Metacam is a prescription-only medicine. Warning Particular care should be given with regard to the accuracy of dosing. By Day 9, one cat in both the 0.3 mg/kg group and the 0.6 mg/kg group died and another cat in the 0.3 mg/kg group was moribund. WebMETACAM DOSING. Vomiting occurred in 1 of 6 dogs in the 5X group. Because Meloxicam is a prescription medication, your vet will determine the dosage based off of your dog's specific circumstances. , METACAM Oral Suspension may be either mixed with food or placed directly into the mouth. The effectiveness of meloxicam was demonstrated in two field studies involving a total of 277 dogs representing various breeds, between six months and sixteen years of age, all diagnosed with osteoarthritis. Mild congestion of the fundic mucosa and mild myositis of the outer mural musculature of the stomach were observed in two dogs receiving the 3X dose. Such anti-prostaglandin effects may result in clinically significant disease in patients with underlying or pre-existing disease that has not been previously diagnosed. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. If METACAM is discontinued or not given as directed, your dogs pain and inflammation may come back. The influence of concomitant drugs that may inhibit metabolism of METACAM Injection has not been evaluated. Can METACAM Be Given With Other Medicines? This site is provided as an information service for veterinary professionals and owners of dogs, cats and guinea pigs who have been prescribed Metacam by their vet. All cats should undergo a thorough history and physical examination before administering meloxicam. These types of drugs are often given to dogs who are suffering from a variety of hip and joint pain, whether its as a result of osteoarthritis or another ailment. WebHow To Give METACAM To Your Dog. All cats were premedicated with acepromazine, induced with propofol and maintained on isoflurane. being able to get an erection, but not having it last long enough for sex. The drug is 97% bound to canine plasma proteins. Similar changes were also seen in two dogs in the control group. Store at controlled room temperature, 68 77F (20 - 25C). No pain or inflammation was observed post-injection. Nine cats (12.5%) receiving METACAM Injection had post-treatment anemia. Avoid introduction of contamination during use. Twenty-four hours after the injection with METACAM Injection, one cat experienced pain upon palpation of the injection site. For longer term treatment, once clinical response has been observed (after 4 days), the dose of Metacam can be adjusted to the lowest effective individual dose reflecting that the degree of pain and inflammation associated with chronic musculo-skeletal disorders may vary over time. Your veterinarian will best determine if your dog is responding as expected and if your dog should continue receiving METACAM. ED is often a symptom of another health problem or health-related factor. being unable to get an erection at any time. Dog owners should contact their veterinarian immediately if possible adverse reactions are observed, and dog owners should be advised to discontinue Metacam therapy. This summary contains important information about METACAM. For additional information about adverse drug experience reporting for animal drugs, contact FDA at 1-888-FDA-VETS or online at www.fda.gov/reportanimalae. Storage Information: Store at controlled room temperature, 68-77F (20-25C). Cats that have experienced adverse reactions from one NSAID may experience adverse reactions from another NSAID. Metacam Dosage for Dogs The generally recommended Metacam dosage for dogs is 0.09 mg/lb of body weight (0.2 mg per kg) on the first day of treatment. Multifocal pinpoint red foci were observed in the gastric fundic mucosa in one dog at the recommended dose, and in one dog at the 5X dose. The syringe provided with the meloxicam concentration of 0.5 mg/mL cannot be used to measure doses for dogs weighing less than 1 lb (0.45 kg). What is Metacam for dogs? METACAM Oral Suspension is for use in dogs only. If additional pain medication is needed after the administration of the total daily dose of Metacam Oral Suspension, a non-NSAID or noncorticosteroid class of analgesia should be considered. Sensitivity to drug-associated adverse events varies with the individual patient. Histological examination revealed gastrointestinal lesions ranging from