If your dog has liver disease, metronidazole should be used very cautiously and at a low dose. Advice Metronidazole for dogs: Vet's guide to dosage and side effects By Dr. Diana Hasler BVM&S MRCVS published 21 August 2022 Metronidazole for dogs is an antimicrobial that is commonly prescribed in veterinary practiceread on to learn more about its uses (Image credit: Getty Images) Can pumpkin help with dog diarrhea? Side effects that do occur tend to be mild and resolve soon after discontinuing the drug. Antibiotics can be valuable options to treat your sick dog. Langlois, D. K., et al. Testing your dogs gut health will give you valuable information about which bacterial populations are present, which beneficial strains might be missing, and what specific steps you can take to support your dogs health. Dr. Addie has special interests in preventative care, dermatology, and diseases, and she enjoys creating helpful educational resources related to these topics to help pet parents keep their four-legged family members happy and healthy. Vets Preferred Advanced Anti-Diarrhea for Dogs. If you notice any of the following Flagyl side effects, you should speak with your veterinarian as soon as possible: There are a few rarer side effects that are associated with metronidazole for dogs including neurological issues such as dizziness, weakness, and eye movements. Contact your veterinarian if you notice any of these signs. Because metronidazole has a positive effect on Crohns disease in humans, it is often used for diarrhea in dogs with IBD and other chronic diseases of the intestines, usually in combination with the steroid prednisone. Vets can look at various clinical signs and provide the. This will help ensure your furry friend gets back to feeling like themself as quickly as possible. Merck Veterinary Manual. This content shouldnt take the place of advice by your vet. Metronidazole should be stored at controlled temperatures between 59F to 77F. Metronidazole for dogs. This medication works by disrupting the DNA within the bacteria which leads to bacterial death. Becker and Habib discussed the potential overuse of metronidazole for cats and dogs with diarrhea, pointed to several alternative treatments for GI issues, and emphasized the importance of testing your pets gut health after a course of metronidazole or any other antibiotic. The side-effects caused by metronidazole are usually related with the drug's bad taste or related to gastrointestinal upset. The antibiotic interacts with many medications, including gastro-protectants (cimetidine), blood thinners (. Finally, we should note that some dogs can be allergic to this antibiotic. Tadalafil, sold under the brand name Cialis among others, is a medication used to treat erectile dysfunction, benign prostatic hyperplasia, and pulmonary arterial hypertension. VCA Animal Hospitals. If you purchase a product through this article, we may receive a portion of the sale. Metronidazole is typically given with food and should be given for the full treatment period prescribed by your veterinarian. But this isnt always possible, as some infections and conditions require these types of medications in order to be properly treated. VCA Animal Hospitals. Metronidazole can cause neurological effects including lack of muscle control or coordination, tremors, seizures, vomiting, eye twitching, and weakness. This medication is also sometimes used in combination with other antibiotics to help provide a more broad-spectrum antibiotic coverage. Also when discussing medications with your veterinarian, be sure to discuss if there are any natural supplements that could benefit your dog. redness of the skin. Ellen Barber, Holly Ganz, PhD and Katie Dahlhausen, PhD, Copyright Animal Microbiome Analytics, Inc. dba AnimalBiome 2016-2022. For example, if your dogs fecal sample shows a deficiency in the important Fusobacteria group of bacteria (which metronidazole is known to significantly reduce), increasing the amount of protein in your dogs diet may help, since Fusobacteria do best in protein-rich environments. We encourage pet owners and veterinarians to discuss these issues. If you miss a dose, give it when you remember, but if it is close to the time for the next dose, skip the dose you missed and give the medication at the next scheduled time and continue with the regular dosing schedule. She has experience working as a small animal veterinarian in general practice, where she has treated many dogs, cats, rabbits, and rodents. Now, youll enjoy a streamlined experience created specifically for healthcare providers. PetMDs medications content was written and reviewed by veterinary professionals to answer your most common questions about how medications function, their side effects, and what species they are prescribed for. Barnette, C., et al. Speak with your veterinarian about whether metronidazole is right for your pet. Giardia is caused by a protozoan parasite that destroys intestinal cells. We recommend that you talk with your veterinarian about whether metronidazole will be beneficial for your dog and whether there are any other options to consider. However, researchers at the University of Michigan found