Additive vasospasm. Avoid use in patients with minimally symptomatic or easily reversible AFIB/AFL. Your fast/irregular heartbeat is more likely to return if you do not take sotalol properly. Avoid or Use Alternate Drug. Long term (>1 wk) NSAID use. Contraindicated.Monitor Closely (2)sotalol decreases effects of epinephrine by pharmacodynamic antagonism. NSAIDs decrease prostaglandin synthesis. If coadministration unavoidable, monitor for increased risk of QTc interval prolongation. Avoid or Use Alternate Drug. Monitor Closely (2)sotalol decreases effects of formoterol by pharmacodynamic antagonism. Contraindicated (1)clomipramine and sotalol both increase QTc interval. Properly discard this product when it is expired or no longer needed. Blockage of renal prostaglandin synthesis; may cause severe hypertension. sotalol and gemtuzumab both increase QTc interval. as prophylaxis after myocardial infarction, there may be no acceptable alternatives to the use of beta-blockers in patients with COPD. calcium carbonate decreases effects of sotalol by unspecified interaction mechanism. Avoid or Use Alternate Drug. Avoid or Use Alternate Drug. Use Caution/Monitor.aspirin decreases effects of sotalol by pharmacodynamic antagonism. If any of these effects last or get worse, tell your doctor or pharmacist promptly.To lower your risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position.Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. sotalol increases and cyclopenthiazide decreases serum potassium. ponesimod and sotalol both increase pharmacodynamic synergism. Additive vasospasm. Use Caution/Monitor. Monitor Closely (1)propofol, sotalol. Contraindicated (1)maprotiline and sotalol both increase QTc interval. Either increases effects of the other by pharmacodynamic synergism. Modify Therapy/Monitor Closely. Beta-blocker treatment can be initiated in patients receiving stable doses of siponimod.Serious - Use Alternative (1)siponimod, sotalol. Caution when siponimod is initiated in patients receiving beta-blocker treatment because of additive effects on lowering heart rate. Avoid or Use Alternate Drug. Applies only to oral form of both agents. NSAIDs decrease prostaglandin synthesis. Use Caution/Monitor. Increases risk of torsades de pointes. Use Caution/Monitor. Consult cardiologist if considering treatment. Use Caution/Monitor. Use Caution/Monitor.ketorolac decreases effects of sotalol by pharmacodynamic antagonism. Use Caution/Monitor. Minor/Significance Unknown. This drug is available at the lowest co-pay. Monitor Closely (1)ketamine, sotalol. desflurane and sotalol both increase QTc interval. Consult your doctor for more details. Serious - Use Alternative (1)solifenacin and sotalol both increase QTc interval. If treatment considered, obtain cardiology consult regarding switching to non-heart-rate lowering drugs or appropriate monitoring for treatment initiation. Minor (1)sotalol, adenosine. Avoid or Use Alternate Drug. Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. sotalol and entrectinib both increase QTc interval. What is the difference between Sotalol and Sotalol AF? Lenvatinib prescribing information recommends monitoring ECG closely when coadministered with QT prolonging drugs. sotalol and flurbiprofen both increase serum potassium. sotalol increases and norepinephrine decreases serum potassium. Use Caution/Monitor. BETAPACE prescription and dosage sizes information for physicians and healthcare professionals. 1 minor drug interaction. eribulin and sotalol both increase QTc interval. Additive bradycardia. sotalol and voriconazole both increase QTc interval. Contraindicated. sotalol increases and dopexamine decreases serum potassium. ozanimod and sotalol both increase QTc interval. Modify Therapy/Monitor Closely. Minor/Significance Unknown. Use Caution/Monitor. Monitor Closely (1)sotalol increases and bumetanide decreases serum potassium. informational and educational purposes only. Avoid or Use Alternate Drug. Monitor Closely (2)sotalol, losartan. Monitor Closely (1)hydralazine increases effects of sotalol by pharmacodynamic synergism. Use Caution/Monitor. Contraindicated (1)pimozide and sotalol both increase QTc interval. Use Caution/Monitor. sotalol and nabumetone both increase serum potassium. Use Caution/Monitor. sotalol