Minor/Significance Unknown. STORAGE: Store at room temperature away from light and moisture. Keep all drugs out of the reach of children and pets. The recipient will receive more details and instructions to access this offer. If you have any questions, consult your doctor or pharmacist. Monitor patients for symptoms of active or occult gastrointestinal bleeding. Talk to your pharmacist for more details. For patients switching to rivastigmine patch from rivastigmine capsules or oral solution, it is recommended that those receiving below 3-mg twice-daily oral rivastigmine be switched to 4.6-mg/24-h patch with further titration as stated previously, while those receiving 3-6 mg twice daily can be switched directly to the 9.5-mg/24-h patch dose . Properly discard this product when it is expired or no longer needed. Additive bradycardia effect may result in syncope. Avoid or Use Alternate Drug. levobunolol increases toxicity of rivastigmine by pharmacodynamic synergism. Additive bradycardia effect may result in syncope. Limit alcoholic beverages. To reduce your risk of side effects (such as nausea and diarrhea), your doctor will start this medication using a lower dose of the patch and may increase your dose after 4 weeks. Serious - Use Alternative (1)timolol increases toxicity of rivastigmine by pharmacodynamic synergism. What side effects can this medication cause? Otherwise, call a poison control center right away. pharmacist if you have questions about the best way to throw out drugs. Use Caution/Monitor. Do not share your drugs with others and do not take anyone else's drugs. Either increases toxicity of the other by antidopaminergic effects, including extrapyramidal symptoms and neuroleptic malignant syndrome. Continue to use transdermal rivastigmine even if you feel well. Either increases toxicity of the other by antidopaminergic effects, including extrapyramidal symptoms and neuroleptic malignant syndrome. rivastigmine increases toxicity of ibuprofen by pharmacodynamic synergism. Monitor Closely (1)tolterodine and rivastigmine both decrease cholinergic effects/transmission. What special precautions should I follow? If someone applies extra or a higher dosage of rivastigmine patches but does not have any of the symptoms listed below, remove the patch or patches. It works by preventing the breakdown of a chemical that is important for the processes of memory, thinking, and reasoning. Use Caution/Monitor. Monitor patients for symptoms of active or occult gastrointestinal bleeding. Additive bradycardia effect may result in syncope. rivastigmine 9.5 mg/24 hour transdermal patch. PRECAUTIONS: Before using rivastigmine, tell your doctor or pharmacist if you are allergic to it (including any serious allergic skin reaction with past use of the patch); or if you have any other allergies. Oral solution may be swallowed directly from provided syringe or mixed with small glass of fluid. Increased GI symptoms. Additive bradycardia effect may result in syncope. Ask your doctor whether you will need to remove your patch before the test and apply a new patch afterward, and how to do so properly.Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).Older adults may be more sensitive to the side effects of this drug, especially QT prolongation (see above).During pregnancy, this medication should be used only when clearly needed. Minor/Significance Unknown. Use Caution/Monitor. Avoid or Use Alternate Drug. Apply a new patch to a different area to prevent skin irritation. QT prolongation can rarely cause serious (rarely fatal) fast/irregular heartbeat and other symptoms (such as severe dizziness, fainting) that need medical attention right away. This risk may increase if you use certain drugs (such as diuretics/"water pills") or if you have conditions such as severe sweating, diarrhea, or vomiting. hypersensitivity to drug or ingredient. Use Caution/Monitor. Sildenafil (Viagra), vardenafil (Levitra, Staxyn), tadalafil (Cialis) and avanafil (Stendra) are oral medications that reverse erectile dysfunction by enhancing the effects of nitric oxide, a natural chemical your body produces that relaxes muscles in the penis. Be sure the skin is free of powders, oil, and lotions. Modify Therapy/Monitor Closely. Dosage is based on your medical condition and response to treatment. rivastigmine increases and protriptyline decreases cholinergic effects/transmission. There may be drug take-back programs in your area. Rivastigmine is a medication used to manage and treat neurodegenerative disease, specifically dementia, in patients with Alzheimer and Parkinson disease. Monitor Closely (1)rivastigmine increases toxicity of ibuprofen IV by pharmacodynamic synergism. Talk to your doctor if you are using marijuana (cannabis).While wearing your patch, avoid exposing it to direct heat (such as prolonged direct sunlight, heating pads, electric blankets, heat lamps, saunas, hot tubs). rivastigmine increases toxicity of nabumetone by pharmacodynamic synergism. Use