Also tell them about any vitamins, herbs, and supplements you use. Transfusion of fresh platelets if bleeding is an issue postoperatively (6). If you have hyperkalemia, your doctor may reduce your dose of spironolactone until your potassium level returns to normal. On the other hand, if spironolactone isnt working well to treat these conditions, your body may retain more fluid. Spironolactone can sometimes cause kidney problems. One of the more common side effects of spironolactone oral tablets is gynecomastia, which is breast growth in males. There are no specific recommendations for older adult dosing. New York Heart Association (NYHA) class 3 or 4, American Association for the Study of Liver Diseases, angiotensin converting enzyme (ACE) inhibitors, Spironolactone expiration, storage, and disposal, How people with type 2 diabetes may benefit from afternoon exercise, Medicare reimbursements differ between simple and complex cataract surgeries, Chronic insomnia may increase stroke risk. StatPearls. Tell your doctor or pharmacist if you're taking any other medicines, including herbal remedies, vitamins or supplements. Spironolactone oral tablets are FDA-approved to treat certain forms of heart failure in adults. Gastrointestinal disorders, neuropsychological disorders and bradycardia are warning signs. Or, they may ask you to take it in two or more doses, broken apart over the day. Your doctor will recommend the right dosage of spironolactone for your condition. Spironolactone is usually not prescribed for male* pattern baldness. Or they may switch you to a different medication. Banning abortions disproportionately impacts poor women and women of color. Spironolactone and its metabolites may interfere with digoxin radioimmunoassay or alter the pharmacokinetics of digoxin. Despite this lack of research, this drug should be used during pregnancy only if the potential benefit justifies the potential risk. Too much aldosterone can be an indicator of a variety of medical conditions. Females with this type of hair loss may also have hirsutism, which is male pattern hair growth. High blood pressure doesnt usually cause symptoms. You should not need a new prescription for this medication to be refilled. Different interactions can cause different effects. Lisinopril oral tablet is a generic prescription drug used for hypertension, heart failure, and heart attack. But when you stop taking spironolactone it will quickly stop working to manage your condition. Spironolactone also lowers your blood pressure. All generic drug interactions for digoxin oral (lists will include brand and generic names): 40 serious drug interactions. Spironolactone can potentially interfere with a specific type of blood test for digoxin levels. This medication isnt approved for use in children younger than 18 years. Alcohol could also increase your risk of low blood sugar. If you have unused medication that has gone past the expiration date, talk with your pharmacist about whether you might still be able to use it. Is digoxin safe to take? And in people with heart failure, treating edema also makes it easier for their heart to pump blood. Digoxin (Lanoxin) is used to treat heart failure and heart rhythm problems. Manufacturer advises avoid or monitor. Call 911 or your local emergency number if your symptoms feel life threatening or if you think youre having a medical emergency. Who may not be able to take spironolactone Spironolactone is not suitable for some people. Your doctor may have you take this as a single dose in the morning. * The drug could also cause hormone problems in a female fetus exposed to the drug. Not all of the alternatives available for treating the same conditions as spironolactone are included. Spironolactone oral tablets are an effective treatment for edema thats caused by cirrhosis and nephrotic syndrome. They may suggest a different form of the drug. When you have low levels of albumin, excess fluid leaks out of your blood vessels into other tissues. * Blood pressure is measured in mmHg. Spironolactone oral tablets are used to treat certain forms of the following conditions: To learn more about these conditions and the situations when spironolactone is used for them, see the Spironolactone uses section above. Emotional side effects werent reported in people who took spironolactone during clinical studies. Examples of other drugs that may be used to treat high blood pressure include: Examples of other drugs that may be used to treat heart failure include: Examples of other drugs that may be used to treat edema (fluid retention and swelling) in people with certain kidney and liver problems include: Examples of other drugs that may be used to treat hyperaldosteronism (a condition in which your adrenal glands make too much of the hormone aldosterone) include: As with all medications, the cost of spironolactone oral tablets can vary. (Your blood carries oxygen.) With this condition, you have hair loss thats caused by too much of the hormone testosterone in your body. Higher lithium levels can potentially lead to toxic effects. But you may be familiar with it for other off-label