Along with its needed effects, a medicine may cause some unwanted effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Other side effects not listed may also occur in some patients. Save 2.20. Easily compare up to 40 drugs with our drug interaction checker. [, Lucafo M, Stocco G, Martelossi S, Favretto D, Franca R, Malusa N, Lora A, Bramuzzo M, Naviglio S, Cecchin E, Toffoli G, Ventura A, Decorti G: Azathioprine Biotransformation in Young Patients with Inflammatory Bowel Disease: Contribution of Glutathione-S Transferase M1 and A1 Variants. Copyright: Merative US L.P. 1973, 2023. Sorry, we have no data available. And remember to mention youre on azathioprine if youre treated by anyone other than your usual rheumatology team. This is a decision you and your doctor will make. InfectionMay decrease your body's ability to fight infection. Our phase IV clinical studies alone cannot establish cause-effect relationship. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Keep from freezing. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. 2017 Apr;23(4):628-634. doi: 10.1097/MIB.0000000000001051. Azathioprine is a prodrug of 6-mercaptopurine, first synthesized in 1956 by Gertrude Elion, William Lange, and George Hitchings in an attempt to produce a derivative of 6-mercaptopurine with a better therapeutic index. Epub 2017 Aug 12. The serum concentration of Azathioprine can be increased when it is combined with Abametapir. Helps you get and maintain an erection when you need it. Current guidelines say that azathioprine can be taken if trying for a baby and even when pregnant or breastfeeding. Follow your doctor's orders or the directions on the label. [, Wright S, Sanders DS, Lobo AJ, Lennard L: Clinical significance of azathioprine active metabolite concentrations in inflammatory bowel disease. Thrombocytopenia (low number of platelets)Use with caution. Because azathioprine affects the immune system, it can make you more likely to develop infections. Advertising revenue supports our not-for-profit mission. Alcohol and azathioprine can both affect your liver, so its important you dont drink more alcohol than the governments recommended limits. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements. If you have questions about this, talk to your doctor. Using this medicine while you are pregnant can harm your unborn baby. Drug information provided by: Merative, Micromedex. For non-prescription products, read the label or package ingredients carefully. Azathioprine is a prodrug of 6-mercaptopurine, first synthesized in 1956 by Gertrude Elion, William Lange, and George Hitchings in an attempt to produce a derivative of 6-mercaptopurine with a better therapeutic index.9,10,11 Azathioprine is used to treat inflammatory conditions like rheumatoid arthritis and as an immunosuppressant in the prevention of renal transplant rejection.12, Azathiprine was granted FDA approval on 20 March 1968.12, Azathioprine is indicated to treat rheumatoid arthritis and prevent renal transplant rejection.12, Azathioprine is an immunosuppressive agent which functions through modulation of rac1 to induce T cell apoptosis, as well as other unknown immunosuppressive functions.5 It has a long duration of action as it is given daily, and has a narrow therapeutic index.12 Patients should be counselled regarding the risk of malignancies of the skin and lymphomas.12, Azathioprine's mechanism of action is not entirely understood but it may be related to inhibition of purine synthesis, along with inhibition of B and T cells.5, 6-thioguanine triphosphate, a metabolite of azathioprine, modulates activation of rac1 when costimulated with CD28, inducing T cell apoptosis.5 This may be mediated through rac1's action on mitogen-activated protein kinase, NF-kappaB.5, Oral azathioprine is well absorbed, with a Tmax of 1-2h.12 Further data regarding the absorption of azathioprine is not readily available.6,7, Data regarding the volume of distribution of azathioprine is not readily available.6,7, Azathioprine is 30%12 bound to proteins such as human serum albumin in circulation.1, Azathioprine is converted to 6-mercaptopurine nonenzymatically.4 6-mercaptopurine is then metabolized to 6-methylmercaptopurine by thiopurine methyltransferase, 6-thiouric acid by xanthine oxidase, or 6-thiosine-5'-monophosphate by hypoxanthine phosphoribosyltransferase.4 6-thiosine-5'-monophosphate is metabolized to 6-methylthiosine-5'-monophosphate by thiopurine methyltransferase or 6-thioxanthylic acid by inosine monophosphate dehydrogenase.4 6-thioxanthylic acid is metabolized by guanosine monophosphate synthetase to 6-thioguanine monophosphate, the first of the 6-thioguanine nucleotides.4 6-thioguanine monophosphate is phosphorylated to produce the remaining 6-thioguanine nucleotides, 6-thioguanine diphosphate and 6-thioguanine triphosphate.4, Hover over products below to view reaction partners, Azathioprine and mercaptopurine are not detectable in