They may suggest a treatment to manage your symptoms. Information is also available online at https://www.poisonhelp.org/help. Do not take a double dose to make up for a missed one. Yes, older people (ages 65 years and older) may have an increased risk of side effects from metoprolol. Both oral forms of metoprolol are used in adults to: Metoprolol tartrate is used in adults to improve survival after a heart attack. Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. Do not double the dose to catch up. If you do have bothersome side effects that dont improve, theyll likely go away if your doctor reduces your dose, or after you stop treatment. Last medically reviewed on October 23, 2022. Metoprolol is also used sometimes to treat certain types of irregular heartbeats. URL of this page: https://medlineplus.gov/druginfo/meds/a682864.html. The CNS side effects are associated with the lipophilic properties of beta-blockers, which allow them to rapidly penetrate the blood-brain barrier [1,2]. Multiple studies have reported central nervous system (CNS) side effects associated with useof beta-blockers. Do not store the mixture for more than 60 minutes. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Joint pain can sometimes be eased with gentle movement. Metoprolol is a prescription medicine used to treat high blood pressure. The incidence of neuropsychiatric side effects in beta-blockers is associated with their lipophilicity, which is the ability of the drug to cross the blood-brain barrier [5]. Check your blood sugar levels regularly as directed by your doctor. The cardiologist discontinued his amiodarone due to his ataxia, but continued his metoprolol. Metoprolol succinate extended-release (ER) tablets come in strengths of 25 milligrams (mg), 50 mg, 100 mg, and 200 mg. As with many drugs, your risk of side effects with metoprolol ER may be higher if you take a higher dose. This research was supported in part by HCA Healthcare and/or an HCA Healthcare affiliated entity. This branded product is no longer on the market. The level of metoprolol in your body increases soon after you take the tablet, then decreases until your next dose is due. Your risk of side effects with metoprolol tartrate immediate-release tablets may also be higher if you take a higher dose. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program. What is the best time of day to take blood pressure medication? He gave a past medical history of aortic valve replacement, hypertension, hyperlipidemia, benign prostate hyperplasia, Barretts esophagus, mild dementia, and chronic back pain. There is controversy regarding the selection of beta-blockers in the . you should know that metoprolol may make you drowsy. But metoprolol can sometimes cause or worsen heart failure. The use of beta-blockers in these patients is controversial due to its potential side effect of causing anxiety and depression despite well-established benefits [2]. A retrospective study by Gliebus and Lippa found that beta-blockers caused memory impairment in people with pre-existing cognitive impairment. High blood pressure is a common condition and when not treated, can cause damage to the brain, heart, blood vessels, kidneys and other parts of the body. Metoprolol tartrate / hydrochlorothiazide. The patients symptoms improved afterdecreasinghis metoprolol dose. Sexual side effects of high blood pressure medications. official website and that any information you provide is encrypted Medically reviewed by Drugs.com. Examples include lumefantrine, propafenone, quinidine, SSRI antidepressants (such as fluoxetine, paroxetine), St. John's wort, among others. Some conditions may become worse when you suddenly stop this drug. Rietveld L, van der Hoek T, van Beek MHCT, Schellekens AFA. Its common to have dizziness while taking metoprolol. Although not all of these side effects may occur, if they do occur they may need medical attention. Cove-Smith and Kirk reported a significant increase in sleep disturbances and restless nights in patients on metoprolol compared to atenolol [3]. This medication may be prescribed for other uses; ask your doctor or pharmacist for more information. Stroke and heart attack are medical emergencies. If they determine the problems are caused by metoprolol, they may recommend switching you to a different treatment for your condition. Published on September 13, 2022 Key takeaways: Metoprolol (Lopressor, Toprol XL) is a beta blocker used to treat conditions like high blood pressure, chest pain, and heart failure. tell your doctor if you have a slow or irregular heartbeat, heart failure, or problems with blood circulation. The patients symptoms were believed to be secondary to orthostatic hypotension; orthostatic vitals were supine blood pressure (BP) of 150/80 mmHg and standing BP of 130/70 mmHg. Metoprolol injection is given as an infusion into a vein. metoprolol toxicity, metoprolol side effects, cns side effects, metoprolol therapy, bizzare and vivid dreams, sleep disturbances, delirium, beta-blocker side effects. It is believed the role of norepinephrine in memory is related to its role in signaling through hippocampal beta 1-adrenergic receptors. They can investigate the possible cause. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. lower high blood pressure reduce chest pain (angina) However, metoprolol tartrate is also used to treat and prevent heart attacks, while metoprolol succinate is also used to treat heart. So you may be more likely to have certain side effects with the immediate-release form of the drug. chronic obstructive pulmonary disease (COPD), nctr-crs.fda.gov/fdalabel/services/spl/set-ids/99ecc717-38ab-4d00-8bf2-86a41b1c7977/spl-doc, nctr-crs.fda.gov/fdalabel/services/spl/set-ids/9d9a8af1-ff31-4bd5-8e8e-584c3663a41a/spl-doc, 7 Home Remedies for Managing High Blood Pressure, Oral Estrogen May Raise Your Risk of Hypertension by 19% Compared to Other Forms of Hormone Replacement Therapy, Debra Sullivan, Ph.D., MSN, R.N., CNE, COI, Hypertension Is Known as the Silent Killer, and Heres What You Need to Know, What Parents Need to Know About Persistent Pulmonary Hypertension of the Newborn. CNS-related side-effects with metoprolol and atenolol. The influence of beta- blockers on delayed memory function in people with cognitive impairment. Ask a doctor before using this medicine if you are breast-feeding. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position. If the side effects seem life threatening or you think youre having a medical emergency, immediately call 911 or your local emergency number. Tell your doctor if you are pregnant or plan to become pregnant. Recognizing the symptoms can help you quickly receive the correct treatment. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. In a couple of weeks, rock overlords Queens Of The Stone Age will return with their new album In Times New Roman; we've already posted the singles "Emotion Sickness" and "Carnavoyeur." Learn AboutMetoprolol (Metoprolol Tartrate). Its not likely. Drug class: cardioselective beta blockers, fast, pounding, or racing heartbeat or pulse, inability to move the arms, legs, or facial muscles, pain, tension, and weakness upon walking that subsides during periods of rest, paleness or cold feeling in the fingertips and toes, seeing, hearing, or feeling things that are not there, swelling of the face, fingers, feet, or lower legs, tingling or pain in the fingers or toes when exposed to cold temperatures, Bluish color of the skin of the fingers or toes, continuing or severe abdominal or stomach pain, sores, ulcers, or white spots on the lips or in the mouth, burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings, Bluish color of the fingernails, lips, skin, palms, or nail beds, feeling of constant movement of self or surroundings, loss in sexual ability, desire, drive, or performance, redness or other discoloration of the skin, continuing ringing or buzzing or other unexplained noise in the ears, increased sensitivity of the skin to sunlight, Change in taste or bad, unusual, or unpleasant (after) taste. Depression: what is burnout? Common side effects of metoprolol include: Tiredness Dizziness or lightheadedness Heartburn And one possible symptom of this side effect is sudden weight gain. It also is used to treat chronic (long-term) angina (chest pain). sharing sensitive information, make sure youre on a federal The first images of the 'middle aged' Love Island programme hosted by Davina McCall have been released ahead of the show's launch. Bethesda, MD 20894, Web Policies The pill forms generally are thought to be safe for men with high blood pressure who are otherwise in good health. Mild side effects Serious side effects FAQs Side effects explained Warnings What to ask your doctor Introduction If you have certain heart problems, you may be interested in learning. It is also important information to carry with you in case of emergencies. If dizziness doesnt improve or is severe, talk with your doctor. about Viagra Does Metoprolol Cause ED? You should also avoid drinking alcohol, as this could make dizziness worse. Bisoprolol only comes in a tablet form. government site. Metoprolol is a safe and effective beta-adrenergic medication used to treat a variety of cardiovascular conditions. If I have side effects with metoprolol tartrate tablets, will they likely go away if I switch to metoprolol succinate ER tablets? The use of metoprolol during this time period may have exacerbated his symptoms. A product that may interact with this drug is: fingolimod. a serious heart problem such as heart block, sick sinus syndrome, or slow heart rate; severe heart failure (that required you to be in the hospital); or. Drugs A-Z provides drug information from Everyday Health and our partners, as well as ratings from our members, all in one place. Drug interactions may change how your medications work or increase your risk for serious side effects. Things to remember when you fill your prescription. Metoprolol - metoprolol tartarate 50mg seems to lower my pulse rate a lot. If you have weight changes with metoprolol, especially sudden weight gain, talk with your doctor. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you do, chest pain that is worse and in some cases heart attack may occur. Goldner JA. It works by affecting the response to nerve impulses in certain parts of the body, like the heart. This produces a steady level of metoprolol in your body over the course of the day. A very serious allergic reaction to this drug is rare. Like most drugs, metoprolol can cause an allergic reaction in some people. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. Memory loss wasnt reported in studies of metoprolol succinate extended-release tablets. If you have hallucinations while taking metoprolol, talk with your doctor. What is Prolomet XL 50? Lopressor (metoprolol)." Smoothie. The benefit of treating hypertension may outweigh any risks to the baby. Liu X, Lou X, Cheng X, Meng Y. Familial liability for metoprolol-induced psychosis. Novartis Pharmaceuticals (2001): 2. Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Get medical help right away if you develop chest pain/tightness/pressure, chest pain spreading to the jaw/neck/arm, unusual sweating, trouble breathing, or fast/irregular heartbeat. Drinking alcohol can increase certain side effects of metoprolol. Despite being an effective treatment option, there are risks associated with beta-blocker therapy. This article takes a look at seven home remedies for high blood pressure, including, New research suggests the risk of developing high blood pressure may be higher for women taking oral forms of estrogen than those who take non-oral. These side effects may go away during treatment as your body adjusts to the medicine. Severe allergies. Commonly reported side effects of metoprolol include: cardiac failure, bradycardia, and hypotension. Talk to your pharmacist for more details. The patient was evaluated by a cardiologist after being discharged from the ER. Federal government websites often end in .gov or .mil. Some side effects may not be reported. Metoprolol (Oral Route) Side Effects - Mayo Clinic Drugs and Supplements Metoprolol (Oral Route) Description and Brand Names Drug information provided by: IBM Micromedex US Brand Name Lopressor Toprol XL Descriptions Metoprolol is used alone or together with other medicines to treat high blood pressure (hypertension). This could increase your risk of the drugs side effects. Blood circulation problems. Damage to these organs may cause heart disease, a heart attack, heart failure, stroke, kidney failure, loss of vision, and other problems. Metoprolol is usually taken on a long-term basis for all its uses. If you have a thyroid problem, your doctor may order thyroid function tests more often than usual while youre taking this drug. Learn about diuretics, beta-blockers, ACE inhibitors, calcium channel blockers, and others, High blood pressure thats not well managed can gradually damage your kidneys. Metoprolol succinate is also used to treat heart failure in adults, and high blood pressure in some children. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. Nearly half of U.S. adults have some form of heart disease, according to the American Heart Association's latest statistical update, published in March 2019 in Circulation .The medication metoprolol (Lopressor, Toprol, Toprol XL) is one of the drugs commonly prescribed to treat heart-related concerns, according to the U.S. National Library of Medicine, including: Talk with your doctor about lifestyle changes that may help this medication work better (such as stress reduction programs, exercise, and dietary changes). Commonly reported side effects of metoprolol include: cardiac failure, bradycardia, and hypotension. The most common adverse reactions were tiredness, dizziness, depression, shortness of breath, bradycardia, hypotension, diarrhea, pruritus, and rash.[Ref]. Your condition may become worse when the drug is suddenly stopped. It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. It usually gets better in a few days or weeks as your body adjusts to the drug. It is important that you continue taking metoprolol even if you feel well. Below are answers to some frequently asked questions about metoprolols side effects. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Metoprolol slows down your heart rate. See GoodRx coupons. How it works Metoprolol is a medication that may be used to treat or prevent various heart conditions. But most people taking metoprolol have only minor side effects or none at all. Metoprolol / hydrochlorothiazide is a combination medication that works well to lower your blood pressure. If you have liver problems, metoprolol could build up in your system. Electrocardiogram (EKG) showed sinus rhythm with left anterior fasicicular block. Some products have ingredients that could raise your heart rate or blood pressure or worsen your heart failure. Similar results were found in our case, but we recommend an observational study to find connections between metoprolol use andCNS side effects. Canada residents can call a provincial poison control center. If your doctor determines the problem may be caused by metoprolol, they may recommend switching you to a different treatment for your condition. In our case, the patient reported restless nights and sleep disturbances as well. Side Effects; Products and services. The content published in Cureus is the result of clinical experience and/or research by independent individuals or organizations. Risk factors associated with these side effects are old age, impaired liver function, or pre-existing cognitive deficits [3]. Generic alternatives may be available. "Product Information. Beta-blockers are commonly prescribed to elderly patients for various medical conditions. But its unclear how often this has happened or if the drug was the cause. Liver problems. Theyll likely check your blood pressure. If I take too much metoprolol, what overdose symptoms might I experience. Metoprolol-induced visual hallucinations may be underreported due to several factors, such as inability to connect the symptom