I have not experienced weight gain during the time I have taken Prolia. You should also ask your doctor if Prolia is safe for you if you have or have had: Additionally, let your doctor know if youre pregnant or breastfeeding. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. Studies of Prolia didnt report weight gain as a side effect of the drug. What should I know about Prolia vs. Boniva? Courtney Sullivan, Certified Yoga Instructor, Debra Rose Wilson, Ph.D., MSN, R.N., IBCLC, AHN-BC, CHT. And your doctor can use this information to adjust your treatment plan if needed. Factors to consider include those listed below. Because Prolia can also cause low blood calcium, your risk may increase if you receive Prolia. Your doctor can discuss with you how to manage side effects and whether youll need to stop taking Prolia due to side effects. However, some people taking Prolia did have swelling in their arms or legs. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. Ill look for recommendations on this site. Weight gain (not a side effect) . Keep in mind that side effects of a drug can depend on: Additionally, you may experience different side effects from those listed below based on the condition youre treating with Prolia. For a basic overview of Prolia, including details about its uses, see this article. Talk with your doctor about the risks of using this drug during pregnancy. (2021). These problems may include: Your risk for mouth-related side effects may be higher if you have problems with your teeth. Its a place where people with certain conditions can find support and connect with others. You can often relieve mild pain in your back or bones with an over-the-counter (OTC) pain medication. For more information on this side effect, see Side effect specifics below. For a detailed breakdown of Prolia versus Xgeva, check out this article. Number of Prolia and Weight gain reports submitted per year: Time on Prolia when people have Weight gain *: Click here to view Gender of people who have Weight gain when taking Prolia*: Click here to view It is given when other medicines cannot be used or after other medicines did not work well. I would like to invite @ritafarmer, @mabel343, @kenzreggie, @bonnieh218, and @tessie to share any side-effects they, or a loved one, had or didn't have while taking Prolia. Theyll also usually treat the hypocalcemia right away. Introductory Offer: Save 10 percent on Cialis Together 4 pack - online only. Boniva contains the active drug ibandronate, but Prolia contains the active drug denosumab. If you cant properly absorb calcium or other minerals, be sure to talk with your doctor before using Prolia. If your doctor confirms you had a serious allergic reaction to Prolia, they may have you switch to a different treatment. People need calcium for bone health and other functions. But after these studies were done, some people have reported severe joint pain while using Prolia. At this point, I think I will probably go with Reclast despite hating that it will stay in my system for a year. Evenity is a once a month injection at the doctor's office and I recommend it for fewer side effects. Common side effects of Prolia can vary depending on which condition the drug is being used to treat. The doctor I saw after the fracture, recommended Prolia, rather than Forteo. No weight gain after three injections. What should I know about Prolia vs. Reclast? The list below may not include all possible serious side effects of the drug. Use of the terms female and male in this article refers to sex assigned at birth. Talk with them about your health and any concerns you have about Prolia and its effects. You should also contact your doctor or dentist if you experience pain or slow healing following dental surgery. If youd like to know more about the differences and similarities of Prolia and Evenity, see this comparison. Last medically reviewed on January 24, 2023. They do this by slowing the loss of minerals such as calcium from your bones. Factors to consider include those in the list below. https://www.medicalnewstoday.com/articles/prolia#side-effects. Prolia contains the active drug denosumab, and Reclast contains the active drug zoledronic acid. Biosimilars usually cost less than brand-name drugs. But hair loss has been reported by people who have taken Prolia since then. These treatments may include acetaminophen (Tylenol) or ibuprofen (Advil, Motrin). And if you have osteoporosis, falling could increase your risk of fractures. Take care. If youve noticed hair loss since starting Prolia treatment, talk with your doctor. Some dosage forms listed on this page may not apply to the brand name Prolia. In rare cases, your doctor may have you self-inject Prolia at home. This is a good discussion to accompany that discussion as this one could be focused on side-effects of Prolia. Problem absorbing minerals. No one in clinical trials of Prolia had to stop taking the drug due to dizziness. Untreated overactive or underactive parathyroid glands may lead to. Most side effects from Prolia are mild and can go away on their own within a few days or weeks. Talk with your doctor about your health history and discuss your risks with Prolia treatment. Theyll discuss with you other treatments to help protect you from fractures and bone loss. But alcohol can raise the risk of both osteoporosis and bone fractures. Your doctor can provide more information to you about the benefits and risks of using Prolia for your condition. Like most drugs, Prolia can cause an allergic reaction in some people. Like most drugs, Prolia may cause mild or serious side effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses. Musculoskeletal pain refers to pain in your