Although these medications are highly effective at preventing organ rejection and toning down the immune system response, that also means that the immune system cannot respond as well to certain infections. Drug-induced hematological cytopenia in kidney transplantation and the challenges it poses for kidney transplant physicians. CellCept can interact with several other medications. Drugs that you might be prescribed along with CellCept include: CellCept is also used in place of certain immunosuppressants. Myfortic was found to be as effective as CellCept at preventing organ rejection. CellCept may also be used off-label for other conditions, including: If youd like more information on the use of CellCept in treating these conditions, talk with your doctor. Stomach problems. Other side effects include: malignant neoplasm of skin, dizziness, and insomnia. Your healthcare professional will store the powder and intravenous solution. Its FDA-approved to help prevent organ rejection* after a heart, kidney, or liver transplant. If you take birth control pills, talk with your doctor before using CellCept. The forms of CellCept that are swallowed are all typically taken twice per day. People receiving immunosuppressants like CellCept have an increased risk of developing certain infections. Tell your doctor if you have symptoms of anemia during your CellCept treatment. Using more than the recommended dosage of CellCept can lead to serious side effects. Some medications are cleared from the body through kidney tubules (small tubes in the kidney that filter your blood). Specifically, CellCept is a type of immunosuppressant called an antirejection drug. Children 3 months of age and olderDose is based on body surface area (BSA) and must be determined by the doctor. Liver transplant survival rates have improved in the last 30 years. Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. The generic is considered to be as safe and effective as the original drug. Prograf injection should be discontinued as soon as you are able to take the oral form of Prograf. Its a place where people with certain conditions can find support and connect with others. If you have questions about using CellCept with other medications, talk with your doctor. Check with your doctor immediately if any of the following side effects occur: Some side effects may occur that usually do not need medical attention. If your doctor has prescribed CellCept and youre interested in using mycophenolate mofetil instead, talk with your doctor. A boxed warning is the most serious warning from the FDA. In addition to the use listed above, CellCept is also used off-label for other purposes at times. You may wonder how CellCept compares with other medications that are prescribed for similar uses. These include: To learn more about possible side effects your child may have while using CellCept, talk with their doctor. Yes, CellCept may be used off-label to treat lupus. This medicine may cause serious stomach or bowel problems (eg, ulcers, bleeding). When used during pregnancy, CellCept may cause congenital anomalies (also known as birth defects) or pregnancy loss. (Organ rejection occurs when the immune system attacks a transplanted organ.). This helps prevent others, including children and pets, from taking the drug by accident. You can learn more about how we ensure our content is accurate and current by reading our. * CellCept and Myfortic have boxed warnings for these side effects. Its prescribed to adults and children ages 3 months and older. The differences are one reason why doctors prescribe more than one drug to help prevent organ rejection in someone who has had a transplant. In these cases, your doctor may want to change the dose, or other precautions may be necessary. This card may help lower the cost of the drug for you. If you have unused medication that has gone past the expiration date, talk with your pharmacist about whether you might still be able to use it. Taking CellCept with cholestyramine (Prevalite) can make CellCept less effective by lowering the amount of CellCept in your body. If you miss a dose and it is less than 2 hours from your next scheduled dose, skip the missed dose and return to your regular schedule. If youre taking CellCept or Myfortic tablets, or other forms of CellCept that are swallowed, in most cases you should take them on an empty stomach. To learn more, see the Side effects explained section below. For more information on the possible side effects of CellCept, talk with your doctor or pharmacist. Tell your doctor right away if you become pregnant while using CellCept. Food and Drug Administration (FDA). If youre receiving the CellCept IV infusion, the typical dosage is 1,000 mg given twice per day. Do not stop taking this medicine without checking first with your doctor. If you have questions, talk with your doctor. They can tell you about other medications that may work well for you. The expiration date helps guarantee that the medication is effective during this time. Mycophenolate. Technically, CellCept is approved only for certain types of organ transplants. If you have questions about using CellCept to help prevent organ rejection, talk with your doctor. When the immune system is not working correctly, the body might start attacking itself. Organ rejection occurs when your immune system attacks a transplanted organ. CellCept (Mycophenolate Mofetil Capsules), CellCept (Mycophenolate Mofetil Injection Solution), CellCept (Mycophenolate Mofetil Oral Suspension), dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position, muscle cramps in the hands, arms, feet, legs, or face, muscle pain, stiffness, cramps, or weakness, numbness or tingling in the hands, feet, or lips, sores, ulcers, or white spots on the lips or in the mouth, pains in the stomach, side, or abdomen, possibly radiating to the back, sudden high fever or low-grade fever for months. They may have you go to the hospital for tests to determine whether youre experiencing organ rejection. Pharmaceutical Society of Australia "APPGuide online. If you notice any other effects, check with your healthcare professional. During your CellCept treatment, consider taking notes on any side effects youre having. This works in cancer treatment because cancer cells