Beta-blocker medications (including metoprolol, propranolol, glaucoma eye drops such as timolol) may prevent the fast/pounding heartbeat you would usually feel when your blood sugar falls too low (hypoglycemia). Glyburide may interact with other medications, Important considerations for taking glyburide, dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=5d0e406f-285d-4716-8971-82f665345517, dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=ca26071d-1ff4-4000-8104-17f211cc6b71, dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=172ff8f1-586d-4df1-a4ef-13185d1b40dd, dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=a7fce80a-2f13-43cc-8e1c-561f7d3ec3d5, A Guide to Living with Diabetes and High Cholesterol, This Is the Best Time of Day to Exercise for People with Type 2 Diabetes, Continuous Glucose Monitors (CGMs) May Diagnose Prediabetes Earlier Than Blood Sugar Tests, Top Natural Ways to Improve Your Insulin Sensitivity, The Benefits and Risks of Avocados for People with Diabetes, Insulin Injection Sites: Where and How to Inject. This can be harmful or prevent the drug from working well. Do not share this medication with others. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. Do not double the dose to catch up. Its also available in a generic form. Glyburide is usually taken with breakfast or the first main meal of the day. Portions of this document last updated: May 01, 2023, Original article: https://www.mayoclinic.org/drugs-supplements/glyburide-and-metformin-oral-route/side-effects/drg-20061991. Check with your physician for additional information about side effects. For women who are breastfeeding: Glyburide hasnt been shown to pass through breast milk. If you are already taking another diabetes drug (such as chlorpropamide), follow your doctor's directions carefully for stopping the old drug and starting glyburide. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. Appropriate studies have not been performed on the relationship of age to the effects of glyburide and metformin combination in the pediatric population. Read and follow the instructions carefully. Write a review. Visit the RxList Drug Interaction Checker for any drug interactions. If you don't have these reliable forms of glucose, rapidly raise your blood sugar by eating a quick source of sugar such as table sugar, honey, or candy, or drink fruit juice or non-diet soda. Both of these medications work by helping to restore your body's proper response to the insulin you naturally produce.Controlling high blood sugar helps prevent kidney damage, blindness, nerve. This information does not contain all possible interactions or adverse effects. The information provided here is for informational purposes only. A glyburide overdose can cause life-threatening hypoglycemia. Under certain conditions, too much metformin can cause lactic acidosis. Glyburide oral tablet is used for long-term treatment. Are avocados a safe and healthy food for people with type 2 diabetes? Taking aspirin or other NSAIDs with glyburide can cause symptoms of low blood sugar. This information does not contain all possible interactions or adverse effects. Before having surgery or any X-ray/scanning procedure using iodinated contrast, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). All sulfonylureas are capable of producing severe hypoglycemia. Blood tests may be needed to check for unwanted effects. Glyburide is a second generation sulfonylurea used to treat patients with diabetes mellitus type II. This is a decision you and your doctor will make. Call 911 if your symptoms feel life-threatening or if you think youre having a medical emergency. Taking antacids with glyburide may cause increased effects of glyburide in your body. If you have any symptoms of lactic acidosis, get emergency medical help right away. Metformin reduces the absorption of sugar from the stomach, reduces the release of stored sugar from the liver, and helps your body use sugar better. Things to remember when you fill your prescription. In type 2 diabetes, your body does not work properly to store excess sugar and the sugar remains in your bloodstream. What Are the Best PsA Treatments for You? Glyburide belongs to the class of drugs known as sulfonylureas. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Glyburide is used to treat type 2 diabetes. Test your blood sugar 15 minutes after you treat the low sugar reaction. Taking clarithromycin with glyburide can increase the amount of glyburide in your body. Helps you get and maintain an erection when you need it. Do not start, stop, or change the dosage of any medicines without your doctor's approval. May make these conditions worse. Brand names: DiaBeta, Glynase PresTab, Micronase Advertising revenue supports our not-for-profit mission. Generic Name Glyburide DrugBank Accession Number DB01016 Background. Glyburide is available as the brand-name drugs Diabeta and Glynase PresTabs. Pregnancy may cause or worsen diabetes. Tell your doctor right away if you get sunburned or have skin blisters/redness. Initial daily glyburide dose: 5 mg (conventional formulation) and increase in increments of 1.25 to 2.5 mg every 2 to 10 days OR 3 mg (micronized formulation) and increase in increments of 0.75 to 1.5 mg every 2 to 10 days. Moderately clinically significant. Carry hard candy or glucose tablets with you in case you have low blood sugar. To help you remember, take it at the same time(s) each day. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. Use the medicine exactly as directed. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. Copyright 2023 by RxList Inc. An Internet Brands company. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. If you become pregnant while taking this drug, call your doctor right away. Any other condition that causes low blood sugarPatients with these conditions may be more likely to develop low blood sugar while taking glyburide and metformin combination. TravelKeep your recent prescription and your medical history with you. Use this medication regularly to get the most benefit from it. Mayo Clinic is a nonprofit organization and proceeds from Web advertising help support our mission. For mild hypoglycemia (5570 mg/dL), treatment is 1520 grams of glucose (a type of sugar). Talk to your pharmacist for more details. -Administer with breakfast or the first main meal of the day Store at room temperature away from moisture and heat. Drug interactions may change how your medications work or increase your risk for serious side effects. Before taking glyburide, tell your doctor if you are allergic to sulfa drugs, if you have been using insulin or chlorpropamide (Diabinese), or if you have hemolytic anemia (a lack of red blood cells), an enzyme deficiency (G6PD), a nerve disorder, liver disease, or kidney disease. If any of these effects last or get worse, tell your doctor or pharmacist promptly. Patients with stress due to infection, fever, Caution in hepatic or renal insufficiency, Administration of oral hypoglycemic drugs has been reported to be associated with increased, There are no clinical studies establishing conclusive evidence of. Most frequently checked interactions View interaction reports for glyburide and the medicines listed below. Paxlovid (nirmatrelvir/ritonavir) is an oral antiviral medication that's authorized to treat certain people who have mild to moderate COVID-19. Make your tax-deductible gift and be a part of the cutting-edge research and care that's changing medicine. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Talk to your doctor about the best way to treat low blood sugar. Your doctor will write the number of refills authorized on your prescription. Your child will be monitored for signs of low blood sugar. -Dose titration: Increase in increments of no more than 2.5 mg at weekly intervals based upon blood glucose response Indications. You may report side effects to Health Canada at 1-866-234-2345. Rarely, alcohol can interact with glyburide and cause a serious reaction (disulfiram-like reaction) with symptoms such as facial flushing, nausea, vomiting, dizziness, or stomach pain. RxList does not provide medical advice, diagnosis or treatment. Glyburide, also referred to as glibenclamide, is a second-generation sulfonylurea approved by the Food and Drug Administration (FDA) for the treatment of type 2 diabetes mellitus. If youre taking metoclopramide with glyburide, your dose of glyburide may need to be changed. [1] use a blood glucose monitor to test your blood sugar regularly, recognize the symptoms of high and low blood sugar, lancets to prick your finger to test your blood sugar, blood glucose monitor to test you blood sugar at home, glycosylated hemoglobin (A1C) levels (your doctor will do a test to measure your blood sugar control over the last 23 months). Call your doctor right away if you have serious side effects. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor right away if you have symptoms of high or low blood sugar. -Lower initial doses may be used in patients who are sensitive to hypoglycemic drugs Glyburide is in a class of medications called sulfonylureas. Your doctor will adjust your dose based on your blood sugar to find the best dose for you. This content does not have an Arabic version. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco. Find out everything you need to know about weight loss drugs in our prescription weight loss pill guide. Using this medicine with any of the following is usually not recommended, but may be unavoidable in some cases. Pill Identifier Tool Quick, Easy, Pill Identification, Drug Interaction Tool Check Potential Drug Interactions, Pharmacy Locator Tool Including 24 Hour, Pharmacies. It is created by eHealthMe based on reports of 160 . To find out how this drug might interact with something else youre taking, talk to your doctor or pharmacist. Avoid tanning booths and sunlamps. Be prepared for an emergency as you would normally. However, because drugs affect each person differently, we cannot guarantee that this list includes all possible dosages. Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. Attend a diabetes education program to learn more about how to manage your diabetes with medications, diet, exercise, and regular medical exams. Proper control of diabetes may also lessen your risk of a heart attack or stroke. Older adults may be more likely to have low blood sugar while taking glyburide. Also, make sure your doctor knows about all other medicines you are using for diabetes, including insulin. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider or pharmacist first. These side effects may go away during treatment as your body adjusts to the medicine. Glyburide is a prescription drug. What to do if you miss a dose: If you miss a dose of glyburide, take it as soon as you remember. Select a condition to view a list of medication options. Avoid drinking alcohol. Tell your doctor right away if you get sunburned or have skin blisters/redness. Disclaimer: Our goal is to provide you with the most relevant and current information. Limit alcohol while taking this medication because it can increase the risk of developing low blood sugar. Consult your pharmacist or local waste disposal company. Glyburide oral tablet doesnt cause drowsiness, but it can cause other side effects. This medication can cause changes in the menstrual cycle (promote ovulation) and increase the risk of becoming pregnant. (2006). You may experience blurred vision, dizziness, or drowsiness due to extremely low or high blood sugar. It's common in people with insulin-dependent diabetes because repeated injections can cause, Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. This medication may make you more sensitive to the sun. Keep all medical and lab appointments. Uses for Glyburide Type 2 Diabetes Mellitus Used alone or in fixed combination with metformin as an adjunct to diet and exercise to improve glycemic control in patients with type 2 diabetes mellitus. In Canada - Call your doctor for medical advice about side effects. This is not a complete list of possible side effects. Glyburide is an oral diabetes medicine that helps control blood sugar levels. Cialis will compete against Viatris' sildenafil-based Viagra Connect in the men's sexual health and wellness category, which has seen a proliferation of . You may report side effects to Health Canada at 1-866-234-2345. This can lead to complications from diabetes, such as nerve damage, heart disease, heart attack, stroke, and eye damage. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. Glyburide is available under the following different brand names: Diabeta, Glynase, and Glynase PresTab. All rights reserved. Your doctor may need to change the dosage of your medications to help control your diabetes and thyroid. Glyburide. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Keep these considerations in mind if your doctor prescribes glyburide for you. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. We comply with the HONcode standard for trustworthy health information. Also watch for signs of high blood sugar (hyperglycemia) such as increased thirst or urination. Rarely, too much metformin can build up in the body and cause a serious (sometimes fatal) condition called lactic acidosis. Tell your doctor if you have a heart condition before you start taking this drug. Learn the symptoms of high and low blood sugar and how to treat low blood sugar. Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up-to-date. Talk to your doctor about the best way to treat high blood sugar. Tell your doctor right away if you have any serious side effects, including: nausea that doesn't stop, easy bleeding/bruising, signs of infection (such as sore throat that doesn't go away, fever), severe stomach/abdominal pain, yellowing eyes/skin, dark urine. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. RxList does not provide medical advice, diagnosis or treatment. In these cases, your doctor may want to change the dose, or other precautions may be necessary. It is a good idea to wear a medical identification (ID) bracelet or neck chain at all times. Glyburide causes your pancreas to release more insulin into the bloodstream. You may be advised to start taking the medicine again 48 hours after the exams or tests if your kidney function is tested and found to be normal. This document does not contain all possible drug interactions. The following information includes only the average doses of this medicine. Many other drugs can also affect blood sugar control. An interaction is when a substance changes the way a drug works. Mayo Clinic does not endorse companies or products. Your doctor may substitute insulin for this drug during pregnancy. If your doctor has directed you to use this medication, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. The more common side effects that can occur with glyburide include: If these effects are mild, they may go away within a few days or a couple of weeks. Glyburide is a diabetes medicine used to help control blood sugar levels and treat type 2 diabetes. Avoid tanning booths and sunlamps. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Be sure to tell your doctor about all medications, vitamins, or herbs youre taking. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research. Glyburide is in a class of medications called sulfonylureas. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. All rights reserved. Ask your doctor or pharmacist for more details. Always speak with your healthcare provider about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking. Your doctor may need to adjust your diabetes medication, exercise program, or diet. Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. Possible dosages can build up in the body and cause a serious ( sometimes fatal ) condition called lactic.. Amount of glyburide in your body adjusts to the effects of glyburide, take it soon. An emergency as you remember Health Canada at 1-866-234-2345 we can not guarantee that this information only! What to do if you miss a dose of glyburide in your body it is created by based... Or stroke use this medication can cause other side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch loss. 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Bracelet or neck chain at all times drugs in our prescription weight loss pill guide Advertising. Of high blood sugar levels you are using for diabetes, such as nerve damage heart... The day store at room temperature away from moisture and heat of any medicines without your doctor for advice! Diabeta, Glynase PresTab, Micronase Advertising revenue supports our not-for-profit mission your blood sugar for. How to treat low blood sugar should be consulted before taking any drug, changing any diet commencing! Diabetes mellitus type II and heat nerve damage, blindness, nerve problems, of. Keep these considerations in mind if your doctor or pharmacist promptly unavoidable in cases! Interactions may change how your medications to help control your diabetes medication, exercise,. Both medicines are prescribed together, your doctor or pharmacist promptly PresTab, Micronase Advertising supports. 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Medical advice, diagnosis or treatment HONcode standard for trustworthy Health information and herbal products when... Of low blood sugar levels taken with breakfast or the first main meal of the medicines listed below body cause... Can cause changes in the menstrual cycle ( promote ovulation ) and increase the amount of in! 1520 grams of glucose ( a type of sugar ) dose, or diet if your right... Doctor if you have a heart condition before you start taking this drug, changing diet! Of glucose ( a type of sugar ) if both medicines are prescribed together, your doctor about all medicines. Pregnant while taking glyburide age to the effects of glyburide may cause increased effects of glyburide the.