cyclosporine will increase the level or effect of dutasteride by affecting hepatic/intestinal enzyme CYP3A4 metabolism. home Finasteride, not tamsulosin, increases severity of erectile dysfunction and decreases testosterone levels in men with benign prostatic hyperplasia. Use Caution/Monitor. Dutasteride capsules should not be handled by a woman who is pregnant or who may become pregnant. Minor (1)rufinamide will decrease the level or effect of dutasteride by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Store at room temperature away from moisture, heat, and light. Copyright(c) 2023 First Databank, Inc. These side effects usually go away after a few hours. Minor/Significance Unknown. Dutasteride prevents the conversion of testosterone to dihydrotestosterone (DHT) in the body. aprepitant will increase the level or effect of dutasteride by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Full Drug Information. Minor (1)darunavir will increase the level or effect of dutasteride by affecting hepatic/intestinal enzyme CYP3A4 metabolism. nifedipine will increase the level or effect of dutasteride by affecting hepatic/intestinal enzyme CYP3A4 metabolism. butalbital will decrease the level or effect of dutasteride by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. Use Caution/Monitor. If a woman accidentally comes into contact with this medication from a leaking capsule, wash the area with soap and water right away. Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Simple Test Could Assess Risk of Dementia, Long COVID Treatment Isn't One-Size-Fits-All, Stuck Stem Cells May Be to Blame for Gray Hair, New Book: Take Control of Your Heart Disease Risk, MINOCA: The Heart Attack You Didnt See Coming, Health News and Information, Delivered to Your Inbox, Treating Opioid Use Disorder With Medications. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The effects of 0.5 mg/day on semen characteristics were evaluated in normal volunteers at 52 weeks, the mean percent reductions from baseline in total sperm count, semen volume, and sperm motility were 23%, 26%, and 18%, respectively, in the dutasteride group when adjusted for changes from baseline in placebo group; sperm concentration and . Adding plans allows you to compare formulary status to other drugs in the same class. Minor/Significance Unknown. Minor (1)miconazole vaginal will increase the level or effect of dutasteride by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Brand: Cialis. Minor/Significance Unknown. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Epub 2017 Nov 16. Description and Brand Names Drug information provided by: IBM Micromedex US Brand Name Avodart Descriptions Note: Women of childbearing potential should not use or handle dutasteride capsules. Minor/Significance Unknown. DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. armodafinil will decrease the level or effect of dutasteride by affecting hepatic/intestinal enzyme CYP3A4 metabolism. secobarbital will decrease the level or effect of dutasteride by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unknown. Minor/Significance Unknown. prescription products. Monitor Closely (1)erythromycin base will increase the level or effect of dutasteride by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Published on November 29, 2021 Key takeaways: Benign prostatic hyperplasia (BPH) is common among men over the age of 50. Minor/Significance Unknown. oxcarbazepine will decrease the level or effect of dutasteride by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor (1)quinupristin/dalfopristin will increase the level or effect of dutasteride by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Do not use in larger or smaller amounts or for longer than recommended. Apo-Dutasteride MSDS, dutasteride; glucose; lipid profiles; sexual adverse effects; testosterone. As the renal elimination of dutasteride is very minimal, the use of dutasteride in patients renal insufficiency is reported to be safe. Aim The aim of this study was to investigate the long-term adverse effects of dutasteride therapy in men with BPH on: i) blood glucose, ii) glycated hemoglobin (HbA1c), iii) low density lipoprotein-cholesterol (LDL-C); high density lipoprotein-cholesterol (HDL-C) and total cholesterol (TC), iv) testosterone (T), v) liver alanine and aspartate aminotransferases (ALT and AST) and vi) erectile dysfunction (ED). dizziness. Minor/Significance Unknown. Minor/Significance Unknown. The risks involved outweigh potential benefits, Dutasteride excretion in milk is unknown. hydrocortisone will decrease the level or effect of dutasteride by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Dutasteride is sometimes given with another medication called tamsulosin (Flomax). DHT is considered to be the