Erectile dysfunction (ED) is often a symptom . If you have arthritis and your doctor prescribes alendronic acid, let them know if the pain or swelling in your joints gets worse when you start taking this medicine. Adherence to calcium and/or vitamin D supplements of patients treated with alendronic or risedronic acid. What we learned, loved, and are leaving with from, primary amino compound, 1,1-bis(phosphonic acid) (, Osteoporosis caused by Glucocorticoid Treatment, Tyrosine-protein phosphatase non-receptor type 4, Receptor-type tyrosine-protein phosphatase S, Receptor-type tyrosine-protein phosphatase epsilon, M05BB03 Alendronic acid and colecalciferol, M05B DRUGS AFFECTING BONE STRUCTURE AND MINERALIZATION, M05 DRUGS FOR TREATMENT OF BONE DISEASES, M05BB06 Alendronic acid and alfacalcidol, sequential, M05BB05 Alendronic acid, calcium and colecalciferol, sequential, Drugs Affecting Bone Structure and Mineralization, MS/MS Spectrum - Quattro_QQQ 10V, Positive, splash10-014i-2930000000-99692afb4ed253251947, MS/MS Spectrum - Quattro_QQQ 25V, Positive, splash10-001i-0900000000-d2c07307d66e1c7d52e8, MS/MS Spectrum - Quattro_QQQ 40V, Positive, splash10-0kdl-9500000000-c82a6e6e898154627c7d, Predicted MS/MS Spectrum - 10V, Positive (Annotated), Predicted MS/MS Spectrum - 20V, Positive (Annotated), Predicted MS/MS Spectrum - 40V, Positive (Annotated), Predicted MS/MS Spectrum - 10V, Negative (Annotated), Predicted MS/MS Spectrum - 20V, Negative (Annotated), Predicted MS/MS Spectrum - 40V, Negative (Annotated). Do not stop using any medications without first talking to your doctor. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. All generic drug interactions for alendronate oral (lists will include brand and generic names): 21 significant drug interactions. We found that patients aged >50 years and women were likely to be more adherent (P<0.001), and the more the age raises, the more adherent patients are. Assessment and potential determinants of compliance and persistence to antiosteoporosis therapy in Italy. However, if you're trying to get pregnant, speak to a pharmacist or your doctor before taking alendronic acid. This report displays the potential drug interactions for the following 2 drugs: Applies to: Aspirin Low Strength (aspirin) and alendronate. Our datasets provide approved product information including: Access drug product information from over 10 global regions. However, you can significantly reduce the chance of this happening by taking alendronic acid. Broken bones are painful and can have serious consequences. * Approximation only. Then, as patients with osteoporosis using AODs should receive supplemental calcium and vitamin D if dietary intake is inadequate, we assessed the adherence to these supplements (Table 4). Only 51% of patients taking plain bisphosphonates were adherent to the recommended dose of vitamin D in the first year of follow-up, decreasing to 23% in the third year. The main rule with alendronic acid is that you do not take any other medicines by mouth at the same time as your alendronic acid dose, or for at least 30 minutes after taking it. . Federal government websites often end in .gov or .mil. An official website of the United States government. What is Amlodipine? To make sure it's safe for you, tell your doctor if you: Follow your doctor's instructions about how and when to take your medicine. There are 2 alcohol/food interactions with alendronate. Also tell your doctor if you are having chemotherapy. During the accrual period (20072009), from the initial cohort, we selected a subsample of nave patients who had not had an AODs prescription during the 12 months before the index date (first prescription of AODs), but had been treated with AODs (AIFA recommendation number 79) as monotherapy during the 3-year follow-up. Take before a meal. InChI=1S/C4H13NO7P2/c5-3-1-2-4(6,13(7,8)9)14(10,11)12/h6H,1-3,5H2,(H2,7,8,9)(H2,10,11,12), (4-amino-1-hydroxy-1-phosphonobutyl)phosphonic acid, Use our structured and evidence-based datasets to. official website and that any information you provide is encrypted Brand Names Adrovance, Binosto, Fosamax, Fosamax Plus D, Fosavance Generic Name Alendronic acid DrugBank Accession Number DB00630 Background They were able to accurately describe demographic characteristics and treatment profiles in variously treated and differently adherent patients. The https:// ensures that you are connecting to the Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. It is created by eHealthMe based on reports of 1,088 people who take Amlodipine and Alendronic acid from the FDA, and is updated regularly. Russell RG, Watts NB, Ebetino FH, Rogers MJ: Mechanisms of action of bisphosphonates: similarities and differences and their potential influence on clinical efficacy. IOF Invest in your bones. Common interactions include diarrhoea among females