WARNINGS Orally and parenterally administered clindamycin has been associated with severe colitis which may result in patient death. Monitor the breast-fed infant for possible adverse effects on the gastrointestinal flora, such as diarrhea, candidiasis (thrush, diaper rash) or rarely, blood in the stool indicating possible antibiotic-associated colitis. We anticipate reposting the images once we are able identify and filter out images that do not match the information provided in the drug labels. Welcome to our complete breakdown of the best 3 Greenstone Brand Clindamycin Phosphate Topical Lotion 1% dupes and alternatives . FREE delivery Insurance price also available Prescription Required DailyMed will deliver notification of updates and additions to Drug Label information currently shown on this site through its RSS feed. They both do not contain any harsh alcohols, common allergens, fragrances, oils or silicones. It is not known whether clindamycin is excreted in human milk following use of clindamycin phosphate. The gel contains allantoin, carbomer 974P, methylparaben, polyethylene glycol 400, propylene glycol, sodium hydroxide, and purified water. Subjects with excessive facial hair such as beards, sideburns, moustaches, etc. To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor. A 1% clindamycin phosphate gel similar to clindamycin phosphate caused a statistically significant shortening of the median time to tumor onset in a study in hairless mice in which tumors were induced by exposure to simulated sunlight. It may be used alone or with one or more other medicines that are used on the skin or taken by mouth for acne. Build your routine, like + dislike ingredients, and more with your free account. The cost for clindamycin topical topical gel 1% is around $30 for a supply of 30 grams, depending on the pharmacy you visit. In 18 clinical studies of various formulations of clindamycin phosphate using placebo vehicle and/or active comparator drugs as controls, patients experienced a number of treatment emergent adverse dermatologic events [seetablebelow]. Updated Brand names for clindamycin topical include Clindagel, Cleocin T, Clindesse, and Cleocin Vaginal. You can use our Dupe Finder to search for them!. They've got a total of 3 ingredients in common. Free of the top common allergy causing ingredients (fragrances, preservatives, topical antibiotics, sunscreens and metals), surfactants (cocamidopropyl betaine) and harmful hormone-altering chemicals and ingredients. Vancomycin has been found to be effective in the treatment of antibiotic-associated pseudomembranous colitis produced by Clostridium difficile. No significant increase in tumors was noted in the treated animals. Free of Methylisothiazolinone, Methylchloroisothiazolinone and related kathon-like ingredients. (current), clindamycin (as clindamycin phosphate) 1 % Topical Gel. Male or non-pregnant, non-lactating female, 12 and 40 years of age with a clinical diagnosis of acne vulgaris. If you are a consumer or patient please visit Product Information Customer Reviews Product Summary This product requires a valid prescription for shipment, please note that HealthWarehouse.com may not accept prescriptions faxed or emailed by patients. Cases of diarrhea, bloody diarrhea, and colitis (including pseudomembranous colitis) have been reported as adverse reactions in patients treated with oral and parenteral formulations of clindamycin and rarely with topical clindamycin (see WARNINGS). If both a resin and vancomycin are to be administered concurrently, it may be advisable to separate the time of administration of each drug. To report SUSPECTED ADVERSE REACTIONS, contact Solaris Pharma Corporation at 1-833-919-0527 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch. Why Should I Register and Submit Results? Clindamycin phosphate gel, 1% is indicated for topical application in the treatment of acne vulgaris. Events, (What check out our CLINDAMYCIN PHOSPHATE GEL USP 1% 30 G: 1.00 TU: TOPICAL, GEL: Prescribing Information: DERMATOLOGICALS: CLEOCIN T: 00168020260: CLINDAMYCIN PHOSPHATE GEL USP 1% 60 G: 1.00 TU: TOPICAL, GEL: Prescribing Information: DERMATOLOGICALS: CLEOCIN T: 00168020360: CLINDAMYCIN PHOSPHATE LOTION USP 1% 60ML: 1.00 BT: TOPICAL, LOTION: Prescribing . Manufactured for: These products are both facial treatments Cross-resistance between clindamycin and lincomycin is complete. Files, Presentations RX347237, 347237, NDC No. Myroxylon pereirae (STRICT Avoidance; Products will not contain Benzyl Alcohol, Benzoic Acid, Sodium Benzoate, Cinnamates, Octocrylene), Find irritant free beauty, skincare & household products that are free of ingredients like retinol/retinal, glycolic acid, alpha hydroxy acids, benzoyl peroxide and peeling or resurfacing agents that can make your skin sensitive. It More reviews, photos and discussions for Unlisted Brand, Advanced Night Repair Synchronized Recovery Complex [REFORMULATED], Perfectionist [CP+R] Wrinkle Lifting/Firming Serum. (Clinical Trial), A Multi-Center, Double-Blind, Randomized, Vehicle-Controlled, Parallel-Group Study Comparing Clindamycin 1% Gel To Clindamycin 1% Gel (Greenstone LLC) and Both Active Treatments to Vehicle Control in the Treatment of Acne Vulgaris, Experimental: Clindamycin 1% gel (Akorn Pharmaceuticals), Active Comparator: Clindamycin 1% gel (Greenstone LLC), Sherman Oaks, California, United States, 91403, High Point, North Carolina, United States, 27262. Therefore, it should be used with caution in patients receiving such agents. Clindamycin phosphate gel, 1% is contraindicated in individuals with a history of hypersensitivity to preparations containing clindamycin or lincomycin, a history of regional enteritis or ulcerative colitis, or a history of antibiotic-associated colitis. You can use our Dupe Finder to search for them! They both contain sulfates. Free of allergy causing lanolins, esters, waxes and other wool related ingredients. Solaris Pharma Corporation Bridgewater, NJ 08807, Report Adverse CLINICAL PHARMACOLOGY Mechanism of Action - The mechanism of action of clindamycin in treating acne vulgaris is unknown. Recommended Products. Information provided by (Responsible Party): This is a randomized, double-blind, multiple-site, placebo-controlled, parallel-group study, designed to compare the efficacy and safety of generic Clindamycin 1% gel (Akorn), and the marketed product Clindamycin 1% gel (Greenstone LLC) in the treatment of acne vulgaris. Sold by marush2021. Not for Injection WARNING There was no signal for contact sensitization in the clinical trials under normal use conditions. See Ratings. Dr. Jennifer Haley answered I have dry skin that is sensitive and a lot of products would burn my skin or make the acne worse. Clindamycin is bacteriostatic. Clinical Trials, Please remove one or more studies before adding more. Free of fragrances and the most common allergy causing botanicals such as balsam of peru, cinnamic aldehyde, propolis (bee glue) and many more. Because animal reproduction studies are not always predictive of human response, this drug should be used during pregnancy only if clearly needed. It's not as effective as I wished, but I didn't have major hopes anyway. Free of ADDED gluten and other wheat-related ingredients, including barley, rye and oat. Endoscopic examination may reveal pseudomembranous colitis. people understand The mechanism of action of clindamycin in treating acne vulgaris is unknown. Clindamycin phosphate is a water soluble ester of the semi-synthetic antibiotic produced by a 7(S)-chloro-substitution of the 7(R)-hydroxyl group of the parent antibiotic lincomycin. 203,253 Resistance to clindamycin is most often caused by modification of specific bases of the 23S ribosomal RNA. Clindamycin topical may also be used for purposes not listed in this medication guide. My lips, chin, jaw and throat swelled. In vitro studies indicated that clindamycin inhibited all tested Propionibacterium acnes cultures at a minimum inhibitory concentration (MIC) of 0.4 mcg/mL. this version. Apply a thin film of clindamycin phosphate gel USP, 1% once daily to the skin where acne lesions appear. Due to inconsistencies between the drug labels on DailyMed and the pill images provided by RxImage, we no longer display the RxImage pill images associated with drug labels. Fast delivery, full service customer support. Free of added nickel and cobalt as listed on the product label. I went to a new Youve got to give this medication time to work. 1% clindamycin topical topical gel. Clindamycin phosphate gel USP, 1%, a topical antibiotic, contains clindamycin phosphate, at a concentration equivalent to 10 mg clindamycin per gram in a gel vehicle consisting of carbomer 981, methylparaben, polyethylene glycol 400, propylene glycol, purified water, and sodium hydroxide. Because the binding sites for these antibacterial drugs overlap, cross resistance is sometimes observed among lincosamides, macrolides and streptogramin B. Macrolide-inducible resistance to clindamycin occurs in some isolates of macrolide-resistant bacteria. Events, General: Clindamycin phosphate should be prescribed with caution in atopic individuals. Leave . : 59762-3743-02, 59762-743-02, 5976274302, 59762374302, 3743-02, 374302 UPC No. Answered Jun 24, 2021 Thank A 31-year-old member asked: Is it okay to use a bior strip on my nose while using clindamycin phosphate topical gel? Find dye free beauty, skincare & household products that are free of colorants & dyes that can cause skin sensitivities. This is a decision you and your doctor will make. Orally and parenterally administered clindamycin has been associated with severe colitis, which may result in patient death. . Read more. clindamycin phosphate topical gel and clindamycin phosphate topical lotion are indicated in the treatment of acne vulgaris. Solaris Pharma Corporation. These studies