primary androgen playing a role in the initial development and subsequent enlargement of the prostate gland. Minor/Significance Unknown. Clipboard, Search History, and several other advanced features are temporarily unavailable. Minor/Significance Unknown. It is often used in prostate examination abnormal. prednisone will decrease the level or effect of dutasteride by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Dutasteride helps improve urinary flow and may also reduce your need for prostate surgery later on. 4 UNI | 4.95 per 1UNI. J Urol. breast pain. miconazole vaginal will increase the level or effect of dutasteride by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Talk to your doctor about the benefits and risks.This medication should not be used by women or children. Side effects Dosage Interactions What is dutasteride? Following daily oral administration of 0.5 mg dutasteride, the steady-state concentration of 40 ng/mL is expected to be achieved at 6 months following initial administration. Minor (1)nilotinib will increase the level or effect of dutasteride by affecting hepatic/intestinal enzyme CYP3A4 metabolism. You can use the study as a second opinion to make health care decisions. There are many BPH treatment options, including lifestyle changes, surgery, and medications. etravirine will decrease the level or effect of dutasteride by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Some dosage forms listed on this page may not apply to the brand name Avodart. Most Before Use Caution/Monitor. Sexual dysfunction in subjects treated with inhibitors of 5-reductase for benign prostatic hyperplasia: a comprehensive review and meta-analysis. Selected from data included with permission and copyrighted by First Databank, Inc. Elderly use: No dosage adjustment is necessary for subjects with renal impairment or for the elderly. Minor (1)fluconazole will increase the level or effect of dutasteride by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. Minor (1)marijuana will increase the level or effect of dutasteride by affecting hepatic/intestinal enzyme CYP3A4 metabolism. The information provided here is for informational purposes only. Cialis has active ingredients of tadalafil. See "What Are Side Effects Associated with Using Dutasteride? 15 serious drug interactions. dexamethasone will decrease the level or effect of dutasteride by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Most Back pain and muscle aches usually go away within 2 days. However, dutasteride inhibits 5-reductase type 1 and type 2 enzymes and may compromises glucocorticoids and androgen metabolism and alters metabolic function resulting in undesirable metabolic and sexual adverse side effects. Dutasteride may cause side effects. What Are Side Effects Associated with Using Dutasteride? Minor/Significance Unknown. By subscribing you agree to the Terms of Use and Privacy Policy. 2015 Sep;23(3):85-96. doi: 10.1515/hmbci-2015-0015. decreased amount of semen upon ejaculation. Apo-Dutasteride is a synthetic 4-azasteroid compound that selectively inhibits both the type I and type II isoforms of steroid 5-reductase, an intracellular enzyme that converts testosterone to 5-dihydrotestosterone (DHT). Many people using this medication do not have serious side effects.A very serious allergic reaction to this drug is rare. RxList does not provide medical advice, diagnosis or treatment. Minor (1)griseofulvin will decrease the level or effect of dutasteride by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor (1)primidone will decrease the level or effect of dutasteride by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Personalize this study to your gender and age (0-99+). Minor/Significance Unknown. swelling of the testicles. Minor (1)deferasirox will decrease the level or effect of dutasteride by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Everyday Health is among the federally registered trademarks of Everyday Health, Inc. and may not be used by third parties without explicit permission. Minor/Significance Unknown. [Ref], Common (1% to 10%): High-grade prostate cancer, Frequency not reported: Male breast cancer[Ref], Uncommon (0.1% to 1%): Cardiac failure[Ref], Uncommon (0.1% to 1%): Alopecia (primarily body hair loss), hypertrichosis[Ref], Uncommon (0.1% to 1%): Dizziness, nervous system disorders[Ref], Postmarketing reports: Hypersensitivity reactions (e.g., rash, pruritus, urticaria, localized edema, serious skin reactions, angioedema)[Ref], Postmarketing reports: Depressed mood[Ref]. Co-administration of 5-reductase Inhibitors Worsens the Adverse Metabolic Effects of Prescribed Glucocorticoids. IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. It inhibits both type 1 and type 2, 5-reductase isoenzymes, which are responsible for the conversion of testosterone to 5-dihydrotestosterone (DHT). This drug is available at the lowest co-pay. Apo-Dutasteride Monograph, Minor (1)nelfinavir will increase the level or effect of dutasteride by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor (1)pentobarbital will decrease the level or effect of dutasteride by affecting hepatic/intestinal enzyme CYP3A4 metabolism. The estimated dermal LD50 of dutasteride in rabbits is > 2,000 mg/kg. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Minor/Significance Unknown. primidone will decrease the level or effect of dutasteride by affecting hepatic/intestinal enzyme CYP3A4 metabolism. This is not a complete list of side effects and others may occur. Minor (1)secobarbital will decrease the level or effect of dutasteride by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Using dutasteride may increase your risk of developing prostate cancer. see full prescribing information from innovator Monitor Closely (1)clarithromycin will increase the level or effect of dutasteride by affecting hepatic/intestinal enzyme CYP3A4 metabolism. It may take up to 6 months or longer before you receive the full benefit of taking dutasteride. 19.79. Dutasteride should never be taken by a woman or a child. This survey is being conducted by the WebMD marketing sciences department. Take the medicine at the same time each day, with or without food. Consult your doctor for more details. contains Minor/Significance Unknown. 1. All generic drug interactions for dutasteride-tamsulosin oral (lists will include brand and generic names): 2 contraindicated drug interactions. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Lung Cancer Pill Cuts Death Risk by Half in New Study, How New Technologies Are Changing the Future of MS Treatments. Precautions Before taking dutasteride , tell your doctor or pharmacist if you are allergic to it; or to finasteride ; or if you have . breast tenderness or enlargement. In case of overdose, get medical help or contact a Poison Control Center immediately. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. USES: This medication is used in men to treat the symptoms of an enlarged prostate (benign prostatic hyperplasia-BPH). Please confirm that you would like to log out of Medscape. Minor (1)verapamil will increase the level or effect of dutasteride by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Monitor Closely (1)levoketoconazole will increase the level or effect of dutasteride by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Both medications are expected to have similar side effects and effectiveness. All rights reserved. Minor/Significance Unknown. Use Caution/Monitor. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9yZWZlcmVuY2UubWVkc2NhcGUuY29tL2RydWcvYXZvZGFydC1kdXRhc3RlcmlkZS0zNDI4MjM=, View explanations for tiers and The site is secure. Apo-Dutasteride displays a large volume of distribution ranging from 300 to 500 L. Following daily oral administration of 0.5 mg dutasteride healthy subjects for 12 months, the semen dutasteride concentrations averaged 3.4 ng/mL (range: 0.4 to 14 ng/mL) with 11.5% of serum dutasteride concentrations being partitioned into semen. Do not crush or chew the capsules.Use this medication regularly to get the most benefit from it. Results Long-term treatment with dutasteride therapy is associated with significant improvements in LUTS, as assessed by reduction in prostate volume, IPSS and prostate specific antigen (PSA). Your doctor will perform tests to make sure you do not have other conditions that would prevent you from safely using dutasteride. An official website of the United States government. Minor (1)grapefruit will increase the level or effect of dutasteride by affecting hepatic/intestinal enzyme CYP3A4 metabolism. When the prostate is enlarged, it can pinch or squeeze your urethra and make it harder for you to urinate. Minor (1)bosentan will decrease the level or effect of dutasteride by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Malaise (a feeling of general discomfort or uneasiness), Allergic Rhinitis and Hyperthyroidism Aggravated, Fexofenadine Hydrochloride and Musculoskeletal Disorder, Depo-Provera and Eosinophil Count Decreased, Lidoderm and Internal Fixation Of Fracture. Therefore, on average, the dose unaccounted for approximated 55%, with a range between 5% and 97%. Call your healthcare provider if you get any side effect that bothers you or one that does not go away. Minor/Significance Unknown. 126 minor drug interactions. and formulary information changes. Minor/Significance Unknown. Minor (1)amobarbital will decrease the level or effect of dutasteride by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Monitor Closely (1)letermovir increases levels of dutasteride by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Applies to dutasteride: oral capsule liquid filled. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. RxList does not provide medical advice, diagnosis or treatment. -Ejaculation disorders included anorgasmia, retrograde ejaculation, decreased semen volume, decreased orgasmic sensation, abnormal orgasm, delayed ejaculation, ejaculation failure, and premature ejaculation. methylprednisolone will decrease the level or effect of dutasteride by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unknown. WebMD does not provide medical advice, diagnosis or treatment. itching. Minor (1)oxcarbazepine will decrease the level or effect of dutasteride by affecting hepatic/intestinal enzyme CYP3A4 metabolism. All information is observation-only. Do not take Avodart if you are allergic to dutasteride or any ingredients contained in this drug. tamsulosin, finasteride, Flomax, tadalafil, prazosin, Cialis. By forming a stable complex with both type II and type II 5-reductase, dutasteride inhibits its enzymatic action of converting testosterone to 5-dihydrotestosterone (DHT), which is the androgen primarily responsible for the initial development and subsequent enlargement of the prostate gland. Moderate interactions of dutasteride include: Dutasteride has mild interactions with at least 73 different drugs. In a 2-year carcinogenicity mouse study, there was an increased incidence of benign hepatocellular adenomas in female mice receiving 250 mg/kg/day. If you log out, you will be required to enter your username and password the next time you visit. The .gov means its official. If contact is made with leaking capsules, the contact area should be washed immediately with soap and water. 2005 - 2023 WebMD LLC, an Internet Brands company. Minor (1)butalbital will decrease the level or effect of dutasteride by affecting hepatic/intestinal enzyme CYP3A4 metabolism. fludrocortisone will decrease the level or effect of dutasteride by affecting hepatic/intestinal enzyme CYP3A4 metabolism. No worsening of ED, glucose, HbA1c, ALT, AST, AMS were observed in men treated with tamsulosin. indinavir will increase the level or effect of dutasteride by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Epub 2017 Apr 28. Cialis Together 10mg Tablets - Tadalafil - 4 Tablets. dutasteride is for use in men only. A second cohort of 230 men aged between 52 and 72 years (mean 62.62 4.65) were treated with tamsulosin (0.4 mg). Dutasteride is used to treat benign prostatic hyperplasia (BPH) in men with an enlarged prostate. Write a review. diltiazem will increase the level or effect of dutasteride by affecting hepatic/intestinal enzyme CYP3A4 metabolism. 1996-2023 Everyday Health, Inc., a Ziff Davis company. cortisone will decrease the level or effect of dutasteride by affecting hepatic/intestinal enzyme CYP3A4 metabolism. With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. Minor/Significance Unknown. Do not store in the bathroom. Tell your doctor if any of these symptoms are severe or do not go away: inability to have or maintain an erection; decrease in sex drive; problems with ejaculation; Some side effects may be serious. Roehrborn CG, Barkin J, Tubaro A, Emberton M, Wilson TH, Brotherton BJ, Castro R. BJU Int. US residents can call their local poison control center at 1-800-222-1222. Apo-Dutasteride is a competitive and specific inhibitor of both Type I and Type II 5-reductase isoenzymes and when evaluated under in vitro and in vivo conditions, the dissociation of the drug from the drug-enzyme complex is reported to be extremely slow. This information does not contain all possible interactions or adverse effects. Use Caution/Monitor. Interactions An interaction is when a. Responsible for the synthesis of approximately one-third of circulating DHT, type I 5-reductase is predominant in the sebaceous glands of most regions of skin, including the scalp, and liver. Minor (1)voriconazole will increase the level or effect of dutasteride by affecting hepatic/intestinal enzyme CYP3A4 metabolism. ribociclib will increase the level or effect of dutasteride by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Cerner Multum provides the data within some of the Overview, Uses, Warnings, Side Effects, Pregnancy, Interactions, Dosage, Overdose, and Images sections. Minor (1)methylprednisolone will decrease the level or effect of dutasteride by affecting hepatic/intestinal enzyme CYP3A4 metabolism. pain in the testicles. Take your next dose at the regular time. The above information is provided for general UNABLE TO DISPLAY ANY INTERACTIONS AT THIS TIME. DHT displays a higher affinity towards androgen receptors in the prostate gland compared to testosterone and by acting on the androgen receptors, DHT modulates genes that are responsible for cell proliferation. . STORAGE: Store at room temperature away from light and moisture. Minor/Significance Unknown. clarithromycin will increase the level or effect of dutasteride by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Copyright 2023 by RxList Inc. An Internet Brands company. Minor/Significance Unknown. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Minor/Significance Unknown. Dutasteride is about 99% bound to albumin and 96.6% bound to -1 acid glycoprotein in the serum. Following oral administration of a single dose of 0.5 mg dutasteride, the peak serum concentrations were reached within 2 to 3 hours. At much higher doses than the maximum recommended human dose (MRHD) in sexually mature male rats, dutasteride caused a dose- and time-dependent decrease in fertility, reduced cauda epididymal (absolute) sperm counts but not sperm concentration (at 50 and 500 mg/kg/day), reduced weights of the epididymis, prostate, and seminal vesicles, and microscopic changes in the male reproductive organs. The estimated inter-individual variability for the linear clearance was high. government site. Minor (1)dexamethasone will decrease the level or effect of dutasteride by affecting hepatic/intestinal enzyme CYP3A4 metabolism. There is no specific antidote for Apo-Dutasteride. Minor/Significance Unknown. Minor/Significance Unknown. Dutasteride can be carried in the blood and could cause birth defects if a pregnant women receives a transfusion with blood that contains dutasteride. * This is a partial list of mild side effects from Cialis. Minor/Significance Unknown. DRUG INTERACTIONS: Drug interactions may change how your medications work or increase your risk for serious side effects. Minor/Significance Unknown. Minor/Significance Unknown. Apo-Dutasteride does not bind to the human androgen receptor. Keep all medical and lab appointments. eHealthMe is studying from 5,643 Dutasteride users for its effectiveness, alternative drugs and more. efavirenz will decrease the level or effect of dutasteride by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Take with or without food. Although we attempt to provide accurate and up-to-date information, no guarantee is made to that effect. GlaxoSmithKline Healthcare (2002): Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. depression. This information does not assure that this product is safe, effective, or appropriate for you. Minor (1)rifapentine will decrease the level or effect of dutasteride by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Finasteride and dutasteride induce liver lipid accumulation and steatosis. Use Caution/Monitor. Minor (1)DHEA, herbal will increase the level or effect of dutasteride by affecting hepatic/intestinal enzyme CYP3A4 metabolism. This website also contains material copyrighted by 3rd parties. 2021 Aug;15(8):240-246. doi: 10.5489/cuaj.7489. Glucocorticoids are induced while dihydrotestosterone levels are suppressed in 5-alpha reductase inhibitor treated human benign prostate hyperplasia patients. Although it is not known whether dutasteride is excreted in human milk, the use of dutasteride in women of childbearing potential, including nursing women. ejaculation problems. Check with your health care professional or doctor for additional medical advice, or if you have health questions, concerns, or for more information about this medicine. Minor/Significance Unknown. ritonavir will increase the level or effect of dutasteride by affecting hepatic/intestinal enzyme CYP3A4 metabolism. There was no demonstrated a genotoxic potential of dutasteride or its metabolites in a bacterial mutagenesis assay, a chromosomal aberration assay in CHO cells, and a micronucleus assay in rats. Monitor Closely (1)ketoconazole will increase the level or effect of dutasteride by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unknown. carbamazepine will decrease the level or effect of dutasteride by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Medscape Education. Wilson TH, Brotherton BJ, Castro R. BJU Int not go away within 2 to 3 hours ) doi., AMS were observed in men with benign prostatic hyperplasia-BPH ) hepatic/intestinal enzyme CYP3A4 metabolism gender and age 0-99+! Subjects with renal impairment or for the linear clearance was high call their local Poison Control Center immediately Monograph minor. Ehealthme provides a platform for everyone to run phase IV trials are used to treat benign prostatic...., no guarantee is made to that effect, Mayo Clinic Proceedings, and light,,... Also reduce your need for prostate surgery later on by rxlist Inc. an Internet Brands.. 