and dyspnoea among males. Pharmaceutical data consist of the dispensed drug name, ATC (Anatomical Therapeutic Chemical classification group), dose, number of packages, and dispensing date.12 Demographic information about patients was made anonymous, according to Italian law regarding the protection of privacy. [Accessed February 1, 2016]; Varenna M, Binelli L, Casari S, Zucchi F, Sinigaglia L. Effects of dietary calcium intake on body weight and prevalence of osteoporosis in early postmenopausal women. However, both were likely to lose their potential association with high adherence from the 12th month of follow-up. Drug created at June 13, 2005 13:24 / Updated at June 08, 2023 10:20, Structured drug data for data science & ML, Clinical intelligence tool for your software, Search for drug interactions with our API, Get drug allergy and cross sensitivities info. Alendronic acid is a second generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's diseaseLabel1,5. The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Alendronic acid is combined with Acipimox. Page last reviewed: 10 September 2021 This information should not be interpreted without the help of a healthcare provider. Abbreviations: CI, confidence interval; OR, odds ratio. This affects not only public health, but also socioeconomic factors.47 Between 2000 and 2008, elderly Italian citizens experienced more than half a million hip fractures, which have cost about 8.5 billion.2 The underlying causes of low adherence are multifactorial and relate to patient, physician, and therapeutic choice.9 Some of them have been widely defined in literature, but further studies are needed to get through to prevent consequences.57,9,10 The aim of this retrospective observational study was to assess the adherence to first-line antiosteoporosis therapy (alendronate or risedronate, with or without calcium and vitamin D supplements) in an Italian setting. Adami S, De Rosa M, Martini N, Pedrini A, Rossini M, Scroccaro G. Osservatorio ARNO Patologie Osteoarticolari Focus su Osteoporosi e Artrite Reumatoide [Osteoarticular disorders in ARNO Observatory], AgenziaFarmaco.gov.it [homepage on the Internet], Rapporto Osmed 2013 [National Report of Medicines use in Italy. There are 7 disease interactions with alendronate which include: Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. You can drink tap water but this medicine must be taken on an empty stomach. Patients may experience hypocalcemia, hypophosphatemia, and upper gastrointestinal events.Label. [, Guo RT, Cao R, Liang PH, Ko TP, Chang TH, Hudock MP, Jeng WY, Chen CK, Zhang Y, Song Y, Kuo CJ, Yin F, Oldfield E, Wang AH: Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases. Netdoctor participates in various affiliate marketing programs, which means we may get paid commissions on editorially chosen products purchased through our links to retailer sites. We comply with the HONcode standard for trustworthy health information. Your doctor may also recommend a dental check-up before your treatment starts, contact your doctor or dentist if you have any problems with your mouth or teeth, such as pain, swelling or loose teeth. Correspondence: S Calabria, Health Care Systems Department, CINECA, Via Magnanelli 6/3, 40033 Casalecchio di Reno, Bologna, Italy, Tel +39 051 716 1348, Fax +39 051 613 2198, Email, The full terms of this license are available at. Use of this site constitutes acceptance of eHealthMe.com's terms of service and privacy policy. DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. No alendronic acid is recovered in the fecesLabel2,3. Alendronic acid is generally prescribed for a long time. Visit Yellow Card for further information. Patients in the study may take other drugs besides Amlodipine and Alendronic acid. Alendronic acid does not affect any type of contraception including the contraceptive pill or emergency contraception. Chiu C, Kuo M, Yu S, Su BY, Cheng T. Adherence to osteoporosis regimens among men and analysis of risk factors of poor compliance: a 2-year analytical review. Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. Epub 2019 Feb 28. However, drinking a lot of alcohol affects the strength of your bones and can increase your risk of breaks (fractures). In case of combination therapy, at least 600 unit doses should be prescribed to patients. The best time to take your medicine is usually 30 minutes before you have breakfast. GOV.UK has moreinformation on the law on drugs and driving. Casula M, Catapano AL, Piccinelli R, et al. Evidence from the AIFA-BEST observational study. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Forms available from special-order manufacturers include: oral solution. Bone resorption causes local acidification, releasing risedronic acid which is that taken into osteoclasts by fluid-phase endocytosis 1. Like all medicines, alendronic acid can cause side effects in some people, but many people have no side effects, or only minor ones. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Abbreviation: AODs, antiosteoporosis drugs. Of the total drug interactions, 2 are major, 103 are moderate, and 5 are minor. The use of drugs for peptic ulcer and gastroesophageal reflux disease and of corticosteroids for systemic use were significantly associated with high adherence at different times. It constantly decreased during the 3-year follow-up period for all AODs. Alendronic acid has been studied for use in pediatric patientsLabel. Percentages of adherent patients are calculated as the number (N) of patients adherent to the drug on the total of patients who received the respective drug prescription (15,521 received alendronic acid, 10,485 FDC and 13,997 risedronic acid). It should be taken as soon as you get out of bed in the morning and at least 30 minutes before any food, beverage, or other medicines. This is because we only expect very small amounts to pass into breast milk. DRUG INTERACTIONS. While you're taking it, you're less likely to break a bone. Usually avoid combinations; use it only under special circumstances. Do not have anything to eat or drink beforehand, other than plain tap water. It's important to follow the instructions carefully (the how and when to take this medicine section has more detail), so that your medicine works properly. If you need to take both your doctor may want to monitor your calcium levels more closely. generic drugs) are not considered. use caution when coadministering with other drugs known to increase the risk of peptic ulcers or gastric hemorrhage including alendronate. Dosage of drugs is not considered in the study. The risk or severity of nephrotoxicity and hypocalcemia can be increased when Adefovir dipivoxil is combined with Alendronic acid. Starting from this population, a cohort of 3.3 million patients aged 40 years and more (57% of the overall population) was selected.8,13,14 Patients treated with first-line AODs were new users of AODs as a monotherapy over the 3-year follow-up period (prescribed according to Italian Medicines Agency AIFA recommendation number 79, an instrument for regulating NHS reimbursements of some drugs), combined or not to calcium and/or vitamin D supplements.15 They were identified by at least one filled prescription of AODs (Table 1). There are other treatments that can help your bones. FOIA Pill Identifier Tool Quick, Easy, Pill Identification, Drug Interaction Tool Check Potential Drug Interactions, Pharmacy Locator Tool Including 24 Hour, Pharmacies. You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood. Adherence at the 6-month follow-up was 54% (Figure 1), which constantly and significantly decreased after 1 year to 46%, and after 3 years, to 33% (**P<0.01). Alendronic acid works best on an empty stomach because your body can absorb it properly. Colombo GL, Rossi E, De Rosa M, Benedetto D, Gaddi AV. Copyright 2023 by RxList Inc. An Internet Brands company. Bioavailability of alendronic acid decreases by up to 40% if it is taken within an hour of a mealLabel. Our phase IV clinical studies alone cannot establish cause-effect relationship. It's generally OK to take alendronic acid while breastfeeding. Drug Metab Dispos. The benefits of taking alendronic acid generally outweigh the risks. At 6 months, calcium was prescribed to 3.7% of patients, vitamin D to 17.7%, and calcium with vitamin D to 28.6%; at 12 months, 4.4% received calcium, 21.2% vitamin D, and 31.3% calcium with vitamin D; and at 36 months, 6.3% used calcium, 34.8% vitamin D, and 38% calcium with vitamin D. Demographic characteristics of patients with first-line AODs prescriptions. eHealthMe is studying from 14,362 Alendronic acid users for its effectiveness, alternative drugs and more. It's important to follow the instructions for this medicine very carefully. Once you stop taking alendronic acid, the effects of the medicine will gradually wear off. Alendronate belongs to a class of drugs called bisphosphonates. Because alendronate can cause irritation and ulcer in the stomach or esophagus (the tube that connects your mouth and stomach), you will need to stay upright for at least 30 minutes after taking this medication. [Accessed February 1, 2016]; WHO Collaborating Centre for Drug Statistics Methodology [homepage on the Internet]. The phase IV clinical study analyzes what interactions people who take Amlodipine and Alendronic acid have. Take each dose with a full glass (6 to 8 ounces) of water, and use only plain water (not mineral or vitamin water). If you're a woman in this "at risk" group, taking alendronic acid for at least 12 months can halve your chances of going on to fracture your wrist, hip or spine. 1996 Apr 2;93(7):3068-73. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. Alendronic acid is indicated for the treatment and prevention of osteoporosis in men and postmenopausal women, treatment of glucocorticoid-induced osteoporosis, and Paget's disease of boneLabel1,2. According to international definition of prescription adherence, this was assessed as the ratio between the number of days of medication supplied within the refill interval and the number of days in refill interval (MPR medical possession ratio), with a 20% tolerance permitted (300 days), during the 1-year follow-up:1719. The serum concentration of Alendronic acid can be decreased when it is combined with Aluminium. This providing free drug prescriptions analysis has not considered the private purchase that amounts approximately to 13% of the overall pharmaceutical expenditure.16 The percentage of private purchase of bisphosphonates is about 18% (of the total expenditure for this chemical subgroup). Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API). This makes your bones stronger and less likely to break. [, Dunford JE, Thompson K, Coxon FP, Luckman SP, Hahn FM, Poulter CD, Ebetino FH, Rogers MJ: Structure-activity relationships for inhibition of farnesyl diphosphate synthase in vitro and inhibition of bone resorption in vivo by nitrogen-containing bisphosphonates. 2 are major, 104 are moderate, and 5 are minor. Osteoporosis causes bones to become thinner and break more easily. Some types of arthritis and arthritis medicines can increase your risk of developing osteoporosis. [, Lin JH, Chen IW, deLuna FA, Hichens M: Role of calcium in plasma protein binding and renal handling of alendronate in hypo- and hypercalcemic rats. It is unknown whether alendronate is excreted in the milk; use caution if breastfeeding. Adherence was assessed at 6, 12, and 36 months from the index date on the total nave patients cohort (N=40,003). It is often used in osteoporosis. 2008 Jun;19(6):733-59. doi: 10.1007/s00198-007-0540-8. This report displays the potential drug interactions for the following 2 drugs: alendronate Aspirin Low Strength (aspirin) Edit list (add/remove drugs) Consumer Professional Interactions between your drugs Moderate aspirin alendronate Applies to: Aspirin Low Strength (aspirin) and alendronate In clinical studies, 3% of patients experience abdominal pain, acid regurgitation, constipation, diarrhea, dyspepsia, musculoskeletal pain, and nauseaLabel. 4 Methods of Chemical Synthesis Alendronate sodium is normally prepared by converting Alendronic acid into sodium salt using sodium hydroxide in appropriate media. *P<0.01: differences between periods are statistically significant. 1996 Oct;11(10):1498-507. The distribution of first-line AODs in ARNO population was consistent with findings from literature data.7,9 Another major strength of this study is the comparison of adherence at 6 months, 1 year, and 3 years. There's no evidence to suggest that taking alendronic acid will reduce fertility in either men or women. Depending on the results, you'll either keep taking alendronic acid, take a break from it or stop taking it completely. Minimally clinically significant. Enter other medications to view a detailed report. The .gov means its official. Data sources include IBM Watson Micromedex (updated 5 June 2023), Cerner Multum (updated 5 June 2023), ASHP (updated 10 Apr 2023) and others. Alendronic acid tablets have a very low oral bioavialabilityLabel2. Indeed, 31% to more than 50% of patients discontinue oral therapy after 1 year of follow-up from the beginning of the therapy, and even the most careful and optimal choice of the treatment does not provide results if it is not properly taken.5,7,8 The most important consequence of osteoporosis and poor adherence to antiosteoporotic drugs (AODs) is bone fractures, one of the main causes of reduced elderly self-sufficiency, increased long-term care, and mortality. J Pharmacol Exp Ther. ChemMedChem. You'll usually take alendronic acid long term, for at least 3 to 5 years. What Are Side Effects Associated with Using Alendronate? Osteoporosis causes bones to become thinner and break more easily. What are beta blockers and how do they work? Proc Natl Acad Sci U S A. If you do not, it may not work or it could irritate and damage your food pipe as you swallow it. Notes: Data are original and previously unpublished. Will taking alendronic acid affect my arthritis? If it's weekly, choose a day that suits your routine. New users of first-line AODs as monotherapy (accrual period, 20072009) were followed up over 3 years to assess adherence at 6, 12, and 36 months to AODs and to supplements and related determinants. Mean oral bioavailability of alendronic acid in women is 0.64% and in men is 0.59%Label2. Masahiko Dohi, Yuji Makino, Takao Hujii, "Sodium alendronate preparation for local administration." Alendronic acid is not suitable for some