Caution/Monitor. Increased GI symptoms. Avoid or Use Alternate Drug. taken, how much, and when it happened. rivastigmine increases and pralidoxime decreases cholinergic effects/transmission. Transdermal rivastigmine may improve the ability to think and remember or slow the loss of these abilities, but it does not cure Alzheimer's disease or dementia in people with Parkinson's disease. Do not increase your dose or use this drug more often than prescribed. Monitor Closely (1)fesoterodine decreases effects of rivastigmine by cholinergic effects/transmission. The above information is provided for general DrugBank Accession Number. Avoid or Use Alternate Drug. Use Caution/Monitor. Avoid or Use Alternate Drug. Avoid or Use Alternate Drug. Use Caution/Monitor. Use Caution/Monitor. Do not cut the patch. Use Caution/Monitor. Monitor patients for symptoms of active or occult gastrointestinal bleeding. Some products that may interact with this drug include: aspirin/nonsteroidal anti-inflammatory drugs (NSAIDs, such as ibuprofen, naproxen), metoclopramide. Additive bradycardia effect may result in syncope. Do not touch your eyes while you are handling the patch. Your condition will not improve any faster, and your risk of side effects will increase.Use this medication regularly to get the most benefit from it. commonly, these are "preferred" (on formulary) brand drugs. Use Caution/Monitor. Use Caution/Monitor. NOTES: Do not share this medication with others.Your doctor should check your weight periodically to monitor for side effects. Increased GI symptoms. Use Caution/Monitor. Use Caution/Monitor. Either increases effects of the other by pharmacodynamic synergism. rivastigmine increases and amitriptyline decreases cholinergic effects/transmission. Shakiness, trouble moving around, or stiffness. You can bathe with the patch on.When changing your patch, remove the old patch, fold it in half with the sticky sides together, and throw it away out of reach of children and pets. Increased GI symptoms. Apply the patch to clean, dry skin that is relatively free of hair (upper or lower back or upper arm or chest). Monitor Closely (1)pyridostigmine and rivastigmine both increase cholinergic effects/transmission. Monitor Closely (1)rivastigmine increases and glycopyrrolate inhaled decreases cholinergic effects/transmission. Monitor patients for symptoms of active or occult gastrointestinal bleeding. Use Caution/Monitor. Monitor patients for symptoms of active or occult gastrointestinal bleeding. rivastigmine increases toxicity of ibuprofen IV by pharmacodynamic synergism. If you have questions about side effects, call your doctor. Use Caution/Monitor. Use Caution/Monitor. Call your doctor and do not apply any additional patches for the next 24 hours. Ask your doctor whether you will need to remove your patch before the test and apply a new patch afterward, and how to do so properly. Either increases effects of the other by pharmacodynamic synergism. If possible, withdraw anticholinesterase agents at least 24 hours before initiating corticosteroid therapy. Keep taking this medicine (rivastigmine capsules) as you have been told by your doctor or other health care provider, even if you feel well. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. Avoid or Use Alternate Drug. Serious - Use Alternative (1)levobunolol increases toxicity of rivastigmine by pharmacodynamic synergism. Effect of interaction is not clear, use caution. Additive bradycardia effect may result in syncope. This medicine can also be used for the treatment of mild to moderately severe dementia in adult patients with Parkinson's disease. For serious symptoms such as passing out or trouble breathing, call 911. Use Caution/Monitor. rivastigmine increases toxicity of salsalate by pharmacodynamic synergism. Does Rivastigmine Patch, Transdermal 24 Hours interact with other drugs you are taking? Do not apply more than one patch per day or leave the patch on for longer than prescribed. provider for the most current information. Manage and view all your plans together even plans in different states. Serious - Use Alternative (1)nadolol increases toxicity of rivastigmine by pharmacodynamic synergism. Monitor patients for symptoms of active or occult gastrointestinal bleeding. rivastigmine increases and oxybutynin transdermal decreases cholinergic effects/transmission. Use Caution/Monitor. Exelon, Nimvastid, Prometax. It is used to treat dementia in people with. Be sure to mention any of the following: antihistamines; bethanechol (Duvoid, Urecholine); ipratropium (Atrovent); and medications for Alzheimer's disease, glaucoma, irritable bowel disease, motion sickness, myasthenia gravis, Parkinson's disease, ulcers, or urinary problems. Monitor patients for symptoms of active or occult gastrointestinal bleeding. Use Caution/Monitor. Rivastigmine is in a class of medications called cholinesterase inhibitors. You may need to restart at a lower dose.Tell your doctor if your condition worsens. Check with your pharmacist. Monitor Closely (1)physostigmine and rivastigmine both increase cholinergic effects/transmission. Minor/Significance Unknown. Your doctor should check your weight periodically to monitor for side effects. Monitor Closely (1)trospium chloride decreases effects of rivastigmine by cholinergic effects/transmission. Other side effects include: anxiety, asthenia, depression, drowsiness, dyspepsia, fatigue, tremor, diaphoresis, flatulence, and malaise. rivastigmine and pilocarpine both increase cholinergic effects/transmission. However, you should still remove the patch at your regular patch removal time. Monitor patients for symptoms of active or occult gastrointestinal bleeding. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program. Make your tax-deductible gift and be a part of the cutting-edge research and care that's changing medicine. Access your plan list on any device mobile or desktop. You may need to restart at a lower dose. Additive bradycardia effect may result in syncope. To help you remember, change your patch at the same time each day. Check all prescription and nonprescription medicine labels carefully since many medications contain pain relievers/fever reducers (NSAIDs such as aspirin, ibuprofen, or naproxen) that if taken together with rivastigmine may increase your risk for stomach/intestinal bleeding. Information last revised July 2022. Use Caution/Monitor. This is not a complete list of possible side effects. Monitor Closely (1)rivastigmine increases and amitriptyline decreases cholinergic effects/transmission. Consult cardiologist if considering treatment. You are being redirected to Monitor Closely (1)rivastigmine increases toxicity of sulindac by pharmacodynamic synergism. Coadministration of ponesimod with drugs that decrease HR may have additive effects on decreasing HR and should generally not be initiated in these patients. Listed possible harms of rivastigmine include loss of appetite, feeling sleepy, urinary incontinence, hallucinations and falling, as well as increased signs of Parkinson's such as tremor or stiffness: a woeful list of side effects, particularly in the frail elderly. Monitor Closely (2)cevimeline and rivastigmine both increase cholinergic effects/transmission. Use Caution/Monitor. Compare formulary status to other drugs in the same class. solifenacin decreases effects of rivastigmine by cholinergic effects/transmission. rivastigmine increases toxicity of sulindac by pharmacodynamic synergism. Signs of an allergic reaction, like rash; Trouble controlling body movements that is new or worse. Store in a dry place. Monitor Closely (1)rivastigmine increases toxicity of naproxen by pharmacodynamic synergism. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Effect of interaction is not clear, use caution. Place the folded patch in the original pouch and dispose of it safely, out of the reach of children and pets. . Your list will be saved and can be edited at any time. Use Caution/Monitor. If any of these effects last or get worse, contact your doctor or pharmacist promptly.Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. This medication works by restoring the balance of natural substances (neurotransmitters) in the brain. Consult your doctor before breast-feeding. Otherwise, call a poison control center right away. Minor (1)rivastigmine increases toxicity of choline magnesium trisalicylate by pharmacodynamic synergism. Monitor Closely (1)rivastigmine increases and pralidoxime decreases cholinergic effects/transmission. This increases blood flow and allows you to get an erection in response to sexual . USES: Rivastigmine is used to treat confusion (dementia) related to Alzheimer's disease and to Parkinson's disease. This drug is available at a higher level co-pay. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. Contact the applicable plan Rinse off all of the soap and dry the area with a clean towel. Use Caution/Monitor. Increased GI symptoms. Low-dose aspirin, as prescribed by your doctor for specific medical reasons such as heart attack or stroke prevention (usually 81-162 milligrams a day), should be continued. Use Caution/Monitor. Use Caution/Monitor. Talk to your doctor about using rivastigmine safely. Concomitant use of anticholinesterase agents and corticosteroids may produce severe weakness in patients with myasthenia gravis. Wash the area with soap and warm water. Monitor Closely (1)rivastigmine increases toxicity of ibuprofen by pharmacodynamic synergism. Do not share this medication with others. Avoid or Use Alternate Drug. Most You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. caution: bradyarrhythmia. Avoid or Use Alternate Drug. Use Caution/Monitor. Rivastigmine is used to treat confusion (dementia) related to Alzheimer's disease and to Parkinson's disease. Monitor patients for symptoms of active or occult gastrointestinal bleeding. Monitor Closely (1)rivastigmine and succinylcholine both increase cholinergic effects/transmission. Monitor Closely (1)rivastigmine increases and hyoscyamine spray decreases cholinergic effects/transmission. Nausea, vomiting, loss of appetite/weight loss, diarrhea, weakness, dizziness, drowsiness, shakiness (tremors), and skin irritation at the application site may occur. DB00989. Use Caution/Monitor. Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Do not expose the patch to direct sunlight for very long. Additive bradycardia effect may result in syncope. Monitor patients for symptoms of active or occult gastrointestinal bleeding. While you are wearing a rivastigmine patch, protect the patch from direct heat such as heating pads, electric blankets, heat lamps, saunas, hot tubs, and heated water beds. Effect of interaction is not clear, use caution. Avoid or Use Alternate Drug. If the medication comes in contact with your eyes or if your eyes become red after handling the patch, rinse your eyes right away with water. tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. Do not apply more than one patch per day or leave the patch on for longer than prescribed. Minor (1)rivastigmine increases toxicity of ketorolac intranasal by pharmacodynamic synergism. If the patient is a child. atenolol increases toxicity of rivastigmine by pharmacodynamic synergism. Use Caution/Monitor. Use Caution/Monitor. rivastigmine and bethanechol both increase cholinergic effects/transmission. WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Copyright: Merative US L.P. 1973, 2023. Use Caution/Monitor. Minor/Significance Unknown. Older adults may be more sensitive to the side effects of this drug, especially QT prolongation (see above). if you are having surgery, including dental surgery, tell the doctor or dentist that you are using transdermal rivastigmine. Many people using this medication do not have serious side effects.Tell your doctor right away if any of these serious side effects occur: slow heartbeat, black stools, vomit that looks like coffee grounds, severe stomach/abdominal pain, seizures, trouble urinating.Get medical help right away if you have any very serious side effects, including: fast/irregular heartbeat, severe dizziness, fainting.A very serious allergic reaction to this drug is rare. Copyright, 2023. Use Caution/Monitor. Serious - Use Alternative (1)metoprolol increases toxicity of rivastigmine by pharmacodynamic synergism. Serious - Use Alternative (1)ponesimod, rivastigmine. Effect of interaction is not clear, use caution. Also, the medication may cause dizziness, sleeplessness, fatigue, and loss of appetite. Use Caution/Monitor. Monitor Closely (1)rivastigmine increases toxicity of diflunisal by pharmacodynamic synergism. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Use Caution/Monitor. amifampridine and rivastigmine both increase cholinergic effects/transmission. Use Caution/Monitor. Apply the patch as directed to a clean, dry, hairless area on the back, upper arm, or chest. Monitor Closely (1)rivastigmine increases and clomipramine decreases cholinergic effects/transmission. Concomitant use of anticholinesterase agents and corticosteroids may produce severe weakness in patients with myasthenia gravis. Use Caution/Monitor. rivastigmine increases toxicity of fenoprofen by pharmacodynamic synergism. Do not start, stop, or change the dosage of any medicines without your doctor's approval. Use Caution/Monitor. Avoid or Use Alternate Drug. Rivastigmine does not cure either of these diseases, but it may improve memory . Monitor Closely (1)darifenacin decreases effects of rivastigmine by cholinergic effects/transmission. Rivastigmine is used to treat mild to moderate dementia caused by Alzheimer's or Parkinson's disease. Joubin Khorsand, M.D., F.A.C.S . However, as Alzheimer's disease gets worse, there will be less and less ACh, so rivastigmine may not work as well. Remove the old patch first before applying a new patch. Effect of interaction is not clear, use caution. Heat may cause more drug to be released into your body, increasing the chance of side effects.If you are going to have an MRI test, tell testing personnel that you are using this patch. Use Caution/Monitor. Additive bradycardia effect may result in syncope. If you have had a skin reaction to this medicine (rivastigmine capsules) or another form of this medicine (rivastigmine capsules) in the past. Potential for prolonged neuromuscular blockade. Do not wear 2 patches at the same time. Effect of interaction is not clear, use caution. Background. what signs you had. What do I need to tell my doctor BEFORE I take Rivastigmine Capsules? Rivastigmine is a medication used to manage and treat neurodegenerative disease, specifically dementia, in patients with Alzheimer and Parkinson disease. Use Caution/Monitor. Wash your hands with soap and water after each application. Avoid or Use Alternate Drug. Effect of interaction is not clear, use caution. AHFS Patient Medication Information. galantamine and rivastigmine both increase cholinergic