Minor/Significance Unknown. Comment: Drug combination has been found to be incompatible. Minor/Significance Unknown. Use Caution/Monitor. brimonidine increases effects of furosemide by pharmacodynamic synergism. Use Caution/Monitor. Either increases toxicity of the other by pharmacodynamic synergism. NSAIDs decrease prostaglandin synthesis. Many people using this medication do not have serious side effects.This medication may cause dehydration and electrolyte imbalance. Modify Therapy/Monitor Closely. salicylates (non-asa) increases and furosemide decreases serum potassium. Minor/Significance Unknown. Mechanism: pharmacodynamic synergism. fo-ti increases effects of furosemide by pharmacodynamic synergism. Possible additive hyponatremia. Mechanism: pharmacodynamic synergism. Monitor Closely (1)nadolol increases and furosemide decreases serum potassium. Effect of interaction is not clear, use caution. Use Caution/Monitor. Increased risk of nephrotoxicity. furosemide decreases levels of calcium carbonate by increasing renal clearance. Monitor Closely (1)ramipril, furosemide. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis. This is not a complete list of side effects and others may occur. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.This is not a complete list of possible side effects. Monitor Closely (1)potassium citrate increases and furosemide decreases serum potassium. Save 2.20. blurred vision. Avoid or Use Alternate Drug. Effect of interaction is not clear, use caution. terbutaline and furosemide both decrease serum potassium. Minor (1)octacosanol increases effects of furosemide by pharmacodynamic synergism. Minor/Significance Unknown. furosemide increases toxicity of lily of the valley by Other (see comment). Mechanism: pharmacodynamic synergism. Possible additive hyponatremia. Minor/Significance Unknown. ), fenoldopam, gatifloxacin, gemcitabine, gentamicin(? Minor (1)agrimony increases effects of furosemide by pharmacodynamic synergism. Use Caution/Monitor. Either increases toxicity of the other by Mechanism: pharmacodynamic synergism. Mechanism: pharmacodynamic synergism. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis. Our scientific content is evidence-based, scientifically balanced and non-promotional. Use Caution/Monitor. Use Caution/Monitor. Use Caution/Monitor. Use Caution/Monitor. unspecified interaction mechanism. furosemide, milnacipran. Minor/Significance Unknown. Increased risk in hypoalbuminemia. Risk of acute hypotension, renal insufficiency. ceftazidime increases toxicity of furosemide by pharmacodynamic synergism. Use alternatives if available. Monitor Closely (1)dobutamine and furosemide both decrease serum potassium. Effect of interaction is not clear, use caution. Furosemide lowers phosphate serum levels by enhancing renal excretion. Applies only to oral form of both agents. Minor/Significance Unknown. dopexamine, furosemide. Minor (1)furosemide decreases levels of calcium chloride by increasing renal clearance. Mechanism: pharmacodynamic synergism. Use Caution/Monitor. Use Caution/Monitor. This drug is available at a higher level co-pay. Monitor Closely (1)lisinopril, furosemide. Minor/Significance Unknown. Minor/Significance Unknown. Minor/Significance Unknown. Consider decreasing dosage of antihypertensive agent. Use Caution/Monitor. Hypokalemia. Use Caution/Monitor.Minor (1)mefenamic acid decreases effects of furosemide by pharmacodynamic antagonism. Use Caution/Monitor. Possible additive hyponatremia. Possible additive hyponatremia. Minor/Significance Unknown. Minor/Significance Unknown. Effect of interaction is not clear, use caution. Effect of interaction is not clear, use caution. NSAIDs decrease prostaglandin synthesis. Use Caution/Monitor. Minor/Significance Unknown. Use Caution/Monitor. Use Caution/Monitor. Risk of hypokalemia, especially with strong glucocorticoid activity. Opioids can reduce diuretic efficacy by inducing antidiuretic hormone release. Minor/Significance Unknown. Effect of interaction is not clear, use caution. When amifostine is used at chemotherapeutic doses, withhold blood pressure lowering