uses, like acne and hair problems. If your adrenal glands produce too much aldosterone, your kidneys keep more fluid and sodium in your blood than usual. The drug will have its greatest effect in your body during this time. They help your body to get rid of excess fluid through your urine. You can take other diuretics (such as, other medicines that increase your potassium levels. amlodipine, lisinopril, metoprolol, furosemide, carvedilol, spironolactone, propranolol, diltiazem, Xarelto, rivaroxaban. Next review due: 6 July 2025, Taking spironolactone with other medicines and herbal supplements, other diuretics do not take diuretics that increase potassium levels (such as amiloride) with spironolactone. Some NSAIDs, like celecoxib (Celebrex), are only available with a prescription. Moore, N., et al. Heart failure also causes fluid to build up in your lungs, legs, and abdomen (belly). Acebutolol Diltiazem is predicted to increase the risk of cardiodepression when given with Acebutolol. They may recommend that you stop breastfeeding or suggest a different medication for your condition. Below is a list of medications that can interact with spironolactone oral tablets. Blood pressure medications help prevent serious complications, such as stroke and heart disease. Your doctor will ultimately prescribe the smallest dosage that provides the desired effect. But its still important to contact them right away if symptoms of lithium toxicity develop. Examples of possible off-label uses of spironolactone are discussed below. A generic drug is an exact copy of the active drug in a brand-name medication. Spironolactone oral tablets are meant to be swallowed whole. This helps prevent others, including children and pets, from taking the drug by accident. Aldactone (spironolactone) tablets for oral use. They can give you tips on how to deal with any side effects that may be concerning or bothersome. The usual starting dosage of spironolactone for heart failure is 25 mg taken once per day. Your doctor may adjust your dosage as needed during treatment. If youre taking spironolactone for edema related to cirrhosis, youll start this treatment in a hospital. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. Tell them about all prescription, over-the-counter, and other drugs you take. With class 3 heart failure, symptoms such as fatigue, shortness of breath, and palpitations significantly limit your physical ability. Studies have determined the dosages that help keep an effective level of the drug in the body for the different conditions spironolactone treats. For information about the difference between sex and gender, see this article. This side effect could also affect someone who was assigned female at birth but has a certain level of testosterone in their body. To learn more about the cost of spironolactone, refer to this article. Hypertension is called the silent killer because there are often no symptoms as it progresses, leading to more serious disease. They can help you decide if this or another treatment is right for you. Many of these interactions can be managed with safer alternatives, dosage changes, or monitoring. Our website services, content, and products are for informational purposes only. But its still important to let them know if you develop hyperkalemia symptoms. Spironolactone may worsen kidney function in patients with low to no salt in their body or in those who take other blood pressure medicines (eg, ARB, ACE inhibitor). Talk with your doctor if you breastfeed your child. Dangerously high potassium levels. Its also used to treat high blood pressure, heart failure, and excessive aldosterone secretion. Depending on the interaction, you may be more likely to experience side effects. While you take spironolactone, your doctor will order blood tests on a regular basis to check the health of your kidneys. This article provides several useful tips on medication disposal. Theyll typically recommend that you switch to a medication other than spironolactone for your condition. Severity: Moderate Evidence: Study Acebutolol How Do You Look for Drug. What is Spironolactone? This can cause serious worsening of kidney and liver disease. The premium product BATCH gummies is full-spectrum, vegan-friendly, and made with solely natural components. This means alcohol could make Ozempic not work as well as usual. But if you have certain side effects from spironolactone, drinking alcohol could make this worse. But if youre ever concerned about an interaction, contact your healthcare provider or pharmacist. There are many other medications that can also increase potassium levels. home Store spironolactone at room temperature between 68F and 77F (20C and 25C). If your lithium levels are too low, the medication may not work as well for you. If digoxin dose needs to be adjusted, monitor the person carefully for signs of an enhanced or reduced digoxin effect. If you would like to notify the FDA about a side effect youve had with spironolactone oral tablets, you can do so through MedWatch. This drug may be taken as part of a combination therapy with other medications. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Or they may have you take it as several doses throughout the day. Heart failure causes various symptoms that can make everyday activities difficult. RxList does not provide medical advice, diagnosis or treatment. Spironolactone oral tablets can cause mild and serious side effects. View interactions for: Furosemide; Spironolactone; Medicinal forms. It also makes your kidneys filter too much potassium out of your blood. Most diuretics also cause your kidneys to get rid of potassium. Instead, your doctor will prescribe the lowest dosage that best manages your blood pressure and potassium level. As their names suggest, these products all contain potassium. Spironolactone is a potassium sparing diuretic like eplerenone that competitively inhibits mineralocorticoid receptors in the distal convoluted tubule to promote sodium and water excretion and potassium retention. Never try to catch up by taking two doses at once. And this leads to a low potassium level. Its not known how often this side effect occurs. 8 Spironolactone was originally developed purely for this ability before other pharmacodynamic properties of . Mild side effects* of spironolactone oral tablets can include: Most of these side effects may go away within a few days or a couple of weeks. This drug can be taken with or without food. Always discuss possible side effects with a healthcare professional who knows your medical history. Weight loss and weight gain werent reported in people who took spironolactone during clinical studies. Kidney problems are more likely if you take spironolactone with other medications that can cause kidney problems. This causes swelling, which usually first develops around the eyes, followed by the lower legs. If youre interested in this option, check with your doctor or your insurance company. The current stance of the Food and Drug Administration (FDA) is to avoid using expired medications. It can interact with many medications, including spironolactone. The spironolactone oral tablet dosage your doctor prescribes will depend on several factors. Serious side effects from spironolactone oral tablets arent common, but they can occur. How a drug works is called its mechanism of action. Spironolactone shouldnt usually be taken during pregnancy, unless theres no suitable alternative treatment to be used. Spironolactone may be prescribed for androgenic alopecia in females. UNABLE TO DISPLAY ANY INTERACTIONS AT THIS TIME. (2022). This can include setting an alarm or timer on your phone or downloading a reminder app. This drug belongs to a group of drugs called aldosterone antagonists (blockers), or potassium-sparing diuretics. Examples of alternatives for the conditions spironolactone treats are listed below. Spironolactone isnt a blood thinner. By blocking the action of aldosterone, spironolactone makes your kidneys get rid of more sodium and water in your urine. Combining an ACE inhibitor or ARB with spironolactone isnt uncommon. A kitchen timer can work, too. Spironolactone oral tablets arent approved for use in children. (2020). Available for Android and iOS devices. Spironolactone oral tablets have a half-life of 1.4 hours. About digoxin. Omeprazole can interact with medications that need acid to be absorbed. This fluid buildup is called edema. The significance of these interactions isnt fully known. * The drug is not recommended for treating acne in males.*. We comply with the HONcode standard for trustworthy health information. 2023 Healthline Media LLC. Do not take more spironolactone oral tablets than your doctor recommends. Its important that you take your medication every day as directed by your doctor. As with most drugs, some people can have an allergic reaction after taking spironolactone oral tablets. Persistent pulmonary hypertension occurs in newborns when a baby's circulation system doesn't work properly at birth. But if your symptoms are severe, call 911 or your local emergency number, or go to the nearest emergency room right away. This is because the medication could cause sudden changes in the balance of fluid and electrolytes in your body. Manufacturer advises monitor. How to tell the drug is working: You may not be able to tell whether this drug is working or not. For example, its included as a treatment option for ascites due to cirrhosis in guidelines from the American Association for the Study of Liver Diseases. Generic drugs usually cost less than the brand-name version. Call your doctor right away if you have serious side effects. Whats more, this combination can also increase the risk of kidney damage and stomach bleeds. So, your healthcare provider may need to use a different test if youre taking this combination. Its typically recommended to avoid NSAIDs if you have heart failure or high blood pressure. If approved by your insurance company, getting a 90-day supply of the drug could reduce your number of trips to the pharmacy and help lower the cost. Spironolactone [package insert]. Spironolactone may interact with other medications, angiotensin-converting enzyme (ACE) inhibitors, Important considerations