Manage and view all your plans together even plans in different states. Consult your doctor or pharmacist for more details. Use Caution/Monitor. erythromycin lactobionate will increase the level or effect of streptomycin by P-glycoprotein (MDR1) efflux transporter. Minor/Significance Unknown. Other (see comment). Minor (1)paromomycin and streptomycin both increase nephrotoxicity and/or ototoxicity. Streptomycin elimination is mainly renal with 50-60% being excreted unchanged; renal function should be assessed regularly in patients receiving streptomycin, and it should be used with caution when renal function is suboptimal. Minor/Significance Unknown. Monitor Closely (1)cidofovir and streptomycin both increase nephrotoxicity and/or ototoxicity. Use Caution/Monitor. Minor/Significance Unknown. streptomycin and teicoplanin both increase nephrotoxicity and/or ototoxicity. Risk of apnea. Minor (1)sulfasalazine increases levels of streptomycin by decreasing renal clearance. carboplatin and streptomycin both increase nephrotoxicity and/or ototoxicity. Minor/Significance Unknown. Applies only to oral forms of hormone. streptomycin decreases levels of calcium carbonate by inhibition of GI absorption. Complete antibiotic regimens 2-4 days before initiating microbiota oral. Avoid concurrent use of bacitracin with other nephrotoxic drugs. Serious - Use Alternative (1)streptomycin decreases effects of microbiota oral by pharmacodynamic antagonism. Modify Therapy/Monitor Closely. Do not start, stop, or change the dosage of any medicines without your doctor's approval.Some products that may interact with this drug include: amphotericin B, high doses of aspirin/NSAIDs such as ibuprofen/naproxen.If your doctor has directed you to take low doses of aspirin to prevent heart attack or stroke (usually 81-162 milligrams a day), you should continue to take the aspirin. Streptococcal endocarditis: 500 mg IM 2 times a day, 60 years and older: Applies only to oral forms of hormone. Interaction mainly occurs in preterm infants. Minor/Significance Unknown. Minor/Significance Unknown. OVERDOSE: If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Use Caution/Monitor. Minor/Significance Unknown. Minor (1)fenoprofen increases levels of streptomycin by decreasing renal clearance. Antibacterial agents may decrease efficacy if coadministered. Use Caution/Monitor. streptomycin will decrease the level or effect of estrogens conjugated synthetic by altering intestinal flora. Minor/Significance Unknown. Minor/Significance Unknown. Use Caution/Monitor. diclofenac increases levels of streptomycin by decreasing renal clearance. Use Caution/Monitor. Modify Therapy/Monitor Closely. lornoxicam increases levels of streptomycin by decreasing renal clearance. Interaction mainly occurs in preterm infants. Monitor Closely (1)streptomycin will decrease the level or effect of estrogens conjugated synthetic by altering intestinal flora. Risk of apnea. Applies only to oral form of both agents. Monitor Closely (1)sodium sulfate/?magnesium sulfate/potassium chloride increases toxicity of streptomycin by Other (see comment). Applies only to oral form of both agents. Use Caution/Monitor. Interaction mainly occurs in preterm infants. streptomycin increases effects of succinylcholine by pharmacodynamic synergism. felodipine will increase the level or effect of streptomycin by P-glycoprotein (MDR1) efflux transporter. Use: Treatment of moderate to severe pneumonia not amenable to therapy with less potentially toxic agents which is caused by susceptible strains of K pneumoniae Minor/Significance Unknown. 25 kg (55 pounds)Bacampicillin tablets are not recommended for use in children weighing up to 25 kg (55 pounds). Use Caution/Monitor. An alternate or additional form of birth control may be advisable during concomitant use. Adjust the streptomycin dose to maintain peak serum concentrations of 20 to 35 mcg/mL and trough concentrations of less than 10 mcg/mL. Data not available Interaction mainly occurs in preterm infants. Minor/Significance Unknown. Minor/Significance Unknown. Use Caution/Monitor. Risk of apnea. Minor/Significance Unknown. Monitor Closely (1)streptomycin will decrease the level or effect of estradiol by altering intestinal flora. Use: Treatment of moderate to severe Brucella caused by susceptible strains Interaction mainly occurs in preterm infants. Minor (1)streptomycin decreases levels of calcium citrate by inhibition of GI absorption. Minor (1)diclofenac increases levels of streptomycin by decreasing renal clearance. Serious - Use Alternative (1)streptomycin, cholera vaccine. Interaction mainly occurs in preterm infants. Closely monitor for increased neuromuscular blockade. Minor/Significance Unknown. pentamidine and streptomycin both increase nephrotoxicity and/or ototoxicity. Children: 15 mg/kg IM every 12 hours May cause neuromuscular blockade and respiratory paralysis, especially when given after anesthesia or muscle relaxants. Avoid or Use Alternate Drug. Advise patients to speak to their healthcare provider if they become pregnant, intend to become pregnant, or are breastfeeding. NAME OF THE MEDICINAL PRODUCT Streptomycin (as sulfate) 1g powder for injection1 2. Applies only to oral form of both agents. tobramycin inhaled and streptomycin both increase nephrotoxicity and/or ototoxicity. Use Caution/Monitor. Information last revised April 2023. acyclovir and streptomycin both increase nephrotoxicity and/or ototoxicity. Adding plans allows you to compare formulary status to other drugs in the same class. Children: 20 to 40 mg/kg IM every 6 to 12 hours Avoid or Use Alternate Drug. Minor/Significance Unknown. Minor/Significance Unknown. colistin and streptomycin both increase nephrotoxicity and/or ototoxicity. Avoid or Use Alternate Drug. Use Caution/Monitor. What Are Side Effects of Streptomycin? nefazodone will increase the level or effect of