grow more quickly than normal healthy cells. If the side effects seem life threatening or you think youre having a medical emergency, immediately call 911 or your local emergency number. Applies to mycophenolate mofetil: oral capsule, oral powder for suspension, oral tablet. (2022). If you miss a dose, take it as soon as you remember. Weight gain wasnt a side effect reported in clinical studies of CellCept. Specifically, CellCept and Myfortic are a type of immunosuppressant called antirejection drugs. This is especially true for birth control pills that contain the active drug levonorgestrel. But if you have sudden weight gain or other symptoms of organ rejection, let your doctor know right away. (Phosphate is a chemical that naturally occurs in the body.). It works by preventing immune cells from multiplying. If a person goes into organ rejection, the new organ they have received might not work well, and it might even need to be removed. These lists contain up to 10 of the most common mild side effects that can occur with each drug, or with both CellCept and Prograf (when taken individually). Some side effects may not be reported. Should a spill occur, wipe it up using paper towels wetted with water to remove the powder or liquid. If you have concerns about hair loss during your CellCept treatment, talk with your doctor. You should not donate blood during your CellCept treatment or for at least 6 weeks after your last dose. To learn about the cost of the CellCept infusion and Prograf granules, talk with your doctor or pharmacist. Phenylketonuria (PKU)The oral suspension contains aspartame (phenylalanine), which can make this condition worse. CellCept can also make certain forms of birth control less effective. easy bleeding or bruising, swelling of the feet or ankles, mental/mood changes, weakness on one side of the body, or. Let your doctor know if you have a deficiency in an enzyme called hypoxanthine-guanine phosphoribosyl-transferase (HGPRT). This is the most serious warning from the Food and Drug Administration (FDA). These drugs make your body less likely to reject a transplanted organ. Learn about side effects, cost, and more. That is caused by immunosuppression and is one reason why people taking the drug have a greater risk of infection. Serious infections that have been reported by people using CellCept include: Symptoms of a serious infection may vary depending on the type of infection. Therefore, healthy cells are often damaged by chemotherapy. Phosphate binders are a group of drugs that are used to remove high levels of phosphate from your body. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Applies to mycophenolate mofetil: intravenous powder for injection, oral capsule, oral powder for reconstitution, oral tablet. Azathioprine to mycophenolate mofetil transition and risk of squamous cell carcinoma after lung transplantation. Some of the more common side effects of CellCept include: Infection is also a relatively common side effect. You can then share this information with your doctor. CellCept was compared with azathioprine (Azasan, Imuran) in clinical studies of adults who had a liver transplant. Usually Cellcept is given twice a day for a total dose of about 2000-3000 milligrams (mg) per day, but this dosage may be reduced. People with certain rare medical disorders should not take CellCept. Taking CellCept with phosphate binders can lower your blood levels of CellCept, making CellCept less effective. CellCept is also available as tablets and as a liquid that you swallow. CellCept is available is several forms taken by mouth: A 250-mg blue-brown capsule. Taking CellCept with drugs that are cleared from the body in this way can increase the levels of these drugs in your body. See additional information. To learn more, see the CellCept precautions section below. CellCept is also used off-label for other conditions at times. Phosphate binders are often used in people who have kidney problems and are receiving dialysis. CellCept has a boxed warning for this side effect. If youre breastfeeding or planning to do so, talk with your doctor before starting CellCept treatment. However, it does not work in exactly the same way as these other therapiesthey do not work on the same parts of the immune system. To learn about using Prograf in children, talk with your childs doctor. Examples of immunosuppressants used with CellCept include corticosteroids and cyclosporine (Neoral, Sandimmune). Due to this risk, your doctor will likely not prescribe CellCept if you have an HGRPT enzyme deficiency. This extra fluid in your body can make it seem like youve gained weight. Data sources include IBM Watson Micromedex (updated 5 June 2023), Cerner Multum (updated 5 June 2023), ASHP (updated 10 Apr 2023) and others. Keep from freezing. CellCept belongs to a group of drugs called antimetabolite immunosuppressants. (For more information, see the Taking CellCept with food section below.). Theyll likely also check your red blood cell counts regularly during your treatment. If you have questions, talk with your doctor. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). So, if you take CellCept with Prograf, you may experience hair loss from Prograf. Note: This document contains side effect information about mycophenolate mofetil. * CellCept has a boxed warning for this side effect. 19.79. excessive eye discharge. However, swelling in the ankles, feet, or legs can occur with this drug. Theyll then check them twice per month during the second and third months of treatment. Male patients with female partners should use an effective form of birth control during treatment and for at least 90 days after the last dose. Symptoms of infection may vary based on the type of infection you have. Today it is specifically approved to be used for kidney, heart, or liver transplants. They also included problems with the esophagus, kidneys, nervous system, and abnormalities of the arms and legs. This can lead to side effects from the chemotherapy drug. For instance, some interactions can interfere with how well a drug works. If you have questions, talk with your doctor about the best times to use your medicines. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. 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