bones, muscles, tendons, and ligaments. This is because your body doesnt make enough bone, or it loses bone faster than it makes new bone. The typical dose of Prolia is 60 mg under the skin once every 6 months. But weight gain may be a symptom of a side effect called peripheral edema. And with swelling, your body weight can be quickly increased. But tingling may be a symptom of side effects such as sciatica and hypocalcemia. Its possible, depending on the side effect. They may suggest a treatment that can raise your blood calcium to a suitable level. Although very rare, Prolia can cause serious dental problems and jaw-related side effects. They also include any added costs of the drug being given by a healthcare professional. Theyll need to confirm that you arent pregnant. Surgery on your thyroid or parathyroid. I know some people refuse to take these medications because of the side-effects and try to just use diet to achieve comparable results but I don't think that works, and in my opinion, even though there is some risk, the thought of a hip fracture is much worse. Our website services, content, and products are for informational purposes only. It comes as a liquid solution thats given as an injection. Bone turnover refers to how quickly your bones replace old bone tissue with new bone tissue. Save 2.20. Breastfeeding. RA is an autoimmune condition in which your immune system attacks your joints. Low blood calcium level. Is my risk for bone fractures higher if I leave my osteoporosis untreated instead of using Prolia? If youd like more information about Prolia use during pregnancy or while breastfeeding, talk with your doctor. Before you have any dental procedure, be sure to tell your dentist that youre using Prolia. Yes, your risk for bone fractures is higher if you leave osteoporosis untreated. Here are some frequently asked questions about the drugs side effects and their answers. 4 UNI | 4.95 per 1UNI. Youll receive Prolia doses from a healthcare professional. Prolia may be used off-label for RA, if you have a high risk for bone fractures. Here are a few questions to get you started: To learn more about Prolia, see these articles: To get information on different conditions and tips for improving your health, subscribe to any of Healthlines newsletters. In my case, based on my dexa results over a number of years, diet and all the calcium and vit k and d, in the world etc. Your doctor can check if you have osteoporosis, have low BMD, or have osteopenia by measuring your bone density. Pantoprazole is a proton pump inhibitor (PPI). Thyroid or parathyroid surgery. These supplements help to prevent a low calcium level while youre taking Prolia. With peripheral edema, fluid builds up in your body and causes swelling in your arms and lower legs. Your side effect notes can include things like: Keeping notes and sharing them with your doctor will help your doctor learn more about how the drug affects you. Although both drugs are approved to treat similar conditions, they work in different ways. Talk with your doctor about whether your kidney function is safe enough for you to use Prolia. Before beginning treatment with Prolia, be sure to tell your doctor about any dental work youve scheduled. Treating any mouth or dental problems early is the best way to help prevent serious dental complications. Serious side effects of Prolia that have been reported include: For most people, Prolias side effects are mild and go away after a few days to a few weeks. Theyll likely suggest other treatment options for your condition. If you experience swelling or are concerned about your weight while using Prolia, talk with your doctor. The Relationship Between Osteoporosis and Your Parathyroid Glands, Understanding How Steroids Cause Osteoporosis. But if they become bothersome, talk with your doctor or pharmacist. Keep reading to learn more. Weight gain wasnt reported as a side effect in studies of people using Prolia. This medicine may also be used to treat Zollinger-Ellison syndrome, a condition where the stomach produces too much acid. They may recommend ways to ease your symptoms and determine whether you should keep taking Prolia. For instance: Both Prolia and Forteo are given as injections under your skin. If they find any cavities or infection, theyll typically delay having you receive Prolia until your dental problems are treated. But the drug may also cause side effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses. Speak with your doctor if you have any side effect that bothers you or that does not go away. No, it doesnt cause weight gain. Its recommended that you take Prolia as prescribed by your doctor to prevent bone fractures if you have osteoporosis. (2022). If youre using Prolia and feel fatigued despite getting enough sleep, talk with your doctor. Serious side effects from Prolia arent common, but they may occur. They can recommend a treatment option other than Prolia. These side effects may be temporary, lasting a few days or weeks. Can diet and exercise reverse prediabetes? They can also happen if you have certain conditions or if you take certain medications. We link primary sources including studies, scientific references, and statistics within each article and also list them in the resources section at the bottom of our articles. Prolia is an injection prescribed for certain adults with osteoporosis, which is a condition that causes your bones to weaken. Diabetes and Osteoporosis: How Are They Related? Prolia contains the active drug denosumab, while Fosamax contains the active drug alendronate. Talk with your doctor about which other treatments are better choices for you. Forteo is given as a self-injection once daily. Before your appointment, write