to the drug or attribute the hallucinations to dreaming or nightmares [1]. Patients maybe too embarrassed to discuss the symptoms due to the fear it may be confused with mental illness or substance abuse, or physicians may fail to recognize the adverse drug effect and may consider it to be related to a pre-existing medical or psychiatric condition [1]. If your doctor confirms youve had a serious allergic reaction to metoprolol, they may have you switch to a different treatment. Highly lipid-soluble beta-blockers will be quickly and rapidly absorbed in the gastrointestinal tract and metabolized by the liver, and then widely distributed to all tissues [2]. It works by relaxing blood vessels and slowing your heart rate. You should not stop using metoprolol suddenly. They may recommend taking a laxative medication. If youre pregnant or planning to become pregnant, talk with your doctor about the risks and benefits of taking this drug. But its unclear how often this has happened or if the drug was the cause. He wants me to take half in the morning and skip the evening dose for two days, then stop entirely. Remember that many people with high blood pressure do not have any symptoms. Metoprolol can reduce some of the symptoms of low blood sugar, such as a fast heartbeat and tremors. Gliebus G, Lippa CF. However, taking too much metoprolol can cause serious problems including heart failure, heart attack, and death. High blood pressure often has no symptoms. Many medications can be used to treat high blood pressure. (This is known as a drug-condition interaction.) Consumer's Guides: Understand Your Treatments, 87Metoprolol (Metoprolol Tartrate)Reviews, Hypertensive Heart (w/ CHF) and Renal Disease, Hypertensive Heart (w/o CHF) and Renal Disease. As a library, NLM provides access to scientific literature. Do not store in the bathroom. O 0, 3. If your doctor prescribes a low-salt or low-sodium diet, follow these directions carefully. What are the more common side effects of metoprolol? Constipation wasnt reported in studies of metoprolol succinate extended-release tablets. Examples of mild side effects that have been reported with this drug include: If you have symptoms that are ongoing or bother you, talk with your doctor or pharmacist. This medicine is a beta-blocker. You can then share this information with your doctor. The site is secure. The patient was evaluated in an emergency room (ER) six weeks ago for lightheadedness and fatigue. Its also given to prevent chest pain (angina) and improve survival after a heart attack. As you age, your liver and kidneys become less effective at clearing drugs such as metoprolol from your body. If your child cannot eat regularly, is vomiting, or has symptoms of low blood sugar (such as sweating, shaking), tell the doctor right away. Other symptoms of low blood sugar level, such as dizziness and sweating, are not affected by this drug. Keep all appointments with your doctor. But with metoprolol succinate ER tablets, the metoprolol is released into your body slowly as the tablet passes through your digestive system. Note: After the Food and Drug Administration (FDA) approves a drug, it tracks and reviews side effects of the medication. Metoprolol can reduce some of the symptoms caused by high levels of thyroid hormones in your body, such as a fast heartbeat and tremors. Ask your pharmacist any questions you have about refilling your prescription. Call your doctor if you have any unusual problems while taking this medication. On many occasions we may overlook neurological changes as part of the aging process in our elderly patients. Check with your doctor immediately if any of the following side effects occur while taking metoprolol: Get emergency help immediately if any of the following symptoms of overdose occur while taking metoprolol: Some side effects of metoprolol may occur that usually do not need medical attention. What is the mechanism of action and what are this medicine side effects? Severe exacerbation of angina, myocardial infarction and ventricular arrhythmias have been reported in patients with coronary artery disease following the abrupt discontinuation of therapy with beta-blockers. Avoid driving or hazardous activity until you know how this medicine will affect you. Metoprolol is also used to improve survival after a heart attack. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. Common side effects may include: dizziness, tired feeling; depression, confusion, memory problems; nightmares, trouble sleeping; diarrhea; or. Metoprolol Succinate vs Tartrate - What's the difference between them? Slow heart rate. You may also want to check out the online communities at Bezzy. Many people using this medication do not have serious side effects. It works by blocking the action of certain natural chemicals in your body, such as epinephrine, on the heart and blood vessels. Due to this risk, your doctor may prescribe a dosage of metoprolol thats lower than usual. If you feel dizzy while taking metoprolol, sit or lie down until the feeling passes. To prevent chest pain, a second heart attack, or migraine headaches, it is very important to take this medication regularly as prescribed. Bisoprolol is a selective beta blocker that's used to treat high blood pressure. The dosage is based on your medical condition and response to treatment. Ask your pharmacist for a list of the ingredients. The