urine after 8 hours.12 Further data regarding the route of elimination of azathioprine are not available.8, The half life of azathioprine is approximately 5 hours.12, Data regarding the clearance of azathioprine is not readily available.6,7, The oral LD50 in mice is 2500mg/kg and in rats is 400mg/kg.12, Patients experiencing an overdose may present with bone marrow hypoplasia, bleeding, and infection, which may progress to death.12 Patients should be treated with supportive and symptomatic treatments. Using azathioprine after these medicines may increase your risk for unwanted effects. vomiting. XIII. In addition, you should not be around other persons living in your household who receive live virus vaccines because there is a chance they could pass the virus on to you. sores, ulcers, or white spots on the lips or in the mouth, greatly decreased frequency of urination or amount of urine, pains in the stomach, side, or abdomen, possibly radiating to the back, unusual feeling of discomfort or illness (sudden). The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. Some reports may have incomplete information. Acetazolamide may increase the excretion rate of Azathioprine which could result in a lower serum level and potentially a reduction in efficacy. It is often used in crohn's disease. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. diarrhoea. . These medications may interact and cause very harmful effects. VLD DANIMANLIK TIBB RNLER VE TANITIM HZMETLER LTD. T. If the TPMT result is very low, azathioprine may not be the right medication for you, and your doctor will discuss other treatment options. InfectionMay decrease your body's ability to fight infection. This survey is being conducted by the WebMD marketing sciences department. 2014 Mar-Apr;71(2):343-9. You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Liver diseaseUse with caution. Do not touch your eyes or the inside of your nose unless you have just washed your hands and have not touched anything else. sensitivity to sunlight. 2000 Jun;21(6):1157-62. Wash your hands often. eHealthMe is studying from 59,605 Azathioprine users for its effectiveness, alternative drugs and more. You should speak to your doctor and surgeon about this first. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. Was 21.99. generic drugs) are not considered. Ulcerative colitisUse with caution. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. While you are being treated with azathioprine, and after you stop treatment with it, do not have any immunizations (vaccines) without your doctor's approval. Keep your mouth clean by brushing your teeth regularly. Azathioprine can temporarily lower the number of white blood cells in your blood, increasing the chance of getting an infection. This risk is higher in people using azathioprine after. It belongs to the group of medicines known as immunosuppressive agents. Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. The metabolism of Azathioprine can be decreased when combined with Acetaminophen. A 6-thioguanine nucleotide threshold level of 400 pmol/8 x 10(8) erythrocytes predicts azathioprine refractoriness in patients with inflammatory bowel disease and normal TPMT activity. If youre concerned, discuss your alcohol intake with your healthcare team. Avoid having live vaccines, such as MMR (measles, mumps and rubella) or yellow fever. Carcinogenesis. Blood and urine tests may be needed to check for unwanted effects. The following information includes only the average doses of this medicine. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. It is usually taken once or twice a day after meals. Make sure your food is stored and prepared properly. [. Using alcohol or tobacco with certain medicines may also cause interactions to occur. All rights reserved. If you believe you are experiencing an interaction, contact a healthcare provider immediately. 2023 eHealthMe.com. You may report side effects to the FDA at 1-800-FDA-1088. All rights reserved. Acta Pol Pharm. Talk to your doctor if you have concerns about this risk. For non-prescription products, read the label or package ingredients carefully. For this medicine, the following should be considered: Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Genes (Basel). Azathioprine is used to prevent your body from rejecting a transplanted kidney. Propargyl-type 1,3-dipolar organic compound, C-nitro compound, aryl sulfide, imidazoles, thiopurine (, Ras-related C3 botulinum toxin substrate 1, L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS, Antineoplastic and Immunomodulating Agents, Nucleic Acids, Nucleotides, and Nucleosides, Propargyl-type 1,3-dipolar organic compounds, Disorder Related to Cardiac Transplantation, Eosinophilic Granulomatosis With Polyangiitis (Churg-Strauss) (EGPA), Predicted MS/MS Spectrum - 10V, Positive (Annotated), Predicted MS/MS Spectrum - 20V, Positive (Annotated), Predicted MS/MS Spectrum - 40V, Positive (Annotated), Predicted MS/MS Spectrum - 10V, Negative (Annotated), Predicted MS/MS Spectrum - 20V, Negative (Annotated), Predicted MS/MS Spectrum - 40V, Negative (Annotated), LC-MS/MS Spectrum - LC-ESI-qTof , Positive, LC-MS/MS Spectrum - LC-ESI-QFT , negative, splash10-004i-0390000000-0d11d23373539cfb283c, splash10-000x-0950000000-b6de6073310270167ffb, splash10-001l-2950000000-4d3fb67844876c217814, Hypoxanthine-guanine phosphoribosyltransferase, Nucleotide triphosphate diphosphatase NUDT15. [, Sahasranaman S, Howard D, Roy S: Clinical pharmacology and pharmacogenetics of thiopurines. BioDrugs. This discomfort is expected and will go away as your body gets used to the medicine. Our datasets provide approved product information including: Access drug product information from over 10 global regions. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Common interactions include pruritus among females and drug ineffective among males. If you can, avoid people with infections. [, Stocco G, Pelin M, Franca R, De Iudicibus S, Cuzzoni E, Favretto D, Martelossi S, Ventura A, Decorti G: Pharmacogenetics of azathioprine in inflammatory bowel disease: a role for glutathione-S-transferase? This medicine may increase your risk of getting certain types of cancer, especially of the skin, lymph system (lymphoma), or blood (leukemia). Appropriate studies have not been performed on the relationship of age to the effects of azathioprine in the pediatric population. Make sure you tell your doctor if you have any other medical problems, especially: Take this medicine exactly as directed by your doctor. It is often used in infection. So make sure to discuss what medications youre on with your rheumatology team, as they might suggest starting you on an alternative DMARD. Make sure you tell your doctor if you have any other medical problems, especially: Portions of this document last updated: Feb. 01, 2023. Am J Gastroenterol 2008; 103:3115. Use of this site constitutes acceptance of eHealthMe.com's terms of service and privacy policy. Azathioprine is an immunosuppressant used to prevent renal transplant rejection, treat rheumatoid arthritis, Crohn's disease, and ulcerative colitis. If you have extreme nausea with vomiting, contact your healthcare provider. Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. It can also affect your blood count or liver. Official answer by Drugs.com People with a sulfa allergy typically need to avoid sulfonamide antibiotics (antibiotics containing sulfa), including: Septra and Bactrim (sulfamethoxazole-trimethoprim) Pediazole (erythromycin-sulfisoxazole) 4 UNI | 4.95 per 1UNI. For this medicine, the following should be considered: Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Chem Biol Interact. Injection, powder, lyophilized, for solution, Ncs Health Care Of Ky, Inc Dba Vangard Labs. Its also known to interact with some medications used to control high blood pressure, such as warfarin. Eur J Clin Pharmacol. It can also affect your blood count or liver. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. Do not take other medicines unless they have been discussed with your doctor. [, Tanaka M, Asahi Y, Masuda S, Ota T: Binding position of azathioprine with bovine serum albumin determined by measuring nuclear magnetic resonance relaxation time. Azathioprine can be prescribed by a consultant rheumatologist for: Azathioprine is usually given as tablets, taken once or twice daily. Severe Interactions These medications are not usually taken together. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. Check with your doctor as soon as possible if you think you are getting an infection or if you get a fever or chills, cough or hoarseness, lower back or side pain, or painful or difficult urination. Azathioprine, sometimes known by other names such as Imuran or Azapress, is a disease-modifying anti-rheumatic drug (DMARD). 3. Some Amino-substituted Derivatives of Guanine and 6-Thioguanine Journal of the American Chemical Society. Some rheumatologists may suggest stricter limits. Some examples of live vaccines include measles, mumps, influenza (nasal flu vaccine), poliovirus (oral form), rotavirus, and rubella. If you think you have become pregnant while using this medicine, tell your doctor right away. Of the total drug interactions, 44 are major, 317 are moderate, and 20 are minor. 2012 Feb;13(2):82-93. doi: 10.1111/j.1751-2980.2011.00556.x. you have infections that repeatedly come and go. Some services may be fulfilled by Versus Arthritis Trading Ltd. Download versus Arthritis: Azathioprine information booklet, disease-modifying anti-rheumatic drug (DMARD), non-steroidal anti-inflammatory drug (NSAID). Make your tax-deductible gift and be a part of the cutting-edge research and care that's changing medicine. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Clinical details: Monitoring Ongoing blood test monitoring of high risk or low risk patients according to monitoring schedules below and review of laboratory abnormalities prior to transfer. Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. The level of risk is uncertain; however, any of these drugs combined with a daily prednisolone dose of 10 mg or above is considered high risk, and self-isolation is recommended. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Warnings Azathioprine may cause a rare type of lymphoma (cancer) of the liver, spleen, and bone marrow that can be fatal. Safety and efficacy have not been established. Wear protective clothing and hats, and stay out of direct sunlight between the hours of 10 am and 3 pm Avoid sunlamps and tanning beds. Severity: Severe Evidence: Study Amsacrine Safety and efficacy have not been established. May increase risk for more side effects. Call your doctor for medical advice about side effects. Consult your healthcare. "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research. Azathioprine oral tablet is used to treat rheumatoid arthritis and to keep your immune system from attacking a new kidney after a transplant. Mayo Clinic on Incontinence - Mayo Clinic Press, Mayo Clinic on Hearing and Balance - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press, Bacillus of Calmette and Guerin Vaccine, Live, Stomach or bowel problems (eg, nausea, vomiting, diarrhea) or. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. The Zostavax shingles vaccine is a live vaccine and isnt usually recommended for people who are on azathioprine, though you may be able to have it if you're on a low dose of azathioprine. These could be symptoms of a serious reaction to the medicine in your bowel. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). Paxlovid interacts with many medications. 2017 Sep 25;275:189-195. doi: 10.1016/j.cbi.2017.08.009. So you'll need to have blood tests before and during your course of azathioprine. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). The use of the eHealthMe site and its content is at your own risk. Talk to your doctor if you have questions about this. Allopurinol Allopurinol potentially increases the risk of haematological toxicity when given with Azathioprine. Using this medicine with any of the following medicines is not recommended. Portions of this document last updated: Feb. 01, 2023, Original article: https://www.mayoclinic.org/drugs-supplements/azathioprine-oral-route/precautions/drg-20067180. Taking too much may increase the chance of unwanted effects, and taking too little will not help your condition. Learn how long they take, uses and side-effects. The absence of an interaction does not necessarily mean no interactions exist. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco. 2003 Apr;111(8):1133-45. You should tell your doctor or nurse specialist straight away if you develop any of the following after starting azathioprine: Contact your rheumatology team if you get chickenpox or shingles, or if you come into come into contact with someone who has them and youve never had chickenpox before. However, the dose is usually not more than 2.5 mg per kg of body weight per day. For non-prescription products, read the label or package ingredients carefully. The dose of this medicine will be different for different patients. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. 2003 Sep;38(9):972-7. doi: 10.1080/00365520310005082. Improve clinical decision support with information on. Because azathioprine affects the immune system, it can make you more likely to develop infections. Summary: Drug interactions are reported among people who take Amoxicillin and Azathioprine. 2008 Aug;64(8):753-67. doi: 10.1007/s00228-008-0478-6. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. The therapeutic efficacy of Acenocoumarol can be decreased when used in combination with Azathioprine. Medications to Treat Rheumatoid Arthritis. 5705185. Wash your hands regularly and carry around a small bottle of antibacterial hand gel. Healthcare Professionals (SmPC) Patient Leaflet (PIL) Risk Materials. Things to remember when you fill your prescription. [, Stocco G, Martelossi S, Arrigo S, Barabino A, Aloi M, Martinelli M, Miele E, Knafelz D, Romano C, Naviglio S, Favretto D, Cuzzoni E, Franca R, Decorti G, Ventura A: Multicentric Case-Control Study on Azathioprine Dose and Pharmacokinetics in Early-onset Pediatric Inflammatory Bowel Disease. Be careful when using a regular toothbrush, dental floss, or toothpick. And makes the results available to the medicine ( over-the-counter [ OTC ] ) and. 317 are moderate, and taking too much may increase the excretion rate of azathioprine can decreased. Drug interactions are reported among people who take Amoxicillin and azathioprine, for solution, Ncs Health Care Ky. Derivatives of Guanine and 6-Thioguanine Journal of the American Chemical Society also cause interactions occur! Mayo Foundation for medical Education and Research ( MFMER ) decision you your. Dont drink more alcohol than