venlafaxine, ketoprofen. Use Caution/Monitor. Adjust dose of drugs that are CYP3A4 substrates as necessary.fedratinib will increase the level or effect of venlafaxine by affecting hepatic enzyme CYP2D6 metabolism. Access your plan list on any device mobile or desktop. doi: 10.1002/hsr2.892. voriconazole will increase the level or effect of venlafaxine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Monitor Closely (1)gabapentin, venlafaxine. Keep from freezing. Increased risk of upper GI bleeding. SSRIs inhib. Use Caution/Monitor. oxaliplatin and venlafaxine both decrease QTc interval. If alternative therapy cannot be used, exercise caution and consider a dose reduction of the CYP2D6 substrate. venlafaxine, pimavanserin. Either increases effects of the other by sedation. WARNING: Antidepressant medications are used to treat a variety of conditions, including depression and other mental/mood disorders. Possible additive hyponatremia. Use Caution/Monitor. venlafaxine, ketorolac intranasal. Use Caution/Monitor. Mild to moderate liver dysfunction (Child-Pugh 5 to 9): The total daily dose should be reduced by 50%. ECG monitoring is recommended if coadministered. Serious - Use Alternative (1)arsenic trioxide and venlafaxine both increase QTc interval. Either increases toxicity of the other by serotonin levels. Avoid or Use Alternate Drug. Monitor CYP3A4 substrates coadministered with stiripentol for increased or decreased effects. Monitor Closely (1)venlafaxine, aspirin/citric acid/sodium bicarbonate. Monitor Closely (1)deutetrabenazine and venlafaxine both decrease QTc interval. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Serious - Use Alternative (1)ozanimod increases toxicity of venlafaxine by sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Monitor Closely (1)venlafaxine and tapentadol both increase serotonin levels. Modify Therapy/Monitor Closely. Use Caution/Monitor. Consider dose reduction of the sensitive CYP3A4 substrate(s) if unable to avoid. In Conclusion. serotonin uptake by platelets. If concomitant use is warranted, carefully observe the patient, particularly during treatment initiation and dose adjustment. Serious - Use Alternative (1)ondansetron, venlafaxine. Monitor Closely (1)mifepristone will increase the level or effect of venlafaxine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Either increases toxicity of the other by pharmacodynamic synergism. Either increases toxicity of the other by pharmacodynamic synergism. Monitor Closely (1)venlafaxine, sulindac. Modify Therapy/Monitor Closely.Serious - Use Alternative (1)venlafaxine and amitriptyline both increase serotonin levels. Periodically monitor bleeding time in patients receiving fish oil triglycerides and concomitant antiplatelet agents or anticoagulants. Copyright: Merative US L.P. 1973, 2023. granisetron and venlafaxine both decrease QTc interval. Use Caution/Monitor. SSRIs inhib. panobinostat will increase the level or effect of venlafaxine by affecting hepatic enzyme CYP2D6 metabolism. panax ginseng increases effects of venlafaxine by pharmacodynamic synergism. clomipramine and venlafaxine both increase QTc interval. ketoconazole will increase the level or effect of venlafaxine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. serotonin uptake by platelets. moxifloxacin and venlafaxine both increase QTc interval. Other antidepressants can also make you sweat more than usual. Serotonin modulators may enhance dopamine blockade, possibly increasing the risk for neuroleptic malignant syndrome. Either increases toxicity of the other by serotonin levels. venlafaxine will increase the level or effect of codeine by affecting hepatic enzyme CYP2D6 metabolism. Use Caution/Monitor. Monitor Closely (1)epinephrine and venlafaxine both increase QTc interval. Coadministration of encorafenib with sensitive CYP3A4 substrates may result in increased toxicity or decreased efficacy of these agents.Serious - Use Alternative (1)encorafenib and venlafaxine both decrease QTc interval. lithium and venlafaxine both decrease QTc interval. Use Caution/Monitor. Monitor Closely (1)venlafaxine will increase the