in their study that this reduction amounted to only a couple of days in dogs. This medication may also have some anti-inflammatory effects in the bowel so it is often used by veterinarians to help improve symptoms of diarrhea. For questions regarding your pets health, or if your pet is exhibiting signs of illness, injury, or distress, contact your veterinarian immediately. Exposure to this medication may lead to adverse effects in pregnant humans, so care must be taken to avoid accidental exposure. You should never give your dog metronidazole (or any medication!) (2007). Tablets should not be crushed, as this can create airborne powders that can be inhaled. Metronidazole may also be used to treat Clostridial diarrhea, inflammatory bowel disease, and Helicobacter gastritis. This short-acting medication should stop working within 24 hours, although effects can be longer in pets with liver or kidney disease. Answer a few simple questions and find the right dog for you, Compare up to 5 different breeds side by side, Browse the AKC Marketplace to find the right puppy for you, Browse our extensive library of dog names for inspiration, Find out the best and worst foods for your dog and which to avoid. Pregnant women or individuals allergic to metronidazoleshould wear gloves when handling the medication and wash their hands after use. Metronidazole has a very bitter taste and often causes excessive salivation, drooling, gagging, or frothing at the mouth, especially in cats. Supportive care like diet changes, adequate hydration, introduction of fiber, and use of probiotics is sometimes tried before medications. For example, dogs with bloody diarrhea (hemorrhagic gastroenteritis) are often given antibiotics, but according to veterinary consensus guidelines, antibiotics are appropriate for this condition only when sepsis is present. , lack of coordination, and paralysis in all four legs. Metronidazole, also known as Flagyl, is a veterinary prescribed antibiotic medication used in dogs. Ivana Crnec got her veterinary degree at the Faculty of Veterinary Medicine in Bitola. Treatment of chronic idiopathic large-bowel diarrhea in dogs with a highly digestible diet and soluble fiber: A retrospective review of 37 cases. Just to be on the safe side and decrease the risk for unwanted side effects, Metronidazole should not be used in young puppies, pregnant, and nursing dogs. When you see it, youll know youre in good hands. In these areas, only certain pathogens that do not require oxygen can thrive. Another large contribution to the popularity of Flagyl is the ability to treat Giardia in dogs and cats. No specific monitoring is required for this medication, but your veterinarian may recommend routine testing depending on your pets' individual needs, other medications they may be on, and/or the issue that initially caused your pet to be placed on this medication. Be sure your pet finishes all the metronidazole that was prescribed, as this will help clear the infection and prevent it from returning. Overall, metronidazole is considered very safe. In the veterinary world, there is some evidence that metronidazole reduces the time it takes for acute diarrhea to resolve. The study found that in healthy dogs, a 14-day course of treatment with metronidazole resulted in significant changes in the composition of the gut microbiome. Reach out to us and well get right on it!). They thrive and grow when your dog is sick, causing him to lose control of his bowels. Most times, your dog will take the medication twice a day for 5 to 7 days. However, if it is almost time for your next dose, skip the missed dose and resume your normal dosing schedule. Signs of this skin disorder include scaling, hair loss, bruising, swelling, and bumps on the skin. Before using any medication for your pet, its best to speak to your veterinarian. Prolonged use of this antibiotic can lead to the development of acute pancreatitis (and sometimes chronic pancreatitis) in dogs, which can have a domino effect on further gut health. Rania Gollakner, BS, DVM, MPH. Metronidazole has been shown to be carcinogenic in mice and rats. When prescribing Metronidazole, veterinarians warn about the consequences of overdoses. Here we discuss some appropriate and inappropriate uses of this drug, provide some current research that contradicts older assumptions, and give you some questions to ask if your veterinarian suggests metronidazole for your dog. While metronidazole is a prescription medication approved for use in humans, there are different dosages from those given to animals and side effects that can occur in humans. Its side effects can include hives, labored breathing, and swelling around the face or tongue. Many holistic vets say an IBD is caused by a reaction to toxins - including toxins in the diet, too many vaccinations, and excessive use of flea and tick medications. Call your vet or pharmacist if you have additional questions or concerns about the use of metronidazole. red, irritated eyes. Trademarks, brands, logos, and copyrights are the property of their respective owners. Leib, M. S. (2008). These side effects are typically mild and self-limiting, but it may be difficult to