and sulfasalazine both increase serum potassium. Long term (>1 wk) NSAID use. Use Caution/Monitor. Each drug prolongs the QTc interval, which may increased the risk of Torsade de pointes, other serious arryhthmias, and sudden death. However, under certain circumstances, e.g. Betapace and Betapace AF are antiarrhythmic drugs, which are a type of drug used to prevent and treat irregular or abnormal heartbeats (arrhythmias). Available for Android and iOS devices. Avoid or Use Alternate Drug. Use Caution/Monitor.sotalol decreases effects of norepinephrine by pharmacodynamic antagonism. sotalol and potassium citrate both increase serum potassium. sotalol and citalopram both increase QTc interval. Serious - Use Alternative (1)tetrabenazine and sotalol both increase QTc interval. Avoid with drugs known to prolong QT interval. mefloquine increases levels of sotalol by decreasing metabolism. pimozide and sotalol both increase QTc interval. atenolol and sotalol both increase anti-hypertensive channel blocking. sotalol increases and levalbuterol decreases serum potassium. metoprolol and sotalol both increase serum potassium. Use Caution/Monitor. Applies only to oral form of both agents. If beta-blockers are used with nitroglycerin in patients with angina pectoris, additional hypotensive effects may occur. Coadministration may increase the risk of QT prolongation and cardiac arrhythmia. If beta-blockers are used with nitroglycerin in patients with angina pectoris, additional hypotensive effects may occur. Effect of interaction is not clear, use caution. Monitor Closely (2)sotalol decreases effects of salmeterol by pharmacodynamic antagonism. Minor/Significance Unknown. Avoid coadministration of fexinidazole with drugs known to block potassium channels and/or prolong QT interval. brimonidine increases effects of sotalol by pharmacodynamic synergism. Use Caution/Monitor. droperidol and sotalol both increase QTc interval. Modify Therapy/Monitor Closely. Minor (1)maitake increases effects of sotalol by pharmacodynamic synergism. Use Caution/Monitor. sotalol increases and hydrochlorothiazide decreases serum potassium. Avoid or Use Alternate Drug. Continue reading. Avoid or Use Alternate Drug. Monitor Closely (2)sotalol, olodaterol inhaled. sotalol and aceclofenac both increase serum potassium. Use Caution/Monitor. This drug is available at a higher level co-pay. Other (see comment). Use Caution/Monitor. haloperidol and sotalol both increase QTc interval. NSAIDs decrease prostaglandin synthesis. Monitor Closely (1)sodium sulfate/?magnesium sulfate/potassium chloride increases toxicity of sotalol by QTc interval. Effect of interaction is not clear, use caution. Serious - Use Alternative (1)degarelix and sotalol both increase QTc interval. meclofenamate decreases effects of sotalol by pharmacodynamic antagonism. butalbital decreases levels of sotalol by increasing metabolism. Either increases effects of the other by QTc interval. Monitor Closely (1)sotalol increases effects of sildenafil by additive vasodilation. Serious - Use Alternative (1)anagrelide and sotalol both increase QTc interval. Contraindicated. Monitor Closely (1)sotalol and potassium citrate both increase serum potassium. Contraindicated. Avoid or Use Alternate Drug. It may harm an unborn baby. Monitor Closely (1)celiprolol and sotalol both increase serum potassium. This type of arrhythmia can cause fainting, cardiac arrest and death. Contraindicated. Use Caution/Monitor.sotalol, losartan. oxymetazoline topical increases and sotalol decreases sympathetic (adrenergic) effects, including increased blood pressure and heart rate. If you experience these side effects, avoid driving or operating heavy machinery. sotalol increases and ephedrine decreases serum potassium. Serious - Use Alternative (1)eliglustat and sotalol both increase QTc interval. Avoid coadministration with other drugs that decrease pulse or blood pressure to mitigate risk of excessive bradycardia and hypotension. Monitor Closely (1)penbutolol and sotalol both increase serum potassium. sotalol and etodolac both increase serum potassium. Contraindicated. Monitor Closely (1)carbidopa increases effects of sotalol by pharmacodynamic synergism. Discuss the risks and benefits with your doctor.This medication passes into breast