effects/transmission. The rivastigmine patch was well tolerated by the patients switching from rivastigmine capsules in the IDEAL study open-label extension ().The AEs reported most frequently during weeks 1-4 of the open-label extension (the period of time that all patients were on the 9.5 mg/24 h patch) are presented in Table 2.During the first 4 weeks of the open-label extension, patients formerly randomized . Use Caution/Monitor. This medicine is available only with your doctor's prescription. Drug information provided by: Merative, Micromedex. This medicine is used for the treatment of adult patients with mild to moderately severe Alzheimer's dementia, a progressive brain disorder that gradually affects memory, intellectual ability and behaviour. Minor (1)rivastigmine increases and desipramine decreases cholinergic effects/transmission. Tell your doctor about the allergy and Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. You can bathe with the patch on. Monitor patients for symptoms of active or occult gastrointestinal bleeding. Use Caution/Monitor. Use Caution/Monitor. Rivastigmine will not cure or stop Alzheimer's disease or Parkinson's disease from getting worse, however, rivastigmine can improve the thinking ability in some patients. Management of neuropsychiatric symptoms of dementia. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. One of the earliest and biggest changes is that there is less of a chemical called acetylcholine (ACh). Use Caution/Monitor. Heat may cause more drug to be released into your body, increasing the chance of side effects. rivastigmine increases and clomipramine decreases cholinergic effects/transmission. Medically reviewed by Drugs.com. Written by Cerner Multum. Talk to your doctor if you are using marijuana (cannabis). Rivastigmine may increase serum concentration of succinylcholine. Use Caution/Monitor. The American Society of Health-System Pharmacists, 4500 East-West Highway, Suite 900, Bethesda, Maryland. Use Caution/Monitor. Use Caution/Monitor. Hepatobiliary Disorders: Abnormal liver function tests, hepatitis, Psychiatric Disorders: Aggression, nightmares, Skin and Subcutaneous Tissue Disorders: Allergic dermatitis, application site hypersensitivity (patch), blister, disseminated allergic dermatitis, Stevens-Johnson syndrome, urticarial, Hypersensitivity to rivastigmine or carbamates, History of application site reaction with transdermal patch, May induce/exacerbate extrapyramidal symptoms, Gastrointestinal adverse reactions may include significant nausea, vomiting, diarrhea, anorexia/decreased appetite, and weight loss, and may necessitate treatment interruption; dehydration may result from prolonged vomiting or diarrhea and can be associated with serious outcomes, Medication errors with transdermal patches have resulted in serious adverse events; some cases have required hospitalization, and in rare instances, medication errors have led to death; most of the errors have involved not removing the old patch when putting on a new one and the use of multiple patches at the same time, Skin application site reactions may occur with transdermal application and are usually mild or moderate in intensity; these reactions are not in themselves an indication of sensitization; however, use of rivastigmine patch may lead to allergic contact dermatitis, Isolated postmarketing reports of disseminated hypersensitivity reactions of the skin irrespective of the administration route (oral or transdermal); treatment should be discontinued if disseminated hypersensitivity reaction of the skin occurs, There are no adequate data on developmental risks associated with use of drug in pregnant women, There are no data on presence of drug in human milk, effects on breastfed infant, or on milk production; the drug and its metabolites are excreted in rat milk following oral administration of rivastigmine; levels of rivastigmine plus metabolites in rat milk are approximately 2 times that in maternal plasma; developmental and health benefits of breastfeeding should be considered along with mothers clinical need for therapy and any potential adverse effects on breastfed infant from drug or underlying maternal condition. Monitor Closely (1)rivastigmine increases toxicity of fenoprofen by pharmacodynamic synergism. It is also important information to carry with you in case of emergencies. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.In Canada - Call your doctor for medical advice about side effects. US residents can call their local poison control center at 1-800-222-1222. Uses Warnings Before taking Side effects Dosage Interactions What is rivastigmine? Effect of interaction is not clear, use caution. rivastigmine increases toxicity of ketoprofen by pharmacodynamic synergism. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. Avoid or Use Alternate Drug. Use Caution/Monitor. Use Caution/Monitor. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. 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