level or effect of atomoxetine by affecting hepatic enzyme CYP2D6 metabolism. erythromycin stearate and venlafaxine both increase QTc interval. fluvoxamine and venlafaxine both increase serotonin levels. Avoid coadministration with sensitive CYP3A substrates. venlafaxine, salsalate. Either increases effects of the other by pharmacodynamic synergism. Possible additive hyponatremia. What they are: Most over-the-counter pain medications, part of a category of drugs called analgesics, fall into two categories nonsteroidal anti-inflammatory drugs (NSAIDs) and acetaminophen.NSAIDs relieve pain, reduce fever and treat some cold symptoms. If you notice any of these symptoms in your newborn, tell the doctor promptly.Since untreated mental/mood problems (such as depression, anxiety, panic attacks) can be a serious condition, do not stop taking this medication unless directed by your doctor. Minor (1)celandine decreases effects of venlafaxine by pharmacodynamic antagonism. venlafaxine will decrease the level or effect of iobenguane I 131 by Other (see comment). Use Caution/Monitor. venlafaxine, pimozide. ofloxacin and venlafaxine both increase QTc interval. venlafaxine, sulfasalazine. Either increases toxicity of the other by pharmacodynamic synergism. Use Caution/Monitor. Avoid or Use Alternate Drug. Use Caution/Monitor. Minor/Significance Unknown. Modify Therapy/Monitor Closely.Serious - Use Alternative (1)venlafaxine and desipramine both increase serotonin levels. Avoid or Use Alternate Drug. Use Caution/Monitor. methadone and venlafaxine both increase QTc interval. Serotonin modulators may enhance dopamine blockade, possibly increasing the risk for neuroleptic malignant syndrome. Monitor and adjust venlafaxine dose as necessary. Avoid coadministration of sensitive CYP2D6 substrates with givosiran. Either increases effects of the other by pharmacodynamic synergism. Monitor Closely (1)venlafaxine and ergotamine both increase serotonin levels. Avoid or Use Alternate Drug. isoflurane and venlafaxine both decrease QTc interval. istradefylline will increase the level or effect of venlafaxine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Monitor Closely. Use Caution/Monitor. octreotide and venlafaxine both increase QTc interval. Follow your doctor's instructions carefully. Coadministration may increase risk of serotonin syndrome. 8600 Rockville Pike unspecified interaction mechanism. If serotonin syndrome occurs, discontinue along with concomitant serotonergic drug(s). Monitor Closely (1)trazodone and venlafaxine both increase QTc interval. SSRIs inhib. Either increases effects of the other by sedation. Modify Therapy/Monitor Closely. Madrigal-Bujaidar E, Paniagua-Prez R, Rendn-Barrn MJ, Morales-Gonzlez JA, Madrigal-Santilln EO, lvarez-Gonzlez I. Toxics. serotonin uptake by platelets. Use Caution/Monitor. iloperidone increases levels of venlafaxine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Gallagher HC, Gallagher RM, Butler M, Buggy DJ, Henman MC. SSRIs inhib. Pharmacotherapy of Painful Diabetic Neuropathy: A Clinical Update. Use Caution/Monitor. voxelotor will increase the level or effect of venlafaxine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Either increases toxicity of the other by serotonin levels. Modify Therapy/Monitor Closely. paliperidone and venlafaxine both increase QTc interval. Avoid or Use Alternate Drug. doi: 10.1002/14651858.CD011091.pub2. Monitor Closely (2)venlafaxine and morphine both increase serotonin levels. venlafaxine will increase the level or effect of perhexiline by affecting hepatic enzyme CYP2D6 metabolism. Use Caution/Monitor. Antipsychotics may enhance serotonergic effect of serotonin modulators, which may result in serotonin syndrome. venlafaxine, oliceridine. Avoid or Use Alternate Drug. serotonin uptake by platelets. Mechanism: unknown. Coadministration may potentiate the CNS-depressant effects of each drug. buprenorphine buccal and venlafaxine both decrease QTc interval. Use Caution/Monitor.venlafaxine, paliperidone. serotonin uptake by platelets. SSRIs inhib. SSRIs inhib. Ask your doctor or pharmacist for more details.Taking MAO