revealed no evidence of fetal harm. that would interfere with the diagnosis or assessment of acne. I then washed my face again, and the rash subsided. facial treatment that contains 10 ingredients. guide. Free of coconut and related allergy causing coconut derivatives; however, highly processed ingredients derived from coconut (e.g., glycerin or tocopherol) will not be excluded by SkinSAFE. . Symptoms of ED include. Solution Lotion Pad Gel/Jelly Before Using In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. Free of formaldehyde and the most common allergy causing preservatives such as benzalkonium chloride, formaldehyde, benzophenone, methyldibromo glutaronitrile, MCI/MI and others. Subject has more than 2 facial nodular lesions; any nodules present will be documented but not included in the inflammatory lesion count for analysis. ED is often a symptom of another health problem or health-related factor. Therefore, it should be used with caution in patients receiving such agents. CLINDAMYCIN PHOSPHATE- clindamycin phosphategel Clindamycin phosphate gel, 1% is indicated in the treatment of acne vulgaris. The alcohol in it may irritate freshly washed or shaved skin. Clindamycin phosphate gel USP, 1%, a topical antibiotic, contains clindamycin phosphate, at a concentration equivalent to 10 mg clindamycin per gram in a gel vehicle consisting of carbomer 981, methylparaben, polyethylene glycol 400, propylene glycol, purified water, and sodium hydroxide. FDA Safety Recalls, It is not known whether clindamycin is excreted in breast milk following use of clindamycin phosphate. I BE PATIENT! Welcome to our complete breakdown of the best Clindamycin belongs to the family of medicines called antibiotics. Free of the most common fragrances, preservatives, soap and glue ingredients that cause eyelid rashes (Its Top Free plus no gold, thimerosal, soaps related to cocamidopropyl betaine, or glues/adhesives like shellac or acrylate monomers; also free of Meibomian gland toxic ingredients including phenoxyethanol, parabens, and chlorphenesin). Citations, Report Adverse Have facial acne with: 20 facial inflammatory lesions (papules and pustules) and 25 non-inflammatory lesions (open and closed comedones), and 2 nodulocystic lesions (nodules and cysts) and have an IGA score of 2, 3 or 4. I just have a question so First I wash my face then I put the stuff on . but do I wash it off with water , or do I leave it on the whole day ?? Products - GREENSTONE 2020 Viatris Inc. . The colitis is usually characterized by severe persistent diarrhea and severe abdominal cramps and may be associated with the passage of blood and mucus. The structural formula is represented below: Clindamycin phosphate vaginal cream 2%, is a semi-solid, white cream, which contains 2% clindamycin phosphate, USP, at a concentration equivalent to 20 mg clindamycin per gram. 3-59762-37432-5, 359762-374325, 359762374325, Category:RX, Generic Drug Classification: Anti-Infectives Lincomycin Derivatives Drug Class: Drug Class: 84040400 Antibacterials (Skin Mucous Membrane) Brand . 3 Greenstone Brand Clindamycin Phosphate Topical Lotion 1% dupes and alternatives For patients using the topical foam form of clindamycin: After washing or shaving, it is best to wait 30 minutes before applying this medicine. Pharmacokinetics: In an open-label, parallel group study of 24 patients with acne vulgaris, once-daily topical administration of approximately 3 to 12 grams/day of clindamycin phosphate for 5 days resulted in peak plasma clindamycin concentrations that were less than 5.5 ng/mL. Listing a study does not mean it has been evaluated by the U.S. Federal Government. It has a molecular weight of 504.96, and the molecular formula is C 18 H 34 ClN 2 O 8 PS. Shop Women's Greenstone Brand White Green Size 60gram Acne & Blemish at a discounted price at Poshmark. This medicine contains alcohol and is flammable. being able to get an erection sometimes, but not every time you want to have sex. Read our, ClinicalTrials.gov Identifier: NCT03522441, Interventional from $29.90 for 30 grams. Chemically, clindamycin phosphate is a water-soluble ester of the semi-synthetic antibiotic produced by a 7 (S)-chlorosubstitution of the 7 (R)-hydroxyl group of the parent antibiotic, lincomycin, and has the structural formula represented below: The chemical name for clindamycin phosphate is methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl-trans-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-L-threo-a-D-galacto-octopyranoside 2-(dihydrogen phosphate). Safety and effectiveness in pediatric patients under the age of 12 have not been established. This is a randomized, double-blind, multiple-site, placebo-controlled, parallel-group study, designed to compare the efficacy and safety of generic Clindamycin 1% gel (Akorn), and the marketed product Clindamycin 1% gel (Greenstone LLC) in the treatment of acne vulgaris. PubMed, Large bowel endoscopy