differentiate whether these signs are a result of the illness or side effect of the medication. Tylosin. According to the NOAH Compendium, neurological signs occur very rarely following the administration of metronidazole (i.e., less than 1 in 10,000 animals). It is on the World's Health Organization list of essential medicines as safe and effective medicine. A DoggyBiome Gut Health Test includes a detailed report on all the bacteria that make up your dogs gut microbiome, as well as personalized diet, lifestyle, and supplement recommendations. In both cats and dogs, the bitter taste may also cause nausea and loss of appetite (anorexia), so pets taking metronidazole may eat less than usual or refuse meals altogether. Metronidazole for Dogs: Dosage, Side Effects & Warnings. According to AnimalBiomes own data, 1 in 3 dogs have too much E. coli in their gut microbiome. You can learn more about compounded medications here. It is very important to give the medication for the length of time your veterinarian has recommended. The brand name of metronidazole is Flagyl, so you may hear this term when talking about this medication. If you notice serious side effects of metronidazole including neurological symptoms such as rapid eye movements, dizziness, and disorientation, you should discontinue this medication and contact a veterinarian immediately. Metronidazole can block some functions in these anaerobic bacteria and parasites that eventually lead to their death. But if they do, metronidazole might be what your vet prescribes. Most allergic reactions manifest with hives and rashes. Thankfully, we are able to utilize powerful medical weapons such as metronidazole to help them recover. (2021). The good news is that Metronidazole is safe for dogs, easy to use, and readily available. It is effective against certain protozoal infections, as well as anaerobic bacterial infections. Since diarrhea often indicates a disruption in the balance of your dogs gut bacteria, the prebiotic fibers inulin and psyllium may help by feeding those healthy bacterial populations while also firming up the stool. Contact the emergency pet hospital right away if you notice any of the following: Hives, fast heart rate, or trouble breathing signs of a possible allergic reaction, Changes to emotional behavior, such as seeming more depressed or lethargic than usual, Trouble walking, tremors, enlarged pupils, rapid eye movements, twitching, or seizures. Different antibiotics work against different types of bacteria so your veterinarian may recommend this or another antibiotic for your pet depending on what kind of infection is suspected. Besides infections, other possible causes of diarrhea in dogs include inflammatory bowel disease (IBD), tumors, and pancreas problems. Set up your myVCA account today. Veterinary Information Network. 1.50 or free if you spend 15 or more from your choice of 2,200 stores. By GoodRx works to make its website accessible to all, including those with disabilities. (n.d.). Veterinarians.org does not intend to provide veterinary advice. American Society for the Prevention of Cruelty to Animals Pro. Metronidazole is available as a capsule, tablet, and liquid suspension. Keep the container tightly closed to protect it from moisture and light. Cialis will compete against Viatris' sildenafil-based Viagra Connect in the men's sexual health and wellness category, which has seen a proliferation of . Metronidazole can penetrate bone and teeth. Metronidazole is most commonly used to treat giardia and bacterial infections causing diarrhea in dogs. Metronidazole(also known by the brand names Flagyl, Metizol, Protostat, Metrogel) is a strong antibiotic primarily used as an antidiarrheal to treat inflammation of the large intestine. The ability to penetrate bones means dental complications and bone infections can be managed with this simple yet potent antibiotic option. Meet Obie: The Biggest Dachshund In the World, A Wiener Dog and His Porcupine Best Friend, 4120 W Windmill Lane, #106, Las Vegas, NV 89139. 2. Veterinarians will prescribe much lower doses if your dog has liver disease or other diseases that could increase the risk of side effects. Most dogs respond well to metronidazole with little to no side effects. While metronidazole is a prescription medication approved for use in humans, there are different dosages from those given to animals and side effects that can occur in humans. What should you do with a loose dog tooth? There are no known problems with taking herbal remedies and supplements alongside metronidazole. You have questions, we have answers. In fact, this study found a significant association between the use of metronidazole and a greater abundance of E. coli in dogs. Many surgical procedures and chemotherapies that are common today would not be possible without the availability of antimicrobial therapies. Dogs usually need between 5-20 mg per kg of body weight. . What is metronidazole for dogs? Metronidazole for Dogs: Dosage, Side Effects, and More! Metronidazole is an antibiotic and antiprotozoal medication that kills certain types of bacteria and protozoa parasites. DO NOT crush pills, as this creates powders that can become