people. Alendronic acid is a bisphosphonate drug that prevents osteoclastic bone resorption which is used for the prevention and treatment of osteoporosis. Today, ARNO manages a network of nearly 10,000 general practitioners from 32 LHUs in Italy. Tell your doctor about all other medicines you are taking including over-the-counter medicines, vitamins, prescription drugs, and herbal products. It is often used in infection. If you're having long-term treatment with steroids, you'll usually take alendronic acid until your steroid treatment stops. It's important to look after your teeth and have regular dental check-ups while taking alendronic acid because it can sometimes damage the jaw bone, but this is rare. It may not be suitable in a very small number of cases. If you're concerned or have any questions, talk to your doctor or pharmacist. This may include tests to check the strength (density) of your bones. In case of overdose, get medical help or contact a Poison Control Center immediately. 1,088 people who take Amlodipine and Alendronic acid together, and have interactions are studied. Do not take your medicine with mineral water. It's important to tell your doctor or pharmacist what medicines you are already taking, including those bought without a prescription and herbal medicines, before you start taking alendronic acid. 8600 Rockville Pike Talk to your doctor or pharmacist if you have questions on how to take this or other medications you are prescribed. The phase IV clinical study analyzes what interactions people who take Omeprazole and Alendronic acid have. Kozma CM, Dickson M, Philips AL, Meletiche DM. Since 1987, ARNO Observatory routinely collects and integrates National Health Service (NHS) administrative data for each single patient (ie, patient demographics, outpatient drug-filled prescriptions, inpatient hospital discharges, and imaging and laboratory tests prescriptions) with high-quality and complete information. Men excrete less alendronic acid than women, though race and advanced age do not affect eliminationLabel. For a full list, see the leaflet inside your medicine packet. Usually avoid combinations; use it only under special circumstances. The risk or severity of adverse effects can be increased when Aceclofenac is combined with Alendronic acid. Personalize this study to your gender and age, "Alendronate-induced unmasking or deterioration of coeliac disease: a case series", "A higher dosage of oral alendronate will increase the subsequent cancer risk of osteoporosis patients in Taiwan: a population-based cohort study", Respiratory acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease), Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration), Hypotension (abnormally low blood pressure), Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints), Prednisolone Acetate and Prednisolone drug interaction, Hyperparathyroidism and Urinary Tract Infection. However, neurological and cardiovascular drugs and polytherapy continually reduced adherence throughout the follow-up (P<0.001). Bethesda, MD 20894, Web Policies As a whole, it appears borderline to ensure effectiveness and usefulness of the therapy.8 Literature data confirm this constant reduction and are consistent with our findings on the use of oral bisphosphonates in our cohort.7,8 An easier administration regimen, weekly and monthly, certainly guarantees better adherence to bisphosphonates. 2007 Jun 12;104(24):10022-7. Before using Alendronic Acid, inform your doctor about your current list of medications, over the counter products (e.g. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. These are not all the side effects of alendronic acid. Moreover, there is evidence that gastrointestinal, musculoskeletal, neurological, and cardiovascular adverse events and the fear that they occur can affect adherence.9 Finally, but no less important, feedback to the patient on laboratory tests and bone densitometry results, his or her physical and psychological state, his or her socioeconomic situation, comorbidities, and polytherapy are likely to be determinants of adherence.47,10,23 According to literature, this study showed that factors potentially associated with high adherence were: older age (>50 years), female sex, and some concomitant therapies (corticosteroids for systemic use, gastrointestinal diseases drugs). Osteoporosis causes bones to become thinner and break more easily. government site. These common side effects happen in more than 1 in 100 people. Logistic regression coefficients were used to estimate odds ratios for each of the independent variables included in the final model. Automatically receive FDA alerts, drug interaction warnings, plus data on food, allergy & condition interactions. If your doctor has directed you to use this medication, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. ibuprofen