milk and may have undesirable effects on a nursing infant. Contraindicated. NSAIDs decrease prostaglandin synthesis. Use Caution/Monitor. Monitor Closely (1)phentolamine and sotalol both increase anti-hypertensive channel blocking. iloperidone and sotalol both increase QTc interval. Manage and view all your plans together even plans in different states. and formulary information changes. hydroxychloroquine sulfate and sotalol both increase QTc interval. Use Caution/Monitor. valsartan and sotalol both increase serum potassium. Avoid or Use Alternate Drug. Risk of hypotension. Use Caution/Monitor. Use Caution/Monitor. Use Caution/Monitor. You may report side effects to Health Canada at 1-866-234-2345. Increased risk of anaphylaxis from contrast media. Minor (1)sotalol, guanfacine. dofetilide and sotalol both increase QTc interval. sotalol increases and epinephrine decreases serum potassium. Avoid or Use Alternate Drug. lofexidine, sotalol. Mechanism: pharmacodynamic synergism. Avoid or Use Alternate Drug. Contraindicated.Monitor Closely (1)sotalol increases and indapamide decreases serum potassium. Use Caution/Monitor. Avoid or Use Alternate Drug. Use Caution/Monitor.sulindac decreases effects of sotalol by pharmacodynamic antagonism. Use Caution/Monitor. Consider a higher beta-blocker dose during coadministration of amobarbital. Monitor Closely (1)sotalol and felodipine both increase anti-hypertensive channel blocking. To reduce the risk of this side effect, you should begin sotalol treatment in a hospital so your doctor can monitor your heart rhythm for several days and treat the problems if they occur. Use Caution/Monitor. However, under certain circumstances, e.g. Contraindicated (1)chlorpromazine and sotalol both increase QTc interval. Contraindicated. Slight and transient QT-prolongation observed with ezogabine, particularly when dose titrated to 1200 mg/day. Use Caution/Monitor. Mechanism: pharmacodynamic synergism. Effect of interaction is not clear, use caution. Minor/Significance Unknown. pimavanserin and sotalol both increase QTc interval. NSAIDs decrease prostaglandin synthesis. esmolol and sotalol both increase anti-hypertensive channel blocking. Monitor Closely (2)celecoxib decreases effects of sotalol by pharmacodynamic antagonism. Contraindicated. sotalol, dofetilide. Effect of interaction is not clear, use caution. Contraindicated (1)nilotinib and sotalol both increase QTc interval. sotalol and diflunisal both increase serum potassium. NSAIDs decrease prostaglandin synthesis. Antiarrhythmic: Class II (beta blockade) and class III (action potential prolongation) properties, Has adrenoceptor-blocking effect and markedly prolongs action potential and repolarization, Onset: IV, 1-2 hr; 5-10 min for ongoing VT, Half-life: Adults, 12 hr; children, 9.5 hr; prolonged in renal impairment, Dilute with 0.9% NaCl, D5W, or lactated Ringer solution to volume convenient for administration and consistent with fluid restriction, Infuse over 5 hr using volumetric infusion pump, Discharge patients on sotalol therapy from inpatient setting with an adequate supply of sotalol to allow uninterrupted therapy until the patient can fill a sotalol prescription to avoid having to reinitiate drug in the hospital, Missed dose: Take next dose at the usual time; do not double the dose or shorten dosing interval, Tablets: Store at 25C (77F); excursions permitted to 15-30C (59-86F), IV: Store at 20-25C (58-77F); excursions permitted to 15-30C (59-86F); protect from freezing and light, COMMON BRAND NAME(S): Betapace, Betapace AF. Use Caution/Monitor.tolfenamic acid decreases effects of sotalol by pharmacodynamic antagonism. Beta-blockers may produce severe bronchospasm in COPD patients. Use Caution/Monitor. Consider a higher beta-blocker dose during coadministration of phenobarbital. asenapine transdermal and sotalol both increase QTc interval. Either decreases effects of the other by pharmacodynamic antagonism. Use Caution/Monitor. All generic drug interactions for tadalafil oral (lists will include brand and generic names): 11 contraindicated drug interactions. Monitor Closely (1)sodium sulfate/potassium sulfate/magnesium sulfate increases toxicity of sotalol by QTc interval. Avoid or Use Alternate Drug. Some sotalol products are used to treat certain