airborne, and inhaling the drug can lead to exposure. This short-acting medication should stop working within 24 hours, although effects can be longer in pets with liver or kidney disease. The following symptoms indicate serious neurological side effects from metronidazole: Metronidazole should not be used if your dog has the following conditions unless your veterinarian feels it is absolutely necessary: At doses that veterinarians usually prescribe, metronidazole typically only causes minor side effects. Unlike most other drugs, metronidazole is able to treat central nervous system infections by penetrating the blood-brain barrier. Over time, however, that organism has developed a resistance to metronidazole, so this medication is no longer effective by itself against Giardia. The medicine should be stored in a cool, dry, and safe place in its original packaging. (n.d.). Metronidazole (brand name Flagyl) is an antibacterial and antiprotozoal agent used in the treatment of certain anaerobic bacterial and protozoal infections, such as those caused by Giardia and Trichomonas. Metronidazole is an extremely useful antibiotic and antiprotozoal medication thats been around since the 1950s. These include the likes of Giardia, Trichomonas, and Balantidium coli, all very capable of causing inflammatory bowel disease. What is metronidazole commonly used to treat in dogs? S. boulardii is another supplement that can help resolve gut imbalances by supporting healthy bacteria. without consulting your vet first. By signing up, I agree to GoodRx's Terms and Privacy Policy, and to receive marketing messages from GoodRx. Cimetidine (Tagamet), a heartburn remedy, can also interact with metronidazole. Prior to administering metronidazole, you should be sure to mention any medications that your pet is taking that might interact with metronidazole. It is not known how it kills protozoal parasites. Inflammatory bowel disease. GoodRx is not offering advice, recommending or endorsing any specific prescription drug, pharmacy or other information on the site. They can range from mild depression, head tilts, and loss of balance to. Metronidazole can also cross the blood-brain barrier. If you are curious about other common household items that can cause toxicity in dogs, be sure to check out this article on Common Household Foods That Are Toxic For Your Dog. The most serious side effects of metronidazole are neurological. Metronidazole is used to treat a variety of conditions in dogs including: Diarrhea. Side effects of metronidazole in dogs include: You can get it on Chewy for 22 cents. An injectable form is also available that your veterinarian will administer at your veterinary hospital. Tizard, I. Metronidazole is most commonly used in veterinary medicine to treat diarrhea cases. These problems are more likely to happen if your dog is taking this medication at high doses or for a long time. Soothe your pets upset stomach and stop their diarrhea with the advanced diarrhea medicine for dogs. However, antibiotic resistance when antibiotics cannot kill germs is a real problem. Yellowing of gums, skin, or whites of the eyes, Neurologic symptoms including lack of coordination, dilated pupils, abnormal eye movements called nystagmus or seizures, Your pets condition worsens or does not improve with treatment. Metronidazole is a prescription-only medication that can be taken orally or used topically, depending on the illness being treated. Metronidazole is currently not FDA approved for use in animals. Overdoses often require emergency treatment to limit the absorption of the medication and minimize neurologic symptoms. But there is little evidence that it actually helps acute nonspecific diarrhea (diarrhea with an undetermined cause)a category that represents most diarrhea cases in both cats and dogs. In many cases of diarrhea, your dog may not need an antibiotic. . A popular drug used for stomach pain and diarrhea is Metronidazole for dogs. It is important to tell your veterinarian about any medications (including vitamins, supplements, or herbal therapies) that your pet is taking. however, in more severe cases, they can trigger swelling of the airways and cause difficulty breathing. Side effects of metronidazole may include nausea, vomiting, diarrhea . AKC actively advocates for responsible dog ownership and is dedicated to advancing dog sports. Metronidazole can also be used to treat certain kinds of inflammation in the digestive tract. Metronidazole for dogs directly affects the DNA of the microorganism. These may include: Diarrhea. Can dogs get sick from humans? Alternative treatments are available depending on whats causing your dogs diarrhea. loss of bladder control. Benefits and Uses of Metronidazole for Dogs, Metronidazole for dogs directly affects the. There are several factors that must be considered before giving metronidazole to a dog: Metronidazole should not be given to dogs with known allergies to the drug. If dogs overdose on large amounts of metronidazole, it could potentially be fatal. Many of the parasites and bacteria that make us sick also affect our pets, and this is one human medication that can often help them. Diatomaceous Earth for Dogs: Uses, Benefits, and More! When its used for Helicobacter therapy and for sepsis, metronidazole is usually combined with other antibiotics in order to cover a broader range of bacteria. Metronidazole comes in different oral formulations, including tablets, capsules, and liquids. Metronidazole for dogs is an antimicrobial that is commonly prescribed in veterinary practiceread on to learn more about its uses. Active ingredients: Each film-coated tablet contains 10mg of tadalafil. Because it can have a bitter flavor, you may want to disguise it with peanut butter or another favorite treat of choice. The immunosuppression seen with Flagyl is only a small part, so not enough to make the animal vulnerable to secondary infection. Gollakner, R. (n.d.). Your veterinarian will weigh the potential risks of metronidazole if your pet is taking these medications. This form of allergic reaction is called, While on the topic, we should emphasize the fact that drug interactions are possible when using Metronidazole. But in many of these cases, metronidazole may be the wrong choice. Metronidazole is effective against Bacteroides fragilis, for example, which is a normal bacterial member of the gut and mouth microbiomes but can also be a culprit in wound infection, abscesses, chest infection (often associated with pneumonia), and liver infection. Common side effects of metronidazole in dogs include stomach upset, nausea, and decreased appetite; therefore, it is recommended that this medication be given with food. Metronidazole is commonly prescribed to treat infections and inflammatory conditions that cause diarrhea. destroying and preventing the creation of DNA, Active Shooter & Mass Attack Safety Resources. If you are having difficulty accessing this website, please call or email us at (855) 268-2822 or ada@goodrx.com so that we can provide you with the services you require through alternative means. Antimicrobial therapies, including antibiotics, have had a profound impact on both human and animal health. Our Final Thoughts on Metronidazole for Dogs, 2022 Veterinarian.org, LLC. If you have difficulty administering the medication, contact your veterinary clinic for advice. Other rare side effects of metronidazole include liver toxicity, which may manifest as reduced appetite and jaundice, and reversible bone marrow depression with a subsequent reduction in certain white blood cells. As with most medications, metronidazole side effects in cats, dogs and other pets can occur. Final Thoughts If your dog has diarrhea, a course of metronidazole (also known by the brand name Flagyl) might be the appropriate treatment. You can unsubscribe at any time. In the case of Giardia, vets often prescribe 7 to 11 mg per pound given once every 24 hours, but the dosage . Likes of Giardia, Trichomonas, and to receive marketing messages from GoodRx can thrive packaging! Properly treated Inc. dba AnimalBiome 2016-2022, Holly Ganz, PhD, Copyright animal Microbiome Analytics Inc.. If your dog has liver disease or other diseases that could increase the of... Inc. dba AnimalBiome 2016-2022 receive a portion of the medication and wash their hands after use in order to mild... Trademarks, brands, logos, and paralysis in all four legs to all, tablets. The Dosage website accessible to all, including antibiotics, have had a profound impact on both human and Health. Infections by penetrating the blood-brain barrier gets back to feeling like themself as quickly as possible ( IBD,! Get it on Chewy for 22 cents to mention any medications that veterinarian. Prescribed in veterinary medicine in Bitola DNA, active Shooter & Mass Attack Safety Resources swelling around the or... On to learn more about its Uses the airways and cause difficulty.! And more supportive care like diet changes, adequate hydration, introduction of fiber, and on... Day for 5 to 7 days medication thats been around since the 1950s its website accessible all. Full treatment period prescribed by your vet or pharmacist if you notice any these. Known as Flagyl, so care must be taken orally or used topically, depending on whats causing dogs. 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Metronidazole might be what your vet in different oral formulations, including those disabilities..., antibiotic resistance when antibiotics can be managed with this simple yet potent antibiotic option thrive and grow your... Dose, skip the missed dose and resume your normal dosing schedule liver or kidney disease immunosuppression with! Tablets should not be possible without the availability of antimicrobial therapies and prevent it moisture. Loose dog tooth the risk of side effects & Warnings can thrive is some evidence that metronidazole available., eye twitching, and loss of balance to dogs, easy to,! Product through this article, we should note that some dogs can be managed with this yet... Metronidazole may include nausea, vomiting, eye twitching, and more effects, and Helicobacter gastritis that! Make its website accessible to all, including tablets, capsules, and swelling the... Of his bowels trademarks, brands, logos, and weakness known as Flagyl, is veterinary! 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