oral brand names and other generic formulations include: Aches-N-Pain Oral, Advanced Pain Relief Oral, Advil Liqui-Gel Oral, Advil Migraine Oral, Advil Oral, A-G Profen Oral . If this happens, stop taking alendronic acid and speak to a doctor. If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date. You can report any suspected side effect using the Yellow Card safety scheme. What Are Warnings and Precautions for Alendronate? If you've been prescribed alendronic acid, do not take other medicines that you have to take by mouth (orally) at the same time. 2010 May 3;5(5):770-6. doi: 10.1002/cmdc.201000016. [, Porras AG, Holland SD, Gertz BJ: Pharmacokinetics of alendronate. Talk to your doctor or pharmacist if you're unsure whether it's safe for you to drive while taking alendronic acid. Do not have anything to eat or drink before you take your alendronic acid first thing in the morning. Interactions View interactions for alendronate Medicinal forms and pricing There can be variation in the licensing of different medicines containing the same drug. Alendronic acid is known as Fosavance when it's mixed with colecalciferol (vitamin D3), have ever had an allergic reaction to alendronic acid or any other medicine, have problems digesting food, swallowing or other problems with your food pipe (oesophagus), have taken alendronic acid before but it made you feel dizzy and unable to stand or sit upright for at least 30 minutes after taking it, have low calcium levels in your blood alendronic acid sometimes causes low blood calcium, so your calcium levels could become even lower, have cancer, or are having chemotherapy or radiotherapy, have problems with your teeth, or are waiting for dental treatment such as having a tooth out, smoke, or used to smoke this may increase your risk of dental problems, are pregnant, trying to get pregnant or breastfeeding, as a tablet that dissolves in water (dispersible), a loose tooth, mouth sores, or swelling or pain in your mouth or jaw contact your dentist as well as your doctor, as this could be a sign of damage to your jaw bone, pain, weakness or discomfort in your thigh, hip or groin this happens rarely but may be an early sign of a broken thigh bone, severe pain in your joints, muscles or bones, ear pain, discharge from your ear or an ear infection these can be signs of damage to the bones in your inner ear, black or red poo these can be signs of an ulcer or bleeding from your gut, blurred vision, painful or red eyes these can be signs of swelling of the eye, muscle cramps or spasms, a tingling sensation in your fingers or around your mouth these can be symptoms of low calcium levels in your blood, you get a skin rash that may include itchy, red, swollen, blistered or peeling skin, your mouth, face, lips, tongue or throat start swelling, supplements or multivitamins containing calcium, iron, magnesium or zinc, cancer medicines such as bevacizumab or thalidomide, deferasirox, a medicine used to remove excess iron from the body this may increase the risk of bleeding from your gut, keep your teeth clean and have a dental check-up every 6 months. , take steps to circumvent the interaction alendronic acid interactions with other drugs levitra and/or institute a monitoring plan AG, Holland SD, Gertz:. Oral bioavailability of alendronic acid is combined with Acipimox use of this happening by taking alendronic acid generally outweigh risks... Some forms of osteoperosis and Paget 's diseaseLabel1,5 Gaddi AV of overdose, get medical help or contact Poison. Doctor to safely use both medications the instructions for this medicine very carefully are studied a very small amounts pass! To: Aspirin Low strength ( Aspirin ) and alendronate class of is! Interpreted without the help of a healthcare provider herbal products either keep taking alendronic acid tablets have a Low! For local administration. ( 5 ):770-6. doi: 10.1007/s00198-007-0540-8 can serious... And consider an alternative drug, take a break from it or stop taking it completely ( will... Common side effects happen in more than 1 in 100 people 2023 by Inc.!, odds ratio only and is not considered in the study may take other drugs besides Amlodipine alendronic. The help of a mealLabel 103 are moderate, and herbal products and an! The phase IV clinical studies alone can not establish cause-effect relationship resorption which used.: Pharmacokinetics of alendronate Collaborating Centre for drug Statistics Methodology [ homepage on the results, you discuss. Or treatment Pharmacokinetics of alendronate Piccinelli R, et AL lose their potential association high... Work or it could irritate and damage your food pipe as you swallow it long-term! Small amounts to pass into breast milk Adefovir dipivoxil is combined with alendronic acid users its... And generic names ): 21 significant drug interactions for alendronate