should be considered to establish a definitive diagnosis in cases of severe diarrhea. In view of the potential for diarrhea, bloody diarrhea, and pseudomembranous colitis, the physician should consider whether other agents are more appropriate. (See CONTRAINDICATIONS, WARNINGS, and ADVERSE REACTIONS.). Clindamycin Phosphate Topical Gel 1%, 60g, Greenstone (RX) 3 favorites. Store at 20 to 25C (68 to 77F); excursions permitted between 15 to 30C (59 to 86F) [see USP Controlled Room Temperature]. Studies indicate a toxin(s) produced by Clostridia is one primary cause of antibiotic-associated colitis. I had a severe reaction to this topical gel. Topically applied clindamycin phosphate can be absorbed in sufficient amounts to produce systemic effects (see WARNINGS). being unable to get an erection at any time. Following multiple applications of clindamycin phosphate less than 0.04% of the total dose was excreted in the urine. Labels, All Index It can also be used to treat acne, and some cases of methicillin-resistant Staphylococcus aureus (MRSA). To apply this medicine: Endoscopic examination may reveal pseudomembranous colitis. Flag. 73473-300-30, For a rat, this dose is 84- fold higher and for a mouse, 42-fold higher than the anticipated human dose of clindamycin phosphate from clindamycin phosphatebased on a mg/m2 comparison. However, orally and parentally administered clindamycin has been reported to appear in breast milk. The developmental and health benefits of breastfeeding should be considered along with the mother's clinical need for clindamycin and any potential adverse effects on the breast-fed child from clindamycin or from the underlying maternal condition. The colitis is usually characterized by severe persistent diarrhea and severe abdominal cramps and may be associated with the passage of blood and mucus. I then used clindamycin phosphate 1% LOTION, and the ac . Although clindamycin phosphate is inactive in vitro, rapid in vivo hydrolysis converts this compound to the antibacterially active clindamycin. About this product: Chemically, clindamycin phosphate is a water-soluble . Stool culture for Clostridium difficile and stool assay for C. difficile toxin may be helpful diagnostically. with the ingredients and function of 59762-3743-01: Product Dating: McKesson Acceptable Dating: we will ship >= 90 days: Strength: 1%: Type: Topical: UNSPSC Code: 51283006: Volume: 30 Gram: More Information. Endoscopic examination may reveal pseudomembranous colitis. Get Label RSS Feed, Clindamycin is active in vitro against most isolates of Propionibacterium acnes; however, the clinical significance is unknown. PRESCRIPTION REQUIRED IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. Genotoxicity tests performed included a rat micronucleus test and an Ames Salmonella reversion test. RxNorm, Cases of diarrhea, bloody diarrhea and colitis (including pseudomembranous colitis) have been reported as adverse reactions in patients treated with oral and parenteral formulations of clindamycin and rarely with topical clindamycin (see WARNINGS). Biochemical Data Summary. Use of the topical formulation of clindamycin results in absorption of the antibiotic from the skin surface. View NDC Code(s)NEW! My acne was in no way severe, but definitely got out of hand when my proactiv stopped working for me. SDS . Find sodium lauryl sulfate (SLS) free beauty, skincare and household products. In view of the potential for diarrhea, bloody diarrhea and pseudomembranous colitis, the physician should consider whether other agents are more appropriate (see CONTRAINDICATIONS,WARNINGS and ADVERSE REACTIONS). 73473-300-60. Solaris Pharma Corporation Bridgewater, NJ 08807,USA, Set id: fde07866-b012-47ad-932e-b76f141f86ee, 75 mL in 1 BOTTLE; Type 0: Not a Combination Product. We don't currently have data on the retail price of Greenstone Brand Clindamycin Phosphate Topical Lotion 1%. The highest dose used in the rat and mouse teratogenicity studies was equivalent to a clindamycin phosphate dose of 432 mg/kg. CLINDAMYCIN PHOSPHATE TOPICAL GEL: Cleocin Prescribing Information: Prescribing Information: CLINDAMYCIN PHOSPHATE TOPICAL LOTION: Cleocin Prescribing Information: Prescribing Information: CLINDAMYCIN PHOSPHATE TOPICAL SOLUTION, USP: Cleocin Prescribing Information: Prescribing Information: CLINDAMYCIN PHOSPHATE VAGINAL CREAM, USP . Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03522441, The new site is coming soon - go to the modernized. Diarrhea, colitis, and pseudomembranous colitis have been observed to begin up to several weeks following cessation of oral and parenteral therapy with clindamycin. At Poshmark this medication guide of the topical formulation of clindamycin phosphate,. 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Facial hair such as beards, sideburns, moustaches, etc every time you want have. Will make is often a symptom of another health problem or health-related factor of,...