Opioids work by attaching to opioid receptors, which are found in many areas of the body, including the brain, spinal cord and gastrointestinal tract. The more common side effects of bulk-forming laxatives are bloating or abdominal pain. However, bulk-forming laxatives also come in a number of other forms, such as: All forms of bulk-forming laxatives should be taken with plenty of water or other liquid. Understanding the differences between laxatives and stool softeners may help a person decide which one to use. Make your tax-deductible gift and be a part of the cutting-edge research and care that's changing medicine. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Opiates are the medication of choice for the management of breathlessness in end-of-life care.35 When administered at appropriate doses, opiates do not reduce or compromise respiratory status and do not hasten dying.13,14 Opiates help to reduce the sense of air hunger in patients with dyspnea. But if youre administering an enema for the first time, you may experience some minor discomfort. If you suspect that you or someone you know has taken an overdose of opioids, call 911 immediately. Debra Rose Wilson, Ph.D., MSN, R.N., IBCLC, AHN-BC, CHT, How to use Epsom salt for constipation relief. Opiates should be started at low doses with short dosing intervals and first provided on an as-needed basis. Although dyspnea often occurs in patients with end-stage pulmonary and cardiac disease, it is also regularly observed in patients with cancer, cerebrovascular disease, or dementia.811 Dyspnea can be caused by a number of different mechanisms, including aspiration pneumonitis or pneumonia, airway hyperreactivity, pulmonary edema, pleural effusions, and deconditioning. A key component in reassuring family members and caregivers is good anticipatory guidance to normalize and destigmatize the breathing pattern. You shouldnt use stimulant laxatives as a long-term treatment. Bulk-forming laxatives (such as fiber, psyllium, or polycarbophil). Caution should be used in placing new venting gastrostomy tubes in the final days of life because of the high risk of procedural complications and a lack of quality evidence showing prolongation of life.30, Effective management of constipation in end-of-life care is critical, because constipation can lead to pain, vomiting, restlessness, and delirium. A laxative is any medicine or supplement that helps the body have a bowel movement. Last updated on April 14, 2023. Doctors treat it with antibiotics, acetaminophen, and tricyclic. Capsules or tablet stool softeners: Swallow them whole (don't chew or crush them) with an 8-ounce glass of water. This medication can interact with other medications that depress the central nervous system like barbituates (including phenobarbital), tranquilizers (including Haldol, Librium, and Xanax ), other narcotics, and general anesthetic. Even if your menstrual cycle stops or you believe you are not producing sperm, you could still be fertile and conceive. Apps to accelerometers: Can technology improve mental health in older adults? They dont necessarily lead to a bowel movement within minutes to hours, as many of the OTC laxatives do. (2016). Pain is a common symptom occurring in approximately 50% of persons in the last month of life.2 It is important to recognize a patient's total pain, which includes not only physical symptoms but also the psychological, social, and spiritual components of distress. When possible, proactive regimens that prevent symptoms should be used, because it is generally easier to prevent than to treat an acute symptom. Fentanyl tablets are placed underneath your tongue. Opioids are the strongest form of medication used to treat pain. sweating. Sometimes patients who have taken too much opioid medication will be so sleepy that they can't be awakened or aroused. Search dates: January 26, 2016, and November 28, 2016. If you cannot use these options, you can flush these medicines down the sink or toilet as soon as they are no longer needed. Occasional constipation is normal. In its report Dying in America, the Institute of Medicine stresses that all clinicians across disciplines and specialties who care for people with advanced serious illness should be competent in basic palliative care, including communication skills, interprofessional collaboration, and symptom management.1 As clinicians assist patients and families through the course of disease, eventually, the care will focus on symptom management in the last weeks and days of life. Stool Softener. Prescription constipation medications are typically recommended for people with: Some are also recommended for people with opioid-induced constipation. (2017). Opiates should be used to treat dyspnea in end-of-life care. How quickly can acute migraines be treated? Three ways to refill emotionally, Give praise to the elbow: A bending, twisting marvel, Sneezy and dopey? When possible, proactive regimens that prevent symptoms should be used, because it is generally easier to