The applesauce should not be hot and should be soft enough to be swallowed without chewing. US residents can call their local poison control center at 1-800-222-1222. Children 1 to 16 years of ageDose is based on body weight and must be determined by your doctor. Uncomplicated ulcers usually heal after discontinuation of NSAIDs and treatment with standard dosages of PPIs, H2 blockers, or sucralfate (Carafate). After the tablet has dissolved, it can be swallowed with or without water. It is left to the treating physician to determine which approach is most appropriate. The https:// ensures that you are connecting to the Carafate vs. omeprazole: What's the difference? This may reduce the effectiveness of ketoconazole or increase digoxin toxicity. Store at room temperature away from light and moisture. Before taking omeprazole, tell your doctor or pharmacist if you are allergic to it; or to similar drugs (such as esomeprazole, lansoprazole, pantoprazole); or if you have any other allergies. Mayo Clinic does not endorse companies or products. If it is near the time of the next dose, skip the missed dose. This includes prescription (eg, atazanavir, nelfinavir, Reyataz, Viracept) or nonprescription (over-the-counter [OTC]) medicines and herbal (eg, St. John's wort) or vitamin supplements. USES: Omeprazole is used to treat certain stomach and esophagus problems (such as acid reflux, ulcers). Answered by Dr. Brian Staiger, PharmD Swallow the capsule and tablet forms of omeprazole whole. The newer agents, rabeprazole and pantoprazole, seem to have fewer drug interactions. Prolonged use also reduces absorption of vitamin B12 (cyanocobalamin). However, elderly patients are more sensitive to the effects of this medicine than younger adults. Systemic lupus erythematosus (SLE)Use with caution. Gut. are known to interact with 8600 Rockville Pike Do not increase your dose or take this drug more often than directed. Cialis will compete against Viatris' sildenafil-based Viagra Connect in the men's sexual health and wellness category, which has seen a proliferation of . Constipation is the most frequent side effect. Do not double the dose to catch up. Omeprazole is used to treat the following conditions: Barrett's Esophagus Duodenal Ulcer Erosive Esophagitis Gastritis/Duodenitis (off-label) GERD Helicobacter Pylori Infection Hiatal Hernia (off-label) Indigestion Laryngopharyngeal Reflux (off-label) Multiple Endocrine Adenomas Stomach Ulcer Systemic Mastocytosis Zollinger-Ellison Syndrome It works by decreasing the amount of acid your stomach makes. Omeprazole and sucralfate in the treatment of NSAID-induced gastric and duodenal ulcer The results of this study show that omeprazole is superior to sucralfate in healing NSAID-induced gastroduodenal ulcer in patients who continue to take anti-inflammatory drugs. Proton pump inhibitors are used for the treatment of conditions such as ulcers, gastroesophageal reflux disease (GERD) and the Zollinger-Ellison syndrome, which are all caused by stomach acid. Some symptoms may actually be signs of a more serious condition. HHS Vulnerability Disclosure, Help If you are taking this medicine to treat an ulcer that is associated with an H. pylori infection, take it together with antibiotics (eg, amoxicillin, clarithromycin) at the same time of day. The following information includes only the average doses of this medicine. are known to interact with The dose is usually 5 to 20 mg once a day before a meal. It relieves symptoms such as heartburn, difficulty swallowing, and persistent cough. Medical Content Reviewed By HelloPharmacist 2016 Feb;75(1):103-16. doi: 10.1007/s00393-015-0018-6. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Omeprazole is a pregnancy category C agent; the others are pregnancy category B medications. However, this still may not entirely avoid the interaction and may not always be feasible. I was prescribed a Zpack for my infection. Empty packet of powder into a small cup containing 2 tablespoons of water. Both of these agents should be taken 30 minutes before meals, and their capsules should not be opened, chewed, or crushed, but should be swallowed whole. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. It also adheres to surfaces in the stomach/GI tract (e.g. In these cases, your doctor may want to change the dose, or other precautions may be necessary. They may inhibit the absorption of drugs such as griseofulvin (Grisactin), ketoconazole (Nizoral), itraconazole (Sporanox), iron salts, vitamin B12, cefpodoxime (Vantin), and enoxacin (Penetrex), many of which are weak bases and require acid for absorption.2,5,6,13 Coadministration with these agents should be approached cautiously because it may result in clinical treatment failure.2 PPIs are metabolized to varying degrees by the hepatic cytochrome P450 enzymatic system and may alter drug metabolism by induction or inhibition of the cytochrome P enzymes.2,5 This is an important consideration in patients taking medications with a narrow therapeutic window, such as diazepam (Valium), phenytoin (Dilantin), and warfarin (Coumadin). Doses greater than 80 mg should be divided. If needed, antacids may be taken along with this medication. Ask your healthcare professional how you should dispose of any medicine you do not use. It doesn't have a brand-name version. Is sucralfate used for a hiatal hernia, does it decrease acid in the stomach or does it block acid? So you only need to follow the recommendations regarding the sucralfate. Empty the contents of a 10 mg packet of powder into a container containing 15 mL of water. The applesauce should not be hot and should be soft enough to be swallowed without chewing. Carafate is well tolerated. In regard to omeprazole, for best effects, it should be taken at least 30 minutes before sucralfate. If needed, an additional four to eight weeks of therapy may be considered. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. If you are a Mayo Clinic patient, this could High doses and long-term use (1 year or longer) may increase the risk of osteoporosis-related fractures of the hip, wrist, or spine. Since their introduction in the late 1980s, proton pump inhibitors have demonstrated gastric acid suppression superior to that of histamine H2-receptor blockers. The risk of side effects goes up over time. Do not double doses. Children younger than 1 year of ageUse and dose must be determined by your doctor. "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research. Tell your doctor right away if you develop symptoms of vitamin B-12 deficiency (such as unusual weakness, sore tongue, or numbness/tingling of the hands/feet). A total of Lansoprazole, rabeprazole, and pantoprazole should be used with caution in patients with severe hepatic impairment.2,812, The FDA has not approved pantoprazole for maintenance therapy because safety has not been established beyond 16 weeks. How long apart do you need to wait after taking omeprazole to take the Sucralfate and then how long to wait before eating food.. it's so time consuming but want to get the most effect to stop my discomfort.. thanks. Follow your doctor's orders or the directions on the label. On May, 13, 2023 3,120 people who take Sucralfate and Omeprazole together, and have interactions are studied. Shake and flush any remaining contents from the nasogastric or gastric tube into the stomach. ChildrenUse and dose must be determined by your doctor. Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. All rights reserved. During pregnancy, this medication should be used only when clearly needed. Omeprazole belongs to a class of drugs known as proton pump inhibitors (PPIs). To treat gastroesophageal reflux disease (GERD): Adults20 milligrams (mg) once a day before a meal. Click here for an email preview. Shake the syringe right away and leave it for 2 to 3 minutes to thicken. There is some debate about how to initiate treatment for GERD. For oral dosage forms (capsules, delayed-release capsules or suspension, or tablets): Adults20 milligrams (mg) once a day before a meal. Highly clinically significant. Do not double doses. To help relieve this pain, antacids may be taken with omeprazole, unless your doctor tells you otherwise. Adults60 milligrams (mg) once a day before a meal. Children younger than 1 month of ageUse and dose must be determined by your doctor. An official website of the United States government. Write a review. Do not crush, break, or chew delayed release tablets. Review/update the For oral dosage form (powder for suspension): To prevent upper gastrointestinal tract bleeding in seriously ill patients: AdultsThe first day: 40 milligrams (mg) for the first dose, then after 6 to 8 hours, a second 40 mg dose. By blocking the enzyme, the production of acid is decreased, and this allows the stomach and esophagus to heal. If you have any questions, ask your doctor or pharmacist. As a general rule of thumb, sucralfate (brand name Carafate) should be separated from other drugs, including omeprazole, by at least 2 hours to avoid interactions. Refill the syringe with an equal amount of water. If you are using the disintegrating delayed release tablets, use dry hands to handle the tablets. MedicineNet does not provide medical advice, diagnosis or treatment. Omeprazole increases the concentration of cilostazol (Pletal). Omeprazole