Written by Shishira Sreenivas Medically Reviewed by James Beckerman, MD, FACC on July 08, 2022 Medications You Should Avoid When You Have Atrial Fibrillation When you have atrial fibrillation. Amiodarone (Cordarone, Pacerone) is an effective and commonly prescribed antiarrhythmic drug, but it has some marked differences from many other drugs. Overactive bladder is a problem with how your bladder stores urine . Avoid combinations; the risk of the interaction outweighs the benefit. Minimally clinically significant. Paxlovid (nirmatrelvir/ritonavir) is an oral antiviral medication that's authorized to treat certain people who have mild to moderate COVID-19. Examples include deep vein thrombosis (DVT) and pulmonary embolism. A healthcare provider can help assess. We comply with the HONcode standard for trustworthy health information. There are 689 drugs known to interact with amiodarone, along with 11 disease interactions, and 1 alcohol/food interaction. Moderately clinically significant. Check with your doctor if this color change occurs. For aspirin (81 or 325 mg daily) used to prevent heart problems, this is usually safe to stop for seven (7) days prior to any procedure. Drug Info Drug-Drug Interactions Last Updated: March 6, 2023 Ritonavir, a strong cytochrome P450 (CYP) 3A4 inhibitor and a P-glycoprotein inhibitor, is coadministered with nirmatrelvir to increase the blood concentration of nirmatrelvir, thereby making it effective against SARS-CoV-2. You should avoid consuming grapefruits and grapefruit juice while taking amiodarone. Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of amiodarone in the elderly. Does amiodarone interact with my other drugs? Statins rarely cause liver damage, and doctors no longer check liver enzymes for people on statins routinely. Of the total drug interactions, 297 are major, 360 are moderate, and 32 are minor. For example, grapefruit juice can lower the levels of enzymes in your liver responsible for breaking down medications. The antibiotic can lead to higher levels of zolpidem in the body. Take this medicine exactly as directed by your doctor. Drug information provided by: Merative, Micromedex Along with its needed effects, a medicine may cause some unwanted effects. Zolpidem. are known to interact with This interaction can occur with the commonly used statins to lower cholesterol . 689 drugs Paxlovid interacts with many medications. Wellness Mind & Body Supplements That Should Not Be Mixed Supplements might not only interact with each other, but also with medications you may be taking. Uses Precautions. Other common medications that may cause elevated liver enzymes include: Abused drugs such as alcohol, cocaine and anabolic steroids. However, elderly patients are more likely to have age-related kidney, liver, or heart problems, which may require caution and an adjustment in the dose for patients receiving amiodarone. Take this medicine with food or milk to avoid stomach irritation. This drug is used to treat mild to moderate pain (from headaches, menstrual periods, toothaches, backaches, osteoarthritis, or cold/ flu aches and pains) and to reduce fever. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. Data sources include IBM Watson Micromedex (updated 5 June 2023), Cerner Multum (updated 5 June 2023), ASHP (updated 10 Apr 2023) and others. You should avoid consuming grapefruits and grapefruit juice while taking amiodarone. 1 Another patient on colchicine developed fever, diarrhea . 112 drugs Automatically receive FDA alerts, drug interaction warnings, plus data on food, allergy & condition interactions. You'll be closely monitored during this time to make sure that you respond to . Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. If your healthcare provider prescribes this medicine for cardiac arrhythmia, you need to understand the idiosyncrasiesand the risksassociated with it. Tylenol Active drug: acetaminophen Pain reliever ( analgesic) and fever reducer (antipyretic) Used for headaches, fever, muscle aches, backache, toothache, colds Anti-Inflammatories Active drug: ibuprofen, naproxen sodium, or aspirin Reduces pain, fever, and inflammation Used for conditions such as arthritis, bursitis, and tendinitis Tylenol. Highly clinically significant. Amiodarone is used to treat the following conditions: Tylenol is used to treat the following conditions. are known to interact with This medication is used to treat certain bladder problems ( overactive bladder, neurogenic detrusor overactivity). Email this report to a friend, doctor, or patient. Get Pain Relief With the Most Common Arthritis Medications. Usually avoid combinations; use it only under special circumstances. Sign in to your account to save this drug interaction list. Some mixtures of medications can lead to serious and even fatal consequences. Colchicine toxicity is not a pretty sight, and the reported reactions have been life-threatening or fatal. No warnings were found for your selected drugs. Starting dosage: 800-1,600 mg per day taken by mouth in either a single dose or separated doses for 1-3 weeks. Blood levels of an interacting drug may rise, leading to toxicity. Amiodarone may be taken with or without food but should be taken at the same way each time. Although not all of these side effects may occur, if they do occur they may need medical attention. Enter other medications to view a detailed report. Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum. This report displays the potential drug interactions for the following 2 drugs: No interactions were found between amiodarone and Tylenol. Common examples are medications that treat high cholesterol, high blood pressure, and migraines. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor. It is safe to take acetaminophen (Tylenol) before an endoscopy for arthritis pain or headaches. Always consult your healthcare provider. There's not enough information to say that other herbal remedies or supplements are safe to take with amlodipine. To do so may increase the chance for unwanted effects. This may seem odd, but certain medications can interact with foods or beverages. amiodarone. You should not eat grapefruit or drink grapefruit . A total of However, this does not necessarily mean no interactions exist. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. This happens because ciprofloxacin interferes with zolpidem's metabolism (breakdown), making it stay in your body longer. Breastfeeding A total of Available for Android and iOS devices. Grapefruit and grapefruit juice may increase the side effects of amiodarone by increasing the amount of this medicine in your body. Tylenol is used to treat the following conditions: Fever Muscle Pain Pain Sciatica Drug and food interactions Major amiodarone food Applies to: amiodarone Amiodarone may be taken with or without food but should be taken at the same way each time. Add your drug list to My Med List to view medical information in a simple, easy-to-read, personalized format. This color will usually fade after treatment with amiodarone has ended, although it may take several months. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. Jose Luis Pelaez Inc. / Getty Images One patient on colchicine was admitted with fever, diarrhea, myalgia, and abdominal pain 4 days after starting clarithromycin. Ciprofloxacin can interact with zolpidem (Ambien), a common sleep medication used to treat insomnia. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Some interactions occur because one substance causes another substance to have . This can affect the rhythm of your heart. Grapefruit can raise the levels of amiodarone in your body and lead to dangerous side effects. St John's wort, a herbal remedy taken for depression, is thought to affect the way amlodipine works. Drug levels increased by up to 84%, compared with those not drinking the juice ( 9 ). Uses. He subsequently developed multiorgan failure and died. Call your doctor if you have symptoms of irregular heartbeat, chest tightness, blurred vision or nausea. Like other drugs, Xarelto may have interactions. To view an interaction report containing 4 (or more) medications, please sign in or create an account. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Statins include the medications simvastatin, atorvastatin, pravastatin and lovastatin. Side Effects. Talk to your doctor if you're thinking about taking St John's wort. 7. A study gave 11 men who were taking amiodarone a glass of grapefruit juice (about 300 mL). A simple, easy-to-read, personalized format of Available for Android and iOS devices safe to take acetaminophen ( ). 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