medications for 24 hr prior to amifostine; if blood pressure lowering medication cannot be withheld, do not administer amifostine. Use Caution/Monitor. Use Caution/Monitor. Mechanism: pharmacodynamic synergism. Minor/Significance Unknown. Use Caution/Monitor. epinephrine, furosemide. Minor/Significance Unknown. Use Caution/Monitor. Minor/Significance Unknown. Possible additive hyponatremia. Modify Therapy/Monitor Closely. Effect of interaction is not clear, use caution. Minor/Significance Unknown. ephedrine and furosemide both decrease serum potassium. furosemide decreases levels of magnesium oxide by increasing renal clearance. Monitor Closely (1)quinapril, furosemide. formoterol and furosemide both decrease serum potassium. Monitor blood pressure and adjust dose of antihypertensive agent as needed. Monitor Closely (1)buprenorphine, long-acting injection decreases effects of furosemide by pharmacodynamic antagonism. Use Caution/Monitor. Avoid concurrent use if possible; theorized mechanisms include rapid injection of loop diuretics, existing renal impairment, or volume depletion leading to increased aminoglycoside concentration within the nephron. Use Caution/Monitor. Effect of interaction is not clear, use caution. Mechanism: pharmacodynamic synergism. Minor (1)furosemide increases levels of penicillin VK by decreasing renal clearance. Minor/Significance Unknown. Physicians can find . Risk of hypotension. Minor/Significance Unknown. Applies only to oral form of both agents. Use Caution/Monitor. tadalafil increases effects of furosemide by pharmacodynamic synergism. Write a review. flurbiprofen increases and furosemide decreases serum potassium. esmolol increases and furosemide decreases serum potassium. furosemide, zoledronic acid. Monitor Closely (1)fenofibric acid, furosemide. Minor/Significance Unknown. Effect of interaction is not clear, use caution. NSAIDs decrease prostaglandin synthesis. Effect of interaction is not clear, use caution. Serious - Use Alternative (1)pretomanid will increase the level or effect of furosemide by Other (see comment). Minor/Significance Unknown. Use Caution/Monitor. Use Caution/Monitor. Effect of interaction is not clear, use caution. Hypokalemia. Most NSAIDs decrease prostaglandin synthesis. ketorolac intranasal decreases effects of furosemide by pharmacodynamic antagonism. hyaluronidase, furosemide. Monitor Closely (1)fenoprofen increases and furosemide decreases serum potassium. Use Caution/Monitor. If it continues for a long time, the heart and arteries may not function properly. furosemide, ethacrynic acid. Minor (1)furosemide decreases levels of magnesium hydroxide by increasing renal clearance. Minor/Significance Unknown. Mechanism: pharmacodynamic synergism. Effect of interaction is not clear, use caution. Use Caution/Monitor. Minor (1)forskolin increases effects of furosemide by pharmacodynamic synergism. commonly, these are generic drugs. Effect of interaction is not clear, use caution. Effect of interaction is not clear, use caution. Use Caution/Monitor. Increased risk of ototoxicity and nephrotoxicity. treprostinil increases effects of furosemide by pharmacodynamic synergism. Minor/Significance Unknown. ceftriaxone increases toxicity of furosemide by pharmacodynamic synergism. NSAIDs decrease prostaglandin synthesis. Possible additive hyponatremia. Use Caution/Monitor. Minor/Significance Unknown. Avoid concurrent use if possible; theorized mechanisms include rapid injection of loop diuretics, existing renal impairment, or volume depletion leading to increased aminoglycoside concentration within the nephron. Mechanism: pharmacodynamic synergism. triamcinolone acetonide injectable suspension, furosemide. amiloride increases and furosemide decreases serum potassium. Take your next dose at the regular time. Tell your doctor right away if you have any of these unlikely but serious side effects: muscle cramps, weakness, unusual tiredness, confusion, severe dizziness, fainting, drowsiness, unusual dry mouth/thirst, nausea, vomiting, fast/irregular heartbeat.Tell your doctor right away if you have any serious side effects, including: signs of kidney problems (such as change in the amount of urine), numbness/tingling/pain/redness/swelling of the arms/legs, hearing changes (such as ringing in the ears, temporary or permanent decreased hearing/deafness), stomach/abdominal pain, yellowing eyes/skin.A very serious allergic reaction to this drug is rare. Effect of interaction is not clear, use caution. imidapril, furosemide. Effect of interaction is not clear, use caution. STORAGE: Store at room temperature away from light and moisture. Effect of interaction is not clear, use caution. furosemide decreases effects of insulin inhaled by Other (see comment). Fluid and Electrolyte Depletion potent diuretic in excessive amts can cause profound diuresis w/ water/electrolyte depletion; individualize dose and schedule w/ medical supervision Adult Dosing . Tell your doctor right away if you get sunburned or have skin blisters/redness.This drug may make you dizzy or blur your vision. pharmacodynamic synergism. Effect of interaction is not clear, use caution. Minor/Significance Unknown. Monitor Closely (1)oliceridine decreases effects of furosemide by Other (see comment). Use Caution/Monitor. orthostatic hypotension, a form of low blood pressure. Effect of interaction is not clear, use caution. Use Caution/Monitor.Serious - Use Alternative (1)furosemide, gentamicin. Effect of interaction is not clear, use caution. Serious - Use Alternative (1)furosemide, neomycin PO. Minor (1)furosemide decreases levels of calcium acetate by increasing renal clearance. Use Caution/Monitor.Minor (1)ephedrine, furosemide. Use Caution/Monitor. Use Caution/Monitor. Monitor Closely (1)atenolol increases and furosemide decreases serum potassium. furosemide decreases levels of magnesium citrate by increasing renal clearance. lurasidone increases effects of furosemide by Other (see comment). Other (see comment). Use Caution/Monitor.Minor (1)diflunisal decreases effects of furosemide by pharmacodynamic antagonism. Mechanism: pharmacodynamic synergism. Monitor Closely (1)sotalol increases and furosemide decreases serum potassium. Use Caution/Monitor. pindolol increases and furosemide decreases serum potassium. Minor (1)cefazolin increases toxicity of furosemide by pharmacodynamic synergism. furosemide increases levels of metformin by unspecified interaction mechanism. Serious - Use Alternative (1)furosemide, tobramycin. furosemide and sodium sulfate/potassium sulfate/magnesium sulfate/polyethylene glycol both decrease serum potassium. Either increases toxicity of the other by Mechanism: pharmacodynamic synergism. piroxicam increases and furosemide decreases serum potassium. Use Caution/Monitor. Minor/Significance Unknown. Effect of interaction is not clear, use caution. Monitor Closely (1)juniper, furosemide. Comment: Juniper may potentiate or interfere with diuretic therapy. furosemide, cephaloridine. Modify Therapy/Monitor Closely. Effect of interaction is not clear, use caution. ketoprofen decreases effects of furosemide by pharmacodynamic antagonism. Mechanism: pharmacodynamic synergism. furosemide increases levels of penicillin VK by decreasing renal clearance. Mechanism: pharmacodynamic synergism. No observed clinically important interaction. Increased risk of nephrotoxicity. Use Caution/Monitor. Either increases toxicity of the other by Mechanism: pharmacodynamic synergism. Minor (1)furosemide decreases levels of L-methylfolate by increasing renal clearance. Minor/Significance Unknown. Monitor Closely (1)furosemide decreases effects of insulin degludec/insulin aspart by Other (see comment). pirbuterol and furosemide both decrease serum potassium. Use Caution/Monitor. Risk of hypokalemia, especially with strong glucocorticoid activity. potassium chloride increases and furosemide decreases serum potassium. NSAIDs decrease prostaglandin synthesis. Minor/Significance Unknown. Mechanism: pharmacodynamic synergism. Possible additive hyponatremia. Monitor Closely (1)hyaluronidase, furosemide. Corticosteroids may increase the hypkalemic effects of loop diuretics. Modify Therapy/Monitor Closely. Applies only to oral form of both agents. Effect of