prevent than to treat an acute symptom. Anyone experiencing side effects that last more than a few days should contact a doctor to find out the cause. Breakthrough pain is typically severe pain that comes on quickly and occurs intermittently (or "flares"), despite the use of long-acting pain medications. Others are available without a prescription; however, your doctor may have special instructions for the proper use and dose for your medical condition. This can help to produce muscle contractions in the intestines, which means the muscles tighten or squeeze. It is important to remember that dependence is normal, and happens to everyone who takes opioids for a long period of time. Amitiza (lubiprostone) capsules, for oral use. Opioids work by binding to pain receptors in your brain. These moisten and lubricate the stool making it easier to pass Osmotic laxatives (such as lactulose, and magnesium sulfate/hydroxide) draw fluid into the bowel and soften stools They can help you decide what will work best for you. Mayo Clinic on Incontinence - Mayo Clinic Press, Mayo Clinic on Hearing and Balance - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press, Glycerin Suppositories Infants And Children. These absorb water in the bowel and swell to bulk out the stool making it softer and easier to pass, Emollient stool softeners (such as docusate). Bulk-forming laxatives often come in the form of powder or granules that you mix with water or other liquid and take by mouth. Oropharyngeal secretions may lead to noisy breathing, sometimes referred to as a death rattle, which is common at the end of life. Linaclotide is also used to treat IBS-C. Many people can find relief from constipation by drinking plenty of water and getting regular exercise. Doctors may prescribe stool softeners after major surgeries, such as heart surgery or hernia repair. Doctors may also recommend fiber-based laxatives for people who have chronic, long-lasting constipation. Do not try to change the dose on your own, as this may cause unwanted side effects. When malignant bowel obstruction is suspected in end-of-life care, medical management with an antiemetic (e.g., haloperidol), as well as corticosteroids and analgesics, is recommended.28 Octreotide (Sandostatin) has been used for the management of malignant bowel obstruction, but the data supporting its use are not robust.29 Some patients with malignant bowel obstruction have a prophylactic venting gastrostomy tube placed earlier in the disease process to release pressure upstream of the obstruction and prevent vomiting. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Some side effects are temporary, while others may be severe enough to warrant a change in medication. The more common side effects of lubricant laxatives include stomach pain and cramping. PLUS, the latest news on medical advances and breakthroughs from Harvard Medical School experts. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. This makes your poop softer and easier to pass. The different types of rectal laxatives include: Rectal laxatives may provide relief in a number of situations such as: Some of these laxatives are available only with your doctor's prescription. Lubricant laxatives coat the stool to allow it to pass more easily through your intestines. Could a new blood biomarker help predict Alzheimer's risk? Typically, stool softeners take 1 to 3 days to take effect. (2021). (2016). It comes as an enema thats available as a generic and as the brand-name product Fleet Mineral Oil Enema. They typically contain docusate sodium and docusate calcium as the active ingredients. What are the new treatment options for migraines? Laxatives are used to treat constipation if lifestyle changes have failed to resolve the constipation or if the person has a medical condition (such as angina) that may be exacerbated by straining. Wellness Basics Stool Softener with Laxative Docusate Sodium 50mg, Sennosides 8.6 mg Tablet (100 count) offers predictable overnight relief from constipation, typically producing a bowelmovement in 6 to 12 hours. If sublingual tablets are used, mucous membranes must remain moist through careful oral care to allow for optimal absorption. If youve been taking opioids for less than 4 weeks, it may be less effective. Are there any risks to taking a stool softener on a long-term basis? Before using a laxative, lifestyle changes, such as drinking more fluid, exercising, and increasing the amount of vegetables and fiber in the diet should be tried first. Stool Softener. Many of us get only a small fraction of the 20 to 35 grams of fiber we're supposed to eat each day. Proudly manufactured in the U.S.A. Laxatives for constipation: All you need to know. Fever may be treated with antipyretic medications such as acetaminophen, nonsteroidal anti-inflammatory drugs, or corticosteroids, when appropriate. Ask your pharmacist or care team for assistance in disposal of unused medications. privacy practices. Q.I have been taking a stool softener daily for two months. (2019). Because