Philipp T, Smith TR, Glazer R, Wernsing M, Yen J, Jin J, Schneider H, Pospiech R. Clin Ther. Monitor Closely (1)hydralazine, phendimetrazine. Controlled studies in pregnant women show no evidence of fetal risk. prescription products. Use Caution/Monitor. According to the American College of Allergy, Asthma, and Immunology, medication allergies may not develop the first time you take a drug. Use Caution/Monitor. Use Caution/Monitor. National Library of Medicines list Use Caution/Monitor. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Use Caution/Monitor. Use Caution/Monitor. Minor/Significance Unknown. Monitor Closely (1)hydralazine increases effects of metoprolol by pharmacodynamic synergism. Use Caution/Monitor. Mechanism: pharmacodynamic antagonism. A ten-week, double-blind, parallel-treatment phase followed in which patients were randomly assigned to the combination tablet or to propranolol or hydralazine. maitake increases effects of hydralazine by pharmacodynamic synergism. Serious - Use Alternative (1)lofexidine, hydralazine. Monitor Closely (1)hydralazine increases effects of propranolol by pharmacodynamic synergism. Monitor Closely (1)hydralazine increases effects of atenolol by pharmacodynamic synergism. Either increases effects of the other by pharmacodynamic synergism. Use Caution/Monitor. Direct vasodilator; dilates arterioles with little effect on vein; decreases systemic resistance, which subsequently decreases blood pressure. NSAIDs decrease prostaglandin synthesis. Use Caution/Monitor. Monitor Closely (1)celecoxib decreases effects of hydralazine by pharmacodynamic antagonism. Risk of hypertension. piroxicam decreases effects of hydralazine by pharmacodynamic antagonism. "What's important is to [consistently] take metoprolol the same way," Dr. Cooke adds. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis. NSAIDs decrease prostaglandin synthesis. Use Caution/Monitor. This site needs JavaScript to work properly. levodopa increases effects of hydralazine by pharmacodynamic synergism. Monitor Closely (2)hydralazine increases effects of carvedilol by pharmacodynamic synergism. Avoid driving or operating hazardous machinery until you know how these medications affect you, and use caution when getting up from a sitting or lying position. Use Caution/Monitor. Check for more interactions with the Drug Interaction Checker, Never use this combination of drugs because of high risk for dangerous interaction, Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed, Potential for significant interaction (monitoring by your doctor is likely required), Interaction is unlikely, minor, or nonsignificant. Minor/Significance Unknown. Risk of hypertension. Use Caution/Monitor. Pexidartinib can cause hepatotoxicity. People who take multiple medications. Mechanism: pharmacodynamic synergism. Use of this site constitutes acceptance of eHealthMe.com's terms of service and privacy policy. After a three-week, single-blind, placebo period, a 9- to 18-week, single-blind, dose-finding phase with . carvedilol increases effects of hydralazine by pharmacodynamic synergism. NSAIDs decrease prostaglandin synthesis. Use Caution/Monitor. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis. . No warnings were found for your selected drugs. ketoprofen decreases effects of hydralazine by pharmacodynamic antagonism. Nearly half of U.S. adults have some form of heart disease, according to the American Heart Association's latest statistical update, published in March 2019 in Circulation .The medication metoprolol (Lopressor, Toprol, Toprol XL) is one of the drugs commonly prescribed to treat heart-related concerns, according to the U.S. National Library of Medicine, including: Use Caution/Monitor. Your doctor may recommend a vitamin B6 supplement (pyridoxine).Tell your doctor right away if you have any serious side effects, including: severe tiredness, aching/swollen joints, rash on nose and cheeks, swollen glands, signs of kidney problems (such as change in the amount of urine, bloody/pink urine), signs of infection (such as sore throat that doesn't go away, fever, chills), easy bruising/bleeding.Get medical help right away if you have any very serious side effects, including: chest/jaw/left arm pain.A very serious allergic reaction to this drug is rare. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis. Compare formulary status to other drugs in the same class. Monitor Closely (1)tolmetin decreases effects of hydralazine by pharmacodynamic antagonism. Mechanism: pharmacodynamic synergism. Add your drug list to My Med List to view medical information in a simple, easy-to-read, personalized format. Use Caution/Monitor. Additive hypotensive effects. Monitor when coadministered with weak CYP3A4 inhibitors . To view formulary information first create a list of plans. Additive hypotensive effects. Please check with a physician if you have health questions or concerns. Read more: What People With Heart Disease and Diabetes Need to Know About Their COVID-19 Risk. hydralazine, methylenedioxymethamphetamine. Mechanism: pharmacodynamic synergism. Either increases effects of the other by pharmacodynamic synergism. etodolac decreases effects of hydralazine by pharmacodynamic antagonism. Coadministration of mild CYP3A4 inhibitors with midazolam intranasal may cause higher midazolam systemic exposure, which may prolong sedation. These include the possibility of allergic reaction or negative interaction with other medications as well as the way certain health conditions may affect the medication. RxList does not provide medical advice, diagnosis or treatment. hydralazine, diethylpropion. Use Caution/Monitor. Allergy symptoms, which generally appear within hours, but may appear later, include: If you experience serious issues after taking metoprolol, such as difficulty breathing, call 911. Mechanism: pharmacodynamic synergism. Avoid combinations; the risk of the interaction outweighs the benefit. Copyright(c) 2023 First Databank, Inc. Additive hypotensive effects. Sympathomimetics can antagonize the activity of some antihypertensive agents. NSAIDs decrease prostaglandin synthesis. Summary: Drug interactions are reported among people who take Metoprolol succinate and Hydralazine hydrochloride. hydralazine, procarbazine. Use Caution/Monitor. Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. Use Caution/Monitor. See additional information. Mechanism: pharmacodynamic antagonism. Use Caution/Monitor. This drug is available at a higher level co-pay. All rights reserved. hydralazine, ephedrine. HydroCHLOROthiazide may add to the blood pressure lowering effects of hydrALAZINE. All information is observation-only. Comment: Pretomanid regimen associated with hepatotoxicity. Use Caution/Monitor. Some heart medications may interact negatively with grapefruit or foods high in potassium or protein. Use Caution/Monitor. Metoprolol (Oral Route) Side Effects - Mayo Clinic Drugs and Supplements Metoprolol (Oral Route) Description and Brand Names Drug information provided by: IBM Micromedex US Brand Name Lopressor Toprol XL Descriptions Metoprolol is used alone or together with other medicines to treat high blood pressure (hypertension). Additive hypotensive effects. Monitor Closely (1)hydralazine, procarbazine. Bethesda, MD 20894, Web Policies Use Caution/Monitor. It works by relaxing the blood vessels so that blood can flow more easily through the body. NSAIDs decrease prostaglandin synthesis. Epinephrine When amifostine is used at chemotherapeutic doses, withhold blood pressure lowering medications for 24 hr prior to amifostine; if blood pressure lowering medication cannot be withheld, do not administer amifostine. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. Additive hypotensive effects. Modify Therapy/Monitor Closely. Monitor Closely (1)piroxicam decreases effects of hydralazine by pharmacodynamic antagonism. Minor/Significance Unknown. Monitor Closely (1)hydralazine, xylometazoline. Sympathomimetics can antagonize the activity of some antihypertensive agents. Sympathomimetics can antagonize the activity of some antihypertensive agents. Access your plan list on any device mobile or desktop. Highly clinically significant. Mechanism: pharmacodynamic antagonism. Serious - Use Alternative (1)hydralazine, pretomanid. NSAIDs decrease prostaglandin synthesis. The National Library of Medicine suggests talking to your doctor if you have certain conditions that could affect metoprolol or make it inappropriate for you. Monitor Closely (1)flurbiprofen decreases effects of hydralazine by pharmacodynamic antagonism. Either increases effects of the other by pharmacodynamic synergism. aceclofenac decreases effects of hydralazine by pharmacodynamic antagonism. reishi increases effects of hydralazine by pharmacodynamic synergism. Risk of hypertension. Monitor Closely (1)amifostine, hydralazine. shepherd's purse, hydralazine. NSAIDs decrease prostaglandin synthesis. Risk of hypotension. Some people are more at risk for problems when mixing alcohol with blood pressure medications, including: People over 65 years old. Use Caution/Monitor. Use Caution/Monitor. You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood. Use Caution/Monitor. problems, such as a slow heart rate, serious circulation issue or heart failure. Minor (1)hydralazine will increase the level or effect of ruxolitinib topical by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. Mechanism: pharmacodynamic synergism. To help you remember, take it at the same times each day. Copyright 2023 by RxList Inc. An Internet Brands company. Minor/Significance Unknown. Mechanism: pharmacodynamic synergism. Use Caution/Monitor. Additive hypotensive effects. Use Caution/Monitor. metoprolol succinate oral brand names and other generic formulations include: hydralazine oral increases effects of metoprolol succinate oral by added drug effects. Monitor Closely (1)hydralazine increases effects of acebutolol by pharmacodynamic synergism. Mechanism: pharmacodynamic synergism. hydralazine, midodrine. Use Caution/Monitor. Use Caution/Monitor. US residents can call their local poison control center at 1-800-222-1222. Risk of hypertension. hydralazine will increase the level or effect of atogepant by affecting hepatic/intestinal enzyme CYP3A4 metabolism. commonly, these are "non-preferred" brand drugs. Modify Therapy/Monitor Closely. Sign in to your account to save this drug interaction list. After a three-week, single-blind, placebo period, a 9- to 18-week, single-blind, dose-finding phase with the combination was performed. 2010bidil-isosorbide-dinitrate-hydralazine-342277Drugs, 2010hydra-zide-hydralazine-hydrochlorothiazide-999426Drugs, encoded search term (hydralazine ((hydralazine))) and hydralazine ((hydralazine)), Nuanced Management of Heart Failure With Reduced Ejection Fraction (HFrEF): Select Patients, Case Challenge: Woman Presents to Emergency Department With Headache and Hypertension, Updated Heart Failure Guidelines: Time for a Refresh, Medscape Cardiologist Wealth & Debt Report 2021. Minor/Significance Unknown. Monitor Closely (1)tadalafil increases effects of hydralazine by pharmacodynamic synergism. Minor (1)cornsilk increases effects of hydralazine by pharmacodynamic synergism. Minor/Significance Unknown. Monitor Closely (1)hydralazine increases levels of ivacaftor by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Sympathomimetics can antagonize the activity of some antihypertensive agents. Monitor Closely (1)ketoprofen decreases effects of hydralazine by pharmacodynamic antagonism. NSAIDs decrease prostaglandin synthesis. Will increase the level or effect of atogepant by affecting hepatic/intestinal enzyme CYP3A4 metabolism you,. Provide taking metoprolol and hydralazine together levitra advice, diagnosis or treatment including: People over 65 old! Remember, take steps to circumvent the interaction risk and/or institute a plan! Evidence of fetal risk taking metoprolol and hydralazine together levitra effects of the other by pharmacodynamic antagonism can call Their poison... 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