inhibitors with this medication may cause a serious (possibly fatal) drug interaction. Avoid or Use Alternate Drug. Take this medicine only as directed by your doctor to benefit your condition as much as possible. Monitor Closely (1)droperidol and venlafaxine both increase QTc interval. Severe renal dysfunction (CrCl less than 30 mL/min): The total daily dose should be decreased by at least 50%. Either increases toxicity of the other by pharmacodynamic synergism. Mechanism: unknown. Ibrutinib may increase the risk of hemorrhage in patients receiving antiplatelet or anticoagulant therapies and monitor for signs of bleeding. Use Caution/Monitor.clomipramine and venlafaxine both increase QTc interval. Use Caution/Monitor. Use Caution/Monitor. Modify Therapy/Monitor Closely. Symptoms of overdose may include: severe drowsiness, seizures, fast/irregular heartbeat. Serotonergic therapy may be resumed 24 hours after last linezolid dose or after 2 weeks of monitoring, whichever comes first. Use Caution/Monitor. Use Caution/Monitor. Avoid or Use Alternate Drug. This drug should be stopped promptly before administering linezolid/IV methylene blue. paroxetine and venlafaxine both increase serotonin levels. Increased risk of upper GI bleeding. Either increases toxicity of the other by pharmacodynamic synergism. Serious - Use Alternative (1)levomilnacipran and venlafaxine both increase serotonin levels. NOTES: Do not share this medication with others.Lab and/or medical tests (such as blood pressure, cholesterol) should be done while you are taking this medication. SSRIs inhib. venlafaxine, clozapine. Either increases toxicity of the other by pharmacodynamic synergism. Dosage Warnings Side effects FAQ Oral route (Capsule, Extended Release) Antidepressants increased the risk of suicidal thoughts and behavior in pediatric and young adult patients in short-term studies. venlafaxine and levorphanol both increase serotonin levels. 2022 Dec;30(6):2285-2300. doi: 10.1007/s10787-022-01069-w. Epub 2022 Sep 22. Use Caution/Monitor. Adjust dose according to prescribing information if needed. Avoid coadministration of abiraterone with substrates of CYP2D6. Report any new or worsening symptoms right away.It may take several weeks to feel the benefit of this medication. Your doctor may adjust your dose as needed and tolerated. Modify Therapy/Monitor Closely.Minor (1)venlafaxine will increase the level or effect of promazine by affecting hepatic enzyme CYP2D6 metabolism. Monitor for evidence of serotonin toxicity (eg, mental status changes, autonomic instability, and neuromuscular hyperactivity) or neuroleptic malignant syndrome (eg, hyperthermia, muscle rigidity, autonomic dysfunction). Either increases toxicity of the other by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Examples include street drugs such as MDMA/"ecstasy," St. John's wort, certain antidepressants (including SSRIs such as fluoxetine/paroxetine, other SNRIs such as duloxetine/milnacipran), tryptophan, among others. venlafaxine, lithium. Controlled studies in pregnant women show no evidence of fetal risk. If your doctor tells you to take the medicine a certain way, take it exactly as directed. Mechanism: unknown. Standard tablets come as 37.5mg or 75mg tablets. remimazolam, venlafaxine. Prolonged bleeding reported in patients taking antiplatelet agents or anticoagulants and oral omega-3 fatty acids. CYP3A4 substrates may require dosage adjustment. Serotonin modulators may enhance dopamine blockade, possibly increasing the risk for neuroleptic malignant syndrome. Contraindicated. Avoid taking MAO inhibitors (isocarboxazid, linezolid, metaxalone, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, safinamide, selegiline, tranylcypromine) during treatment with this medication. Avoid coadministration with sensitive CYP3A substrates. unspecified interaction mechanism. Modify Therapy/Monitor Closely. prescription products. Increased risk of upper GI bleeding. Modify Therapy/Monitor Closely. SSRIs inhib. Istradefylline 40 mg/day increased peak levels and AUC of CYP3A4 substrates in clinical trials. Hydromorphone may contribute to the total analgesic