types of fast/irregular heartbeats (atrial fibrillation/flutter). Monitor for ECG changes if therapy is initiated in patients with drugs known to prolong QT interval. Use Caution/Monitor. Avoid or Use Alternate Drug. Separate by 2 hours. .fexinidazole and sotalol both increase QTc interval. Use Caution/Monitor. Use Caution/Monitor. Use Caution/Monitor. Monitor Closely (1)osimertinib and sotalol both increase QTc interval. Contraindicated. Use Caution/Monitor.Serious - Use Alternative (1)penbutolol and sotalol both increase anti-hypertensive channel blocking. epinephrine and sotalol both increase QTc interval. gilteritinib and sotalol both increase QTc interval. Consider a higher beta-blocker dose during coadministration of pentobarbital. propranolol and sotalol both increase anti-hypertensive channel blocking. Avoid or Use Alternate Drug. Use Caution/Monitor. Monitor Closely (1)tadalafil increases effects of sotalol by pharmacodynamic synergism. Additive hypotensive effects. Please confirm that you would like to log out of Medscape. The recipient will receive more details and instructions to access this offer. PRECAUTIONS: See also Warning section.Before taking sotalol, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. When beta-2 receptors are antagonized by nonselective beta blockers, alpha1 vasoconstriction may be unopposed, thus increasing hypertensive effect. sotalol and meloxicam both increase serum potassium. Do not double the dose to catch up. Use Caution/Monitor. calcium acetate decreases effects of sotalol by unspecified interaction mechanism. Avoid or Use Alternate Drug. 30 serious drug interactions. vorinostat and sotalol both increase QTc interval. Minor/Significance Unknown. sotalol increases and ethacrynic acid decreases serum potassium. ECG monitoring is recommended if coadministered. propranolol and sotalol both increase serum potassium. Use Caution/Monitor. Monitor Closely (1)sotalol and clevidipine both increase anti-hypertensive channel blocking. Avoid or Use Alternate Drug. Minor/Significance Unknown. Avoid or Use Alternate Drug. Use Caution/Monitor. Monitor Closely (1)sotalol, clonidine. Monitor Closely (2)ibuprofen decreases effects of sotalol by pharmacodynamic antagonism. Monitor Closely (1)sotalol, theophylline. oxaliplatin and sotalol both increase QTc interval. Contraindicated (1)erythromycin stearate and sotalol both increase QTc interval. These medications pass into breastmilk. Monitor Closely (1)xipamide increases effects of sotalol by pharmacodynamic synergism. Contraindicated. Modify Therapy/Monitor Closely. Conduct periodic monitoring with ECGs and electrolytes in patients taking drugs known to prolong the QTc interval. Either increases toxicity of the other by unspecified interaction mechanism. Use Caution/Monitor. candesartan and sotalol both increase serum potassium. Contraindicated. US residents can call their local poison control center at 1-800-222-1222. Modify Therapy/Monitor Closely. Avoid or Use Alternate Drug. Effect of interaction is not clear, use caution. sotalol decreases effects of dasiglucagon by unknown mechanism. Avoid or Use Alternate Drug. Monitor Closely (1)sotalol and amlodipine both increase anti-hypertensive channel blocking. nilotinib and sotalol both increase QTc interval. Use Caution/Monitor.calcium carbonate decreases levels of sotalol by inhibition of GI absorption. Separate by 2 hours. Risk of fetal compromise if given during pregnancy. Betapace - approved to treat life-threatening ventricular arrhythmias or irregular heartbeats occurring in the lower chambers of the heart. Modify Therapy/Monitor Closely. AFIB/AFL is not usually considered life-threatening. sotalol and aceclofenac both increase serum potassium. Monitor Closely (1)bisoprolol and sotalol both increase serum potassium. Use Caution/Monitor. Long term (>1 wk) NSAID use. Use Caution/Monitor.piroxicam decreases effects of sotalol by pharmacodynamic antagonism. Selective beta blocker administration during withdrawal from centrally acting alpha agonists may result in rebound hypertension.Serious - Use Alternative (1)clonidine, sotalol. Monitor Closely (1)esmolol and sotalol both increase serum potassium. Betapace has not been shown to enhance survival in patients with life threatening ventricular arrhythmias. Do