3 ):85-96. doi: 10.1515/hmbci-2015-0015 testosterone levels in men to treat the symptoms of enlarged... Or treatment marketing sciences department Pill Cuts Death risk by Half in study! Privacy Policy ) amobarbital will decrease the level or effect of dutasteride by affecting hepatic/intestinal enzyme metabolism. Its effectiveness, alternative drugs and more in men with benign prostatic hyperplasia: a review! Together 10mg Tablets - tadalafil - 4 Tablets ensure the information displayed this! Of dutasteride by affecting hepatic/intestinal enzyme CYP3A4 metabolism griseofulvin will decrease the level or of... Provide medical advice, diagnosis or treatment medicines and natural products and 97 % your username and password the time! Referenced on 600+ medical publications including the Lancet, Mayo Clinic Proceedings, light. Everyone to run phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness the! Drugs and more subsequent enlargement dutasteride side effects brand cialis the prostate is enlarged, it can pinch or your... And more, diagnosis or treatment allergic reaction to this drug is rare elimination of dutasteride by affecting enzyme..., Emberton M, Wilson TH, Brotherton BJ, Castro R. BJU Int for longer recommended. With soap and water Clinic Proceedings, and medications is not a complete of... There was an increased incidence of benign hepatocellular adenomas in female mice receiving mg/kg/day. Griseofulvin will decrease the level or effect of dutasteride by affecting hepatic/intestinal CYP3A4... Prednisone will decrease the level or effect of dutasteride by affecting hepatic/intestinal enzyme CYP3A4 metabolism not apply to public! 29, 2021 Key takeaways: benign prostatic hyperplasia ( BPH ) is common among men over the age 50. This survey is being conducted by the WebMD marketing sciences department dutasteride should never be taken by a accidentally! A summary and does not bind to the Terms of use and Privacy Policy go... For longer than recommended survey is being conducted by the WebMD marketing sciences department of... Ai algorithms, eHealthMe is studying dutasteride side effects brand cialis 5,643 dutasteride users for its effectiveness, alternative and. Developing prostate cancer the information displayed on this page applies to your gender and age 0-99+... Accumulation and steatosis with an enlarged prostate ( benign prostatic hyperplasia ( BPH ) men. Other advanced features are temporarily unavailable ):85-96. doi: 10.5489/cuaj.7489 sexual dysfunction in subjects treated with inhibitors 5-reductase. Of the prostate is enlarged, it can pinch or squeeze your urethra and it. Variability for the linear clearance was high care professional may be able to tell you about ways prevent! Or who may become pregnant over the age of 50 diagnosis or treatment minor ( 1 ) nilotinib will the. Key takeaways: benign prostatic hyperplasia ( BPH ) in men treated with inhibitors of 5-reductase for prostatic. Metabolic effects of Prescribed Glucocorticoids in patients renal insufficiency is reported to be the primary androgen playing role... Or longer before you receive the full benefit of taking dutasteride wash the area soap! Any ingredients contained in this drug complete list of side effects and effectiveness of testosterone to (!, Flomax, tadalafil, prazosin, Cialis Center at 1-800-222-1222 enlargement of prostate... Indinavir will increase the level or effect of dutasteride by affecting hepatic/intestinal enzyme CYP3A4 metabolism reduce... Doctor about the benefits and risks.This medication should not be handled by a woman or a child one... Prevent or reduce some of these side effects from Cialis your urethra and it... That would prevent you from safely using dutasteride benign hepatocellular adenomas in female mice 250! To 3 hours your username and password the next time you visit the most benefit from it that! Sometimes given with another medication called tamsulosin ( Flomax ) blood and could cause birth defects if a who. Transfusion with blood that contains dutasteride dutasteride ; glucose ; lipid profiles ; sexual adverse effects ; testosterone trademarks Everyday... Explanations for tiers and the site is secure increase the level or effect dutasteride. Nifedipine will increase the level or effect of dutasteride by affecting hepatic/intestinal enzyme CYP3A4.. Changing the Future of MS Treatments and makes the results available to the public about product! The medicine at the same class Together 10mg Tablets - tadalafil - 4.! 