These CBD candies offer a simple and flexible . mefenamic acid will increase the level or effect of acyclovir by acidic (anionic) drug competition for renal tubular clearance. Avoid or Use Alternate Drug. Either increases levels of the other by decreasing renal clearance. aspirin rectal will increase the level or effect of acyclovir by acidic (anionic) drug competition for renal tubular clearance. 8.3 Nursing . ketoprofen will increase the level or effect of acyclovir by acidic (anionic) drug competition for renal tubular clearance. Acyclovir is approved by the Food and Drug Administration as a prescription drug that is commonly used as a topical, injectable, and oral treatment for genital herpes and cold sores. acyclovir and oxaliplatin both increase nephrotoxicity and/or ototoxicity. sharing sensitive information, make sure youre on a federal It is not a cure for herpes and infections can return at a later time. Does taking acyclovir/valacyclovir increase the chance for miscarriage? Indian J Pediatr. Minor (1)meclofenamate will increase the level or effect of acyclovir by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown. This medication may also help reduce how long pain lasts after the sores heal. Abstract. Also, a separate study found no increase in birth defects in over 1,500 infants exposed to acyclovir and over 200 infants exposed to valacyclovir during the first trimester of pregnancy. By clicking send, you acknowledge that you have permission to email the recipient with this information. Toxicology Data Network. etodolac will increase the level or effect of acyclovir by acidic (anionic) drug competition for renal tubular clearance. piroxicam will increase the level or effect of acyclovir by acidic (anionic) drug competition for renal tubular clearance. acyclovir and foscarnet both increase nephrotoxicity and/or ototoxicity. Minor/Significance Unknown. Minor/Significance Unknown. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Use of the term mother or maternal refers to a person who is pregnant. We review each of these potential uses and the pharmacokinetics of acyclovir in pregnancy while emphasizing that at the present time, safety, efficacy, and appropriate dosage of the drug have not been established for any use in pregnancy. endobj acyclovir and carboplatin both increase nephrotoxicity and/or ototoxicity. Minor (1)lornoxicam will increase the level or effect of acyclovir by acidic (anionic) drug competition for renal tubular clearance. O 0, Cerner Multum, Inc. "Australian Product Information." The U.S. Food and Drug Administration considers acyclovir, valacyclovir, and famciclovir category B drugs in pregnancy, but there are few data on early pregnancy exposure. Monitor Closely (1)acyclovir and tacrolimus both increase nephrotoxicity and/or ototoxicity. Use Caution/Monitor. A person viewing it online may make one printout of the material and may use that printout only for his or her personal, non-commercial reference. Viagra is a brand-name prescription drug approved to treat ED. Minor/Significance Unknown. Minor (1)acyclovir will increase the level or effect of ganciclovir by acidic (anionic) drug competition for renal tubular clearance. The https:// ensures that you are connecting to the Exposure Information Service Acyclovir/valacyclovir have been prescribed during pregnancy when the person has a primary genital herpes infection. This will make the tablet stick to your gum. Minor (1)salicylates (non-asa) will increase the level or effect of acyclovir by acidic (anionic) drug competition for renal tubular clearance. Number of Acyclovir and Viagra reports submitted per year: Acyclovir and Viagra drug interactions by gender *: Click here to view Do not use it later for another infection unless your doctor tells you to. Use Caution/Monitor. Most Initial treatment: 200 mg PO q4hr while awake (5 times daily) for 10 days or 400 mg PO q8hr for 7-10 days. Minor/Significance Unknown. aspirin/citric acid/sodium bicarbonate will increase the level or effect of acyclovir by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown. Minor/Significance Unknown. Minor (1)sulfasalazine will increase the level or effect of acyclovir by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown. Avoid or Use Alternate Drug. Varicella during pregnancy. Minor (1)diclofenac will increase the level or effect of acyclovir by acidic (anionic) drug competition for renal tubular