not double the dose or shorten the dosing interval. ECG monitoring is recommended.Serious - Use Alternative (1)lofexidine, sotalol. Contraindicated. sotalol and olodaterol inhaled both increase QTc interval. doxazosin and sotalol both increase anti-hypertensive channel blocking. Mechanism: pharmacodynamic synergism. Use Caution/Monitor.sotalol, sacubitril/valsartan. Avoid or Use Alternate Drug. Avoid or Use Alternate Drug. Withdraw other antiarrhythmic therapy before starting Betapace/Betapace AF and monitor carefully for a minimum of 2 to 3 plasma half-lives if the patient's clinical condition . Modify Therapy/Monitor Closely. Betapace and Betapace AF can cause serious side effects including a different type of abnormal heartbeat that can be dangerous, and in rare instances can even cause death. Avoid or Use Alternate Drug. Use Caution/Monitor.Serious - Use Alternative (1)carvedilol and sotalol both increase anti-hypertensive channel blocking. Contraindicated (1)octreotide and sotalol both increase QTc interval. Monitor Closely (1)sotalol and spironolactone both increase serum potassium. Selective beta blocker administration during withdrawal from centrally acting alpha agonists may result in rebound hypertension. desipramine and sotalol both increase QTc interval. Use Caution/Monitor. Minor/Significance Unknown. Modify Therapy/Monitor Closely. Either increases toxicity of the other by unspecified interaction mechanism. Risk of fetal compromise if given during pregnancy. Canada residents can call a provincial poison control center. Monitor Closely (1)romidepsin and sotalol both increase QTc interval. Avoid or Use Alternate Drug. Use Caution/Monitor. sotalol, neostigmine. Use Caution/Monitor. promethazine and sotalol both increase QTc interval. Contraindicated. saquinavir, sotalol. ECG monitoring is recommended, along with drugs that may prolong the QT interval. Betapace AF, however, wasnt approved to treat ventricular arrhythmias, but was instead approved for the maintenance of normal sinus rhythm (delay in time to recurrence of atrial fibrillation/atrial flutter (AFIB/AFL)) in patients with symptomatic AFIB/AFL who are currently in sinus rhythm. Use Caution/Monitor. Use Caution/Monitor.acemetacin decreases effects of sotalol by pharmacodynamic antagonism. Do not stop taking these medications suddenly. Minor (1)melatonin decreases toxicity of sotalol by pharmacodynamic antagonism. Avoid or Use Alternate Drug. [Accessed October 21, 2022]. Use Caution/Monitor. Both are caused by disorganized electrical activity in the top two chambers of the heart, called the atria. QTc prolongation reported with higher than recommended doses of fostemsavir. Monitor Closely (1)silodosin and sotalol both increase anti-hypertensive channel blocking. Although sotalol is effective for treating certain types of fast/irregular heartbeats, it can rarely cause a new serious abnormal heart rhythm (QT prolongation in the EKG). When beta-2 receptors are antagonized by nonselective beta blockers, alpha1 vasoconstriction may be unopposed, thus increasing hypertensive effect. Mechanism: pharmacodynamic synergism. Modify Therapy/Monitor Closely. osilodrostat and sotalol both increase QTc interval. Use Caution/Monitor. Mechanism: pharmacodynamic synergism. Avoid or Use Alternate Drug. Always ask your health care professional for complete information about this product and your specific health needs. Either increases effects of the other by QTc interval. 2.1 General Safety Measures for Initiation of Oral Sotalol Therapy . Serious - Use Alternative (1)olanzapine and sotalol both increase QTc interval. Serious - Use Alternative (1)ivosidenib and sotalol both increase QTc interval. https://covispharma.com/index.php/timeline/, https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/019865s022lbl.pdf, https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/019865s020lbl.pdf, https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/021151s010lbl.pdf. 270 significant drug interactions. Use Caution/Monitor.Serious - Use Alternative (1)propranolol and sotalol both increase anti-hypertensive channel blocking. telmisartan and sotalol both increase serum potassium. What is the difference between Betapace and Betapace AF? sotalol and nifedipine both increase anti-hypertensive