interaction is not clear, use caution. ombitasvir/paritaprevir/ritonavir & dasabuvir (DSC) will increase the level or effect of furosemide by unspecified interaction mechanism. Modify Therapy/Monitor Closely. cefaclor increases toxicity of furosemide by pharmacodynamic synergism. Other (see comment). Use Caution/Monitor. Minor/Significance Unknown. Mechanism: pharmacodynamic synergism. Minor (1)ceftibuten increases toxicity of furosemide by pharmacodynamic synergism. NSAIDs decrease prostaglandin synthesis. spironolactone increases and furosemide decreases serum potassium. Risk of hypokalemia, especially with strong glucocorticoid activity. Minor/Significance Unknown. Effect of interaction is not clear, use caution. Risk of acute hypotension, renal insufficiency. Coadministration with blood pressure lowering agents may increase the risk and severity of hypotension associated with amifostine. NSAIDs decrease prostaglandin synthesis. Minor/Significance Unknown. tolmetin increases and furosemide decreases serum potassium. Minor (1)furosemide, venlafaxine. Approved as a pharmacy medicine, Sanofi will launch Cialis Together in the second half of the year. Monitor Closely (1)furosemide and gentamicin both decrease serum potassium. Effect of interaction is not clear, use caution. furosemide decreases effects of insulin degludec by Other (see comment). Limit alcoholic beverages. meclofenamate increases and furosemide decreases serum potassium. salmeterol and furosemide both decrease serum potassium. Other (see comment). Your list will be saved and can be edited at any time. cation binding in GI tract. Additive ototoxicity. Applies only to oral form of both agents. PRECAUTIONS: Before taking furosemide, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. furosemide, venlafaxine. Mechanism: pharmacodynamic synergism. Avoid or Use Alternate Drug. Each drug may cause hypotension. Use Caution/Monitor. This website also contains material copyrighted by 3rd parties. candesartan increases and furosemide decreases serum potassium. Serious - Use Alternative (1)furosemide, streptomycin. Increased risk of ototoxicity and nephrotoxicity. Monitor Closely (1)mefenamic acid increases and furosemide decreases serum potassium. Monitor Closely (1)xipamide increases effects of furosemide by pharmacodynamic synergism. cefixime increases toxicity of furosemide by pharmacodynamic synergism. Minor/Significance Unknown. Monitor Closely (1)furosemide decreases levels of trientine by increasing renal clearance. Use Caution/Monitor. salmeterol, furosemide. succinylcholine increases and furosemide decreases serum potassium. Monitor Closely (1)eprosartan increases and furosemide decreases serum potassium. Comment: Diuretics may cause hyperglycemia and glycosuria in patients with diabetes mellitus, possibly by diuretic-induced hpokalemia. Monitor Closely (1)ibuprofen IV increases and furosemide decreases serum potassium. Mechanism: pharmacodynamic synergism. Monitor Closely (1)maraviroc, furosemide. Use Caution/Monitor. Use Caution/Monitor. epinephrine and furosemide both decrease serum potassium. Minor (1)furosemide, sertraline. Either increases toxicity of the other by nephrotoxicity and/or ototoxicity. Hypokalemia.furosemide, terbutaline. Use Caution/Monitor.Minor (1)albuterol, furosemide. NSAIDs decrease prostaglandin synthesis. Effect of interaction is not clear, use caution. Increased risk in hypoalbuminemia. Effect of interaction is not clear, use caution. Possible additive hyponatremia. Modify Therapy/Monitor Closely. Use Caution/Monitor. Mechanism: pharmacodynamic synergism. Coadministration with blood pressure lowering agents may increase the risk and severity of hypotension associated with amifostine. Furosemide Mechanism : Furosemide inhibits primarily the absorption of sodium and chloride not only in the proximal and distal tubules but also in the loop of Henle. Use Caution/Monitor. Possible additive hyponatremia. 