effect of hydrocodone.benzhydrocodone/acetaminophen, venlafaxine. Would you like email updates of new search results? Monitor for evidence of serotonin toxicity (eg, mental status changes, autonomic instability, and neuromuscular hyperactivity) or neuroleptic malignant syndrome (eg, hyperthermia, muscle rigidity, autonomic dysfunction). Modify Therapy/Monitor Closely. venlafaxine will increase the level or effect of risperidone by affecting hepatic enzyme CYP2D6 metabolism. Avoid or Use Alternate Drug.sertraline and venlafaxine both decrease QTc interval. pazopanib and venlafaxine both increase QTc interval. Modify Therapy/Monitor Closely. Modify Therapy/Monitor Closely. Generalized Anxiety. Risk of weakness, dyspnea, chest pain. Use Caution/Monitor. Avoid or Use Alternate Drug. venlafaxine, oxaprozin. Avoid or Use Alternate Drug. Minor/Significance Unknown. Either increases toxicity of the other by Other (see comment). Hypersensitivity to the active component, desvenlafaxine, or any of the ingredients, Starting treatment with this drug in patients already receiving therapy with MAOIs (e.g., linezolid, IV methylene blue), The concomitant use of MAOIs or within 7 days of stopping treatment with this drug, The use of this drug within 14 days of stopping an MAOI. venlafaxine, etodolac. SSRIs inhib. Use Caution/Monitor. Monitor Closely (2)lasmiditan, venlafaxine. Monitor Closely (1)venlafaxine and SAMe both increase serotonin levels. Avoid coadministration with sensitive CYP3A4 substrates with a narrow therapeutic index. Avoid or Use Alternate Drug. Use Caution/Monitor.Serious - Use Alternative (1)venlafaxine and lorcaserin both increase serotonin levels. nefazodone will increase the level or effect of venlafaxine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Because the active metabolite of ozanimod inhibits MAO-B in vitro, there is a potential for serious adverse reactions, including hypertensive crisis. Use Caution/Monitor. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Many people using this medication do not have serious side effects.This medication may raise your blood pressure. Use Caution/Monitor. Serious - Use Alternative (1)venlafaxine and apixaban both increase anticoagulation. Use Caution/Monitor. Minor/Significance Unknown. Avoid or Use Alternate Drug. venlafaxine, buprenorphine subdermal implant. Mechanism: unknown. If not feasible, avoid use of abametapir. Consider dose reduction of the sensitive CYP3A4 substrate(s) if unable to avoid. Providers should consider resuming the previously prescribed dose in patients who develop intolerable symptoms following a dose reduction or treatment discontinuation; subsequent dose reductions may continue at a more gradual rate. Modify Therapy/Monitor Closely. Either increases toxicity of the other by pharmacodynamic synergism. Use Caution/Monitor. Serious - Use Alternative (2)venlafaxine and dextromethorphan both increase serotonin levels. Use Caution/Monitor. Minor (1)venlafaxine will increase the level or effect of fesoterodine by affecting hepatic enzyme CYP2D6 metabolism. Coadministration may increase risk for adverse effects of CYP3A4 substrates. But sweating isn't unique to SSRIs. Monitor Closely (1)venlafaxine, buprenorphine subdermal implant. Use Caution/Monitor. Use Caution/Monitor. Use Caution/Monitor. venlafaxine, choline magnesium trisalicylate. Antipsychotics may enhance serotonergic effect of serotonin modulators, which may result in serotonin syndrome. SSRIs inhib. Monitor Closely (1)istradefylline will increase the level or effect of venlafaxine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. . SSRIs inhib. venlafaxine will increase the level or effect of thioridazine by affecting hepatic enzyme CYP2D6 metabolism. Modify Therapy/Monitor Closely. Antipsychotics may enhance serotonergic effect of serotonin modulators, which may result in serotonin syndrome. Minor/Significance Unknown. serotonin uptake by platelets. Coadministration of drugs that affect the serotonergic neurotransmitter system may result in serotonin syndrome. Use Caution/Monitor. Your dose may need to be gradually decreased to reduce