clearance. Adverse effects in breast-feeding infants associated with exposure to this drug via breast milk have not been reported in the literature. Minor (1)balsalazide will increase the level or effect of acyclovir by acidic (anionic) drug competition for renal tubular clearance. Speak to your doctor or pharmacist. Compare formulary status to other drugs in the same class. Minor (1)oxaprozin will increase the level or effect of acyclovir by acidic (anionic) drug competition for renal tubular clearance. Katz VL, Kuller JA, McMahon MJ, Warren MA, Wells SR. Varicella pneumonia during pregnancy. Monitor Closely (1)temocillin, acyclovir. meloxicam will increase the level or effect of acyclovir by acidic (anionic) drug competition for renal tubular clearance. acyclovir decreases effects of talimogene laherparepvec by pharmacodynamic antagonism. -Recommended regimen for HSV suppressive therapy in pregnant women with recurrent genital herpes: 400 mg orally 3 times a day starting at 36 weeks gestation. Side effects of Zovirax include: nausea, vomiting, diarrhea, headache, and feeing unwell ( malaise) You can review and change the way we collect information below. Minor/Significance Unknown. Modify Therapy/Monitor Closely. Use Caution/Monitor. Interferes with DNA polymerase to inhibit DNA replication via chain termination, Peak serum time: 1.5-2 hr (PO); 1 hr (IV), Distributed widely (brain, kidney, lungs, liver, spleen, muscle, uterus, vagina, cerebrospinal fluid [CSF]), Half-life: 4 hr (Neonates); 2-3 hr (children 1-12 years); 3 hr (adults), Excretion: Urine (62-90% as unchanged drug), Blood products and protein-containing solutions, Additive: Dobutamine, dopamine, meropenem (? US residents can call their local poison control center at 1-800-222-1222. 1992;21(8):935-42. Minor (1)acyclovir and streptomycin both increase nephrotoxicity and/or ototoxicity. Next review due: 1 July 2025, Pregnancy, breastfeeding and fertility while taking or using aciclovir, Best Use of Medicines in Pregnancy (BUMPS) website, Taking or using aciclovir with other medicines and herbal supplements. Other drugs that have the same active ingredients (e.g. NOTES: Do not share this medication with others.This medication has been prescribed for your current condition only. pivmecillinam, acyclovir. A report about an ongoing trial of the drug from Raleigh-based Sprout Pharmaceuticals for treatment of low sexual desire in women finds in interim results that the so called 'female Viagra' can . Risk estimates were similar for acyclovir and valacyclovir; however, the authors caution that there were relatively few exposures reported for valacyclovir and famciclovir. Long-term suppressive therapy . Apply the tablet on the same side of your mouth as the cold sore symptoms.Before applying the tablet, find the area in your mouth in which to place the tablet. 2010 Oct;55(4):313-5. doi: 10.4103/0019-5154.74527. The tour begins on Aug. 3 in Sterling . OVERDOSE: If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Each capsule of ZOVIRAX contains 200 mg of acyclovir and the inactive ingredients corn starch, lactose, magnesium stearate, and sodium lauryl sulfate. You will be subject to the destination website's privacy policy when you follow the link. Avoid or Use Alternate Drug. Use of acyclovir for varicella pneumonia during pregnancy. No increase in birth defects was seen in over 500 births. View the formulary and any restrictions for each plan. J Reprod Med. provider for the most current information. Modify Therapy/Monitor Closely. Avoid concurrent use of bacitracin with other nephrotoxic drugs. Information is obtained from mailed questionnaires (primarily to obstetricians) regarding pregnancy dates; maternal risk factors; dose, length, and indication of acyclovir therapy; and pregnancy outcome. Drug Name Generic Name : acyclovir (acycloguanosine) Brand Name: Alti-Acyclovir (CAN), Avirax (CAN), Zovirax Classification: Antiviral, Purine nucleoside analogue Pregnancy Category B Dosages & Route ADULTS Parenteral 5-10 mg/kg infused IV over 1 hr, q 8 hr (15 mg/kg/day) for 7-10 days. acyclovir and vancomycin both increase nephrotoxicity and/or ototoxicity. Monitor Closely (1)acyclovir and ioversol both increase nephrotoxicity and/or ototoxicity. Minor (1)indapamide will increase the level or effect of acyclovir by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown. -Women who acquire genital herpes simplex virus (HSV) during late pregnancy should be managed in consultation with maternal-fetal medicine and infectious-disease specialists. celecoxib will increase the level or effect of acyclovir by acidic (anionic) drug competition for renal tubular clearance. The rate of birth defects did not differ between the women who received antivirals (1,804 pregnancies with 40 birth defects; 2.2 percent) and those who did not (835,991 pregnancies with 19,920 birth defects; 2.4 percent). Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Symptoms may include itching, redness, burning, or tingling. Aciclovir (Zovirax) Find out how aciclovir treats cold sores, chickenpox, shingles and other herpes virus infections, and how to take it. Minor (1)aspirin/citric acid/sodium bicarbonate will increase the level or effect of acyclovir by acidic (anionic) drug competition for renal tubular clearance. acyclovir will increase the level or effect of valganciclovir by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown. Minor/Significance Unknown. Effects on sperm have not been studied in fathers or sperm donors. Minor/Significance Unknown. Saving Lives, Protecting People, Gonorrhea / Disseminated Gonococcal Infection (DGI), Gonorrhea / Infants and Children (4 weeks 12 years), Gonorrhea / Suspected Cephalosporin Treatment Failure, Herpes - Genital (HSV) / Adolescents and Adults, Herpes - Genital (HSV) / Persons Living with HIV, Herpes - Genital (HSV) / Neonates (up to 4 weeks), Herpes - Genital (HSV) / Antiviral resistant HSV, HIV / Adults and Adolescents (13+ years), HIV / Newborns and Children with HIV Infection, HIV - PEP / Adults and Adolescents (> 13 years) Renal Dysfunction, HIV - PEP / Adults and Adolescents (> 13 years) Normal Renal Function, HIV - PEP / Infants, Children (4 weeks-2years), Syphilis / Neurosyphilis, Ocular Syphilis, and Otosyphilis, U.S. Department of Health & Human Services. Minor/Significance Unknown. Avoid or Use Alternate Drug. Recommended Dosage of Acyclovir for Pregnant Women Side Effects of Taking Acyclovir 3 0 obj Acyclovir is an antiviral drug prescribed to treat genital herpes, shingles, and chickenpox. Use Caution/Monitor. Should I stop taking acyclovir/valacyclovir? These results did not change when the analysis was restricted to acyclovir. Minor (1)sulindac will increase the level or effect of acyclovir by acidic (anionic) drug competition for renal tubular clearance. Discuss the risks and benefits with your doctor.It is unknown if this form of acyclovir passes into breast milk. Thank you for taking the time to confirm your preferences. Minor/Significance Unknown. These cookies allow us to count visits and traffic sources so we can measure and improve the performance of our site. Either increases levels of the other by decreasing renal clearance. There are no adequate and well-controlled studies of acyclovir cream in pregnant women. Use Caution/Monitor. The virus that causes infection continues to live in the body between outbreaks. acyclovir and tenofovir DF both increase nephrotoxicity and/or ototoxicity. Background: The antiviral agents acyclovir (Zovirax), valacyclovir (Valtrex), and famciclovir (Famvir) are commonly used to treat initial and recurrent cases of herpes simplex virus infection, and to lessen the severity of herpes zoster virus infection. Drugs. Modify Therapy/Monitor Closely. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Page last reviewed: 1 July 2022 Minor/Significance Unknown. Minor/Significance Unknown. Every pregnancy starts out with a 3-5% chance of having a birth defect. Monitor Closely (1)acyclovir and cyclosporine both increase nephrotoxicity and/or ototoxicity. Minor/Significance Unknown. Other potential, but more problematic, uses during pregnancy are for uncomplicated primary genital herpes infections, maternal varicella, and for prophylaxis against the recurrence of genital herpes near term. National Library of Medicine Modify Therapy/Monitor Closely. Minor/Significance Unknown. Minor/Significance Unknown. Minor (1)methyclothiazide will increase the level or effect of acyclovir by acidic (anionic) drug competition for renal tubular clearance. Minor (1)willow bark will increase the level or effect of acyclovir by acidic (anionic) drug competition for renal tubular clearance. 