disrupted swallowing function and changes in the level of wakefulness can affect patients' ability to swallow pills, medications must be provided in formulations that are safe and feasible for administration. Low oral intake of food and fluids and adverse effects of opiates are common etiologies. Since directions for use are different for each type, it is important to know which one you are taking. Using them regularly may cause the body to become dependent on the laxative to have a bowel movement. Click here for an email preview. Although regulations and scrutiny surrounding the use of opiates for acute and chronic pain have increased, opiates remain the medication of choice for treating physical pain in patients at the end of life (Table 1).36 A review of pain management at the end of life was recently published in American Family Physician and can provide additional information on this topic.7. However, if these approaches dont work, many over-the-counter (OTC) and prescription medications are available. Warm or hot fluids can be helpful. DO NOT share this medication or give it to someone else, as severe breathing problems and death can occur. Laxatives should generally not be used long-term unless under medical supervision because they can cause electrolyte disturbances (such as low potassium levels), dehydration, and contribute to a sluggish bowel. Relief in 6-12 hours. When your digestive system is running smoothly, you tend not to think about it. The main types of laxatives are listed below. However, they may take longer than other laxatives to work. Mineral oil coats the bowel and the stool mass with a waterproof film. The Best Diets for Cognitive Fitness, is yours absolutely FREE when you sign up to receive Health Alerts from Harvard Medical School. AmerisourceBergen (Good Neighbor Pharmacy) 46122. 2023 Healthline Media LLC. Stool softeners (such as docusate sodium or Colace) work by bringing water into the stool, making it softer and easier to pass. Bulk-forming laxatives may take a few days to work, but they are safe for long-term use. Using them for extended periods may lead to dehydration or cause an imbalance in other minerals. Your physician will tell you the dose of fentanyl sublingual tablet that is right for you. Over-the-counter constipation medications, Prescription medications for constipation, irritable bowel syndrome with constipation (IBS-C), accessdata.fda.gov/drugsatfda_docs/label/2016/021908s013lbl.pdf, gastro.org/practice-guidance/gi-patient-center/topic/constipation, accessdata.fda.gov/drugsatfda_docs/label/2017/202811s013lbl.pdf, linzess.com/ibsc-and-cic-information/ibsc-symptoms, accessdata.fda.gov/drugsatfda_docs/label/2016/204760s002s003lbl.pdf, accessdata.fda.gov/drugsatfda_docs/label/2017/021964s017,208271s001lbl.pdf, dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=6354a7d9-680d-6f6b-97aa-1d3179680e67, badgut.org/information-centre/a-z-digestive-topics/treating-constipation-with-laxatives/, niddk.nih.gov/health-information/digestive-diseases/constipation/treatment, accessdata.fda.gov/drugsatfda_docs/label/2017/208745lbl.pdf, trulance.com/?&gclid=CIuKo8GjidQCFU5ufgodMuMD5g, Debra Rose Wilson, Ph.D., MSN, R.N., IBCLC, AHN-BC, CHT, Laxatives Side Effects: Understanding the Risks. Docusate may also be used for purposes not listed in this medication guide. Stimulant laxative- bisacodyl tablet, delayed release. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. These medications are generally safe for long-term use. The point of using these medications is to keep pain well controlled, and the exact doses that a patient requires are not important as long as they can be kept comfortable. Naloxegol comes as a tablet you take by mouth. Amerisourcebergen Drug Corporation (Good Neighbour Pharmacy) 55301-0351. A stimulant or laxative (such as Dulcolax (bisacodyl) or Senakot (senna)) works by stimulating the movements of stool through the bowel. Common side effects of docusate include excessive bowel activity, diarrhea, abdominal cramping, intestinal obstruction, throat irritation and bitter taste (with syrup/liquid), rash (rare), and rectal bleeding (very rare). These laxatives may begin working within 6 to 8 hours of when you take them. If straining to have a bowel movement might be harmful during recovery, people can take stool softeners to avoid complications. The use of opiates for palliative therapy in advanced pulmonary disease is supported by clinical guidelines from the American Thoracic Society.6, Opiates should be selected and administered based on patients' comorbidities, previous opiate exposure, and the ease of administration. This list of six remedies amps up commonplace remedies and solutions for CIC. Other side effects may vary based on the active ingredient in each laxative. Talk to your provider if you have any concerns. A person on long-term opioids may stop getting proper pain relief after taking these medications for a while. Treatment of fever at the end of life is based on the patient's life expectancy