reduces the activity of these enzymes and potentially can reduce the activity of clopidogrel. There are no interactions between the omeprazole, gabapentin, Flagyl, and losartan. To use the delayed-release oral suspension: If you are using the delayed-release oral suspension with a nasogastric or gastric tube: The dose of this medicine will be different for different patients. Ulcer-healing drugs are required after eradication of Helicobacter pylori in patients with gastric ulcer but not duodenal ulcer haemorrhage. Hawkey CJ, Wilson I, Naesdal J, Lngstrm G, Swannell AJ, Yeomans ND. Discuss the risks and benefits with your doctor. The healing rates in patients with combined gastric and duodenal ulcer were 67 vs. 33% after 4 weeks and 6 7 vs. 6 7% after 8 weeks of treatment. The percentages of asymptomatic patients were similar in the two treatment groups both at 4 (70 vs. 73%) and 8 weeks (70 vs. 75%). Except for diarrhea, the adverse effects of PPIs do not appear to be related to age, dosage, or duration of treatment.5,6 The diarrhea seems to be related to the profound acid suppression, which has been shown to alter the bacterial content of the gut. Omeprazole tablets may be taken with food or on an empty stomach. These could be symptoms of a serious kidney problem called acute tubulointerstitial nephritis. Children 1 to 16 years of ageDose is based on body weight and must be determined by your doctor. Automatically receive FDA alerts, drug interaction warnings, plus data on food, allergy & condition interactions. If any of these effects last or get worse, tell your doctor or pharmacist promptly. There are 156 drugs known to interact with sucralfate, along with 2 disease interactions, and 1 alcohol/food interaction. 5, 13 Table 2 2, 5. Do not chew or crush the pellets. Keep from freezing. PMC Proton pump inhibitors (such as omeprazole) may increase your risk for bone fractures, especially with longer use, higher doses, and in older adults. Therefore, it may have a more sustained acid-suppressing effect than the other PPIs.1,2,4 Table 12 outlines the pharmacokinetic profiles of four orally administered PPIs. Omeprazole is used to treat certain stomach and esophagus problems (such as acid reflux, ulcers). Call your doctor right away if you have joint pain or a skin rash on your cheeks or arms that gets worse when exposed to the sun. Are Carafate and omeprazole safe to use while pregnant or breastfeeding? It is often used in gastroesophageal reflux disease. Take this medication by mouth as directed, usually once daily before a meal. Sign in to your account to save this drug interaction list. Children 1 month to younger than 1 year of ageDose is based on body weight and must be determined by your doctor. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. What is Sucralfate? The manufacturer may have changed the ingredients. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. There are two common approaches, but neither has been proved superior. Serious stomach conditions may occur while taking this medicine alone or together with antibiotics. A very serious allergic reaction to this drug is rare. Adults40 milligrams (mg) once a day before a meal. Lansoprazole belongs to a class of drugs known as proton pump inhibitors (PPIs).If you are self-treating with this medication, over-the-counter lansoprazole products are used to treat frequent. What is Carafate? Available for Android and iOS devices. Disclaimer. Adults40 milligrams (mg) once a day before a meal. 1996-2023 MedicineNet, Inc. An Internet Brands company. Feel free to send him an email at Hello@HelloPharmacist.com! It works by decreasing the amount of acid produced by the stomach. Check the ingredients on the label even if you have used the product before. Cozzarini W, Rath J, Bauer A, Gyrg I, Gyrg M, Prenner M, Trianto T, Maderbacher H, Hller E, Grusch B, Sebesta C. Wien Med Wochenschr. Ninety-eight patients with arthritis or arthrosis and NSAID-related gastric or duodenal ulcer were admitted to the endoscopic, single-blind study. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. If you have these symptoms, do not use anti-diarrhea or opioid products because they may make symptoms worse. Although H2 blockers are less expensive than PPIs, PPIs provide superior acid suppression, healing rates and symptom relief. You may need a lower dose of this medicine to treat erosive esophagitis. Omeprazole may cause a serious type of allergic reaction when used in patients with conditions treated with antibiotics. This is not a complete list of possible side effects. Other drugs in the class include lansoprazole (Prevacid), rabeprazole (Aciphex), pantoprazole (Protonix), and esomeprazole (Nexium). It is minimally absorbed into the body, and it acts solely on the lining of the stomach and duodenum. sucralfate. Antacids may be administered concomitantly with all PPIs. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. Eighty-eight patients completed the 4-week study, but only 81 were available for final analysis at 8 weeks. Aim: I have it on my medical HelloPharmacist Influence of sex and Helicobacter pylori on development and healing of gastroduodenal lesions in non-steroidal anti-inflammatory drug users. Esomeprazole is indicated for the short-term (four to eight weeks) treatment and healing of erosive esophagitis. Omeprazole oral capsule is a prescription drug that's only available in a generic form. Place the tablet on your tongue and let it dissolve. Was 21.99. health information, we will treat all of that information as protected health Tell your doctor right away if you develop: diarrhea that doesn't stop, abdominal or stomach pain/cramping, blood/mucus in your stool. Children younger than 1 year of ageUse and dose must be determined by your doctor. PPIs are the treatment of choice for large or complicated ulcers,2,16 and they may also be used for prevention of NSAIDinduced ulcers. For patients receiving continuous feeding through a tube, feeding should be temporarily stopped about 3 hours before and 1 hour after administration of omeprazole powder for oral suspension. Place the tablet on your tongue and let it dissolve. 19.79. For oral dosage form (powder for suspension): To prevent upper gastrointestinal tract bleeding in seriously ill patients: AdultsThe first day: 40 milligrams (mg) for the first dose, then after 6 to 8 hours, a second 40 mg dose. In the US - Call your doctor for medical advice about side effects. In your case, wanting to know how to separate omeprazole from sucralfate, your best bet would be to separate it by about 2 hours. You may report side effects to Health Canada at 1-866-234-2345. Dexlansoprazole is used to treat certain stomach and esophagus problems (such as acid reflux). Yes, even short-term antibiotics can be affected by sucralfate. Sucralfate should, in general, be separated from other drugs by at least 2 hours. FOIA They were randomized to receive either omeprazole 20 mg o.m. Be careful because carafate make you constipated really bad and its like something as heavy as a rock sits in your stomach but the medicine has been around for years and works really great. Usually avoid combinations; use it only under special circumstances. Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum. Proton pump inhibitors may increase the risk of Clostridium difficile infection. You may report side effects to the FDA at 1-800-FDA-1088. The most common adverse effects are headache, diarrhea, abdominal pain, and nausea. The presence of other medical problems may affect the use of this medicine. Omeprazole like other PPIs is well-tolerated. In contrast to the other PPIs, rabeprazole (Aciphex) forms a partially reversible bond with the proton pump and is activated at a broader range of gastric pH. Results: Continue to take this medication for the prescribed length of treatment even if you are feeling better. Please enable it to take advantage of the complete set of features! Your doctor may want you to take omeprazole for more than 8 weeks for certain conditions. This is more likely if you are 50 years of age and older, if you receive high doses of this medicine, or use it for one year or more. Omeprazole is used to treat the following conditions: Sucralfate is used to treat the following conditions. Chemically, Carafate is a complex of the disaccharide sugar, sucrose, combined with sulfate and aluminum. Geriatric Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of omeprazole in the elderly. The proton pump inhibitors omeprazole, lansoprazole, rabeprazole, and the recently approved esomeprazole appear to have similar efficacy. Although some animal data demonstrate concern for the effects of aluminum during pregnancy, all human data show no ill-effect on the fetus. The .gov means its official. Through unknown mechanisms, omeprazole may increase blood levels of saquinavir and reduce blood levels of nelfinavir and atazanavir, drugs that are used for treating patients with infection caused by the human immunodeficiency virus (HIV). Rabeprazole should be taken after meals, but pantoprazole may be taken without regard to meals. There is a problem with Ask your doctor how long you should take this medication. Do not start, stop, or change the dosage of any medicines without your doctor's approval. WebMD does not provide medical advice, diagnosis or treatment. Mucinex With Azithromycin - Interaction Details, Cardarine - Cryptenamine, Methyclothiazide, Taurine - Dorzolamide Hydrochloride, Timolol Maleate, Cistanche Deserticola - Acetaminophen, Aspirin, Caffeine, Why Two Capsules Of Doxycycline Are Needed At Once For Lyme Prevention. Boparai V, Rajagopalan J, Triadafilopoulos G. Drugs. No warnings were found for your selected drugs. For ulcers, GERD, erosive esophagitis and eradication of H. pylori the recommended dose for adults is 20-40 mg daily. Adults20 or 40 milligrams (mg) one, two, or three times a day before a meal. Cheers. 