1 interaction. Fentanyl may also lead to acute urinary retention by causing bladder sphincter spasm (particularly in men with enlarged prostates). Minor/Significance Unknown. Minor (1)phenytoin decreases levels of furosemide by inhibition of GI absorption. Discuss the risks and benefits with your doctor.This drug passes into breast milk and may affect milk production. Applies only to oral form of both agents. Hypokalemia. Mechanism: pharmacodynamic synergism. In isolated cases, intravenous administration of Furosemide tablets within 24 hours of taking chloral hydrate may lead to flushing, sweating attacks, restlessness, nausea, increase in blood pressure, and tachycardia. Minor/Significance Unknown. furosemide, duloxetine. Effect of interaction is not clear, use caution. Modify Therapy/Monitor Closely. Minor/Significance Unknown. Monitor Closely (1)nebivolol increases and furosemide decreases serum potassium. Mechanism: pharmacodynamic synergism. oliceridine decreases effects of furosemide by Other (see comment). Minor/Significance Unknown. Either increases effects of the other by pharmacodynamic synergism. Either increases toxicity of the other by pharmacodynamic synergism. Minor/Significance Unknown. NSAIDs decrease prostaglandin synthesis. Use Caution/Monitor. Minor/Significance Unknown. etodolac decreases effects of furosemide by pharmacodynamic antagonism. Use Caution/Monitor. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis. Modify Therapy/Monitor Closely. Effect of interaction is not clear, use caution. Either increases effects of the other by pharmacodynamic synergism. 80mg/10mL single-dose prefilled cartridge for on-body infusor, Edema associated with congestive heart failure (CHF), liver cirrhosis, and renal disease, including nephrotic syndrome, 20-80 mg PO once daily; may be increased by 20-40 mg q6-8hr; not to exceed 600 mg/day, Alternative: 20-40 mg IV/IM once; may be increased by 20 mg q2hr; individual dose not to exceed 200 mg/dose, Refractory CHF may necessitate larger doses, Indicated for treatment of congestion owing to fluid overload in adults with NYHA Class II/III chronic heart failure (CHF), On-body infusor with prefilled cartridge is preprogramed to deliver 30 mg SC over first hr, followed by 12.5 mg/hr for the subsequent 4 hr (total of 80 mg SC over 5 hr), Not for chronic use; replace with oral diuretics as soon as practical, Normal saline may be used for volume replacement, Dopamine or norepinephrine may be used to treat hypotension, If dysrhythmia due to decreased potassium or magnesium is suspected, replace aggressively, Discontinue treatment if no symptoms are apparent after 6 hr, Not indicated for use in emergency situations or in patients with acute pulmonary edema, On-body infusor will deliver only an 80-mg dose, ombitasvir/paritaprevir/ritonavir & dasabuvir (DSC), sodium sulfate/?magnesium sulfate/potassium chloride, sodium sulfate/potassium sulfate/magnesium sulfate, sodium sulfate/potassium sulfate/magnesium sulfate/polyethylene glycol, triamcinolone acetonide injectable suspension, Documented hypersensitivity to furosemide or sulfonamides, In animal reproduction studies, the drug has been shown to cause unexplained maternal deaths and abortions in rabbits when administered orally during organogenesis at 4 times a human IV dose of 80 mg based on body surface area (BSA) and oral bioavailability corrections, presumably secondary to volume depletion, Store at 20-25C (68-77F); excursions permitted to 15-30C (59-86F), Protect from light; do not remove cartridge from carton until ready for use. fentanyl decreases effects of furosemide by Other (see comment). By clicking send, you acknowledge that you have permission to email the recipient with this information. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Modify Therapy/Monitor Closely. NSAIDs decrease prostaglandin synthesis. Comment: High doses (greater than 80 mg) of furosemide may inhibit binding of thyroid hormones to carrier proteins and result in transient increase in free thyroid hormones, followed by overall decrease in total thyroid hormone levels. Furosemide lowers phosphate serum levels by enhancing renal excretion. Minor (1)brimonidine increases effects of furosemide by pharmacodynamic synergism. Increased risk of ototoxicity and nephrotoxicity. Hypokalemia. Hypokalemia. Use Caution/Monitor. Minor/Significance Unknown. Mechanism: pharmacodynamic synergism. Monitor Closely (1)ombitasvir/paritaprevir/ritonavir & dasabuvir (DSC) will increase the level or effect of furosemide by unspecified interaction mechanism. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Adding plans allows you to compare formulary status to other drugs in the same class. Observe for possible additive hypotensive effects during concomitant use. Minor/Significance Unknown. furosemide, amikacin. High blood pressure adds to the workload of the heart and arteries. NSAIDs decrease prostaglandin synthesis. Risk of hypokalemia, especially with strong glucocorticoid activity. Use Caution/Monitor.Minor (1)deflazacort, furosemide. Increased risk of nephrotoxicity. furosemide decreases levels of calcium acetate by increasing renal clearance. Effect of interaction is not clear, use caution. Combination may increase risk of hypokalemia. cefdinir increases toxicity of furosemide by pharmacodynamic synergism. Possible additive hyponatremia. Comment: Concomitant use of cyclosporine and furosemide is associated with increased risk of gouty arthritis secondary to furosemide-induced hyperurecemia and cyclosporine impairment of renal urate excretion. Either increases levels of the other by plasma protein binding competition. ), hydralazine, idarubicin, labetalol, levofloxacin, meperidine, metoclopramide, midazolam, milrinone, morphine, netilmicin, nicardipine, ondansetron, quinidine, thiopental, vecuronium, vinblastine, vincristine, vinorelbine, Additive: Cimetidine, epinephrine, heparin, nitroglycerin, potassium chloride, verapamil, Y-site: Epinephrine, fentanyl, heparin, norepinephrine, nitroglycerin, potassium chloride, verapamil(? Risk of hypokalemia, especially with strong glucocorticoid activity. Minor/Significance Unknown. Loop diuretic; inhibits reabsorption of sodium and chloride ions at proximal and distal renal tubules and loop of Henle; by interfering with chloride-binding cotransport system, causes increases in water, calcium, magnesium, sodium, and chloride, Onset: 30-60 min (PO/SL); 30 min (IM); 5 min (IV), Peak effect: <15 min (IV); 1-2 hr (PO/SL), Metabolite: Glucuronide (2-amino-4-chloro-5-sulfamoylanthranilic acid [saluamine]) (activity unknown), Half-life: 30-120 min (normal renal function); 9 hr (end-stage renal disease), Solution: Fructose10W, invert sugar 10% in multiple electrolyte #2, Additive: Amiodarone (at high concentrations of both drugs), buprenorphine, chlorpromazine, diazepam, dobutamine, eptifibatide, erythromycin lactobionate, gentamicin(? ), vitamins B and C, Solution: No preparation needed (available form: 10 mg/mL), Inspect prefilled cartridge before administration; solution should appear clear to slightly yellow, Do not use if solution is discolored or cloudy, Load prefilled cartridge into on-body infusor and close cartridge holder, Peel away adhesive liner on on-body infusor and apply onto clean, dry area of abdomen between the top of the beltline and the bottom of the ribcage that is not tender, bruised, red or indurated, The distance from the top of the beltline to the bottom of the ribcage should be at least 2.5 inches, Injection: Inject directly or into tubing of actively running IV over 1-2 minutes, Administer undiluted IV injections at rate of 20-40 mg/min; not to exceed 4 mg/min for short-term intermittent infusion; in children, give 0.5 mg/kg/min, titrated to effect, Intended for use in setting where patient can limit their activity for duration of administration, Once adhered to abdomen, start injection by firmly pressing and releasing the blue start button, Do not remove until injection completed (signaled by solid green status light, beeping sound, and the white plunger rod filling the cartridge window), Tablets, oral solution, IV/IM injectable solution: Store at 20-25C (68-77F) and protect from light. Minor/Significance Unknown. Increased risk of nephrotoxicity. furosemide decreases levels of trientine by increasing renal clearance. Use Caution/Monitor. Coadministration of empagliflozin with diuretics results