Only one-sixth of the quetiapine dose is needed when taken with drugs that are CYP3A4 inhibitors (for example, ketoconazole, ritonavir, or nefazodone). When the weather is hot, drink a lot of fluids and dress lightly. Tell the doctor right away if your baby develops symptoms such as muscle stiffness or shakiness, unusual sleepiness, or difficulty feeding. Sign up for free and stay up to date on research advancements, health tips, current health topics, and expertise on managing health. For males, it may result in decreased sexual ability, inability to produce sperm, or enlarged breasts. Many drugs besides quetiapine may affect the heart rhythm (QT prolongation), including amiodarone, moxifloxacin, procainamide, quinidine, sotalol, thioridazine, among others. Your doctor may also need to monitor your lipid levels on quetiapine initiation and periodically thereafter as quetiapine may increase LDL-cholesterol and triglyceride levels. Can be given once daily, or divided into three doses per day depending on response and tolerability. However, studies have shown that a small number of people (especially people younger than 25) who take drugs to treat depression may experience worsening depression, other mental/mood symptoms, or suicidal thoughts/attempts. Talk to your doctor if you experience any changes in your mood or you develop anxiety, panic attacks, insomnia, get easily agitated, or have thoughts of suicide. It will not be wrong to say that because of the relationship between the start of new drug and headache, we are establishing the relationship, but this does not hold true. Do not double the dose to catch up. If you overheat, quickly look for a place to cool down and rest. Tell your doctor if you are pregnant, intending to become pregnant, or breastfeeding because quetiapine may not be suitable for you. Drugs used to treat depression can help prevent suicidal thoughts/attempts and provide other important benefits. Constipation. May increase blood pressure in adolescents. This drug may also cause significant weight gain and a rise in your blood cholesterol (or triglyceride) levels. Feeling dizzy. After 40 weeks, approximately 24% of patients taking quetiapine experienced a recurrence of a mood event compared with over 50% of those taking a placebo tablet (a pretend pill). It has several potential side effects to be aware of. If you have any questions, ask your doctor or pharmacist. Hyperglycemia: Adults: In controlled clinical trials of 12 weeks or less, 2.4% of patients with normal (less than 100 mg/dL) fasting plasma glucose (FPG) had at least 1 FPG reading of 126 mg/dL or greater (vs. placebo 1.4%) during treatment. Get medical help right away if you have any of the following symptoms: fever, muscle stiffness/pain/tenderness/weakness, severe tiredness, severe confusion, sweating, fast/irregular heartbeat, dark urine, signs of kidney problems (such as change in the amount of urine). You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. Many people using this medication do not have serious side effects. Get medical help right away if you have any of the following symptoms: fever, muscle stiffness/pain/tenderness/weakness, severe tiredness, severe confusion, sweating, fast/irregular heartbeat, dark urine, signs of kidney problems (such as change in the amount of urine). 10 Ways to Improve Your Entire Family's Nutrition View Blog Post. This medication may interfere with certain laboratory tests (including urine tests), possibly causing false test results. Since untreated mental/mood problems (such as schizophrenia, bipolar disorder, depression) can be a serious condition, do not stop taking this medication unless directed by your doctor. Your doctor may need to adjust your diabetes medication, exercise program, or diet. Quetiapine also helps to calm acute manic episodes in people with bipolar I disorder. It may also improve your mood, sleep, appetite, and energy level. There is a problem with Tell the doctor right away if you notice worsening depression/other psychiatric conditions, unusual behavior changes (including possible suicidal thoughts/attempts), or other mental/mood changes (including new/worsening anxiety, panic attacks, trouble sleeping, irritability, hostile/angry feelings, impulsive actions, severe restlessness, very rapid speech). Children may be at higher risk for certain side effects while taking this medication, such as increased blood pressure or increased prolactin (see also Side Effects section). Discuss the risks and benefits of treatment with your doctor. Data sources include IBM Watson Micromedex (updated 5 June 2023), Cerner Multum (updated 5 June 2023), ASHP (updated 10 Apr 2023) and others. Since untreated mental/mood problems (such as schizophrenia, bipolar disorder, depression) can be a serious condition, do not stop taking this medication unless directed by your doctor. Before taking quetiapine, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. Tell your doctor if your condition lasts or gets worse. Most people are started on a lower dosage which is gradually increased to reduce the risk of side effects such as drowsiness and low blood pressure. Get up slowly when going from a lying or sitting position to standing. Ask your pharmacist about using those products safely. This medication is used to treat certain mental/mood conditions (such as schizophrenia, bipolar disorder, sudden episodes of mania or depression associated with bipolar disorder). Lab and/or medical tests (such as blood sugar, blood pressure, cholesterol levels, eye exams, weight, blood counts) should be done before you start taking this medication and while you are taking it. A child with a history of hypertension experienced a hypertensive crisis. Alcohol may enhance these effects. http://womensmentalhealth.org/clinical-and-research-programs/pregnancyregistry/, https://www.drugs.com/pro/quetiapine-fumarate-tablets.html. Quetiapine is. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. Quetiapine extended-release tablet is also used together with other antidepressants to treat major depressive disorder. Available for Android and iOS devices. These results were not adjusted for normal growth. Be careful when going from a sitting or lying down position to a standing position as quetiapine may make you feel dizzy or light-headed, which may increase your risk of falling. In Canada - Call your doctor for medical advice about side effects. People with liver disease or taking other medications that may interact with quetiapine may need a dosage adjustment. Along with its needed effects, quetiapine may cause some unwanted effects. For patients with baseline borderline to high FPG (100 mg/dL or higher), 11.7% had at least 1 FPG reading of 126 mg/dL or greater (vs. placebo, 11.8%). This product may contain inactive ingredients, which can cause allergic reactions or other problems. Things to remember when you fill your prescription. Do not start, stop, or change the dosage of any medicines without your doctor's approval. Your doctor may need to adjust your diabetes medication, exercise program, or diet. Quetiapine is an antipsychotic that calms and sedates, helping to relieve psychotic thoughts and manic and depressive behavior. Make your tax-deductible gift and be a part of the cutting-edge research and care that's changing medicine. In some cases, this condition may be permanent. This medication may rarely cause a very serious condition called neuroleptic malignant syndrome (NMS). Tell your doctor right away if you have symptoms of high blood sugar such as increased thirst/urination. Quetiapine fumarate is not approved for the treatment of patients with dementia-related psychosis.Suicidal Thoughts and BehaviorsIncreased risk of suicidal thoughts and behavior in children, adolescents and young adults taking antidepressants.Monitor for worsening and emergence of suicidal thoughts and behaviors. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Properly discard this product when it is expired or no longer needed. We comply with the HONcode standard for trustworthy health information. In addition, animal studies have reported delays in skeletal ossification at approximately 1 and 2 times the maximum recommended human dose (MRHD) in both rats and rabbits, and an increased incidence of carpal/tarsal flexure (minor soft tissue anomaly) in rabbit fetuses. A very serious allergic reaction to this drug is rare. Quetiapine belongs to a group of medicines called antipsychotics. Dizziness and lightheadedness can increase the risk of falling. The average length of duration for the trials was 10 weeks with the cause of death in the majority of cases, though not all, reported as either cardiovascular (e.g., heart failure, sudden death) or infectious (e.g., pneumonia) in nature. All rights reserved. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. Quetiapine may cause a condition that affects the heart rhythm (QT prolongation). Ask about video and phone sessions. Get medical help right away if you have any very serious side effects, including: fainting, seizure, severe dizziness. May not be suitable for people with diabetes, or may precipitate diabetes, especially in those with pre-existing risk factors (such as obesity and lack of physical activity). Rarely, males may have a painful or prolonged erection lasting 4 or more hours. There is also a fast-dissolving form of Levitra, called Staxyn, that you put under your tongue. Quetiapine may be used as the sole therapy for the treatment of depressive episodes in people with bipolar I or bipolar II disorder. Alcohol or marijuana (cannabis) can make you more dizzy or drowsy. Mayo Clinic on Incontinence - Mayo Clinic Press, Mayo Clinic on Hearing and Balance - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press, dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position, changes in patterns and rhythms of speech, increased blinking or spasms of the eyelid, rapid or worm-like movements of the tongue, shakiness in the legs, arms, hands, or feet, sores, ulcers, or white spots on the lips or in the mouth, swelling of the face, arms, hands, feet, or lower legs, trembling and shaking of the hands and fingers, trouble with breathing, speaking, or swallowing, uncontrolled movements of the arms and legs, uncontrolled twisting movements of the neck, trunk, arms, or legs, Aching or discomfort in the lower legs or sensation of crawling in the legs, blistering, peeling, or loosening of the skin, muscle cramps, spasms, stiffness, or twitching, painful or prolonged erection of the penis, pains in the stomach, side, or abdomen, possibly radiating to the back, puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue, red skin lesions, often with a purple center, unusual bleeding or bruising unusual drowsiness, dullness, or feeling of sluggishness. Lehi, Utah 84043. If you notice other effects not listed above, contact your doctor or pharmacist. Revised 06/2022. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Register patients who do become pregnant while taking quetiapine on the National Pregnancy Registry for Atypical Antipsychotics at 1-866-961-2388 or online at. Quetiapine is a medication that works in the brain to treat schizophrenia. Mayo Clinic does not endorse companies or products. Read the Medication Guide and, if available, the Patient Information Leaflet provided by your pharmacist before you start using quetiapine and each time you get a refill. Drug interactions may change how your medications work or increase your risk for serious side effects. If you are planning pregnancy, become pregnant, or think you may be pregnant, immediately discuss with your doctor the benefits and risks of using this medication during pregnancy. It works by helping to restore the balance of certain natural substances (neurotransmitters) in the brain.This medication can decrease hallucinations and improve your concentration. Quetiapine Fumarate Tablets. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. Keep taking this medication even if you feel well. These all improve blood supply to the penis. The dosage is based on your medical condition, response to treatment, and other medications you may be taking. Consult your pharmacist or local waste disposal company. Usually, Levitra should be taken at least 1 hour before sexual activity. No patients with a baseline fasting glucose level lower than 126 mg/dL had a treatment-emergent blood glucose level greater than 126 mg/dL. privacy practices. May not be suitable for some people including those with cataracts, heart disease, high cholesterol, thyroid dysfunction, abnormal blood counts, high prolactin levels, or liver disease. Also, you may experience symptoms such as trouble sleeping, nausea, headache, diarrhea, irritability. What is quetiapine? Seek urgent medical advice if these symptoms develop. During pregnancy, this medication should be used only when clearly needed. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Quetiapine (Seroquel) is an atypical antipsychotic that's used to improve mood, thoughts, and behaviors for people with schizophrenia and bipolar disorder. You more dizzy or drowsy therapy for the treatment of depressive episodes in people with bipolar I or II. 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