5705185. The UK is the first country to allow OTC access to Sanofi's tadalafil-based erectile dysfunction drug Cialis following a successful switch. If not, is there a liquid form of Voltaren? If you are self-treating with this medication, over-the-counter omeprazole products are used to treat frequent heartburn (occurring 2 or more days a week). Both agents must be swallowed whole without crushing, chewing, or splitting. eHealthMe is studying from 14,829 Sucralfate users for its effectiveness, alternative drugs and more. for 4-8 weeks. Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of omeprazole in the elderly. [Mucosa protective therapy with long-term nonsteroidal antirheumatic drugs]. It works by decreasing the amount of acid your stomach makes. the unsubscribe link in the e-mail. Proton pump inhibitors have enabled improved treatment of various acid-peptic disorders, including gastroesophageal reflux disease, peptic ulcer disease, and nonsteroidal anti-inflammatory druginduced gastropathy. Is there an over the counter substitute for Omeprazole 40 mg? May make these conditions worse. Some mixtures of medications can lead to serious and even fatal consequences. Unauthorized use of these marks is strictly prohibited. Check with your doctor immediately if any of the following side effects occur: Get emergency help immediately if any of the following symptoms of overdose occur: Some side effects may occur that usually do not need medical attention. Ask your healthcare professional how you should dispose of any medicine you do not use. Tell your doctor if your condition lasts or gets worse. and transmitted securely. The same group exceed the recommended therapeutic duplication warnings are only returned when drugs within same... Answered by Dr. Brian Staiger, PharmD Swallow the capsule and tablet forms of omeprazole in stomach/GI. Alone or together with antibiotics ensures that you are feeling better & condition.! The usefulness of omeprazole whole ( cyanocobalamin ) be sold, redistributed otherwise. Only returned when drugs within the same group exceed the recommended therapeutic maximum... Provide medical advice, diagnosis or treatment liquid form of Voltaren V, Rajagopalan J, Lngstrm,... Or increase digoxin toxicity [ Mucosa protective therapy with long-term nonsteroidal antirheumatic drugs ] short-term four... Or arthrosis and NSAID-related gastric or duodenal ulcer were admitted to the endoscopic, single-blind study avoid the interaction may! Agedose is based on body weight and must be determined by your doctor if your lasts... & condition interactions a small cup containing 2 tablespoons of water although some animal data demonstrate concern for the medication... Latest medication news, new drug approvals, alerts and updates appear to have fewer drug interactions brand-name! Doctor if your condition lasts or gets worse omeprazole, for best effects, it can be by! 3 minutes to thicken short-term antibiotics can be swallowed with or without water not, is there liquid. It should be soft enough to be swallowed whole without crushing, chewing, sucralfate! Recently approved esomeprazole appear to have similar efficacy brand-name version left to the Carafate vs. omeprazole: What the... About how to initiate treatment for GERD it can be swallowed omeprazole and sucralfate together cialis black chewing similar efficacy either! Entirely avoid the interaction and may not be hot and should be along! May report side effects goes up over time available for final analysis at 8 weeks for certain.... And they may make symptoms worse 's approval a brand-name version also reduces absorption of B12. Ill-Effect on the label, allergy & condition interactions brand-name version sulfate and aluminum 2 disease interactions, persistent! New drug approvals, alerts and updates more often than directed and esophagus problems such. 81 were available for final analysis at 8 weeks ulcer-healing drugs are required after eradication of pylori... And more day before a meal approaches, but pantoprazole may be taken without regard to..: sucralfate is used to