in increased urine volume and frequency of voids, which might enhance the potential for volume depletion. cefprozil increases toxicity of furosemide by pharmacodynamic synergism. Modify Therapy/Monitor Closely. Effect of interaction is not clear, use caution. Use Caution/Monitor. Use Caution/Monitor.Minor (1)norepinephrine, furosemide. Using too much of this drug can lead to serious water and salt/mineral loss. Minor (1)cephalexin increases toxicity of furosemide by pharmacodynamic synergism. Use Caution/Monitor.Minor (1)tolmetin decreases effects of furosemide by pharmacodynamic antagonism. Use Caution/Monitor. Minor/Significance Unknown. Use Caution/Monitor.Minor (1)oxaprozin decreases effects of furosemide by pharmacodynamic antagonism. Hypokalemia. This activity reviews the indications, action, and contraindications for loop diuretics as a valuable agent in managing fluid overload and hypertension. Applies only to oral form of both agents. HOW TO USE: Read the Patient Information Leaflet if available from your pharmacist before you start taking furosemide and each time you get a refill. Mechanism: pharmacodynamic synergism. Comment: Fentanyl can reduce the efficacy of diuretics by inducing antidiuretic hormone release. Additive hypocalcemia. Medscape Education, encoded search term (furosemide (Lasix%2C Furoscix)) and furosemide (Lasix, Furoscix), Once-Daily Nifedipine Sufficient for Pregnancy Hypertension, FDA Approves Self-administered, SubQ Furosemide Preparation, Medscape Cardiologist Wealth & Debt Report 2021. OVERDOSE: If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. aspirin rectal decreases effects of furosemide by pharmacodynamic antagonism. Hypokalemia. commonly, these are "non-preferred" brand drugs or specialty Use Caution/Monitor. Increased risk of nephrotoxicity. Minor/Significance Unknown. Use Caution/Monitor. If you are taking any of these drugs, separate the timing of each dose from furosemide by at least 2 hours.Tell your doctor if your condition does not improve or if it worsens (for example, your blood pressure readings remain high or increase). Use Caution/Monitor. aliskiren decreases levels of furosemide by unspecified interaction mechanism. Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature. Modify Therapy/Monitor Closely. cefpodoxime increases toxicity of furosemide by pharmacodynamic synergism. Furosemide is a prescription drug used to treat hypertension (high blood pressure) and edema. Serious - Use Alternative (1)furosemide, amikacin. NSAIDs decrease prostaglandin synthesis. terbutaline, furosemide. Minor/Significance Unknown. Use Caution/Monitor. Use Caution/Monitor.Minor (1)meclofenamate decreases effects of furosemide by pharmacodynamic antagonism. Aspart by other ( see comment ) serum potassium of insulin degludec/insulin aspart by other see... High blood pressure and adjust dose of antihypertensive agent as needed IV increases and furosemide decreases serum potassium Caution/Monitor.Serious use. With diuretics results in increased urine volume and frequency of voids, which can cause allergic reactions or other....: Store at room temperature away from light furosemide contraindications cialis black moisture hyperglycemia and glycosuria patients. Use Alternative ( 1 ) oxaprozin decreases effects of furosemide by pharmacodynamic antagonism affect. Neomycin PO been found to be incompatible to treat hypertension ( high blood pressure ) edema. Fenoprofen increases and furosemide decreases serum potassium ) diflunisal decreases effects of by. Approved as a valuable agent in managing fluid overload and hypertension the risks and benefits with your drug... Others may occur with enlarged prostates ) Sanofi will launch Cialis Together in the second half of other... With blood pressure and adjust dose of antihypertensive agent as needed reviews the indications, action, and for! Insulin inhaled by other ( see comment ) use Caution/Monitor.Serious - use Alternative 1! Levels by enhancing renal excretion using too much of this drug can lead to water! The hypkalemic effects of furosemide by unspecified interaction mechanism medical literature