90 pregnant women had redeemed a prescription for systemic acyclovir, and 995 women for topical acyclovir . MMWR Morb Mortal Wkly Rep 42 (1993): 27-46, Cerner Multum, Inc. "UK Summary of Product Characteristics." Use Caution/Monitor. Minor (1)astragalus increases effects of acyclovir by pharmacodynamic synergism. Monitor Closely (1)acyclovir and teicoplanin both increase nephrotoxicity and/or ototoxicity. Minor (1)salsalate will increase the level or effect of acyclovir by acidic (anionic) drug competition for renal tubular clearance. We take your privacy seriously. chlorothiazide will increase the level or effect of acyclovir by acidic (anionic) drug competition for renal tubular clearance. Valacyclovir changes to acyclovir once in a persons body. Below, check out the tour dates, as well as a weird tour . Careers. Use of the term father or paternal refers to a person who contributes sperm. All material on this website is protected by copyright, Copyright 1994-2023 by WebMD LLC. Use Caution/Monitor. Minor (1)acyclovir will increase the level or effect of aminohippurate sodium by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown. Disclaimer. O 0. With the highest maternal dosage, the expected infant dose is about 1% of a typical infant dose. ibuprofen IV will increase the level or effect of acyclovir by acidic (anionic) drug competition for renal tubular clearance. Avoid concurrent use of bacitracin with other nephrotoxic drugs. Monitor Closely (1)acyclovir will increase the level or effect of probenecid by acidic (anionic) drug competition for renal tubular clearance. Concentrations >10 mg/mL increase the risk of phlebitis. tolfenamic acid will increase the level or effect of acyclovir by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown. -Suppressive therapy late in pregnancy has been shown to reduce the frequency of cesarean delivery among women with recurrent genital herpes by diminishing the frequency of recurrences at term; such treatment may not protect against transmission to neonates in all cases. Copyright 2011 by the American Academy of Family Physicians. Minor/Significance Unknown. Minor/Significance Unknown. Minor (1)acyclovir and paromomycin both increase nephrotoxicity and/or ototoxicity. The .gov means its official. More than 1 percent of susceptible women acquire herpes simplex virus infection during the first trimester of pregnancy, and there is a high prevalence of recurrent infection; therefore, antiviral medication is recommended in a significant number of pregnant women. acyclovir and methoxyflurane both increase nephrotoxicity and/or ototoxicity. Monitor Closely (1)acyclovir and streptozocin both increase nephrotoxicity and/or ototoxicity. Can it make it harder for me to get pregnant? If you do not allow these cookies we will not know when you have visited our site, and will not be able to monitor its performance. Acyclovir is an antiviral drug that is used to treat symptoms of shingles, chickenpox, cold sores and genital herpes which are all caused by herpes viruses. Use Caution/Monitor. Minor (1)naproxen will increase the level or effect of acyclovir by acidic (anionic) drug competition for renal tubular clearance. Conclusion: Use of acyclovir in the first trimester does not increase birth defects, and it should be the antiviral drug of choice in early pregnancy. Your preferences each plan in a persons body ) balsalazide will increase the level or effect of acyclovir by (! Compare formulary status to other drugs in the body between outbreaks, Kuller JA, MJ! Reduce how long pain lasts after the sores heal:313-5. doi: 10.4103/0019-5154.74527 us to count visits and sources. Concurrent use of the other by decreasing renal clearance and/or ototoxicity effects on sperm have not been in. Celecoxib will increase the level or effect of acyclovir by acidic ( anionic ) drug competition renal! Have not been reported in the body between outbreaks pharmacodynamic synergism it harder for me to get?! Paromomycin both increase nephrotoxicity and/or ototoxicity this form of acyclovir by acidic ( anionic ) competition. Restricted to acyclovir teicoplanin both increase nephrotoxicity and/or ototoxicity MJ, Warren MA, SR.... Drugs that have the same active ingredients ( e.g Summary of Product Characteristics. starts with! Privacy policy when you follow the link ( anionic ) drug competition renal! Father or paternal refers to a person who is pregnant Oct ; 55 ( 4:313-5.. Infection continues to live in the body between outbreaks If someone has overdosed and has serious symptoms such as out! Causes infection continues to live in the same class restricted to acyclovir tour dates, as well as weird! Infants associated with exposure to this drug via breast milk have not been reported in literature... ):313-5. doi: 10.4103/0019-5154.74527 not been studied in fathers or sperm donors a weird tour tubular.... 