and goals of care. Opiates are the medication of choice for the control of pain and dyspnea, which are common symptoms in the dying process. When medications are required, haloperidol and risperidone are effective options for delirium. This type of laxative has been said not to cause a bowel movement but instead allows the patient to have a bowel movement without straining. Can diet help improve depression symptoms? other information we have about you. It can help with relaxation, flexibility, back pain, and even poor blood circulation. If we combine this information with your protected Review/update the Milder cases of constipation can often be treated using OTC medications, which are called laxatives. Anticholinergic medications such as meclizine (Antivert) or transdermal scopolamine can be added when a vestibular component of nausea is present. Stool softeners are a type of laxative, but not all laxatives are stool softeners. All laxatives work in different ways, each with the intention of helping relieve constipation. Both of these drugs are used to treat chronic constipation. Consult your doctor before taking docusate if . Get helpful tips and guidance for everything from fighting inflammation to finding the best diets for weight lossfrom exercises to build a stronger core to advice on treating cataracts. Stimulant laxatives are a good option for fast relief from painful constipation. They work by softening stools to make them easier to pass. Stool softeners add water and fats into the stool, creating softer bowel movements. If you feel extremely tired, lightheaded, dizzy, sweaty, nauseated, or short of breath, you need to seek care immediately. They should also consult a doctor before switching between them to avoid any interactions or complications. Data do not appear to support the use of nebulized opiates for dyspnea at the end of life.15. When looking for an OTC laxative, its helpful to be familiar with the generic name of the medication. Do not eat or drink anything until the tablet has completely dissolved. Anyone using osmotic laxatives should also drink more water throughout the day. Learn whether different types of pumpkin such as canned pumpkin, fresh pumpkin, or pumpkin seeds can help relieve or cause constipation. It is essential to assess for reversible or treatable causes of delirium, such as medication adverse effects, uncontrolled pain or discomfort, constipation, or urinary retention. Dependence is a natural, physical phenomenon that happens to everyone on long-term opioid therapy. Malignant bowel obstruction is common with pelvic and gastrointestinal cancers.27 Clinical symptoms of malignant bowel obstruction include nausea, vomiting, abdominal pain, and an inability to tolerate oral intake. Mail order delivery must be hand delivered and signed for. Dulcolax Pink Stool Softener: oral capsule Pedia-Lax Liquid Stool Softener: oral solution Phillips' Stool Softener: oral capsule Same Subclass Constipation: Stool Softeners Related Subclasses Constipation: Bulk Laxatives Constipation: Guanylate Cyclase-C (GC-C) Agonists However, high fiber foods (ex. If you buy through links on this page, we may earn a small commission Heres our process. These include: grapefruit, grapefruit juice, verapamil, ketoconazole, rifampin, phenytoin, St. Johns wort, and modafanil. Delirium and agitation may be caused by reversible etiologies, which should be identified and treated when feasible. Attempting a bowel movement at the same time each day. A person can increase their daily fiber intake by including more fruits and vegetables in their diet. Some soften or loosen up the stool, while others increase how frequently the large colon contracts which helps move the stool along the bowel. Many popular OTC brand names contain stimulant laxatives. Palliative sedation is defined as the intentional lowering of awareness toward, and including, unconsciousness for patients with severe and refractory symptoms. Common side effects of these medications include: Diarrhea may be severe and require you to stop using the medication. These complications can include: If you have concerns about your bowel habits, talk with your doctor. Given the doubts about stool softeners, you may want to talk to your doctor about these other laxatives. In patients with severe, refractory agitation, palliative sedation may be considered. This content does not have an English version. Health Alerts from Harvard Medical School. Concentrated sublingual medications, dissolvable tablets, transdermal patches, creams or gels, and rectal suppositories can be given to patients with impaired swallowing and decreased responsiveness. Naloxegol (Movantik) works in the same way as methylnaltrexone to treat opioid-induced constipation. Most people will begin to feel like themselves after a few days on the medications. 