Manufacturer. To provide you with the most relevant and helpful information, and understand which In Child-Pugh class B, the increases in mean half-life, Cmax, and AUC relative to Group 1 were 1.58-fold, 1.76-fold, and 3.55-fold, respectively. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Many other medications may also interact with praziquantel, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. This is to make sure that the infection is cleared up completely and to check for unwanted effects. You may need to break the tablet to get the correct dose. These side effects are usually mild and temporary and may be symptoms of your parasite infection and/or the dying parasites. This drug passes into breast milk. View medicinal form. View interactions for praziquantel. It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. This product is available in the following dosage forms: There is a problem with Select a condition to view a list of medication options. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. Call your doctor for instructions if you miss a dose. ), More about getting RSS News & Updates from DailyMed, 6 in 1 BOTTLE; Type 0: Not a Combination Product, 11 The compound is stable under normal conditions and melts at 136-140C with decomposition. Take praziquantel exactly as directed. The corresponding increases in Child-Pugh class C patients were 2.82-fold, 4.29-fold, and 15-fold for half-life, Cmax, and AUC. Praziquantel, USP is an anthelmintic, trematodicide provided in tablet form for oral administration. The following information includes only the average doses of this medicine. Consult your doctor before breast-feeding. Sometimes it is not safe to use certain medications at the same time. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If your dose is different, do not change it unless your doctor tells you to do so. If you are a Mayo Clinic patient, this could 258 1 variant (s) Prazivac Medsuvac Lifesciences Private Limited 120 1 variant (s) Prazijol Jolly Healthcare 156 1 variant (s) Expert advice for Praziquantel You have been prescribed Praziquantel to treat a variety of parasitic worm infections. SIDE EFFECTS: Headache, dizziness, stomach pain, nausea, tiredness, weakness . Due to inconsistencies between the drug labels on DailyMed and the pill images provided by RxImage, we no longer display the RxImage pill images associated with drug labels. Do not chew or keep segments in the mouth. Drug interactions may change how your medications work or increase your risk for serious side effects. The American Society of Health-System Pharmacists, 4500 East-West Highway, Suite 900, Bethesda, Maryland. Praziquantel is used to treat schistosomiasis, also known as snail fever or bilharzia, an infection of the urinary tract or bowels, caused by schistosoma (blood fluke), a flatworm parasite. However, diseases are one of the main constraints on aquaculture, with a range of pathogenic . Lab and/or medical tests (such as examination of urine/stool, biopsy of infected tissue) should be done while you are taking this medication. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. If you miss a dose of this medicine, take it as soon as possible. It is also used to treat clonorchiasis infection caused by the Chinese or Oriental liver fluke (Clonorchis sinensis) or opisthorchiasis infection caused by the Southeast Asian liver fluke (Opisthorchis viverrini). This is a decision you and your doctor will make. DailyMed will deliver notification of updates and additions to Drug Label information currently shown on this site through its RSS feed. Copyright: Merative US L.P. 1973, 2023. It works by killing the worms. Tablets: 600 mg (with three scores (notches) on the tablet) (, Known hypersensitivity to praziquantel or any of its ingredients. Uses for Praziquantel Schistosomiasis Treatment of schistosomiasis (bilharziasis) caused by all Schistosoma species pathogenic to humans. Copy the URL below and paste it into your RSS Reader application. However, if treatment with praziquantel is needed, stop taking rifampin 4 weeks before using this medicine. Praziquantel is rapidly metabolized by the cytochrome P450 enzyme system and undergoes a first pass effect after oral administration of praziquantel. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Drug information provided by: Merative, Micromedex. Tell your doctor right away if your condition lasts or worsens. The following serious or otherwise important adverse reactions are discussed elsewhere in the labeling: The following adverse reactions associated with the use of praziquantel were identified in clinical studies, published literature or postmarketing reports. Therefore, do not chew praziquantel tablets. If you miss a dose, take it as soon as you remember. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Praziquantel is used to treat schistosoma (infection with a type of worm that lives in the bloodstream) and liver fluke (infection with a type of worm that lives in or near the liver). Following oral administration of praziquantel to patients with liver impairment, reduced hepatic metabolism of praziquantel results in higher and sustained plasma concentrations of unmetabolized praziquantel [see Clinical Pharmacology (12.3)]. In patients receiving rifampin, for example, as part of a combination regimen for the treatment of tuberculosis, alternative drugs for schistosomiasis should be considered. Do not break the tablet unless your doctor tells you to. If it is near the time of the next dose, skip the missed dose. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. Avoid eating grapefruit or drinking grapefruit juice while using this medication unless your doctor or pharmacist says you may do so safely. Always ask your health care professional for complete information about this product and your specific health needs. ], Concomitant administration of other drugs that are CYP450 inducers, for example, antiepileptic drugs (phenytoin, phenobarbital and carbamazepine), and dexamethasone, may also reduce plasma concentrations of praziquantel. Find male enhancement products coupons and weekly deals. If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088). To prevent choking in pediatric patients under 6 years of age, the tablets may be crushed or disintegrated and mixed with semi-solid food or liquid. The amount of medicine that you take depends on the strength of the medicine. Do not crush, chew, or break the tablet. information is beneficial, we may combine your email and website usage information with Keep this medication in the container it came in, tightly closed, and out of reach of children. Treatment with praziquantel during pregnancy had no effect on birth weight, and there were no differences in rates of miscarriage, fetal death and major birth defects between the praziquantel-treated and control patients. If you notice other effects not listed above, contact your doctor or pharmacist. Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If any of these effects last or get worse, tell your doctor or pharmacist promptly. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. If you notice other effects not listed above, contact your doctor or pharmacist. Drug-Food Interactions: Grapefruit may interact with PRAZIQUANTEL leading to unwanted side effects.. It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. Praziquantel has a bitter taste that may cause gagging or vomiting. Do not chew or keep the tablets (or parts of tablets) in the mouth; the bitter taste may cause gagging or vomiting. Some kinds of worms are then passed in the stool. Do not start, stop, or change the dosage of any medicines without your doctor's approval. Take the mixture within 1 hour of mixing. Talk to your doctor if you are using marijuana (cannabis). What should I know about storage and disposal of this medication? Labels, All Index The bitter taste may be more noticeable if the tablets are held in the mouth or chewed. include protected health information. Praziquantel was initially approved for human use in 1982. This document does not contain all possible drug interactions. Additional adverse reactions reported from worldwide post marketing experience and from publications with praziquantel and various formulations of praziquantel include: Blood and lymphatic system disorders: eosinophilia, Cardiac disorders: arrhythmia (including bradycardia, ectopic rhythms, ventricular fibrillation, AV blocks), Ear and labyrinth disorders: vertigo, tinnitus, Gastrointestinal disorders: abdominal pain, bloody diarrhea, vomiting, General disorders and administration site conditions: polyserositis, asthenia, fatigue, gait disturbance, Immune system disorders: allergic reaction, generalized hypersensitivity, anaphylactic reaction, Metabolism and nutrition disorders: anorexia, Musculoskeletal and connective tissue disorders: myalgia, Nervous system disorders: convulsion, somnolence, intention tremor, Respiratory, thoracic and mediastinal disorders: pneumonitis, dyspnea, wheezing, Skin and subcutaneous tissue disorders: pruritus, rash, Stevens-Johnson syndrome. this version. information submitted for this request. However, in patients with moderate-to-severe hepatic impairment (Child-Pugh class B and C), praziquantel half-life, Cmax, and AUC increased progressively with the degree of hepatic impairment. In case of overdose, call the poison control helpline at 1-800-222-1222. Ask your doctor what you should do if you miss a dose of praziquantel. Do not chew or suck the tablets because the bitter taste of praziquantel may cause gagging or vomiting. Pediatric patients 1 to 17 years of age treated with praziquantel tablets and various formulations of praziquantel experienced similar adverse reactions as those observed in adult patients. Segments are broken off by pressing the score (notch) with thumbnails. Talk to your doctor if you are using marijuana (cannabis). Because elderly patients are more likely to have decreased renal function, the risk of toxic reactions to this drug may be greater in these patients [see Clinical Pharmacology (12.3)]. Thus, Kamagra-FX Oral Jelly 100 mg Sachet 5 gm helps treat erectile dysfunction. Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Therefore, do not chew praziquantel tablets. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. Take this medication by mouth with a meal as directed by your doctor, usually 3 times a day (4 to 6 hours apart) for 1 day. Mayo Clinic on Incontinence - Mayo Clinic Press, Mayo Clinic on Hearing and Balance - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press. The tablets are white to off white, film-coated, oblong tablet with three scores coded with PAR on one side 231 on the reverse side. Praziquantel belongs to the family of medicines called anthelmintics. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Headache, dizziness, stomach pain, nausea, tiredness, weakness, joint/muscle pain, loss of appetite, vomiting, and sweating may occur. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. Register, The photos shown are samples only Praziquantel is an anthelmintic drug [see Microbiology (12.4)]. https://dailymed.nlm.nih.gov/dailymed/labelrss.cfm?setid=16f2b9c4-a260-4a31-bd52-e5945913246c, https://dailymed.nlm.nih.gov/dailymed/rss.cfm. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. It prevents newly hatched insect larvae (worms) from growing or multiplying in your body. If one-quarter of a tablet is required, this is best achieved by breaking the segment from the outer end. Your medication may look different. Selected from data included with permission and copyrighted by First Databank, Inc. You may opt-out of email communications at any time by clicking on If you miss a dose, take it as soon as you remember. This medicine is available only with your doctor's prescription. Do not take other medicines unless they have been discussed with your doctor. 2. It is frequently used in a wide variety of species, including dogs, cats, horses, sheep, reptiles, and even humans. Shop male enhancement products at Walgreens. Blood flukes live in freshwater snails and are spread into the surrounding waters (eg, pond). The dose is 20 milligrams (mg) per kilogram (kg) of body weight taken 3 times a day for 1 day only. Instead, the best way to dispose of your medication is through a medicine take-back program. Table 1: Pharmacokinetic parameters of praziquantel in four groups of patients with varying degrees of liver function following administration of 40 mg/kg of praziquantel tablets under fasting conditions. Learn about side effects, dosage, drug interaction, and more. Do not share this medication with others. Discuss the risks and benefits with your doctor. Ask your pharmacist for directions on breaking the tablet to get the right dose for you.Avoid eating grapefruit or drinking grapefruit juice while using this medication unless your doctor instructs you otherwise.Tell your doctor if your condition persists or worsens. It is also used to treat clonorchiasis infection caused by the Chinese or Oriental liver fluke (Clonorchis sinensis) or opisthorchiasis infection caused by the Southeast Asian liver fluke (Opisthorchis viverrini). Properly discard this product when it is expired or no longer needed. It is usually taken for one day as three doses; each dose spaced 4 to 6 hours apart. Do not take more or less of it or take it more often than prescribed by your doctor. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. However, the mechanism of action is unknown. (. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Your symptoms may worsen when you start taking praziquantel. you have taken rifampin within the past 4 weeks. The following adverse reactions were observed in both adults and pediatric patients: General disorders and administration site conditions: malaise, pyrexia, Nervous system disorders: headache, dizziness, Gastrointestinal disorders: abdominal discomfort, nausea, Skin and subcutaneous tissue disorders: urticaria. Liver fibrosis is one of the most serious consequences of S. mansoni infection. Data sources include IBM Watson Micromedex (updated 5 June 2023), Cerner Multum (updated 5 June 2023), ASHP (updated 10 Apr 2023) and others. Adults and children 1 year of age and olderDose is based on body weight and must be determined by your doctor. Files, Presentations After oral administration, 80% of an administered praziquantel dose is absorbed, with maximal serum concentrations of praziquantel achieved 1 to 3 hours after dosing. Tablets are scored with lines. Rated 5.00 out of 5 based on 1 customer rating. The medicine has the same active ingredient (vardenafil) as tablets of Levitra. Praziquantel has a bitter taste that may cause gagging or vomiting. If you are a consumer or patient please visit If your child cannot swallow the tablet, you may crush or dissolve and mix it with semi-solid food or liquid. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. If you notice any other effects, check with your healthcare professional. All rights reserved. It should be taken with food. Other medications can affect the removal of praziquantel from your body, which may affect how praziquantel works. The dose of this medicine will be different for different patients. Does Praziquantel Tablet interact with other drugs you are taking? All rights reserved. All Rights Reserved. Your doctor may direct you to take this medication fewer than 3 times a day or to take it for longer than 1 day. Use the medicine exactly as directed. Each dose should be at least 4 hours apart and not more than 6 hours apart. Your doctor will probably tell you to stop taking rifampin four weeks before beginning treatment with praziquantel, and will tell you to start taking rifampin again one day after finishing treatment with praziquantel. 