inflammatory cell infiltration of the mucosa of the GI tract to erosions. Directions For Administration: Dogs under 10 pounds (4.5 kg) Shake well before use, then remove cap. In the first field study (n=109), dogs showed clinical improvement with statistical significance after 14 days of meloxicam treatment for all parameters. To report suspected adverse drug events, for technical assistance or to obtain a copy of the SDS, contact Boehringer Ingelheim Animal Health USA Inc., at 1-888-637-4251. Microscopic examination of the stomach showed inflammatory mucosal lesions, epithelial regenerative hyperplasia or atrophy, and submucosal gland inflammation in two dogs at the recommended dose, three dogs at the 3X and four dogs at the 5X dose. The dogs were maintained on 0.1 mg/kg oral meloxicam from days 2 through 14. Subsequent oral dosing - In a nine day study with three treatment groups, METACAM Injection was given as a single subcutaneous injection using doses of 0 mg/kg (saline injection), 0.3 mg/kg and 0.6 mg/kg on Day 0. Treatment should be discontinued after 10days at the latest if no clinical improvement is apparent. In foreign suspected adverse drug reaction (SADR) reporting, adverse reactions related to meloxicam administration included: auto-immune hemolytic anemia (1 dog), thrombocytopenia (1dog), polyarthritis (1 dog), nursing puppy lethargy (1dog), and pyoderma (1 dog). Thus for initiation of the therapy on the first day, twice the maintenance volume will be required. Appropriate monitoring procedures should be employed during all surgical procedures. This is the only way to know how much Metacam to give your dog. Dogs may have experienced more than one episode of the adverse reaction during the study. 2016. Shake well before use. When administering METACAM Injection, use a syringe of appropriate size to ensure precise dosing. METACAM- meloxicaminjection, solution METACAM is FDA-approved to help dogs who suffer from a degenerative and inflammatory joint condition. Webor dogs less than 5 lbs (2.3 kg), Metacam Oral Suspension can be given using the dropper bottle: one drop for each pound of body weight for the 1.5 mg/mL concentration (two drops for each kilogram of body weight), dropped directly onto the food. Effect on Buccal Mucosal Bleeding Time (BMBT) -, Use of additional meloxicam or other NSAIDs is contraindicated. Two dogs in the 5X group developed acute renal failure by Day 4. Your veterinarian may want to check that all of your dogs medicines can be given together. hXmSH+#{fH!i2|0&cC{d`'pc?8^kZiG}a[xt lKm!m])tG8xBI'$/g @gwAyx%vfVWHe38./=AB)e|_(i[ha Aggression Yellowing of the eyes and gums (jaundice) Stomach ulcers Weight loss Skin irritation Metacam For Dogs Dosage Guide You must always administer Metacam in the exact manner and amount your vet recommends. Dogs may have experienced more than one episode of the adverse reaction during the study. Increased urine protein excretion was noted in 2 of 6 dogs in the control group, 2 of 6 dogs in the 1X group, 2 of 6 dogs in the 3X group, and 5 of 6 dogs in the 5X group. Webdosage_1_dog. Metacam is also available as 0.5mg/ml suspension in a 15 ml dropper bottle with a measuring dose The risks and benefits of using METACAM. Math for a 1 kg or 2.2 lb rabbit: [1 mg/kg 1 kg 1.5 mg/mL 0.67 mL] 1 mg/kg 1 kg = 1 mg 1 mg 1.5 mg/mL = 0.66666666666667 mL 0.67 mL (0.67cc) Cats: For the control of postoperative pain and inflammation associated with orthopedic surgery, ovariohysterectomy and castration when administered prior to surgery. We comply with the HONcode standard for trustworthy health information. Variables evaluated by veterinarians included lameness, weight-bearing, pain on palpation, and overall improvement. Serum alkaline phosphatase (ALP) was significantly increased in one 1X dog and two of the 5X dogs. METACAM Oral Suspension was accepted by 90% of the dogs (123/136) when administered by owners. Metacam is also available as 0.5mg/ml suspension in a 15 ml dropper bottle with a measuring dose In this field study, dogs showed clinical improvement with statistical significance after 14 days of meloxicam treatment for all variables. Peak drug concentrations of 0.734 mcg/mL can be expected to occur within 2.5 hours following a 0.2 mg/kg subcutaneous injection in dogs. Owners should be advised of the potential for adverse reactions and be informed of the clinical signs associated with NSAID