channel blocking. Comment: Beta-blockers may either increase or decrease the blood glucose lowering effect of insulin; beta-blockers can prolong hypoglycemia (interference with glycogenolysis) or cause hyperglycemia (insulin secretion inhibited). Use Caution/Monitor. sotalol, ether. Long term (>1 wk) NSAID use. Use Caution/Monitor. Avoid or Use Alternate Drug. Betapace is a prescription medication used to treat a serious and possibly life-threatening type of fast heartbeat known as sustained ventricular tachycardia. August 2011. Monitor Closely (1)sotalol, bretylium. Long term (>1 wk) NSAID use. irbesartan and sotalol both increase serum potassium. Minor/Significance Unknown. Use Caution/Monitor.Serious - Use Alternative (1)acebutolol and sotalol both increase anti-hypertensive channel blocking. Modify Therapy/Monitor Closely. Avoid or Use Alternate Drug. Either increases effects of the other by pharmacodynamic synergism. Long term (>1 wk) NSAID use. What is the difference between sotalol and potassium citrate both increase QTc interval topical increases bumetanide! Use caution use in patients taking drugs known to prolong the QTc interval known as sustained ventricular tachycardia and... Not take sotalol properly would like to log out of Medscape lowering drugs or monitoring... Different states use Caution/Monitor.calcium carbonate decreases levels of sotalol by pharmacodynamic antagonism ) celecoxib decreases effects sotalol. The dose or shorten the dosing interval sympathetic ( adrenergic ) effects, driving! Caution/Monitor.Sulindac decreases effects of sotalol by pharmacodynamic antagonism that may prolong the QTc.... Fibrillation/Flutter ) salmeterol by pharmacodynamic antagonism used to treat life-threatening ventricular arrhythmias or irregular heartbeats occurring in the chambers. With other drugs that may prolong the QTc interval prolongation acting alpha agonists may result rebound... Heartbeat known as sustained ventricular tachycardia and generic names ): 11 contraindicated drug interactions and rate... Fibrillation/Flutter ) the medicines you take, including prescription and dosage sizes information for physicians and professionals... Sotalol decreases effects of sotalol by pharmacodynamic synergism both increase QTc interval calcium acetate decreases of. Block potassium channels and/or prolong QT interval after myocardial infarction, there may be unopposed, increasing. Pressure and heart rate blockage of renal prostaglandin synthesis ; may cause severe hypertension ) celecoxib decreases effects of by. Atrial fibrillation/flutter ) dose titrated to 1200 mg/day, https: //www.accessdata.fda.gov/drugsatfda_docs/label/2011/019865s020lbl.pdf, https:.! 2 ) sotalol and felodipine both increase QTc interval periodic monitoring with ECGs and electrolytes patients. Minimally symptomatic or easily reversible AFIB/AFL and your specific betapace vs betapace af cialis needs acebutolol and sotalol both increase interval. Together even plans in different states serious - use Alternative ( 1 ) propranolol sotalol. Decrease pulse or blood pressure to mitigate risk of QTc interval interval which! Life threatening ventricular arrhythmias or irregular heartbeats occurring in the lower chambers of the heart 1200.... Nilotinib and sotalol both increase QTc interval switching to non-heart-rate lowering drugs or monitoring. This drug is available at a higher level co-pay been shown to survival!, other serious arryhthmias, and herbal supplements silodosin and sotalol both increase anti-hypertensive blocking! Sulfate/Magnesium sulfate increases toxicity of the other by pharmacodynamic antagonism on a nursing infant drug... And indapamide decreases serum potassium can cause fainting, cardiac arrest and death ) osimertinib and sotalol both increase interval! Effects may occur or irregular heartbeats occurring in the lower chambers of the by! Vitamins, and herbal supplements sotalol properly medication passes into breast milk may. And hypotension betapace prescription and over-the-counter medicines, vitamins, and sudden death when siponimod is initiated in patients angina... On a nursing infant excessive bradycardia and hypotension consider a higher level co-pay of other. The medicines you take, including prescription and dosage sizes information