A 25mg dose of intramuscular promethazine reaches a C max of 22ng/mL. Dispense it in an opaque ointment jar, an ointment tube, or light-resistant unit-dose syringes. Promethazine oral tablet is used to treat several conditions, such as allergies, motion sickness, nausea and vomiting. You should not take it if you have bone marrow disease or you take other drugs that affect the ability of your bone marrow to make blood cells. Special care should be taken when using this medication in children who have lost a lot of fluid (dehydration), those who have a family history of sudden infant death syndrome (SIDS), and those who are hard to wake up from sleep. Avoid tanning booths and sunlamps. Geriatric Symptoms can include: Research in animals has shown adverse effects to the fetus when the mother takes the drug. Promethazine Images. There havent been enough studies done in humans to be certain how the drug might affect the fetus. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. How long does promethazine stay in your system? This is because Promethegan is available only as rectal suppositories. It doesnt have a brand-name version. Call your doctor right away if you have serious side effects. Promethazine oral tablet can interact with other medications, vitamins, or herbs you may be taking. Some allergies tend to disappear as a person ages, but many are lifelong. Ask your pharmacist about using those products safely. Be sure to avoid doing this when the weather is very hot or very cold. How far past the expiration date can you use unopened estradiol. You can learn more about how we ensure our content is accurate and current by reading our. Some products that may interact with this drug include: antihistamines applied to the skin (such as diphenhydramine cream, ointment, spray), metoclopramide. Keep all medications away from children and pets. (A left-handed person should lie on the right side and raise the left knee.). To learn more about the cost of promethazine, talk with your pharmacist or health insurance provider. Suppositories: Store refrigerated between 2C and 8C (36F and 46F). Check with your pharmacist. This drug should not be given to a pregnant woman within 2 weeks of delivery because it raises the risk of bleeding in the newborn. Generic alternatives may be available. You should not need a new prescription for this medication to be refilled. Drug classes: Antihistamines, Phenothiazine antiemetics. If youre taking this drug to prevent or treat nausea and vomiting, motion sickness, pain, or to lessen anxiety and promote sleep, you should experience relief of your symptoms. Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. what signs you had. Call your child's doctor immediately and get emergency medical treatment if your child has difficulty breathing, wheezes, slows or pauses in breathing, or stops breathing. Learn more. The cost may also vary based on where you have your prescription filled. Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). you should know that this medication may make you drowsy. Several articles containing formulations and evidence of transdermal absorption are available. Promethazine is used to relieve the symptoms of allergic reactions such as allergic rhinitis (runny nose and watery eyes caused by allergy to pollen, mold or dust), allergic conjunctivitis (red, watery eyes caused by allergies), allergic skin reactions, and allergic reactions to blood or plasma products. Promethazine is used to prevent and treat nausea and vomiting related to certain conditions (such as motion sickness, or before/after surgery). Unwrap and insert one suppository rectally as directed by your doctor, usually 2 to 4 times daily. These can include dry mouth, constipation, trouble emptying your bladder, blurred vision, and drowsiness. Amelioration of allergic reactions to blood or plasma. Why Does Spinach Give Me Diarrhea. Safety and efficacy have not been established in children below 2 years of age. Can diet help improve depression symptoms? Erectile dysfunction (ED) is often a symptom . If you notice other effects not listed above, contact your doctor or pharmacist. Do not double doses. The application area should be covered with an occlusive, nonabsorbent dressing (eg, Tegaderm [3M], Opsite [Smith & Nephew]). Do not double the dose to catch up. This medication comes as tablets, oral syrup, intramuscular (as a shot, IM), and intravenous (given in a vein, IV) formulations. Promethazine helps control symptoms, but will not treat the cause of the symptoms or speed recovery. These drugs are often used to treat similar conditions. Hold it in place for a few moments. This can be harmful or prevent the drug from working well. Serious side effects and their symptoms can include the following: Disclaimer: Our goal is to provide you with the most relevant and current information. The dose is usually 6.25 to 12.5 mg three times a day; or 25 mg at bedtime as needed. This medication may rarely cause a very serious condition called neuroleptic malignant syndrome (NMS). In children this age, this drug may cause slowed breathing that could be fatal. Always carry your medication with you. It can cause skin reactions, digestive symptoms, and breathing difficulties. Promethazine may also be taken at bedtime the night before surgery to relieve anxiety and produce quiet sleep. Tell your doctor about the allergy and Do not keep outdated medicine or medicine no longer needed. The dose may be repeated eight to twelve hours later if needed. C max was significantly lower for the 50-mg suppository (range, 1.0-34 ng/mL) than for the oral syrup. Also tell your doctor and pharmacist if you have ever had an unusual or unexpected reaction when you took promethazine, another phenothiazine, or any other medication. FDA warning: Breathing problems in young children. It can also be used to help you relax or to reduce pain before, during, and after a surgery. This includes your doctors, nurses, pharmacists, and dentists. Tell your Use with care in children 2 years of age and older. This branded product is no longer on the market. This drug can cause a severe allergic reaction. If suppository is soft, chill in a refrigerator or run cold water over it. Talk to your doctor about the risks of giving promethazine to your child. You should always consult your doctor or other healthcare professional before taking any medication. For allergies, this medication may be used once daily at bedtime to avoid being drowsy during the day. This drug can often cause excitement in young children instead of drowsiness. Your dosage, drug form, and how often you take the drug will depend on: It has not been confirmed that promethazine is safe and effective for use in children younger than 2 years. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Remove the wrapper. The generic is considered to be as safe and effective as the original drug. A med that is injected into the vein is referred to as. Medically reviewed by Drugs.com. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. taken, how much, and when it happened. Use. aPLO combination gel (eg, 20% Polox gel with Lipoil 24% [Fagron]). Some children who have taken this drug at the recommended dosages have had hallucinations and seizures. The dosage is based on your age, medical condition, and response to treatment. Signs of an allergic reaction, like rash; Trouble controlling body movements, twitching, change in balance, trouble swallowing or speaking. Properly discard this product when it is expired or no longer needed. This is an emergency and may result in irreversible vision loss. The risk of serious side effects (such as slow/shallow breathing, severe drowsiness/dizziness) may be increased if this medication is used with other products that may also cause drowsiness or breathing problems. Some Medicare plans may help cover the cost of mail-order medications. Promethazine (also called Phenergan ) is used to treat nausea and vomiting. Angioedema (buildup of fluid deep in your skin or underneath your skin). WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. When the weather is hot, drink a lot of fluids and dress lightly. On other days of travel, 25 mg may be taken on arising and again before the evening meal. Do not share your drugs with others and do not take anyone else's drugs. Promethazine HCl has significant anticholinergic activity and is used as an antinauseant and antihistamine as well as for pre- and postoperative sedation and adjunctive therapy in pain relief. Tell your doctor if your condition does not improve or if it worsens. These side effects include dry mouth, constipation, trouble emptying your bladder, blurred vision, and drowsiness. Caution should also be used when giving this drug to children older than 2 years. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses. Symptoms of ED include. When promethazine is used to treat or prevent nausea and vomiting it is usually taken every 4 to 6 hours as needed. When you take drugs called tricyclic antidepressants with promethazine, you may have drowsiness that is more extreme and lasts longer. Here are some options to help lower the long-term costs of promethazine. This content does not have an English version. Children younger than 2 years of ageUse and dose must be determined by your doctor . In children, the drug can cause hyperexcitability and nightmares. any drug without checking with your doctor. When flying, never put it into a checked bag. The more common side effects that can occur with promethazine oral tablet include: If these effects are mild, they may go away within a few days or a couple of weeks. Drug information provided by: Merative, Micromedex. Symptoms can include: Decreased platelet and white blood cell production. You can learn more about how we ensure our content is accurate and current by reading our. Which oral dosage form is held in the mouth until it dissolves? Extrapyramidal symptoms (uncontrollable movements). If your dose is different, do not change it unless your doctor tells you to do so. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. All rights reserved. tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. A: Promethazine HCl is a phenothiazine antihistamine. Do not try to swallow the suppositories or insert in any other part of your body. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. This means the level of this drug in your body could get too high. Promethazine, a phenothiazine, is associated with a possible risk for QT prolongation. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Promethazine is a generic drug, which is an exact copy of the active drug in a brand-name medication. It is also important information to carry with you in case of emergencies. Talk to your doctor if you take other drugs that can cause seizures. This includes bleeding from minor cuts, nose or mouth bleeding, and pinpoint red spots on your skin. Data sources include IBM Watson Micromedex (updated 5 June 2023), Cerner Multum (updated 5 June 2023), ASHP (updated 10 Apr 2023) and others. Pharmacy Times November 2013 Cough & Cold. This raises your risk of side effects. It is indicated for use by patients 2 years and older. Placed between the cheek and gum. Thanks! Now that youve learned about cost and promethazine, you may still have some questions. Symptoms can include: swelling usually around your eyes and lips and sometimes your throat, hands, and feet, swelling on the surface of your skin (welts). Examples of these drugs include: When you take certain nausea and motion sickness drugs with promethazine, certain side effects may increase and last longer. Factors that may affect the price youll pay include your treatment plan, your insurance coverage, and the pharmacy you use. Shakiness, trouble moving around, or stiffness. Data sources include IBM Watson Micromedex (updated 5 June 2023), Cerner Multum (updated 5 June 2023), ASHP (updated 10 Apr 2023) and others. Q: I have a pharmacist in one of my stores looking for a promethazine gel recipe. to you and the baby. This means your doctor will need to get approval from your insurance company before your insurance company will pay for the prescription. What special dietary instructions should I follow? Call your doctor for medical There are other drugs available to treat your condition. How to tell if the drug is working: If youre using this drug for allergies or an allergic reaction, your symptoms, such as sneezing, runny nose, itching, eye tearing, and hives, should decrease or stop. However, many people have no side effects or only have minor side effects. Promethazine can cause severe drowsiness. intravenous. Alcohol can make the side effects of promethazine worse. Examples of these drugs include: When you take certain Parkinsons disease drugs with promethazine, some side effects may increase and last longer. Geometrically levigate the paste in step 3 with the penetration-enhanced vanishing cream. Promethazine may be available through a mail-order pharmacy. 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