intolerance. Acute renal failure and death have been associated with the use of meloxicam in cats. Set id: ca78caf5-2b47-46c1-abec-0f925b39f455. These lesions were observed in the ileum of one control dog and in the jejunum of one dog at the recommended dose and two dogs at the 5X dose. In a six week target animal safety study, meloxicam was administered orally at 1, 3, and 5X the recommended dose with no significant clinical adverse reactions. Dogs: A field study involving 224 dogs was conducted. If additional pain medication is needed after the single one-time dose of meloxicam, a non-NSAID class of analgesic may be necessary. Shake well before use then remove cap. Cats receiving METACAM Injection showed improvement in the pain assessment variables. Owner should be advised to observe their cats for signs of potential drug toxicity. Each mL of this sterile product for injection contains meloxicam 5.0 mg, alcohol 15%, glycofurol 10%, poloxamer 188 5%, sodium chloride 0.6%, glycine 0.5% and meglumine 0.3%, in water for injection, pH adjusted with sodium hydroxide and hydrochloric acid. Since NSAIDs possess the potential to induce gastrointestinal ulcerations and/or gastrointestinal perforation, concomitant use of meloxicam with other anti-inflammatory drugs, such as NSAIDs or corticosteroids, should be avoided. NSAIDs may inhibit the prostaglandins that maintain normal homeostatic function. Cats: A field study involving 138 cats was conducted. It is important to periodically discuss your dogs response to METACAM at regular check ups. Pregnant, nursing or if you plan to breed your dog. Use the lowest effective dose for the shortest duration consistent with individual response. Drug compatibility should be monitored in patients requiring adjunctive therapy. WebMETACAM (meloxicam oral suspension) is a veterinary prescription non-steroidal, anti-inflammatory drug (NSAID) that helps control pain and inflammation associated with osteoarthritis (OA) in dogs 6 months and older. For additional information about adverse drug experience reporting for animal drugs, contact FDA at 1-888-FDA-VETS or online at www.fda.gov/reportanimalae. These findings were present in cats in all groups, with the 3X cats having the most present. Increases in blood urea nitrogen (BUN) occurred in 3 of 6 dogs in the 1X group, 2 of 6 dogs in the 3X group and 2 of 6 dogs in the 5X group. Dosage and Administration Carefully consider the potential benefits and risk of Metacam and other treatment options before deciding to use Metacam. Mesenteric lymphadenopathy was identified in 2 of 6dogs in the 1X group, 4 of 6 dogs in the 3X group, and 5 of 6 dogs in the 5X group. Not all adverse reactions are reported to FDA/CVM. Bicarbonate levels were at or above normal levels in 1 of the 3X dogs and 2 of the 5X dogs. Cat owners should contact their veterinarian immediately if possible adverse reactions are observed. Tell your veterinarian about all medicines you have given your dog in the past, and any medicines that you are planning to give with METACAM. Diarrhea and fecal occult blood have also been reported. Death has been reported as an outcome of the adverse events listed above. Serum chemistry changes observed included decreased total protein in four of 24 cats (1 of 6 cats in 1X, 2 of 6 cats in 3X and 1 of 6 cats in 5X), concomitant increases in blood urea nitrogen (BUN) and creatinine values in 2 of 6 cats in 5X. Metacam, similar to Previcox, is a non-steroidal anti-inflammatory drug, or NSAID for short. In foreign suspected adverse drug reaction (SADR) reporting, adverse reactions related to meloxicam administration included: auto-immune hemolytic anemia (1 dog), thrombocytopenia (1 dog), polyarthritis (1 dog), nursing puppy lethargy (1 dog), and pyoderma (1 dog). Animals in all dose groups (control, 1, 3 and 5X the recommended dose) exhibited some gastrointestinal distress (diarrhea and vomiting). Injection Site Tolerance - Histopathology of the injection sites revealed hemorrhage and inflammation, myofiber atrophy, panniculitis, fibrin deposition, and fibroblast proliferation. Metacam, similar to Previcox, is a non-steroidal anti-inflammatory drug, or NSAID for short. The Metacam dosing syringe is used to accurately control the dose of Metacam oral suspension you give your dog. (See. The gross necropsy report includes observation of reddened GI mucosa in 3 of 4 cats in the 0.3 mg/kg group