streptomycin by P-glycoprotein (MDR1) efflux transporter. Minor/Significance Unknown. If you notice other effects not listed above, contact your doctor or pharmacist.In the US -Call your doctor for medical advice about side effects. Keep all medications away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Interaction mainly occurs in preterm infants. The risk is higher if you have kidney disease, if you are receiving high doses of this medication, if you use this drug for a long time, if you are an older adult (older than 60 years), or if you develop a severe loss of body water (become dehydrated). Limitation of use: This drug should only be used to treat/prevent infections proven or strongly suspected to be caused by bacteria. Applies only to oral form of both agents. Minor/Significance Unknown. Minor (1)oxaprozin increases levels of streptomycin by decreasing renal clearance. Applies only to oral form of both agents. Use Caution/Monitor. Minor/Significance Unknown. Closely monitor for increased neuromuscular blockade. Monitor Closely (1)nifedipine will decrease the level or effect of streptomycin by P-glycoprotein (MDR1) efflux transporter. Minor/Significance Unknown. [3] For active tuberculosis it is often given together with isoniazid, rifampicin, and pyrazinamide. Use Caution/Monitor. It acts by interfering with normal protein synthesis. amphotericin B deoxycholate and streptomycin both increase nephrotoxicity and/or ototoxicity. Monitor Closely (1)sirolimus will increase the level or effect of streptomycin by P-glycoprotein (MDR1) efflux transporter. Avoid or Use Alternate Drug. Applies only to oral forms of hormone. Other (see comment). Minor (1)meclizine, streptomycin. Interaction mainly occurs in preterm infants. Compare formulary status to other drugs in the same class. streptomycin will decrease the level or effect of pyridoxine by altering intestinal flora. Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature. streptomycin and tobramycin both increase nephrotoxicity and/or ototoxicity. Minor (1)ketorolac intranasal increases levels of streptomycin by decreasing renal clearance. The dose of the oral suspension is based on body weight and must be determined by your doctor. The neurotoxicity of this drug can result in respiratory paralysis from neuromuscular blockage, especially when the drug is given soon after the use of anesthesia or muscle relaxants. Either increases effects of the other by pharmacodynamic synergism. Minor/Significance Unknown. Increased risk of ototoxicity and nephrotoxicity. Avoid or Use Alternate Drug. Interaction mainly occurs in preterm infants. Comment: Coadministration with medications that cause fluid and electrolyte abnormalities may increase the risk of adverse events of seizure, arrhythmias, and renal impairment. However, the use of SM as a primary therapy has . Interaction mainly occurs in preterm infants. Serious - Use Alternative (1)torsemide, streptomycin. (See INDICATIONS AND USAGE. Interaction mainly occurs in preterm infants. Interaction mainly occurs in preterm infants. . 15 mg/kg IM or IV once a day OR 15 to 25 mg IM or IV 3 times a week Injections should be administered within the body of a relatively large muscle, and the site should be alternated. Coadministration with drugs associated with nephrotoxicity may increase the risk for acute and/or chronic nephrotoxicity. Streptomycin is an aminoglycoside antibiotic, which is usually used in veterinary medicine as the sulfate salt. the same dietary dose of streptomycin (200 ppm) and did not see impacts on worker survival, egg-laying behaviour or drone emergence in a bumblebee species (Bombus terrestris). Minor/Significance Unknown. Minor/Significance Unknown. Minor (1)streptomycin decreases levels of magnesium oxide by increasing renal clearance. Interaction mainly occurs in preterm infants. The recommended streptomycin dose is 15 mg/kg (range 12-18 mg/kg) with a maximum in adults of 1 g daily. streptomycin decreases levels of calcium citrate by inhibition of GI absorption. Interaction mainly occurs in preterm infants. A: Generally acceptable. The risk of severe neurotoxic reactions is sharply increased in patients with impaired renal function or pre-renal azotemia. This drug should be given as part of a three-drug regimen in accordance with standard treatment protocols. Monitor Closely (1)clarithromycin will increase the level or effect of streptomycin by P-glycoprotein (MDR1) efflux transporter. Each enhance the neuromuscular blocking effect of the other; may have negative respiratory effects. choline magnesium trisalicylate increases levels of streptomycin by decreasing renal clearance. Trough serum levels weekly for 4 weeks, fortnightly for 4 weeks, then monthly if stable ADVERSE EFFECTS Interaction mainly occurs in preterm infants. Interaction mainly occurs in preterm infants. Treatment of moderate to severe donovanosis and/or granuloma inguinale not amenable to therapy with less potentially toxic agents which are caused by susceptible strains of C granulomatis, Treatment of moderate to severe chancroid not amenable to therapy with less potentially toxic agents which is caused by susceptible strains of H ducreyi, Concomitantly with another antibiotic for the treatment of moderate to severe urinary tract infections not amenable to therapy with less potentially toxic agents which is caused by susceptible strains of E coli, Proteus species, A aerogenes, K pneumoniae, and E faecalis. Minor/Significance Unknown. streptomycin and streptozocin both increase nephrotoxicity and/or ototoxicity. Powder or porous mass of white, odorless, bitter taste. 8 years and older: 1 gram IM once a day PLUS tetracycline or doxycycline. Caution when peramivir coadministered with nephrotoxic drugs. streptomycin increases effects of incobotulinumtoxinA by pharmacodynamic synergism. 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