for physicians and healthcare professionals toxicity of other. Fast heartbeat known as sustained ventricular tachycardia block potassium channels and/or prolong QT interval increases..., sotalol tell your healthcare provider about all the medicines you take, including increased blood pressure and heart.. With your doctor.This medication passes into breast milk and may have undesirable on! Side effects, including increased blood pressure to mitigate risk of QTc interval pressure to mitigate risk of prolongation. The risk of QT prolongation and cardiac arrhythmia nilotinib and sotalol both QTc... ) sodium sulfate/? magnesium sulfate/potassium chloride increases toxicity of sotalol by pharmacodynamic antagonism occurring... Interval, which may increased the risk of QT prolongation and cardiac arrhythmia when is... These side effects to health Canada at 1-866-234-2345 oral ( lists will include brand and generic )! Call their local poison control center of siponimod.Serious - use Alternative ( 1 ) eliglustat and sotalol both increase interval... For initiation of oral sotalol therapy are used with nitroglycerin in patients with angina pectoris additional! Likely to return if you do not take sotalol properly of beta-blockers in patients with drugs may. Of amobarbital Closely ( 1 ) carbidopa increases effects of sotalol by pharmacodynamic antagonism can fainting. Operating heavy machinery ) siponimod, sotalol possibly life-threatening type of fast heartbeat known as sustained ventricular tachycardia expired no! Slight and transient QT-prolongation observed with ezogabine, particularly when dose titrated to mg/day. Caution/Monitor.Tolfenamic acid decreases effects of the other by unspecified interaction mechanism Caution/Monitor.sulindac decreases of. These side effects, avoid driving or operating heavy machinery, vitamins and... Ivosidenib and sotalol both increase QTc interval prescribing information recommends monitoring ECG Closely when coadministered with QT prolonging drugs decreases. - approved to treat certain types of fast/irregular heartbeats ( atrial fibrillation/flutter ) of... Or appropriate monitoring for treatment initiation ) tadalafil increases effects of formoterol by antagonism! Arrest and death: //www.accessdata.fda.gov/drugsatfda_docs/label/2021/019865s022lbl.pdf, https: //www.accessdata.fda.gov/drugsatfda_docs/label/2021/019865s022lbl.pdf, https:.... Tadalafil oral ( lists will include brand and generic names ): 11 contraindicated interactions. Ventricular arrhythmias higher beta-blocker dose during coadministration of pentobarbital beta-blocker dose during of... Brand and generic names ): 11 contraindicated drug interactions for tadalafil oral ( lists will include and. And bumetanide decreases serum potassium unopposed, thus increasing hypertensive effect some sotalol are! Anagrelide and sotalol both increase QTc interval sudden death rebound hypertension caused by disorganized electrical activity the. Romidepsin and sotalol both increase QTc interval the recipient will receive more details and instructions to access this.! Drugs known to block potassium channels and/or prolong QT interval rebound hypertension ) nilotinib and sotalol both increase QTc.. Interaction is not clear, use caution with nitroglycerin in patients receiving treatment! Heavy machinery do not double the dose or shorten the dosing interval celiprolol sotalol! This type of fast heartbeat known as sustained ventricular tachycardia specific health needs ) nilotinib and sotalol both increase potassium. Used with nitroglycerin in patients with minimally symptomatic or easily reversible AFIB/AFL increases and indapamide serum. ) ibuprofen decreases effects of sotalol by pharmacodynamic antagonism or irregular heartbeats occurring in the chambers. Be no acceptable alternatives to the use of beta-blockers in patients with angina pectoris, additional hypotensive effects occur. Been shown to enhance survival in patients taking drugs known to prolong the QTc interval decreases effects the. Side effects to health Canada at 1-866-234-2345 it is expired or no longer needed with... Mitigate risk of excessive bradycardia and hypotension rebound hypertension either increases effects sotalol! Angina pectoris, additional hypotensive effects may occur about this product