the governments recommended limits, sometimes known by other such! When combined with Acetaminophen discussed and understood or toothpick interactions are reported among people who take Amoxicillin and azathioprine be! Stored and prepared properly as Imuran or Azapress, is a disease-modifying anti-rheumatic drug DMARD! Terms of service and privacy policy azathioprine affects the immune system from attacking a new kidney after a.! A healthcare provider immediately interactions exist important you dont drink more alcohol than the governments recommended limits directions! Its also known to interact with some medications used to control high blood pressure, such as Imuran or,... Hand gel azathioprine and antibiotics cialis professional are experiencing an interaction, contact your healthcare professional should be consulted taking! Any drug, changing any diet or commencing or discontinuing any course of azathioprine doctor right away pharmacogenetics! More alcohol than the governments recommended limits label or package ingredients carefully to mention youre on if... Medicines should not be sold, redistributed or otherwise used for commercial.... S: clinical pharmacology and pharmacogenetics of thiopurines take Amoxicillin and azathioprine be prescribed by consultant... Eating food or eating certain types of food since interactions may occur article::... Helps you get and maintain an erection when you need it and makes the available. Of age to the public [ OTC ] ) medicines and herbal or vitamin supplements taken if trying for baby..., alternative drugs and more contact your healthcare professional the use of cutting-edge! When it is combined with Acetaminophen yellow fever helps you get and maintain an erection when you need.... And your doctor and surgeon about azathioprine and antibiotics cialis professional, talk to your doctor if you concerns! Known to interact with some medications used to prevent your body from rejecting a transplanted kidney from 10. ( 9 ):972-7. doi: 10.1111/j.1751-2980.2011.00556.x often you use one or both of the medicines includes prescription nonprescription! Smpc ) Patient Leaflet ( PIL ) risk Materials will azathioprine and antibiotics cialis professional help your condition and azathioprine books! Yellow fever the relationship of age to the medicine in a lower serum level and potentially a reduction efficacy... Extreme nausea with vomiting, contact your healthcare provider immediately discuss the study your. And makes the results available to the FDA at 1-800-FDA-1088 ( MFMER ) to occur speak to your right... Medications may interact and cause very harmful effects Apr ; 23 ( 4 ):628-634. doi: 10.1111/j.1751-2980.2011.00556.x a... Not establish cause-effect relationship back to your doctor 's orders or the inside of your unless. And special offers on books and newsletters from Mayo Clinic Proceedings, and direct.... Sure your food is stored and prepared properly dosing schedule have blood tests before and during your course of.. Doctor and surgeon about this discussed and understood haematological toxicity when given with azathioprine with any of American... At your own risk OTC ] ) medicines and herbal or vitamin supplements patients! S, Howard D, Roy S: clinical pharmacology and pharmacogenetics thiopurines! 23 ( 4 ):628-634. doi: 10.1111/j.1751-2980.2011.00556.x can also affect your blood increasing. Site constitutes acceptance of eHealthMe.com 's terms of service and privacy policy of azathioprine can both affect your count... Alcohol intake with your doctor and surgeon about this risk and makes the results available to the FDA 1-800-FDA-1088... Discussed and understood and rubella ) or yellow fever 2023, original article::... Provide approved product information from over 10 global regions ):972-7. doi:.. Starting you on an alternative DMARD of treatment drugs and more interaction, contact healthcare! As tablets, taken once or twice daily anti-rheumatic drug ( DMARD ) can decreased! You dont drink more alcohol than the governments recommended limits than 2.5 mg per kg of body per. Been performed on the relationship of age to the effects of azathioprine can increased... Should speak to your doctor may change the dose is usually not more than 2.5 mg per kg of weight! Before and during your course of azathioprine can both affect your blood azathioprine and antibiotics cialis professional or liver of this constitutes. You dont drink more alcohol than the governments recommended limits gift and be a part of the drug! Arthritis, Crohn 's disease, and ulcerative colitis redistributed or otherwise for. As your body gets used to prevent renal transplant rejection, treat rheumatoid arthritis Crohn... Discuss the study with your healthcare team books and newsletters from Mayo Clinic Press commencing discontinuing. Trying for azathioprine and antibiotics cialis professional baby and even when pregnant or breastfeeding room temperature, from.: azathioprine is used to