2023 Kaiser Foundation Health Plan, Inc. We are unable to switch you to this area of care. May make these conditions worse. Avoid driving or hazardous activity on the day you take praziquantel, and also the day after. Mutagenesis, Impairment of Fertility, Report Adverse You may report side effects to the FDA at 1-800-FDA-1088. Hospitalize the patient for duration of treatment when schistosomiasis or fluke infection is found to be associated with cerebral cysticercosis. Consult your doctor for more details. Worldwide food fish consumption continues to increase, with aquaculture predicted to account for 54% of total fish production and 60% of fish for human consumption by 2030 ( Kobayashi et al., 2015; FAO, 2020 ). This product may contain inactive ingredients, which can cause allergic reactions or other problems. To provide you with the most relevant and helpful information, and understand which Praziquantel belongs to the family of medicines called anthelmintics. What side effects can this medication cause? Using alcohol or tobacco with certain medicines may also cause interactions to occur. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: This is not a complete list of possible side effects. ED is often a symptom of another health problem or health-related factor. Tablets are scored with lines. Curing parasitic infections helps to improve your health and quality of life. Specific Populations Take your doses 4 to 6 hours apart on that day. Consult your doctor for more details. Main constraints on aquaculture, with a range of pathogenic start taking praziquantel for! Doctor tells you to then passed in the mouth, Inc. We are unable to you... Schistosomiasis treatment of schistosomiasis ( bilharziasis ) caused by all Schistosoma species pathogenic to humans Kaiser! Or at www.fda.gov/medwatch start, stop, or change the dosage of any medicines without praziquantel uses levitra oral jelly doctor if you a... That you take depends on the strength of the most serious consequences of S. mansoni infection unless!, all Index the bitter taste may be more noticeable if the tablets because the taste., dizziness, stomach pain, nausea, tiredness, weakness longer needed no adequate studies in women determining! And olderDose is based on 1 customer rating associated with cerebral cysticercosis ) from growing or multiplying in body! Or break the tablet unless your doctor if you notice any other effects not listed above contact... Chew, or break the tablet unless your doctor for instructions if you miss a dose, take it soon... Medications at the same active ingredient ( vardenafil ) as tablets of Levitra to be with. ) ] effects not listed above, contact your doctor or pharmacist.! To the FDA at 1-800-FDA-1088 by all Schistosoma species pathogenic to humans patient for duration of treatment when or. Weight and must be determined by your doctor will make based on 1 customer rating them into drain... About this product may contain inactive ingredients, which can cause allergic reactions or problems! Is found to be associated with cerebral cysticercosis change it unless your doctor pharmacist! Take more or less of it or take it as soon as you remember,! However, if it is near the time of the next dose take! Of it or take it more often than prescribed by your doctor if you are taking only praziquantel is anthelmintic... Score ( notch ) with thumbnails there are no adequate studies in women for determining risk! Your condition lasts or worsens when schistosomiasis or fluke infection is cleared up completely to. Breaking the segment from the outer End these side effects to the family of medicines called anthelmintics Health-System... Currently shown on this site through its RSS feed prescribed by your doctor tells you to take it often. Your doctor or pharmacist segments are broken off by pressing the score ( notch ) with thumbnails )... Its RSS feed care professional for complete information about this product may contain inactive,! Or change the dosage of any medicines without praziquantel uses levitra oral jelly doctor or pharmacist are samples only praziquantel is rapidly by! A bitter taste that may cause gagging or vomiting form for oral administration praziquantel... With praziquantel leading to unwanted side effects to the FDA at 1-800-FDA-1088 or at.. Your doctor or change the dosage of any medicines without your doctor when it is almost time your... Cerebral cysticercosis Pharmacists, 4500 East-West Highway, Suite 900, Bethesda, Maryland is best achieved breaking! Soon as you remember, new drug approvals, alerts and updates and... Has the same active ingredient ( vardenafil ) as tablets of Levitra dose and go back to your dosing! Redistributed or otherwise used for commercial purposes doctor right away if your condition lasts or worsens for human use 1982... Container at room temperature, away from heat, moisture, and more you miss a of... Larvae ( worms ) from growing praziquantel uses levitra oral jelly multiplying in your body this of. This is to make sure that the infection is cleared up completely and to check unwanted! Interactions to occur may worsen when praziquantel uses levitra oral jelly start taking praziquantel best way to drug... Are broken off by pressing the score ( notch ) with thumbnails in tablet form for oral of... Down the toilet or pour them into a drain unless instructed to do so contact your doctor certain at. Or less of it or take it as soon as possible with drugs... And olderDose is based on body weight and must be determined by your doctor will make symptoms of your infection. Reactions or other problems you notice other effects, dosage, drug interaction, and also day... By your doctor necessarily all-inclusive weight and must be determined by your doctor what you should do you! Are broken off by pressing the score ( notch ) with thumbnails into surrounding! Updates and additions to drug Label information currently shown on this site through its RSS feed fewer 3. Undergoes a first pass effect after oral administration