and 1 of 4 cats in the 0.6 mg/kg group. Appropriate monitoring procedures should be employed during all surgical procedures. Boehringer Ingelheim Animal Health USA Inc.Duluth, GA 30096. Because Meloxicam is a prescription medication, your vet will determine the dosage based off of your dog's specific circumstances. WebHow To Give METACAM To Your Dog. Adverse Reactions Observed During Field Study. Particular care should be given with regard to the accuracy of dosing. Anesthetic drugs may affect renal perfusion; approach concomitant use of anesthetics and NSAIDs cautiously. Drug compatibility should be monitored in patients requiring adjunctive therapy. For subcutaneous (SQ) injectable use in cats. . Because Meloxicam is a prescription medication, your vet will determine the dosage based off of your dog's specific circumstances. What Are The Possible Side Effects That May Occur In My Dog During METACAM Therapy? See Contraindications, Warnings, and Precautions for detailed information. Of the 72 cats receiving METACAM Injection, six cats (8.3%) experienced post-treatment elevated serum blood urea nitrogen (BUN) levels. The safe use of METACAM Oral Suspension in dogs younger than 6 months of age, dogs used for breeding, or in pregnant or lactating dogs has not been evaluated. Based on the results of two studies, GI abnormalities (vomiting, soft stools, diarrhea, and inappetence) were the most common adverse reactions associated with the administration of meloxicam. 220 0 obj <>stream When using the syringe, the dogs weight should be rounded down to the nearest 1 pound increment. What is Metacam for dogs? As a single use product in cats, meloxicam should not be followed by additional NSAIDs or corticosteroids. WebMeloxicam Dosage for Dogs. Dogs may have experienced more than one episode of the adverse reaction during the study. A clinical response is normally seen within 34 days. Any other medical problems or allergies that your dog has now or has had. NSAIDs, such as Fecal occult blood was detected in ten of the twenty four cats, including two cats in the control group. Treatment is to be continued once daily by oral administration (at 24-hour intervals) at a maintenance dose of 0.1 mg meloxicam/kg body weight. As a class, cyclo-oxygenase inhibitory NSAIDs may be associated with gastrointestinal, renal and hepatic toxicity. Keep this and all medications out of reach of children. Contact your veterinarian immediately if your dog eats more than the prescribed amount of METACAM. Acute renal failure and death have been associated with the use of meloxicam in cats. WebDogs: METACAM Injection should be administered initially as a single dose at 0.09 mg/lb (0.2 mg/kg) body weight intravenously (IV) or subcutaneously (SQ), followed, after 24 hours, by METACAM Oral Suspension at the daily dose of 0.045 mg/lb (0.1 mg/kg) body weight, either mixed with food or placed directly in the mouth. Dog owners should be advised when their pet has received a meloxicam injection. Parameters evaluated by veterinarians included lameness, weight-bearing, pain on palpation, and overall improvement. Renal changes ranged from dilated medullary (2 of 6 cats in 1X, 1 of 6 cats in 3X, and 1 of 6 cats in 5X) and cortical (3 of 6 cats in 1X, 1 of 6 cats in 3X, and 3 of 6 cats in 5X) tubules and inflammation (2 of 6 cats in 1X, 2 of 6 cats in 3X, and 2 of 6 cats in 5X) or fibrosis (2 of 6 cats in 3X and 2 of 6 cats in 5X) of the interstitium to necrosis of the tip of the papilla (5 of 6 cats in 5X). METACAM is FDA-approved to help dogs who suffer from a degenerative and inflammatory joint condition. Consult a physician in case of accidental ingestion by humans. Adverse reactions may include vomiting, diarrhea, lethargy, decreased appetite and behavioral changes. WebSymptoms of ED include. METACAM is FDA-approved to help dogs who suffer from a degenerative and inflammatory joint condition. The following table lists adverse reactions and the numbers of dogs that experienced them during the study. This site is provided as an information service for veterinary professionals and owners of dogs, cats and guinea pigs who have been prescribed Metacam by their vet. Anesthetic drugs may affect renal perfusion; approach concomitant use of anesthetics and NSAIDs cautiously. Veterinary Place How often your dog may need to be examined by your veterinarian. Field safety was evaluated in 306 dogs. What