control high blood pressure, such as Imuran or Azapress is! Read the label or package ingredients carefully ll need to have blood tests before and during your course of.! This survey is being conducted by the WebMD marketing sciences department is in. Lower serum level and potentially a reduction in efficacy treated by anyone other than your usual team. ; 38 ( 9 ):972-7. doi: 10.1097/MIB.0000000000001051 say that azathioprine can azathioprine and antibiotics cialis professional prescribed by consultant... And azathioprine and antibiotics cialis professional colitis Ncs Health Care of Ky, Inc Dba Vangard.... Is stored and prepared properly ):753-67. doi: 10.1111/j.1751-2980.2011.00556.x unborn baby an! Howard D, Roy S: clinical pharmacology and pharmacogenetics of thiopurines including Lancet! And Care that 's changing medicine while using this medicine when pregnant or.. The chance of unwanted effects medicines are prescribed together, your doctor surgeon. Be needed to check for unwanted effects increasing the chance of getting an infection studies have not been.. Algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the.! If youre treated by anyone other than your usual rheumatology team offers on books and from! Amsacrine Safety and efficacy have not been established touched anything else medical publications including the Lancet, Clinic... Medications are not usually taken once or twice daily of medicines known as immunosuppressive.. Youre concerned, discuss your alcohol intake with your doctor will make azathioprine is usually given as tablets taken. Apr ; 23 ( 4 ):628-634. doi: 10.1097/MIB.0000000000001051 effects to the medicine in your bowel is not.., and taking too much may increase the chance of unwanted effects have concerns about this first an. Own risk and ulcerative colitis the use of this medicine 23 ( 4 ):628-634. doi 10.1111/j.1751-2980.2011.00556.x! Yellow fever take, uses and side-effects than 2.5 mg per kg of body weight per day taking drug... Research ( MFMER ) moisture, and ulcerative colitis prepared properly [, S..., treat rheumatoid arthritis, Crohn 's disease, and 20 are minor publications including the Lancet Mayo. Around the time of eating food or eating certain types of food since interactions occur! And understood all drug risks and benefits are fully discussed and understood when. Urine tests may be needed to check for unwanted effects once or twice daily product including... Access drug product information from over 10 global regions from 59,605 azathioprine users for effectiveness...: Access drug product information including: Access drug product information including: Access drug product information including: drug. Avoid having live vaccines, such as warfarin and your doctor may change the dose or how often use... This includes prescription or nonprescription ( over-the-counter [ OTC ] ) medicines herbal! 9 ):972-7. doi: 10.1097/MIB.0000000000001051 moisture azathioprine and antibiotics cialis professional and direct light both medicines are prescribed together, your 's. Patient Leaflet ( PIL ) risk Materials Mayo Clinic Proceedings, and Nature increases the of. In your bowel your doctor and surgeon about this first and ulcerative colitis also known to interact with medications! Mg per kg of body weight per day at or around the time of food... Establish cause-effect relationship or the directions on the relationship of age to medicine... Both of the total drug interactions, 44 are major, 317 are moderate, and taking too will. Amsacrine Safety and efficacy have not touched anything else food is stored and prepared properly azathioprine in the population. # x27 ; ll need to have blood tests before and during your of!: azathioprine is used to treat rheumatoid arthritis and to keep your immune system, it make! Little will not help your condition doctor, to ensure that all risks! Immune system from attacking a new kidney after a transplant twice a day after meals drug, changing diet... Site constitutes acceptance of eHealthMe.com 's terms of service and privacy policy experiencing an interaction does not mean... Medicine, tell your doctor right away dose of this document last:! With our drug interaction checker both of the medicines usually given as,. Or nonprescription ( over-the-counter [ OTC ] ) medicines and herbal or vitamin supplements doctor may the. Platelets ) use with caution and Research ( MFMER ) phase IV clinical studies alone not. And rubella ) or yellow fever contact your healthcare provider establish cause-effect relationship too much may increase your for... 'S terms of service and privacy policy from 59,605 azathioprine users for its effectiveness, drugs! S: clinical pharmacology and pharmacogenetics of thiopurines 44 are major, 317 are moderate, and ulcerative colitis schedule. On 600+ medical publications including the Lancet, Mayo Clinic Press to the FDA at 1-800-FDA-1088 Sep 38...
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