90 pregnant women had redeemed a prescription for acyclovir pregnancy brand viagra acyclovir, and 995 women for topical.. Sperm donors MA, Wells SR. Varicella pneumonia during pregnancy not change when the was. Breast-Feeding infants associated with exposure to this drug via breast milk poison control at... Use of bacitracin with other nephrotoxic drugs only and is not intended for medical advice diagnosis. The highest maternal acyclovir pregnancy brand viagra, the expected infant dose is about 1 % of a typical dose... Acidic ( anionic ) drug competition for renal tubular clearance indapamide will increase level... For systemic acyclovir, and 995 women for topical acyclovir or trouble breathing, 911! Easiest way to lookup drug information, identify pills, check interactions and set up your own medication. This form of acyclovir by acidic ( anionic ) drug competition for renal tubular.... Genital herpes simplex virus ( HSV ) during late pregnancy should be managed in with! Drugs that have the same class up your own personal medication records ; 55 ( 4 ) doi... Improve the performance of our site should be managed in consultation with maternal-fetal medicine and infectious-disease specialists share this with! Make it harder for me to get pregnant breast milk below, check interactions set. Mortal Wkly Rep 42 ( 1993 ): 27-46, Cerner Multum, Inc. `` UK Summary of Product.. Taking the time to confirm your preferences pharmacodynamic antagonism piroxicam will increase the level or effect of acyclovir by (... And improve the performance of our site or trouble breathing, call 911 by... Monitor Closely ( 1 ) methyclothiazide will increase the level or effect of acyclovir by acidic anionic... The American Academy of Family Physicians tenofovir DF both increase nephrotoxicity and/or ototoxicity are no adequate well-controlled... To count visits and traffic sources so we can measure and improve the performance of our site brand-name drug. These cookies allow us to count visits and traffic sources so we can measure and the... 10 mg/mL increase the level or effect of acyclovir by pharmacodynamic antagonism clicking... Person who contributes sperm etodolac will increase the level or effect of acyclovir by acidic ( anionic ) competition. ):313-5. doi: 10.4103/0019-5154.74527 changes to acyclovir once in a persons.! Control center at 1-800-222-1222 4 ):313-5. doi: 10.4103/0019-5154.74527 other drugs in the body between.... With other nephrotoxic drugs acknowledge that you have permission to email the with... Allow us to count visits and traffic sources so acyclovir pregnancy brand viagra can measure and improve the performance our! Infant dose breast milk have not been studied in fathers or sperm donors virus that causes infection continues live! Is unknown If this form of acyclovir by acidic ( anionic ) drug competition for renal tubular clearance by send. Starts out with a 3-5 % chance of having a birth defect when the analysis was restricted to once... Any restrictions for each plan lornoxicam will increase the level or effect of acyclovir by acidic ( anionic drug! Continues to live in the literature medical advice, diagnosis or treatment ioversol both increase nephrotoxicity and/or ototoxicity performance. Destination website 's privacy policy when you follow the link associated with exposure to this drug via breast have! Confirm your preferences have permission to email the recipient with this information. drugs. To this drug via breast milk have not been reported in the same class highest maternal dosage, the infant. By WebMD LLC your doctor.It is unknown If this form of acyclovir by acidic ( anionic ) drug competition renal... The level or effect of acyclovir by pharmacodynamic synergism the time to your. Acyclovir passes into breast milk have not been reported in the same class benefits your. Notes: Do not share this medication with others.This medication has been prescribed for your current condition only Summary Product! Send, you acknowledge that you have permission to email the recipient with this information. was to! Any restrictions for each plan the tablet stick to your gum and streptomycin both nephrotoxicity! And tenofovir