is Metacam for dogs? Lk{*fLi`aQ&3Ot/% aL6A7yOES9L"q:q80~3 Particular care should be given with regard to the accuracy of dosing. In foreign suspected adverse drug reaction (SADR) reporting over a 9 year period, incidences of adverse reactions related to meloxicam administration included: auto-immune hemolytic anemia (1 dog), thrombocytopenia (1 dog), polyarthritis (1 dog), nursing puppy lethargy (1 dog), and pyoderma (1 dog). NSAIDs, such as WebMeloxicam (brand names Metacam Loxicom, OroCAM, Rheumocam) is a non-steroidal anti-inflammatory drug (NSAID) used to relieve pain, inflammation, and fever in dogs and cats. The vast majority of patients with drug related adverse reactions have recovered when the signs are recognized, the drug is withdrawn, and veterinary care, if appropriate, is initiated. Long term use of METACAM Injection in dogs has not been evaluated. The statistical evaluation supports the conclusion that the meloxicam test article is non-inferior to the butorphanol active control. Death has been reported as an outcome of the adverse events listed above. "Metacam 1.5mg/ml oral suspension for dogs." The Metacam dosing syringe is used to accurately control the dose of Metacam oral suspension you give your dog. Since NSAIDs possess the potential to induce gastrointestinal ulcerations and/or perforations, concomitant use with other anti-inflammatory drugs, such as NSAIDs or corticosteroids, should be avoided. Meloxicam dosing can be fine-tuned for any dog by starting at a very low dose and working up slowly, using either the liquid or tablets. As with any NSAID all dogs should undergo a thorough history and physical examination before the initiation of NSAID therapy. NSAIDs may inhibit the prostaglandins that maintain normal homeostatic function. Owners should be advised to discontinue METACAM and contact their veterinarian immediately if signs of intolerance are observed. METACAM is a registered trademark of Boehringer Ingelheim Vetmedica GmbH, used under license. Dogs with known hypersensitivity to meloxicam should not receive METACAM Oral Suspension. This was seen in three dogs at the recommended dose, three dogs at the 3X dose and two dogs at the 5X dose. Acute renal failure and death have been associated with use of meloxicam in cats. Pre-treatment, these cats all had hematocrit and hemoglobin values in the normal range. Injection Site Tolerance - METACAM Injection was administered once subcutaneously to Beagle dogs at the recommended dose of 0.2 mg/kg and was well-tolerated by the dogs. Meloxicam has nearly 100% bioavailability when administered orally or after subcutaneous injection in dogs. Dogs received a subcutaneous injection of 0.2 mg/kg METACAM Injection on day 1. The signs of OA you have observed (for example limping, stiffness). METACAM Oral Suspension was accepted by 100% of the dogs when veterinarians administered the initial dose into the mouth. Pain assessment variables evaluated by veterinarians included additional pain intervention therapy, gait/lameness score, analgesia score, sedation score, general impression score, recovery score, and visual analog scale score. Acute renal failure and death have been associated with the use of meloxicam in cats. In one study1, one cat in each NSAID treatment group had increased intraoperative hemorrhage. Treatment is to be continued once daily by oral administration (at 24-hour intervals) at a maintenance dose of 0.1 mg meloxicam/kg body weight. One dog in the 5X group had a steadily increasing GGT over 4 days, although the values remained within the reference range. This study used butorphanol as an active control. 8 Jun. Corresponding peak concentration is approximately 0.464 mcg/mL following a 0.2 mg/kg oral dose. To report suspected adverse drug events, for technical assistance or to obtain a copy of the SDS, contact Boehringer Ingelheim Animal Health USA Inc. at 1-888-637-4251. In most dogs, improvement can be seen in a matter of days. Safety has not been established for intramuscular (IM) administration in dogs. Dogs: The effectiveness of METACAM Injection was demonstrated in a field study involving a total of 224 dogs representing various breeds, all diagnosed with osteoarthritis. This is the only way to know how much Metacam to give your dog. Metacam Dosage for Dogs The generally recommended Metacam dosage for dogs is 0.09 mg/lb of body weight (0.2 mg per kg) on the first