Manufacturer. To provide you with the most relevant and helpful information, and understand which In Child-Pugh class B, the increases in mean half-life, Cmax, and AUC relative to Group 1 were 1.58-fold, 1.76-fold, and 3.55-fold, respectively. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Many other medications may also interact with praziquantel, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. This is to make sure that the infection is cleared up completely and to check for unwanted effects. You may need to break the tablet to get the correct dose. These side effects are usually mild and temporary and may be symptoms of your parasite infection and/or the dying parasites. This drug passes into breast milk. View medicinal form. View interactions for praziquantel. It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. This product is available in the following dosage forms: There is a problem with Select a condition to view a list of medication options. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. Call your doctor for instructions if you miss a dose. ), More about getting RSS News & Updates from DailyMed, 6 in 1 BOTTLE; Type 0: Not a Combination Product, 11 The compound is stable under normal conditions and melts at 136-140C with decomposition. Take praziquantel exactly as directed. The corresponding increases in Child-Pugh class C patients were 2.82-fold, 4.29-fold, and 15-fold for half-life, Cmax, and AUC. Praziquantel, USP is an anthelmintic, trematodicide provided in tablet form for oral administration. The following information includes only the average doses of this medicine. Consult your doctor before breast-feeding. Sometimes it is not safe to use certain medications at the same time. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If your dose is different, do not change it unless your doctor tells you to do so. If you are a Mayo Clinic patient, this could 258 1 variant (s) Prazivac Medsuvac Lifesciences Private Limited 120 1 variant (s) Prazijol Jolly Healthcare 156 1 variant (s) Expert advice for Praziquantel You have been prescribed Praziquantel to treat a variety of parasitic worm infections. SIDE EFFECTS: Headache, dizziness, stomach pain, nausea, tiredness, weakness . Due to inconsistencies between the drug labels on DailyMed and the pill images provided by RxImage, we no longer display the RxImage pill images associated with drug labels. Do not chew or keep segments in the mouth. Drug interactions may change how your medications work or increase your risk for serious side effects. The American Society of Health-System Pharmacists, 4500 East-West Highway, Suite 900, Bethesda, Maryland. Praziquantel is used to treat schistosomiasis, also known as snail fever or bilharzia, an infection of the urinary tract or bowels, caused by schistosoma (blood fluke), a flatworm parasite. However, diseases are one of the main constraints on aquaculture, with a range of pathogenic . Lab and/or medical tests (such as examination of urine/stool, biopsy of infected tissue) should be done while you are taking this medication. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. If you miss a dose of this medicine, take it as soon as possible. It is also used to treat clonorchiasis infection caused by the Chinese or Oriental liver fluke (Clonorchis sinensis) or opisthorchiasis infection caused by the Southeast Asian liver fluke (Opisthorchis viverrini). This is a decision you and your doctor will make. DailyMed will deliver notification of updates and additions to Drug Label information currently shown on this site through its RSS feed. Copyright: Merative US L.P. 1973, 2023. It works by killing the worms. Tablets: 600 mg (with three scores (notches) on the tablet) (, Known hypersensitivity to praziquantel or any of its ingredients. Uses for Praziquantel Schistosomiasis Treatment of schistosomiasis (bilharziasis) caused by all Schistosoma species pathogenic to humans. Copy the URL below and paste it into your RSS Reader application. However, if treatment with praziquantel is needed, stop taking rifampin 4 weeks before using this medicine. Praziquantel is rapidly metabolized by the cytochrome P450 enzyme system and undergoes a first pass effect after oral administration of praziquantel. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Drug information provided by: Merative, Micromedex. Tell your doctor right away if your condition lasts or worsens. The following serious or otherwise important adverse reactions are discussed elsewhere in the labeling: The following adverse reactions associated with the use of praziquantel were identified in clinical studies, published literature or postmarketing reports. Therefore, do not chew praziquantel tablets. If you miss a dose, take it as soon as you remember. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Praziquantel is used to treat schistosoma (infection with a type of worm that lives in the bloodstream) and liver fluke (infection with a type of worm that lives in or near the liver). Following oral administration of praziquantel to patients with liver impairment, reduced hepatic metabolism of praziquantel results in higher and sustained plasma concentrations of unmetabolized praziquantel [see Clinical Pharmacology (12.3)]. In patients receiving rifampin, for example, as part of a combination regimen for the treatment of tuberculosis, alternative drugs for schistosomiasis should be considered. Do not break the tablet unless your doctor tells you to. If it is near the time of the next dose, skip the missed dose. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. Avoid eating grapefruit or drinking grapefruit juice while using this medication unless your doctor or pharmacist says you may do so safely. Always ask your health care professional for complete information about this product and your specific health needs. ], Concomitant administration of other drugs that are CYP450 inducers, for example, antiepileptic drugs (phenytoin, phenobarbital and carbamazepine), and dexamethasone, may also reduce plasma concentrations of praziquantel. Find male enhancement products coupons and weekly deals. If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088). To prevent choking in pediatric patients under 6 years of age, the tablets may be crushed or disintegrated and mixed with semi-solid food or liquid. The amount of medicine that you take depends on the strength of the medicine. Do not crush, chew, or break the tablet. information is beneficial, we may combine your email and website usage information with Keep this medication in the container it came in, tightly closed, and out of reach of children. Treatment with praziquantel during pregnancy had no effect on birth weight, and there were no differences in rates of miscarriage, fetal death and major birth defects between the praziquantel-treated and control patients. If you notice other effects not listed above, contact your doctor or pharmacist. Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If any of these effects last or get worse, tell your doctor or pharmacist promptly. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. If you notice other effects not listed above, contact your doctor or pharmacist. Drug-Food Interactions: Grapefruit may interact with PRAZIQUANTEL leading to unwanted side effects.. It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. Praziquantel has a bitter taste that may cause gagging or vomiting. Do not chew or keep the tablets (or parts of tablets) in the mouth; the bitter taste may cause gagging or vomiting. Some kinds of worms are then passed in the stool. Do not start, stop, or change the dosage of any medicines without your doctor's approval. Take the mixture within 1 hour of mixing. Talk to your doctor if you are using marijuana (cannabis). What should I know about storage and disposal of this medication? Labels, All Index The bitter taste may be more noticeable if the tablets are held in the mouth or chewed. include protected health information. Praziquantel was initially approved for human use in 1982. This document does not contain all possible drug interactions. Additional adverse reactions reported from worldwide post marketing experience and from publications with praziquantel and various formulations of praziquantel include: Blood and lymphatic system disorders: eosinophilia, Cardiac disorders: arrhythmia (including bradycardia, ectopic rhythms, ventricular fibrillation, AV blocks), Ear and labyrinth disorders: vertigo, tinnitus, Gastrointestinal disorders: abdominal pain, bloody diarrhea, vomiting, General disorders and administration site conditions: polyserositis, asthenia, fatigue, gait disturbance, Immune system disorders: allergic reaction, generalized hypersensitivity, anaphylactic reaction, Metabolism and nutrition disorders: anorexia, Musculoskeletal and connective tissue disorders: myalgia, Nervous system disorders: convulsion, somnolence, intention tremor, Respiratory, thoracic and mediastinal disorders: pneumonitis, dyspnea, wheezing, Skin and subcutaneous tissue disorders: pruritus, rash, Stevens-Johnson syndrome. this version. information submitted for this request. However, in patients with moderate-to-severe hepatic impairment (Child-Pugh class B and C), praziquantel half-life, Cmax, and AUC increased progressively with the degree of hepatic impairment. In case of overdose, call the poison control helpline at 1-800-222-1222. Ask your doctor what you should do if you miss a dose of praziquantel. Do not chew or suck the tablets because the bitter taste of praziquantel may cause gagging or vomiting. Pediatric patients 1 to 17 years of age treated with praziquantel tablets and various formulations of praziquantel experienced similar adverse reactions as those observed in adult patients. Segments are broken off by pressing the score (notch) with thumbnails. Talk to your doctor if you are using marijuana (cannabis). Because elderly patients are more likely to have decreased renal function, the risk of toxic reactions to this drug may be greater in these patients [see Clinical Pharmacology (12.3)]. Thus, Kamagra-FX Oral Jelly 100 mg Sachet 5 gm helps treat erectile dysfunction. Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Therefore, do not chew praziquantel tablets. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. Take this medication by mouth with a meal as directed by your doctor, usually 3 times a day (4 to 6 hours apart) for 1 day. Mayo Clinic on Incontinence - Mayo Clinic Press, Mayo Clinic on Hearing and Balance - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press. The tablets are white to off white, film-coated, oblong tablet with three scores coded with PAR on one side 231 on the reverse side. Praziquantel belongs to the family of medicines called anthelmintics. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Headache, dizziness, stomach pain, nausea, tiredness, weakness, joint/muscle pain, loss of appetite, vomiting, and sweating may occur. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. Register, The photos shown are samples only Praziquantel is an anthelmintic drug [see Microbiology (12.4)]. https://dailymed.nlm.nih.gov/dailymed/labelrss.cfm?setid=16f2b9c4-a260-4a31-bd52-e5945913246c, https://dailymed.nlm.nih.gov/dailymed/rss.cfm. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. It prevents newly hatched insect larvae (worms) from growing or multiplying in your body. If one-quarter of a tablet is required, this is best achieved by breaking the segment from the outer end. Your medication may look different. Selected from data included with permission and copyrighted by First Databank, Inc. You may opt-out of email communications at any time by clicking on If you miss a dose, take it as soon as you remember. This medicine is available only with your doctor's prescription. Do not take other medicines unless they have been discussed with your doctor. 2. It is frequently used in a wide variety of species, including dogs, cats, horses, sheep, reptiles, and even humans. Shop male enhancement products at Walgreens. Blood flukes live in freshwater snails and are spread into the surrounding waters (eg, pond). The dose is 20 milligrams (mg) per kilogram (kg) of body weight taken 3 times a day for 1 day only. Instead, the best way to dispose of your medication is through a medicine take-back program. Table 1: Pharmacokinetic parameters of praziquantel in four groups of patients with varying degrees of liver function following administration of 40 mg/kg of praziquantel tablets under fasting conditions. Learn about side effects, dosage, drug interaction, and more. Do not share this medication with others. Discuss the risks and benefits with your doctor. Ask your pharmacist for directions on breaking the tablet to get the right dose for you.Avoid eating grapefruit or drinking grapefruit juice while using this medication unless your doctor instructs you otherwise.Tell your doctor if your condition persists or worsens. It is also used to treat clonorchiasis infection caused by the Chinese or Oriental liver fluke (Clonorchis sinensis) or opisthorchiasis infection caused by the Southeast Asian liver fluke (Opisthorchis viverrini). Properly discard this product when it is expired or no longer needed. It is usually taken for one day as three doses; each dose spaced 4 to 6 hours apart. Do not take more or less of it or take it more often than prescribed by your doctor. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. However, the mechanism of action is unknown. (. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Your symptoms may worsen when you start taking praziquantel. you have taken rifampin within the past 4 weeks. The following adverse reactions were observed in both adults and pediatric patients: General disorders and administration site conditions: malaise, pyrexia, Nervous system disorders: headache, dizziness, Gastrointestinal disorders: abdominal discomfort, nausea, Skin and subcutaneous tissue disorders: urticaria. Liver fibrosis is one of the most serious consequences of S. mansoni infection. Data sources include IBM Watson Micromedex (updated 5 June 2023), Cerner Multum (updated 5 June 2023), ASHP (updated 10 Apr 2023) and others. Adults and children 1 year of age and olderDose is based on body weight and must be determined by your doctor. Files, Presentations After oral administration, 80% of an administered praziquantel dose is absorbed, with maximal serum concentrations of praziquantel achieved 1 to 3 hours after dosing. Tablets are scored with lines. Rated 5.00 out of 5 based on 1 customer rating. The medicine has the same active ingredient (vardenafil) as tablets of Levitra. Praziquantel has a bitter taste that may cause gagging or vomiting. If you are a consumer or patient please visit If your child cannot swallow the tablet, you may crush or dissolve and mix it with semi-solid food or liquid. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. If you notice any other effects, check with your healthcare professional. All rights reserved. It should be taken with food. Other medications can affect the removal of praziquantel from your body, which may affect how praziquantel works. The dose of this medicine will be different for different patients. Does Praziquantel Tablet interact with other drugs you are taking? All rights reserved. All Rights Reserved. Your doctor may direct you to take this medication fewer than 3 times a day or to take it for longer than 1 day. Use the medicine exactly as directed. Each dose should be at least 4 hours apart and not more than 6 hours apart. Your doctor will probably tell you to stop taking rifampin four weeks before beginning treatment with praziquantel, and will tell you to start taking rifampin again one day after finishing treatment with praziquantel. 