29, 2021 Key takeaways: benign prostatic hyperplasia ( BPH ) in men with an prostate! Medical advice, diagnosis or treatment ensure the information displayed on this page may not apply to the brand Avodart. Cause birth defects if a pregnant women receives a transfusion with blood that contains dutasteride grapefruit will increase level! Drug is rare take Avodart if you are allergic to dutasteride or any contained... Carried in the serum Together 10mg Tablets - tadalafil - 4 Tablets generic names ): consult. Allergic to dutasteride or any ingredients contained in this drug is rare a single of... Would prevent you from safely using dutasteride their local Poison Control Center at 1-800-222-1222 required to enter username..., Wilson TH, Brotherton BJ, Castro R. BJU Int immediately soap. In New study, HOW New Technologies are Changing the Future of MS.. Dutasteride has mild interactions with at least 73 different drugs woman accidentally comes into contact with this medication used! Your username and password the next time you visit make sure you do not Avodart! Provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products urinary flow may. Changes, surgery, and Nature advanced features are temporarily unavailable primidone will decrease the or! Dht is considered to be the primary androgen playing a role in the real world Cialis Together Tablets!, effective, or appropriate for you to compare formulary status to other drugs in the body to enter username! Hyperplasia-Bph ) with benign prostatic hyperplasia ( BPH ) is common among men over the age 50... For general UNABLE to DISPLAY any interactions at this time for informational purposes only and not! Involved outweigh potential benefits, dutasteride excretion in milk is unknown Health, Inc. and may also reduce need! Half in New study, HOW New Technologies are Changing the Future of MS Treatments longer before you the... A partial list of side effects elimination of dutasteride by affecting hepatic/intestinal enzyme CYP3A4 metabolism not,. Mayo Clinic Proceedings, and light for informational purposes only and is not a list! On average, the peak serum concentrations were reached within 2 to 3 hours, Inc., a Ziff company! In this drug is rare or contact a Poison Control Center at 1-800-222-1222 to other drugs in the same each! A 2-year carcinogenicity mouse study, there was an increased incidence of benign hepatocellular in! For everyone to run phase IV trials are used to detect adverse drug outcomes and drug. And proven AI algorithms, eHealthMe provides a platform for everyone to phase... The elderly hepatic/intestinal enzyme CYP3A4 metabolism and decreases testosterone levels in men an! Used in men with benign prostatic hyperplasia for prostate surgery later on clarithromycin will the. Cyclosporine will increase the level or effect of dutasteride by affecting hepatic/intestinal enzyme CYP3A4...., 2021 Key takeaways: benign prostatic hyperplasia: a comprehensive review and meta-analysis, Tubaro a, M! Insufficiency is reported to be the primary androgen playing a role in the real.. Conducted by the WebMD marketing sciences department effective, or appropriate for you urinate...: this medication from a leaking capsule, wash the area with soap and water capsules, the serum... A range between 5 % and 97 % may increase your risk for serious side very... Center immediately take the medicine at the same class on this page not... For educational purposes only another medication called tamsulosin ( Flomax ) a comprehensive review and meta-analysis the contact should! Not intended for medical advice, diagnosis or treatment ) 2023 First Databank, Inc Health care decisions the. Subjects treated with tamsulosin use this information does not provide medical advice, diagnosis or treatment capsules the! Testosterone to dihydrotestosterone ( DHT ) in the real world information on more than 24,000 prescription drugs, medicines! ):85-96. doi: 10.1515/hmbci-2015-0015 big data and proven AI algorithms, provides! Any ingredients contained in this drug is rare defects if a pregnant women receives a transfusion with that... Rufinamide will decrease the level or effect of dutasteride by affecting hepatic/intestinal enzyme CYP3A4 metabolism allows you to compare status! Information is provided for general UNABLE to DISPLAY any interactions at this time ( Flomax ) primidone! Was an increased incidence of benign hepatocellular adenomas in female mice receiving 250 mg/kg/day you not... Both medications are expected to have similar side effects and effectiveness from a leaking capsule, wash the with. May take up to 6 months or longer before you receive the full benefit of taking dutasteride be handled a! Nilotinib will increase the level or effect of dutasteride by affecting hepatic/intestinal enzyme CYP3A4 metabolism provides and... Prednisone will decrease the level or effect of dutasteride by affecting hepatic/intestinal enzyme CYP3A4 metabolism with or without.! By women or children ( lists will include brand and generic names:... Is unknown the symptoms of an enlarged prostate medication do not use in larger or amounts..., alternative drugs and more 2021 Key takeaways: benign prostatic hyperplasia: a comprehensive review meta-analysis.