Usual dose: 0.63 to 2.5 mg inhaled by nebulizer 3 to 4 times daily. Cisapride: (Contraindicated) QT prolongation and ventricular arrhythmias, including torsade de pointes (TdP) and death, have been reported with cisapride. Monitor the patient's lung and cardiovascular status closely. Concomitant use may potentiate sympathetic effects. Beta-agonists can sometimes increase heart rate or have other cardiovascular effects, particularly when used in high doses or if hypokalemia is present. 0.15 mg/kg/dose enterally every 8 hours for 96 hours improved pulmonary resistance in ventilator-dependent premature neonates at risk for developing chronic lung disease (n = 30). Methylxanthine derivatives, ((e.g., theophylline and aminophylline) may rarely aggravate the hypokalemic effect seen with beta-agonists. Children aged 12 years and over: dose as per adult population. The World Health Organization recommended name for albuterol base is salbutamol. Monitor the patient's lung and cardiovascular status closely. Prime VENTOLIN HFA before using for the first time, when the inhaler has not been used for more than 2 weeks, or when the inhaler has been dropped. Ibuprofen; Pseudoephedrine: (Moderate) Monitor blood pressure and heart rate during concomitant albuterol and pseudoephedrine use. No significant differences in FEV1 have been demonstrated between metered-dose inhalers (with or without a spacer) and nebulizers for SABAs in clinical trials; nebulizers may be more convenient for patients who are more acutely ill.[63765], 2.5 mg inhaled by nebulizer every 6 to 8 hours as needed. Onset of action begins within 30 minutes, peak levels are reached in 2 to 3 hours, and duration of action is 4 to 6 hours for the conventional-release tablets and 8 to 12 hours for the sustained-release product. Beta-agonists and beta-blockers are pharmacologic opposites and will counteract each other to some extent when given concomitantly, especially when non-cardioselective beta blockers are used. Print patient leaflet in large text. being unable to get an erection at any time. Use of a beta-1-selective (cardioselective) beta blocker is recommended whenever possible when this combination of drugs must be used together. Brompheniramine; Pseudoephedrine: (Moderate) Monitor blood pressure and heart rate during concomitant albuterol and pseudoephedrine use. Green Tea: (Moderate) Some green tea products contain caffeine, which is a CNS-stimulant. H 2 SO 4. Monitor the patient's lung and cardiovascular status closely. Discard albuterol inhaler when the counter reads 000 or 12 months after it is taken out of the foil pouch, whichever comes first. When the dose counter reads 020, you should refill your prescription or ask your doctor if you need another prescription. Use albuterol with caution in patients with diabetes mellitus. If an adequate response is not obtained, dose may be increased gradually with caution. Mechanism of Action: Albuterol is a moderately selective beta2-adrenergic agonist that stimulates receptors of the smooth muscle in the lungs, uterus, and vasculature supplying skeletal muscle. If an adequate response is not obtained, dose may be increased gradually with caution. Monitor the patient's lung and cardiovascular status closely. Acebutolol: (Moderate) Beta-blockers will block the pulmonary effects of inhaled beta-agonists, and in some cases may exacerbate bronchospasm in patients with reactive airways. Common Ventolin side effects may include: Administration via nebulization does not appear to significantly alter the pharmacokinetics of albuterol. The systemic exposure in children 6 to 11 years of age is similar to that of adults after 180 mcg single dose oral inhalation. Beta-agonists and beta-blockers are pharmacologic opposites and will counteract each other to some extent when given concomitantly, especially when non-cardioselective beta blockers are used. The inhaler provides about 200 inhalations. Max: 24 mg/day. Monoamine oxidase inhibitors: (Moderate) Use beta-agonists with caution in patients receiving concomitant monoamine oxidase inhibitors (MAOIs) or within 14 days of stopping treatment with MAOIs because the action of beta-agonists on the cardiovascular system may be potentiated. Right after the spray comes out, release the canister. Guidelines recommend against the use of oral short-acting beta-2 agonists (SABAs) due to the slow onset of action and increased risk for side effects. Use inhaled SABAs for acute bronchospasm; do not use oral agents. Concomitant use may potentiate sympathetic effects. VENTOLIN HFA has a counter attached to the canister. The dose counter only displays even numbers (example: 200, 198, 196, etc.) 2 to 4 mg PO 3 to 4 times daily. Thyroid hormones may increase the risk of coronary insufficiency when sympathomimetic agents are administered to patients with coronary artery disease. The patient should hold their breath for about 10 seconds or as long as they comfortably can.Remove the inhaler from the mouth.Check the dose counter on the back of the inhaler to make sure the dose was received.Close the cap over the mouthpiece after each use of the inhaler; make sure the cap closes firmly into place.To inhale another dose, close the cap and then repeat inhaler steps.The inhaler contains a powder and must be kept clean and dry at all times. Bendroflumethiazide; Nadolol: (Moderate) Beta-blockers will block the pulmonary effects of inhaled beta-agonists, and in some cases may exacerbate bronchospasm in patients with reactive airways. Beta-agonists can sometimes increase heart rate or have other cardiovascular effects, particularly when used in high doses or if hypokalemia is present. Acetaminophen; Guaifenesin; Phenylephrine: (Moderate) Caution and close observation should be used when albuterol is used concurrently with other adrenergic sympathomimetics, administered by any route, to avoid potential for increased cardiovascular effects. 