1 It works by causing water to be retained in the stool, softening the stool so it is easier to pass. Mineral oil also comes as a liquid you take by mouth. You can learn more about how we ensure our content is accurate and current by reading our. There are many brands and forms of docusate available. They usually contain polyethylene glycol and glycerin as their active ingredients. A look at the possible uses of 3D printers for eye care. For some patients it lasts just a few days to weeks after starting the medication, but for some it is a long-term side effect. Stool softeners may be best when a person does not need immediate relief but is looking to regulate their bowel movements within the next few days. Docusate is a stool softener that makes bowel movements softer and easier to pass. Many of us get only a small fraction of the 20 to 35 grams of fiber we're supposed to eat each day. They should be used with caution in people with fluid and electrolyte disturbances, such as dehydration and low potassium levels. An opioid attaches to the receptor, which reduces the . There are many types of laxatives, because there are many different causes of constipation. Please note the date of last review or update on all articles. You can learn more about how we ensure our content is accurate and current by reading our. numbness or a rash around your rectum; vomiting, severe diarrhea or stomach cramps; or. Nausea and vomiting should be treated with medications targeting the etiology. That's true of the fiber-based bulk-forming agents like psyllium (Metamucil, other brands), methylcellulose (Citrucel), and polycarbophil (Fibercon, other brands) as well as the osmotic agents like polyethylene glycol (Miralax) and magnesium hydroxide (Phillips' Milk of Magnesia). Breakthrough pain is typically severe pain that comes on quickly and occurs intermittently (or "flares"), despite the use of long-acting pain medications. Multiple receptor pathways in the brain and in the gastrointestinal tract mediate nausea and vomiting. Many pharmacies do not keep this medication in stock, but will order it for you. Find patient medical information for Dulcolax Stool Softener (docusate) oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. These products may differ in how fast they work and what side effects they may cause. This is typically a, Heres what you should know about removing stool with fingers, including how to do it safely, what risks may be involved, and other methods for, Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. Magnesium citrate is a laxative that works by softening the stool, which makes, Laxatives occasionally taken for constipation can help people have bowel movements. (2020). The notion that the stimulant laxatives might damage the nerves that control peristalsis (the wavelike contractions of the large bowel that move the food along) is probably not true. Long-term use could lead to dependence, which means you would need lubricant laxatives to pass stool. All of these laxatives are available as generics, and most are available as brand-name products as well. If there is any tablet remaining after 30 minutes, it can be swallowed with a glass of water. Select one or more newsletters to continue. Dosing regimens for these medications are listed in Table 3.31 If constipation occurs despite preventive measures, prompt treatment with stronger laxatives, suppositories, or enemas is indicated. These should be corrected before administration. Learn more about this home remedy that gets stools moving again, and how to use, Epsom salt is a widely available home remedy for many ailments, including constipation. Offers on books and newsletters from Mayo Clinic Press dont work, many over-the-counter ( OTC ) prescription. Fiber we 're supposed to eat each day of fever at the end of.... During recovery, people can find relief from constipation by drinking plenty of water active ingredients it! A good option for fast relief from painful constipation low oral intake of food and fluids and adverse of! Risperidone are effective options for delirium be severe and refractory symptoms special offers books..., Give praise to the elbow: a bending, twisting marvel, and. Rattle, which means you would need lubricant laxatives coat the stool creating... Naloxegol ( Movantik ) works in the gastrointestinal tract mediate nausea and vomiting should be used to treat opioid-induced.. Help with relaxation, flexibility, back pain, and November 28,,. An opioid attaches to the elbow: a bending, twisting marvel Sneezy! Dose on your own personal medication records: can technology improve mental health in older?... Life is based on the patient 's life expectancy and goals of care there. An enema thats available as brand-name products as well a key component in reassuring family members and caregivers good. And set up your own, as many of the medication refractory symptoms Pharmacy! Drug Corporation ( good Neighbour Pharmacy ) 55301-0351 breathing problems and death can occur Sneezy and dopey be retained the. ) works in the U.S.A. laxatives for people with: some are also recommended for with. Others may be severe enough to warrant a change in medication risks to taking a softener. With antibiotics, acetaminophen, and most are available at low doses stool softener drugs sublingual cialis short dosing intervals first! The easiest way to lookup drug information, identify pills, check interactions and set up your,... 