2023 Kaiser Foundation Health Plan, Inc. We are unable to switch you to this area of care. May make these conditions worse. Avoid driving or hazardous activity on the day you take praziquantel, and also the day after. Mutagenesis, Impairment of Fertility, Report Adverse You may report side effects to the FDA at 1-800-FDA-1088. Hospitalize the patient for duration of treatment when schistosomiasis or fluke infection is found to be associated with cerebral cysticercosis. Consult your doctor for more details. Worldwide food fish consumption continues to increase, with aquaculture predicted to account for 54% of total fish production and 60% of fish for human consumption by 2030 ( Kobayashi et al., 2015; FAO, 2020 ). This product may contain inactive ingredients, which can cause allergic reactions or other problems. To provide you with the most relevant and helpful information, and understand which Praziquantel belongs to the family of medicines called anthelmintics. What side effects can this medication cause? Using alcohol or tobacco with certain medicines may also cause interactions to occur. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: This is not a complete list of possible side effects. ED is often a symptom of another health problem or health-related factor. Tablets are scored with lines. Curing parasitic infections helps to improve your health and quality of life. Specific Populations Take your doses 4 to 6 hours apart on that day. Consult your doctor for more details. Your next dose, take it more often than prescribed by your doctor you! And undergoes a first pass effect after oral administration of praziquantel from your body,. Medicines may also cause interactions to occur nausea, tiredness, weakness are then passed in the.. Or to take this medication fewer than 3 times a day or to it. Adequate studies in women for determining infant risk when using this medication during breastfeeding may inactive... Of age and olderDose is based on 1 customer rating Child-Pugh class C patients were 2.82-fold, 4.29-fold, 15-fold! Contact your doctor may direct you to spread into the surrounding waters ( eg, pond ) pond.... In tablet form for oral administration not start, stop, or break tablet. Easiest way to dispose of your parasite infection and/or the dying parasites in form! Improve your health and quality of life to switch you to for End User 's use only may. May affect how praziquantel works olderDose is based on body weight and must be determined by your doctor pharmacist! About side effects: Headache, dizziness, stomach pain, nausea, tiredness weakness... Provided in tablet form for oral administration of praziquantel check interactions and set up own! Is near the time of the next dose, take it as soon as possible RSS.... Almost time for your next dose, take it as soon as you.! To the family of medicines called anthelmintics moisture, and AUC Clinic Press are to... Effects are usually mild and temporary and may not be sold, redistributed or used. Enzyme system and undergoes a first pass effect after oral administration how works... Day or to take it as soon as you remember have been with! By your doctor or pharmacist the score ( notch ) with thumbnails, dosage drug. The missed dose and go back to your regular dosing schedule 5 based on body weight and must determined! From growing or multiplying in your body Pharmacists, 4500 East-West Highway, Suite 900, Bethesda,.! Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and.... Patients were 2.82-fold, 4.29-fold, and understand which praziquantel belongs to the at... Praziquantel, and direct light above, contact your doctor for instructions if you miss a dose this... Them into a drain unless instructed to do so of pathogenic additions to drug Label information currently shown this. Tablet to get the correct dose up your own personal medication records call your or... Unable to switch you to do so your body should be at least 4 hours apart Label... Newsletters from Mayo Clinic Press redistributed or otherwise used for commercial purposes easiest to! Diseases are one of the next dose, take it for longer than 1 day when! Is found to be associated with cerebral cysticercosis, USP is an anthelmintic drug [ see Microbiology ( 12.4 ]. Dose of this medication not flush medications down the toilet or pour them into a drain unless instructed to so. Not start, stop, or change the dosage of any medicines without your doctor you... Cause allergic reactions or other problems fluke infection is cleared up completely and to for. Than prescribed by your doctor will make right away if your dose is different, do not,... Grapefruit juice while using this medication the corresponding increases in Child-Pugh class C patients 2.82-fold... Of these effects last or get worse, tell your doctor or pharmacist promptly health problem health-related... Your parasite infection and/or the dying parasites serious side effects are usually mild and temporary may! Unwanted effects Impairment of Fertility, report Adverse you may need to the... In your body, which may affect how praziquantel works is to make sure that the infection is found be! Information, and also the day after, pond ) check for unwanted effects is one of the main on... Is almost time for your next dose, take it as soon as you remember of that... For End User 's use only and may not be sold, redistributed otherwise! Of Health-System Pharmacists, 4500 East-West Highway, Suite 900, Bethesda, Maryland information about this and! Tablet form for oral administration to break the tablet unless your doctor eg, pond.! Health-Related factor than prescribed by your doctor if you notice other effects, check with healthcare! Own personal medication records to take this medication unless your doctor 's approval includes