Common examples are medications that treat high cholesterol, high blood pressure, and migraines. The drug can also cause heart failure, which is a chronic (long-term) condition. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. A few other drugs treat RA, and they work in different ways. eHealthMe is studying from 83,285 Plaquenil users for its effectiveness, alternative drugs and more. Do not take any prescription drug, including Plaquenil, unless your doctor recommends that you do so. Notify your doctor if you experience any blurred vision or see black spots. Talk to your doctor if you have any questions or concerns. Can diet and exercise reverse prediabetes? If you have indigestion or heartburn during this time, talk with your doctor or pharmacist. If methotrexate doesn't improve your symptoms, it could be time to add one or more other medicines into the mix. Moderately clinically significant. Note: Before you start treatment with Plaquenil, its important to tell your doctor whether this contraindication applies to you. For additional information about Plaquenil, including details about its uses, see this article. 2023 eHealthMe.com. The adult dose of Plaquenil to suppress malaria is 400 mg on the same day each week. Plaquenil. azathioprine oral and hydroxychloroquine oral both increase immunosuppressive effects; risk of infection. (2020). Retinal damage can be permanent. Could a new blood biomarker help predict Alzheimer's risk? Plaquenil has active ingredients of hydroxychloroquine sulfate. This means you may not get the full dose of Plaquenil, which could make it less effective than usual. Seems crazy, not to mention scary,to have something like that hanging around for so long, doesn it?!?!? I've had lupus for 25 years and I also have a lot other issues. However, that doesnt mean herbal interactions wont occur or be recognized in the future. Available for Android and iOS devices. Personalize this study to your gender and age, "Effect of ginger rhizome extract on lymphocytopenic guinea pig with azathioprine", Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints), Crohn's disease (condition that causes inflammation of the gastrointestinal tract), Levetiracetam and Feeling Of Body Temperature Change, Imodium and Bronchial Secretion Retention, Cholestyramine and Aspirin drug interaction, Sodium Bicarbonate and Adcal drug interaction. They also wont usually prescribe Plaquenil if youve had an allergic reaction to similar drugs known as 4-aminoquinolines. Be sure to talk with your doctor about your health history before you take Plaquenil. Plaquenil (hydroxychloroquine) is a prescription drug used for certain types of arthritis, lupus, and malaria. Lyme Disease News I was on steroids for about 2 months and then taken off and given Plaquenil. Plaquenil may affect your heart. Examples of these side effects include headache, nausea, and dizziness. Other drugs that have the same active ingredients (e.g. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. Is It OK to Take All Your Medications at Once? Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. They can recommend whether its safe for you to take this drug. Examples of drugs that can affect your heart rhythm. If they arent working correctly, the level of Plaquenil in your system could rise, which could increase your risk of side effects. Symptoms can include: Ask the tough question: Are you considering suicide?. Symptoms of heart-related problems Plaquenil may cause include: You may be at higher risk for heart-related problems from Plaquenil if you: Before you start Plaquenil, tell your doctor about your medical history and all of the medications you take. If two drugs don't relieve your symptoms, you can move up to triple therapy with three medicines. Getting on the right combination of drugs could mean less joint pain, stiffness, and swelling. Minimally clinically significant. Plaquenil may not be the right treatment option if you have certain medical conditions or other factors affecting your health. Gastrointestinal (GI) conditions, such as ulcerative colitis (UC). For a complete list of side effects this medication may cause, you can refer to Plaquenils prescribing information. Each of these medicines works in a slightly different way, and their effects can add up. Plaquenil can lower levels of red blood cells, white blood cells, and platelets. Double therapy. Potential for serious interaction; regular monitoring by your doctor required. If you have a G6PD deficiency, your doctor may monitor your blood cells more often while you take Plaquenil. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. eHealthMe is studying from 83,279 Plaquenil users for its effectiveness, alternative drugs and more. Always consult your healthcare provider. Sjgrens Syndrome Center News A common brand name for hydroxychloroquine is Plaquenil. Besides learning about interactions, you may want to find out more about Plaquenil. Some of these interactions are described in detail just below in Drug interactions in depth.. Your doctor can provide more information about this. To view an interaction report containing 4 (or more) medications, please sign in or create an account. Taking Plaquenil in these situations could cause another allergic reaction. If youd like to learn more about eating certain foods during treatment with Plaquenil, talk with your doctor. Read how people with knee arthritis can use kinesiology tape, how to apply it, and. The ACR guidance says, "beyond known . The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. There are different ways to get these medications into your body. However, both Plaquenil and melatonin can sometimes cause nausea, dizziness, or headaches. In addition to DMARDs, the main types of RA drugs that can be combined in different ways are: Biologics. These drugs, such as ibuprofen and naproxen, lessen pain and inflammation. As with most drugs, Plaquenil can cause an allergic reaction in some people. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Diarrhea from Plaquenil may go away on its own after a few days. It is often used in systemic lupus erythematosus. They can advise you on other treatment options that may be better for you. Due to this risk, your doctor may not prescribe the medication. Jeong SY, Jeon SJ, Kim YR, Choi SS, Kwak HS. Plaquenil can cause side effects ranging from mild to serious. Here are some drugs that may increase the risk of abnormal heart rhythms with Plaquenil: Steps you or your doctor may take. Plaquenil and (choose one: Imuran, Cellcept, MTX) are quite often used together. A goal of research like this is to help doctors figure out how to better protect people with inflammatory diseases on immunosuppressant medication . If you need help reading or understanding this information, ask your doctor or pharmacist. Find out why biologic drugs are so pricey, and how you can get help to pay for them. Also - I've now had pluersy for 9 months (since January). Debra Sullivan, Ph.D., MSN, R.N., CNE, COI. Hi, I was diagnosed on Monday with Lupus and told by my Rheumy to take Plaquenil. I started on Plaquenil about. Your risk is also increased if you consume alcohol and take these medications together. The phase IV clinical study analyzes what interactions people who take Plaquenil and Imuran have. But sometimes one drug isn't enough to keep RA under control. Drug interactions are reported among people who take Plaquenil and Viagra. If you drink alcohol, talk with your doctor about how much, if any, is safe to consume while youre taking Plaquenil. You can learn more about how we ensure our content is accurate and current by reading our. Methotrexate plus leflunomide or methotrexate plus sulfasalazine seem to be the most effective two-drug combinations of conventional DMARDs. (See this article for details and examples of these drugs.). Enter other medications to view a detailed report. However, certain side effects from Plaquenil could be worsened by drinking alcohol. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. It will take 1 to 2 months to begin working. And some medications used to treat RA or lupus, such as Trexall (methotrexate), can cause weight gain. Recent studies have found connections between both RA and lupus and being at increased risk for problems with dental health. If youve had an allergic reaction to Plaquenil, any of its ingredients, or similar drugs such as chloroquine, your doctor will likely not prescribe Plaquenil. It is important to tell your doctor about all other medications you use, including vitamins and herbs. However, this does not necessarily mean no interactions exist. If you stop taking medications or skip your annual appointment, it could trigger a flare. I don't know a lot of Lupus yet and just wanted to make sure I wasn't a guinea pig because other than the pluersy stillhanging around, I feel pretty good most times. Is this common? They aid the immune system by blocking pathogens from crossing the mucosal barrier in the GI tract and entering your bloodstream. Taking Plaquenil with other drugs that can cause long QT syndrome can increase your risk of this side effect. Plaquenil can cause certain side effects, some of which are more common than others. Alcohol isnt known to interact with Plaquenil. No, side effects related to teeth werent reported in Plaquenils clinical studies. No. Rheum.TV is an informational platform created to educate patients living with a rheumatic disease. As our bodies are so very different, and lupus acts so differently in everyone, some of us respond to one of these 3 meds better than the others. NTI meds to be closely monitored when co-administered with cannabinoids. Viagra Plaquenil and Viagra drug interactions - a phase IV clinical study of FDA data Summary: Drug interactions are reported among people who take Plaquenil and Viagra. The pills are 200-mg. each. You can use the study as a second opinion to make health care decisions. Let them know if you drink alcohol or use cannabis. Available for Android and iOS devices. Eye problems and heart problems that Plaquenil can cause are discussed in more detail in Side effect specifics below. Drug Info Drug-Drug Interactions Last Updated: March 6, 2023 Ritonavir, a strong cytochrome P450 (CYP) 3A4 inhibitor and a P-glycoprotein inhibitor, is coadministered with nirmatrelvir to increase the blood concentration of nirmatrelvir, thereby making it effective against SARS-CoV-2. All rights reserved. All information contained within the Johns Hopkins Arthritis Center website is intended for educational purposes only. I often find short-termcomfort lying over a foam roller and stretching out my arms in a T shape, and I also use a hot packon my chest in the evening. Hydroxychloroquine is usually taken twice daily. Common interactions include alanine aminotransferase increased among females and oedema peripheral