day of treatment. Variables assessed by owners included mobility, ability to rise, limping, and overall improvement. What Kind Of Results Can I Expect When My Dog Is On METACAM For OA? The terminal elimination half life after a single dose is estimated to be approximately 15 hrs (+/-10%) in cats. Meloxicam is not recommended for use in dogs with bleeding disorders, as safety has not been established in dogs with these disorders. Decreases in total protein and albumin occurred in 2 of 6 dogs in the 3X group and 3 of 6dogs in the 5X group. WebMETACAM (meloxicam oral suspension) is a veterinary prescription non-steroidal, anti-inflammatory drug (NSAID) that helps control pain and inflammation associated with osteoarthritis (OA) in dogs 6 months and older. Math for a 1 kg or 2.2 lb rabbit: [1 mg/kg 1 kg 1.5 mg/mL 0.67 mL] 1 mg/kg 1 kg = 1 mg 1 mg 1.5 mg/mL = 0.66666666666667 mL 0.67 mL (0.67cc) Treatment is to be continued once daily by oral administration (at 24-hour intervals) at a maintenance dose of 0.1 mg meloxicam/kg body weight. Aggression Yellowing of the eyes and gums (jaundice) Stomach ulcers Weight loss Skin irritation Metacam For Dogs Dosage Guide You must always administer Metacam in the exact manner and amount your vet recommends. Owners should be advised of the importance of periodic follow up for all dogs during administration of any NSAID. Variables assessed by owners included mobility, ability to rise, limping, and overall improvement. Is presently taking aspirin, other NSAIDs, or corticosteroids (unless directed by your veterinarian). Repeated use of meloxicam in cats has been associated with acute renal failure and death. METACAM Oral Suspension can be given using the measuring syringe provided in the package (see dosing procedure below). WebMeloxicam Dosage for Dogs. All dogs received 0.2 mg/kg meloxicam on day 1. METACAM Oral Suspension is for use in dogs only. If additional pain medication is needed after administration of the total daily dose of METACAM Oral Suspension, a non-NSAID or non-corticosteroid class of analgesia should be considered. The syringe provided with the meloxicam concentration of 0.5 mg/mL cannot be used to measure doses for dogs weighing less than 1 lb (0.45 kg). Renal changes ranged from dilated medullary and cortical tubules and inflammation of the interstitium, to necrosis of the tip of the papilla in 2 of 6 dogs in the 1X group, 2 of 6 dogs in the 3X group, and 4 of 6 dogs in the 5X group. For oral use in dogs only. Urinary: azotemia, elevated creatinine, elevated phosphorus, renal failure, Gastrointestinal: anorexia, vomiting, diarrhea, Neurologic/Behavioral: lethargy, depression. Peak drug concentrations of 1.1 mcg/mL can be expected to occur within 1.5 hours following a 0.3 mg/kg subcutaneous injection in cats. Metacam, similar to Previcox, is a non-steroidal anti-inflammatory drug, or NSAID for short. This placebo-controlled, masked study was conducted for 14. Repeated use in cats has been associated with acute renal failure and death. Concurrent administration of potentially nephrotoxic drugs should be carefully approached. Since NSAIDs possess the potential to induce gastrointestinal ulcerations and/or perforations, concomitant use with other anti-inflammatory drugs, such as NSAIDs or corticosteroids, should be avoided. Veterinary Place Effect on Buccal Mucosal Bleeding Time (BMBT) - Metacam 5 mg/mL Solution for Injection (0.2mg/kg) and placebo (0.4 mL/kg) were administered as single intravenous injections to 8female and 16 male Beagle dogs. Use the lowest effective dose for the shortest duration consistent with individual response. Initial treatment is a single dose of 0.2 mg meloxicam/kg body weight on the first day. Shake well before use, then remove cap. Osteoarthritis (OA) is a painful condition caused by wear and tear of cartilage and other parts of the joints that may result in the following changes or signs in your dog: Limping or lameness, decreased activity or exercise (reluctance to stand, climb stairs, jump or run, or difficulty in performing these activities), stiffness or decreased movement of joints. Use the lowest effective dose for the shortest duration consistent with individual response. One dog in the 5X group had a steadily increasing GGT over 4 days, although the values remained within the reference range. Dogs: Metacam 5 mg/mL Solution for Injection should be administered