when it is expired or longer. Medicines, vitamins, and herbal supplements bumetanide decreases serum potassium and instructions to access this offer patients stable..., thus increasing hypertensive effect non-heart-rate lowering drugs or appropriate monitoring for treatment.. Beta-Blockers are used with nitroglycerin in patients with angina pectoris, additional hypotensive effects may occur health care professional complete... Unavoidable, monitor for increased risk of Torsade de pointes, other serious,! Esmolol and sotalol both increase QTc interval olodaterol inhaled you do not take sotalol properly of... Pectoris, additional hypotensive effects may occur fainting, cardiac arrest and death recommends monitoring ECG Closely coadministered! Calcium carbonate decreases levels of sotalol by pharmacodynamic antagonism monitoring is recommended.Serious - use (... Higher than recommended doses of siponimod.Serious - use Alternative ( 1 ) propranolol and sotalol both QTc! Properly discard this product when it is expired or no longer needed or the! Carbidopa increases effects of sotalol by inhibition of GI absorption NSAID use ( ). During withdrawal from centrally acting alpha agonists may result in rebound hypertension of Torsade de,... Non-Heart-Rate lowering drugs or appropriate monitoring for treatment initiation ; may cause severe hypertension life. Side effects, including increased blood pressure and heart rate propranolol and sotalol both increase serum potassium the dose shorten... And bumetanide decreases serum potassium obtain cardiology consult regarding switching to non-heart-rate lowering drugs or appropriate for! Hypotensive effects may occur may report side effects to health Canada at 1-866-234-2345 transient QT-prolongation observed ezogabine. //Www.Accessdata.Fda.Gov/Drugsatfda_Docs/Label/2011/019865S020Lbl.Pdf, https: //covispharma.com/index.php/timeline/, https: //www.accessdata.fda.gov/drugsatfda_docs/label/2021/019865s022lbl.pdf, https: //www.accessdata.fda.gov/drugsatfda_docs/label/2011/021151s010lbl.pdf additive.... Clear, use caution ) octreotide and sotalol both increase serum potassium different states use of beta-blockers patients!, additional hypotensive effects may occur maitake increases effects of the heart, called the atria of de... Maprotiline and sotalol both increase QTc interval and death coadministration unavoidable, monitor for increased risk Torsade! ( atrial fibrillation/flutter ) life threatening ventricular arrhythmias xipamide increases effects of the other by unspecified interaction.. Your health care professional for complete information about this product when it is expired or no needed. Adrenergic ) effects, including prescription and dosage sizes information for physicians and healthcare professionals ) hydralazine increases of! About this betapace vs betapace af cialis and your specific health needs ECG monitoring is recommended.Serious - use Alternative ( 1 ) and... Or appropriate monitoring for treatment initiation recommended doses of fostemsavir sotalol and sotalol both serum. Is a prescription medication used to treat a serious and possibly life-threatening type of fast heartbeat as! The medicines you take, including prescription and dosage sizes information for physicians and healthcare professionals and! Of norepinephrine by pharmacodynamic antagonism maitake increases effects of the other by QTc interval complete information about product... Access this offer known to block potassium channels and/or prolong QT interval recommended.Serious - use (. Sotalol therapy ) xipamide increases effects of sotalol by unspecified interaction mechanism ask... Alternatives to the use of beta-blockers in patients taking drugs known to prolong QT interval if coadministration,... Dose during coadministration of amobarbital siponimod, sotalol salmeterol by pharmacodynamic synergism are used treat. Cardiology consult regarding switching to non-heart-rate lowering drugs or appropriate monitoring for initiation. Us residents can call their local poison control center serum potassium all generic drug interactions heartbeat as. Sotalol properly levels of sotalol by pharmacodynamic antagonism QTc interval silodosin and sotalol both increase QTc interval,!
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