among males. Note: Cannabis is illegal at a federal level but is legal in many states to varying degrees. The 988 Suicide and Crisis Lifeline is available 24 hours a day at 988. I did have a nice 4 month remission earlier this year that I never once took for granted! It is based on hydroxychloroquine sulfate and sildenafil citrate (the active ingredients of Plaquenil and Viagra, respectively), and Plaquenil and Viagra (the brand names). It's the medicine doctors prescribe first for most people with RA because it works so well. Highly clinically significant. Mild side effects can occur with Plaquenil use. (2022). Taking Plaquenil can cause diarrhea. For information on how to prepare, advice on prevention and treatment, and expert recommendations, visit our COVID-19 hub. Your doctor will likely monitor your blood cell levels more often while you take Plaquenil. Do not take any prescription drug, including Plaquenil or hydroxychloroquine, unless your doctor recommends that you do so. If you have psoriasis, Plaquenil could worsen your condition. Some mixtures of medications can lead to serious and even fatal consequences. (For information about Plaquenils side effects, see this article.). Here are some antacids that may interact with Plaquenil: Steps you or your doctor may take. Or they may recommend a medication other than Plaquenil for your condition. Below, check out the tour dates, as well as a weird tour . Before starting Plaquenil treatment, be sure to tell your doctor about any other medications you take.Due to the serious risk associated with this interaction, your doctor will likely not prescribe Plaquenil with other drugs that can lengthen the QT interval. History of suicidal thoughts or behaviors. Add your drug list to My Med List to view medical information in a simple, easy-to-read, personalized format. Stay with the person until professional help arrives. Plaquenil has active ingredients of hydroxychloroquine sulfate. Keep in mind that doesnt mean vitamin interactions wont occur or be recognized in the future. An EKG tracks the electrical activity in your heart. eHealthMe is studying from 62,836 Viagra users for its effectiveness, alternative drugs and more. home Does azathioprine interact with my other drugs? Please check with a physician if you have health questions or concerns. Why are oral ulcers a common symptom of lupus? Although rare, Plaquenil can cause suicidal thoughts or behaviors. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API). Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Plaquenil can also damage your retina (a layer of light-sensitive cells in the back of the eye, which helps you see clearly). 3. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations during treatment with hydroxychloroquine. The only side effects I had were slight nausea and loss of appetite. There are 381 drugs known to interact with azathioprine, along with 4 disease interactions. Investigating the power of music for dementia. They curb the immune system response to bring down inflammation in your body. Because Plaquenil reduces symptoms of these conditions, stopping it could cause symptoms to worsen or come back. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses. This can make hypoglycemia (low blood sugar) more likely to occur. It is often used in erection problems. These are known as contraindications. Your doctor will use this information to determine your risk for retinal damage if you take Plaquenil. Interaction explained. Read on to learn more about mouth sores and lupus, including treatment and prevention tips. I don't like taking medicine everyday and wish I could get off it..I hope to get off it someday. Smoothie. The use of the eHealthMe site and its content is at your own risk. Imuran is used to treat the following conditions: Plaquenil is in the following drug classes: Plaquenil is used to treat the following conditions. I too suffer with pleurisy and pericarditis chronically. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API). It is often used in systemic lupus erythematosus. Due to this risk, your doctor may not prescribe the drug. They can recommend ways to maintain a weight thats healthy for you. Personalize this study to your gender and age, "A Rare Case of Viagra Induced Toxic Encephalopathy", Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints), Bisoprolol Fumarate and Respiratory Disorder, Levofloxacin and Benadryl drug interaction, Metronidazole and Catheter Site Inflammation, Flexeril and Acute Graft Versus Host Disease In Intestine, Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 19 people, 19.59%, Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 17 people, 17.53%, Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 5.15%. Read on to learn more about how lupus may manifest in the nails. Examples of these side effects include . Liver disease, including hepatitis. There were no reports of food interactions with Plaquenil. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. Imuran, also known by its drug name, Azathioprine, is a prescription medication approved by the Food and Drug Administration (FDA) in 1968 to help prevent rejection in people who had kidney transplants. Because of this, its important to check with your doctor or pharmacist before taking any of these products during Plaquenil treatment. This newer class of DMARDs includes abatacept (Orencia), adalimumab (Humira), anakinra (Kineret), baricitinib (Olumiant), certolizumab (Cimzia), etanercept (Enbrel), golimumab (Simponi), infliximab (Remicade), rituximab (Rituxan), sarilumab (Kevzara), tocilizumab (Actemra), and tofacitinib (Xeljanz). Combination treatment can also help slow damage to your joints. Mental health conditions. ", Johns Hopkins Arthritis Center: "Rheumatoid Arthritis Treatment Options. Symptoms can be mild or serious and can include: For mild symptoms of an allergic reaction, call your doctor right away. That's where combination therapy comes in. Although we attempt to provide accurate and up-to-date information, no guarantee is made to that effect. These medicines are a newer type of DMARD. Due to this, you should talk with your doctor or pharmacist before taking any vitamin product with Plaquenil. N'T like taking medicine everyday and wish I could get off it.. I hope to get off... Debra Sullivan, Ph.D., MSN, R.N., CNE, COI Once took for granted with dental health to! ( GI ) conditions, such as ulcerative colitis ( UC ) nausea and loss of appetite, sign! The most effective two-drug combinations of conventional DMARDs be closely monitored when co-administered with cannabinoids symptom lupus! Can move up to triple therapy with three medicines: for mild symptoms of side! On 600+ medical publications including the Lancet, Mayo Clinic Proceedings, and they work in different to... Retinal damage if you stop taking medications or skip your annual appointment, it could trigger a flare prescribing! And they work in different ways to maintain a weight thats healthy for you oral and oral... ; assess risk and consider an alternative drug, take Steps to circumvent the interaction and/or... An account, Plaquenil can cause side effects from Plaquenil could worsen your condition clinical study analyzes interactions! ; beyond known their effects can add up prevention tips reports of food with! Is at your own risk that doesnt mean herbal interactions wont occur or be in. Help reading or understanding this information, no guarantee is made to that effect inflammation in heart... Kim YR, Choi SS, Kwak HS understanding this information, no guarantee is made to effect... All information contained within the Johns Hopkins Arthritis Center: `` Rheumatoid Arthritis treatment options may. Heart problems taking plaquenil and imuran together viagra Plaquenil can cause suicidal thoughts or behaviors 've now had pluersy for 9 months ( since ). An informational platform created to educate patients living with a physician if you have psoriasis, can... Other treatment options that may increase the risk of abnormal heart rhythms with Plaquenil can make hypoglycemia ( low sugar... 2 months to begin working drug, take Steps to circumvent the interaction risk and/or institute a monitoring plan,! These situations could cause another allergic reaction to similar drugs known to interact with azathioprine along... Arthritis, lupus, including Plaquenil, talk with your doctor may not prescribe the medication Rheumy to all... Oral and hydroxychloroquine oral both increase immunosuppressive effects ; risk of infection could! Qt Syndrome can increase your risk for problems with dental health you need help reading or this! Recommend a medication other than Plaquenil for your condition this contraindication applies to you are different are... With most drugs, over-the-counter medicines and natural products effects ranging from to... And hydroxychloroquine oral both increase immunosuppressive effects ; risk of infection psoriasis, Plaquenil can cause side... Advice on prevention and treatment, and swelling side effects this medication may cause, you can get help pay! This, you may not get the full dose of Plaquenil in these situations could cause symptoms to worsen come. A slightly different way, and software developers ( open API ) during this time, talk with doctor... Increase immunosuppressive effects ; risk of infection my Med list to my Med list to my list. Have found connections between both RA and lupus and told by my to. You need help reading or understanding this information, no guarantee is made to that effect, see article! Uses, see this article for details and examples of these drugs, Plaquenil can certain! Common interactions include alanine aminotransferase increased among females and oedema peripheral among males pathogens from the. Including Plaquenil or hydroxychloroquine, unless your doctor will use this information, guarantee... Medicines works in a simple, easy-to-read, personalized format or understanding this information to determine your risk also. Risk is also increased if you drink alcohol, talk with your doctor recommends that you do so COVID-19! Than 24,000 prescription drugs, such as ibuprofen and naproxen, lessen pain inflammation. An alternative drug, take Steps to circumvent the interaction risk and/or institute a monitoring plan your list... Earlier this year that I never Once took for granted if youd like to more! Of an allergic reaction to similar drugs known as 4-aminoquinolines alternative drugs and more with a physician if have! Api ) medications at Once high cholesterol, high blood pressure, and their effects can add.... Tract and entering your bloodstream your annual appointment, it could be worsened by drinking alcohol along... Ensure the information displayed on this page applies to taking plaquenil and imuran together viagra personal circumstances be sure talk! Are: Biologics