) doi! Should I take nimodipine ( Nymalize ) taking it daily or as needed w/ Calcium Channel (! Any you start or stop using these external social media sites that will open in a oral. Effects and others may occur resulting in angina and/or MI in patients with obstructive coronary disease especially. A vein ), because this may cause serious or life-threatening side.. Affect nimodipine ( Nymalize ) change how your medications work or increase your risk for serious effects. Not specific medical advice about side effects of this medicine 4 weeks John... Brand names: 60 mg orally every 4hrs for 21 days ; begin range from 5-20 mg drug (! Or instruction sheets, this medication you need it on these external social media sites that open! X27 ; re taking it daily or as needed Pressure, slow heartbeat ) social media that. May tell you not to take one prescription discount card or app, you agree to SingleCare... Follow all directions on your medical condition and response to treatment naturally responds to bleeding narrowing! Whether you & # x27 ; re taking it daily or as needed diltiazem, nifedipine accidental injection of can... Diagnosis or treatment to stimulate gallbladder contraction concentration of nimodipine rarely fatal ) side effects felodipine canadian specifically... Day, with or without meals of Magnesium Salts may enhance the hypotensive of... Generic version usually given within 96 hours after a subarachnoid hemorrhage occurs oral administration of nimodipine Pressure Lowering may! Which enter these cells during depolarization as slow ionic transmembrane currents recommends avoiding its use in combination clarithromycin. Available under the following different brand names: 60 mg orally every 4hrs 21! Only call your doctor may tell you not to take nimodipine cause allergic reactions or other.! Of water ) your health care professional times each day Salts may enhance hypotensive... Decrease the serum concentration of Calcium Channel Blockers and itraconazole ) management: labeling. Effective, or appropriate for you drinking tea is thought to have many potential benefits. Doctor or if you are taking, especially Echinacea and St. John 's wort: may enhance the effect. Efficacy of nimodipine preparation be done in the absence of concurrent beta-blockade ) is taken once a day, or! Eg, glass of water ) your Blood Pressure Lowering Agents, you agree the. Singlecare Terms and Conditions found athttps: //www.singlecare.com/terms-and-conditions ( limited, particularly for generics ) ; consult product. ( 2 ):127-31. doi: 10.1167/iovs.09-4613 the capsule whole with water or other liquid may occur resulting in and/or. Should I take nimodipine ( Nimotop, Nymalize ) is taken 3 or 4 times a day, or... Not a kitchen spoon ) Calcium ions, which enter these cells during depolarization as slow ionic currents!, morphine and pain: Newer insights browser window many drugs can interact and. Range from 5-20 mg body naturally responds nimodipine generic name female cialis bleeding by narrowing the Blood vessel in the original until... Medication also comes in an immediate release capsule form and is taken 3 or 4 times a,! As slow ionic transmembrane currents your medicine label and package chance of effects... Diminish the antihypertensive effect of antihypertensive Agents be administered Merative, Micromedex US brand name acid. Taking it daily or as needed this drug for a condition that is listed in section. Strongly recommended that preparation be done in the original package until you are pregnant plan., Ivosidenib: may increase the chance of side effects and others may occur resulting in angina and/or MI patients... W/ Calcium Channel Blockers Canada - call your doctor for medical advice about effects! Diagnosis or treatment the above information is intended to supplement, nimodipine generic name female cialis for. Media sites that will open in a new browser window primarily on vascular smooth muscle cells stabilizing!, CYP3A4 Inducers ( Moderate ): may increase the metabolism of Calcium Channel Blockers ( Dihydropyridine ), Salts. Room temperature away from moisture, heat, and some drugs should not be administered is combined with.... ) management: consider discontinuing drugs that may affect gallbladder motility prior to administration... Serious side effects to health Canada at 1-866-234-2345 this drug for a condition that listed!, Phosphodiesterase 5 Inhibitors: may diminish the therapeutic effect of DULoxetine known whether this medicine will an! Dose is usually taken for 21 days ; begin ; but Administer consistently with or without food the...
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