for taking spironolactone, dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=0fed2822-3a03-4b64-9857-c682fcd462bc&type=display, jaad.org/article/S0190-9622(20)30510-7/fulltext, link.springer.com/article/10.1007/s13555-020-00481-w, nctr-crs.fda.gov/fdalabel/services/spl/set-ids/3b60de71-2afa-4922-ba3e-0664c2ae29a0/spl-doc, jaad.org/article/S0190-9622(15)02614-6/fulltext, Everything You Need to Know About High Blood Pressure (Hypertension), Oral Estrogen May Raise Your Risk of Hypertension by 19% Compared to Other Forms of Hormone Replacement Therapy, Hypertension Is Known as the Silent Killer, and Heres What You Need to Know, What Parents Need to Know About Persistent Pulmonary Hypertension of the Newborn. Your healthcare provider will monitor your lithium levels during treatment. Off-label drug use means a drug is used for a purpose other than what its been approved for by the FDA. This helps to treat edema (fluid retention and swelling). These are available for purchase at most pharmacies. This is sometimes called potassium salt. Some people with high blood pressure use it in place of regular salt to lower their sodium intake. A look at the possible uses of 3D printers for eye care, Blood pressure medications: Options and side effects, blistering and peeling inside your mouth or nose, or on your eyes or genitals, tingling or numbness in your hands or feet, swelling under your skin, typically in your eyelids, lips, hands, or feet, swelling of your tongue, mouth, or throat, the type and severity of the condition youre treating, if you have certain side effects with this medication, 140/90 millimeters of mercury (mmHg)* or higher, have a high risk for cardiovascular disease due to factors such as diabetes, treating the underlying problem thats causing the nephrotic syndrome, using other diuretics besides spironolactone, for short-term management of symptoms before surgery is done to treat the condition. This makes it easier for your heart to pump blood around your body and supply oxygen to your organs. Its recommended in treatment guidelines from the Endocrine Society for this condition. If you have insurance, youll also need to check whether your plan will cover Aldactone. It affects how much water, sodium, and potassium get filtered out of your blood by your kidneys. To learn more, visit their sites. Enter other medications to view a detailed report. A generic drug is considered to be as safe and effective as the original drug. Spironolactone is a diuretic medication. You can unsubscribe at any time. Fish Oil (omega-3 polyunsaturated fatty acids), Email this report to a friend, doctor, or patient. If you miss a dose of spironolactone oral tablets, take the missed dose as soon as possible. Some medicines affect spironolactone and stop it working properly or increase the chances of you having side effects. Eating lots of potassium-rich foods, especially salt substitutes that contain potassium, also increases your risk for hyperkalemia. Note: The Food and Drug Administration (FDA) tracks side effects of drugs it has approved. Spironolactone can interact with several medications. It is also used alone or with other medications to treat high blood pressure. El paparazzi obstruye la instruccin del caso de espionaje a famosos que ha acabado con . Examples include some medicines that help to prevent blood clots, such as enoxaparin, and some antibiotics, such as, ACE inhibitors, used to treat high blood pressure and heart failure, such as, painkillers known as non-steroidal anti-inflammatory drugs (. And they can advise if another medication or supplement is safe to take. With off-label use, doctors prescribe a drug for a purpose other than what its approved for. Side effects. digoxin oral brand names and other generic formulations include: Cardoxin Oral, Digitek Oral, Digox Oral, Lanoxicaps Oral, Lanoxin Oral. Always speak with your healthcare professional about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking. El paparazzi Gustavo Gonzlez a la polica: "Discos duros, s. When youll need to take spironolactone depends on the dosage youve been prescribed. Aldosterone is a chemical made by the body that can cause water retention. spironolactone oral brand names and other generic formulations include: Check for more interactions with the Drug Interaction Checker, Never use this combination of drugs because of high risk for dangerous interaction, Potential for serious interaction; regular monitoring by your doctor required or alternate medication may be needed, Potential for significant interaction (monitoring by your doctor is likely required), Interaction is unlikely, minor, or nonsignificant. It also helps keep the drug from harming the environment. Spironolactone oral tablets are FDA-approved to treat primary hyperaldosteronism in adults. Spironolactone can sometimes cause sexual problems, such as reduced sex drive and erectile dysfunction. But be sure to take the dosage your doctor prescribes for you. Paxlovid (nirmatrelvir/ritonavir) is an oral antiviral medication that's authorized to treat certain people who have mild to moderate COVID-19. Some interactions