down questions, such as: How will Prolia affect my body, mood, or lifestyle? So mechanically good surgery, no consideration to tissue. This was one of the most common side effects in clinical trials of females who received Prolia for osteoporosis after menopause. For more information about the uses of Prolia, see the Is Prolia used for osteoporosis? and Is Prolia used for other conditions? sections below. Lifestyle changes that can help improve cholesterol levels include exercising regularly and eating a healthy diet. I would like to know if anyone else in my age range has experienced significant weight gain with the first shot. (With off-label use, a drug is used to treat conditions other than those its been approved to treat.) itchy, dry skin. These medications have different active ingredients and they belong to different groups of drugs. If youre concerned about weight gain with Prolia, talk with your doctor. Muscle pain often contributes to back pain, one of the most common side effects reported in clinical trials of Prolia. Specifically, its used to increase bone mass in: Osteopenia (low bone mass), and low bone mineral density (BMD) can occur with older age. This aids in keeping your calcium level within the recommended range. Below, we answer some common questions about taking Prolia. 2023 Healthline Media LLC. Write a review. Its important to discuss all your concerns with your doctor. Others may continue for as long as you take the drug, but they can be easily managed. According to the American Dental Association, your risk of this problem may increase if you receive denosumab (the active drug in Prolia) for longer than 2 years. These are just a few of the more common side effects reported by people who took Prolia in studies. You may also want to check out the online communities at Bezzy. This may cause teeth to become loose and need to be removed. If youve had surgery on one of these glands, tell your doctor before you begin treatment with Prolia. * In this article, we use the terms male and female to refer to someones sex assigned at birth. Your doctor or pharmacist can tell you more about the potential side effects of Prolia and ways to reduce them. They can help you decide whether the possible benefits for your condition outweigh your risks for serious side effects. If you have new or unusual pain in your hip, thigh, or groin, your doctor will likely have you temporarily stop Prolia. Doctors sometimes prescribe Prolia to treat osteoporosis and bone thinning. Instead, your doctor may recommend that you make certain changes to your diet, such as increasing your calcium and vitamin D intake. As with most drugs, Prolia can cause an allergic reaction in some people. Both medications are injected under the skin of the stomach, thigh, or upper arm, but the doses of each are different. If you have any questions about Prolias side effects, talk with your doctor. Complete your request online or contact us by phone. - Weight gain with Prolia https: . Rare, long-term side effects of Prolia include fractures of the spine or femur (thighbone). Before you begin treatment with Prolia, your doctor should examine your mouth. Prolia isnt known to cause any harmful interactions with alcohol. They can give you more details about this possible side effect and suggest ways to manage it. Nonmetastatic means the cancer hasnt spread to other areas of the body. And generic Boniva may be as low as $ 14.00 for a 3-month supply (three tablets) with a free GoodRx discount. As mentioned above, Prolia contains the active drug denosumab. Most Medicare plans and other insurance plans cover Prolia. I would", "@kellyhahn1 @laura1965 I apologize if somewhere I gave the impression that I had used Prolia, I", "JK, someone on another site I follow (called Prolia Side Effects on FB) mentioned that she", "just had my 2nd prolo. Nausea can sometimes be a symptom of severe constipation. If you can become pregnant, you should use an effective form of birth control during Prolia treatment. upper respiratory tract infections, such as the, decreased bone production (bones take longer to form new tissue), swelling under your skin, typically in your eyelids, lips, hands, or feet, swelling of your mouth, tongue, or throat, which can make it hard to breathe, an antihistamine that you take by mouth, such as, a product you apply to your skin, such as hydrocortisone cream, what dose of drug you were taking when you had the side effect, how soon after starting that dose you had the side effect, what your symptoms were from the side effect, what other medications you were also taking, any other information you feel is important. With these reports, it wasnt known whether Prolia or something else (such as a different medication) caused the hair loss. If youre able to become pregnant, your doctor will order a pregnancy test for you before you take Prolia. The UK is the first country to allow OTC access to Sanofi's tadalafil-based erectile dysfunction drug Cialis following a successful switch. Its given to adults who are at high risk for bone fractures. If you notice any tooth or jaw pain, or sensitivity while using Prolia, talk with your doctor or dentist right away. This can help prevent dental and jaw-related side effects that Prolia might cause. Your doctor may suggest limiting foods that are high in trans fats, such as fried foods. (Biosimilars are like generic drugs. This is because the drug may be harmful to a growing fetus. You should talk with your doctor if you develop any mild side effects that concern you. * Sex and gender exist on spectrums. For information about the difference between sex and gender, see this article. Skipping a dose of Prolia or stopping use of the drug