Use Caution/Monitor. Monitor Closely (1)erythromycin base will increase the level or effect of pioglitazone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. Mechanism: decreased hypoglycemia induced catecholamine production.clonidine, pioglitazone. Use Caution/Monitor. Minor/Significance Unknown. Use Caution/Monitor. Use Caution/Monitor. Minor/Significance Unknown. Either increases effects of the other by pharmacodynamic synergism. Other (see comment). indomethacin increases effects of glimepiride by unknown mechanism. Inhibits CYP2C8/2C9; use smallest recommended doses for substrates and monitor. Comment: Atypical antipsychotics have been associated with hyperglycemia that may alter blood glucose control; monitor glucose levels closely. Use Caution/Monitor. Use Caution/Monitor. Comment: Excessive EtOH consumption may alter glycemic control. Thiazide dosage >50 mg/day may increase blood glucose. This page includes all the important details about this product, including . Either increases effects of the other by pharmacodynamic synergism. Minor (1)efavirenz will decrease the level or effect of pioglitazone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. triamcinolone acetonide injectable suspension decreases effects of pioglitazone by pharmacodynamic antagonism. glimepiride, insulin lispro. This medicine could make you sunburn more easily. Minor/Significance Unknown. Minor/Significance Unknown. Insulin may increase the fluid retention associated with thiazolidinediones (peroxisome proliferator-activated receptor [PPAR]-gamma agonists). Minor/Significance Unknown. glimepiride increases toxicity of aminolevulinic acid topical by pharmacodynamic synergism. Minor/Significance Unknown. Talk with your doctor about ways to keep your bones healthy. Use Caution/Monitor. The product's dosage form is tablet and is administered via oral form. Comment: Atypical antipsychotics have been associated with hyperglycemia that may alter blood glucose control; monitor glucose levels closely. ciprofloxacin increases effects of glimepiride by pharmacodynamic synergism. Minor/Significance Unknown. Risk of hypoglycemia. Potential dysglycemia. gemifloxacin increases effects of glimepiride by pharmacodynamic synergism. Minor/Significance Unknown. Use Caution/Monitor. Monitor Closely (2)glimepiride, insulin isophane human/insulin regular human. Comment: Atypical antipsychotics have been associated with hyperglycemia that may alter blood glucose control; monitor glucose levels closely. Use Caution/Monitor. Use Caution/Monitor. Follow your doctor's instructions about using this medicine if you are pregnant or you become pregnant. Use Caution/Monitor. ciprofloxacin increases effects of pioglitazone by pharmacodynamic synergism. Minor/Significance Unknown. aprepitant will increase the level or effect of pioglitazone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. pentobarbital will decrease the level or effect of pioglitazone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. pioglitazone, insulin detemir. pioglitazone will increase the level or effect of selexipag by decreasing metabolism. Use Caution/Monitor. nortriptyline increases effects of glimepiride by pharmacodynamic synergism. 6476430230. pioglitazone, insulin lispro. ketotifen, ophthalmic, pioglitazone. Consider reducing the dose when concomitantly using CYP2C9 substrates. Use Caution/Monitor. Minor/Significance Unknown. Minor/Significance Unknown. nevirapine will decrease the level or effect of pioglitazone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. This drug is available at the lowest co-pay. Contraindicated. Gatifloxacin is most likely to produce dysglycemia; moxifloxacin is least likely. Antidiabetic agents are often used in combination; dosage adjustments may be required when initiating or discontinuing antidiabetic agents. Use Caution/Monitor. Either increases effects of the other by pharmacodynamic synergism. Use Caution/Monitor. Hypoglycemic effects may be increased. Other (see comment). Minor/Significance Unknown. Mechanism: unspecified interaction mechanism. rifapentine decreases levels of glimepiride by increasing metabolism. Use Caution/Monitor. Comment: Tipranavir's effect on oral hypoglycemics via hepatic CYP2C9 unknown; carefully monitor blood glucose. REPORT ADVERSE EVENTS | Recalls | Recalls It is available as a single product containing 2 medicationspioglitazone and glimepiride . Modify Therapy/Monitor Closely. Monitor Closely (1)timolol decreases effects of glimepiride by pharmacodynamic antagonism. Minor/Significance Unknown. Minor/Significance Unknown. cimetidine will increase the level or effect of pioglitazone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. When patients are administered peginterferon alpha-2b with CYP2C9 substrates, the therapeutic effect of these drugs may be altered. Gatifloxacin is most likely to produce dysglycemia; moxifloxacin is least likely.ofloxacin increases effects of pioglitazone by pharmacodynamic synergism. Use Caution/Monitor.Minor (1)fluconazole will increase the level or effect of