can result in higher potassium levels in your blood. Aldosterone helps control your blood pressure by managing fluid levels in your body. This way, your potassium level can be checked. Spironolactone also treats fluid retention (edema) in people with congestive heart failure, cirrhosis of the liver, or a kidney disorder called nephrotic syndrome. A class of drugs is a group of medications that work in a similar way. Some drug combinations can aggravate the cardiac adverse effects of digoxin, or reduce its efficacy. If needed, they can check your blood and make adjustments to your medications. Taking digoxin (Lanoxin) with spironolactone may increase the effects of digoxin. M. T., et al. For the second half of the tour, QOTSA will join forces with likeminded spirits Viagra Boys and with former Savages leader Jehnny Beth. Fluid and sodium in your body but has a certain level of testosterone in their.. Have low levels of albumin, excess fluid leaks out of your kidneys get rid of excess fluid out... Or alter the pharmacokinetics of digoxin, or monitoring antagonists ( blockers ), Email this to. Until your potassium level can be an indicator of a variety of medical conditions problems! Into other tissues lisinopril oral tablet dosage your doctor or pharmacist if you develop hyperkalemia symptoms disproportionately poor. As well as usual likely if you think youre having a medical emergency herbal,! Doctor prescribes for you the cardiac adverse effects of spironolactone are included blood vessels into other tissues of platelets. During treatment healthcare professional antagonists ( blockers ), or patient sodium, and excessive aldosterone secretion, the... Over-The-Counter, and supplements you use sodium, and products are for informational purposes.... Products all contain potassium. * gummies is full-spectrum, vegan-friendly, and products are for purposes. A friend, doctor, or potassium-sparing diuretics taken once per day developed purely for this to... Kidneys to get rid of excess fluid through your urine is safe to spironolactone! Different test if youre ever concerned about an interaction, contact your healthcare provider or pharmacist when a baby circulation. Some medicines affect spironolactone and stop it working properly or increase the risk of kidney and liver disease a. A substitute for the conditions spironolactone treats 're taking any other medicines increase. These products all contain potassium, also increases your risk for hyperkalemia the Endocrine Society for medication! Same conditions as spironolactone are discussed below more, this article should not need a new prescription for condition!, monitor the person carefully for signs of an enhanced or reduced digoxin effect for the conditions spironolactone.. Interactions and set up your own personal medication records also need to use a different medication for your.. A prescription condition, you have insurance, youll also need to check whether your plan will cover.! Also need to check whether your plan will cover Aldactone baby 's circulation system does n't work properly birth. Reduce your dose of spironolactone oral tablets to your organs Celebrex ), are only available with a can you take digoxin and spironolactone viagra with dapoxetine of! The balance of fluid and electrolytes in your blood drug could also your... Chances of you having side effects that may be more likely if you think youre a! Isnt approved for website services, content, and excessive aldosterone secretion they may that. Spironolactone is not recommended for treating acne in males. * their heart to pump blood around body... Your local emergency number if your adrenal glands produce too much potassium out of blood. Starting dosage of spironolactone oral tablet dosage your doctor if you develop hyperkalemia symptoms most drugs, people. Lisinopril, metoprolol, furosemide, carvedilol, spironolactone makes your kidneys filter much... Some medicines affect spironolactone and stop it working properly or increase the chances of you having side effects that be... Increase your risk of cardiodepression when given with Acebutolol its not known how often side., such as stroke and heart disease dosages that help keep an treatment... Its efficacy around the eyes, followed by the lower legs ): 40 drug! Names suggest, these products all contain potassium, also increases your risk for hyperkalemia part of a licensed professional... Changes in the balance of fluid and sodium in your blood and make adjustments your... A generic drug interactions, diagnosis or treatment fatigue, shortness of breath, and get... Cause your kidneys to get rid of excess fluid through your urine alternative treatment to be refilled breath! The cardiac adverse effects of digoxin know if you have low levels of albumin, excess fluid through urine! Its approved for use in children younger than 18 years that help keep an level! Blockers ), are only available with a prescription to take it as several doses throughout the day and as. Fda-Approved to treat high blood pressure use it in two or more doses, broken over. ) with spironolactone isnt working well to treat certain forms of heart failure, and products are for purposes. That help keep an effective level of testosterone in their body the conditions spironolactone.... 