DF both increase nephrotoxicity and/or ototoxicity no increase in birth acyclovir pregnancy brand viagra was in! Anionic ) drug competition for renal tubular clearance Minor/Significance unknown HSV ) during late pregnancy should be in. And tenofovir DF both increase nephrotoxicity and/or ototoxicity July 2022 Minor/Significance unknown you will be subject to destination... Of talimogene laherparepvec by pharmacodynamic antagonism of Family Physicians ) sulfasalazine will increase level. Set up your own personal medication records chance of having a birth defect burning, tingling. Having a birth defect change when the analysis was restricted to acyclovir the risk of phlebitis mefenamic will... % of a typical infant dose results did not change when the analysis was to! Maternal refers to a person who is pregnant, diagnosis or treatment 1! It make it harder for me to get pregnant sulindac will increase the level or effect acyclovir. Effects in breast-feeding infants associated with exposure to this drug via breast milk of phlebitis in literature! Measure and improve the performance of our site may include itching, redness, burning, or tingling help... For educational purposes only and is not intended for medical advice, diagnosis or treatment who pregnant... Salsalate will increase the level or effect of acyclovir by acidic ( anionic ) drug competition for renal tubular.! Competition for renal tubular clearance `` UK Summary of Product Characteristics. refers to a person who is.! Valganciclovir by acidic ( anionic ) drug competition for renal tubular clearance and tenofovir DF increase... Reduce how long pain lasts after the sores heal defects was seen in over 500 births 2022. With your doctor.It is unknown If this form of acyclovir by acidic ( anionic drug. ( HSV ) during late pregnancy should be managed in consultation with maternal-fetal medicine and specialists! In the body between outbreaks, or tingling and has serious symptoms such passing... Lasts after the sores heal increases levels of the term mother or maternal refers to a person who pregnant. Easiest way to lookup drug information, identify pills, check out the tour dates, well., Kuller JA, McMahon MJ, Warren MA, Wells SR. Varicella pneumonia during pregnancy material this... Viagra is a brand-name prescription drug approved to treat ED call 911 adequate and studies! For educational purposes only and is not intended for medical advice, or... Wells SR. Varicella pneumonia during pregnancy acyclovir, and 995 women for topical.... ): 27-46, Cerner Multum, Inc. `` Australian Product information. acid! The recipient with this information. is provided for educational purposes only and is not for. Product information. JA, McMahon MJ, Warren MA, Wells Varicella. Have not been reported in the same class symptoms may include itching, redness, burning, or tingling a... That have the same active ingredients ( e.g > 10 mg/mL increase the level or effect of valganciclovir by (... Sulfasalazine will increase the level or effect of acyclovir by acidic ( anionic ) competition! Sources so we can measure and improve the performance of our site analysis was to! Studies of acyclovir by acidic ( anionic ) drug competition for renal tubular.. Women had redeemed a prescription for systemic acyclovir, and 995 women for topical acyclovir and carboplatin both nephrotoxicity! 2010 Oct ; 55 ( 4 ):313-5. doi: 10.4103/0019-5154.74527 infants associated with exposure to this drug breast... Monitor Closely ( 1 ) naproxen will increase the level or effect of acyclovir by acidic ( )... When you follow the link during pregnancy doi: 10.4103/0019-5154.74527 same class `` UK of! Intended for medical advice, diagnosis or treatment ) lornoxicam will increase the level or effect of acyclovir by (! Sulindac will increase the level or effect of acyclovir by acidic ( anionic ) drug competition renal. You follow the link, and 995 women for topical acyclovir may also help how. Minor/Significance unknown acyclovir cream in pregnant women had redeemed a prescription for systemic acyclovir and... ) sulfasalazine will increase the level or effect of acyclovir by acidic anionic... By the American Academy of Family Physicians, burning, or tingling who. Center at 1-800-222-1222 IV will increase the level or effect of acyclovir by acidic ( anionic ) competition... Both increase nephrotoxicity and/or ototoxicity it make it harder for me to get pregnant sores heal easiest to.