Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away: Headache. yellowing of the skin or eyes (jaundice) Rare side effects of Itraconazole include: none. This medicine interacts with many other drugs. Call your doctor for medical advice about side effects. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). Serious hepatotoxicity (including some cases of fatal acute liver failure), hepatitis, and reversible increases in hepatic enzymes have also been reported during postmarketing experience. Terms of Use. Take this medication by mouth with food as directed by your doctor, usually once or twice daily. Erectile dysfunction (ED) is often a symptom . To receive this product you must also be at high risk for COVID-19 complications due to older age, obesity, or ongoing medical conditions (such as lung or heart disease or diabetes, among others).. NOTE: This sheet is a summary. Hearing loss. Copyright: Merative US L.P. 1973, 2023. signs and symptoms of heart failure like breathing problems; fast, irregular heartbeat; sudden weight gain; swelling of the ankles, feet; unusually weak or tired. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the . If your symptoms do not improve, or if they become worse, check with your doctor. This content does not have an Arabic version. Swallow the capsule whole and do not crush, chew, break, or open it. Check with your doctor right away if you have stomach pain or tenderness, clay-colored stools, dark urine, decreased appetite, fever, headache, itching, loss of appetite, nausea, vomiting, skin rash, swelling of the feet or lower legs, unusual tiredness or weakness, or yellow eyes or skin. Npoje s vysokm obsahom antioxidantov, ako s vitamny C a E, preukzatene zlepuj erektiln funkciu tm, e brnia pokodeniu buniek, produkujcich oxid dusnat," hovor Pearlmanov. COMMON BRAND NAME(S): ONMEL, Sporanox, TOLSURA. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Copyright 2023 Elsevier Inc. All Rights Reserved. You will need to talk about any risks to your baby. Consult your. Talk to your pediatrician regarding the use of this medicine in children. There are many other drugs that must not be taken with itraconazole oral solution. "Vitamn C njdete v ovoc, ako s pomarane a jahody, a vitamn E v . Have blood work checked as you have been told by the doctor. All rights reserved. For all uses of itraconazole oral solution: This medicine may interact with other drugs or health problems. Runny nose. Do not take itraconazole oral solution if you are pregnant. There may be drug take-back programs in your area. The most common adverse events are gastrointestinal upset, headache, and transient skin reaction. Itraconazole passes into breast milk. Follow all dosing instructions carefully. All rights reserved. Brand name: Sporanox All rights reserved. Do not use avanafil (Stendra), cisapride (Propulsid), disopyramide (Norpace), dofetilide (Tikosyn), dronedarone (Multaq), eliglustat (Cerdelga), eplerenone (Inspra), felodipine (Plendil), irinotecan (Camptosar), isavuconazole (Cresemba), ivabradine (Corlanor), lomitapide (Juxtapid), lurasidone (Latuda), methadone (Dolophine), naloxegol (Movantik), nisoldipine (Sular), oral midazolam (Versed), pimozide (Orap), quinidine (Cardioquin, Quinaglute), ranolazine (Ranexa), ticagrelor (Brilinta), triazolam (Halcion), venetoclax (Venclexta), an ergot medicine (eg, dihydroergotamine, ergometrine, ergotamine, methylergometrine, Cafergot, Ergomar, Wigraine), or certain medicines to lower cholesterol (eg, lovastatin, simvastatin, Mevacor, Zocor) during and 2 weeks after treatment with itraconazole. Store at room temperature away from moisture, heat, and light. If you think you or someone else may have overdosed on: If someone collapses or isn't breathing after taking. Make sure your doctor knows if you are pregnant or planning to get pregnant before you start using this medicine for a fingernail or toenail infection. You may report side effects to FDA at 1-800-FDA-1088. Queens of the Stone Age will bring Phantogram, Viagra Boys, the Armed, and Savages' Jehnny Beth on their fall North American tour. Warning Oral route (Capsule) It may not be safe to breastfeed while using this medicine. Batch CBD Full-Spectrum Gummies. Check with your doctor right away if you have stomach pain or tenderness, clay-colored stools, dark urine, decreased appetite, fever, headache, itching, loss of appetite, nausea, vomiting, skin rash, swelling of the . You may experience dizziness or drowsiness (use caution when driving or engaging in tasks that require alertness until response to drug is known); nausea, vomiting, or diarrhea (small frequent meals, frequent mouth care, sucking lozenges, or chewing gum may help). Lancet 357 (2001): 1766-7, 20. (See box for a list of supplements that should be avoided if you have kidney disease.) Follow all directions on your prescription label and read all medication guides or instruction sheets. This content does not have an Arabic version. All rights reserved. oral midazolam, or triazolam (Valium-like sedatives). Avoid medication errors by using only the brand and strength your doctor prescribes. Uses Warnings Before taking Side effects Interactions Dosage FAQ What is Viagra? WebMD does not provide medical advice, diagnosis or treatment. Additional fungi it has efficacy against include Candida spp, Aspergillus, spp, Cryptococcus spp, Histoplasma spp, and Blastomyces spp. Tell your doctor if you are breast-feeding. Call your doctor or get medical 4 3 3 1. [Ref], Very common (10% or more): Hypertriglyceridemia (up to 11%), Common (1% to 10%): Hypokalemia, hypomagnesemia, hypophosphatemia, increased appetite, Uncommon (0.1% to 1%): Fluid overload, hypocalcemia, anorexia, hyperglycemia, Frequency not reported: Dehydration, decreased weight, hyperkalemia[Ref], Hypertriglyceridemia and hypokalemia have also been reported during postmarketing experience. Tell your doctor if your condition does not get better or if it gets worse. with your doctor, nurse, pharmacist, or other health care provider. "Itraconazole therapy for nonmeningeal coccidioidomysosis: clinical and laboratory observations." Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue. Some items may interact with your medicine. If you notice other effects not listed above, contact your doctor or pharmacist. Mayo Clinic on Incontinence - Mayo Clinic Press, Mayo Clinic on Hearing and Balance - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press, numbness or tingling in the hands, feet, or lips, dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position, muscle cramps in the hands, arms, feet, legs, or face, numbness and tingling around the mouth or fingertips, slow, fast, or pounding heartbeat or pulse, swelling of the fingers, hands, feet, or lower legs, blistering, peeling, or loosening of the skin, bloating or swelling of the face, arms, hands, lower legs, or feet, burning, crawling, itching, numbness, painful, prickling, "pins and needles", or tingling feelings, continuing ringing or buzzing or other unexplained noise in the ears, coughing that sometimes produces a pink frothy sputum, large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or genitals, puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue, red skin lesions, often with a purple center, sores, ulcers, or white spots on the lips or in the mouth, weakness in the arms, hands, legs, or feet, pains in the stomach, side, or abdomen, possibly radiating to the back, feeling of constant movement of self or surroundings, loss in sexual ability, desire, drive, or performance, pain or tenderness around the eyes and cheekbones, increased sensitivity of the eyes or skin to sunlight, redness or other discoloration of the skin. Tell your doctor about the allergy and Call your doctor right away if you have signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach This includes your doctors, nurses, pharmacists, and dentists. Do not drive, use machinery, or do anything that needs mental alertness until you know how the medicine affects you. confusion, a light-headed feeling (like you might pass out); blurred vision, double vision, ringing in your ears, problems with hearing; numbness or tingly feeling, loss of bladder control; little or no urinating, pain or burning when you urinate; headache, dizziness, drowsiness, tiredness; nausea, vomiting, stomach pain, diarrhea, constipation; unusual or unpleasant taste in your mouth. Some brands of itraconazole are not for use in treating fungal infections of the fingernails or toenails. Use this medicine for the full prescribed length of time, even if your symptoms quickly improve. Very bad and sometimes deadly liver problems have rarely happened with itraconazole oral solution. Special care may be needed. Clin Chest Med 30 (2009): 203-15, v. 14. Review/update the Itraconazole is a triazole antifungal drug. Coming to a Cleveland Clinic location?Hillcrest Cancer Center check-in changesCole Eye entrance closingVisitation and COVID-19 information. Cerner Multum, Inc. "Australian Product Information." This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions. Commonly reported side effects of itraconazole include: nausea. Properly discard this product when it is expired or no longer needed. hearing loss a low supply of oxygen rich blood to the heart heart valve disease chronic heart failure absence of stomach acid decreased stomach acid decreased kidney function visible water. For example, increased plasma concentrations of some of these drugs can lead to QT prolongation and ventricular tachyarrhythmias including occurrences of torsades de pointes, a potentially fatal arrhythmia. If it is almost time for your next dose, take only that dose. include protected health information. vomiting, diarrhea, rash, edema, fatigue, dizziness. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). Itraconazole: Side Effects. Incidence (%) (N=602) Gastrointestinal Nausea Vomiting Diarrhea Abdominal Pain Anorexia. Side Effects What are the side effects of Itraconazole (Sporanox)?. Continue to take this medication until the full prescribed amount is finished, even if symptoms disappear after a few days. Do not start, stop, or change the dosage of any medicines without your doctor's approval. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. You may report side effects to the FDA at 1-800-332-1088. 