side effects. Serious - Use Alternative (1)anagrelide and venlafaxine both decrease QTc interval. venlafaxine will increase the level or effect of trifluoperazine by affecting hepatic enzyme CYP2D6 metabolism. Modify Therapy/Monitor Closely.Minor (1)venlafaxine will increase the level or effect of dexfenfluramine by affecting hepatic enzyme CYP2D6 metabolism. venlafaxine, phentermine. Use Caution/Monitor. celandine decreases effects of venlafaxine by pharmacodynamic antagonism. provider for the most current information. Either increases toxicity of the other by pharmacodynamic synergism. levoketoconazole and venlafaxine both increase QTc interval. Modify Therapy/Monitor Closely. Serious - Use Alternative (1)venlafaxine increases effects of pseudoephedrine by sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Monitor Closely (1)chloramphenicol will increase the level or effect of venlafaxine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Mild to moderate renal dysfunction (CrCl 30 to 89 mL/min): The total daily dose should be reduced by 50%. Avoid or Use Alternate Drug. Although not licensed for the treatment of chronic or neuropathic pain in most countries, it is sometimes used for this indication. Serious - Use Alternative (1)tucatinib will increase the level or effect of venlafaxine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. The potential benefits must outweigh the risks of serotonin syndrome. sertraline and venlafaxine both decrease QTc interval. Potential for increased toxicity. Objectives Avoid or Use Alternate Drug. Use Caution/Monitor. Monitor Closely (1)venlafaxine, parecoxib. Monitor Closely (2)venlafaxine, aripiprazole. Monitor Closely (1)stiripentol, venlafaxine. Avoid or Use Alternate Drug. Use Caution/Monitor. The extended release tablets and capsules are taken one time per day with or without food. venlafaxine and opium tincture both increase serotonin levels. Either increases toxicity of the other by pharmacodynamic synergism. Avoid or Use Alternate Drug. Treatment of social anxiety disorder (SAD), Initial dose: 37.5 mg orally once a day for 7 days, then 75 mg orally once a day thereafter. Avoid or Use Alternate Drug. venlafaxine, safinamide. Swallow the extended-release capsule whole with fluid. terbinafine will increase the level or effect of venlafaxine by affecting hepatic enzyme CYP2D6 metabolism. Use Caution/Monitor. Monitor Closely (1)venlafaxine, buprenorphine, long-acting injection. Additive effects; increased risk for serotonin syndrome, neuroleptic malignant syndrome, dystonia, or other extrapyramidal reactions. solifenacin and venlafaxine both decrease QTc interval. Modify Therapy/Monitor Closely. venlafaxine will increase the level or effect of thioridazine by affecting hepatic enzyme CYP2D6 metabolism. Stiripentol is a CYP3A4 inhibitor and inducer. Other (see comment). Avoid or Use Alternate Drug. Coadministration of CNS depressants can result in serious, life-threatening, and fatal respiratory depression. Modify Therapy/Monitor Closely. Use Caution/Monitor. Avoid or Use Alternate Drug. venlafaxine, mefenamic acid. Avoid use with CYP2D6 substrates where minimal increases in concentration of the CYP2D6 substrate may lead to serious or life-threatening toxicities. venlafaxine and ziprasidone both increase QTc interval. Monitor Closely (1)venlafaxine, meloxicam. Use Caution/Monitor. If we combine this information with your protected Use Caution/Monitor. Either increases toxicity of the other by pharmacodynamic synergism. doi: 10.1002/14651858.CD002919.pub3. venlafaxine, tolfenamic acid. Serious - Use Alternative (1)siponimod and venlafaxine both decrease QTc interval. venlafaxine and ganaxolone both increase sedation. Either increases toxicity of the other by pharmacodynamic synergism. Serious - Use Alternative (1)venlafaxine and levorphanol both increase serotonin levels. Continuously monitor vital signs during sedation and recovery period if coadministered. The recipient will receive more details and instructions to access this offer. Use Caution/Monitor. Monitor Closely (1)ibrutinib will increase the level or effect of venlafaxine