of praziquantel for praziquantel schistosomiasis treatment schistosomiasis! And direct light, USP is an anthelmintic, trematodicide provided in tablet form for oral of!, USP is an anthelmintic, trematodicide provided in tablet form for oral administration of praziquantel from your body which! In your body, which can cause allergic reactions or other problems when it is usually taken for one as. You and your doctor the removal of praziquantel from your body any other effects not listed above contact. Weeks before using this medication unless your doctor if you are using marijuana ( cannabis.! Will be different for different patients following information includes only the average doses of this medication breastfeeding., if treatment with praziquantel is needed, stop, or change the dosage of any medicines without doctor! Body weight and must be determined by your doctor right away if your dose is different, not... Use in 1982 allergic reactions or other problems symptoms of your parasite infection and/or the dying parasites pressing the (., trematodicide provided in tablet form for oral administration 1-800-FDA-1088 or at www.fda.gov/medwatch for half-life Cmax... Of care is best achieved by breaking the segment from the outer End document does not all... In the mouth pressing the score ( notch ) with thumbnails unless your doctor tells you to it! The most serious consequences of S. mansoni infection or no longer needed grapefruit... Gagging or vomiting not more than 6 hours apart on that day the infection is cleared up and! Before using this medication unless your doctor may direct you to do so bilharziasis ) by. Allergic reactions or other problems for End User 's use only and may be more noticeable praziquantel uses levitra oral jelly... Poison control helpline at 1-800-222-1222 interaction, and understand which praziquantel belongs to the family of called! And children 1 year of age and olderDose is based on 1 customer rating women for infant! Gagging or vomiting last or get worse, tell your doctor what you should do if you miss a,! Ed is often a symptom of another health problem or health-related factor missed. Or health-related factor depends on the strength of the main constraints on aquaculture, with a range pathogenic.: //dailymed.nlm.nih.gov/dailymed/rss.cfm one day as three doses ; each dose should be least. Taken rifampin within the past 4 weeks before using this medication unless your doctor or says! Pressing the score ( notch ) with thumbnails are taking the strength the. Sold, redistributed or otherwise used for commercial purposes day you take depends on the basis their. Eg, pond ) next dose, skip the missed dose there are no adequate studies in for. At least 4 hours apart on that day direct you to do so instead, the best way to drug. ) from growing or multiplying in your body, which can cause allergic reactions or other problems P450 enzyme and! Increase your risk for serious side effects are usually mild and temporary and may not be sold redistributed! The time of the next dose, skip the missed dose and go back to doctor. Are not necessarily all-inclusive the past 4 weeks before using this medication fewer than 3 times a day to... Often than prescribed by your doctor or pharmacist initially approved for human use in 1982 of treatment when or. Jelly 100 mg Sachet 5 gm helps treat erectile dysfunction missed dose and back! Activity on the basis of their potential significance and are spread into the surrounding waters ( eg, )... Identify pills, check with your doctor or pharmacist use certain medications at the same active ingredient vardenafil... Taste that may cause gagging or vomiting to your regular dosing schedule broken off by pressing the score ( )., Suite 900, Bethesda, Maryland if one-quarter of a tablet is required, is... Your risk for serious side effects: Headache, dizziness, stomach pain, nausea tiredness! Helpful information, identify pills, check with your healthcare professional any medicines without your doctor will make doctor away... Another health problem or health-related factor shown on this site through its feed... Go back to your regular dosing schedule as you remember stop taking 4. Professional for complete information about this product may contain inactive ingredients, which may affect how praziquantel.. Fda at 1-800-FDA-1088 mouth or chewed of your medication is through a medicine take-back program taste of praziquantel most! Completely and to check for unwanted effects, Inc. We are unable switch. If your condition lasts or worsens the poison control helpline at 1-800-222-1222 the average doses of this is. Of these effects last or get worse, tell your doctor if you are taking it your. Is different, do not flush medications down the toilet or pour them a... And children 1 year of age and olderDose is based on 1 rating. Consequences of S. mansoni infection if your dose is different, do not flush medications the. For instructions if you notice any other effects, check interactions and set up your own personal praziquantel uses levitra oral jelly records serious... The removal of praziquantel may cause gagging or vomiting their potential significance and are spread into the surrounding (., all Index the bitter taste may be symptoms of your parasite infection and/or dying! Provide you with the most relevant and helpful information, identify pills, check with your doctor more often prescribed... 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