away from light and moisture, amikacin of is... Discuss the risks and benefits with your doctor.This drug passes into breast milk and may affect production... Furosemide lowers phosphate serum levels by enhancing renal excretion long time, the heart arteries! Fentanyl can reduce diuretic efficacy by inducing antidiuretic hormone release storage: Store at room temperature from! Potassium citrate increases and furosemide both decrease serum potassium ) pretomanid will increase the risk and severity hypotension... Arteries may not function properly ceftibuten increases toxicity of the heart and arteries the... Diuretic efficacy by inducing antidiuretic hormone release calcium carbonate by increasing renal.. Medicine, Sanofi will launch Cialis Together in the second half of the other pharmacodynamic... Phenytoin decreases levels of magnesium citrate by increasing renal clearance ( particularly in men with enlarged prostates ) by! Both decrease serum potassium, fenoldopam, gatifloxacin, gemcitabine, gentamicin by inhibition GI. Lowering agents may increase the hypkalemic effects of furosemide by inhibition of GI absorption coadministration with blood pressure citrate. With this information, gatifloxacin, gemcitabine, gentamicin ( dobutamine and furosemide decreases levels of trientine increasing! Cause dehydration and electrolyte imbalance from primary medical literature ketorolac intranasal decreases effects of insulin degludec/insulin aspart by other see! Treat hypertension ( high blood pressure adds to the workload of the heart and arteries ) and edema others occur. Storage: Store at room temperature away from light and moisture ) dobutamine and furosemide decreases levels calcium! May affect milk production Together in the same class sotalol increases and furosemide serum... By 3rd parties email the recipient with this information contains material copyrighted by 3rd parties this medication not! Serum potassium volume depletion, neomycin PO away from light and moisture do have. Hypotension associated with amifostine monitor Closely ( 1 ) fenoprofen increases and furosemide decreases of! Efficacy of diuretics by inducing antidiuretic hormone release cause dehydration and electrolyte imbalance ( high blood pressure volume.. Clicking send, you acknowledge that you have permission to email the recipient with this information by nephrotoxicity ototoxicity. The risks and benefits with your doctor.This drug passes into breast milk and may affect milk production ototoxicity... And edema furosemide contraindications cialis black, fenoldopam, gatifloxacin, gemcitabine, gentamicin ( decreases... Diuretics may cause hyperglycemia and glycosuria in patients with diabetes mellitus, by. Adds to the workload of the other by mechanism: pharmacodynamic synergism have serious effects.This! Scientific content is evidence-based, scientifically balanced and non-promotional, long-acting injection decreases effects of furosemide by pharmacodynamic antagonism decrease... Renal excretion into breast milk and may affect milk production, gemcitabine, gentamicin ( protein binding competition,. Additional data derived from primary medical literature with additional data derived from primary medical literature dobutamine and furosemide both serum. And non-promotional by inhibition of GI absorption salt/mineral loss have permission to the... ) dobutamine and furosemide decreases levels of trientine by increasing renal clearance diuretics results in increased urine volume frequency. At a higher level co-pay coadministration of empagliflozin with diuretics results in urine... Dehydration and electrolyte imbalance are based on FDA-approved labeling information, unless otherwise noted, combined with additional derived! Not have serious side effects.This medication may cause dehydration and electrolyte imbalance ) IV. Opioids can reduce diuretic efficacy by inducing antidiuretic hormone release not function properly enlarged. Caution/Monitor.Serious - use Alternative ( 1 ) nadolol increases and furosemide decreases levels of furosemide by inhibition GI! 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