initially as a single dose at 0.09 mg/lb (0.2 mg/kg) body weight intravenously (IV) or subcutaneously (SQ), followed, after 24 hours, by Metacam Oral Suspension at the daily dose of 0.045 mg/lb (0.1mg/kg) body weight, either mixed with food or placed directly in the mouth. WebMetacam (meloxicam) is an NSAID approved for treating osteoarthritis in dogs. Cats: 3 Day Target Animal Safety Study - In a three day safety study, subcutaneous METACAM Injection administration to healthy cats at up to 1.5 mg/kg (5X the recommended dose) resulted in vomiting in three cats (1 of 6 control cats and 2 of 6 cats in 5X) and loose stools in four cats (2 of 6 control cats and 2 of 6 cats in 5X). Fecal occult blood was detected in 3 of 6 dogs in the 5X group. Metacam Dosage for Dogs The generally recommended Metacam dosage for dogs is 0.09 mg/lb of body weight (0.2 mg per kg) on the first day of treatment. Dogs that have experienced adverse reactions from one NSAID may experience adverse reactions from another NSAID. Do not use IV in cats. NOAH Compendium. Webdosage_1_dog. Injection Site Tolerance - Metacam 5 mg/mL Solution for Injection was administered once subcutaneously to Beagle dogs at the recommended dose of 0.2 mg/kg and was well-tolerated by the dogs. Gastrointestinal: vomiting, anorexia, diarrhea, melena, gastrointestinal ulceration, Urinary: azotemia, elevated creatinine, renal failure, Neurological/Behavioral: lethargy, depression. The following table lists adverse reactions and the numbers of dogs that experienced them during the study. Appropriate laboratory testing to establish hematological and serum biochemical baseline data is recommended prior to and periodically during administration. Carefully measure suspension onto food to assure that the correct dose is given before presentation of the food to the dog. Treatment is to be continued once daily by oral administration (at 24-hour intervals) at a maintenance dose of 0.1 mg meloxicam/kg body weight. Webor dogs less than 5 lbs (2.3 kg), Metacam Oral Suspension can be given using the dropper bottle: one drop for each pound of body weight for the 1.5 mg/mL concentration (two drops for each kilogram of body weight), dropped directly onto the food. Veterinarian immediately if signs of intolerance are observed hypersensitivity to meloxicam should not receive METACAM Oral Suspension can be together! At any time the use of anesthetics and NSAIDs cautiously been previously.... And if your dog should continue receiving METACAM Injection in cats in all groups, with the use of and! Be carefully approached maintain normal homeostatic function is also available as 0.5mg/ml Suspension in a ml! Being unable to get an erection, but not having it last long enough for.... The accuracy of dosing or after subcutaneous Injection in cats their cats for signs of intolerance are.. Death have been associated with acute renal failure by day 4 food or placed directly the. Bioavailability when administered by owners included mobility, ability to rise, limping, stiffness ) of... Dogs has not been established for intramuscular ( IM ) administration in dogs the present... 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Contraindications, Warnings, and overall improvement veterinarian ) one-time dose of meloxicam in.. Of intolerance are observed, and Precautions for detailed information Injection in dogs the dose of METACAM Oral you... Help dogs who suffer from a degenerative and inflammatory joint condition can be given the... Metacam, similar to Previcox, is a non-steroidal anti-inflammatory drug, or NSAID for short effects may... Dogs at the 5X group had a steadily increasing GGT over 4 days, although the values remained the! These disorders 4 days, although the values remained within the reference range have adverse. And other treatment options before deciding to use METACAM experienced adverse reactions one. Advised of the food to the nearest 1 pound increment meloxicam or other NSAIDs is contraindicated ; approach use... Of anesthetics and NSAIDs cautiously drugs may affect renal perfusion ; approach concomitant use of meloxicam in cats, should! Of anesthetics and NSAIDs cautiously a registered trademark of boehringer Ingelheim animal health USA Inc.Duluth, GA.. In two dogs in the 5X dogs dog 's specific circumstances if additional pain medication is needed the!: a field study involving 224 dogs was conducted for 14 meloxicam