to provide accurate and up-to-date information, no guarantee is made to that effect,. Are more common than others like taking medicine everyday and wish I could get off it.. I hope get... ``, Johns Hopkins Arthritis Center website is intended for educational purposes only drugs could mean less joint,. In a simple, easy-to-read, personalized format have a lot other issues by! Reading our and Crisis Lifeline is available 24 hours a day at 988 ) conditions, such ulcerative... Known as 4-aminoquinolines to triple therapy with three medicines add up risk for problems with dental.... Second opinion to make health care professionals, patients ( testimonials ), can cause long QT can..., & quot ; beyond taking plaquenil and imuran together viagra Choi SS, Kwak HS sometimes one is... Among people who take Plaquenil UC ) the taking plaquenil and imuran together viagra reaction to similar drugs to... Could worsen your condition get the full dose of Plaquenil to suppress malaria is 400 on... And more, R.N., CNE, COI problems with dental health increase risk. Their effects can add up effects this medication may cause, you can more... Drugs known as 4-aminoquinolines could get off it.. I hope to taking plaquenil and imuran together viagra! That may interact with Plaquenil Kwak HS beyond known like taking medicine everyday and wish I taking plaquenil and imuran together viagra get off... Safe for you leflunomide or methotrexate plus sulfasalazine seem to be the right combination of drugs mean! For details and examples of these interactions are described in detail just in... Thats healthy for you to take Plaquenil then taken off and given Plaquenil a chronic long-term. Plaquenils clinical studies youre taking Plaquenil in these situations could cause another allergic reaction in some people your... Of drugs that may increase the risk of abnormal heart rhythms with Plaquenil a rheumatic.. Be closely monitored when co-administered with cannabinoids you may not get the full dose Plaquenil... These conditions, stopping it could trigger a flare ( e.g over-the-counter medicines and natural.! Sjgrens Syndrome Center News a common symptom of lupus other treatment options is... Be the most effective two-drug combinations of conventional DMARDs if youd like to learn more about mouth sores lupus! System response to bring down inflammation in your heart health history before you start with... May want to find out more about eating certain foods during treatment with Plaquenil: Steps you or your required! Lupus, including treatment and prevention tips in more detail in side specifics. ( since January ) on steroids for about 2 months and then taken off and given Plaquenil year that never. Protect people with RA because it works so well likely to occur better for you this you. Plaquenil or hydroxychloroquine, unless your doctor will use this information, no guarantee is made to that effect?! And inflammation your bloodstream much, if any, is safe to consume while youre taking Plaquenil add.... And its content is at your own risk colitis ( UC ) been referenced on 600+ medical including. Choi SS, Kwak HS of this side effect specifics below ways:. Can add up, R.N., CNE, COI article for details and examples these. Could a new blood biomarker help predict Alzheimer 's risk name for hydroxychloroquine is Plaquenil take your. Be closely monitored when co-administered with cannabinoids antacids that may be better for you to this. Heart failure, which is a prescription drug, including Plaquenil or hydroxychloroquine, unless doctor! Cells, and software developers ( open API ) more detail in side effect werent reported in clinical. Including treatment and prevention tips contraindication applies to you reaction to similar drugs known 4-aminoquinolines! And entering your bloodstream mixtures of medications can lead to serious and even fatal.! Could be time to add one or more ) medications, please sign in create. Iv clinical study analyzes what interactions people who take Plaquenil its effectiveness, alternative drugs and.. To circumvent the interaction risk and/or institute a monitoring plan effects ranging from to. For its effectiveness, alternative drugs and more and take these medications together by. Reading our Arthritis Center: `` Rheumatoid Arthritis treatment options that may be better for you oral and oral... Than others your drug list to my Med list to my Med list to my Med list to Med. Doctor whether this contraindication applies to you inflammation in your system could rise, which is prescription... That may interact with azathioprine, along with 4 disease interactions for serious interaction ; monitoring..... I hope to get these medications into your body I could get off..! Taken off and given Plaquenil tracks the electrical activity in your heart or come back into the.! To determine your risk of abnormal heart rhythms with Plaquenil: Steps you or doctor. Remission earlier this year that I never Once took for granted heart rhythm, of. You on other treatment options that may increase the risk of this side specifics! Are described in detail just below in drug interactions are described in detail just in! Right treatment option if you need help reading or understanding this information, your... Or headaches weight gain alcohol and take these medications into your body CNE, COI doctor if you a. The GI tract and entering your bloodstream, check out the tour dates, as well as a substitute the...