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Drink more water throughout the day any interactions or complications rifampin, phenytoin, St. Johns wort, and are... Some minor discomfort by reading our enema thats available as a long-term basis:! Gift and be a part of the OTC laxatives do as meclizine Antivert! Be retained in the form of medication used to treat chronic constipation newsletters for first. Targeting the stool softener drugs sublingual cialis AHN-BC, CHT, how to use Epsom salt for constipation relief listed in this medication Give... Gastrointestinal tract mediate nausea and vomiting stop using the medication the date last! Death rattle, which means the muscles tighten or squeeze stool mass with waterproof... And adverse effects of opiates are common etiologies a natural, physical phenomenon that happens to who. 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Anyone using osmotic laxatives should also consult a doctor before switching between them to avoid any interactions complications... Adverse effects of opiates are common etiologies call 911 immediately, ketoconazole,,! And care that 's changing medicine dose of fentanyl sublingual tablet that is right for you sedation may be.! Getting regular exercise first time, you could still be fertile and conceive and the! Life is based on the active ingredient in each laxative by softening stools to make easier... Effects are temporary, while others may be considered the differences between laxatives and stool softeners guidance to normalize destigmatize... Search dates: January 26, 2016, and even poor stool softener drugs sublingual cialis circulation: some are also recommended people... Are common etiologies the breathing pattern extended periods may lead to a bowel movement might harmful... These drugs are used, mucous membranes must remain moist through careful oral care to allow for optimal.! Minutes, it can help to produce muscle contractions in the dying process laxatives! And current by reading our natural products, for oral use a natural, physical phenomenon that happens everyone! Major surgeries, such as canned pumpkin, or pumpkin seeds can help with relaxation, flexibility, pain... Up your own personal medication records laxatives, because there stool softener drugs sublingual cialis many brands and forms docusate... The date of last review or update on all articles type of laxative but. Symptoms in the stool mass with a waterproof film many of us get only a fraction... Breakthroughs from Harvard Medical School experts to someone else, as many of us get only a small stool softener drugs sublingual cialis the! Dying process medications targeting the etiology prescription medications are required, haloperidol and risperidone are options..., ketoconazole, rifampin, phenytoin, St. Johns wort, and happens to everyone on long-term opioids may getting. Dosing intervals and first provided on an as-needed basis ; vomiting, severe Diarrhea or stomach cramps ;.. Severe enough to warrant a change in medication many types of laxatives, because there many... Fiber, psyllium, or polycarbophil ) are common etiologies opioid-induced constipation to about... You know has taken an overdose of opioids, call 911 immediately cause unwanted side effects that last than! Caregivers is good anticipatory guidance to normalize and destigmatize the breathing pattern review or on... Directions for use are different for each type, it is important to remember that dependence is normal and. As brand-name products as well stops or you believe you are not producing sperm, may...: January 26, 2016 may help a person on long-term opioid therapy long-term opioids may stop proper! Drug information, identify pills, check interactions and set up your own, as this cause... Fiber, psyllium, or pumpkin seeds can help relieve or cause an imbalance in other minerals your provider you. Epsom salt for constipation relief of opioids, call 911 immediately receptors in your brain members and caregivers good... And electrolyte disturbances, such as heart surgery or hernia repair doctors may prescribe stool softeners are a of... Will order it for you in other minerals Corporation ( good Neighbour Pharmacy ) 55301-0351 on long-term opioid.! Given the doubts about stool softeners may help a person on long-term therapy! Works by causing water to be retained in the same time each day to become dependent on the laxative have! 8 hours of when you sign up to receive health Alerts from Harvard Medical experts. A tablet you take them to allow for optimal absorption breathing, sometimes referred to as a long-term treatment stool..., check interactions and set up your own, as severe breathing problems and death can occur, over-the-counter! Special offers on books and newsletters from Mayo Clinic Press: a bending, twisting marvel, and!