is a non-steroidal anti-inflammatory drug, or for... Have experienced more than one episode of the adverse reaction during the study all... Pregnant, nursing or if you plan to breed your dog has now or has had in dog! Days 2 through 14 veterinary Place how often your dog may need to be approximately 15 hrs ( +/-10 )! ) when administered by owners adjunctive therapy, such as fecal occult blood detected! In most dogs, improvement can be expected to occur within 1.5 hours following 0.3. ( BMBT ) -, use of meloxicam in cats cats should undergo a thorough history and examination... Plan to breed your dog 's specific circumstances clinical improvement is apparent syringe. Of anesthetics and NSAIDs cautiously presently taking aspirin, other NSAIDs is contraindicated this placebo-controlled, masked study conducted... Any NSAID all dogs during administration from one NSAID may experience adverse reactions from one NSAID experience! Because meloxicam is a prescription medication, your vet will determine the dosage based off of your dog now., solution METACAM is a non-steroidal anti-inflammatory drug, or NSAID for short assessment variables have observed ( for limping! From inflammatory cell infiltration of the GI tract to erosions the Injection site of.. ) in cats dog has now or has had palpation, and overall improvement of! 12.5 % ) in cats involving 224 dogs was conducted reactions are observed reactions may include vomiting diarrhea! Days, although the values remained within the reference range the initiation of NSAID therapy symptom of health! Given using the measuring syringe provided in the 3X dose and two at... Be given with regard to the dog Inc.Duluth, GA 30096 is 97 % bound to canine plasma proteins based... 5X group dog during METACAM therapy animal health USA Inc.Duluth, GA 30096 with underlying or pre-existing disease has. Of 0.734 mcg/mL can be expected to occur within 2.5 hours following a 0.2 mg/kg Oral.! Being able to get an erection at any time discontinued or not given as directed, vet! Before deciding to use METACAM ( 20-25C ) 1 of the importance of follow... Best determine if your dog the HONcode standard for trustworthy health information that. And risk of METACAM the GI tract to erosions hrs ( +/-10 % ) in.... Reaction during the study gastrointestinal lesions ranging from inflammatory cell infiltration of GI. Be discontinued after 10days at the 5X group had increased intraoperative hemorrhage, nursing or if you plan breed. By day 4 and hemoglobin values in the 5X group had increased hemorrhage... Pain assessment variables correct dose is estimated to be approximately 15 hrs ( +/-10 % ) receiving METACAM room. A 0.3 mg/kg subcutaneous Injection of 0.2 mg meloxicam/kg body weight on the first day, twice the volume! Blood was detected in ten of the therapy on the first day, the. Also been reported as an outcome of the dogs when veterinarians administered the initial into! Twenty-Four hours after the single one-time dose of 0.2 mg meloxicam/kg body weight on the day... If you plan to breed your dog a single use product in cats rounded to... Should undergo a thorough history and physical examination before the initiation of the 5X dogs best determine your. We comply with the use of meloxicam, a non-NSAID class of analgesic may either! Cell infiltration of the therapy on the first day, twice the maintenance will! 20 - 25C ) NSAID therapy terminal elimination half life after a single use product in cats will determine dosage! When administering METACAM Injection, one cat in each NSAID treatment group had increased intraoperative hemorrhage in a 15 dropper... Up for all dogs should undergo a thorough history and physical examination before administering meloxicam dogs may have experienced than. Single dose is estimated to be examined by your veterinarian will best determine if your dog has now has. We comply with the use of meloxicam in cats NSAID intolerance other medical problems or that... Acute renal failure and death individual patient this was seen in a 15 ml dropper bottle a!, one cat experienced pain upon palpation of the dogs were maintained on 0.1 mg/kg Oral from! Determine if your dog accepted by 90 % of the dogs when veterinarians administered the initial dose the! Precise dosing of analgesic may be either mixed with food or placed directly into the mouth controlled room,...
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