increases the risk of bone fractures. Diabetes and osteoporosis are comorbidities that impact each other. (To learn more, see the Precautions for Prolia section below.). Started prolia last year, had a fall back in 2000 but back pain now is severe, just started flexeril, weight gain because I stay hungry all the time, head itches, mouth has sores in it & 1 outside that doesn't heal, more easily stressed & agitated easy, hysterectomy when I was 27,hands r numb when I have them at rest a couple hours & swell where. Dizziness from Prolia is usually mild and may go away on its own within a few days or weeks. You shouldnt use Prolia if youre pregnant or planning to become pregnant. Musculoskeletal pain from Prolia is mild or manageable for most people. The conditions and factors to consider include: Upcoming dental procedures. While using Prolia, contact your doctor right away if you notice new or unusual pain in your hip, thigh, or groin. A severe jawbone problem called osteonecrosis has rarely been reported with Prolia. Talk with your doctor if you have trouble absorbing minerals before you use Prolia. But Zometa contains the active drug zoledronic acid. All rights reserved. For more information about Prolia, including details about its uses, see this in-depth article on the drug. Mild side effects of Prolia that have been reported include: Mild side effects of many drugs may go away within a few days or a few weeks. If your pain doesnt ease with OTC options, your doctor may suggest prescription pain medication. Fosamax and Prolia both contain medications that are used to treat osteoporosis . Pain, specifically musculoskeletal pain, is one of the most common side effects of Prolia. Prolia comes with a warning about a low level of calcium in the blood. You should always consult your doctor or another healthcare professional before taking any medication. Your doctor or pharmacist can tell you about any interactions these may cause with Prolia. Other side effects may continue for as long as you receive the medication, but they can often be relieved with other treatments. Youll receive Prolia doses from a healthcare professional. It is a bisphosphonate in pill form and if it gives you any problems at least you can stop taking it. weight is up 3 lbs, i'm eating an amount that would normally drop my weight and running more but no weight loss. * Sex and gender exist on spectrums. Women going through menopause have a higher risk of developing osteoporosis. Note: After the Food and Drug Administration (FDA) approves a drug, it tracks and reviews side effects of the medication. Its a, Forteos active ingredient is teriparatide. I've had other issues with Prolia and have to make a decision very soon whether to have no.4, or have the infusion of Reclast . They include bone pain, back pain, and a higher risk of certain infections. Call your doctor right away if you have an allergic reaction to Prolia. They may be able to recommend ways to help reduce this side effect. Description and Brand Names Drug information provided by: IBM Micromedex US Brand Name Prolia Xgeva Descriptions Denosumab injection is used to treat osteoporosis (thinning of the bones) in women who have an increased risk for fractures after menopause, and osteoporosis in men. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. * Symptoms can include: flushing (temporary warmth, redness, or deepening of skin color), swelling under your skin, typically in your lips, eyelids, feet, or hands, swelling of your mouth, tongue, or throat, which can make it hard to breathe. Certain prescription steroids may cause osteoporosis by how your body accesses its stores of calcium and vitamin D. Osteoporosis and degenerative disk disease (DDD) are unique conditions that may be related. * This side effect was reported only in females using Prolia to treat osteoporosis after menopause. (Prolia injections are only given by a healthcare professional.). Having dental procedures, including tooth extractions, during Prolia treatment may increase your risk of dental side effects. Tingling or numbness in the hands, feet, and face can develop as a symptom of severe hypocalcemia. Overactive or underactive parathyroid glands, tell your doctor before you begin treatment with.... Need to be removed received Prolia for your condition to become loose and need to be removed in some.. Peripheral edema ) or ibuprofen ( Advil, Motrin ) of both osteoporosis and bone.! Did have swelling in your hip, thigh, or lifestyle these glands, tell dentist. Osteoporosis, falling could increase your risk may increase your risk of fractures suggest other treatment for! 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Its a place where people with certain conditions or if you have any about..., Understanding how Steroids cause osteoporosis more about the risks of using Prolia, see the Prolia... One in clinical trials of Prolia Rose Wilson, Ph.D., MSN,,! They work in different ways for osteoporosis keeping your calcium and vitamin D intake the female... Month injection at the doctor I saw after the Food and drug Administration ( FDA ) approves a,... Your doctor if you cant properly absorb calcium or other minerals, be sure tell... Help protect you from fractures and bone fractures if you experience swelling or are about! And vitamin D intake on their own within a few days or weeks to adjust your treatment plan needed! Healthy diet use this information to you about any interactions these may cause mild or serious effects. Studies of Prolia didnt report weight gain as a liquid solution thats as... Focused on side-effects of Prolia is usually mild and may go away ease with OTC options, your may. 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