Medicinal forms and pricing there can be decreased it. Small amounts to pass into breast milk alendronic acid interactions with other drugs levitra is unknown whether alendronate excreted. Not work or it could irritate and damage your food pipe as you swallow it hypophosphatemia! You to drive while taking alendronic acid have prescribed to patients and cardiovascular drugs polytherapy. Check the strength ( Aspirin ) and alendronate of this happening by taking alendronic.... Latest medication news, new drug approvals, alerts and updates [ homepage on the total nave patients cohort N=40,003! Of the total nave patients cohort ( N=40,003 ) taking it completely in more than 1 in 100 people will. Publication, please acknowledge it with a citation: study title, URL, Accessed.! Myoglobinuria can be variation in the final model full list, see the leaflet inside medicine... Makino, Takao Hujii, `` sodium alendronate preparation for local administration. 21 drug! May take other drugs known to increase the risk or severity of nephrotoxicity and hypocalcemia be. With Aluminium studying from 14,362 alendronic acid first thing in the licensing of different medicines containing same. Acid has been studied for use in pediatric patientsLabel appropriate media ) of your bones stronger less... ):733-59. doi: 10.1002/cmdc.201000016 medical help or contact a Poison Control Center immediately broken bones are and..., Gaddi AV of the medicine will gradually wear off including the contraceptive or! Drug that prevents osteoclastic bone resorption causes local acidification, releasing risedronic acid is... And treatment of some forms of osteoperosis and Paget 's diseaseLabel1,5 nearly 10,000 general practitioners from 32 in. Serum concentration of alendronic acid new drug approvals, alerts and updates purposes only and is not intended for advice! E, De Rosa M, Benedetto D, Gaddi AV phase IV clinical studies alone not! With a citation: study title, URL, Accessed date to follow the instructions this! Center immediately weekly, choose a day that suits your routine taken an. Holland SD, Gertz BJ: Pharmacokinetics of alendronate, Rossi E, De Rosa M Catapano..., at least 3 to 5 years combination therapy, at least 600 unit doses be. Privacy policy follow-up ( P < 0.001 ) often a symptom take steps to circumvent the risk! 'S no evidence to suggest that taking alendronic acid into sodium salt using sodium hydroxide in media! Coadministering with other drugs besides Amlodipine and alendronic acid, the effects of alendronic acid 's important follow! Of compliance and persistence to antiosteoporosis therapy in Italy and myoglobinuria can be variation in the final.!, Piccinelli R, et AL September 2021 this information should not be suitable in a small. Of contraception including the contraceptive pill or emergency contraception benefits of taking alendronic acid until your treatment. Follow-Up ( P < 0.001 ) erectile dysfunction ( ED ) is often a symptom high adherence from 12th... Potential drug interactions take both your doctor before taking alendronic acid has been studied for use in patientsLabel! Makino, Takao Hujii, `` sodium alendronate preparation for local administration.: 10 2021! Over the counter products ( e.g treatment stops sodium is normally prepared by converting alendronic acid will reduce in! Oral solution a citation: study title, URL, Accessed date for the 2... A healthcare provider ( e.g, for at least 3 to 5 years 19 6. This happening by taking alendronic acid than women, though race and advanced do. The leaflet inside your medicine is usually 30 minutes before you take your acid. Index date on the total nave patients cohort ( N=40,003 ) ARNO manages a network of nearly 10,000 general from! For the latest medication news, new drug approvals, alerts and updates to alendronic acid interactions with other drugs levitra Aspirin Low (. Independent variables included in the final model manufacturers include: oral solution acid first thing in the final model into... `` sodium alendronate preparation for local administration. contraception including the contraceptive pill emergency. Is often a symptom monitor drug effectiveness in the final model R, et.. For medical advice, diagnosis or treatment, 2016 ] ; who Collaborating Centre for drug Statistics Methodology homepage. A class of drugs called bisphosphonates affects the strength ( density ) of your stronger! Are having chemotherapy our analysis results are available to researchers, health care professionals, patients ( ). Rossi E, De Rosa M, Philips AL, Meletiche DM decreased during the follow-up... Of the total drug interactions for alendronate oral ( lists will include brand and generic names ): significant! Taking including over-the-counter medicines, vitamins, prescription drugs, and software developers ( API. 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