pioglitazone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Antidiabetic agents are often used in combination; dosage adjustments may be required when initiating or discontinuing antidiabetic agents. Use Caution/Monitor.Minor (1)marijuana will increase the level or effect of pioglitazone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. Minor/Significance Unknown. Insulin may increase the fluid retention associated with thiazolidinediones (peroxisome proliferator-activated receptor [PPAR]-gamma agonists). potassium acid phosphate increases effects of pioglitazone by pharmacodynamic synergism. cornsilk increases effects of pioglitazone by pharmacodynamic synergism. Minor/Significance Unknown. pioglitazone will increase the level or effect of baricitinib by decreasing elimination. Minor/Significance Unknown. Share cases and questions with Physicians on Medscape consult. Use Caution/Monitor. Increased risk of hypoglycemia when exenatide is used in combination with agents that induce hypoglycemia. Either increases effects of the other by pharmacodynamic synergism. Coadministration of metreleptin with insulin and/or insulin secretagogues (eg, sulfonylureas, meglitinide derivatives) may increase risk for hypoglycemia; may require lower dose of insulin or insulin secretagogue. Mechanism: decreased hypoglycemia induced catecholamine production. Minor (2)doxepin increases effects of glimepiride by pharmacodynamic synergism. Minor/Significance Unknown. bitter melon increases effects of glimepiride by pharmacodynamic synergism. Pioglitazone / Glimepiride Medicare Coverage and Co-Pay Details - GoodRx. Avoid concomitant use of inhibitors of the bile salt efflux pump (BSEP). Batch CBD Full-Spectrum Gummies. Monitor Closely (2)quetiapine, pioglitazone. asenapine, glimepiride. Avoid or Use Alternate Drug. rifapentine will decrease the level or effect of pioglitazone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Gatifloxacin is most likely to produce dysglycemia; moxifloxacin is least likely.gemifloxacin increases effects of pioglitazone by pharmacodynamic synergism. Theoretical interaction.eucalyptus increases effects of glimepiride by pharmacodynamic synergism. Minor (2)indapamide decreases effects of pioglitazone by pharmacodynamic antagonism. Inhibits CYP2C8/2C9; use smallest recommended doses for substrates and monitor. Monitor Closely (2)ketotifen, ophthalmic, glimepiride. Modify Therapy/Monitor Closely. Blood sugar levels can be affected by stress, illness, surgery, exercise, alcohol use, or skipping meals. Esta actitud por parte del paparazzi . serum concentration of glimepiride or pioglitazone or peak exposure (C. max) of pioglitazone. testosterone increases effects of glimepiride by pharmacodynamic synergism. Use Caution/Monitor. insulin glulisine increases toxicity of pioglitazone by unknown mechanism. Use Caution/Monitor. DUETACT (pioglitazone and glimepiride) (30 mg pioglitazone plus 2 mg glimepiride tablets for oral use. Use Caution/Monitor. Antidiabetic agents are often used in combination; dosage adjustments may be required when initiating or discontinuing antidiabetic agents. Serious - Use Alternative (1)pioglitazone will decrease the level or effect of pacritinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Duetact is used, along with diet and exercise, to treat people with type 2 diabetes. Talk with your doctor about your specific risk. lopinavir decreases effects of glimepiride by Other (see comment). Version: 6.02. isoniazid decreases effects of glimepiride by unspecified interaction mechanism. Monitor Closely (2)pioglitazone, insulin aspart protamine/insulin aspart. If concomitant use is necessary, monitor serum transaminases and bilirubin. Pioglitazone works by helping your body use insulin better. Monitor Closely (1)lixisenatide (DSC), glimepiride. Use Caution/Monitor. Comment: Closely monitor blood glucose when treated with antidiabetic agents. Other (see comment). Use Caution/Monitor. Concurrent use may increase risk of hypoglycemia; monitor glucose levels. Minor/Significance Unknown. Lonapegsomatropin may decrease insulin sensitivity, particularly at higher doses. Use Caution/Monitor. Non selective beta blockers may also mask the symptoms of hypoglycemia. Use Caution/Monitor. Increased risk of hypoglycemia (theoretical interaction). nettle increases effects of glimepiride by pharmacodynamic synergism. Minor/Significance Unknown. Medically reviewed by Philip Thornton, DipPharm. The first look at the 'middle aged Love Island' set has been released, which has already been nicknamed the 'Viagra House' by locals after single parents searched for love lixisenatide (DSC), glimepiride. fluconazole will increase the level or effect of pioglitazone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. .Minor (1)indinavir will increase the level or effect of pioglitazone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor (1)nevirapine will decrease the level or effect of pioglitazone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. 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