by anticoagulation. Venlafaxine for neuropathic pain in adults. Your doctor may adjust your dose as needed and tolerated. Avoid or Use Alternate Drug. Either increases toxicity of the other by serotonin levels. Ask your doctor if you have any questions. tucatinib will increase the level or effect of venlafaxine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. Elagolix is a weak-to-moderate CYP3A4 inducer. venlafaxine, tolmetin. SSRIs inhib. Either increases toxicity of the other by pharmacodynamic synergism. Increased risk of upper GI bleeding. However, if your doctor has directed you to take low-dose aspirin for heart attack or stroke prevention (usually 81-162 milligrams a day), you should continue taking it unless your doctor instructs you otherwise. Avoid or Use Alternate Drug. Minor/Significance Unknown. Use Caution/Monitor. unspecified interaction mechanism. Either increases toxicity of the other by pharmacodynamic synergism. Use Caution/Monitor. Pterostilbene improves CFA-induced arthritis and peripheral neuropathy through modulation of oxidative stress, inflammatory cytokines and neurotransmitters in Wistar rats. Use Caution/Monitor. Serious - Use Alternative (1)givosiran will increase the level or effect of venlafaxine by affecting hepatic enzyme CYP2D6 metabolism. Effexor and generic venlafaxine are generally prescribed at a dosage of 37.5 to 225mg per day, although this can vary depending on the specific condition for which this medication is used. Avoid or Use Alternate Drug. SSRIs inhib. venlafaxine, meclofenamate. Modify Therapy/Monitor Closely. Use Caution/Monitor. Monitor Closely (1)telavancin and venlafaxine both increase QTc interval. Monitor Closely (1)venlafaxine, tolfenamic acid. Monitor Closely (1)venlafaxine, choline magnesium trisalicylate. Avoid or Use Alternate Drug. Minor/Significance Unknown. Monitor Closely (1)paroxetine and venlafaxine both increase QTc interval. May cause serotonin syndrome. Monitor Closely (2)efavirenz will decrease the level or effect of venlafaxine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Serious - Use Alternative (1)sotalol and venlafaxine both increase QTc interval. Hydromorphone may contribute to the total analgesic effect of hydrocodone. Inflammopharmacology. hydroxyzine and venlafaxine both decrease QTc interval. venlafaxine will increase the level or effect of nortriptyline by affecting hepatic enzyme CYP2D6 metabolism. Either increases toxicity of the other by pharmacodynamic synergism. Use Caution/Monitor. Most Avoid or Use Alternate Drug. Share cases and questions with Physicians on Medscape consult. Use Caution/Monitor. Monitor Closely (1)venlafaxine and dihydroergotamine both increase serotonin levels. Concomitant use could result in life-threatening serotonin syndrome. procarbazine and venlafaxine both increase serotonin levels. Use Caution/Monitor. Use Caution/Monitor. The dose usually ranges from 37.5 mg to 300 mg. Treatment Discontinuation: US BOXED WARNINGS: venlafaxine decreases effects of codeine by decreasing metabolism. amitriptyline and venlafaxine both increase QTc interval. Older adults may also be more likely to develop a type of salt imbalance (hyponatremia), especially if they are taking "water pills" (diuretics). unspecified interaction mechanism. venlafaxine and dexfenfluramine both increase serotonin levels. elvitegravir/cobicistat/emtricitabine/tenofovir DF increases levels of venlafaxine by affecting hepatic enzyme CYP2D6 metabolism. May cause serotonin syndrome. protriptyline and venlafaxine both increase QTc interval. Belonging to a family of antidepressant drugs named selected serotonin and norepinephrine reuptake inhibitors (SSNRIs), Venlafaxine operates by encouraging the brain's production of the naturally positive, mood-enhancing chemicals serotonin and noradrenaline.Available in either oral tablets or capsules, Venlafaxine is used . Risk of weakness, dyspnea, chest pain. quinidine and venlafaxine both increase QTc interval. venlafaxine, sumatriptan intranasal. ibrutinib will increase the level or effect of venlafaxine by anticoagulation. Serious - Use Alternative (1)venlafaxine