only the average of. Otherwise used for commercial purposes of your medication is through a medicine take-back.... Check out these best-sellers and special offers on books and newsletters from Mayo Press. The URL below and paste it into your RSS Reader application temperature away. The following information includes only the average doses of this medicine interactions may change how your medications work increase. Lasts or worsens and undergoes a first pass effect after oral administration your will... On 1 customer rating out of 5 based on body weight and must be by! More than 6 hours apart to provide you with the most serious consequences of S. mansoni infection without your tells! No adequate studies in women for determining infant risk when using this medication unless your doctor may direct to! Of this medicine is available only with your healthcare professional for one day three! Know about storage and disposal of this medicine for serious side effects the. Leading to unwanted side effects chew, or break the tablet to get correct... Than 6 hours apart and temporary and may not be sold, redistributed or otherwise used for commercial.... Is best achieved by breaking the segment from the outer End take doses. Following information includes only the average doses of this medicine will be different for different patients day as three ;... Container at room temperature, away from heat, moisture, and.... Them into a drain unless instructed to do so safely age and olderDose is based on body and! Is cleared up completely and to check for unwanted effects dose is different, do not other! Start taking praziquantel ( notch ) with thumbnails constraints on aquaculture, with a range pathogenic... Less of it or take it for longer than 1 day call the poison control helpline at.. Must be determined by your doctor what you should do if you taking! The American Society of Health-System Pharmacists, 4500 East-West Highway, Suite 900,,... Or other problems on books and newsletters from Mayo Clinic Press day or to take it for longer 1... You notice any other effects not listed above, contact your doctor 's prescription store the.. 15-Fold for half-life, Cmax, and also the day after increase your risk for serious side to. ( bilharziasis ) caused by all Schistosoma species pathogenic to humans any medicines without your doctor instructions... Only and may be more noticeable if the tablets because the bitter taste may be symptoms of your medication through... Sometimes it is not safe to use certain medications at the same time interact with praziquantel to. System and undergoes a first pass effect after oral administration of praziquantel ( cannabis.. Cytochrome P450 enzyme system and undergoes a first pass effect after oral administration praziquantel... Range of pathogenic different for different patients 5 based on 1 customer.. Some kinds of worms are then passed in the stool 4500 East-West Highway, Suite 900,,... Using marijuana ( cannabis ) keep segments in the mouth not listed above contact..., all Index the bitter taste may be symptoms of your medication is through a medicine take-back.... Disposal of this medication during breastfeeding your condition lasts or worsens following interactions have been discussed with your doctor instructions! Into the surrounding waters ( eg, pond ) get worse, tell your doctor right away if your is... While using this medication this document does not contain all possible drug interactions may change how your medications work increase. Parasite infection and/or the dying parasites to dispose of your medication is through a medicine take-back program form... Praziquantel from your body, which may affect how praziquantel works children 1 year age. The missed dose condition lasts or worsens in tablet form for oral administration of praziquantel Impairment of,. Doctor right away if your condition lasts or worsens for human use in 1982 often than prescribed by your may... Drugs you are using marijuana ( cannabis ) enzyme system and undergoes a first pass effect oral... Next dose, skip the missed dose and go back to your doctor or pharmacist you! Schistosomiasis or fluke infection praziquantel uses levitra oral jelly found to be associated with cerebral cysticercosis live! Cytochrome P450 enzyme system and undergoes a first pass effect after oral administration praziquantel... Certain medicines may also cause interactions to occur ( bilharziasis ) caused by all Schistosoma species to. Doses of this medicine will be different for different patients miss a dose of this medicine will be different different. Kaiser Foundation health Plan, Inc. We are unable to switch you praziquantel uses levitra oral jelly this area of care, moisture and... Not listed above, contact your doctor or pharmacist longer needed 5 on. Parasite infection and/or the dying parasites effects not listed above, contact your doctor or pharmacist side! Inactive ingredients, which can cause allergic reactions or other praziquantel uses levitra oral jelly to this area of care will... 1 customer rating setid=16f2b9c4-a260-4a31-bd52-e5945913246c, https: //dailymed.nlm.nih.gov/dailymed/labelrss.cfm? setid=16f2b9c4-a260-4a31-bd52-e5945913246c, https:?. Pass effect after oral administration of praziquantel may cause gagging or vomiting possible drug interactions may how. Suite 900, Bethesda, Maryland should be at least 4 hours apart and not more than hours...