4 CONTRAINDICATIONS 33 VENTOLIN HFA is contraindicated in patients with a history of hypersensitivity to any 34 of the ingredients [56384]Powder for Inhalation (e.g., ProAir RespiClick, ProAir Digihaler)Instruct patient on proper inhalation technique; see the specific product's "Instructions for Use" from the manufacturer.Before using for the first time, check the dose counter window to ensure that the inhaler is full and the number "200" is in the window. Phenylephrine: (Moderate) Caution and close observation should be used when albuterol is used concurrently with other adrenergic sympathomimetics, administered by any route, to avoid potential for increased cardiovascular effects. DOSE CONVERSION: 2 mg immediate-release PO every 6 hours = 4 mg extended-release PO every 12 hours. Concomitant use may potentiate sympathetic effects. [49951] Other products should be discarded when the labeled number of actuations has been used or by the expiration date printed on original packaging; whichever comes first. Codeine; Guaifenesin; Pseudoephedrine: (Moderate) Monitor blood pressure and heart rate during concomitant albuterol and pseudoephedrine use. Phentermine: (Moderate) Monitor blood pressure and heart rate during concomitant albuterol and phentermine use. Levothyroxine; Liothyronine (Porcine): (Moderate) Monitor blood pressure and heart rate during concomitant beta-agonist and thyroid hormone use. Monitor the patient's lung and cardiovascular status closely. Esmolol: (Moderate) Beta-blockers will block the pulmonary effects of inhaled beta-agonists, and in some cases may exacerbate bronchospasm in patients with reactive airways. If an adequate response is not obtained, dose may be increased gradually with caution. Albuterol can produce a clinically significant cardiovascular effect in some patients as measured by increases in pulse rate, systolic or diastolic blood pressure, and cardiac arrhythmias, such as supraventricular tachycardia and extrasystoles. being able to get an erection, but not having it last long enough for sex. Use of a beta-1-selective (cardioselective) beta blocker is recommended whenever possible when this combination of drugs must be used together. The elimination half-life of albuterol ranges from 2.7 to 6 hours, with orally administered albuterol having a shorter half-life than the inhaled product. Levobunolol: (Moderate) Beta-blockers will block the pulmonary effects of inhaled beta-agonists, and in some cases may exacerbate bronchospasm in patients with reactive airways. Repeat inhaler steps. Use of a beta-1-selective (cardioselective) beta blocker is recommended whenever possible when this combination of drugs must be used together. Albuterol is an effective adjunctive treatment for hyperkalemia; beta2-adrenergic stimulation results in intracellular accumulation of serum potassium due to stimulation of the Na/K ATPase pump, leading to moderate degrees of hypokalemia. Beta-agonists can sometimes increase heart rate or have other cardiovascular effects, particularly when used in high doses or if hypokalemia is present. Higher maximum dosages for inhalation products have been recommended in NAEPP guidelines for acute exacerbations of asthma.1 year: Safety and efficacy have not been established; nebulizer inhalation maximum dependent on patient response and formulation used. Thyroid hormones may increase the risk of coronary insufficiency when sympathomimetic agents are administered to patients with coronary artery disease. After oral administration, 75% of a dose is excreted in urine within 72 hours as metabolites; 4% may be found in feces. Guaifenesin; Pseudoephedrine: (Moderate) Monitor blood pressure and heart rate during concomitant albuterol and pseudoephedrine use. Prevention of exercise-induced asthma: The recommended dose is 2 puffs 15 to 30 minutes before exercise. Beta-agonists and beta-blockers are pharmacologic opposites and will counteract each other to some extent when given concomitantly, especially when non-cardioselective beta blockers are used. Serum potassium concentrations must be closely monitored during the treatment of DKA and albuterol may contribute to changes in serum potassium concentrations. 180 mcg (2 actuations of 90 mcg/actuation) inhaled by mouth 15 to 30 minutes before exercise. [31823][49951][59350]. Beta-agonists can sometimes increase heart rate or have other cardiovascular effects, particularly when used in high doses or if hypokalemia is present. Fluctuations in plasma concentrations are similar for albuterol extended-release tablets administered at 12-hour intervals and immediate-release tablets administered at 6-hour intervals. Typical dosing for albuterol (Ventolin) Asthma: The typical dosing of albuterol (Ventolin) is 1 to 2 puffs by mouth every 4 to 6 hours when needed for wheezing or shortness of breath. DOSE CONVERSION: 2 mg immediate-release PO every 6 hours = 4 mg extended-release PO every 12 hours. Concomitant use may potentiate sympathetic effects. 2.5 mg inhaled by nebulizer every 20 minutes for the first hour for mild to moderate exacerbations, then 2.5 mg every 3 to 4 hours and up to 2.5 mg every 1 to 2 hours, or more often. Displays even numbers ( example: 200, 198, 196, etc. years. 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