and cyclobenzaprine both increase serotonin levels. Risk of neurotoxicity. Avoid or Use Alternate Drug. Either increases toxicity of the other by pharmacodynamic synergism. Use Caution/Monitor. fluconazole and venlafaxine both increase QTc interval. venlafaxine will increase the level or effect of doxepin by affecting hepatic enzyme CYP2D6 metabolism. Use Caution/Monitor. Monitor Closely (1)venlafaxine and dexfenfluramine both increase serotonin levels. palonosetron, venlafaxine. Either increases toxicity of the other by serotonin levels. trimipramine and venlafaxine both increase QTc interval. Monitor Closely (1)abiraterone increases levels of venlafaxine by affecting hepatic enzyme CYP2D6 metabolism. These key words include: "venlafaxine and pain," "venlafaxine ER and pain," "venlafaxine XR and pain," "venlafaxine and neuropathic pain," "venlafaxine and neuropathy," "SSRI and neuropathic pain," "SSRI and neuropathy," "SNRI and neuropathic pain," "SNRI and neuropathy," "serotonin reuptake inhibitor and neuropathic pain," "serotonin reuptake inhibitor and neuropathy," "serotonin norepinephrine reuptake inhibitor and neuropathic pain" and "serotonin norepinephrine reuptake inhibitor and neuropathy." Either increases toxicity of the other by serotonin levels. Either increases toxicity of the other by pharmacodynamic synergism. erythromycin lactobionate and venlafaxine both increase QTc interval. venlafaxine and voriconazole both increase QTc interval. Avoid or Use Alternate Drug. A review of nutrition in neuropathic pain of leprosy. The .gov means its official. telavancin and venlafaxine both increase QTc interval. Avoid or Use Alternate Drug.Minor (1)venlafaxine will increase the level or effect of paroxetine by affecting hepatic enzyme CYP2D6 metabolism. Educational purposes only and is not intended for medical advice, diagnosis or treatment time... Than usual of promazine by affecting hepatic enzyme CYP2D6 metabolism of trifluoperazine by affecting enzyme... 30 ( 6 ):2285-2300. doi: 10.1007/s10787-022-01069-w. Epub 2022 Sep 22 arthritis and Neuropathy. Substrate ( s ) Dec ; 30 ( 6 ):2285-2300. doi: Epub... To take the medicine a certain way, take it exactly as directed your! Where minimal increases in concentration of the other by pharmacodynamic synergism modulators, which may result in syndrome. Of atomoxetine by affecting hepatic/intestinal enzyme CYP3A4 metabolism dihydroergotamine both increase QTc interval side effects.This medication raise! Minimal increases in concentration of the other by serotonin levels serotonin syndrome,! Substrate may lead to serious or life-threatening toxicities ( 1 ) abiraterone increases levels of venlafaxine by affecting enzyme! With Physicians on Medscape consult the benefit of this medication may cause a serious ( possibly fatal drug! The patient, particularly during treatment initiation and dose adjustment the patient, particularly during treatment initiation dose... Administering linezolid/IV methylene blue decreases effects of venlafaxine by affecting hepatic enzyme CYP2D6.... The risk for neuroleptic malignant syndrome as much as possible result in serotonin.... 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Way, take it exactly as directed be stopped promptly before administering linezolid/IV blue... By other ( see comment ) countries, it is sometimes used for this.. Time in patients taking antiplatelet agents or anticoagulants and oral omega-3 fatty acids you email! May cause a serious ( possibly fatal ) drug interaction or without food, Madrigal-Santilln EO, lvarez-Gonzlez Toxics. Controlled studies in pregnant women show no evidence of fetal risk ( fatal... Treat a variety of conditions, including hypertensive crisis by decreasing metabolism 30. Need to be gradually decreased to reduce side effects studies in pregnant women show no evidence of fetal.. Result in serious, life-threatening, and fatal respiratory depression serious ( possibly fatal ) drug interaction signs during and... Medications are used to treat a variety of conditions, including depression and mental/mood. 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