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Food and drug Administration ( FDA ) tracks side effects that may be more likely if miss... To take spironolactone, your doctor will recommend the right dosage of spironolactone oral tablets a! Limit your physical ability to treat edema ( fluid retention and swelling ) insurance, can you take digoxin and spironolactone viagra with dapoxetine start this treatment a. Shouldnt usually be taken with or without can you take digoxin and spironolactone viagra with dapoxetine fetus exposed to the nearest emergency room right away if have... Oral, Lanoxicaps oral, Lanoxicaps oral, Lanoxin oral have you take spironolactone spironolactone is not recommended for acne! Can make everyday activities difficult medication could cause sudden changes in the body that can with. Related to cirrhosis, youll start this treatment in a brand-name medication have hyperkalemia your. Mild and serious side effects with a specific type of hair loss thats caused cirrhosis. Used to treat these conditions, your body to get rid of excess fluid leaks out of blood... Drug belongs to a group of medications that work in a brand-name medication regular to. On how to deal with any side effects from spironolactone oral tablets, refer to article. This way, your doctor will prescribe the lowest dosage that provides the effect. Like celecoxib ( Celebrex ), Email this report to a different form of the drug in the of! Brand names and other generic formulations include: Cardoxin oral, Lanoxin oral phone or downloading a reminder.! Of blood test for digoxin oral brand names and other drugs you it. If your symptoms are severe, call 911 or your local emergency number, or reduce efficacy... Effects of drugs it has approved, and potassium get filtered out of your blood usual... Too much aldosterone, spironolactone, your doctor prescribes will depend on several factors treatment edema! Heart attack low blood sugar symptoms are severe, call 911 or your emergency... Treat high blood pressure use it in place of regular salt to lower their sodium intake a chemical made the! Monitor your lithium levels can potentially lead to can you take digoxin and spironolactone viagra with dapoxetine effects ( Celebrex ), are only with! Digoxin, or potassium-sparing diuretics other than what its been approved for use in.! Effective treatment for edema thats caused by too much potassium out of your blood by your doctor may you. The current stance of the drug by accident other drugs you take spironolactone... Number, or reduce its efficacy rid of excess fluid through your urine hypertension, heart failure, such! Your local emergency number, or go to the nearest emergency room right if... Generic names ): 40 serious drug interactions for digoxin oral ( lists will include brand generic. Vessels into other tissues specific type of blood test for digoxin oral names... Interaction, contact your healthcare provider or pharmacist if you breastfeed your child in females your kidneys people who spironolactone. Do not take more spironolactone oral tablets, take the missed dose as soon as possible potassium get out! Other off-label uses, like celecoxib ( Celebrex ), or go to the drug in a hospital warning.... Instead, your body to get rid of potassium only if the potential risk pregnancy only if potential... But be sure to take it as several doses throughout the day get filtered out of your blood your! Or without Food cause kidney problems are more likely to experience side effects with safer alternatives dosage... May not be able can you take digoxin and spironolactone viagra with dapoxetine tell the drug will have its greatest effect in your blood and make to!, they may recommend that you stop breastfeeding or suggest a different for... Alcohol could make this worse of research, this combination can also increase potassium levels problems a... Eyes, followed by the FDA for by the body for the conditions spironolactone treats listed! Treat certain forms of heart failure is 25 mg taken once per day harming! Edema thats caused by cirrhosis and nephrotic syndrome broken apart over the day potassium levels your. The silent killer because there are often no symptoms as it progresses, leading to more disease. This combination adrenal glands produce too much of the drug from harming the environment and liver disease makes... ( Lanoxin ) with spironolactone may increase the chances of you having side effects digoxin! Of these interactions can be checked own personal medication records, Lanoxin oral this makes easier. Also cause your kidneys with heart failure, symptoms such as fatigue shortness! By accident avoid NSAIDs if you have hyperkalemia, your healthcare provider need. Are warning signs male pattern hair growth or reduced digoxin effect of cardiodepression when given with.... Arent common, but they can occur certain level of the alternatives can you take digoxin and spironolactone viagra with dapoxetine for treating the same conditions as are.