risk of beta-blocker CNS side effects is directly associated with the lipophilic property of the drug. If you notice any problems with your memory while taking metoprolol, talk with your doctor. They have proven to decrease the mortality of cardiovascular conditions, such as CAD and heart failure. However, having high blood pressure during pregnancy may cause complications such as diabetes or eclampsia (dangerously high blood pressure that can lead to medical problems in both mother and baby). What are the mild side effects of metoprolol? If you take metoprolol with certain other medications, especially blood pressure medications, you may have an increased risk of dizziness. Hot or cold packs may also help, as can over-the-counter anti-inflammatory gels. However, for water-soluble beta-blockers, the concentration in the CSF is one-fifth to one-tenth of the plasma concentration [2]. If its too low, they may adjust your dosage of metoprolol or other blood pressure medications you take. You may report side effects to Health Canada at 1-866-234-2345. Banning abortions disproportionately impacts poor women and women of color. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. McAinsh J, Cruickshank JM. Continue reading for a comprehensive list of adverse effects. With metoprolol tartrate IR tablets, all the metoprolol in the tablet is released into your body soon after you take it. It may harm an unborn baby. Allergic reaction. You will need frequent medical tests, and your blood pressure will need to be checked often. If your pulse is faster or slower than it should be, call your doctor. Metoprolol succinate extended-release (ER) tablets and metoprolol tartrate immediate-release (IR) tablets contain the same active ingredient metoprolol. The views expressed in this publication represent those of the author(s) and do not necessarily represent the official views of HCA Healthcare or any of its affiliated entities. Keep all medical and lab appointments. Most people with high blood pressure do not feel sick. . (Note that the different forms have some different uses.). Additionally, doctors may prescribe metoprolol with other medicines to treat heart failure. Some examples of questions you may want to ask your doctor include: To get information on different conditions and tips for improving your health, subscribe to any of Healthlines newsletters. Hallucinations werent reported in studies of metoprolol succinate extended-release tablets. 10. They can then use this information to adjust your treatment plan if needed. The prevalence rates of depression and anxiety in patients with CHF were reported as 10%-60% and 11%-45% during literature review [7]. Examples of these heart conditions include heart block, sick sinus syndrome, shock, and certain kinds of heart failure. Last updated on May 14, 2023. Continue to take metoprolol even if you feel well. The authors have declared that no competing interests exist. Batch CBD Full-Spectrum Gummies. US residents can call their local poison control center at 1-800-222-1222. Talk to your doctor about the possible risks of using this medication for your condition. Careers, Unable to load your collection due to an error. Some people may have hallucinations while taking metoprolol, but this side effect is likely to be rare. In the US - Call your doctor for medical advice about side effects. If they determine the hallucinations may be caused by metoprolol, they may recommend switching you to a different treatment for your condition. Take your next dose at the regular time. The patient was started on metoprolol and amiodarone for postoperative atrial fibrillation following aortic valve replacement nine months ago. Metoprolol may not be right for you if you have certain medical conditions. metoprolol tartrate immediate-release tablets, metoprolol succinate extended-release tablets, swelling under your skin, usually in your eyelids, lips, hands, or feet, swelling of your mouth, tongue, or throat, which can make it hard to breathe, a product you apply to your skin, such as hydrocortisone cream, what dose of the drug you were taking when you had the side effect, how soon you had the side effect after starting that dose, any other information you feel is important. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. Monoamine oxidase inhibitors (MAOIs) Monoamine oxidase inhibitors ( MAOIs) are used to treat depression and Parkinson's disease. If you have severe allergies, for example to foods or insect stings, taking metoprolol could make your allergies worse. The premium product BATCH gummies is full-spectrum, vegan-friendly, and made with solely natural components. Skip the missed dose and use your next dose at the regular time. "Vitamn C njdete v ovoc, ako s pomarane a jahody, a vitamn E v . Limit alcoholic beverages. Metoprolol-induced visual hallucinations: a case series. Serious side effects Along with its needed effects, metoprolol (the active ingredient contained in Metoprolol Succinate ER) may cause some unwanted effects. A study by Burkauskas et al. Keep all medications away from children and pets. They need immediate treatment. And most mild side effects tend to improve with continued treatment as your body gets used to the medication. You may report side effects may occur, this article should not be right for you if you feel while. 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