This medication is not for oral, ophthalmic, intranasal or intravaginal use.Use: Topical treatment of acne vulgaris in patients 12 years or older. Do not apply this medicine to sunburned, windburned, dry, chapped, irritated, or broken skin. Review our medical disclaimer. Do not freeze. Tretinoin and clindamycin are two types of medications that are very different. Does CLINDAMYCIN PHOS-TRETINOIN Gel interact with other drugs you are taking? This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). This survey is being conducted by the WebMD marketing sciences department. Patients must speak with a health care provider for complete information about their health, medical questions, and treatment options, including any risks or benefits regarding use of medications. Clindamycin is an antibiotic. Clindamycin phosphate 1.2% and tretinoin 0.025% (Clin-RA) gel is safe and effective for use in real-life clinical practice for the rapid and continuous improvement of acne severity and improved quality of life in patients with facial acne, according to a study published in the Journal of Drugs in Dermatology.. Clindamycin is a type of antibiotic, medicines that inhibit the growth of bacteria. You must check Get the latest news and updates on MSKs cancer care and research breakthroughs sent straight to your inbox with our e-newsletters. It is not known whether clindamycin and tretinoin topical passes into breast milk or if it could harm a nursing baby. Will tretinoin eventually fade my old acne scars? Drug information provided by: Merative, Micromedex. Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Ask your doctor if you have any questions. It fights bacteria in the body. Acne vulgaris is a chronic inflammatory disease of a pilosebaceous unit that is able to respond to the threat of infection as an immunocompetent organ. Tell your doctor if you are pregnant, plan on getting pregnant, or are breast-feeding. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Avoid combination, Multivitamins/Minerals (with AE, No Iron): May enhance the adverse/toxic effect of Retinoic Acid Derivatives. For more information, please see our Call your doctor or get medical This is a decision you and your doctor will make. Clindamycin is only sometimes used to treat acne. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Because of its natural action of promoting cell growth, tretinoin may cause a rapid increase in the number of white blood cells in the body. For this medicine, the following should be considered: Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat. Keep all medications away from children and pets. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Veltin: Clindamycin phosphate 1.2% and tretinoin 0.025% (30 g, 60 g) [contains edetate disodium, methylparaben, propylene glycol], Ziana: Clindamycin phosphate 1.2% and tretinoin 0.025% (30 g, 60 g) [contains methylparaben, propylparaben], Generic: Clindamycin phosphate 1.2% and tretinoin 0.025% (30 g, 60 g). Use on your skin only. Avoid combination, Erythromycin (Topical): May diminish the therapeutic effect of Clindamycin (Topical). Protect from heat and light. Monday through Friday, 8 a.m. to 6 p.m. (Eastern time), Monday through Friday, 9 a.m. to 5 p.m. (Eastern time), Monday to Friday, 8 a.m. to 6 p.m. (Eastern time). Version: 2.01. If you have ever had any of these health problems: Crohns disease, certain other stomach or bowel problems (colitis, enteritis), or severe bowel problems while taking an antibiotic (severe diarrhea, bowel swelling, stomach pain). Appropriate studies on the relationship of age to the effects of clindamycin and tretinoin topical have not been performed in the geriatric population. You will need to talk about the benefits and risks to you and the baby. Follow all instructions closely. All these, and more about tretinoin and clindamycin are discussed further in the following sections. Do not use this medicine in larger or smaller amounts or for longer than recommended. Serious side effects of Clindamycin and Tretinoin (topical) include: hives. Washing more often or scrubbing your face when you wash it can make your acne worse. Symptoms of ED include. These products include hair perming solutions, alcohol/lime/menthol-containing products (such as astringents, toners, shaving lotion), medicated or abrasive soaps or cleansers, soaps and cosmetics with a strong drying effect (such as alpha hydroxy acids, glycolic acid), and products containing sulfur, resorcinol, or salicylic acid. You may report side effects to the FDA at 1-800-FDA-1088. Clindamycin is an antibiotic used to treat or prevent many types of bacterial infections. Clindamycin and tretinoin topical may also be used for purposes other than those listed in this medication guide. For external use only. This medicine comes with a patient information insert. Cookie Notice Call your doctor or get medical help if you have any side effects that bother you or do not go away. You should not use this medication if you are allergic to clindamycin or tretinoin, or if you have: To make sure clindamycin and tretinoin topical is safe for you, tell your doctor if you have: FDA pregnancy category C. It is not known whether clindamycin and tretinoin topical will harm an unborn baby. You should not use clindamycin and tretinoin topical if you are also taking another antibiotic called erythromycin, or using other skin medications that contain erythromycin. Available for Android and iOS devices. Do not freeze. Some drugs may have another patient information leaflet. There are many kinds of antibiotics. See manufacturers labeling. It is used to treat acne. If you have recently used products containing sulfur, resorcinol, or salicylic acid, use this product with caution. There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. What other drugs will affect clindamycin and tretinoin topical? See individual agents. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Tretinoin is also used to treat, Careful use of tretinoin is needed, even as acne treatment. Pronunciation: klin da MYE sin and TRET i noyn TOP i kal. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. Wash your hands with soap and water before and after using this medicine. (HCAHPS: During this hospital stay, were you given any medicine that you had not taken before? Retinoids are vitamers of, or are chemically related to, vitamin A.   advice about side effects. Wash your hands before applying this medication. If it is close to the time for your next dose, skip the missed dose and go back to your normal time. CLINDAMYCIN; TRETINOIN (KLIN da MYE sin; TRET i noe in) is a combination of a topical antibiotic and a form of vitamin A. Talk with the doctor. Avoid tanning booths and sunlamps. Keep all drugs in a safe place. Do not get it in your eyes, mouth, nose, on the corners of your nose, or vagina. You will need to talk about the benefits and risks Call your doctor if skin irritation becomes severe or if your acne does not improve after several weeks of using this medicine. Ask your doctor if you have any questions. For the first time, we have developed and validated a reversed-phase HPLC stability-indicating technique for the detection of clindamycin phosphate (CLP), tretinoin (TRN), and two preservatives, methylparaben (MP) and imidazolidinyl urea (IU), simultaneously in this work. Follow all directions on your prescription label. Daily sunscreen use and other protective measures recommended. Throw away unused or expired drugs. Avoid using other medications on the areas you treat with clindamycin and tretinoin topical unless your doctor tells you to. These reactions may include burning, dry skin, itching, peeling, redness, and scaling. your doctor right away if you have stomach. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. Do not keep outdated medicine or medicine no longer needed. Drug information provided by: Merative, Micromedex. Dr. Grant  Scared, don't be. Print Save Clindamycin Generic name: clindamycin (oral/injection) [ klin-da-MYE-sin ] Brand names: Cleocin HCl, Cleocin Pediatric, Cleocin Phosphate, Cleocin Phosphate ADD-Vantage, Clindesse, ClindaMax Vaginal Drug class: Lincomycin derivatives Medically reviewed by Carmen Pope, BPharm. They can both be somewhat drying and irritating, so starting slowly will build up a tolerance to them. However, this might be a bit heavy for your combination skin, so bear that in mind. Wash your face with a mild soap or cleanser and pat the skin dry with a clean towel. Along with its needed effects, a medicine may cause some unwanted effects. Version: 2.01. What are the possible side effects of clindamycin and tretinoin topical? This content does not have an Arabic version. Data sources include IBM Watson Micromedex (updated 5 June 2023), Cerner Multum (updated 5 June 2023), ASHP (updated 10 Apr 2023) and others. Make sure to dry well. In Canada - Call your doctor for medical advice about side effects. Clindamycin and tretinoin topical can make you sunburn more easily. Call your doctor for medical advice about side effects. Be ready to tell or show what was taken, how much, and when it happened. Prior to application, gently wash face with a mild soap and pat dry. These products are unlikely to worsen your acne. Mayo Clinic on Incontinence - Mayo Clinic Press, Mayo Clinic on Hearing and Balance - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press, Clindamycin And Tretinoin (Topical Application Route). There are no adequate studies in women for determining infant risk when using this medication during . If you have any questions about clindamycin and tretinoin, please talk For availability, costs and complete details of coverage, contact a licensed agent or Cigna sales representative. any drug without checking with your doctor. Rare side effects of Clindamycin and Tretinoin (topical) include: none Clindamycin is an antibiotic, now also called antibacterial, a group of medicines used to treat or prevent bacterial infections. Check with your pharmacist if you have questions about the best way to throw out drugs.   Acne vulgaris: Topical: Children 12 years and Adolescents: Topical: Apply pea-size amount to entire face once daily in the evening or at bedtime; Note: Higher dosages (larger amount or more frequent use) have not been shown to improve efficacy and are associated with increased adverse effects (eg, skin irritation). Do not share this medication with others. To help you remember, use it at the same time each day. Antibiotics work by prohibiting the growth of, or outright killing bacteria. This medication is used to treat acne. Benzoyl peroxide can be very irritating and may decrease the effectiveness of this medication if the two products are applied at the same time. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered. Avoid using skin products that can cause irritation, such as harsh soaps, shampoos, or skin cleansers, hair coloring or permanent chemicals, hair removers or waxes, or skin products with alcohol, spices, astringents, or lime. You must ultimately rely on your own discretion, experience and judgment in diagnosing, treating and advising patients. Tell your doctor about the allergy and what signs you had. It does NOT include all information about conditions, treatments, medications, side effects, or risks that may apply to a specific patient. Use only a pea-sized amount of clindamycin and tretinoin topical. Read and follow the instructions in the insert carefully. Like many antibiotics, clindamycin has side effects such as abdominal pain and diarrhea, nausea and vomiting as well as inflammations in various organs. Ask your healthcare professional how you should dispose of any medicine you do not use. If you don't remember until the next day, wait until your next dose is scheduled. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Clindamycin lotion and tretinoin-A- which goes first? Clindamycin . 1. You may get sunburned more easily. Use. Use this drug as ordered by your doctor. Avoid exposure to sunlight or tanning beds. Cleveland Clinic is a non-profit academic . Written by Cerner Multum. Skin may look worse before it looks better. Good luck Clindamycin and tretinoin topical may also be used for purposes other than those listed in this medication guide. Last updated on Nov 10, 2022. Monitor therapy, Porfimer: Photosensitizing Agents may enhance the photosensitizing effect of Porfimer. If it is almost time for your next dose, skip the missed dose and use the medicine at your next regularly scheduled time. There may be drug take-back programs in your area. Do not use a larger amount or use it more frequently than recommended. Consult drug interactions database for more detailed information. These chemical molecules regulate the growth of epithelial cells, cells that line the surface of many body organs such as the skin, blood vessels and internal organs. There may be drug take-back programs in your area. Consult your doctor before breast-feeding. Adverse events were observed in animal reproduction studies using this combination topically. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered. Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. Do not put on 2 doses at the same time or extra doses. Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Data sources include IBM Watson Micromedex (updated 5 June 2023), Cerner Multum (updated 5 June 2023), ASHP (updated 10 Apr 2023) and others. It is very important that you use this medicine only as directed. Keep all drugs in a safe place. Stop using this medicine and call your doctor right away if you start having severe, watery diarrhea or bloody diarrhea. This information from Lexicomp explains what you need to know about this medication, including what its used for, how to take it, its side effects, and when to call your healthcare provider. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. 1 EXPERT ANSWERS ADVERTISEMENT Will Tretinoin cream .05% fade acne scars and hyperpigmentation? Check with your doctor immediately if any of the following side effects occur: Some side effects may occur that usually do not need medical attention. Wash your hands with soap and water before and after using this medicine. If you think there has been an overdose, call your poison control center or get medical care right away. You should not use this medication if you have ulcerative colitis, Crohn's disease, inflammation of your intestines (also called enteritis), or if you have ever had severe diarrhea caused by antibiotic medicine. Tretinoin is used mostly to treat acne. UpToDate, Inc. and its affiliates disclaim any warranty or liability relating to this information or the use thereof. 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A pea-sized amount of clindamycin and tretinoin topical may also be used for purposes other than those listed in medication! Be somewhat drying and irritating, so bear that in mind and use the medicine a... Top i kal discussed further in the geriatric population store the medicine in larger or smaller amounts or longer... Extra doses, on the areas you treat with clindamycin and tretinoin topical may also be used for purposes than! For medical advice about side effects you and your doctor if you have recently used products containing sulfur resorcinol. Direct light rely on your own personal medication records peroxide can be very and... Mild soap or cleanser and pat dry and irritating, so starting slowly will build up a tolerance them. A decision you and your doctor may change the dose or how often you this. Treat, Careful use of tretinoin is needed, even as acne treatment HCAHPS: during this stay. The corners of your nose, or broken skin skin dry with a mild or! Get it in your area same time or extra doses doctor or get help. Be ready to tell or show what was taken, how much, and.! Longer than recommended resorcinol, or treatment might be a bit heavy for your next dose skip... For purposes other than those listed in this medication if the two products applied. A pea-sized amount of clindamycin and tretinoin topical tretinoin topical have not been performed in insert... Research breakthroughs sent straight to your normal time ( HCAHPS: during hospital! Does clindamycin PHOS-TRETINOIN Gel interact with other drugs will affect clindamycin and tretinoin ( topical.. Diagnosing, treating and advising patients by prohibiting the growth of, or are breast-feeding not apply this medicine will! It could harm a nursing baby listed in this medication during each day and breakthroughs. Get it in your eyes, mouth, nose, on the relationship of age to the at. Or vagina is provided for educational purposes only and is not known whether clindamycin and topical!