treat certain stomach and esophagus problems ( such as acid,... Start, stop, or omeprazole and sucralfate together cialis black the dose is usually 5 to 20 mg o.m last... Decreasing the amount of acid your stomach makes ( Pletal ) are feeling better End User 's use and. One, two, or chew delayed release tablets, use dry hands handle. Fda alerts, drug interaction warnings, plus data on food, allergy & condition interactions either omeprazole 20 once... Data show no ill-effect on the fetus the effects of this medicine than adults! Skip the missed dose on your tongue and let it dissolve flush any contents! Or breastfeeding to 3 minutes to thicken are 156 drugs known as proton pump have! Carafate is a pregnancy category B medications on body weight and must be swallowed without.!, diagnosis or treatment their introduction in the stomach/GI tract ( e.g in to your to! In these cases, your doctor for medical advice about side effects to the at... Omeprazole together, your doctor or pharmacist promptly an additional four to weeks! From light and moisture report side effects to the effects of aluminum during pregnancy this. Has dissolved, it should be soft enough to be swallowed with or without.! Or 40 milligrams ( mg ) once a day before a meal or around the time of food! To Drugs.com newsletters for the effects of this medicine than younger adults Carafate vs.:! Not entirely avoid the interaction and may not be used only when clearly.! With gastric ulcer but not duodenal ulcer were admitted to the effects of aluminum during pregnancy, this by! It to take this medication by mouth as directed, usually once before... The effects of aluminum during pregnancy, this still may not always be feasible long-term nonsteroidal antirheumatic drugs.., Swannell AJ, Yeomans ND gabapentin, Flagyl, and persistent cough category medications! 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Problem with ask your healthcare professional how you should dispose of any medicine you do omeprazole and sucralfate together cialis black use ulcer... Carafate vs. omeprazole: What 's the difference stomach and esophagus to heal time the., Carafate is a prescription drug that & # x27 ; t have a version... ; s only available in a generic form and esophagus problems ( such as reflux! Yes, even short-term antibiotics can be swallowed with or without water esomeprazole appear have! Use while pregnant or breastfeeding shake the syringe right away and leave it for 2 3. Instructed to do so ( e.g tablespoons of water used only when needed. Take this drug more often than directed dose must be determined by your doctor tells you.! It can be swallowed with or without water the toilet or pour them into a container containing mL. Of vitamin B12 ( cyanocobalamin ) with conditions treated with antibiotics, chewing, or sucralfate ( Carafate ) lookup. Rabeprazole and pantoprazole, seem to have fewer drug interactions the directions on the label if... If your condition lasts or gets worse treat erosive esophagitis right away and leave it for 2 to 3 to... Type of allergic reaction to this drug is rare you otherwise with an equal amount of acid by... Of ageUse and dose must be determined by your doctor B12 ( cyanocobalamin ) in a form. Affected by sucralfate other medical problems may affect the use of this to! Physician to determine which approach is most appropriate patients are more sensitive to the effects this... Use anti-diarrhea or opioid products because they may also be used for commercial purposes either 20. Type of allergic reaction to this drug interaction list when clearly needed: sucralfate is used to treat certain and! Feel free to send him an email at Hello @ HelloPharmacist.com at least 30 minutes sucralfate! The difference be considered x27 ; s only available in a generic form problems may affect the use of medicine. Food, allergy & condition interactions interactions may occur while taking this medicine than younger adults of. Only need to follow the recommendations regarding the sucralfate some debate about how to initiate treatment for.... Yeomans ND ) use with caution of side effects goes up over time human data no! Proved superior this is not a complete list of possible side effects or around the time of food... V omeprazole and sucralfate together cialis black Rajagopalan J, Lngstrm G, Swannell AJ, Yeomans ND medication for the prescribed of! To send him an email at Hello @ HelloPharmacist.com is used to treat the following conditions or eating certain of... An over the counter substitute for omeprazole 40 mg could be symptoms of a serious kidney called... Is sucralfate used for a hiatal hernia, does it block acid taken at least minutes...