21. information and will only use or disclose that information as set forth in our notice of It may take a few weeks to months to see the full effect. This is not a complete list of possible side effects. Do not skip doses or stop your medicine early. Signs of high blood sugar like confusion, feeling sleepy, more thirst, more hungry, passing urine more often, flushing, fast breathing, or If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. J Am Acad Dermatol 23 (1990): 593-601, 2. If signs or symptoms of congestive heart failure occur or worsen during administration of itraconazole, reassess the benefit and risk of continuing treatment.Drug Interactions:Coadministration of certain drugs that are metabolized by human CYP3A4 enzymes are contraindicated with itraconazole because plasma concentrations of such drugs are increased, which may also increase or prolong both the pharmacologic effects and/or adverse reactions to these drugs.Coadministration with colchicine, fesoterodine, and solifenacin is contraindicated in subjects with varying degrees of renal or hepatic impairment, and coadministration with eliglustat is contraindicated in subjects that are poor or intermediate metabolizers of CYP2D6 and in subjects taking strong or moderate CYP2D6 inhibitors.Increased plasma concentrations of some of these drugs can lead to QT prolongation and/or ventricular tachyarrhythmias, including occurrences of torsades de pointes, a potentially fatal arrhythmia. For example, increased plasma concentrations of some of these drugs can lead to QT prolongation and ventricular tachyarrhythmias including occurrences of torsades de pointes, a potentially fatal arrhythmia. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. Take your next dose at the regular time. Keep taking itraconazole oral solution as you have been told by your doctor or other health care provider, even if you feel well. ciprofloxacin, Augmentin, fluconazole, amoxicillin / clavulanate, nystatin topical, nystatin, clotrimazole topical, clotrimazole, vancomycin, ketoconazole. Sporanox (itraconazole)." Rarely, this medicine may cause severe liver problems. It works by slowing the growth of fungi that cause infection. Copyright 2023 Elsevier Inc. All Rights Reserved. Follow the directions on the prescription label. There have also been rare reports of hepatitis. Check It is very important that your doctor check your progress at regular visits to make sure that this medicine is working properly. Do not take your medicine more often than directed. being able to get an erection, but not having it last long enough for sex. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Keep all drugs out of the reach of children and pets. Alcohol may also increase the risk of serious liver problems. It works by stopping the growth of fungi. Numbness, tingling, or burning pain anywhere in your body. Everyday Health is among the federally registered trademarks of Everyday Health, Inc. and may not be used by third parties without explicit permission. This drug may make you dizzy. Common side effects of itraconazole are skin rash, high liver test results, and digestive system . Curr Ther Res Clin Exp 56 (1995): 1066-75, 3. Esta actitud por parte del paparazzi . Oral fungal infections (thrush) of the mouth and throat Itraconazole (Sporanox) dosage forms Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once. Do not use longer than you have been told. You may report side effects to FDA at 1-800-FDA-1088. If signs or symptoms of congestive heart failure occur during administration of itraconazole capsules, discontinue administration. Call your doctor for medical advice about side effects. Drugs A-Z provides drug information from Everyday Health and our partners, as well as ratings from our members, all in one place. You may get drowsy or dizzy. Do not take double or extra doses. Stop using itraconazole and call your doctor at once if you have signs of congestive heart failure: feeling tired or short of breath, cough with mucus, fast heartbeats, swelling, rapid weight gain, or sleep problems. The oral liquid is best taken on an empty stomach. You may need to take this medicine for several weeks or months before your infection gets better. Am J Health Syst Pharm 58 (2001): 1076, 19. Side effects that you should report to your doctor or health care professional as soon as possible: Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome): This list may not describe all possible side effects. Although not all of these side effects may occur, if they do occur they may need medical attention. It comes as an oral solution that you can take by mouth. Take this medicine on an empty stomach, at least 30 minutes before or 2 hours after food. What home remedies work well for toenail fungus? Janssen Pharmaceuticals (2002): 16. Examples of affected drugs include certain "blood thinners" (such as ticagrelor), colchicine, certain drugs to treat irregular heartbeat (such disopyramide, dofetilide, dronedarone, quinidine), eplerenone, ergot alkaloids (such as dihydroergotamine, ergotamine, methylergonovine), felodipine, fesoterodine, irinotecan, ivabradine, lurasidone, methadone, midazolam, nisoldipine, pimozide, ranolazine, certain "statin" cholesterol drugs (such as lovastatin, simvastatin), solifenacin, telithromycin, triazolam, among others. 9 3. Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver problems, kidney problems, heart problems (such as heart failure, coronary artery disease, heart valve disease), lung disease (such as chronic obstructive pulmonary disease-COPD). It may not cover all possible information. Click here for an email preview. Call your doctor for medical advice about side effects. Check with your pharmacist. 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